Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cytotoxic T cell degranulation
go back to main search page
Accession:GO:0043316 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
Synonyms:exact_synonym: cytotoxic T cell granule exocytosis;   cytotoxic T lymphocyte degranulation;   cytotoxic T lymphocyte granule exocytosis



show annotations for term's descendants           Sort by:
 
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    immune system process 2730
      immune effector process 678
        leukocyte degranulation 92
          cytotoxic T cell degranulation 4
            negative regulation of cytotoxic T cell degranulation 2
            positive regulation of cytotoxic T cell degranulation 0
            regulation of cytotoxic T cell degranulation + 2
Path 2
Term Annotations click to browse term
  biological_process 18734
    localization 5475
      establishment of localization 4825
        transport 4663
          export from cell 1054
            secretion by cell 982
              exocytosis 427
                regulated exocytosis 297
                  leukocyte degranulation 92
                    cytotoxic T cell degranulation 4
                      negative regulation of cytotoxic T cell degranulation 2
                      positive regulation of cytotoxic T cell degranulation 0
                      regulation of cytotoxic T cell degranulation + 2
paths to the root