Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lithium chloride
go back to main search page
Accession:CHEBI:48607 term browser browse the term
Definition:A metal chloride salt with a Li(+) counterion.
Synonyms:related_synonym: Formula=ClLi;   InChI=1S/ClH.Li/h1H;/q;+1/p-1;   InChIKey=KWGKDLIKAYFUFQ-UHFFFAOYSA-M;   LiCl;   Lithiumchlorid;   SMILES=[Li+].[Cl-];   chlorure de lithium;   cloruro de litio;   lithii chloridum
 xref: CAS:7447-41-8
 xref_mesh: MESH:D018021
 xref: PMID:21301855;   PMID:24398558



show annotations for term's descendants           Sort by:
lithium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase decreases expression EXP Lithium Chloride results in decreased expression of ABAT mRNA CTD PMID:15711924 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 increases expression EXP Lithium Chloride results in increased expression of ABCB1 protein CTD PMID:18624906 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABHD11 abhydrolase domain containing 11 increases expression EXP Lithium Chloride results in increased expression of ABHD11 mRNA CTD PMID:23527032 NCBI chr 7:73,736,094...73,738,802
Ensembl chr 7:73,736,094...73,738,852
JBrowse link
G ABI2 abl interactor 2 decreases expression EXP Lithium Chloride results in decreased expression of ABI2 mRNA CTD PMID:23527032 NCBI chr 2:203,328,394...203,432,169
Ensembl chr 2:203,328,280...203,447,728
JBrowse link
G AC024940.1 ovostatin 2 decreases expression EXP Lithium Chloride results in decreased expression of OVOS2 mRNA CTD PMID:23527032 NCBI chr12:31,111,652...31,201,235
Ensembl chr12:31,111,652...31,201,235
JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain decreases expression ISO Lithium Chloride results in decreased expression of ACADM mRNA; Lithium Chloride results in decreased expression of ACADM protein CTD PMID:26993217 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
JBrowse link
G ACE angiotensin I converting enzyme multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE protein] CTD PMID:32494933 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACHE acetylcholinesterase (Yt blood group) multiple interactions
increases degradation
decreases stability
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in decreased stability of ACHE protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein CTD PMID:22944069 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ADGRB3 adhesion G protein-coupled receptor B3 increases expression EXP Lithium Chloride results in increased expression of ADGRB3 mRNA CTD PMID:15711924 NCBI chr 6:68,635,282...69,389,506
Ensembl chr 6:68,635,282...69,390,571
JBrowse link
G ADGRE5 adhesion G protein-coupled receptor E5 increases expression EXP Lithium Chloride results in increased expression of ADGRE5 mRNA CTD PMID:23527032 NCBI chr19:14,381,444...14,408,723
Ensembl chr19:14,380,501...14,408,725
JBrowse link
G AFG3L1P AFG3 like matrix AAA peptidase subunit 1, pseudogene decreases expression EXP Lithium Chloride results in decreased expression of AFG3L1 mRNA CTD PMID:23527032 NCBI chr16:89,972,580...90,000,787
Ensembl chr16:89,972,581...90,002,161
Ensembl chr16:89,972,581...90,002,161
JBrowse link
G AGTR1 angiotensin II receptor type 1 multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of AGTR1A protein] CTD PMID:32494933 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AGTR2 angiotensin II receptor type 2 multiple interactions ISO [Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of AGTR2 mRNA CTD PMID:32494933 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA CTD PMID:21498875 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein]
[Lithium Chloride co-treated with Pilocarpine] results in increased phosphorylation of AKT1 protein
CTD PMID:22820424 PMID:31018114 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 decreases expression EXP Lithium Chloride results in decreased expression of ALDH1A3 mRNA CTD PMID:15711924 NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,877,714...100,916,626
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein increases expression EXP Lithium Chloride results in increased expression of ALOX5AP mRNA CTD PMID:23527032 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426
JBrowse link
G ALPG alkaline phosphatase, germ cell increases expression EXP Lithium Chloride results in increased expression of ALPG mRNA CTD PMID:23527032 NCBI chr 2:232,406,844...232,410,714
Ensembl chr 2:232,406,844...232,410,714
JBrowse link
G ALPP alkaline phosphatase, placental increases activity EXP Lithium Chloride results in increased activity of ALPP protein CTD PMID:16053526 NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889
JBrowse link
G ANXA11 annexin A11 increases expression EXP Lithium Chloride results in increased expression of ANXA11 mRNA CTD PMID:23527032 NCBI chr10:80,150,889...80,205,808
Ensembl chr10:80,150,889...80,205,572
JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 decreases expression EXP Lithium Chloride results in decreased expression of APC2 mRNA CTD PMID:23527032 NCBI chr19:1,446,230...1,473,244
Ensembl chr19:1,446,302...1,473,244
JBrowse link
G APEH acylaminoacyl-peptide hydrolase increases expression EXP Lithium Chloride results in increased expression of APEH mRNA CTD PMID:23527032 NCBI chr 3:49,673,117...49,683,971
Ensembl chr 3:49,674,014...49,683,971
JBrowse link
G APP amyloid beta precursor protein multiple interactions EXP Lithium Chloride inhibits the reaction [Copper affects the localization of APP protein] CTD PMID:24610780 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G AQP2 aquaporin 2 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of AQP2 mRNA; Lithium Chloride results in decreased expression of AQP2 protein
PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]
CTD PMID:18653713 PMID:19692487 PMID:21734099 NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
JBrowse link
G ARF6 ADP ribosylation factor 6 increases expression EXP Lithium Chloride results in increased expression of ARF6 mRNA CTD PMID:15711924 NCBI chr14:49,893,082...49,897,054
Ensembl chr14:49,893,079...49,897,054
JBrowse link
G ARHGAP29 Rho GTPase activating protein 29 increases expression EXP Lithium Chloride results in increased expression of ARHGAP29 mRNA CTD PMID:15711924 NCBI chr 1:94,168,905...94,314,592
Ensembl chr 1:94,148,988...94,275,068
JBrowse link
G ASB1 ankyrin repeat and SOCS box containing 1 decreases expression EXP Lithium Chloride results in decreased expression of ASB1 mRNA CTD PMID:23527032 NCBI chr 2:238,426,927...238,452,250
Ensembl chr 2:238,426,742...238,452,250
JBrowse link
G ATF4 activating transcription factor 4 increases expression EXP Lithium Chloride results in increased expression of ATF4 mRNA CTD PMID:15711924 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
JBrowse link
G ATP5ME ATP synthase membrane subunit e decreases expression EXP Lithium Chloride results in decreased expression of ATP5ME mRNA CTD PMID:15711924 NCBI chr 4:672,436...674,276
Ensembl chr 4:672,436...674,330
JBrowse link
G AVP arginine vasopressin increases expression ISO Lithium Chloride results in increased expression of AVP mRNA; Lithium Chloride results in increased expression of AVP protein CTD PMID:9406968 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
JBrowse link
G AXIN2 axin 2 multiple interactions
increases expression
ISO
EXP
[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; Phenobarbital inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
CTD PMID:20694829 PMID:21498875 PMID:22493441 PMID:23326414 PMID:24534281 More... NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648
JBrowse link
G B4GALT1 beta-1,4-galactosyltransferase 1 increases expression EXP Lithium Chloride results in increased expression of B4GALT1 mRNA CTD PMID:23527032 NCBI chr 9:33,104,077...33,185,089
Ensembl chr 9:33,104,082...33,167,356
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
Lithium Chloride inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Lithium Chloride inhibits the reaction [Paraquat results in increased expression of BAX protein]
Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in increased expression of BAX protein]]; Lithium Chloride inhibits the reaction [Matrines results in increased expression of BAX protein]
