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ONTOLOGY REPORT - ANNOTATIONS


Term:leukocyte mediated cytotoxicity
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Accession:GO:0001909 term browser browse the term
Definition:The directed killing of a target cell by a leukocyte.
Comment:Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system.
Synonyms:exact_synonym: immune cell mediated cell death;   immune cell mediated cell killing;   immune cell mediated cytotoxicity;   leucocyte mediated cytotoxicity


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leukocyte mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 ISO MGI:2661962 (MGI:3718167|PMID:17526748) RGD PMID:17526748 MGI:3718167 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Stxbp2 syntaxin binding protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19884660)
Ensembl
RGD
PMID:19884660 GO_REF:0000107 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175
JBrowse link
antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr1a Fc fragment of IgG receptor Ia ISO MGI:2664927|MGI:2679238 (MGI:2664488|PMID:11911824), (MGI:2679189|PMID:11911823) RGD PMID:11911823 PMID:11911824 MGI:2664488 MGI:2679189 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO MGI:1861924 (MGI:2683749|PMID:9743367), (MGI:82508|PMID:8769481) RGD PMID:8769481 PMID:9743367 MGI:2683749 MGI:82508 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 ISO (MGI:2683749|PMID:9743367) RGD PMID:9743367 MGI:2683749 NCBI chr 6:139,140,572...139,784,388
Ensembl chr 6:139,140,679...139,142,218
JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:79,722,334...79,776,228
Ensembl chr 8:79,722,334...79,776,221
JBrowse link
G Stx11 syntaxin 11 ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:24760828) RGD PMID:24760828 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Rab27a RAB27A, member RAS oncogene family ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:79,722,334...79,776,228
Ensembl chr 8:79,722,334...79,776,221
JBrowse link
G Stx11 syntaxin 11 ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
G Unc13d unc-13 homolog D involved_in ISO
IEA
MGI:3628822 (MGI:3703574|PMID:17420270)
GO_REF:0000107
RGD
Ensembl
PMID:17420270 GO_REF:0000107 MGI:3703574 NCBI chr10:104,613,907...104,628,664
Ensembl chr10:104,613,928...104,628,676
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT
NOT|involved_in
ISO (PMID:18042464) RGD PMID:18042464 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07028902.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr17:90,370,882...90,522,091 JBrowse link
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISO (PMID:24088571) RGD PMID:24088571 NCBI chr 4:140,837,745...140,881,866
Ensembl chr 4:140,837,745...140,881,865
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma involved_in ISS
ISO
GO_REF:0000024
(MGI:1350450|PMID:10587348)
UniProt
RGD
PMID:10587348 GO_REF:0000024 MGI:1350450 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656
JBrowse link
G Gzmb granzyme B involved_in ISO
ISS
(PMID:21795594), (PMID:32188940)
GO_REF:0000024
RGD
UniProt
PMID:21795594 PMID:32188940 GO_REF:0000024 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Gzmbl2 Granzyme B-like 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr15:36,469,318...36,472,393
Ensembl chr15:35,413,793...35,417,316
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Il18 interleukin 18 IEA
ISO
GO_REF:0000107
(MGI:3578455|PMID:15843532)
Ensembl
RGD
PMID:15843532 GO_REF:0000107 MGI:3578455 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Kif5b kinesin family member 5B involved_in ISS
ISO
GO_REF:0000024
(PMID:24088571)
UniProt
RGD
PMID:24088571 GO_REF:0000024 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
JBrowse link
G Kir3dl1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 involved_in ISO (PMID:18502829) RGD PMID:18502829 NCBI chr 1:73,306,564...73,345,009
Ensembl chr 1:73,307,569...73,344,955
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:163,346,684...163,355,050
Ensembl chr 4:163,349,125...163,354,976
