| 17alpha-ethynylestradiol | affects expression | ISO | RGD:1598310 | 6480464 | Ethinyl Estradiol affects the expression of RRM2 mRNA | CTD | PMID:17351261 |
| 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of RRM2 mRNA | CTD | PMID:16474171 more ... |
| 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of RRM2 mRNA | CTD | PMID:16474171 PMID:19167446 |
| 17beta-estradiol | affects expression | ISO | RGD:11248 | 6480464 | Estradiol affects the expression of RRM2 mRNA | CTD | PMID:15598610 |
| 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of RRM2 mRNA | CTD | PMID:17404688 |
| 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of RRM2 mRNA | CTD | PMID:16474171 |
| 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of RRM2 mRNA | CTD | PMID:20106945 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RRM2 mRNA | CTD | PMID:20106945 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of RRM2 mRNA | CTD | PMID:22574217 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:11248 | 6480464 | Tetrachlorodibenzodioxin affects the expression of RRM2 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RRM2 mRNA | CTD | PMID:21802500 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:11248 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RRM2 mRNA | CTD | PMID:19465110 PMID:15667827 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:11248 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RRM2 mRNA | CTD | PMID:19770486 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:11248 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RRM2 mRNA | CTD | PMID:15667827 PMID:19465110 |
| 2-butoxyethanol | increases expression | ISO | RGD:11248 | 6480464 | n-butoxyethanol results in increased expression of RRM2 mRNA | CTD | PMID:19812364 |
| 3-methylcholanthrene | increases expression | ISO | RGD:11248 | 6480464 | Methylcholanthrene results in increased expression of RRM2 mRNA | CTD | PMID:20713471 |
| 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:11248 | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of RRM2 mRNA | CTD | PMID:18648102 |
| 4-nitroquinoline N-oxide | decreases expression | ISO | RGD:11248 | 6480464 | 4-Nitroquinoline-1-oxide results in decreased expression of RRM2 mRNA | CTD | PMID:22561872 |
| 5-azacytidine | multiple interactions | EXP | | 6480464 | [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA | CTD | PMID:18720364 |
| 5-fluorouracil | affects expression | EXP | | 6480464 | Fluorouracil affects the expression of RRM2 mRNA | CTD | PMID:15205334 PMID:16584549 |
| 5-fluorouracil | decreases expression | EXP | | 6480464 | Fluorouracil results in decreased expression of RRM2 mRNA | CTD | PMID:17039268 PMID:16557594 |
| 5-fluorouracil | affects expression | EXP | | 6480464 | Fluorouracil affects the expression of RRM2 mRNA | CTD | PMID:16584549 PMID:15205334 |
| 5-fluorouracil | affects response to substance | EXP | | 6480464 | RRM2 protein affects the susceptibility to Fluorouracil | CTD | PMID:15548681 |
| 5-fluorouracil | multiple interactions | EXP | | 6480464 | RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] | CTD | PMID:16896004 |
| 5-fluorouracil | increases expression | EXP | | 6480464 | Fluorouracil results in increased expression of RRM2 mRNA | CTD | PMID:16709241 |
| 5-fluorouracil | decreases expression | EXP | | 6480464 | Fluorouracil results in decreased expression of RRM2 mRNA | CTD | PMID:16557594 PMID:17039268 |
| 8-bromo-3',5'-cyclic AMP | decreases expression | EXP | | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RRM2 mRNA | CTD | PMID:22079614 |
| aflatoxin B1 | affects expression | EXP | | 6480464 | Aflatoxin B1 affects the expression of RRM2 protein | CTD | PMID:20106945 |
| aflatoxin B1 | decreases expression | ISO | RGD:11248 | 6480464 | Aflatoxin B1 results in decreased expression of RRM2 mRNA | CTD | PMID:19770486 |
| all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of RRM2 mRNA | CTD | PMID:15498508 |
