Gene: RRM2 (ribonucleotide reductase M2)  Homo sapiens

Symbol: RRM2
Name: ribonucleotide reductase M2
Description: This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: OTTHUMP00000115511; OTTHUMP00000214026; OTTHUMP00000220215; R2; ribonucleoside-diphosphate reductase subunit M2; ribonucleotide reductase m2; ribonucleotide reductase M2 polypeptide; ribonucleotide reductase small chain; ribonucleotide reductase small subunit; RR2; RR2M
Orthologs: Mus musculus : Rrm2 (ribonucleotide reductase M2)  MGI
Rattus norvegicus : Rrm2 (ribonucleotide reductase M2)
Related Pseudogenes: RRM2P2   RRM2P3   RRM2P4  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1210,233,878 - 10,242,711+NCBI
Human Genome Assembly HuRef210,113,982 - 10,122,746+NCBI
Human Genome Assembly GRCh37210,262,695 - 10,271,546+NCBI
Human Genome Assembly Build 36210,180,184 - 10,188,074+NCBI
Human Cytogenetic Map2p25-p24 NCBI
Human Genome Assembly210,213,332 - 10,221,220 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on RRM2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736125
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-02-27
Status: ACTIVE