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17562706)
Ensembl
RGD
PMID:17562706 GO_REF:0000107 NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
JBrowse link
G Lyst lysosomal trafficking regulator involved_in ISO (PMID:10648412), (PMID:6154765) RGD PMID:6154765 PMID:10648412 NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10426993) RGD PMID:10426993 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G Plekhm2 pleckstrin homology and RUN domain containing M2 involved_in IEA
ISO
GO_REF:0000107
(PMID:24088571)
Ensembl
RGD
PMID:24088571 GO_REF:0000107 NCBI chr 5:160,182,556...160,219,770
Ensembl chr 5:160,182,251...160,219,812
JBrowse link
G Prdx1 peroxiredoxin 1 ISO MGI:2670538 (MGI:2669020|PMID:12891360) RGD PMID:12891360 MGI:2669020 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in IEA
ISO
GO_REF:0000107
MGI:1856073 (MGI:54961|PMID:6971254)
Ensembl
RGD
PMID:6971254 GO_REF:0000107 MGI:54961 NCBI chr 4:157,239,141...157,263,890
Ensembl chr 4:157,239,142...157,263,890
JBrowse link
G Raet1e retinoic acid early transcript 1E involved_in ISO (PMID:15240696) RGD PMID:15240696 NCBI chr 1:1,101,666...1,120,340
Ensembl chr 1:1,101,965...1,116,926
JBrowse link
G Rnf19b ring finger protein 19B ISO MGI:4436863 (MGI:4430768|PMID:19915045) RGD PMID:19915045 MGI:4430768 NCBI chr 5:147,246,032...147,270,892
Ensembl chr 5:147,246,037...147,270,957
JBrowse link
G Stx11 syntaxin 11 ISO MGI:5461477 (MGI:5460953|PMID:23042080) RGD PMID:23042080 MGI:5460953 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
G Ulbp1 UL16 binding protein 1 involved_in ISO (PMID:11239445) RGD PMID:11239445 NCBI chr 1:1,181,301...1,200,526
Ensembl chr 1:1,180,932...1,220,916
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:18604210) RGD PMID:18604210 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Clec12b C-type lectin domain family 12, member B involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:163,140,883...163,157,996
Ensembl chr 4:163,141,132...163,157,744
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:18835194 RGD:11568650 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9021955 RGD:9685777 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Igf2 insulin-like growth factor 2 IDA RGD PMID:9021955 RGD:9685777 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206), (PMID:9486650) RGD PMID:9485206 PMID:9486650 NCBI chr 4:163,453,435...163,463,718
Ensembl chr 4:163,458,528...163,463,718
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
ISS
(PMID:9486650)
GO_REF:0000024
RGD
UniProt
PMID:9486650 GO_REF:0000024 NCBI chr 4:163,358,355...163,369,925
Ensembl chr 4:163,358,009...163,369,854
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IMP RGD PMID:10837412 RGD:2313500 NCBI chr20:5,414,463...5,418,012
Ensembl chr20:5,351,605...5,421,098
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 ISO MGI:3641175 (MGI:3639618|PMID:16127454) RGD PMID:16127454 MGI:3639618 NCBI chr13:88,557,361...88,584,078
Ensembl chr13:88,557,860...88,577,691
JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:23696226)
GO_REF:0000024
(MGI:5512785|PMID:23696226)
RGD
UniProt
PMID:23696226 GO_REF:0000024 MGI:5512785 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,346,684...163,355,050
Ensembl chr 4:163,349,125...163,354,976
JBrowse link
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Il7r interleukin 7 receptor ISO MGI:1857198 (MGI:893318|PMID:9215624) RGD PMID:9215624 MGI:893318
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206) RGD PMID:9485206 NCBI chr 4:163,453,435...163,463,718
Ensembl chr 4:163,458,528...163,463,718
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
ISS
(PMID:9485206)
GO_REF:0000024
RGD
UniProt
PMID:9485206 GO_REF:0000024 NCBI chr 4:163,358,355...163,369,925
Ensembl chr 4:163,358,009...163,369,854
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in IEA
ISO
GO_REF:0000107
MGI:2181294 (MGI:3772519|PMID:18097009)
Ensembl
RGD
PMID:18097009 GO_REF:0000107 MGI:3772519 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO
GO_REF:0000024
(MGI:3654612|PMID:9725213)