| antimycin A | decreases expression | ISO | RGD:11248 | 6480464 | Antimycin A results in decreased expression of RRM2 mRNA | CTD | PMID:19304788 |
| benzo[a]pyrene | decreases expression | ISO | RGD:11248 | 6480464 | Benzo(a)pyrene results in decreased expression of RRM2 mRNA | CTD | PMID:19770486 PMID:17942131 |
| benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of RRM2 mRNA | CTD | PMID:20064835 more ... |
| benzo[a]pyrene | decreases expression | ISO | RGD:11248 | 6480464 | Benzo(a)pyrene results in decreased expression of RRM2 mRNA | CTD | PMID:17942131 PMID:19770486 |
| benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of RRM2 mRNA | CTD | PMID:20106945 PMID:20064835 |
| benzo[a]pyrene | decreases expression | ISO | RGD:11248 | 6480464 | Benzo(a)pyrene results in decreased expression of RRM2 mRNA | CTD | PMID:17942131 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:11248 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of RRM2 mRNA | CTD | PMID:21715664 |
| benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of RRM2 mRNA | CTD | PMID:20064835 PMID:20106945 |
| bicalutamide | decreases expression | EXP | | 6480464 | bicalutamide results in decreased expression of RRM2 mRNA | CTD | PMID:15638997 |
| bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RRM2 mRNA | CTD | PMID:16474171 |
| calcitriol | decreases expression | EXP | | 6480464 | Calcitriol results in decreased expression of RRM2 mRNA | CTD | PMID:21592394 |
| calcitriol | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of RRM2 mRNA | CTD | PMID:21592394 |
| cefaloridine | decreases expression | ISO | RGD:1598310 | 6480464 | Cephaloridine results in decreased expression of RRM2 mRNA | CTD | PMID:18500788 |
| celastrol | decreases expression | EXP | | 6480464 | tripterine results in decreased expression of RRM2 mRNA | CTD | PMID:17010675 |
| ciclopirox | decreases activity | ISO | RGD:11248 | 6480464 | ciclopirox results in decreased activity of RRM2 protein | CTD | PMID:19589922 |
| ciguatoxin CTX1B | affects expression | ISO | RGD:11248 | 6480464 | Ciguatoxins affects the expression of RRM2 mRNA | CTD | PMID:18353800 |
| cisplatin | multiple interactions | EXP | | 6480464 | BRCA1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased activity of and results in increased phosphorylation of CHEK1 protein]]]; more ... | CTD | PMID:21875941 |
| cisplatin | decreases expression | ISO | RGD:1598310 | 6480464 | Cisplatin results in decreased expression of RRM2 mRNA | CTD | PMID:22023808 |
| cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of RRM2 mRNA | CTD | PMID:19320972 PMID:19376846 |
| copper atom | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RRM2 mRNA | CTD | PMID:20971185 |
| copper atom | increases expression | ISO | RGD:1598310 | 6480464 | Copper results in increased expression of RRM2 mRNA | CTD | PMID:22465980 |
| copper(0) | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RRM2 mRNA | CTD | PMID:20971185 |
| copper(0) | increases expression | ISO | RGD:1598310 | 6480464 | Copper results in increased expression of RRM2 mRNA | CTD | PMID:22465980 |
| coumestrol | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of RRM2 mRNA; more ... | CTD | PMID:19167446 |
| coumestrol | increases expression | EXP | | 6480464 | Coumestrol results in increased expression of RRM2 mRNA | CTD | PMID:19167446 |
| cyclophosphamide | multiple interactions | EXP | | 6480464 | RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] | CTD | PMID:16896004 |
| cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of RRM2 mRNA | CTD | PMID:20106945 |
| cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of RRM2 mRNA | CTD | PMID:19159671 more ... |
| cyclosporin A | decreases expression | ISO | RGD:11248 | 6480464 | Cyclosporine results in decreased expression of RRM2 mRNA | CTD | PMID:19770486 PMID:17942131 |
