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ONTOLOGY REPORT - ANNOTATIONS


Term:leukocyte mediated cytotoxicity
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Accession:GO:0001909 term browser browse the term
Definition:The directed killing of a target cell by a leukocyte.
Comment:Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system.
Synonyms:exact_synonym: immune cell mediated cell death;   immune cell mediated cell killing;   immune cell mediated cytotoxicity;   leucocyte mediated cytotoxicity
 only_in_taxon: NCBITaxon:7742 ! Vertebrata



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leukocyte mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:2661962 (MGI:3718167|PMID:17526748) RGD PMID:17526748 MGI:3718167 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Stxbp2 syntaxin binding protein 2 involved_in ISO (PMID:19884660) RGD PMID:19884660 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
JBrowse link
antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr1a Fc gamma receptor 1A acts_upstream_of_or_within
involved_in
ISO MGI:2664927|MGI:2679238 (MGI:2664488|PMID:11911824), (MGI:2679189|PMID:11911823)
(PMID:11711607)
RGD PMID:11711607 PMID:11911823 PMID:11911824 MGI:2664488 MGI:2679189 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (MGI:2683749|PMID:9743367), (MGI:82508|PMID:8769481) RGD PMID:8769481 PMID:9743367 MGI:2683749 MGI:82508 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:11711607), (PMID:27670158)
(PMID:11711607), (PMID:27670158), (PMID:28652325)
RGD PMID:11711607 PMID:27670158 PMID:28652325 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 acts_upstream_of_or_within
involved_in
ISO (MGI:2683749|PMID:9743367)
(PMID:11711607)
RGD PMID:9743367 PMID:11711607 MGI:2683749 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:24760828) RGD PMID:24760828 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:25786175), (PMID:28652325) RGD PMID:25786175 PMID:28652325 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608), (MGI:6810811|PMID:33911019) RGD PMID:32839608 PMID:33911019 MGI:6506882 MGI:6810811 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Unc13d unc-13 homolog D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3628822 (MGI:3703574|PMID:17420270)
Ensembl
RGD
PMID:17420270 GO_REF:0000107 MGI:3703574 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr12:16,728,477...16,764,261
Ensembl chr12:16,728,524...16,764,097
JBrowse link
natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISO
ISS
(PMID:24088571)
GO_REF:0000024
RGD
UniProt
PMID:24088571 GO_REF:0000024 NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596
JBrowse link
G Cd2 Cd2 molecule involved_in ISO (PMID:23006327) RGD PMID:23006327 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma involved_in ISS
ISO
GO_REF:0000024
(MGI:1350450|PMID:10587348)
UniProt
RGD
PMID:10587348 GO_REF:0000024 MGI:1350450 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:10318937)
(PMID:10318937), (PMID:23006327)
RGD PMID:10318937 PMID:23006327 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Gzmb granzyme B involved_in ISS
ISO
GO_REF:0000024
(PMID:21795594), (PMID:32188940)
UniProt
RGD
PMID:21795594 PMID:32188940 GO_REF:0000024 NCBI chr15:30,343,361...30,346,792
Ensembl chr15:30,173,603...30,346,814
JBrowse link
G Il18 interleukin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3578455|PMID:15843532)
Ensembl
RGD
PMID:15843532 GO_REF:0000107 MGI:3578455 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il21 interleukin 21 acts_upstream_of ISO (MGI:3028812|PMID:14764669) RGD PMID:14764669 MGI:3028812 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Kif5b kinesin family member 5B involved_in ISS
ISO
GO_REF:0000024
(PMID:24088571)
UniProt
RGD
PMID:24088571 GO_REF:0000024 NCBI chr17:51,489,873...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
G Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 involved_in ISO (PMID:18502829) RGD PMID:18502829 NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:163,032,938...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of ISO MGI:2176269 (MGI:80003|PMID:8602528) RGD PMID:8602528 MGI:80003 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404
JBrowse link
G Lyst lysosomal trafficking regulator involved_in ISO (PMID:10648412), (PMID:6154765) RGD PMID:6154765 PMID:10648412 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10426993) RGD PMID:10426993 NCBI chr 1:78,372,138...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608), (MGI:6810811|PMID:33911019) RGD PMID:32839608 PMID:33911019 MGI:6506882 MGI:6810811 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Plekhm2 pleckstrin homology and RUN domain containing M2 involved_in ISO (PMID:24088571) RGD PMID:24088571 NCBI chr 5:153,939,582...153,978,625
Ensembl chr 5:153,940,262...153,978,689
JBrowse link
