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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-azacytidine
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Accession:CHEBI:2038 term browser browse the term
Definition:An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia.
Synonyms:exact_synonym: 4-amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
 related_synonym: 4-Amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one;   Azacitidine;   Formula=C8H12N4O5;   InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1;   InChIKey=NMUSYJAQQFHJEW-KVTDHHQDSA-N;   SMILES=Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1;   azacitidina;   azacitidinum
 xref: CAS:320-67-2;   DrugBank:DB00928;   Drug_Central:25;   HMDB:HMDB0015063;   KEGG:C11262;   KEGG:D03021;   LINCS:LSM-5218
 xref_mesh: MESH:D001374
 xref: PMID:11841042;   PMID:15962522;   PMID:17611569;   PMID:28131982;   PMID:28415666;   PMID:28486212;   PMID:29438107;   Patent:KR20140069225;   Patent:US2015038444;   Reaxys:620461;   Wikipedia:Azacitidine


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5-azacytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle multiple interactions EXP Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:22841775 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 decreases expression EXP Azacitidine results in decreased expression of ADAMTS1 mRNA CTD PMID:20823114 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADRB1 adrenoceptor beta 1 affects expression ISO Azacitidine affects the expression of ADRB1 mRNA CTD PMID:19002953 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ADRB2 adrenoceptor beta 2 affects expression
multiple interactions		 ISO
EXP		 Azacitidine affects the expression of ADRB2 mRNA
Azacitidine inhibits the reaction [Particulate Matter results in decreased expression of ADRB2 mRNA]		 CTD PMID:19002953 PMID:30986742 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G AFP alpha fetoprotein increases expression EXP Azacitidine results in increased expression of AFP mRNA CTD PMID:27590069 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174 		JBrowse link
G AGGF1 angiogenic factor with G-patch and FHA domains 1 increases expression EXP Azacitidine results in increased expression of AGGF1 mRNA CTD PMID:19194470 NCBI chr 5:77,030,404...77,065,234
Ensembl chr 5:77,029,251...77,065,234 		JBrowse link
G AHR aryl hydrocarbon receptor increases expression
multiple interactions		 EXP
ISO		 Azacitidine results in increased expression of AHR mRNA
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]		 CTD PMID:12927368 PMID:17682057 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AK5 adenylate kinase 5 increases expression EXP Azacitidine results in increased expression of AK5 mRNA CTD PMID:20823114 NCBI chr 1:77,282,019...77,559,966
Ensembl chr 1:77,282,019...77,559,966 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:22841775 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALAD aminolevulinate dehydratase decreases expression EXP Azacitidine results in decreased expression of ALAD mRNA CTD PMID:19194470 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G ALB albumin decreases expression
increases expression		 EXP Azacitidine results in decreased expression of ALB protein
Azacitidine results in increased expression of ALB mRNA		 CTD PMID:27590069 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]] CTD PMID:17682057 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G ANXA1 annexin A1 decreases expression ISO Azacitidine results in decreased expression of ANXA1 protein CTD PMID:17105402 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F increases expression EXP Azacitidine results in increased expression of APOBEC3F mRNA CTD PMID:19194470 NCBI chr22:39,040,864...39,055,972
Ensembl chr22:39,040,604...39,055,972 		JBrowse link
G APOBEC3G apolipoprotein B mRNA editing enzyme catalytic subunit 3G increases expression EXP Azacitidine results in increased expression of APOBEC3G mRNA CTD PMID:19194470 NCBI chr22:39,077,005...39,087,743
Ensembl chr22:39,077,067...39,087,743 		JBrowse link
G APP amyloid beta precursor protein decreases methylation
multiple interactions		 ISO Azacitidine results in decreased methylation of APP promoter
Azacitidine results in increased expression of and results in increased cleavage of APP protein; Betaine inhibits the reaction [Azacitidine results in decreased methylation of APP promoter]; Betaine inhibits the reaction [Azacitidine results in increased expression of and results in increased cleavage of APP protein]		 CTD PMID:19635394 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G AQP5 aquaporin 5 decreases methylation
increases expression
multiple interactions		 ISO Azacitidine results in decreased methylation of AQP5 promoter
Azacitidine results in increased expression of AQP5 protein
[Azacitidine results in decreased methylation of AQP5 promoter] which results in increased expression of AQP5 mRNA; Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]		 CTD PMID:17198683 NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682 		JBrowse link
G AQP9 aquaporin 9 multiple interactions
increases expression		 EXP [Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide; HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA] CTD PMID:25953102 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911 		JBrowse link
G AR androgen receptor multiple interactions
increases expression		 EXP [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to bicalutamide; [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to Dihydrotestosterone CTD PMID:18324645 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 increases expression EXP Azacitidine results in increased expression of ARHGAP35 mRNA CTD PMID:20823114 NCBI chr19:46,860,997...47,005,077
Ensembl chr19:46,860,997...47,005,077 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression EXP Azacitidine results in decreased expression of ARHGEF2 mRNA CTD PMID:20823114 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G ART1 ADP-ribosyltransferase 1 increases expression EXP Azacitidine results in increased expression of ART1 mRNA CTD PMID:20823114 NCBI chr11:3,645,128...3,664,416
Ensembl chr11:3,645,128...3,664,416 		JBrowse link
G ASB2 ankyrin repeat and SOCS box containing 2 increases expression EXP Azacitidine results in increased expression of ASB2 mRNA CTD PMID:20823114 NCBI chr14:93,934,166...93,976,570
Ensembl chr14:93,934,166...93,976,739 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 decreases expression EXP Azacitidine results in decreased expression of ATP2B1 mRNA CTD PMID:20823114 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366 		JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c increases expression EXP Azacitidine results in increased expression of ATP6V0C mRNA CTD PMID:20823114 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218 		JBrowse link
G AURKA aurora kinase A multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337 		JBrowse link
G BAD BCL2 associated agonist of cell death increases expression
multiple interactions		 ISO Azacitidine results in increased expression of BAD mRNA
[Azacitidine co-treated with entinostat] results in increased expression of BAD mRNA		 CTD PMID:21224363 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 multiple interactions
increases expression		 ISO [Azacitidine co-treated with entinostat] results in increased expression of BAK1 mRNA
Azacitidine results in increased expression of BAK1 mRNA		 CTD PMID:21224363 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO Azacitidine results in increased expression of BAX mRNA
Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]		 CTD PMID:32278510 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 decreases expression EXP Azacitidine results in decreased expression of BCAT1 mRNA CTD PMID:20823114 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 ISO Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
Azacitidine results in decreased expression of BCL2 mRNA; Azacitidine results in decreased expression of BCL2 protein		 CTD PMID:32278510 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions
affects expression		 EXP [metacept-1 co-treated with Azacitidine] results in decreased expression of BCL2L1
[Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein		 CTD PMID:18443271 PMID:19148494 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCL2L13 BCL2 like 13 increases expression EXP Azacitidine results in increased expression of BCL2L13 mRNA CTD PMID:20823114 NCBI chr22:17,628,877...17,730,855
Ensembl chr22:17,628,855...17,730,855 		JBrowse link
G BDNF brain derived neurotrophic factor increases expression
decreases methylation
multiple interactions		 ISO Azacitidine results in increased expression of BDNF mRNA
Azacitidine results in decreased methylation of BDNF promoter
Tetrodotoxin inhibits the reaction [Azacitidine results in decreased methylation of BDNF promoter]; Tetrodotoxin inhibits the reaction [Azacitidine results in increased expression of BDNF mRNA]		 CTD PMID:18184782 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein decreases expression ISO Azacitidine results in decreased expression of BGLAP protein CTD PMID:18037191 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BICD1 BICD cargo adaptor 1 decreases expression EXP Azacitidine results in decreased expression of BICD1 mRNA CTD PMID:20823114 NCBI chr12:32,106,847...32,383,633
Ensembl chr12:32,106,835...32,383,633 		JBrowse link
G BIK BCL2 interacting killer multiple interactions
increases expression		 ISO [Azacitidine co-treated with entinostat] results in increased expression of BIK mRNA
Azacitidine results in increased expression of BIK mRNA		 CTD PMID:21224363 NCBI chr22:43,110,750...43,129,712
Ensembl chr22:43,110,750...43,129,712 		JBrowse link
G BMP15 bone morphogenetic protein 15 increases expression ISO Azacitidine results in increased expression of BMP15 mRNA CTD PMID:23395740 NCBI chr  X:50,910,735...50,916,641
Ensembl chr  X:50,910,735...50,916,641 		JBrowse link
G BNIP3 BCL2 interacting protein 3 increases expression EXP Azacitidine results in increased expression of BNIP3 mRNA CTD PMID:25446377 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK multiple interactions
increases expression		 ISO [Azacitidine co-treated with entinostat] results in increased expression of BOK mRNA
Azacitidine results in increased expression of BOK mRNA		 CTD PMID:21224363 NCBI chr 2:241,551,393...241,574,131
Ensembl chr 2:241,551,424...241,574,131 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of BUB1B mRNA CTD PMID:18720364 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123 		JBrowse link
G C3AR1 complement C3a receptor 1 increases expression EXP Azacitidine results in increased expression of C3AR1 mRNA CTD PMID:19194470 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C6orf62 chromosome 6 open reading frame 62 increases expression EXP Azacitidine results in increased expression of C6ORF62 mRNA CTD PMID:19194470 NCBI chr 6:24,704,861...24,720,836
Ensembl chr 6:24,704,861...24,720,825 		JBrowse link
G CALCA calcitonin related polypeptide alpha decreases methylation EXP Azacitidine results in decreased methylation of CALCA promoter CTD PMID:19299654 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CALD1 caldesmon 1 increases expression EXP Azacitidine results in increased expression of CALD1 mRNA CTD PMID:20823114 NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729 		JBrowse link
G CALHM2 calcium homeostasis modulator family member 2 multiple interactions
increases expression		 EXP Cisplatin affects the reaction [Azacitidine results in increased expression of CALHM2 mRNA] CTD PMID:36336710 NCBI chr10:103,446,786...103,452,370
Ensembl chr10:103,446,786...103,452,402 		JBrowse link
G CASP10 caspase 10 increases expression EXP Azacitidine results in increased expression of CASP10 mRNA CTD PMID:19194470 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,872...201,229,428 		JBrowse link
G CASP3 caspase 3 affects expression
increases activity
increases expression
multiple interactions		 EXP
ISO		 Azacitidine affects the expression of CASP3 protein
5-azacytidine co-treated with doxorubicin increases activity of CASP3 protein in lung cancer cells
Azacitidine results in increased expression of CASP3 mRNA
[metacept-1 co-treated with Azacitidine] results in increased expression of CASP3		 CTD
RGD		 PMID:18443271 PMID:19148494 PMID:23395740 PMID:24356455 RGD:153344603 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 increases expression EXP