UniProt
RGD
PMID:9725213 GO_REF:0000024 MGI:3654612 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
neutrophil-mediated killing of bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor ISO MGI:104696 (MGI:6478086|PMID:22419116) RGD PMID:22419116 MGI:6478086 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in ISO
IEA
MGI:108005 (MGI:6478086|PMID:22419116)
GO_REF:0000107
RGD
Ensembl
PMID:22419116 GO_REF:0000107 MGI:6478086 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
neutrophil-mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed ISO MGI:2182177 (MGI:4353632|PMID:11907569) RGD PMID:11907569 MGI:4353632 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO MGI:3576788 (MGI:4353632|PMID:11907569) RGD PMID:11907569 MGI:4353632 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
neutrophil-mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed involved_in ISO (PMID:20421939) RGD PMID:20421939 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G F2 coagulation factor II involved_in IEA
ISO
GO_REF:0000107
(PMID:20421939)
Ensembl
RGD
PMID:20421939 GO_REF:0000107 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ISO MGI:1930003 (MGI:5471912|PMID:23241959) RGD PMID:23241959 MGI:5471912 NCBI chr 9:14,727,887...14,743,371
Ensembl chr 9:14,727,976...14,809,447
JBrowse link
G Trem3 triggering receptor expressed on myeloid cells 3 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:14,713,935...14,725,945
Ensembl chr 9:14,713,935...14,724,093
JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator ISO MGI:3706236 (MGI:5518492|PMID:24042119) RGD PMID:24042119 MGI:5518492 NCBI chr 8:116,318,963...116,322,181
Ensembl chr 8:116,318,963...116,322,181
JBrowse link
neutrophil-mediated killing of gram-positive bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsg cathepsin G involved_in IEA
ISO
GO_REF:0000107
MGI:2182170 (MGI:4353632|PMID:11907569)
Ensembl
RGD
PMID:11907569 GO_REF:0000107 MGI:4353632 NCBI chr15:35,107,333...35,113,678
Ensembl chr15:35,111,091...35,113,678
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO MGI:3576788 (MGI:4353632|PMID:11907569) RGD PMID:11907569 MGI:4353632 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
positive regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:8103296 RGD:8549560 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M ISO (MGI:3812233|PMID:18685038) RGD PMID:18685038 MGI:3812233 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Stap1 signal transducing adaptor family member 1 ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:23,575,400...23,604,984
Ensembl chr14:23,576,085...23,604,834
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IBA
(MGI:3812233|PMID:18685038)
PMID:21873635
RGD PMID:18685038, PMID:21873635, PMID:21873635 MGI:3812233, RGD:13792537, RGD:13792537 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:41,805,252...41,860,076 JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:198,933,681...198,965,380
Ensembl chr 2:198,935,133...198,942,732
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:163,433,993...163,445,136
Ensembl chr 4:163,416,351...163,445,302
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:41,805,252...41,860,076 JBrowse link
G Cadm1 cell adhesion molecule 1 involved_in ISO
ISS
(PMID:15811952)
GO_REF:0000024
(MGI:3689781|PMID:15811952)
RGD
UniProt
PMID:15811952 GO_REF:0000024 MGI:3689781 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:12486241), (PMID:17307798) RGD PMID:12486241 PMID:17307798 NCBI chr 2:198,933,681...198,965,380
Ensembl chr 2:198,935,133...198,942,732
JBrowse link
G Cd226 CD226 molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)
RGD PMID:15811952 MGI:3689781 NCBI chr 8:45,152,584...45,216,082
Ensembl chr 8:45,153,308...45,215,974
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:78,377,228...78,386,683
Ensembl chr 4:78,378,144...78,385,577
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:2204066) RGD PMID:2204066 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO MGI:3579137 (MGI:3578455|PMID:15843532) RGD PMID:15843532 MGI:3578455 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il21 interleukin 21 involved_in ISO