| cyclosporin A | decreases expression | ISO | RGD:11248 | 6480464 | Cyclosporine results in decreased expression of RRM2 mRNA | CTD | PMID:17942131 PMID:19770486 |
| cyclosporin A | decreases expression | ISO | RGD:11248 | 6480464 | Cyclosporine results in decreased expression of RRM2 mRNA | CTD | PMID:17942131 |
| cytarabine | increases expression | EXP | | 6480464 | Cytarabine results in increased expression of RRM2 mRNA | CTD | PMID:19194470 |
| dasatinib (anhydrous) | decreases expression | EXP | | 6480464 | dasatinib results in decreased expression of RRM2 mRNA | CTD | PMID:20579391 |
| Delta(9)-tetrahydrocannabinol | decreases expression | EXP | | 6480464 | Tetrahydrocannabinol results in decreased expression of RRM2 mRNA | CTD | PMID:18454173 |
| dibutyl phthalate | decreases expression | ISO | RGD:11248 | 6480464 | Dibutyl Phthalate results in decreased expression of RRM2 mRNA | CTD | PMID:21266533 |
| dibutyl phthalate | decreases expression | ISO | RGD:1598310 | 6480464 | Dibutyl Phthalate results in decreased expression of RRM2 mRNA | CTD | PMID:21266533 |
| diethyl maleate | increases expression | ISO | RGD:1598310 | 6480464 | diethyl maleate results in increased expression of RRM2 mRNA | CTD | PMID:21161181 |
| dioxygen | multiple interactions | ISO | RGD:11248 | 6480464 | [Iron co-treated with Oxygen] binds to RRM2 protein | CTD | PMID:16829694 |
| doxorubicin | affects expression | EXP | | 6480464 | Doxorubicin affects the expression of RRM2 mRNA | CTD | PMID:15205334 |
| doxorubicin | multiple interactions | EXP | | 6480464 | RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] | CTD | PMID:16896004 |
| gedunin | decreases expression | EXP | | 6480464 | gedunin results in decreased expression of RRM2 mRNA | CTD | PMID:17010675 |
| genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of RRM2 mRNA | CTD | PMID:16474171 |
| genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of RRM2 mRNA | CTD | PMID:16474171 PMID:20884965 |
| indole-3-methanol | multiple interactions | ISO | RGD:1598310 | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RRM2 mRNA | CTD | PMID:22129741 |
| iron atom | multiple interactions | ISO | RGD:11248 | 6480464 | [Iron co-treated with Oxygen] binds to RRM2 protein | CTD | PMID:16829694 |
| ketamine | decreases expression | ISO | RGD:1598310 | 6480464 | Ketamine results in decreased expression of RRM2 mRNA | CTD | PMID:20080153 |
| lucanthone | decreases expression | EXP | | 6480464 | Lucanthone results in decreased expression of RRM2 mRNA | CTD | PMID:21148553 |
| lycopene | increases expression | EXP | | 6480464 | lycopene results in increased expression of RRM2 mRNA | CTD | PMID:16886892 |
| methotrexate | affects expression | ISO | RGD:11248 | 6480464 | Methotrexate affects the expression of RRM2 mRNA | CTD | PMID:18502557 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:11248 | 6480464 | Diethylnitrosamine results in increased expression of RRM2 mRNA | CTD | PMID:17854601 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:1598310 | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RRM2 mRNA | CTD | PMID:22129741 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:1598310 | 6480464 | Diethylnitrosamine results in increased expression of RRM2 mRNA | CTD | PMID:19638242 |
| ozone | increases expression | ISO | RGD:11248 | 6480464 | Ozone results in increased expression of RRM2 mRNA | CTD | PMID:19555225 |
| paclitaxel | multiple interactions | EXP | | 6480464 | RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] | CTD | PMID:16896004 |
| paracetamol | decreases expression | ISO | RGD:11248 | 6480464 | Acetaminophen results in decreased expression of RRM2 mRNA | CTD | PMID:17942131 |
| phenobarbital | multiple interactions | ISO | RGD:11248 | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of RRM2 mRNA] | CTD | PMID:19482888 |
| phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of RRM2 mRNA | CTD | PMID:19159669 |