ISO		 Azacitidine results in increased expression of CASP8 mRNA CTD PMID:18082045 PMID:23395740 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases expression ISO Azacitidine results in increased expression of CASP9 mRNA CTD PMID:23395740 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCNA1 cyclin A1 multiple interactions
decreases expression		 EXP Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter]; Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter]; Azacitidine promotes the reaction [H4C16 protein modified form binds to CCNA1 promoter]
Azacitidine results in decreased expression of CCNA1 mRNA		 CTD PMID:17698632 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCNA2 cyclin A2 multiple interactions
decreases expression		 EXP [Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA
Azacitidine results in decreased expression of CCNA2 mRNA		 CTD PMID:18720364 PMID:20823114 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 multiple interactions
increases expression		 EXP [Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA
Azacitidine results in increased expression of CCNB1 protein		 CTD PMID:18720364 PMID:20607034 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 increases expression EXP Azacitidine results in increased expression of CCND1 mRNA CTD PMID:20823114 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND2 cyclin D2 affects methylation
multiple interactions		 EXP Azacitidine affects the methylation of CCND2 promoter
[Azacitidine affects the methylation of CCND2 promoter] which affects the expression of CCND2 mRNA		 CTD PMID:17016690 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CCNG2 cyclin G2 decreases expression EXP Azacitidine results in decreased expression of CCNG2 mRNA CTD PMID:21245298 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CD274 CD274 molecule multiple interactions EXP Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]] CTD PMID:32894642 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CDC20 cell division cycle 20 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of CDC20 mRNA CTD PMID:18720364 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203 		JBrowse link
G CDC42BPA CDC42 binding protein kinase alpha decreases expression EXP Azacitidine results in decreased expression of CDC42BPA mRNA CTD PMID:20823114 NCBI chr 1:226,989,858...227,318,492
Ensembl chr 1:226,989,865...227,318,492 		JBrowse link
G CDH1 cadherin 1 decreases methylation
increases expression		 EXP Azacitidine results in decreased methylation of CDH1 promoter
Azacitidine results in increased expression of CDH1 mRNA		 CTD PMID:17520682 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH2 cadherin 2 increases expression ISO Azacitidine results in increased expression of CDH2 mRNA CTD PMID:18037191 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CDK1 cyclin dependent kinase 1 multiple interactions
increases expression		 EXP [Azacitidine co-treated with Thalidomide] affects the expression of CDK1 mRNA
Azacitidine analog results in increased expression of CDK1 protein		 CTD PMID:18324645 PMID:18720364 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP Azacitidine analog results in decreased expression of CDK2 protein CTD PMID:18324645 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression EXP Azacitidine analog results in decreased expression of CDK4 protein CTD PMID:18324645 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 EXP
ISO		 Azacitidine analog results in increased expression of CDKN1A protein; Azacitidine results in increased expression of CDKN1A mRNA
[Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN1A		 CTD PMID:18324645 PMID:19148494 PMID:20823114 PMID:21224363 PMID:25015661 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C increases expression EXP Azacitidine results in increased expression of CDKN1C mRNA CTD PMID:19194470 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A affects methylation
multiple interactions
increases expression
decreases methylation		 EXP
ISO		 Azacitidine affects the methylation of CDKN2A gene
Azacitidine inhibits the reaction [Particulate Matter results in increased methylation of CDKN2A promoter]
Azacitidine results in increased expression of CDKN2A mRNA
Azacitidine results in decreased methylation of CDKN2A gene
[Azacitidine co-treated with entinostat] results in decreased methylation of CDKN2A gene; [Azacitidine co-treated with entinostat] results in increased expression of CDKN2A mRNA
Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of CDKN2A gene]		 CTD PMID:17686055 PMID:18443271 PMID:21224363 PMID:22355787 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B decreases methylation
multiple interactions
affects response to substance		 EXP Azacitidine results in decreased methylation of CDKN2B promoter
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN2B
CDKN2B promoter modified form affects the susceptibility to Azacitidine		 CTD PMID:17611569 PMID:19148494 PMID:19194470 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha decreases methylation
increases expression		 EXP Azacitidine results in decreased methylation of CEBPA promoter
Azacitidine results in increased expression of CEBPA mRNA		 CTD PMID:19194470 PMID:27590069 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CENPA centromere protein A multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of CENPA mRNA CTD PMID:18720364 NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067 		JBrowse link
G CENPF centromere protein F multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of CENPF mRNA CTD PMID:18720364 NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574 		JBrowse link
G CENPO centromere protein O increases expression EXP Azacitidine results in increased expression of CENPO mRNA CTD PMID:19194470 NCBI chr 2:24,793,425...24,822,376
Ensembl chr 2:24,793,136...24,822,376 		JBrowse link
G CHAT choline O-acetyltransferase increases expression ISO Azacitidine results in increased expression of CHAT mRNA; Azacitidine results in increased expression of CHAT protein CTD PMID:19151599 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CHGA chromogranin A decreases expression EXP Azacitidine results in decreased expression of CHGA protein CTD PMID:20607034 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285 		JBrowse link
G CHIT1 chitinase 1 increases expression EXP Azacitidine results in increased expression of CHIT1 mRNA CTD PMID:20823114 NCBI chr 1:203,216,079...203,230,099
Ensembl chr 1:203,212,827...203,273,641 		JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 affects expression ISO Azacitidine affects the expression of CHRM1 mRNA CTD PMID:19002953 NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 affects expression ISO Azacitidine affects the expression of CHRM2 mRNA CTD PMID:19002953 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255 		JBrowse link
G CHST14 carbohydrate sulfotransferase 14 increases expression ISO Azacitidine results in increased expression of CHST14 mRNA CTD PMID:27415467 NCBI chr15:40,470,984...40,473,158
Ensembl chr15:40,470,984...40,473,158 		JBrowse link
G CIITA class II major histocompatibility complex transactivator multiple interactions
increases expression		 EXP [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]
Azacitidine results in increased expression of CIITA mRNA		 CTD PMID:18829986 PMID:20823114 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021 		JBrowse link
G CLDN10 claudin 10 decreases expression EXP Azacitidine results in decreased expression of CLDN10 mRNA CTD PMID:19194470 NCBI chr13:95,433,755...95,579,759
Ensembl chr13:95,433,604...95,579,759 		JBrowse link
G CLDN6 claudin 6 increases expression
decreases methylation
multiple interactions		 EXP Azacitidine results in increased expression of CLDN6 mRNA
Azacitidine results in decreased methylation of CLDN6 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN6 promoter		 CTD PMID:18661270 NCBI chr16:3,014,712...3,018,183
Ensembl chr16:3,014,712...3,020,071 		JBrowse link
G CLDN7 claudin 7 decreases expression
multiple interactions		 EXP Azacitidine results in decreased expression of CLDN7 mRNA
Cisplatin affects the reaction [Azacitidine results in decreased expression of CLDN7 mRNA]		 CTD PMID:36336710 NCBI chr17:7,259,903...7,263,213
Ensembl chr17:7,259,903...7,263,983 		JBrowse link
G CLDN8 claudin 8 increases expression EXP Azacitidine results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr21:30,214,006...30,216,097
Ensembl chr21:30,214,006...30,216,097 		JBrowse link
G CLDN9 claudin 9 decreases methylation
multiple interactions
increases expression		 EXP Azacitidine results in decreased methylation of CLDN9 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN9 promoter
Azacitidine results in increased expression of CLDN9 mRNA		 CTD PMID:18661270 NCBI chr16:3,012,923...3,014,505
Ensembl chr16:3,012,923...3,014,505 		JBrowse link
G CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 decreases expression EXP Azacitidine results in decreased expression of CNNM2 mRNA CTD PMID:19194470 NCBI chr10:102,918,294...103,090,222
Ensembl chr10:102,918,294...103,090,222 		JBrowse link
G COL14A1 collagen type XIV alpha 1 chain increases expression EXP Azacitidine results in increased expression of COL14A1 mRNA CTD PMID:19194470 NCBI chr 8:120,124,454...120,373,573
Ensembl chr 8:120,059,780...120,373,573 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] CTD PMID:22841775 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain decreases expression EXP Azacitidine results in decreased expression of COL6A3 mRNA CTD PMID:20823114 NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328 		JBrowse link
G COL9A3 collagen type IX alpha 3 chain decreases expression ISO Azacitidine results in decreased expression of COL9A3 mRNA CTD PMID:18033690 NCBI chr20:62,816,213...62,841,159
Ensembl chr20:62,816,244...62,841,159 		JBrowse link
G COX6A2 cytochrome c oxidase subunit 6A2 increases expression EXP Azacitidine results in increased expression of COX6A2 mRNA CTD PMID:20823114 NCBI chr16:31,427,731...31,428,360
Ensembl chr16:31,427,731...31,428,360 		JBrowse link
G CPE carboxypeptidase E increases expression EXP Azacitidine results in increased expression of CPE mRNA CTD PMID:20823114 NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547 		JBrowse link
G CPLX1 complexin 1 increases expression EXP Azacitidine results in increased expression of CPLX1 mRNA CTD PMID:20823114 NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions EXP Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter] CTD PMID:19155497 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CREB3L4 cAMP responsive element binding protein 3 like 4 increases expression ISO Azacitidine results in increased expression of CREB3L4 mRNA CTD PMID:27415467 NCBI chr 1:153,967,487...153,974,359
Ensembl chr 1:153,967,534...153,974,361 		JBrowse link
G CREM cAMP responsive element modulator decreases expression EXP Azacitidine results in decreased expression of CREM mRNA CTD PMID:20823114 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CRYAA crystallin alpha A increases expression ISO Azacitidine results in increased expression of CRYAA protein CTD PMID:17105402 NCBI chr21:43,169,008...43,172,810
Ensembl chr21:43,169,008...43,172,805 		JBrowse link
G CRYAB crystallin alpha B increases expression ISO Azacitidine results in increased expression of CRYAB protein CTD PMID:17105402 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CSF1 colony stimulating factor 1 increases expression ISO Azacitidine results in increased expression of CSF1 mRNA CTD PMID:17156202 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CSN1S1 casein alpha s1 increases expression EXP Azacitidine results in increased expression of CSN1S1 mRNA CTD PMID:20823114 NCBI chr 4:69,931,068...69,946,574
Ensembl chr 4:69,931,068...69,946,574 		JBrowse link
G CST3 cystatin C increases expression EXP Azacitidine results in increased expression of CST3 mRNA CTD PMID:20823114 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473 		JBrowse link
G CST4 cystatin S increases expression EXP Azacitidine results in increased expression of CST4 mRNA CTD PMID:20823114 NCBI chr20:23,685,640...23,689,038
Ensembl chr20:23,685,640...23,689,038 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases methylation
increases expression		 EXP Azacitidine results in decreased methylation of CXCL12 promoter
Azacitidine results in increased expression of CXCL12 mRNA; Azacitidine results in increased expression of CXCL12 protein		 CTD PMID:19748759 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression		 EXP
ISO		 Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]