IBA
(PMID:18005035)
PMID:21873635
(MGI:3028812|PMID:14764669)
RGD PMID:14764669 PMID:18005035, PMID:21873635, PMID:21873635 MGI:3028812, RGD:13792537, RGD:13792537 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356
JBrowse link
G Klrb1c killer cell lectin like receptor B1C ISO (MGI:1336837|PMID:10229828), (MGI:1336838|PMID:10229823) RGD PMID:10229823 PMID:10229828 MGI:1336837 MGI:1336838 NCBI chr 4:162,528,614...162,553,421
Ensembl chr 4:162,541,751...162,553,705
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:9754572) RGD PMID:9754572 NCBI chr 4:163,433,993...163,445,136
Ensembl chr 4:163,416,351...163,445,302
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IEA
(PMID:9754572)
GO_REF:0000107
RGD
Ensembl
PMID:9754572 GO_REF:0000107 NCBI chr 4:163,358,355...163,369,925
Ensembl chr 4:163,358,009...163,369,854
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 involved_in ISO (PMID:15294961) RGD PMID:15294961 NCBI chr 4:163,346,684...163,355,050
Ensembl chr 4:163,349,125...163,354,976
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(PMID:15294961)
PMID:21873635
GO_REF:0000024
(MGI:2450811|PMID:12645935), (MGI:3054301|PMID:15294961)
Ensembl
RGD
UniProt
PMID:12645935 PMID:15294961, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2450811 MGI:3054301, RGD:13792537, RGD:13792537 NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
JBrowse link
G Lag3 lymphocyte activating 3 ISO MGI:2176269 (MGI:80003|PMID:8602528) RGD PMID:8602528 MGI:80003 NCBI chr 4:157,425,644...157,433,700
Ensembl chr 4:157,425,644...157,433,467
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like ISO MGI:3701255 (MGI:3700871|PMID:16476767) RGD PMID:16476767 MGI:3700871 NCBI chr20:3,242,236...3,253,995
Ensembl chr20:3,242,470...3,249,189
JBrowse link
G Ly49s3 Ly-49 stimulatory receptor 3 IDA RGD PMID:12077224 RGD:633264 Ensembl chr 4:164,470,397...164,900,857 JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO
IEA
IBA
(PMID:16304049)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:16304049, PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr20:5,170,169...5,175,773
Ensembl chr20:5,170,215...5,175,773
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:80,820,306...80,835,712
Ensembl chr 1:80,820,050...80,835,701
JBrowse link
G Raet1e retinoic acid early transcript 1E involved_in ISO (PMID:18544572) RGD PMID:18544572 NCBI chr 1:1,101,666...1,120,340
Ensembl chr 1:1,101,965...1,116,926
JBrowse link
G Raet1l retinoic acid early transcript 1L IDA RGD PMID:20306467 RGD:9685184 NCBI chr 7:114,233,896...114,234,243 JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) RGD PMID:19933860 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Rrlt similar to retinoic acid early transcript 1L IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,437,716...1,442,089 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:1,814,661...1,833,033
Ensembl chr20:1,814,661...1,818,800
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:23335510) RGD PMID:23335510 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sh2d1a SH2 domain containing 1A ISO MGI:1349420|MGI:3575311|MGI:3622649 (MGI:3639618|PMID:16127454), (MGI:4355255|PMID:19648922) RGD PMID:16127454 PMID:19648922 MGI:3639618 MGI:4355255 NCBI chr  X:128,897,053...128,925,408
Ensembl chr  X:128,897,181...128,925,407
JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 ISO MGI:1328352|MGI:1349420|MGI:98923 (MGI:4355255|PMID:19648922), (MGI:4839659|PMID:20962259) RGD PMID:19648922 PMID:20962259 MGI:4355255 MGI:4839659 NCBI chr13:88,557,361...88,584,078
Ensembl chr13:88,557,860...88,577,691
JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:16920955) RGD PMID:16920955 NCBI chr13:90,300,160...90,321,781
Ensembl chr13:90,301,006...90,322,457
JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO MGI:1857249 (MGI:3655409|PMID:9841920) RGD PMID:9841920 MGI:3655409 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in IEA