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX protein]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX protein
CTD PMID:26074776 PMID:30171970 PMID:31220555 PMID:34813134 PMID:37075934 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of BCL2 mRNA; Lithium Chloride results in increased expression of BCL2 protein
[Lithium Chloride results in increased abundance of Lithium] promotes the reaction [Paraquat results in increased expression of BCL2 mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 protein; [Paraquat co-treated with [Lithium Chloride results in increased abundance of Lithium]] results in increased expression of BCL2 protein
Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
Lithium Chloride inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]
CTD PMID:17404573 PMID:18830594 PMID:19101580 PMID:19408126 PMID:26074776 More... NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 increases expression EXP Lithium Chloride results in increased expression of BCL2L1 mRNA; Lithium Chloride results in increased expression of BCL2L1 protein CTD PMID:19101580 PMID:22493441 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL3 BCL3 transcription coactivator increases expression EXP Lithium Chloride results in increased expression of BCL3 mRNA CTD PMID:23527032 NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions EXP [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased expression of BDNF mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased secretion of BDNF protein]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BDNF mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased secretion of BDNF protein CTD PMID:26074776 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein affects expression
multiple interactions
EXP Lithium Chloride affects the expression of BGLAP mRNA
Lithium Chloride affects the reaction [perfluorooctane sulfonic acid affects the expression of BGLAP mRNA]
CTD PMID:30738844 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions
increases expression
ISO
EXP
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA]
Lithium Chloride results in increased expression of BIRC5 protein
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of BIRC5 protein]
CTD PMID:24464479 PMID:28886972 PMID:35985571 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BMP4 bone morphogenetic protein 4 increases expression EXP Lithium Chloride results in increased expression of BMP4 mRNA CTD PMID:15711924 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BST2 bone marrow stromal cell antigen 2 increases expression EXP Lithium Chloride results in increased expression of BST2 mRNA CTD PMID:23527032 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630
JBrowse link
G CALR calreticulin decreases expression ISO Lithium Chloride results in decreased expression of CALR mRNA CTD PMID:26993217 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CASP3 caspase 3 multiple interactions
decreases activity
EXP
ISO
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [fipronil results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]]; Lithium Chloride inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
Lithium Chloride results in decreased activity of CASP3 protein
CTD PMID:19101580 PMID:21296133 PMID:21364661 PMID:24464479 PMID:26074776 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP4 caspase 4 increases expression EXP Lithium Chloride results in increased expression of CASP4 mRNA CTD PMID:23527032 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366
JBrowse link
G CASP5 caspase 5 increases expression EXP Lithium Chloride results in increased expression of CASP5 mRNA CTD PMID:23527032 NCBI chr11:104,994,243...105,023,168
Ensembl chr11:104,994,235...105,023,168
JBrowse link
G CASP7 caspase 7 multiple interactions EXP Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form] CTD PMID:28886972 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP9 caspase 9 multiple interactions EXP Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein] CTD PMID:28343033 PMID:28886972 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression ISO Lithium Chloride results in increased expression of CCL2 mRNA CTD PMID:33901603 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCNA1 cyclin A1 increases expression
decreases expression
EXP Lithium Chloride results in increased expression of CCNA1 protein
Lithium Chloride results in decreased expression of CCNA1 mRNA
CTD PMID:19101580 PMID:23527032 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870
JBrowse link
G CCNA2 cyclin A2 decreases expression
multiple interactions
EXP
ISO
Lithium Chloride results in decreased expression of CCNA2 mRNA; Lithium Chloride results in decreased expression of CCNA2 protein
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]]
CTD PMID:15845746 PMID:17440966 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCNB2 cyclin B2 decreases expression EXP Lithium Chloride results in decreased expression of CCNB2 mRNA CTD PMID:15711924 PMID:17440966 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
JBrowse link
G CCND1 cyclin D1 affects localization
affects expression
decreases expression
increases expression
multiple interactions
decreases phosphorylation
EXP
ISO
Lithium Chloride affects the localization of CCND1 protein
Lithium Chloride affects the expression of CCND1 protein
Lithium Chloride results in decreased expression of CCND1 protein
Lithium Chloride results in increased expression of CCND1 mRNA; Lithium Chloride results in increased expression of CCND1 protein
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol affects the localization of CCND1 protein]]
Lithium Chloride results in decreased phosphorylation of CCND1 protein
[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [baicalein results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in increased phosphorylation of CCND1 protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of CCND1 mRNA]
CTD PMID:15753396 PMID:15845746 PMID:16024653 PMID:16076840 PMID:17440966 More... NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND2 cyclin D2 increases expression ISO Lithium Chloride results in increased expression of CCND2 mRNA CTD PMID:27226553 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
JBrowse link
G CCND3 cyclin D3 increases expression ISO Lithium Chloride results in increased expression of CCND3 mRNA CTD PMID:27226553 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
JBrowse link
G CCNE2 cyclin E2 decreases expression
increases expression
EXP Lithium Chloride results in decreased expression of CCNE2 mRNA; Lithium Chloride results in decreased expression of CCNE2 protein
Lithium Chloride results in increased expression of CCNE2 mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678
JBrowse link
G CCNG2 cyclin G2 decreases expression
increases expression
EXP Lithium Chloride results in decreased expression of CCNG2 mRNA
Lithium Chloride results in increased expression of CCNG2 mRNA
CTD PMID:15711924 PMID:17440966 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388
JBrowse link
G CD40 CD40 molecule increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of CD40 protein
rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of CD40 protein]
CTD PMID:18455351 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD44 CD44 molecule (IN blood group) increases expression EXP Lithium Chloride results in increased expression of CD44 mRNA CTD PMID:23527032 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CDC25C cell division cycle 25C decreases expression
increases expression
EXP Lithium Chloride results in decreased expression of CDC25C mRNA; Lithium Chloride results in decreased expression of CDC25C protein
Lithium Chloride results in increased expression of CDC25C mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
JBrowse link
G CDC42EP2 CDC42 effector protein 2 decreases expression EXP Lithium Chloride results in decreased expression of CDC42EP2 mRNA CTD PMID:23527032 NCBI chr11:65,314,866...65,322,417
Ensembl chr11:65,314,866...65,322,417
JBrowse link
G CDC42SE1 CDC42 small effector 1 increases expression EXP Lithium Chloride results in increased expression of CDC42SE1 mRNA CTD PMID:23527032 NCBI chr 1:151,050,985...151,059,622
Ensembl chr 1:151,050,971...151,070,325
JBrowse link