G Prdx1 peroxiredoxin 1 acts_upstream_of_or_within ISO MGI:2670538 (MGI:2669020|PMID:12891360) RGD PMID:12891360 MGI:2669020 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856073 (MGI:54961|PMID:6971254)
Ensembl
RGD
PMID:6971254 GO_REF:0000107 MGI:54961 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Raet1e retinoic acid early transcript 1E involved_in ISO (PMID:15240696) RGD PMID:15240696 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
JBrowse link
G Raet1l retinoic acid early transcript 1L acts_upstream_of_or_within ISO (MGI:1860373|PMID:10894171) RGD PMID:10894171 MGI:1860373 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410
JBrowse link
G Rnf19b ring finger protein 19B acts_upstream_of_or_within ISO MGI:4436863 (MGI:4430768|PMID:19915045) RGD PMID:19915045 MGI:4430768 NCBI chr 5:141,406,085...141,431,380
Ensembl chr 5:141,406,118...141,431,380
JBrowse link
G Sh2d1a SH2 domain containing 1A acts_upstream_of ISO MGI:1349420|MGI:3575311|MGI:3622649 (MGI:3639618|PMID:16127454), (MGI:4355255|PMID:19648922) RGD PMID:16127454 PMID:19648922 MGI:3639618 MGI:4355255 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of ISO MGI:1328352|MGI:1349420|MGI:3641175 (MGI:3639618|PMID:16127454), (MGI:4355255|PMID:19648922) RGD PMID:16127454 PMID:19648922 MGI:3639618 MGI:4355255 NCBI chr13:82,416,362...82,461,511
Ensembl chr13:82,437,428...82,461,509
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of ISO MGI:1857249 (MGI:3655409|PMID:9841920) RGD PMID:9841920 MGI:3655409 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of
involved_in
ISO
IEA
MGI:2181592 (MGI:3655409|PMID:9841920)
GO_REF:0000107
RGD
Ensembl
PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080) RGD PMID:23042080 MGI:5460953 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Ulbp1 UL16 binding protein 1 involved_in ISO (PMID:11239445) RGD PMID:11239445 NCBI chr 1:1,694,255...1,716,160 JBrowse link
natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608) RGD PMID:32839608 MGI:6506882 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
negative regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3639805|PMID:16732273)
UniProt
RGD
PMID:16732273 GO_REF:0000024 MGI:3639805 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:18604210) RGD PMID:18604210 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Clec12b C-type lectin domain family 12, member B involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:18835194 RGD:11568650 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9021955 RGD:9685777 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
JBrowse link
G Igf2 insulin-like growth factor 2 IDA RGD PMID:9021955 RGD:9685777 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206), (PMID:9486650) RGD PMID:9485206 PMID:9486650 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
ISS
(PMID:9486650)
GO_REF:0000024
RGD
UniProt
PMID:9486650 GO_REF:0000024 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,138...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IMP RGD PMID:10837412 RGD:2313500 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:10190900), (PMID:12874224) RGD PMID:10190900 PMID:12874224 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:3641175 (MGI:3639618|PMID:16127454) RGD PMID:16127454 MGI:3639618 NCBI chr13:82,416,362...82,461,511
Ensembl chr13:82,437,428...82,461,509
JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:23696226)
(MGI:5512785|PMID:23696226)
GO_REF:0000024
RGD
UniProt
PMID:23696226 GO_REF:0000024 MGI:5512785 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,032,938...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (MGI:893318|PMID:9215624) RGD PMID:9215624 MGI:893318 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206) RGD PMID:9485206 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
ISS
(PMID:9485206)
GO_REF:0000024
RGD
UniProt
PMID:9485206 GO_REF:0000024 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta acts_upstream_of_or_within ISO MGI:2181294 (MGI:3772519|PMID:18097009) RGD PMID:18097009 MGI:3772519 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO
GO_REF:0000024
(MGI:3654612|PMID:9725213)
UniProt
RGD
PMID:9725213 GO_REF:0000024 MGI:3654612 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,229 JBrowse link
neutrophil-mediated killing of bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:104696 (MGI:6478086|PMID:22419116) RGD PMID:22419116 MGI:6478086 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:108005 (MGI:6478086|PMID:22419116)
Ensembl
RGD
PMID:22419116 GO_REF:0000107 MGI:6478086 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451
JBrowse link
neutrophil-mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed acts_upstream_of_or_within ISO MGI:2182177 (MGI:4353632|PMID:11907569) RGD PMID:11907569 MGI:4353632 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:3576788 (MGI:4353632|PMID:11907569) RGD PMID:11907569 MGI:4353632 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