Azacitidine results in increased expression of CYP1A1 mRNA		 CTD PMID:11281733 PMID:12927368 PMID:17682057 PMID:27590069 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions
increases expression		 EXP Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
Azacitidine results in increased expression of CYP1A2 mRNA		 CTD PMID:12927368 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 multiple interactions
increases expression		 EXP Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Azacitidine results in increased expression of CYP1B1 mRNA		 CTD PMID:12927368 PMID:27590069 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression EXP Azacitidine results in increased expression of CYP3A4 mRNA CTD PMID:27590069 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYTH1 cytohesin 1 increases expression EXP Azacitidine results in increased expression of CYTH1 mRNA CTD PMID:19194470 NCBI chr17:78,674,048...78,782,273
Ensembl chr17:78,674,048...78,782,297 		JBrowse link
G DAPK1 death associated protein kinase 1 affects methylation EXP Azacitidine affects the methylation of DAPK1 promoter CTD PMID:17557868 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634 		JBrowse link
G DCN decorin multiple interactions
decreases expression		 EXP Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein]
Azacitidine results in decreased expression of DCN mRNA		 CTD PMID:20823114 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217 		JBrowse link
G DES desmin increases expression
multiple interactions		 ISO
EXP		 Azacitidine results in increased expression of DES mRNA; Azacitidine results in increased expression of DES protein
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA		 CTD PMID:18037191 PMID:20823114 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DHX9 DExH-box helicase 9 decreases expression EXP Azacitidine results in decreased expression of DHX9 mRNA CTD PMID:20823114 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982 		JBrowse link
G DIO2 iodothyronine deiodinase 2 decreases expression EXP Azacitidine results in decreased expression of DIO2 mRNA CTD PMID:20823114 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 decreases methylation EXP Azacitidine results in decreased methylation of DLK1 promoter CTD PMID:19194470 NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224 		JBrowse link
G DLX5 distal-less homeobox 5 increases expression ISO Azacitidine results in increased expression of DLX5 mRNA CTD PMID:17085970 NCBI chr 7:97,020,396...97,024,831
Ensembl chr 7:97,020,396...97,024,950 		JBrowse link
G DLX6 distal-less homeobox 6 increases expression EXP Azacitidine results in increased expression of DLX6 mRNA CTD PMID:20823114 NCBI chr 7:97,005,553...97,011,040
Ensembl chr 7:97,005,553...97,011,040 		JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions
decreases expression		 EXP
ISO		 [SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Arsenic Trioxide promotes the reaction [Azacitidine results in decreased expression of DNMT1 protein]; Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter]
[Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein; [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein		 CTD PMID:19139132 PMID:19723570 PMID:21224363 PMID:28901456 PMID:35066776 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter] CTD PMID:35066776 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta multiple interactions EXP Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter] CTD PMID:35066776 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase decreases methylation
multiple interactions
decreases response to substance		 EXP Azacitidine results in decreased methylation of DPYD promoter
[Azacitidine results in decreased methylation of DPYD promoter] which results in increased expression of DPYD mRNA
DPYD protein results in decreased susceptibility to Azacitidine		 CTD PMID:15501990 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000 		JBrowse link
G DUSP1 dual specificity phosphatase 1 increases expression EXP Azacitidine results in increased expression of DUSP1 mRNA CTD PMID:20823114 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP6 dual specificity phosphatase 6 increases expression EXP Azacitidine results in increased expression of DUSP6 mRNA CTD PMID:21245298 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G E2F1 E2F transcription factor 1 multiple interactions EXP E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA] CTD PMID:19451745 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 decreases expression EXP Azacitidine results in decreased expression of EEF1A1 mRNA CTD PMID:20823114 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587 		JBrowse link
G EFNA3 ephrin A3 increases expression EXP Azacitidine results in increased expression of EFNA3 mRNA CTD PMID:20823114 NCBI chr 1:155,078,837...155,087,538
Ensembl chr 1:155,078,837...155,087,538 		JBrowse link
G EGR2 early growth response 2 increases expression EXP Azacitidine results in increased expression of EGR2 mRNA CTD PMID:20823114 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167 		JBrowse link
G EIF3LP3 eukaryotic translation initiation factor 3 subunit L pseudogene 3 decreases expression EXP Azacitidine results in decreased expression of EIF3LP3 mRNA CTD PMID:20823114 NCBI chr10:38,079,901...38,080,863
Ensembl chr10:38,080,056...38,080,877 		JBrowse link
G ENO2 enolase 2 decreases expression EXP Azacitidine results in decreased expression of ENO2 protein CTD PMID:20607034 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression EXP Azacitidine results in increased expression of ENTPD1 mRNA CTD PMID:20823114 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ESR1 estrogen receptor 1 increases expression EXP Azacitidine results in increased expression of ESR1 protein CTD PMID:22558281 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor multiple interactions EXP Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558 		JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 decreases expression EXP Azacitidine results in decreased expression of EYA1 mRNA CTD PMID:20823114 NCBI chr 8:71,197,433...71,548,094
Ensembl chr 8:71,197,433...71,592,025 		JBrowse link
G FADS2 fatty acid desaturase 2 decreases expression EXP Azacitidine results in decreased expression of FADS2 mRNA CTD PMID:20823114 NCBI chr11:61,816,203...61,867,354
Ensembl chr11:61,792,980...61,867,354 		JBrowse link
G FAM8A1 family with sequence similarity 8 member A1 increases expression EXP Azacitidine results in increased expression of FAM8A1 mRNA CTD PMID:19194470 NCBI chr 6:17,600,302...17,611,715
Ensembl chr 6:17,600,302...17,611,719 		JBrowse link
G FASLG Fas ligand increases response to substance ISO
EXP		 Azacitidine results in increased susceptibility to FASLG protein CTD PMID:18829727 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FBLN1 fibulin 1 increases expression EXP Azacitidine results in increased expression of FBLN1 mRNA CTD PMID:21245298 NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNA CTD PMID:18720364 NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238 		JBrowse link
G FGF7 fibroblast growth factor 7 decreases expression EXP Azacitidine results in decreased expression of FGF7 mRNA CTD PMID:20823114 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FILIP1L filamin A interacting protein 1 like decreases expression EXP Azacitidine results in decreased expression of FILIP1L mRNA CTD PMID:20823114 NCBI chr 3:99,828,811...100,114,501
Ensembl chr 3:99,828,811...100,114,513 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA CTD PMID:20823114 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FOXP3 forkhead box P3 multiple interactions ISO [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein; [Azacitidine results in decreased methylation of FOXP3 gene] which results in increased expression of FOXP3 protein CTD PMID:18493985 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FTL ferritin light chain decreases expression ISO Azacitidine results in decreased expression of FTL1 protein CTD PMID:17105402 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase increases expression EXP Azacitidine results in increased expression of FYN mRNA CTD PMID:21245298 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G GABARAPL3 GABA type A receptor associated protein like 3 (pseudogene) increases expression EXP Azacitidine results in increased expression of GABARAPL3 mRNA CTD PMID:19194470 NCBI chr15:90,346,527...90,349,447
Ensembl chr15:90,348,844...90,349,197 		JBrowse link
G GABRB1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression EXP Azacitidine results in increased expression of GABRB1 mRNA CTD PMID:19194470 NCBI chr 4:46,993,647...47,426,447
Ensembl chr 4:46,993,723...47,426,447 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha decreases methylation
multiple interactions
increases expression		 EXP Azacitidine results in decreased methylation of GADD45A promoter
[Azacitidine results in increased expression of GADD45A protein] which results in increased susceptibility to docetaxel
Azacitidine results in increased expression of GADD45A mRNA; Azacitidine results in increased expression of GADD45A protein		 CTD PMID:19190346 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta multiple interactions EXP Azacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B] CTD PMID:18225533 NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,259 		JBrowse link
G GATA4 GATA binding protein 4 increases expression ISO Azacitidine results in increased expression of GATA4 mRNA; Azacitidine results in increased expression of GATA4 protein CTD PMID:18037191 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002 		JBrowse link
G GBP2 guanylate binding protein 2 decreases expression EXP Azacitidine results in decreased expression of GBP2 mRNA CTD PMID:20823114 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) decreases expression EXP Azacitidine results in decreased expression of GCNT2 mRNA CTD PMID:20823114 NCBI chr 6:10,521,351...10,629,368
Ensembl chr 6:10,492,223...10,629,368 		JBrowse link
G GDF9 growth differentiation factor 9 increases expression ISO Azacitidine results in increased expression of GDF9 mRNA CTD PMID:23395740 NCBI chr 5:132,861,185...132,866,651
Ensembl chr 5:132,861,181...132,866,884 		JBrowse link
G GJA1 gap junction protein alpha 1 increases expression
decreases expression		 ISO
EXP		 Azacitidine results in increased expression of GJA1 protein
Azacitidine results in decreased expression of GJA1 mRNA		 CTD PMID:18037191 PMID:20823114 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GNG7 G protein subunit gamma 7 affects methylation EXP Azacitidine affects the methylation of GNG7 promoter CTD PMID:18219292 NCBI chr19:2,511,219...2,702,694
Ensembl chr19:2,511,219...2,702,694 		JBrowse link
G GPKOW G-patch domain and KOW motifs increases expression EXP Azacitidine results in increased expression of GPKOW mRNA CTD PMID:20823114 NCBI chr  X:49,113,407...49,123,735
Ensembl chr  X:49,113,407...49,123,735 		JBrowse link
G GPNMB glycoprotein nmb decreases expression EXP Azacitidine results in decreased expression of GPNMB mRNA CTD PMID:20823114 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108 		JBrowse link
G GPX3 glutathione peroxidase 3 increases expression EXP 5-azacytidine increases expression of GPX3 mRNA in epithelial cells of stomach RGD PMID:16229808 RGD:151665354 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B decreases methylation ISO Azacitidine results in decreased methylation of GRIN2B gene CTD PMID:18618247 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002 		JBrowse link
G GUK1 guanylate kinase 1 increases expression EXP Azacitidine results in increased expression of GUK1 mRNA CTD PMID:20823114 NCBI chr 1:228,140,084...228,148,955
Ensembl chr 1:228,139,962...228,148,984 		JBrowse link
G GZMB granzyme B multiple interactions EXP Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein] CTD PMID:19394699 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267 		JBrowse link
G H1-0 H1.0 linker histone increases expression EXP Azacitidine results in increased expression of H1-0 protein CTD PMID:16006241 NCBI chr22:37,805,229...37,807,432
Ensembl chr22:37,805,229...37,807,432 		JBrowse link
G H2AX H2A.X variant histone increases expression
multiple interactions		 EXP
ISO		 Azacitidine results in increased expression of H2AX protein
Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]		 CTD PMID:17991895 PMID:25015661 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G H3-4 H3.4 histone, cluster member multiple interactions EXP Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr 1:228,424,845...228,425,360