ISO
GO_REF:0000107
MGI:2181592 (MGI:3655409|PMID:9841920)
Ensembl
RGD
PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 involved_in IEA
ISO
GO_REF:0000107
MGI:1349420|MGI:3622649 (MGI:4839659|PMID:20962259)
Ensembl
RGD
PMID:20962259 GO_REF:0000107 MGI:4839659 NCBI chr 9:9,617,551...9,675,167
Ensembl chr 9:9,617,786...9,675,110
JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032888.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr18:87,415,531...87,415,884 JBrowse link
G Cd226 CD226 molecule involved_in ISO
IBA
(PMID:12913096)
PMID:21873635
RGD PMID:12913096, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IBA
(PMID:15811952)
PMID:21873635
(MGI:3689781|PMID:15811952)
RGD PMID:15811952, PMID:21873635, PMID:21873635 MGI:3689781, RGD:13792537, RGD:13792537 NCBI chr 8:45,152,584...45,216,082
Ensembl chr 8:45,153,308...45,215,974
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:12913096)
PMID:21873635
RGD PMID:12913096, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:80,820,306...80,835,712
Ensembl chr 1:80,820,050...80,835,701
JBrowse link
G Rrlt similar to retinoic acid early transcript 1L IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,437,716...1,442,089 JBrowse link
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:15546957) RGD PMID:15546957 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5586806|PMID:10725737)
Ensembl
RGD
PMID:10725737 GO_REF:0000107 MGI:5586806 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Pomc proopiomelanocortin involved_in ISO (PMID:10670585) RGD PMID:10670585 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:21501162) RGD PMID:21501162 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin ISO (MGI:3611636|PMID:16299293) RGD PMID:16299293 MGI:3611636 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Cd1d1 CD1d1 molecule involved_in ISO
IBA
(MGI:2180705|PMID:10201995)
PMID:21873635
RGD PMID:10201995, PMID:21873635, PMID:21873635 MGI:2180705, RGD:13792537, RGD:13792537 NCBI chr 2:186,330,298...186,333,805
Ensembl chr 2:186,330,298...186,333,805
JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISS
ISO
GO_REF:0000024
(MGI:5432330|PMID:22522492)
UniProt
RGD
PMID:22522492 GO_REF:0000024 MGI:5432330 NCBI chr 7:104,514,566...104,641,875
Ensembl chr 7:104,516,391...104,556,419
JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO
GO_REF:0000024
(MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IDA prevention of heat shock-induced resistance to CTL-mediated killing RGD PMID:10679071 RGD:1298959 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:8871636 RGD:10059395 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:1674604), (PMID:2204066) RGD PMID:1674604 PMID:2204066 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il23a interleukin 23 subunit alpha ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like involved_in ISO (PMID:22031944), (PMID:2420472), (PMID:25631937), (PMID:8805302) RGD PMID:2420472 PMID:8805302 PMID:22031944 PMID:25631937 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like ISO MGI:3701255 (MGI:3611636|PMID:16299293), (MGI:3700863|PMID:16461341), (MGI:3700871|PMID:16476767), (MGI:52901|PMID:8464890) RGD PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767 MGI:3611636 MGI:3700863 MGI:3700871 MGI:52901 NCBI chr20:3,242,236...3,253,995
Ensembl chr20:3,242,470...3,249,189
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO MGI:3042190 (MGI:3040567|PMID:14761980) RGD PMID:14761980 MGI:3040567 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO (MGI:55923|PMID:6233370) RGD PMID:6233370 MGI:55923 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IDA RGD PMID:11773898 RGD:2313503 NCBI chr20:5,414,463...5,418,012
Ensembl chr20:5,351,605...5,421,098
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 ISO (MGI:50291|PMID:1538753) RGD PMID:1538753 MGI:50291 NCBI chr20:5,374,990...5,378,536
Ensembl chr20:5,374,985...5,378,539
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:23851683) RGD PMID:23851683 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO
IEA