neutrophil-mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed involved_in ISO (PMID:20421939) RGD PMID:20421939 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G F2 coagulation factor II involved_in IEA
ISO
GO_REF:0000107
(PMID:20421939)
Ensembl
RGD
PMID:20421939 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1930003 (MGI:5471912|PMID:23241959)
PMID:21873635
RGD PMID:23241959 PMID:21873635 MGI:5471912, RGD:13792537 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
JBrowse link
G Trem3 triggering receptor expressed on myeloid cells 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:12,749,821...12,762,547
Ensembl chr 9:12,749,852...12,760,779
JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO MGI:3706236 (MGI:5518492|PMID:24042119) RGD PMID:24042119 MGI:5518492 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056
JBrowse link
neutrophil-mediated killing of gram-positive bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsg cathepsin G acts_upstream_of_or_within ISO MGI:2182170 (MGI:4353632|PMID:11907569) RGD PMID:11907569 MGI:4353632 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:3576788 (MGI:4353632|PMID:11907569) RGD PMID:11907569 MGI:4353632 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within ISO (MGI:6453663|PMID:30248149) RGD PMID:30248149 MGI:6453663 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113
JBrowse link
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
positive regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:8103296 RGD:8549560 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M involved_in ISO (MGI:3812233|PMID:18685038) RGD PMID:18685038 MGI:3812233 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6093262|PMID:28628103) RGD PMID:28628103 MGI:6093262 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in IBA
ISO
PMID:21873635
(MGI:3812233|PMID:18685038)
RGD PMID:18685038 PMID:21873635 MGI:3812233, RGD:13792537 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,666...37,831,131
Ensembl chr19:37,744,633...37,829,167
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA
(PMID:23632890)
GO_REF:0000107
RGD
Ensembl
PMID:23632890 GO_REF:0000107 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,666...37,831,131
Ensembl chr19:37,744,633...37,829,167
JBrowse link
G Cadm1 cell adhesion molecule 1 involved_in ISO
ISS
(PMID:15811952)
(MGI:3689781|PMID:15811952)
GO_REF:0000024
RGD
HGNC
PMID:15811952 GO_REF:0000024 MGI:3689781 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:12486241), (PMID:17307798) RGD PMID:12486241 PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Cd226 CD226 molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)
RGD PMID:15811952 MGI:3689781 NCBI chr 8:41,340,117...41,377,343
Ensembl chr 8:41,340,837...41,377,343
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:2204066) RGD PMID:2204066 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il18rap interleukin 18 receptor accessory protein acts_upstream_of_or_within ISO MGI:3579137 (MGI:3578455|PMID:15843532) RGD PMID:15843532 MGI:3578455 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959
JBrowse link
G Il21 interleukin 21 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:18005035)
(MGI:3028812|PMID:14764669)
PMID:21873635
RGD PMID:14764669 PMID:18005035 PMID:21873635 MGI:3028812, RGD:13792537 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Klrb1c killer cell lectin like receptor B1C acts_upstream_of_or_within ISO (MGI:1336837|PMID:10229828), (MGI:1336838|PMID:10229823) RGD PMID:10229823 PMID:10229828 MGI:1336837 MGI:1336838 NCBI chr 4:162,380,773...162,394,688
Ensembl chr 4:162,381,602...162,393,786
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO
IBA
(PMID:9754572)
PMID:21873635
RGD PMID:9754572 PMID:21873635 RGD:13792537 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Klrc3 killer cell lectin like receptor C3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IBA
(PMID:9754572)
PMID:21873635
RGD PMID:9754572 PMID:21873635 RGD:13792537 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 involved_in ISO
IBA
(PMID:15294961)
PMID:21873635
RGD PMID:15294961 PMID:21873635 RGD:13792537 NCBI chr 4:163,032,938...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
G Klrh1 killer cell lectin-like receptor subfamily H, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,288,228...163,301,977
Ensembl chr 4:163,288,229...163,300,535
JBrowse link
G Klri1 killer cell lectin-like receptor family I member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870
JBrowse link
G Klri2 killer cell lectin-like receptor family I member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000002
(MGI:3054301|PMID:15294961)
(MGI:2450811|PMID:12645935)