Ensembl chr 1:228,424,845...228,425,360 		JBrowse link
G H4C16 H4 histone 16 multiple interactions EXP Azacitidine promotes the reaction [H4C16 protein modified form binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr12:14,770,720...14,771,131
Ensembl chr12:14,767,999...14,771,131 		JBrowse link
G HGD homogentisate 1,2-dioxygenase increases expression EXP Azacitidine results in increased expression of HGD mRNA CTD PMID:20823114 NCBI chr 3:120,628,172...120,682,239
Ensembl chr 3:120,628,172...120,682,269 		JBrowse link
G HGF hepatocyte growth factor increases expression EXP Azacitidine results in increased expression of HGF mRNA CTD PMID:19194470 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HHEX hematopoietically expressed homeobox increases expression EXP Azacitidine results in increased expression of HHEX mRNA CTD PMID:27590069 NCBI chr10:92,689,955...92,695,647
Ensembl chr10:92,689,955...92,695,647 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha multiple interactions EXP [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein CTD PMID:18829986 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HMGA1 high mobility group AT-hook 1 increases expression EXP Azacitidine results in increased expression of HMGA1 mRNA CTD PMID:20823114 NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231 		JBrowse link
G HMGA2 high mobility group AT-hook 2 increases expression
multiple interactions		 EXP Azacitidine results in increased expression of HMGA2 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]		 CTD PMID:21245298 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G HMGB1 high mobility group box 1 multiple interactions
decreases expression		 ISO Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA] CTD PMID:32278510 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HNF1A HNF1 homeobox A decreases methylation
multiple interactions
increases expression		 EXP Azacitidine results in decreased methylation of HNF1A promoter
HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]
Azacitidine results in increased expression of HNF1A mRNA; Azacitidine results in increased expression of HNF1A protein		 CTD PMID:25953102 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha increases expression EXP Azacitidine results in increased expression of HNF4A mRNA CTD PMID:27590069 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HOXA1 homeobox A1 multiple interactions
increases expression		 EXP Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA]
Azacitidine results in increased expression of HOXA1 mRNA		 CTD PMID:20823114 NCBI chr 7:27,092,993...27,096,000
Ensembl chr 7:27,092,993...27,096,000 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase decreases methylation
multiple interactions
increases expression		 EXP Azacitidine results in decreased methylation of HPGD gene
trichostatin A promotes the reaction [Azacitidine results in increased expression of HPGD mRNA]		 CTD PMID:19584167 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects expression ISO Azacitidine affects the expression of HSD3B1 mRNA CTD PMID:18033690 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSF1 heat shock transcription factor 1 decreases activity EXP Azacitidine results in decreased activity of HSF1 protein CTD PMID:34170685 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP Azacitidine results in increased expression of HSPA6 mRNA CTD PMID:19194470 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894 		JBrowse link
G ID1 inhibitor of DNA binding 1 increases expression EXP Azacitidine results in increased expression of ID1 mRNA CTD PMID:19194470 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G ID3 inhibitor of DNA binding 3 increases expression EXP Azacitidine results in increased expression of ID3 mRNA CTD PMID:19194470 NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501 		JBrowse link
G IFNG interferon gamma multiple interactions EXP [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]; [Azacitidine results in increased expression of KIR2DL4 protein] which results in increased secretion of IFNG protein CTD PMID:18829986 PMID:18945643 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 multiple interactions
increases expression		 EXP Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein]
Azacitidine results in increased expression of IGFBP1 mRNA		 CTD PMID:20823114 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 increases expression EXP Azacitidine results in increased expression of IGFBP4 mRNA CTD PMID:20823114 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IL12B interleukin 12B increases expression EXP Azacitidine results in increased expression of IL12B mRNA CTD PMID:20823114 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions		 ISO
EXP		 Azacitidine results in increased expression of IL1B mRNA
Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]]		 CTD PMID:17156202 PMID:32894642 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 multiple interactions EXP Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein]; Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL4 interleukin 4 affects methylation EXP Azacitidine affects the methylation of IL4 promoter CTD PMID:18158872 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 affects secretion
affects methylation		 EXP Azacitidine affects the secretion of IL6 protein
Azacitidine affects the methylation of IL6 promoter		 CTD PMID:18158872 PMID:18443271 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor affects expression
multiple interactions		 EXP [Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein; Azacitidine affects the expression of IL6R mRNA
[Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein		 CTD PMID:18443271 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G ISCA1 iron-sulfur cluster assembly 1 increases expression EXP Azacitidine results in increased expression of ISCA1 mRNA CTD PMID:19194470 NCBI chr 9:86,264,546...86,282,538
Ensembl chr 9:86,264,546...86,283,102 		JBrowse link
G ITGB1 integrin subunit beta 1 decreases expression EXP Azacitidine results in decreased expression of ITGB1 mRNA CTD PMID:20823114 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITGB2 integrin subunit beta 2 decreases expression EXP Azacitidine results in decreased expression of ITGB2 mRNA CTD PMID:19194470 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G ITPRID2 ITPR interacting domain containing 2 increases expression EXP Azacitidine results in increased expression of ITPRID2 mRNA CTD PMID:20823114 NCBI chr 2:181,891,730...181,930,738
Ensembl chr 2:181,891,730...181,930,738 		JBrowse link
G KDR kinase insert domain receptor increases expression ISO Azacitidine results in increased expression of KDR mRNA CTD PMID:18037191 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KIF2C kinesin family member 2C multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of KIF2C mRNA CTD PMID:18720364 NCBI chr 1:44,739,837...44,767,767
Ensembl chr 1:44,739,818...44,767,767 		JBrowse link
G KIR2DL1 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 increases expression
decreases methylation		 EXP Azacitidine results in increased expression of KIR2DL1 mRNA; Azacitidine results in increased expression of KIR2DL1 protein
Azacitidine results in decreased methylation of KIR2DL1 promoter		 CTD PMID:18945643 PMID:19394699 NCBI chr19:54,769,793...54,784,322
Ensembl chr19:54,769,793...54,784,322 		JBrowse link
G KIR2DL2 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 multiple interactions
decreases methylation
increases expression		 EXP Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [SP1 protein binds to KIR2DL2 promoter]
Azacitidine results in decreased methylation of KIR2DL2 promoter
Azacitidine results in increased expression of KIR2DL2 mRNA; Azacitidine results in increased expression of KIR2DL2 protein		 CTD PMID:18945643 PMID:19394699
G KIR2DL3 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 decreases methylation
increases expression		 EXP Azacitidine results in decreased methylation of KIR2DL3 promoter
Azacitidine results in increased expression of KIR2DL3 mRNA; Azacitidine results in increased expression of KIR2DL3 protein		 CTD PMID:18945643 PMID:19394699 NCBI chr19:54,738,513...54,753,052
Ensembl chr19:54,738,513...54,753,052 		JBrowse link
G KIR2DL4 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 multiple interactions
increases expression
decreases methylation		 EXP [Azacitidine results in increased expression of KIR2DL4 protein] which results in increased secretion of IFNG protein; Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL4 promoter]; Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL4 promoter]; Azacitidine promotes the reaction [SP1 protein binds to KIR2DL4 promoter]
Azacitidine results in increased expression of KIR2DL4 mRNA; Azacitidine results in increased expression of KIR2DL4 protein
Azacitidine results in decreased methylation of KIR2DL4 promoter		 CTD PMID:18945643 NCBI chr19:54,803,610...54,814,517
Ensembl chr19:54,803,610...54,814,517 		JBrowse link
G KIR2DS4 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 increases expression EXP Azacitidine results in increased expression of KIR2DS4 mRNA CTD PMID:18945643 NCBI chr19:54,832,707...54,848,575
Ensembl chr19:54,832,676...54,848,569 		JBrowse link
G KIR3DL1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 increases expression
decreases methylation		 EXP Azacitidine results in increased expression of KIR3DL1 mRNA; Azacitidine results in increased expression of KIR3DL1 protein
Azacitidine results in decreased methylation of KIR3DL1 promoter		 CTD PMID:18945643 PMID:19394699 NCBI chr19:54,816,468...54,830,778
Ensembl chr19:54,816,468...54,830,778 		JBrowse link
G KLF6 KLF transcription factor 6 increases expression
multiple interactions		 EXP Azacitidine results in increased expression of KLF6 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]		 CTD PMID:21245298 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281 		JBrowse link
G KLK3 kallikrein related peptidase 3 increases expression EXP Azacitidine analog results in increased expression of KLK3 protein CTD PMID:18324645 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764 		JBrowse link
G KRT19 keratin 19 increases expression EXP Azacitidine results in increased expression of KRT19 mRNA CTD PMID:20823114 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308 		JBrowse link
G KRT32 keratin 32 increases expression EXP Azacitidine results in increased expression of KRT32 mRNA CTD PMID:20823114 NCBI chr17:41,459,513...41,467,386
Ensembl chr17:41,459,513...41,467,386 		JBrowse link
G KRT8 keratin 8 increases expression
multiple interactions		 EXP Azacitidine results in increased expression of KRT8 mRNA
Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]		 CTD PMID:20823114 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954 		JBrowse link
G LAMA1 laminin subunit alpha 1 affects localization ISO Azacitidine affects the localization of LAMA1 protein CTD PMID:18033690 NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797 		JBrowse link
G LAMB2 laminin subunit beta 2 increases expression EXP Azacitidine results in increased expression of LAMB2 mRNA CTD PMID:20823114 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118 		JBrowse link
G LDHB lactate dehydrogenase B increases expression EXP Azacitidine results in increased expression of LDHB mRNA CTD PMID:23437403 NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857 		JBrowse link
G LIMS1 LIM zinc finger domain containing 1 increases expression EXP Azacitidine results in increased expression of LIMS1 mRNA CTD PMID:19194470 NCBI chr 2:108,533,671...108,687,246
Ensembl chr 2:108,533,671...108,687,246 		JBrowse link
G LITAF lipopolysaccharide induced TNF factor decreases expression EXP Azacitidine results in decreased expression of LITAF mRNA CTD PMID:19194470 NCBI chr16:11,547,722...11,640,317
Ensembl chr16:11,547,722...11,636,381 		JBrowse link
G LTB4R leukotriene B4 receptor decreases expression EXP Azacitidine results in decreased expression of LTB4R mRNA CTD PMID:20823114 NCBI chr14:24,311,502...24,318,036
Ensembl chr14:24,311,450...24,318,036 		JBrowse link
G LYZ lysozyme increases expression EXP Azacitidine results in increased expression of LYZ mRNA CTD PMID:19194470 NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 decreases expression EXP Azacitidine results in decreased expression of MAD1L1 mRNA CTD PMID:19194470 NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243 		JBrowse link
G MAFB MAF bZIP transcription factor B multiple interactions
increases expression		 EXP Cisplatin affects the reaction [Azacitidine results in increased expression of MAFB mRNA] CTD PMID:36336710 NCBI chr20:40,685,848...40,689,236