| phenobarbital | increases expression | ISO | RGD:11248 | 6480464 | Phenobarbital results in increased expression of RRM2 mRNA | CTD | PMID:20403969 PMID:19482888 |
| phenobarbital | increases expression | ISO | RGD:11248 | 6480464 | Phenobarbital results in increased expression of RRM2 mRNA | CTD | PMID:19482888 PMID:20403969 |
| piperonyl butoxide | increases expression | ISO | RGD:1598310 | 6480464 | Piperonyl Butoxide results in increased expression of RRM2 mRNA | CTD | PMID:22484513 |
| pirinixic acid | increases expression | ISO | RGD:11248 | 6480464 | pirinixic acid results in increased expression of RRM2 mRNA | CTD | PMID:18445702 PMID:18301758 |
| pirinixic acid | increases expression | ISO | RGD:11248 | 6480464 | pirinixic acid results in increased expression of RRM2 mRNA | CTD | PMID:18301758 PMID:18445702 |
| piroxicam | decreases expression | EXP | | 6480464 | Piroxicam results in decreased expression of RRM2 mRNA | CTD | PMID:21858171 |
| progesterone | multiple interactions | EXP | | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of RRM2 mRNA | CTD | PMID:17404688 |
| progesterone | increases expression | EXP | | 6480464 | Progesterone results in increased expression of RRM2 mRNA | CTD | PMID:18070364 |
| propiconazole | increases expression | ISO | RGD:11248 | 6480464 | propiconazole results in increased expression of RRM2 mRNA | CTD | PMID:21278054 |
| quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of RRM2 mRNA | CTD | PMID:21632981 |
| resveratrol | decreases expression | EXP | | 6480464 | resveratrol results in decreased expression of RRM2 mRNA | CTD | PMID:15767336 |
| resveratrol | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of RRM2 mRNA | CTD | PMID:19167446 |
| rotenone | decreases expression | ISO | RGD:11248 | 6480464 | Rotenone results in decreased expression of RRM2 mRNA | CTD | PMID:19304788 |
| rotenone | increases expression | ISO | RGD:1598310 | 6480464 | Rotenone results in increased expression of RRM2 mRNA | CTD | PMID:19013527 |
| sodium dichromate | affects expression | ISO | RGD:1598310 | 6480464 | sodium bichromate affects the expression of RRM2 mRNA | CTD | PMID:22110744 |
| sodium dichromate | increases expression | ISO | RGD:11248 | 6480464 | sodium bichromate results in increased expression of RRM2 mRNA | CTD | PMID:22155349 |
| tamibarotene | affects expression | EXP | | 6480464 | Am 80 affects the expression of RRM2 mRNA; more ... | CTD | PMID:15498508 |
| testosterone | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of RRM2 mRNA | CTD | PMID:21592394 |
| testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of RRM2 mRNA | CTD | PMID:21592394 |
| tetrachloromethane | affects expression | ISO | RGD:11248 | 6480464 | Carbon Tetrachloride affects the expression of RRM2 mRNA | CTD | PMID:17484886 |
| thalidomide | multiple interactions | EXP | | 6480464 | [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA | CTD | PMID:18720364 |
| tocopherol | increases expression | ISO | RGD:11248 | 6480464 | Tocopherols results in increased expression of RRM2 mRNA | CTD | PMID:17056531 |
| trans-resveratrol | decreases expression | EXP | | 6480464 | resveratrol results in decreased expression of RRM2 mRNA | CTD | PMID:15767336 |
| trans-resveratrol | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of RRM2 mRNA | CTD | PMID:19167446 |
| trimellitic anhydride | increases expression | ISO | RGD:11248 | 6480464 | trimellitic anhydride results in increased expression of RRM2 mRNA | CTD | PMID:19042947 |
| troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of RRM2 mRNA | CTD | PMID:19140230 |
| valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of RRM2 mRNA | CTD | PMID:19101580 |
| valproic acid | decreases expression | ISO | RGD:11248 | 6480464 | Valproic Acid results in decreased expression of RRM2 mRNA | CTD | PMID:21427059 |
| vincaleukoblastine | affects response to substance | EXP | | 6480464 | RRM2 protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 |