MAPT (microtubule-associated protein tau)

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Keyword

Gene: MAPT (microtubule-associated protein tau) Homo sapiens

Symbol:

MAPT

Name:

microtubule-associated protein tau

Description:

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPTL; MGC138549; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; MSTD; MTBT1; MTBT2; neurofibrillary tangle protein; OTTHUMP00000239567; OTTHUMP00000239568; OTTHUMP00000239569; OTTHUMP00000239570; OTTHUMP00000239571; paired helical filament-tau; PHF-tau; PPND; TAU

Orthologs:

Mus musculus : Mapt (microtubule-associated protein tau) MGI
Rattus norvegicus : Mapt (microtubule-associated protein tau)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	17	45,168,771 - 45,302,704	+	NCBI
Human Genome Assembly HuRef	17	39,635,406 - 39,768,427	+	NCBI
Human Genome Assembly GRCh37	17	43,971,748 - 44,105,700	+	NCBI
Human Genome Assembly Build 36	17	41,327,624 - 41,461,547	+	NCBI
Human Cytogenetic Map	17	q21.1		NCBI
Human Genome Assembly	17	41,327,623 - 41,458,611		NCBI