Ensembl chr20:40,685,848...40,689,236 		JBrowse link
G MAGEA1 MAGE family member A1 decreases methylation
multiple interactions		 EXP Azacitidine results in decreased methylation of MAGEA1 gene
Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of MAGEA1 gene]		 CTD PMID:17686055 NCBI chr  X:153,179,284...153,183,880
Ensembl chr  X:153,179,284...153,183,880 		JBrowse link
G MAGEA3 MAGE family member A3 decreases methylation
multiple interactions
increases expression		 EXP Azacitidine results in decreased methylation of MAGEA3 promoter
[Azacitidine results in decreased methylation of MAGEA3 promoter] which results in increased expression of MAGEA3 mRNA; mocetinostat promotes the reaction [Azacitidine results in increased expression of MAGEA3 mRNA]; mocetinostat promotes the reaction [Azacitidine results in increased expression of MAGEA3 protein]
Azacitidine results in increased expression of MAGEA3 mRNA; Azacitidine results in increased expression of MAGEA3 protein		 CTD PMID:21171821 NCBI chr  X:152,698,794...152,702,347
Ensembl chr  X:152,698,767...152,702,347 		JBrowse link
G MAP1A microtubule associated protein 1A decreases expression EXP Azacitidine results in decreased expression of MAP1A mRNA CTD PMID:20823114 NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620 		JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 decreases expression EXP Azacitidine results in decreased expression of MAP2K5 mRNA CTD PMID:20823114 NCBI chr15:67,542,703...67,807,114
Ensembl chr15:67,542,703...67,807,117 		JBrowse link
G MAPT microtubule associated protein tau decreases expression EXP Azacitidine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases expression EXP 5-azacytidine decreases expression of MCL1 protein in lung cancer cells RGD PMID:24356455 RGD:153344603 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of MCM5 mRNA CTD PMID:18720364 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431 		JBrowse link
G MDC1 mediator of DNA damage checkpoint 1 increases expression EXP Azacitidine results in increased expression of MDC1 mRNA CTD PMID:20823114 NCBI chr 6:30,699,807...30,717,281
Ensembl chr 6:30,699,807...30,717,447 		JBrowse link
G MDM2 MDM2 proto-oncogene increases expression EXP Azacitidine results in increased expression of MDM2 mRNA CTD PMID:20823114 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MECP2 methyl-CpG binding protein 2 multiple interactions EXP Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103 		JBrowse link
G MEF2A myocyte enhancer factor 2A increases expression
affects expression		 ISO Azacitidine results in increased expression of MEF2A
Azacitidine affects the expression of MEF2A protein		 CTD PMID:12094073 PMID:19002953 NCBI chr15:99,565,417...99,716,488
Ensembl chr15:99,565,417...99,716,488 		JBrowse link
G MEF2D myocyte enhancer factor 2D affects expression
increases expression		 ISO Azacitidine affects the expression of MEF2D protein
Azacitidine results in increased expression of MEF2D		 CTD PMID:12094073 PMID:19002953 NCBI chr 1:156,463,727...156,500,775
Ensembl chr 1:156,463,727...156,500,779 		JBrowse link
G MEGF6 multiple EGF like domains 6 decreases expression EXP Azacitidine results in decreased expression of MEGF6 mRNA CTD PMID:19194470 NCBI chr 1:3,487,951...3,624,786
Ensembl chr 1:3,487,951...3,611,508 		JBrowse link
G MESD mesoderm development LRP chaperone decreases expression ISO Azacitidine results in decreased expression of MESD protein CTD PMID:17105402 NCBI chr15:80,946,289...80,989,819
Ensembl chr15:80,946,289...80,989,828 		JBrowse link
G MFAP2 microfibril associated protein 2 decreases expression EXP Azacitidine results in decreased expression of MFAP2 mRNA CTD PMID:20823114 NCBI chr 1:16,974,502...16,981,583
Ensembl chr 1:16,974,502...16,980,632 		JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing affects expression ISO Azacitidine affects the expression of MFGE8 mRNA CTD PMID:18033690 NCBI chr15:88,898,683...88,913,379
Ensembl chr15:88,898,683...88,913,468 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase increases expression
decreases methylation		 EXP Azacitidine results in increased expression of MGMT mRNA
Azacitidine results in decreased methylation of MGMT protein		 CTD PMID:7511991 PMID:12807730 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MIR193A microRNA 193a increases expression EXP 5-azacytidine increases expression of MIR193A in liver cells
5-azacytidine increases expression of MIR193a RNA in lung cancer cells		 RGD PMID:28036298 PMID:24356455 RGD:153344564, RGD:153344603 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR23B microRNA 23b increases expression EXP 5-azacytidine increases expression of MIR23B miRNA in liver cells RGD PMID:28036298 RGD:153344564 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304 		JBrowse link
G MIR497 microRNA 497 decreases methylation
increases expression
multiple interactions		 EXP Azacitidine results in decreased methylation of MIR497 promoter
Azacitidine results in increased expression of MIR497 mRNA
Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter]		 CTD PMID:35066776 NCBI chr17:7,017,911...7,018,022
Ensembl chr17:7,017,911...7,018,022 		JBrowse link
G MIR9-3 microRNA 9-3 increases expression EXP 5-azacytidine increases expression of MIR9-3 in lung cancer cells RGD PMID:24356455 RGD:153344603 NCBI chr15:89,368,017...89,368,106
Ensembl chr15:89,368,017...89,368,106 		JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of MKI67 mRNA CTD PMID:18720364 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP1 matrix metallopeptidase 1 increases expression EXP Azacitidine results in increased expression of MMP1 mRNA CTD PMID:20823114 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP metacept-1 inhibits the reaction [Azacitidine results in increased expression of MMP9] CTD PMID:19148494 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MORF4L2 mortality factor 4 like 2 decreases expression EXP Azacitidine results in decreased expression of MORF4L2 mRNA CTD PMID:20823114 NCBI chr  X:103,675,498...103,688,047
Ensembl chr  X:103,675,496...103,688,158 		JBrowse link
G MOV10L1 Mov10 like RNA helicase 1 increases expression EXP Azacitidine results in increased expression of MOV10L1 mRNA CTD PMID:20823114 NCBI chr22:50,090,006...50,161,687
Ensembl chr22:50,090,006...50,161,690 		JBrowse link
G MSRB2 methionine sulfoxide reductase B2 increases expression EXP Azacitidine results in increased expression of MSRB2 mRNA CTD PMID:19194470 NCBI chr10:23,095,579...23,122,013
Ensembl chr10:23,095,579...23,122,013 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression EXP Azacitidine results in decreased expression of MTHFD2 mRNA CTD PMID:20823114 NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565 		JBrowse link
G MTREX Mtr4 exosome RNA helicase increases expression EXP Azacitidine results in increased expression of MTREX mRNA CTD PMID:20823114 NCBI chr 5:55,307,989...55,425,579
Ensembl chr 5:55,307,989...55,425,579 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions		 EXP Azacitidine analog results in decreased expression of MYC mRNA
MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]		 CTD PMID:18045574 PMID:19451745 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYF5 myogenic factor 5 increases expression ISO Azacitidine results in increased expression of MYF5 mRNA CTD PMID:18938140 NCBI chr12:80,716,912...80,719,671
Ensembl chr12:80,716,912...80,719,671 		JBrowse link
G MYH7 myosin heavy chain 7 increases expression ISO Azacitidine results in increased expression of MYH7 mRNA; Azacitidine results in increased expression of MYH7 protein CTD PMID:17105402 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G MYL2 myosin light chain 2 increases expression ISO Azacitidine results in increased expression of MYL2 mRNA CTD PMID:17105402 NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,909,996...111,052,434 		JBrowse link
G MYOD1 myogenic differentiation 1 increases expression ISO Azacitidine results in increased expression of MYOD1 mRNA CTD PMID:18037191 PMID:18938140 NCBI chr11:17,719,571...17,722,136
Ensembl chr11:17,719,571...17,722,136 		JBrowse link
G MYOG myogenin increases expression ISO Azacitidine results in increased expression of MYOG mRNA CTD PMID:18938140 NCBI chr 1:203,083,129...203,086,012
Ensembl chr 1:203,083,129...203,086,012 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 increases expression ISO Azacitidine results in increased expression of NCAM1 mRNA CTD PMID:18037191 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436 		JBrowse link
G NEFL neurofilament light chain increases expression EXP Azacitidine results in increased expression of NEFL mRNA CTD PMID:20823114 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 increases expression EXP Azacitidine results in increased expression of NFATC1 mRNA CTD PMID:20823114 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NIBAN1 niban apoptosis regulator 1 increases expression
multiple interactions		 EXP Azacitidine results in increased expression of NIBAN1 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA]		 CTD PMID:21245298 NCBI chr 1:184,791,032...184,974,508
Ensembl chr 1:184,790,724...184,974,508 		JBrowse link
G NKX2-5 NK2 homeobox 5 increases expression EXP Azacitidine results in increased expression of NKX2-5 mRNA CTD PMID:18557828 NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311 		JBrowse link
G NLGN3 neuroligin 3 increases expression EXP Azacitidine results in increased expression of NLGN3 mRNA CTD PMID:20823114 NCBI chr  X:71,144,841...71,175,307
Ensembl chr  X:71,144,821...71,175,255 		JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 increases expression ISO Azacitidine results in increased expression of NME2 protein CTD PMID:17105402 NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744 		JBrowse link
G NMI N-myc and STAT interactor increases expression EXP Azacitidine results in increased expression of NMI mRNA CTD PMID:21245298 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G NNT nicotinamide nucleotide transhydrogenase increases expression EXP Azacitidine results in increased expression of NNT mRNA; Azacitidine results in increased expression of NNT protein CTD PMID:36336710 NCBI chr 5:43,602,675...43,707,396
Ensembl chr 5:43,602,692...43,707,405 		JBrowse link
G NOM1 nucleolar protein with MIF4G domain 1 decreases expression EXP Azacitidine results in decreased expression of NOM1 mRNA CTD PMID:20823114 NCBI chr 7:156,949,712...156,973,176
Ensembl chr 7:156,949,712...156,973,176 		JBrowse link
G NPHP1 nephrocystin 1 increases expression EXP Azacitidine results in increased expression of NPHP1 mRNA CTD PMID:20823114 NCBI chr 2:110,123,348...110,205,013
Ensembl chr 2:110,122,311...110,205,066 		JBrowse link
G NPPA natriuretic peptide A increases expression ISO Azacitidine results in increased expression of NPPA CTD PMID:15005238 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPB natriuretic peptide B increases expression ISO Azacitidine results in increased expression of NPPB CTD PMID:15005238 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]] CTD PMID:17682057 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions EXP [metacept-1 co-treated with Azacitidine] results in increased expression of NR4A1 CTD PMID:19148494 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NRIP1 nuclear receptor interacting protein 1 decreases expression EXP Azacitidine results in decreased expression of NRIP1 mRNA CTD PMID:20823114 NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936 		JBrowse link
G NRN1 neuritin 1 decreases expression EXP Azacitidine results in decreased expression of NRN1 mRNA CTD PMID:19194470 NCBI chr 6:5,997,999...6,007,518
Ensembl chr 6:5,997,999...6,007,605 		JBrowse link
G NT5E 5'-nucleotidase ecto increases expression EXP Azacitidine results in increased expression of NT5E mRNA CTD PMID:20823114 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791 		JBrowse link
G NTS neurotensin decreases expression EXP Azacitidine results in decreased expression of NTS mRNA CTD PMID:20823114 NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992 		JBrowse link
G NUSAP1 nucleolar and spindle associated protein 1 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of NUSAP1 mRNA CTD PMID:18720364 NCBI chr15:41,332,881...41,381,046
Ensembl chr15:41,320,794...41,381,050 		JBrowse link
G NXT2 nuclear transport factor 2 like export factor 2 increases expression EXP Azacitidine results in increased expression of NXT2 mRNA CTD PMID:19194470 NCBI chr  X:109,535,824...109,544,698
