Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RT1-M5 (RT1 class Ib, locus M5) Rattus norvegicus
Symbol: RT1-M5
Name: RT1 class Ib, locus M5
Description: Predicted to have peptide antigen binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to localize to the external side of plasma membrane and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; asthma (multiple); bone inflammation disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-C (major histocompatibility complex, class I, C); INTERACTS WITH 6-propyl-2-thiouracil; aflatoxin B1; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Hla-f; LOC499400; major histocompatibility complex, class I, F; RGD1560260; RT1 class Ib gene, locus M5; RT1 class Ib, locus M5 (mapped); RT1-M5_mapped; RT1.M5; similar to RT1 class I, M5
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0202,038,158 - 2,040,422 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,038,158 - 2,040,422 (-)Ensembl
Rnor_5.0204,078,537 - 4,080,801 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,638,276 - 1,640,540 (-)NCBIRGSC3.4rn4RGSC3.4
Celera202,254,856 - 2,257,120 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on RT1-M5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1595816
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.