GO_REF:0000107
(PMID:15294961)
PMID:21873635
UniProt
InterPro
RGD
Ensembl
PMID:12645935 PMID:15294961 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:2450811 MGI:3054301, RGD:13792537 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of_or_within ISO MGI:2176269 (MGI:80003|PMID:8602528) RGD PMID:8602528 MGI:80003 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like acts_upstream_of_or_within ISO MGI:3701255 (MGI:3700871|PMID:16476767) RGD PMID:16476767 MGI:3700871
G Ly49s3 Ly-49 stimulatory receptor 3 IDA RGD PMID:12077224 RGD:633264 Ensembl chr 4:164,122,072...164,341,692 JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO
IEA
IBA
(PMID:16304049)
GO_REF:0000002
PMID:21873635
RGD
InterPro
PMID:16304049 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Raet1e retinoic acid early transcript 1E involved_in ISO (PMID:18544572) RGD PMID:18544572 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
JBrowse link
G Raet1l retinoic acid early transcript 1L IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410
JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) RGD PMID:19933860 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:23335510) RGD PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within ISO MGI:3701255 (MGI:3700871|PMID:16476767) RGD PMID:16476767 MGI:3700871 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:23335510) RGD PMID:23335510 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Sh2d1a SH2 domain containing 1A acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1349420|MGI:3575311|MGI:3622649 (MGI:3639618|PMID:16127454), (MGI:4355255|PMID:19648922)
PMID:21873635
RGD PMID:16127454 PMID:19648922 PMID:21873635 MGI:3639618 MGI:4355255, RGD:13792537 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:1328352|MGI:1349420|MGI:98923 (MGI:4355255|PMID:19648922), (MGI:4839659|PMID:20962259) RGD PMID:19648922 PMID:20962259 MGI:4355255 MGI:4839659 NCBI chr13:82,416,362...82,461,511
Ensembl chr13:82,437,428...82,461,509
JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:16920955) RGD PMID:16920955 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:1857249 (MGI:3655409|PMID:9841920) RGD PMID:9841920 MGI:3655409 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181592 (MGI:3655409|PMID:9841920)
Ensembl
RGD
PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1349420|MGI:3622649 (MGI:4839659|PMID:20962259)
GO_REF:0000107
RGD
Ensembl
PMID:20962259 GO_REF:0000107 MGI:4839659 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IBA
ISO
PMID:21873635
(PMID:12913096)
RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in IBA
ISO
PMID:21873635
(MGI:3689781|PMID:15811952)
(PMID:15811952)
RGD PMID:15811952 PMID:21873635 MGI:3689781, RGD:13792537 NCBI chr 8:41,340,117...41,377,343
Ensembl chr 8:41,340,837...41,377,343
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IBA
ISO
PMID:21873635
(PMID:12913096)
RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656
JBrowse link
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:15546957) RGD PMID:15546957 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5586806|PMID:10725737)
Ensembl
RGD
PMID:10725737 GO_REF:0000107 MGI:5586806 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Pomc proopiomelanocortin involved_in ISO (PMID:10670585) RGD PMID:10670585 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:21501162) RGD PMID:21501162 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (MGI:3611636|PMID:16299293) RGD PMID:16299293 MGI:3611636 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2180705|PMID:10201995)
PMID:21873635
RGD PMID:10201995 PMID:21873635 MGI:2180705, RGD:13792537 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISO (MGI:5432330|PMID:22522492) RGD PMID:22522492 MGI:5432330 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686
JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO
GO_REF:0000024
(MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A IDA prevention of heat shock-induced resistance to CTL-mediated killing RGD PMID:10679071 RGD:1298959 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:8871636 RGD:10059395 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:1674604), (PMID:2204066) RGD PMID:1674604 PMID:2204066 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like acts_upstream_of_or_within ISO MGI:3701255 (MGI:3611636|PMID:16299293), (MGI:3700863|PMID:16461341), (MGI:3700871|PMID:16476767), (MGI:52901|PMID:8464890) RGD PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767 MGI:3611636 MGI:3700863 MGI:3700871 MGI:52901
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:3042190 (MGI:3040567|PMID:14761980) RGD PMID:14761980 MGI:3040567 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (MGI:55923|PMID:6233370) RGD PMID:6233370 MGI:55923 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 involved_in IDA