Ensembl chr  X:109,535,781...109,544,698 		JBrowse link
G OCLN occludin increases expression EXP Azacitidine results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G OGFRL1 opioid growth factor receptor like 1 increases expression EXP Azacitidine results in increased expression of OGFRL1 mRNA CTD PMID:20823114 NCBI chr 6:71,288,811...71,309,059
Ensembl chr 6:71,288,811...71,309,059 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase decreases expression
decreases methylation		 ISO Azacitidine results in decreased expression of OGG1 protein
Azacitidine results in decreased methylation of OGG1 promoter		 CTD PMID:22064374 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G OR8B8 olfactory receptor family 8 subfamily B member 8 increases expression EXP Azacitidine results in increased expression of OR8B8 mRNA CTD PMID:20823114 NCBI chr11:124,437,445...124,445,696
Ensembl chr11:124,437,445...124,445,696 		JBrowse link
G OXR1 oxidation resistance 1 increases expression EXP Azacitidine results in increased expression of OXR1 mRNA CTD PMID:20823114 NCBI chr 8:106,270,178...106,752,694
Ensembl chr 8:106,270,144...106,752,694 		JBrowse link
G OXTR oxytocin receptor decreases expression EXP Azacitidine results in decreased expression of OXTR mRNA CTD PMID:21245298 NCBI chr 3:8,741,269...8,769,613
Ensembl chr 3:8,750,381...8,769,628 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta increases expression ISO
EXP		 Azacitidine results in increased expression of P4HB protein
Azacitidine results in increased expression of P4HB mRNA		 CTD PMID:17105402 PMID:20823114 NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856 		JBrowse link
G PAEP progestagen associated endometrial protein decreases expression EXP Azacitidine results in decreased expression of PAEP mRNA CTD PMID:20823114 NCBI chr 9:135,561,756...135,566,955
Ensembl chr 9:135,561,756...135,566,955 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 increases expression EXP Azacitidine results in increased expression of PAK1 mRNA CTD PMID:20823114 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PANK3 pantothenate kinase 3 decreases expression EXP Azacitidine results in decreased expression of PANK3 mRNA CTD PMID:19194470 NCBI chr 5:168,548,495...168,579,368
Ensembl chr 5:168,548,495...168,579,368 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO Azacitidine results in increased cleavage of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]		 CTD PMID:32278510 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PAX4 paired box 4 increases expression EXP Azacitidine results in increased expression of PAX4 mRNA CTD PMID:18949370 NCBI chr 7:127,610,292...127,618,142
Ensembl chr 7:127,610,292...127,618,142 		JBrowse link
G PCDH18 protocadherin 18 decreases expression EXP Azacitidine results in decreased expression of PCDH18 mRNA CTD PMID:20823114 NCBI chr 4:137,518,918...137,532,494
Ensembl chr 4:137,518,918...137,532,494 		JBrowse link
G PCDHA1 protocadherin alpha 1 affects methylation ISO Azacitidine affects the methylation of PCDHA1 promoter CTD PMID:18204046 NCBI chr 5:140,786,136...141,012,347
Ensembl chr 5:140,786,136...141,012,347 		JBrowse link
G PCDHA10 protocadherin alpha 10 affects methylation ISO Azacitidine affects the methylation of PCDHA10 promoter CTD PMID:18204046 NCBI chr 5:140,855,897...141,012,347
Ensembl chr 5:140,855,883...141,012,347 		JBrowse link
G PCDHA11 protocadherin alpha 11 affects methylation ISO Azacitidine affects the methylation of PCDHA11 promoter CTD PMID:18204046 NCBI chr 5:140,867,513...141,012,347
Ensembl chr 5:140,868,183...141,012,347 		JBrowse link
G PCDHA2 protocadherin alpha 2 affects methylation ISO Azacitidine affects the methylation of PCDHA2 promoter CTD PMID:18204046 NCBI chr 5:140,794,852...141,012,347
Ensembl chr 5:140,794,852...141,012,347 		JBrowse link
G PCDHA3 protocadherin alpha 3 affects methylation ISO Azacitidine affects the methylation of PCDHA3 promoter CTD PMID:18204046 NCBI chr 5:140,801,057...141,012,347
Ensembl chr 5:140,801,028...141,012,347 		JBrowse link
G PCDHA4 protocadherin alpha 4 affects methylation ISO Azacitidine affects the methylation of PCDHA4 promoter CTD PMID:18204046 NCBI chr 5:140,807,068...141,012,347
Ensembl chr 5:140,807,037...141,012,347 		JBrowse link
G PCDHA5 protocadherin alpha 5 affects methylation ISO Azacitidine affects the methylation of PCDHA5 promoter CTD PMID:18204046 NCBI chr 5:140,821,613...141,012,347
Ensembl chr 5:140,821,604...141,012,347 		JBrowse link
G PCDHA6 protocadherin alpha 6 affects methylation ISO Azacitidine affects the methylation of PCDHA6 promoter CTD PMID:18204046 NCBI chr 5:140,827,960...141,012,347
Ensembl chr 5:140,827,958...141,012,347 		JBrowse link
G PCDHA7 protocadherin alpha 7 affects methylation ISO Azacitidine affects the methylation of PCDHA7 promoter CTD PMID:18204046 NCBI chr 5:140,834,269...141,012,347
Ensembl chr 5:140,834,248...141,012,347 		JBrowse link
G PCDHA9 protocadherin alpha 9 affects methylation ISO Azacitidine affects the methylation of PCDHA8 promoter; Azacitidine affects the methylation of PCDHA9 promoter CTD PMID:18204046 NCBI chr 5:140,847,772...141,012,347
Ensembl chr 5:140,847,772...141,012,347 		JBrowse link
G PCDHB14 protocadherin beta 14 decreases expression EXP Azacitidine results in decreased expression of PCDHB14 mRNA CTD PMID:20823114 NCBI chr 5:141,223,343...141,227,759
Ensembl chr 5:141,223,343...141,227,759 		JBrowse link
G PCDHB4 protocadherin beta 4 decreases expression EXP Azacitidine results in decreased expression of PCDHB4 mRNA CTD PMID:20823114 NCBI chr 5:141,121,818...141,125,623
Ensembl chr 5:141,121,818...141,125,623 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression
multiple interactions		 ISO Azacitidine results in decreased expression of PCNA protein
[Cisplatin co-treated with Azacitidine] results in decreased expression of PCNA protein		 CTD PMID:19723570 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 increases expression EXP Azacitidine results in increased expression of PDK1 mRNA CTD PMID:20823114 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression
decreases methylation		 EXP Azacitidine results in increased expression of PDK4 protein
Azacitidine results in decreased methylation of PDK4 promoter		 CTD PMID:28003426 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 increases expression ISO Azacitidine results in increased expression of PECAM1 mRNA CTD PMID:18037191 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PFN1 profilin 1 increases expression EXP Azacitidine results in increased expression of PFN1 mRNA CTD PMID:20823114 NCBI chr17:4,945,652...4,948,530
Ensembl chr17:4,945,652...4,949,061 		JBrowse link
G PHACTR2 phosphatase and actin regulator 2 increases expression EXP Azacitidine results in increased expression of PHACTR2 mRNA CTD PMID:20823114 NCBI chr 6:143,536,878...143,831,185
Ensembl chr 6:143,536,845...143,831,185 		JBrowse link
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha decreases expression EXP Azacitidine results in decreased expression of PIP5K1A mRNA CTD PMID:19194470 NCBI chr 1:151,195,419...151,249,531
Ensembl chr 1:151,197,949...151,249,536 		JBrowse link
G PITPNC1 phosphatidylinositol transfer protein cytoplasmic 1 decreases expression EXP Azacitidine results in decreased expression of PITPNC1 mRNA CTD PMID:20823114 NCBI chr17:67,377,281...67,697,256
Ensembl chr17:67,377,281...67,697,256 		JBrowse link
G PITX3 paired like homeodomain 3 increases expression ISO Azacitidine results in increased expression of PITX3 mRNA CTD PMID:27415467 NCBI chr10:102,230,189...102,241,512
Ensembl chr10:102,230,189...102,241,512 		JBrowse link
G PJA1 praja ring finger ubiquitin ligase 1 increases expression EXP Azacitidine results in increased expression of PJA1 mRNA CTD PMID:19194470 NCBI chr  X:69,160,746...69,165,453
Ensembl chr  X:69,160,851...69,165,521 		JBrowse link
G PKD2L1 polycystin 2 like 1, transient receptor potential cation channel increases expression EXP Azacitidine results in increased expression of PKD2L1 mRNA CTD PMID:20823114 NCBI chr10:100,288,149...100,330,228
Ensembl chr10:100,288,149...100,330,264 		JBrowse link
G PKM pyruvate kinase M1/2 increases expression EXP Azacitidine results in increased expression of PKM mRNA CTD PMID:20823114 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PLCB1 phospholipase C beta 1 decreases methylation
decreases response to substance
increases response to substance
increases expression		 EXP Azacitidine results in decreased methylation of PLCB1 promoter
PLCB1 promoter modified form results in decreased susceptibility to Azacitidine
PLCB1 mRNA results in increased susceptibility to Azacitidine; PLCB1 protein results in increased susceptibility to Azacitidine
Azacitidine results in increased expression of PLCB1 mRNA; Azacitidine results in increased expression of PLCB1 protein		 CTD PMID:19805378 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360 		JBrowse link
G PLPP1 phospholipid phosphatase 1 increases expression EXP Azacitidine results in increased expression of PLPP1 mRNA CTD PMID:19194470 NCBI chr 5:55,424,854...55,534,964
Ensembl chr 5:55,424,854...55,534,969 		JBrowse link
G PLS3 plastin 3 decreases expression EXP Azacitidine results in decreased expression of PLS3 mRNA CTD PMID:20823114 NCBI chr  X:115,561,174...115,650,861
Ensembl chr  X:115,561,174...115,650,861 		JBrowse link
G PML PML nuclear body scaffold increases expression EXP Azacitidine results in increased expression of PML mRNA CTD PMID:19194470 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases methylation
increases expression		 ISO Azacitidine results in decreased methylation of PPARG promoter
Azacitidine results in increased expression of PPARG mRNA		 CTD PMID:19589179 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha multiple interactions
increases expression
decreases methylation		 EXP Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter]
Azacitidine results in increased expression of PPP2CA mRNA
Azacitidine results in decreased methylation of PPP2CA promoter		 CTD PMID:19155497 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PRDX4 peroxiredoxin 4 decreases expression ISO Azacitidine results in decreased expression of PRDX4 protein CTD PMID:17105402 NCBI chr  X:23,667,493...23,686,397
Ensembl chr  X:23,664,262...23,686,397 		JBrowse link
G PRF1 perforin 1 multiple interactions EXP Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759 		JBrowse link
G PRL prolactin multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein CTD PMID:20823114 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PROM1 prominin 1 increases expression ISO Azacitidine results in increased expression of PROM1 mRNA CTD PMID:18037191 NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378 		JBrowse link
G PRSS12 serine protease 12 decreases expression EXP Azacitidine results in decreased expression of PRSS12 mRNA CTD PMID:20823114 NCBI chr 4:118,280,038...118,353,003
Ensembl chr 4:118,280,038...118,353,003 		JBrowse link
G PSEN1 presenilin 1 decreases methylation
multiple interactions		 ISO Azacitidine results in decreased methylation of PSEN1 promoter
Betaine inhibits the reaction [Azacitidine results in decreased methylation of PSEN1 promoter]		 CTD PMID:19635394 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSG1 pregnancy specific beta-1-glycoprotein 1 increases expression EXP Azacitidine results in increased expression of PSG1 mRNA CTD PMID:20823114 NCBI chr19:42,866,464...42,879,713
Ensembl chr19:42,866,464...42,879,822 		JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions EXP Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter] CTD PMID:22841775 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTHLH parathyroid hormone like hormone decreases expression EXP Azacitidine results in decreased expression of PTHLH mRNA CTD PMID:20823114 NCBI chr12:27,958,084...27,972,733
Ensembl chr12:27,958,084...27,972,733 		JBrowse link
G PTPA protein phosphatase 2 phosphatase activator increases expression EXP Azacitidine results in increased expression of PTPA mRNA CTD PMID:20823114 NCBI chr 9:129,110,950...129,148,946
Ensembl chr 9:129,110,950...129,148,946 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C increases expression EXP Azacitidine results in increased expression of PTPRC mRNA CTD PMID:19194470 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,757,476 		JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O increases expression ISO Azacitidine results in increased expression of PTPRO mRNA CTD PMID:14508512 NCBI chr12:15,322,508...15,598,331
Ensembl chr12:15,322,257...15,602,175 		JBrowse link
