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ONTOLOGY REPORT - ANNOTATIONS

Term:cytotoxic T cell degranulation
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Accession:GO:0043316 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
Synonyms:exact_synonym: cytotoxic T cell granule exocytosis;   cytotoxic T lymphocyte degranulation;   cytotoxic T lymphocyte granule exocytosis


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cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164 		JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:18424730)
GO_REF:0000024		 RGD
UniProt		 PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    immune system process 2627
      immune effector process 710
        leukocyte degranulation 95
          cytotoxic T cell degranulation 4
            negative regulation of cytotoxic T cell degranulation 2
            positive regulation of cytotoxic T cell degranulation 0
            regulation of cytotoxic T cell degranulation + 2
Path 2
Term Annotations click to browse term
  biological_process 19818
    localization 5601
      establishment of localization 4940
        transport 4764
          secretion 1184
            secretion by cell 992
              exocytosis 397
                regulated exocytosis 275
                  leukocyte degranulation 95
                    cytotoxic T cell degranulation 4
                      negative regulation of cytotoxic T cell degranulation 2
                      positive regulation of cytotoxic T cell degranulation 0
                      regulation of cytotoxic T cell degranulation + 2
paths to the root