G CDC6 cell division cycle 6 decreases expression
increases expression
EXP Lithium Chloride results in decreased expression of CDC6 mRNA; Lithium Chloride results in decreased expression of CDC6 protein
Lithium Chloride results in increased expression of CDC6 mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657
JBrowse link
G CDC7 cell division cycle 7 decreases expression EXP Lithium Chloride results in decreased expression of CDC7 mRNA CTD PMID:23527032 NCBI chr 1:91,500,851...91,525,764
Ensembl chr 1:91,500,851...91,525,764
JBrowse link
G CDH1 cadherin 1 multiple interactions
decreases expression
EXP [Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in increased expression of CDH1 protein]; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in increased expression of CDH1 protein]
Lithium Chloride results in decreased expression of CDH1 protein
CTD PMID:20348013 PMID:22134133 PMID:32112862 PMID:35985571 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDH11 cadherin 11 multiple interactions EXP [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein] CTD PMID:19274078 NCBI chr16:64,943,753...65,123,744
Ensembl chr16:64,943,753...65,126,112
JBrowse link
G CDH2 cadherin 2 decreases expression
multiple interactions
increases expression
EXP Lithium Chloride results in decreased expression of CDH2 mRNA
Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of CDH2 protein]
Lithium Chloride results in increased expression of CDH2 protein
CTD PMID:23527032 PMID:32112862 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP Lithium Chloride results in increased expression of CDKN1A mRNA; Lithium Chloride results in increased expression of CDKN1A protein CTD PMID:17440966 PMID:34624459 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases expression EXP Lithium Chloride results in decreased expression of CDKN1B mRNA CTD PMID:17440966 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C increases expression EXP Lithium Chloride results in increased expression of CDKN1C mRNA CTD PMID:17440966 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A increases expression EXP Lithium Chloride results in increased expression of CDKN2A mRNA CTD PMID:23527032 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B increases expression EXP Lithium Chloride results in increased expression of CDKN2B mRNA CTD PMID:23527032 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of CEBPA mRNA] CTD PMID:32494933 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CEBPD CCAAT enhancer binding protein delta increases expression EXP Lithium Chloride results in increased expression of CEBPD mRNA CTD PMID:23527032 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164
JBrowse link
G CELF2 CUGBP Elav-like family member 2 decreases expression EXP Lithium Chloride results in decreased expression of CELF2 mRNA CTD PMID:23527032 NCBI chr10:10,462,550...11,336,675
Ensembl chr10:10,798,397...11,336,675
JBrowse link
G CENPF centromere protein F decreases expression EXP Lithium Chloride results in decreased expression of CENPF mRNA CTD PMID:15711924 PMID:23527032 NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574
JBrowse link
G CEP250 centrosomal protein 250 decreases expression EXP Lithium Chloride results in decreased expression of CEP250 mRNA CTD PMID:23527032 NCBI chr20:35,455,165...35,519,280
Ensembl chr20:35,455,164...35,519,280
JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist increases expression ISO Lithium Chloride results in increased expression of CER1 mRNA CTD PMID:26272751 NCBI chr 9:14,717,326...14,722,733
Ensembl chr 9:14,719,724...14,722,733
JBrowse link
G CFD complement factor D increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of CFD mRNA
Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of CFD mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of CFD mRNA]
CTD PMID:23527032 PMID:28291828 NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884
JBrowse link
G CFTR CF transmembrane conductance regulator increases expression EXP Lithium Chloride results in increased expression of CFTR mRNA CTD PMID:23527032 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CHGA chromogranin A decreases expression ISO Lithium Chloride results in decreased expression of CHGA mRNA; Lithium Chloride results in decreased expression of CHGA protein CTD PMID:33901603 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285
JBrowse link
G CHGB chromogranin B decreases expression ISO Lithium Chloride results in decreased expression of CHGB mRNA CTD PMID:33901603 NCBI chr20:5,911,510...5,925,353
Ensembl chr20:5,911,510...5,925,353
JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 increases expression EXP Lithium Chloride results in increased expression of CHORDC1 mRNA CTD PMID:15711924 NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077
JBrowse link
G CKM creatine kinase, M-type increases expression ISO Lithium Chloride results in increased expression of CKM mRNA CTD PMID:20694829 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875
JBrowse link
G CLDN1 claudin 1 increases expression ISO Lithium Chloride results in increased expression of CLDN1 mRNA CTD PMID:33901603 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
JBrowse link
G CLDN12 claudin 12 decreases expression ISO Lithium Chloride results in decreased expression of CLDN12 mRNA CTD PMID:33901603 NCBI chr 7:90,403,461...90,415,954
Ensembl chr 7:90,383,721...90,513,402
JBrowse link
G CLDN15 claudin 15 decreases expression ISO Lithium Chloride results in decreased expression of CLDN15 mRNA; Lithium Chloride results in decreased expression of CLDN15 protein CTD PMID:33901603 NCBI chr 7:101,232,094...101,238,820
Ensembl chr 7:101,232,092...101,238,820
JBrowse link
G CLK2 CDC like kinase 2 decreases expression EXP Lithium Chloride results in decreased expression of CLK2 mRNA CTD PMID:15711924 NCBI chr 1:155,262,868...155,273,504
Ensembl chr 1:155,262,868...155,278,491
JBrowse link
G COL13A1 collagen type XIII alpha 1 chain decreases expression EXP Lithium Chloride results in decreased expression of COL13A1 mRNA CTD PMID:23527032 NCBI chr10:69,801,906...69,959,144
Ensembl chr10:69,801,880...69,964,275
JBrowse link
G COL1A2 collagen type I alpha 2 chain affects expression ISO Lithium Chloride affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases expression
increases phosphorylation
ISO
EXP
Lithium Chloride results in increased expression of CREB1 mRNA
Lithium Chloride results in increased phosphorylation of CREB1 protein
CTD PMID:18830594 PMID:19285016 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRISP2 cysteine rich secretory protein 2 decreases expression EXP Lithium Chloride results in decreased expression of CRISP2 mRNA CTD PMID:15711924 NCBI chr 6:49,676,652...49,714,220
Ensembl chr 6:49,692,358...49,713,590
JBrowse link
G CTAGE4 CTAGE family member 4 increases expression EXP Lithium Chloride results in increased expression of CTAGE4 mRNA CTD PMID:23527032 NCBI chr 7:144,183,466...144,186,080
Ensembl chr 7:144,183,466...144,186,080
JBrowse link
G CTCF CCCTC-binding factor increases expression ISO Lithium Chloride results in increased expression of CTCF mRNA CTD PMID:19285016 NCBI chr16:67,562,526...67,639,185
Ensembl chr16:67,562,467...67,639,177
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions
increases expression
affects localization
increases stability
increases activity
increases localization
decreases phosphorylation
EXP
ISO
[Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; Hexachlorophene inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Aspirin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [celastrol results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Indomethacin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of and results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of and results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Lithium Chloride results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased localization of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased localization of and results in increased activity of CTNNB1 protein; MALAT1 protein affects the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]
Lithium Chloride affects the localization of CTNNB1 protein; Lithium Chloride affects the localization of CTNNB1 protein modified form