ISO
(PMID:2420472) RGD PMID:2420472 PMID:11773898 RGD:2313503 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 acts_upstream_of_or_within
involved_in
ISO (MGI:50291|PMID:1538753)
(PMID:25631937)
RGD PMID:1538753 PMID:25631937 MGI:50291 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:23851683) RGD PMID:23851683 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within ISO MGI:3701255 (MGI:3611636|PMID:16299293), (MGI:3700863|PMID:16461341), (MGI:3700871|PMID:16476767), (MGI:52901|PMID:8464890) RGD PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767 MGI:3611636 MGI:3700863 MGI:3700871 MGI:52901 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in
acts_upstream_of_or_within
ISO (PMID:25631937)
(MGI:50291|PMID:1538753)
RGD PMID:1538753 PMID:25631937 MGI:50291 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Stx7 syntaxin 7 involved_in ISO
IEA
(PMID:21438968)
GO_REF:0000107
RGD
Ensembl
PMID:21438968 GO_REF:0000107 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in
ISO
IEA
IDA
(MGI:3611636|PMID:16299293), (MGI:50291|PMID:1538753)
GO_REF:0000107
PMID:1758495
RGD
Ensembl
PMID:1538753 PMID:16299293 PMID:1758495 GO_REF:0000107 MGI:3611636 MGI:50291, RGD:1299069 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329
JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA
(PMID:31959982)
GO_REF:0000107
RGD
Ensembl
PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Slc22a13l1 solute carrier family 22 member 13-like 1 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,958,209...118,972,614
Ensembl chr 8:118,961,000...118,966,046
JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO MGI:107539 (MGI:2682492|PMID:12858173), (MGI:3041277|PMID:14990792), (MGI:3849756|PMID:19535641) RGD PMID:12858173 PMID:14990792 PMID:19535641 MGI:2682492 MGI:3041277 MGI:3849756 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 involved_in ISO (PMID:18502829), (PMID:2784569), (PMID:8046333) RGD PMID:2784569 PMID:8046333 PMID:18502829 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:21857942) RGD PMID:21857942 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc gamma receptor 2A IMP RGD PMID:16482158 RGD:2293335 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klrb1 killer cell lectin like receptor B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:162,456,294...162,474,989
Ensembl chr 4:162,456,294...162,474,989
JBrowse link
G Klrb1a killer cell lectin like receptor B1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675
JBrowse link
G Klrb1b killer cell lectin-like receptor subfamily B member 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:161,949,061...161,961,505
Ensembl chr 4:161,890,577...161,961,675
JBrowse link
G Klrb1c killer cell lectin like receptor B1C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:162,380,773...162,394,688
Ensembl chr 4:162,381,602...162,393,786
JBrowse link
G Lep leptin involved_in ISS
ISO
GO_REF:0000024
(PMID:12504075)
UniProt
RGD
PMID:12504075 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Nkr-p1c killer cell lectin-like receptor subfamily B member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 involved_in ISO (PMID:11062502) RGD PMID:11062502 NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243
JBrowse link
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase1 deoxyribonuclease 1 involved_in ISS
ISO
PMID:29191910
(MGI:6094744|PMID:29191910)
RGD PMID:29191910 PMID:29191910 MGI:6094744, RGD:13464261 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 involved_in ISS
ISO
PMID:29191910
(MGI:6094744|PMID:29191910)
RGD PMID:29191910 PMID:29191910 MGI:6094744, RGD:13464261 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
JBrowse link
regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl6 C-X-C motif chemokine ligand 6 acts_upstream_of_or_within ISO MGI:4819800 (MGI:4819434|PMID:20643340) RGD PMID:20643340 MGI:4819434 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO (PMID:22473704) RGD PMID:22473704 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q61160 (MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadm1 cell adhesion molecule 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:3689781|PMID:15811952)
(PMID:15811952)
HGNC
RGD
PMID:15811952 PMID:21873635 GO_REF:0000024 MGI:3689781, RGD:13792537 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:12913096)
PMID:21873635
RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (MGI:2450811|PMID:12645935) RGD PMID:12645935 MGI:2450811 NCBI chr 1:1,694,255...1,716,160 JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nectin2 nectin cell adhesion molecule 2 involved_in IBA
ISO
PMID:21873635
(PMID:15039383)
