Gene: TRH (thyrotropin-releasing hormone)  Homo sapiens

Symbol: TRH
Name: thyrotropin-releasing hormone
Description: This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC125964; MGC125965; OTTHUMP00000216039; OTTHUMP00000216040; prothyroliberin; protirelin; thyrotropin releasing hormone; thyrotropin-releasing factor; TRF; TSH-releasing factor
Orthologs: Mus musculus : Trh (thyrotropin releasing hormone)  MGI
Rattus norvegicus : Trh (thyrotropin releasing hormone)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_13129,676,835 - 129,680,500+NCBI
Human Genome Assembly HuRef3127,076,442 - 127,080,106+NCBI
Human Genome Assembly GRCh373129,693,114 - 129,696,778+NCBI
Human Genome Assembly Build 363131,176,253 - 131,179,470+NCBI
Human Cytogenetic Map3q13.3-q21 NCBI
Human Genome Assembly3131,176,260 - 131,179,478 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on TRH
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 69154
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2013-05-07
Status: ACTIVE