Gene: MCM5 (minichromosome maintenance complex component 5)  Homo sapiens

Symbol: MCM5
Name: minichromosome maintenance complex component 5
Description: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC46; CDC46 homolog; DNA replication licensing factor MCM5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (s. cerevisiae); MGC5315; minichromosome maintenance deficient 5 (cell division cycle 46); OTTHUMP00000198814; OTTHUMP00000198821; P1-CDC46
Orthologs: Mus musculus : Mcm5 (minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae))  MGI
Rattus norvegicus : Mcm5 (minichromosome maintenance complex component 5)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_12219,717,145 - 19,741,597+NCBI
Human Genome Assembly HuRef2218,756,625 - 18,781,112+NCBI
Human Genome Assembly GRCh372235,796,116 - 35,820,495+NCBI
Human Genome Assembly Build 362234,126,116 - 34,150,495+NCBI
Human Cytogenetic Map22q13.1 NCBI
Human Genome Assembly2234,120,681 - 34,145,048 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on MCM5
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1315334
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-03-12
Status: ACTIVE