RGD PMID:15039383 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:15039383) RGD PMID:15039383 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin acts_upstream_of ISO (MGI:3611636|PMID:16299293) RGD PMID:16299293 MGI:3611636 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cadm1 cell adhesion molecule 1 NOT|involved_in ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule NOT|involved_in ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:41,340,117...41,377,343
Ensembl chr 8:41,340,837...41,377,343
JBrowse link
G Ctsc cathepsin C involved_in ISO UniProtKB:P49935 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsh cathepsin H involved_in ISS
ISO
GO_REF:0000024
UniProtKB:P97821 (MGI:4838939|PMID:20435891)
UniProt
RGD
PMID:20435891 GO_REF:0000024 MGI:4838939 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 acts_upstream_of_or_within ISO MGI:4359722 (MGI:7294920|PMID:35482418) RGD PMID:35482418 MGI:7294920 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5605955|PMID:12763482)
UniProt
RGD
PMID:12763482 GO_REF:0000024 MGI:5605955 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733
JBrowse link
G Gfus GDP-L-fucose synthase acts_upstream_of_or_within ISO (MGI:58355|PMID:2568889) RGD PMID:2568889 MGI:58355 NCBI chr 7:107,612,087...107,617,005
Ensembl chr 7:107,612,094...107,616,948
JBrowse link
G Gzmb granzyme B acts_upstream_of_or_within ISO MGI:1857156 (MGI:3665503|PMID:16618603) RGD PMID:16618603 MGI:3665503 NCBI chr15:30,343,361...30,346,792
Ensembl chr15:30,173,603...30,346,814
JBrowse link
G Gzmm granzyme M involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3531039|PMID:15454490)
Ensembl
RGD
PMID:15454490 GO_REF:0000107 MGI:3531039 NCBI chr 7:10,011,065...10,016,841
Ensembl chr 7:10,011,066...10,016,665
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 acts_upstream_of_or_within ISO MGI:1857299 (MGI:2675193|PMID:12944494) RGD PMID:12944494 MGI:2675193 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of ISO MGI:1857198 (MGI:893318|PMID:9215624) RGD PMID:9215624 MGI:893318 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10426993) RGD PMID:10426993 NCBI chr 1:78,372,138...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of ISO MGI:3042190 (MGI:3040567|PMID:14761980) RGD PMID:14761980 MGI:3040567 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta acts_upstream_of ISO MGI:2181294 (MGI:3772519|PMID:18097009) RGD PMID:18097009 MGI:3772519 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Prf1 perforin 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3531039|PMID:15454490)
(MGI:5285144|PMID:21037563), (MGI:6830380|PMID:26306037)
PMID:21873635
RGD PMID:15454490 PMID:21037563 PMID:26306037 PMID:21873635 MGI:3531039 MGI:5285144 MGI:6830380, RGD:13792537 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Raet1e retinoic acid early transcript 1E acts_upstream_of_or_within ISO (MGI:3037535|PMID:11567106) RGD PMID:11567106 MGI:3037535 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 acts_upstream_of ISO (MGI:50291|PMID:1538753) RGD PMID:1538753 MGI:50291 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 acts_upstream_of ISO (MGI:50291|PMID:1538753) RGD PMID:1538753 MGI:50291 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Serpinb9 serpin family B member 9 acts_upstream_of_or_within ISO MGI:3687210 (MGI:3665503|PMID:16618603) RGD PMID:16618603 MGI:3665503 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080) RGD PMID:23042080 MGI:5460953 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of
involved_in
ISO
IEA
(MGI:3611636|PMID:16299293), (MGI:50291|PMID:1538753)
GO_REF:0000107
RGD
Ensembl
PMID:1538753 PMID:16299293 GO_REF:0000107 MGI:3611636 MGI:50291 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    cellular process 18295
      cell killing 228
        leukocyte mediated cytotoxicity 140
          T cell mediated cytotoxicity + 51
          antibody-dependent cellular cytotoxicity + 6
          microglial cell mediated cytotoxicity + 5
          natural killer cell mediated cytotoxicity + 84
          negative regulation of leukocyte mediated cytotoxicity + 30
          neutrophil mediated cytotoxicity + 17
          positive regulation of leukocyte mediated cytotoxicity + 68
          regulation of leukocyte mediated cytotoxicity + 99
Path 2
Term Annotations click to browse term
  biological_process 19898
    immune system process 2579
      immune effector process 687
        leukocyte mediated immunity 448
          leukocyte mediated cytotoxicity 140
            T cell mediated cytotoxicity + 51
            antibody-dependent cellular cytotoxicity + 6
            microglial cell mediated cytotoxicity + 5
            natural killer cell mediated cytotoxicity + 84
            negative regulation of leukocyte mediated cytotoxicity + 30
            neutrophil mediated cytotoxicity + 17
            positive regulation of leukocyte mediated cytotoxicity + 68
            regulation of leukocyte mediated cytotoxicity + 99
paths to the root