Gene: TSC2 (tuberous sclerosis 2)  Homo sapiens
Symbol: TSC2
Name: tuberous sclerosis 2
Description: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ43106; LAM; OTTHUMP00000158940; OTTHUMP00000198394; OTTHUMP00000198395; TSC4; tuberin; tuberous sclerosis 2 protein
Orthologs: Mus musculus : Tsc2 (tuberous sclerosis 2)  MGI
Rattus norvegicus : Tsc2 (tuberous sclerosis 2)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1162,032,784 - 2,073,362+NCBI
Human Genome Assembly HuRef162,022,255 - 2,063,441+NCBI
Human Genome Assembly GRCh37162,097,990 - 2,138,713+NCBI
Human Genome Assembly Build 36162,037,991 - 2,078,714+NCBI
Human Cytogenetic Map16p13.3 NCBI
Human Genome Assembly162,038,599 - 2,078,713 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

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Disease Annotations
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References - curated
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RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
  
More on TSC2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736193
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-04-16
Status: ACTIVE



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