G RAB13 RAB13, member RAS oncogene family decreases methylation EXP Azacitidine results in decreased methylation of RAB13 promoter CTD PMID:19194470 NCBI chr 1:153,981,650...153,990,708
Ensembl chr 1:153,981,617...153,986,358 		JBrowse link
G RAB1B RAB1B, member RAS oncogene family increases expression EXP Azacitidine results in increased expression of RAB1B mRNA CTD PMID:20823114 NCBI chr11:66,268,639...66,277,492
Ensembl chr11:66,268,590...66,277,492 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 increases expression EXP Azacitidine results in increased expression of RACGAP1 mRNA CTD PMID:20823114 NCBI chr12:49,989,162...50,033,440
Ensembl chr12:49,976,923...50,033,136 		JBrowse link
G RANBP2 RAN binding protein 2 increases expression EXP Azacitidine results in increased expression of RANBP2 mRNA CTD PMID:19194470 NCBI chr 2:108,719,482...109,842,301
Ensembl chr 2:108,719,482...108,785,810 		JBrowse link
G RASA3 RAS p21 protein activator 3 increases expression EXP Azacitidine results in increased expression of RASA3 mRNA CTD PMID:20823114 NCBI chr13:113,977,783...114,132,623
Ensembl chr13:113,977,783...114,132,623 		JBrowse link
G RCN1 reticulocalbin 1 decreases expression EXP Azacitidine results in decreased expression of RCN1 mRNA CTD PMID:20823114 NCBI chr11:32,091,074...32,105,722
Ensembl chr11:32,091,074...32,105,722 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit affects localization
decreases expression 		EXP Azacitidine affects the localization of RELA protein
5-azacytidine decreases expression of RELA protein in lung cancer cells		 CTD
RGD		 PMID:18443271 PMID:24356455 RGD:153344603 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RET ret proto-oncogene decreases expression EXP Azacitidine results in decreased expression of RET mRNA CTD PMID:20823114 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G RFC3 replication factor C subunit 3 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of RFC3 mRNA CTD PMID:18720364 NCBI chr13:33,818,149...33,977,377
Ensembl chr13:33,818,069...33,966,558 		JBrowse link
G RHOB ras homolog family member B multiple interactions EXP [trichostatin A co-treated with Azacitidine] results in increased expression of RHOB protein; Azacitidine promotes the reaction [trichostatin A results in increased expression of RHOB mRNA] CTD PMID:18047684 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440 		JBrowse link
G RIN1 Ras and Rab interactor 1 increases expression EXP Azacitidine results in increased expression of RIN1 mRNA CTD PMID:20823114 NCBI chr11:66,330,241...66,336,774
Ensembl chr11:66,330,241...66,336,840 		JBrowse link
G RPL5P29 ribosomal protein L5 pseudogene 29 decreases expression EXP Azacitidine results in decreased expression of RPL5P29 mRNA CTD PMID:20823114 NCBI chr11:56,357,273...56,358,282
Ensembl chr11:56,357,328...56,358,221 		JBrowse link
G RPP21 ribonuclease P/MRP subunit p21 increases expression EXP Azacitidine results in increased expression of RPP21 mRNA CTD PMID:20823114 NCBI chr 6:30,345,156...30,346,857
Ensembl chr 6:30,345,131...30,346,884 		JBrowse link
G RPS6 ribosomal protein S6 decreases phosphorylation EXP Azacitidine results in decreased phosphorylation of RPS6 protein CTD PMID:21245298 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPSA ribosomal protein SA decreases expression EXP Azacitidine results in decreased expression of RPSA mRNA CTD PMID:20823114 NCBI chr 3:39,406,720...39,412,542
Ensembl chr 3:39,406,716...39,426,255 		JBrowse link
G RPSAP12 ribosomal protein SA pseudogene 12 decreases expression EXP Azacitidine results in decreased expression of RPSAP12 mRNA CTD PMID:20823114 NCBI chr12:68,552,925...68,553,958
Ensembl chr12:68,552,995...68,553,882 		JBrowse link
G RPSAP28 ribosomal protein SA pseudogene 28 decreases expression EXP Azacitidine results in decreased expression of RPSAP28 mRNA CTD PMID:20823114 NCBI chr 2:73,369,951...73,370,963
Ensembl chr 2:73,370,019...73,370,892 		JBrowse link
G RPSAP3 ribosomal protein SA pseudogene 3 decreases expression EXP Azacitidine results in decreased expression of RPSAP3 mRNA CTD PMID:20823114 NCBI chr14:76,634,705...76,635,737
Ensembl chr14:76,634,775...76,635,661 		JBrowse link
G RPSAP31 ribosomal protein SA pseudogene 31 decreases expression EXP Azacitidine results in decreased expression of RPSAP31 mRNA CTD PMID:20823114 NCBI chr 3:183,887,522...183,888,537
Ensembl chr 3:183,887,555...183,888,449 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA CTD PMID:18720364 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression EXP Azacitidine results in increased expression of RRM2B mRNA CTD PMID:19010910 NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961 		JBrowse link
G RUNX1 RUNX family transcription factor 1 multiple interactions EXP Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX3 RUNX family transcription factor 3 affects methylation EXP Azacitidine affects the methylation of RUNX3 gene CTD PMID:18058463 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G S100A14 S100 calcium binding protein A14 decreases expression EXP Azacitidine results in decreased expression of S100A14 mRNA CTD PMID:20823114 NCBI chr 1:153,614,255...153,616,325
Ensembl chr 1:153,614,255...153,616,986 		JBrowse link
G S100A9 S100 calcium binding protein A9 increases expression EXP Azacitidine results in increased expression of S100A9 mRNA CTD PMID:19194470 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G S100P S100 calcium binding protein P increases expression EXP Azacitidine results in increased expression of S100P mRNA CTD PMID:19194470 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170 		JBrowse link
G SALL4 spalt like transcription factor 4 affects methylation EXP Azacitidine affects the methylation of SALL4 promoter CTD PMID:17546590 NCBI chr20:51,782,331...51,802,521
Ensembl chr20:51,782,331...51,802,521 		JBrowse link
G SCAMP4 secretory carrier membrane protein 4 increases expression EXP Azacitidine results in increased expression of SCAMP4 mRNA CTD PMID:20823114 NCBI chr19:1,905,399...1,926,013
Ensembl chr19:1,905,214...1,926,013 		JBrowse link
G SDCBP syndecan binding protein decreases expression EXP Azacitidine results in decreased expression of SDCBP mRNA CTD PMID:20823114 NCBI chr 8:58,553,261...58,582,858
Ensembl chr 8:58,552,924...58,582,859 		JBrowse link
G SEMA3A semaphorin 3A increases expression EXP Azacitidine results in increased expression of SEMA3A mRNA CTD PMID:20823114 NCBI chr 7:83,955,777...84,492,725
Ensembl chr 7:83,955,777...84,492,724 		JBrowse link
G SEMA6C semaphorin 6C increases expression EXP Azacitidine results in increased expression of SEMA6C mRNA CTD PMID:20823114 NCBI chr 1:151,131,685...151,146,631
Ensembl chr 1:151,131,685...151,146,631 		JBrowse link
G SENP3 SUMO specific peptidase 3 increases expression EXP Azacitidine results in increased expression of SENP3 mRNA CTD PMID:20823114 NCBI chr17:7,561,919...7,571,969
Ensembl chr17:7,561,919...7,571,969 		JBrowse link
G SIRPB1 signal regulatory protein beta 1 decreases expression EXP Azacitidine results in decreased expression of SIRPB1 mRNA CTD PMID:20823114 NCBI chr20:1,561,385...1,620,009
Ensembl chr20:1,561,385...1,620,061 		JBrowse link
G SIX2 SIX homeobox 2 multiple interactions
decreases expression		 EXP Cisplatin affects the reaction [Azacitidine results in decreased expression of SIX2 mRNA] CTD PMID:36336710 NCBI chr 2:45,005,182...45,009,452
Ensembl chr 2:45,005,182...45,009,452 		JBrowse link
G SLBP stem-loop histone mRNA binding protein multiple interactions EXP Azacitidine inhibits the reaction [sodium arsenite results in decreased expression of SLBP mRNA] CTD PMID:25266719 NCBI chr 4:1,692,731...1,712,319
Ensembl chr 4:1,692,731...1,712,344 		JBrowse link
G SLC28A1 solute carrier family 28 member 1 increases response to substance
multiple interactions
increases uptake		 EXP SLC28A1 protein results in increased susceptibility to Azacitidine
[SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Sodium affects the reaction [SLC28A1 protein results in increased uptake of Azacitidine]		 CTD PMID:19139132 NCBI chr15:84,884,662...84,975,649
Ensembl chr15:84,884,654...84,945,798 		JBrowse link
G SLC29A2 solute carrier family 29 member 2 decreases expression EXP Azacitidine results in decreased expression of SLC29A2 mRNA CTD PMID:19194470 NCBI chr11:66,362,521...66,372,446
Ensembl chr11:66,362,521...66,372,214 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 multiple interactions
increases expression		 EXP [Azacitidine co-treated with Butyrates] affects the expression of SLC5A5 mRNA
Azacitidine results in increased expression of SLC5A5 mRNA		 CTD PMID:16954431 PMID:17164311 NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174 		JBrowse link
G SNU13 small nuclear ribonucleoprotein 13 increases expression EXP Azacitidine results in increased expression of SNU13 mRNA CTD PMID:20823114 NCBI chr22:41,673,933...41,690,480
Ensembl chr22:41,673,933...41,690,504 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 affects expression EXP Azacitidine affects the expression of SOCS3 protein CTD PMID:18443271 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOX13 SRY-box transcription factor 13 decreases expression EXP Azacitidine results in decreased expression of SOX13 mRNA CTD PMID:20823114 NCBI chr 1:204,073,115...204,127,743
Ensembl chr 1:204,073,115...204,127,743 		JBrowse link
G SOX2 SRY-box transcription factor 2 increases expression ISO Azacitidine results in increased expression of SOX2 mRNA CTD PMID:27415467 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SOX8 SRY-box transcription factor 8 decreases expression ISO Azacitidine results in decreased expression of SOX8 mRNA CTD PMID:18033690 NCBI chr16:981,770...986,979
Ensembl chr16:981,444...986,979 		JBrowse link
G SOX9 SRY-box transcription factor 9 affects expression ISO Azacitidine affects the expression of SOX9 mRNA CTD PMID:18033690 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions
decreases expression		 EXP
ISO		 Azacitidine promotes the reaction [SP1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [SP1 protein binds to KIR2DL4 promoter]
Azacitidine results in decreased expression of SP1 mRNA
Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]		 CTD PMID:17198683 PMID:18945643 PMID:20823114 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SP7 Sp7 transcription factor increases expression ISO Azacitidine results in increased expression of SP7 mRNA CTD PMID:17085970 NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315 		JBrowse link
G SPAG5 sperm associated antigen 5 multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of SPAG5 mRNA CTD PMID:18720364 NCBI chr17:28,577,574...28,599,025
Ensembl chr17:28,577,565...28,599,025 		JBrowse link
G SRPX sushi repeat containing protein X-linked decreases expression EXP Azacitidine results in decreased expression of SRPX mRNA CTD PMID:19194470 NCBI chr  X:38,149,339...38,220,871
Ensembl chr  X:38,149,336...38,220,924 		JBrowse link
G SRSF7 serine and arginine rich splicing factor 7 decreases expression EXP Azacitidine results in decreased expression of SRSF7 mRNA CTD PMID:20823114 NCBI chr 2:38,743,599...38,751,494
Ensembl chr 2:38,743,599...38,751,494 		JBrowse link
G SSX2IP SSX family member 2 interacting protein increases expression EXP Azacitidine results in increased expression of SSX2IP mRNA CTD PMID:20823114 NCBI chr 1:84,643,706...84,690,745
Ensembl chr 1:84,643,706...84,690,803 		JBrowse link
G ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 increases expression EXP Azacitidine results in increased expression of ST3GAL6 mRNA CTD PMID:19194470 NCBI chr 3:98,732,262...98,795,852
Ensembl chr 3:98,732,236...98,821,201 		JBrowse link
G ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 decreases expression EXP Azacitidine results in decreased expression of ST8SIA2 mRNA CTD PMID:20823114 NCBI chr15:92,393,881...92,468,728
Ensembl chr15:92,393,881...92,468,728 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions EXP [Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein CTD PMID:18443271 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STC2 stanniocalcin 2 decreases expression EXP Azacitidine results in decreased expression of STC2 mRNA CTD PMID:19194470 NCBI chr 5:173,314,723...173,328,414
Ensembl chr 5:173,314,723...173,328,447 		JBrowse link
G STK38 serine/threonine kinase 38 decreases expression EXP Azacitidine results in decreased expression of STK38 mRNA CTD PMID:20823114 NCBI chr 6:36,493,892...36,547,479
Ensembl chr 6:36,493,892...36,547,479 		JBrowse link
G SULF1 sulfatase 1 decreases expression EXP Azacitidine results in decreased expression of SULF1 mRNA CTD PMID:20823114 NCBI chr 8:69,466,781...69,660,912