(PMID:29884618)
GO_REF:0000107
RGD
Ensembl
PMID:29884618 GO_REF:0000107 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:1,814,661...1,833,033
Ensembl chr20:1,814,661...1,818,800
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:25631937)
(MGI:50291|PMID:1538753)
RGD PMID:1538753 PMID:25631937 MGI:50291 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Stx7 syntaxin 7 involved_in ISO (PMID:21438968) RGD PMID:21438968 NCBI chr 1:22,241,655...22,281,850
Ensembl chr 1:22,241,661...22,281,788
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member involved_in IDA
ISO
PMID:1758495
(MGI:3611636|PMID:16299293), (MGI:50291|PMID:1538753)
RGD PMID:1538753 PMID:16299293, PMID:1758495, PMID:1758495 MGI:3611636 MGI:50291, RGD:1299069, RGD:1299069 NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC685081 similar to solute carrier family 22 (organic cation transporter), member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:127,905,478...127,914,897
Ensembl chr 8:127,909,147...127,912,860
JBrowse link
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA
(PMID:31959982)
GO_REF:0000107
RGD
Ensembl
PMID:31959982 GO_REF:0000107 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec2d C-type lectin domain family 2, member D ISO MGI:107539 (MGI:2682492|PMID:12858173), (MGI:3041277|PMID:14990792), (MGI:3849756|PMID:19535641) RGD PMID:12858173 PMID:14990792 PMID:19535641 MGI:2682492 MGI:3041277 MGI:3849756 NCBI chr 4:162,278,252...162,302,881
Ensembl chr 4:162,292,305...162,302,156
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like NOT
NOT|involved_in
ISO (PMID:18502829)
(PMID:18502829), (PMID:8839770)
RGD PMID:8839770 PMID:18502829 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:21857942) RGD PMID:21857942 NCBI chr13:27,153,500...27,159,319
Ensembl chr13:27,153,925...27,158,628
JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587
JBrowse link
regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc fragment of IgG receptor IIa IMP RGD PMID:16482158 RGD:2293335 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lep leptin involved_in ISO
ISS
(PMID:12504075)
GO_REF:0000024
RGD
UniProt
PMID:12504075 GO_REF:0000024 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 involved_in ISO (PMID:11062502) RGD PMID:11062502 NCBI chr10:55,085,269...55,135,069
Ensembl chr10:55,085,259...55,135,092
JBrowse link
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase1 deoxyribonuclease 1 involved_in ISS
ISO
PMID:29191910
(MGI:6094744|PMID:29191910)
RGD PMID:29191910, PMID:29191910, PMID:29191910 MGI:6094744, RGD:13464261, RGD:13464261 NCBI chr10:11,757,681...11,760,672
Ensembl chr10:11,757,682...11,760,620
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 involved_in ISS
ISO
PMID:29191910
(MGI:6094744|PMID:29191910)
RGD PMID:29191910, PMID:29191910, PMID:29191910 MGI:6094744, RGD:13464261, RGD:13464261 NCBI chr15:18,710,492...18,736,476
Ensembl chr15:18,710,492...18,736,473
JBrowse link
regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl6 C-X-C motif chemokine ligand 6 ISO MGI:4819800 (MGI:4819434|PMID:20643340) RGD PMID:20643340 MGI:4819434 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in IEA
ISO
GO_REF:0000107
(PMID:22473704)
Ensembl
RGD
PMID:22473704 GO_REF:0000107 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q61160 (MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741
JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadm1 cell adhesion molecule 1 involved_in ISO
IBA
ISS
(PMID:15811952)
PMID:21873635
GO_REF:0000024
(MGI:3689781|PMID:15811952)
RGD
UniProt
PMID:15811952, PMID:21873635, PMID:21873635 GO_REF:0000024 MGI:3689781, RGD:13792537, RGD:13792537 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:12913096)
PMID:21873635
RGD PMID:12913096, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:80,820,306...80,835,712
Ensembl chr 1:80,820,050...80,835,701
JBrowse link
G Ulbp1 UL16 binding protein 1 ISO (MGI:2450811|PMID:12645935) RGD PMID:12645935 MGI:2450811 NCBI chr 1:1,181,301...1,200,526
Ensembl chr 1:1,180,932...1,220,916
JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:15039383)
PMID:21873635
RGD PMID:15039383, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:15039383) RGD PMID:15039383 NCBI chr 1:80,820,306...80,835,712
Ensembl chr 1:80,820,050...80,835,701
JBrowse link
T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadm1 cell adhesion molecule 1 NOT
NOT|involved_in
ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule NOT
NOT|involved_in
ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:45,152,584...45,216,082
Ensembl chr 8:45,153,308...45,215,974
JBrowse link
G Ctsc cathepsin C ISO UniProtKB:P49935 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctsh cathepsin H involved_in ISS
ISO
GO_REF:0000024
UniProtKB:P97821 (MGI:4838939|PMID:20435891)
UniProt
RGD
PMID:20435891 GO_REF:0000024 MGI:4838939 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5605955|PMID:12763482)
UniProt
RGD
PMID:12763482 GO_REF:0000024 MGI:5605955 NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839
JBrowse link
G Gfus GDP-L-fucose synthase ISO (MGI:58355|PMID:2568889) RGD PMID:2568889 MGI:58355 NCBI chr 7:116,958,427...116,963,281
Ensembl chr 7:116,958,392...116,963,295
JBrowse link
G Gzmb granzyme B ISO MGI:1857156 (MGI:3665503|PMID:16618603) RGD PMID:16618603 MGI:3665503 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Gzmm granzyme M involved_in IEA
ISO
GO_REF:0000107
(MGI:3531039|PMID:15454490)
Ensembl
RGD
PMID:15454490 GO_REF:0000107 MGI:3531039 NCBI chr 7:12,893,431...12,899,004
Ensembl chr 7:12,893,432...12,899,004
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO MGI:1857299 (MGI:2675193|PMID:12944494) RGD PMID:12944494 MGI:2675193 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like involved_in ISO (PMID:7504010) RGD PMID:7504010 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10426993) RGD PMID:10426993 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G Prf1 perforin 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3531039|PMID:15454490)
Ensembl
RGD
PMID:15454490 GO_REF:0000107 MGI:3531039 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Raet1e retinoic acid early transcript 1E ISO (MGI:3037535|PMID:11567106) RGD PMID:11567106 MGI:3037535 NCBI chr 1:1,101,666...1,120,340
Ensembl chr 1:1,101,965...1,116,926
JBrowse link
G Serpinb9 serpin family B member 9 ISO MGI:3687210 (MGI:3665503|PMID:16618603) RGD PMID:16618603 MGI:3665503 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865
JBrowse link
G Stx11 syntaxin 11 ISO MGI:5461477 (MGI:5460953|PMID:23042080) RGD PMID:23042080 MGI:5460953 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100364500 RT1 class I, locus CE11-like involved_in ISO (PMID:1402688), (PMID:17189421), (PMID:20364150) RGD PMID:1402688 PMID:17189421 PMID:20364150 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    cellular process 18896
      cell killing 222
        leukocyte mediated cytotoxicity 127
          T cell mediated cytotoxicity + 50
          antibody-dependent cellular cytotoxicity + 4
          microglial cell mediated cytotoxicity + 3
          natural killer cell mediated cytotoxicity + 75
          negative regulation of leukocyte mediated cytotoxicity + 26
          neutrophil mediated cytotoxicity + 16
          positive regulation of leukocyte mediated cytotoxicity + 64
          regulation of leukocyte mediated cytotoxicity + 89
Path 2
Term Annotations click to browse term
  biological_process 20078
    immune system process 2843
      immune effector process 902
        leukocyte mediated immunity 513
          leukocyte mediated cytotoxicity 127
            T cell mediated cytotoxicity + 50
            antibody-dependent cellular cytotoxicity + 4
            microglial cell mediated cytotoxicity + 3
            natural killer cell mediated cytotoxicity + 75
            negative regulation of leukocyte mediated cytotoxicity + 26
            neutrophil mediated cytotoxicity + 16
            positive regulation of leukocyte mediated cytotoxicity + 64
            regulation of leukocyte mediated cytotoxicity + 89
paths to the root