Lithium Chloride results in increased stability of CTNNB1 protein
Lithium Chloride results in increased expression of CTNNB1 mRNA; Lithium Chloride results in increased expression of CTNNB1 protein
Lithium Chloride results in increased activity of CTNNB1 protein
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein]
Lithium Chloride results in increased localization of CTNNB1 protein
[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride results in increased expression of and affects the localization of CTNNB1 protein
Lithium Chloride results in decreased phosphorylation of CTNNB1 protein
CTD PMID:12813129 PMID:15364539 PMID:16053526 PMID:16076840 PMID:16735606 More... NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Lithium Chloride inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]; Lithium Chloride inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]; Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]]; Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] CTD PMID:33396024 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression ISO Lithium Chloride results in increased expression of CYP1A1 mRNA CTD PMID:21498875 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions ISO Lithium Chloride promotes the reaction [Cadmium results in increased expression of DDIT3 protein] CTD PMID:27658547 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DIRAS3 DIRAS family GTPase 3 increases expression EXP Lithium Chloride results in increased expression of DIRAS3 mRNA CTD PMID:15711924 NCBI chr 1:68,045,962...68,050,627
Ensembl chr 1:68,045,886...68,051,717
JBrowse link
G DVL2 dishevelled segment polarity protein 2 multiple interactions ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of DVL2 protein] CTD PMID:30171970 NCBI chr17:7,225,342...7,234,517
Ensembl chr17:7,225,342...7,234,517
JBrowse link
G EBF1 EBF transcription factor 1 increases expression ISO Lithium Chloride results in increased expression of EBF1 mRNA CTD PMID:27226553 NCBI chr 5:158,695,920...159,099,916
Ensembl chr 5:158,695,920...159,099,916
JBrowse link
G EFNA3 ephrin A3 decreases expression ISO Lithium Chloride results in decreased expression of EFNA3 mRNA CTD PMID:18772502 NCBI chr 1:155,078,837...155,087,538
Ensembl chr 1:155,078,837...155,087,538
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions
increases expression
EXP [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA]
Lithium Chloride results in increased expression of EGFR mRNA; Lithium Chloride results in increased expression of EGFR protein
CTD PMID:22493441 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ENOX2 ecto-NOX disulfide-thiol exchanger 2 decreases expression EXP Lithium Chloride results in decreased expression of ENOX2 mRNA CTD PMID:23527032 NCBI chr  X:130,622,325...130,903,209
Ensembl chr  X:130,622,325...130,903,234
JBrowse link
G EPHA5 EPH receptor A5 decreases expression ISO Lithium Chloride results in decreased expression of EPHA5 mRNA; Lithium Chloride results in decreased expression of EPHA5 protein CTD PMID:18772502 NCBI chr 4:65,319,567...65,670,489
Ensembl chr 4:65,319,563...65,670,495
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]]; Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] CTD PMID:33396024 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 increases expression EXP Lithium Chloride results in increased expression of ERBB3 mRNA CTD PMID:23527032 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression EXP Lithium Chloride results in increased expression of ERCC1 mRNA CTD PMID:15711924 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP [Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; Lithium Chloride inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]; Lithium Chloride inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein]; Lithium Chloride results in decreased phosphorylation of and results in decreased stability of and results in decreased expression of ESR1 protein CTD PMID:16076840 PMID:26990689 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESRRG estrogen related receptor gamma increases expression EXP Lithium Chloride results in increased expression of ESRRG mRNA CTD PMID:23527032 NCBI chr 1:216,503,246...217,137,702
Ensembl chr 1:216,503,246...217,137,755
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases expression
EXP Lithium Chloride inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]
Lithium Chloride results in decreased expression of F3 mRNA
CTD PMID:15371228 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V increases expression EXP Lithium Chloride results in increased expression of F5 mRNA CTD PMID:23527032 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G FAM90A1 family with sequence similarity 90 member A1 decreases expression EXP Lithium Chloride results in decreased expression of FAM90A1 mRNA CTD PMID:23527032 NCBI chr12:8,221,260...8,227,618
Ensembl chr12:8,221,260...8,227,618
JBrowse link
G FBXO32 F-box protein 32 decreases expression ISO Lithium Chloride results in decreased expression of FBXO32 mRNA CTD PMID:21832246 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 multiple interactions EXP FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein] CTD PMID:25897075 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FGF21 fibroblast growth factor 21 increases expression ISO Lithium increases expression of Fgf21 mRNA in cerebellar granular cells and hippocampal and cortical neurons RGD PMID:24468826 RGD:10401923 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
JBrowse link
G FMN2 formin 2 decreases expression EXP Lithium Chloride results in decreased expression of FMN2 mRNA CTD PMID:23527032 NCBI chr 1:240,091,883...240,475,187
Ensembl chr 1:240,014,348...240,475,187
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Butyrates promotes the reaction [Lithium Chloride results in increased expression of FOS protein] CTD PMID:20346924 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FXYD5 FXYD domain containing ion transport regulator 5 increases expression EXP Lithium Chloride results in increased expression of FXYD5 mRNA CTD PMID:23527032 NCBI chr19:35,154,735...35,169,881
Ensembl chr19:35,154,730...35,169,881
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in decreased phosphorylation of FYN protein]; Lithium Chloride inhibits the reaction [triptolide results in increased expression of FYN protein] CTD PMID:30926361 PMID:32763437 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G FZD3 frizzled class receptor 3 increases expression EXP Lithium Chloride results in increased expression of FZD3 mRNA CTD PMID:20069066 NCBI chr 8:28,494,212...28,574,258
Ensembl chr 8:28,494,205...28,574,267
JBrowse link
G FZD4 frizzled class receptor 4 increases expression EXP Lithium Chloride results in increased expression of FZD4 mRNA CTD PMID:20069066 NCBI chr11:86,945,679...86,955,395
Ensembl chr11:86,945,679...86,955,395
JBrowse link
G FZD6 frizzled class receptor 6 increases expression EXP Lithium Chloride results in increased expression of FZD6 mRNA CTD PMID:20069066 NCBI chr 8:103,298,494...103,332,866
Ensembl chr 8:103,298,433...103,332,866
JBrowse link
G GATA1 GATA binding protein 1 multiple interactions ISO GATA1 protein results in decreased susceptibility to [Lithium Chloride co-treated with Tretinoin] CTD PMID:19230972 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,540...48,794,311
JBrowse link
G GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) increases expression EXP Lithium Chloride results in increased expression of GBGT1 mRNA CTD PMID:23527032 NCBI chr 9:133,152,948...133,163,914
Ensembl chr 9:133,152,948...133,163,933
JBrowse link
G GCG glucagon multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter]
Lithium Chloride results in increased expression of GCG mRNA
CTD PMID:19582394 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
JBrowse link
G GDA guanine deaminase increases expression EXP Lithium Chloride results in increased expression of GDA mRNA CTD PMID:23527032 NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193
JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions EXP
ISO
Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP protein; Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]