Ensembl chr 8:69,466,624...69,660,915 		JBrowse link
G SULT1C2 sulfotransferase family 1C member 2 increases expression EXP Azacitidine results in increased expression of SULT1C2 mRNA CTD PMID:19194470 NCBI chr 2:108,288,895...108,309,915
Ensembl chr 2:108,288,639...108,309,915 		JBrowse link
G TAT tyrosine aminotransferase increases expression EXP Azacitidine results in increased expression of TAT mRNA CTD PMID:27590069 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092 		JBrowse link
G TBC1D4 TBC1 domain family member 4 decreases expression EXP Azacitidine results in decreased expression of TBC1D4 mRNA CTD PMID:19194470 NCBI chr13:75,283,503...75,482,169
Ensembl chr13:75,283,503...75,482,169 		JBrowse link
G TCEA1 transcription elongation factor A1 decreases expression EXP Azacitidine results in decreased expression of TCEA1 mRNA CTD PMID:20823114 NCBI chr 8:53,966,556...54,022,448
Ensembl chr 8:53,966,552...54,022,448 		JBrowse link
G TECPR2 tectonin beta-propeller repeat containing 2 increases expression EXP Azacitidine results in increased expression of TECPR2 mRNA CTD PMID:19194470 NCBI chr14:102,362,941...102,502,477
Ensembl chr14:102,362,941...102,502,477 		JBrowse link
G TEK TEK receptor tyrosine kinase increases expression ISO Azacitidine results in increased expression of TEK mRNA CTD PMID:18037191 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174 		JBrowse link
G TERT telomerase reverse transcriptase decreases expression
multiple interactions
decreases methylation
decreases activity		 EXP Azacitidine analog results in decreased expression of TERT mRNA; Azacitidine results in decreased expression of TERT mRNA
E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]; MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
Azacitidine results in decreased methylation of TERT promoter		 CTD PMID:18045574 PMID:19451745 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 increases expression EXP Azacitidine results in increased expression of TFE3 mRNA CTD PMID:19194470 NCBI chr  X:49,028,726...49,043,357
Ensembl chr  X:49,028,726...49,043,410 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO
EXP		 [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein
Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter]; Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]		 CTD PMID:18493985 PMID:22841775 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G THUMPD1 THUMP domain containing 1 increases expression EXP Azacitidine results in increased expression of THUMPD1 mRNA CTD PMID:19194470 NCBI chr16:20,733,664...20,741,818
Ensembl chr16:20,702,816...20,742,084 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression EXP Azacitidine results in increased expression of TIMP1 mRNA CTD PMID:20823114 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TJP1 tight junction protein 1 increases expression EXP Azacitidine results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TMED3 transmembrane p24 trafficking protein 3 increases expression EXP Azacitidine results in increased expression of TMED3 mRNA CTD PMID:20823114 NCBI chr15:79,311,112...79,413,886
Ensembl chr15:79,311,112...79,427,432 		JBrowse link
G TMPO thymopoietin multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of TMPO mRNA CTD PMID:18720364 NCBI chr12:98,515,573...98,550,351
Ensembl chr12:98,515,579...98,550,351 		JBrowse link
G TNC tenascin C decreases expression EXP Azacitidine results in decreased expression of TNC mRNA CTD PMID:20823114 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TNF tumor necrosis factor increases expression
increases response to substance		 ISO
EXP		 Azacitidine results in increased expression of TNF mRNA
Azacitidine results in increased susceptibility to TNF protein		 CTD PMID:17156202 PMID:18829727 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF10 TNF superfamily member 10 increases response to substance EXP
ISO		 Azacitidine results in increased susceptibility to TNFSF10 protein CTD PMID:18829727 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TNNI3 troponin I3, cardiac type increases expression ISO Azacitidine results in increased expression of TNNI3 protein CTD PMID:17105402 NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773 		JBrowse link
G TNNT2 troponin T2, cardiac type increases expression ISO Azacitidine results in increased expression of TNNT2 protein CTD PMID:22496879 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764 		JBrowse link
G TOP2A DNA topoisomerase II alpha multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of TOP2A mRNA; [Curcumin co-treated with Azacitidine] results in decreased expression of TOP2A mRNA CTD PMID:18348204 PMID:18720364 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TP53 tumor protein p53 affects activity EXP Azacitidine affects the activity of TP53 protein CTD PMID:35435491 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP73 tumor protein p73 multiple interactions EXP TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA] CTD PMID:21245298 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
G TPD52 tumor protein D52 increases expression ISO Azacitidine results in increased expression of TPD52 mRNA CTD PMID:27415467 NCBI chr 8:80,031,082...80,171,564
Ensembl chr 8:80,034,745...80,231,232 		JBrowse link
G TPM2 tropomyosin 2 increases expression EXP Azacitidine results in increased expression of TPM2 mRNA CTD PMID:20823114 NCBI chr 9:35,681,993...35,690,056
Ensembl chr 9:35,681,992...35,690,056 		JBrowse link
G TPO thyroid peroxidase increases expression EXP Azacitidine results in increased expression of TPO mRNA CTD PMID:17679169 NCBI chr 2:1,374,047...1,543,673
Ensembl chr 2:1,374,066...1,543,711 		JBrowse link
G TPSG1 tryptase gamma 1 decreases expression EXP Azacitidine results in decreased expression of TPSG1 mRNA CTD PMID:20823114 NCBI chr16:1,221,651...1,225,268
Ensembl chr16:1,221,651...1,225,793 		JBrowse link
G TRH thyrotropin releasing hormone decreases expression EXP Azacitidine results in decreased expression of TRH mRNA CTD PMID:19194470 NCBI chr 3:129,974,720...129,977,935
Ensembl chr 3:129,974,688...129,977,935 		JBrowse link
G TRIB1 tribbles pseudokinase 1 decreases expression EXP Azacitidine results in decreased expression of TRIB1 mRNA CTD PMID:19194470 NCBI chr 8:125,430,358...125,438,403
Ensembl chr 8:125,430,358...125,438,403 		JBrowse link
G TRIM8 tripartite motif containing 8 increases expression EXP Azacitidine results in increased expression of TRIM8 mRNA CTD PMID:19194470 NCBI chr10:102,644,479...102,658,319
Ensembl chr10:102,642,503...102,658,318 		JBrowse link
G TSC1 TSC complex subunit 1 multiple interactions EXP [Azacitidine affects the methylation of TSC1 promoter] which affects the expression of TSC1 mRNA CTD PMID:18538015 NCBI chr 9:132,891,349...132,945,378
Ensembl chr 9:132,891,348...132,946,874 		JBrowse link
G TSC2 TSC complex subunit 2 decreases methylation
multiple interactions
increases expression		 EXP Azacitidine results in decreased methylation of TSC2 promoter
[Azacitidine affects the methylation of TSC2 promoter] which affects the expression of TSC2 mRNA
Azacitidine results in increased expression of TSC2 mRNA		 CTD PMID:18538015 PMID:19250671 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
G TSHR thyroid stimulating hormone receptor increases expression EXP Azacitidine results in increased expression of TSHR mRNA CTD PMID:17679169 NCBI chr14:80,955,621...81,146,306
Ensembl chr14:80,954,989...81,146,306 		JBrowse link
G TSPAN32 tetraspanin 32 decreases expression EXP Azacitidine results in decreased expression of TSPAN32 mRNA CTD PMID:19194470 NCBI chr11:2,302,013...2,318,204
Ensembl chr11:2,301,997...2,318,204 		JBrowse link
G TTK TTK protein kinase multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of TTK mRNA CTD PMID:18720364 NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C multiple interactions EXP [Azacitidine co-treated with Thalidomide] affects the expression of UBE2C mRNA CTD PMID:18720364 NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957 		JBrowse link
G UHMK1 U2AF homology motif kinase 1 increases expression EXP Azacitidine results in increased expression of UHMK1 mRNA CTD PMID:20823114 NCBI chr 1:162,497,174...162,529,631
Ensembl chr 1:162,497,251...162,529,631 		JBrowse link
G USH2A usherin increases expression EXP Azacitidine results in increased expression of USH2A mRNA CTD PMID:20823114 NCBI chr 1:215,622,891...216,423,448
Ensembl chr 1:215,622,891...216,423,448 		JBrowse link
G USHBP1 USH1 protein network component harmonin binding protein 1 decreases expression EXP Azacitidine results in decreased expression of USHBP1 mRNA CTD PMID:20823114 NCBI chr19:17,249,171...17,264,745
Ensembl chr19:17,249,171...17,282,786 		JBrowse link
G VIM vimentin decreases expression
increases expression
multiple interactions		 ISO
EXP		 Azacitidine results in decreased expression of VIM protein
Azacitidine results in increased expression of VIM mRNA; Azacitidine results in increased expression of VIM protein
[Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein		 CTD PMID:17105402 PMID:20823114 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G WDR47 WD repeat domain 47 decreases expression EXP Azacitidine results in decreased expression of WDR47 mRNA CTD PMID:19194470 NCBI chr 1:108,970,214...109,042,102
Ensembl chr 1:108,970,214...109,042,113 		JBrowse link
G WNT10B Wnt family member 10B increases expression ISO Azacitidine results in increased expression of WNT10B mRNA CTD PMID:27415467 NCBI chr12:48,965,340...48,971,735
Ensembl chr12:48,965,340...48,971,735 		JBrowse link
G WNT5A Wnt family member 5A increases expression EXP Azacitidine results in increased expression of WNT5A mRNA CTD PMID:20823114 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G WWTR1 WW domain containing transcription regulator 1 increases expression EXP Azacitidine results in increased expression of WWTR1 mRNA CTD PMID:20823114 NCBI chr 3:149,517,235...149,724,788
Ensembl chr 3:149,517,235...149,736,714 		JBrowse link
G XAF1 XIAP associated factor 1 decreases methylation
increases expression
decreases expression		 EXP Azacitidine results in decreased methylation of XAF1 promoter
Azacitidine results in increased expression of XAF1 mRNA; Azacitidine results in increased expression of XAF1 protein
Azacitidine results in decreased expression of XAF1 mRNA alternative form		 CTD PMID:19077051 PMID:19549372 NCBI chr17:6,755,447...6,775,647
Ensembl chr17:6,755,447...6,775,647 		JBrowse link
G ZFP64 ZFP64 zinc finger protein affects methylation EXP Azacitidine affects the methylation of ZFP64 promoter CTD PMID:17546590 NCBI chr20:52,084,011...52,191,779
Ensembl chr20:52,051,663...52,204,308 		JBrowse link
G ZNF189 zinc finger protein 189 decreases expression EXP Azacitidine results in decreased expression of ZNF189 mRNA CTD PMID:20823114 NCBI chr 9:101,398,851...101,410,654
Ensembl chr 9:101,398,851...101,410,660 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 increases expression EXP Azacitidine results in increased expression of ZP3 mRNA CTD PMID:20823114 NCBI chr 7:76,397,522...76,442,069
Ensembl chr 7:76,397,518...76,442,071 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26050
    role 25966
      application 25188
        pharmaceutical 24562
          drug 24559
            antineoplastic agent 20861
              5-azacytidine 427
Path 2
Term Annotations click to browse term
  CHEBI ontology 26050
    subatomic particle 26025
      composite particle 26025
        hadron 26025
          baryon 26025
            nucleon 26025
              atomic nucleus 26025
                atom 26025
                  main group element atom 25850
                    p-block element atom 25850
                      carbon group element atom 25447
                        carbon atom 25405
                          organic molecular entity 25405
                            heteroorganic entity 24781
                              organochalcogen compound 24394
                                organooxygen compound 24071
                                  carbohydrates and carbohydrate derivatives 16786
                                    carbohydrate 16786
                                      monosaccharide 4977
                                        aldose 3330
                                          aldopentose 791
                                            ribose 789
                                              D-ribose 787
                                                D-ribofuranose 787
                                                  beta-D-ribose 428
                                                    5-azacytidine 427
paths to the root