CTD PMID:23872260 PMID:31018114 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GIP gastric inhibitory polypeptide multiple interactions
increases expression
ISO [[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter]
Lithium Chloride results in increased expression of GIP mRNA
CTD PMID:19582394 NCBI chr17:48,958,554...48,968,596
Ensembl chr17:48,958,554...48,968,596
JBrowse link
G GJA1 gap junction protein alpha 1 affects localization
increases expression
multiple interactions
ISO Lithium Chloride affects the localization of GJA1 protein
Lithium Chloride results in increased expression of GJA1 protein
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein
CTD PMID:18972237 PMID:21177194 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GLB1 galactosidase beta 1 increases activity EXP Lithium Chloride results in increased activity of GLB1 protein CTD PMID:34624459 NCBI chr 3:32,961,108...33,097,146
Ensembl chr 3:32,996,609...33,097,202
JBrowse link
G GLUD1 glutamate dehydrogenase 1 multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in decreased expression of GLUD1 mRNA] CTD PMID:32494933 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
JBrowse link
G GNAZ G protein subunit alpha z decreases expression EXP Lithium Chloride results in decreased expression of GNAZ mRNA CTD PMID:23527032 NCBI chr22:23,070,519...23,125,032
Ensembl chr22:23,070,519...23,125,032
JBrowse link
G GNPAT glyceronephosphate O-acyltransferase decreases expression EXP Lithium Chloride results in decreased expression of GNPAT mRNA CTD PMID:23527032 NCBI chr 1:231,241,212...231,277,973
Ensembl chr 1:231,241,207...231,277,973
JBrowse link
G GRAMD2A GRAM domain containing 2A increases expression EXP Lithium Chloride results in increased expression of GRAMD2A mRNA CTD PMID:23527032 NCBI chr15:72,159,806...72,197,787
Ensembl chr15:72,159,806...72,197,787
JBrowse link
G GRAMD2B GRAM domain containing 2B increases expression EXP Lithium Chloride results in increased expression of GRAMD2B mRNA CTD PMID:23527032 NCBI chr 5:126,360,120...126,494,364
Ensembl chr 5:126,360,132...126,496,494
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
decreases expression
ISO
EXP
[[Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA] which affects the susceptibility to Excitatory Amino Acid Agonists; [Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA
Lithium Chloride results in decreased expression of GRIN1 mRNA
CTD PMID:19285052 PMID:34748853 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
JBrowse link
G GRM1 glutamate metabotropic receptor 1 multiple interactions ISO [Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of GRM1 mRNA CTD PMID:32494933 NCBI chr 6:146,027,707...146,437,601
Ensembl chr 6:146,027,646...146,437,601
JBrowse link
G GRN granulin precursor increases expression EXP Lithium Chloride results in increased expression of GRN mRNA CTD PMID:23527032 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha multiple interactions ISO Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3A protein] CTD PMID:27658547 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625
JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
increases expression
decreases activity
decreases expression
increases stability
affects phosphorylation
decreases phosphorylation
EXP
ISO
[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in decreased expression of GSK3B protein modified form]; Lithium Chloride inhibits the reaction [celastrol results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [quinocetone affects the phosphorylation of and results in decreased activity of GSK3B protein]; Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in decreased expression of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of and results in decreased activity of GSK3B protein; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein; PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein]
Lithium Chloride results in increased phosphorylation of GSK3B protein
[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cisplatin results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein
Lithium Chloride results in increased expression of GSK3B protein modified form
Lithium Chloride results in decreased expression of GSK3B mRNA
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride co-treated with Cisplatin] results in increased phosphorylation of GSK3B protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; calyculin A promotes the reaction [Lithium Chloride results in increased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Lithium Chloride inhibits the reaction [Matrines results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Sevoflurane results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein
Lithium Chloride results in increased stability of GSK3B protein
Lithium Chloride affects the phosphorylation of GSK3B protein
Lithium Chloride results in decreased phosphorylation of GSK3B protein
CTD PMID:12813129 PMID:15247282 PMID:15364539 PMID:15585669 PMID:15753396 More... NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSTM3 glutathione S-transferase mu 3 multiple interactions ISO [Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA CTD PMID:20118494 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
JBrowse link
G H1-2 H1.2 linker histone, cluster member decreases expression EXP Lithium Chloride results in decreased expression of H1-2 mRNA CTD PMID:15711924 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,055,740...26,056,470
JBrowse link
G H2AC17 H2A clustered histone 17 decreases expression EXP Lithium Chloride results in decreased expression of H2AC17 mRNA CTD PMID:15711924 NCBI chr 6:27,892,699...27,893,185
Ensembl chr 6:27,892,699...27,893,185
JBrowse link
G H2BC13 H2B clustered histone 13 decreases expression EXP Lithium Chloride results in decreased expression of H2BC13 mRNA CTD PMID:15711924 NCBI chr 6:27,807,479...27,807,929
Ensembl chr 6:27,807,479...27,807,929
JBrowse link
G H4C4 H4 clustered histone 4 decreases expression EXP Lithium Chloride results in decreased expression of H4C4 mRNA CTD PMID:15711924 NCBI chr 6:26,188,710...26,189,112
Ensembl chr 6:26,188,710...26,189,112
JBrowse link
G HAPLN1 hyaluronan and proteoglycan link protein 1 increases expression EXP Lithium Chloride results in increased expression of HAPLN1 mRNA CTD PMID:23527032 NCBI chr 5:83,637,805...83,720,855
Ensembl chr 5:83,637,805...83,720,855
JBrowse link
G HDAC1 histone deacetylase 1 multiple interactions ISO Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HDAC7 histone deacetylase 7 decreases expression ISO Lithium Chloride results in decreased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr12:47,782,722...47,821,344
Ensembl chr12:47,782,722...47,833,132
JBrowse link
G HDGFL3 HDGF like 3 decreases expression EXP Lithium Chloride results in decreased expression of HDGFL3 mRNA CTD PMID:15711924 NCBI chr15:83,112,738...83,207,823
Ensembl chr15:83,112,738...83,207,875
JBrowse link
G HES7 hes family bHLH transcription factor 7 increases expression ISO Lithium Chloride results in increased expression of HES7 mRNA CTD PMID:23326414 NCBI chr17:8,120,592...8,126,634
Ensembl chr17:8,120,592...8,124,106
JBrowse link
G HMGB1 high mobility group box 1 multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 protein] CTD PMID:32494933 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of HMOX1 mRNA
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of HMOX1 mRNA; Lithium Chloride promotes the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein]
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of HMOX1 protein]; Lithium Chloride promotes the reaction [Cadmium results in increased expression of HMOX1 protein]
CTD PMID:23527032 PMID:26074776 PMID:27658547 PMID:30672058 PMID:33645131 More... NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HSPA12A heat shock protein family A (Hsp70) member 12A decreases expression EXP Lithium Chloride results in decreased expression of HSPA12A mRNA CTD PMID:23527032 NCBI chr10:116,671,192...116,850,747
Ensembl chr10:116,671,192...116,850,251
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions EXP [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form CTD PMID:20090934 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A decreases expression EXP Lithium Chloride results in decreased expression of HTR2A mRNA CTD PMID:23527032 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
JBrowse link
G IBSP integrin binding sialoprotein decreases expression ISO Lithium Chloride results in decreased expression of IBSP mRNA CTD PMID:19442631 NCBI chr 4:87,799,554...87,812,435
Ensembl chr 4:87,799,554...87,812,435
JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Lithium Chloride results in increased expression of ICAM1 mRNA CTD PMID:23527032 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G ID3 inhibitor of DNA binding 3 decreases expression EXP Lithium Chloride results in decreased expression of ID3 mRNA CTD PMID:15711924 NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein] CTD PMID:31760073 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDS iduronate 2-sulfatase increases expression EXP Lithium Chloride results in increased expression of IDS mRNA CTD PMID:23527032 NCBI chr  X:149,476,988...149,505,306
Ensembl chr  X:149,476,988...149,521,096
JBrowse link
G IFNG interferon gamma increases expression ISO Lithium Chloride results in increased expression of IFNG mRNA CTD PMID:9328138 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions ISO Lithium Chloride promotes the reaction [IGF1 protein results in increased expression of MYH4 mRNA] CTD PMID:19657059 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) decreases expression ISO Lithium Chloride results in decreased expression of IGHA mRNA CTD PMID:33901603 NCBI chr14:105,586,937...105,588,394
Ensembl chr14:105,583,731...105,588,395
JBrowse link
G IGLL1 immunoglobulin lambda like polypeptide 1 increases expression ISO Lithium Chloride results in increased expression of IGLL1 mRNA CTD PMID:27226553 NCBI chr22:23,573,125...23,580,290
Ensembl chr22:23,573,125...23,580,302
JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of IL1B protein
Lithium Chloride results in increased expression of IL1B mRNA
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B protein
CTD PMID:19010416 PMID:31018114 PMID:33901603 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 increases expression ISO Lithium Chloride results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of IL6 mRNA
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 protein; Lithium Chloride inhibits the reaction [Valproic Acid results in increased expression of IL6 protein]
CTD PMID:9328138 PMID:31018114 PMID:36535311 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains increases expression EXP Lithium Chloride results in increased expression of ILRUN mRNA CTD PMID:23527032 NCBI chr 6:34,587,288...34,696,767
Ensembl chr 6:34,587,288...34,696,859
JBrowse link
G IQCA1 IQ motif containing with AAA domain 1 increases expression EXP Lithium Chloride results in increased expression of IQCA1 mRNA CTD PMID:23527032 NCBI chr 2:236,306,685...236,507,476
Ensembl chr 2:236,324,147...236,507,535
JBrowse link
G ITGAM integrin subunit alpha M multiple interactions EXP Lithium Chloride promotes the reaction [Tretinoin results in increased expression of ITGAM protein] CTD PMID:29743969 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITGB8 integrin subunit beta 8 increases expression EXP Lithium Chloride results in increased expression of ITGB8 mRNA CTD PMID:15711924 NCBI chr 7:20,329,766...20,415,754
Ensembl chr 7:20,330,702...20,415,754
JBrowse link
G JDP2 Jun dimerization protein 2 increases expression EXP Lithium Chloride results in increased expression of JDP2 mRNA CTD PMID:23527032 NCBI chr14:75,426,943...75,474,107
Ensembl chr14:75,427,716...75,474,111
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Lithium Chloride results in decreased expression of JUN mRNA CTD PMID:26272751 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KBTBD11 kelch repeat and BTB domain containing 11 decreases expression EXP Lithium Chloride results in decreased expression of KBTBD11 mRNA CTD PMID:23527032 NCBI chr 8:1,973,677...2,006,936
Ensembl chr 8:1,973,677...2,006,936
JBrowse link
G KCNK6 potassium two pore domain channel subfamily K member 6 increases expression EXP Lithium Chloride results in increased expression of KCNK6 mRNA CTD PMID:23527032 NCBI chr19:38,319,845...38,332,076
Ensembl chr19:38,319,845...38,332,076
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 increases expression EXP Lithium Chloride results in increased expression of KCNN4 mRNA CTD PMID:23527032 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976
JBrowse link
G KDR kinase insert domain receptor increases expression ISO Lithium Chloride results in increased expression of KDR mRNA CTD PMID:26272751 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KIF5A kinesin family member 5A decreases expression EXP Lithium Chloride results in decreased expression of KIF5A mRNA CTD PMID:23527032 NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633
JBrowse link
G KRT19 keratin 19 increases expression EXP Lithium Chloride results in increased expression of KRT19 mRNA CTD PMID:23527032 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308
JBrowse link
G KRT34 keratin 34 increases expression EXP Lithium Chloride results in increased expression of KRT34 mRNA CTD PMID:15711924 NCBI chr17:41,377,669...41,383,816
Ensembl chr17:41,377,669...41,382,306
JBrowse link
G LAMC1 laminin subunit gamma 1 increases expression EXP Lithium Chloride results in increased expression of LAMC1 mRNA CTD PMID:23527032 NCBI chr 1:183,023,420...183,145,592
Ensembl chr 1:183,023,420...183,145,592
JBrowse link
G LCP1 lymphocyte cytosolic protein 1 increases expression EXP Lithium Chloride results in increased expression of LCP1 mRNA CTD PMID:23527032 NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 multiple interactions ISO Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
JBrowse link
G LGR5 leucine rich repeat containing G protein-coupled receptor 5 increases expression ISO Lithium Chloride results in increased expression of LGR5 mRNA CTD PMID:33901603 NCBI chr12:71,439,129...71,586,310
Ensembl chr12:71,439,798...71,586,310
JBrowse link
G LIG4 DNA ligase 4 increases expression ISO Lithium Chloride results in increased expression of LIG4 mRNA; Lithium Chloride results in increased expression of LIG4 protein CTD PMID:19285016 NCBI chr13:108,207,442...108,218,349
Ensembl chr13:108,207,439...108,218,368
JBrowse link
G LRP6 LDL receptor related protein 6 increases expression EXP Lithium Chloride results in increased expression of LRP6 mRNA CTD PMID:20069066 NCBI chr12:12,116,025...12,267,044
Ensembl chr12:12,116,025...12,267,044
JBrowse link
G MAGED2 MAGE family member D2 decreases expression EXP Lithium Chloride results in decreased expression of MAGED2 mRNA CTD PMID:23527032 NCBI chr  X:54,807,745...54,816,015
Ensembl chr  X:54,807,599...54,816,015
JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 multiple interactions EXP MALAT1 protein affects the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MMP7 protein]; MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MYC protein]; MALAT1 protein affects the reaction [resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]]; MALAT1 protein affects the reaction [resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein]]; MALAT1 protein affects the reaction [resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]] CTD PMID:24244343 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 affects phosphorylation ISO Lithium Chloride affects the phosphorylation of MAPK1 protein CTD PMID:21364661 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK10 mitogen-activated protein kinase 10 decreases expression EXP Lithium Chloride results in decreased expression of MAPK10 mRNA CTD PMID:23527032 NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 affects phosphorylation ISO Lithium Chloride affects the phosphorylation of MAPK3 protein CTD PMID:21364661 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPT microtubule associated protein tau multiple interactions
decreases expression
ISO
EXP
[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; Lithium Chloride inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPT protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]]; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]
Lithium Chloride results in decreased expression of MAPT mRNA
CTD PMID:20937724 PMID:23527032 PMID:27050422 PMID:35993674 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
JBrowse link
G MARVELD2 MARVEL domain containing 2 increases expression EXP Lithium Chloride results in increased expression of MARVELD2 mRNA CTD PMID:23527032 NCBI chr 5:69,415,116...69,444,330
Ensembl chr 5:69,415,065...69,444,330
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member increases expression EXP Lithium Chloride results in increased expression of MCL1 mRNA; Lithium Chloride results in increased expression of MCL1 protein CTD PMID:22493441 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
JBrowse link
G MCM2 minichromosome maintenance complex component 2 decreases expression EXP Lithium Chloride results in decreased expression of MCM2 mRNA CTD PMID:17440966 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,223...127,622,436
JBrowse link
G MCM4 minichromosome maintenance complex component 4 decreases expression EXP Lithium Chloride results in decreased expression of MCM4 mRNA CTD PMID:17440966 NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160
JBrowse link
G MCM5 minichromosome maintenance complex component 5 decreases expression EXP Lithium Chloride results in decreased expression of MCM5 mRNA CTD PMID:17440966 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431
JBrowse link
G MCM6 minichromosome maintenance complex component 6 decreases expression EXP Lithium Chloride results in decreased expression of MCM6 mRNA CTD PMID:17440966 NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443
JBrowse link
G MCM7 minichromosome maintenance complex component 7 decreases expression EXP Lithium Chloride results in decreased expression of MCM7 mRNA CTD PMID:17440966 NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 increases expression ISO Lithium Chloride results in increased expression of MESP1 mRNA CTD PMID:26272751 NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249
JBrowse link
G MEX3B mex-3 RNA binding family member B decreases expression EXP Lithium Chloride results in decreased expression of MEX3B mRNA CTD PMID:23527032 NCBI chr15:82,041,778...82,046,018
Ensembl chr15:82,041,778...82,046,119
JBrowse link
G MIB1 MIB E3 ubiquitin protein ligase 1 decreases expression EXP Lithium Chloride results in decreased expression of MIB1 mRNA CTD PMID:23527032 NCBI chr18:21,704,916...21,870,953
Ensembl chr18:21,704,957...21,870,953
JBrowse link
G MIR152 microRNA 152 increases expression ISO Lithium Chloride results in increased expression of MIR152 mRNA CTD PMID:19254429 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247
JBrowse link
G MIR155 microRNA 155 increases expression ISO Lithium Chloride results in increased expression of MIR155 mRNA CTD PMID:19254429 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR200C microRNA 200c multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] results in increased expression of MIR200C mRNA CTD PMID:31018114 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766
JBrowse link
G MIR221 microRNA 221 increases expression ISO Lithium Chloride results in increased expression of MIR221 mRNA CTD PMID:19254429 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266
JBrowse link
G MIR34A microRNA 34a multiple interactions EXP [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of MIR34A mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of MIR34A mRNA CTD PMID:26074776 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777
JBrowse link
G MIR494 microRNA 494 decreases expression ISO Lithium Chloride results in decreased expression of MIR494 mRNA CTD PMID:19254429 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714
JBrowse link
G MITF melanocyte inducing transcription factor increases expression EXP Lithium Chloride results in increased expression of MITF mRNA CTD PMID:23527032 NCBI chr 3:69,739,464...69,968,332
Ensembl chr 3:69,739,456...69,968,336
JBrowse link
G MIXL1 Mix paired-like homeobox increases expression ISO Lithium Chloride results in increased expression of MIXL1 mRNA CTD PMID:26272751 NCBI chr 1:226,223,664...226,227,060
Ensembl chr 1:226,223,618...226,227,060
JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of MKI67 protein]] CTD PMID:15845746 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor decreases expression EXP Lithium Chloride results in decreased expression of MLLT11 mRNA CTD PMID:23527032 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
JBrowse link
G MMAB metabolism of cobalamin associated B decreases expression EXP Lithium Chloride results in decreased expression of MMAB mRNA CTD PMID:23527032 NCBI chr12:109,553,715...109,573,504
Ensembl chr12:109,553,715...109,573,580
JBrowse link
G MMP7 matrix metallopeptidase 7 multiple interactions
increases expression
EXP MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MMP7 protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein]]; Resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein] CTD PMID:24244343 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MPZ myelin protein zero increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of MPZ mRNA; Lithium Chloride results in increased expression of MPZ protein
Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ protein]
CTD PMID:27788593 NCBI chr 1:161,303,600...161,309,968
Ensembl chr 1:161,304,735...161,309,968
JBrowse link
G MRPL47 mitochondrial ribosomal protein L47 decreases expression EXP Lithium Chloride results in decreased expression of MRPL47 mRNA CTD PMID:15711924 NCBI chr 3:179,588,285...179,604,646
Ensembl chr 3:179,588,285...179,604,649
JBrowse link
G MSGN1 mesogenin 1 increases expression ISO Lithium Chloride results in increased expression of MSGN1 mRNA CTD PMID:23326414 NCBI chr 2:17,816,460...17,817,798
Ensembl chr 2:17,816,460...17,817,798
JBrowse link
G MSI1 musashi RNA binding protein 1 increases expression EXP Lithium Chloride results in increased expression of MSI1 protein CTD PMID:20069066 NCBI chr12:120,339,662...120,369,164
Ensembl chr12:120,341,330...120,369,164
JBrowse link
G MT1G metallothionein 1G increases expression EXP Lithium Chloride results in increased expression of MT1G mRNA CTD PMID:23527032 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions
decreases expression
ISO
EXP
Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein]
Lithium Chloride results in decreased expression of MTOR mRNA
CTD PMID:30171970 PMID:34748853 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions
affects expression
increases expression
ISO
EXP
Lithium Chloride inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYC protein]
Lithium Chloride affects the expression of MYC protein
Lithium Chloride results in increased expression of MYC mRNA; Lithium Chloride results in increased expression of MYC protein
Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of MYC protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of MYC protein]; MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MYC protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]]
CTD PMID:19679347 PMID:22100782 PMID:22493441 PMID:24244343 PMID:26272751 More... NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYCT1 MYC target 1 increases expression EXP Lithium Chloride results in increased expression of MYCT1 mRNA CTD PMID:23527032 NCBI chr 6:152,697,897...152,747,181
Ensembl chr 6:152,697,897...152,724,569
JBrowse link
G MYH4 myosin heavy chain 4 multiple interactions
increases expression
ISO Lithium Chloride promotes the reaction [IGF1 protein results in increased expression of MYH4 mRNA]
Lithium Chloride results in increased expression of MYH4 mRNA
CTD PMID:19657059 PMID:20694829 NCBI chr17:10,443,263...10,469,559
Ensembl chr17:10,443,290...10,469,559
JBrowse link
G MYH8 myosin heavy chain 8 increases expression ISO Lithium Chloride results in increased expression of MYH8 mRNA CTD PMID:20694829 NCBI chr17:10,390,322...10,421,950
Ensembl chr17:10,390,322...10,421,950
JBrowse link
G MYO1E myosin IE increases expression ISO Lithium Chloride results in increased expression of MYO1E mRNA CTD PMID:26272751 NCBI chr15:59,132,434...59,372,871
Ensembl chr15:59,132,434...59,372,871
JBrowse link
G NANOG Nanog homeobox increases expression
multiple interactions
EXP Lithium Chloride results in increased expression of NANOG mRNA
Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of NANOG protein]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA]
CTD PMID:20069066 PMID:37551626 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146
JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase increases expression ISO Lithium Chloride results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
JBrowse link
G NES nestin increases expression ISO Lithium Chloride results in increased expression of NES mRNA CTD PMID:26272751 NCBI chr 1:156,668,763...156,677,407
Ensembl chr 1:156,668,763...156,677,407
JBrowse link
G NEUROD1 neuronal differentiation 1 decreases expression ISO Lithium Chloride results in decreased expression of NEUROD1 mRNA CTD PMID:33901603 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 increases activity ISO Lithium Chloride results in increased activity of NFATC3 protein CTD PMID:20694829 NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO
EXP
Lithium Chloride affects the reaction [triptolide affects the expression of NFE2L2 protein]; Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of NFE2L2 protein]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of NFE2L2 protein]
[Lithium Chloride results in increased abundance of Lithium] which affects the localization of NFE2L2 protein; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NFE2L2 mRNA
CTD PMID:26074776 PMID:30926361 PMID:32763437 PMID:37075934 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKBIA NFKB inhibitor alpha increases degradation EXP Lithium Chloride results in increased degradation of NFKBIA protein CTD PMID:24085292 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NHLH1 nescient helix-loop-helix 1 decreases expression EXP Lithium Chloride results in decreased expression of NHLH1 mRNA CTD PMID:23527032 NCBI chr 1:160,367,071...160,372,846
Ensembl chr 1:160,367,071...160,372,846
JBrowse link
G NKD1 NKD inhibitor of WNT signaling pathway 1 increases expression
multiple interactions
EXP Lithium Chloride results in increased expression of NKD1 mRNA
Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]
CTD PMID:24534281 NCBI chr16:50,548,396...50,649,249
Ensembl chr16:50,548,396...50,649,249
JBrowse link
G NOS1 nitric oxide synthase 1 increases expression ISO Lithium Chloride results in increased expression of NOS1 mRNA CTD PMID:9500967 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression EXP Lithium Chloride results in increased expression of NOS2 mRNA CTD PMID:19679347 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOTCH1 notch receptor 1 decreases expression EXP Lithium Chloride results in decreased expression of NOTCH1 mRNA CTD PMID:23527032 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NPEPL1 aminopeptidase like 1 increases expression EXP Lithium Chloride results in increased expression of NPEPL1 mRNA CTD PMID:23527032 NCBI chr20:58,689,131...58,715,844
Ensembl chr20:58,689,131...58,719,238
JBrowse link
G NPPB natriuretic peptide B multiple interactions ISO Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]] CTD PMID:34813134 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP
ISO
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NQO1 mRNA
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of NQO1 protein]]
CTD PMID:26074776 PMID:33645131 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 protein] CTD PMID:32494933 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 multiple interactions
increases expression
ISO CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of NR4A2 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein]
Lithium Chloride results in increased expression of NR4A2 mRNA; Lithium Chloride results in increased expression of NR4A2 protein
CTD PMID:27045591 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348
JBrowse link
G NRCAM neuronal cell adhesion molecule decreases expression ISO Lithium Chloride results in decreased expression of NRCAM mRNA CTD PMID:26272751 NCBI chr 7:108,147,649...108,456,720
Ensembl chr 7:108,147,623...108,456,717
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 decreases expression EXP Lithium Chloride results in decreased expression of NSD2 mRNA CTD PMID:23527032 NCBI chr 4:1,871,393...1,982,192
Ensembl chr 4:1,871,393...1,982,207
JBrowse link
G NTN1 netrin 1 decreases expression EXP Lithium Chloride results in decreased expression of NTN1 mRNA CTD PMID:23527032 NCBI chr17:9,003,087...9,244,000
Ensembl chr17:9,021,510...9,244,000
JBrowse link
G OCLN occludin decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of OCLN mRNA
Lithium Chloride results in increased expression of OCLN protein
CTD PMID:33901603 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G OPRM1 opioid receptor mu 1 decreases expression ISO Lithium Chloride results in decreased expression of OPRM1 protein CTD PMID:17919468 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO
EXP
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; [Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]; Lithium Chloride promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]
Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]
CTD PMID:27658547 PMID:28343033 PMID:28886972 PMID:30377735 PMID:31396050 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PAX3 paired box 3 increases expression EXP Lithium Chloride results in increased expression of PAX3 protein CTD PMID:19101580 NCBI chr 2:222,199,887...222,298,998
Ensembl chr 2:222,199,887...222,298,998
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of PCK1 mRNA
Lithium Chloride inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]; Lithium Chloride inhibits the reaction [Dexamethasone results in increased expression of PCK1 mRNA]
CTD PMID:1371108 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of PCNA protein]]
Lithium Chloride results in increased expression of PCNA protein
CTD PMID:15845746 PMID:27018151 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PDE4B phosphodiesterase 4B decreases expression EXP Lithium Chloride results in decreased expression of PDE4B mRNA CTD PMID:23527032 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579
JBrowse link
G PDGFRL platelet derived growth factor receptor like increases expression EXP Lithium Chloride results in increased expression of PDGFRL mRNA CTD PMID:23527032 NCBI chr 8:17,576,433...17,643,144
Ensembl chr 8:17,576,433...17,644,071
JBrowse link
G PDIA5 protein disulfide isomerase family A member 5 increases expression EXP Lithium Chloride results in increased expression of PDIA5 mRNA CTD PMID:23527032 NCBI chr 3:123,067,025...123,162,104
Ensembl chr 3:123,067,025...123,225,227
JBrowse link
G PDLIM5 PDZ and LIM domain 5 increases expression EXP Lithium Chloride results in increased expression of PDLIM5 mRNA CTD PMID:15711924 NCBI chr 4:94,451,942...94,668,223
Ensembl chr 4:94,451,857...94,668,227
JBrowse link
G PDXK pyridoxal kinase increases expression EXP Lithium Chloride results in increased expression of PDXK mRNA CTD PMID:23527032 NCBI chr21:43,719,129...43,762,299
Ensembl chr21:43,719,094...43,762,307
JBrowse link
G PEA15 proliferation and apoptosis adaptor protein 15 multiple interactions ISO [Pilocarpine co-treated with Lithium Chloride co-treated with 3-chloroacetylindole] results in decreased phosphorylation of PEA15 protein; [Pilocarpine co-treated with Lithium Chloride] results in decreased phosphorylation of PEA15 protein CTD PMID:31396050 NCBI chr 1:160,205,384...160,215,372
Ensembl chr 1:160,205,380...160,215,376
JBrowse link
G PIGR polymeric immunoglobulin receptor decreases expression ISO Lithium Chloride results in decreased expression of PIGR mRNA CTD PMID:33901603 NCBI chr 1:206,928,522...206,946,466
Ensembl chr 1:206,928,522...206,946,466
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions
increases response to substance
affects response to substance
EXP PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein]
PIK3CA protein mutant form results in increased susceptibility to Lithium Chloride
PIK3CA protein affects the susceptibility to Lithium Chloride
CTD PMID:19196980 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PITPNB phosphatidylinositol transfer protein beta increases expression EXP Lithium Chloride results in increased expression of PITPNB mRNA CTD PMID:15711924 NCBI chr22:27,851,669...27,919,256
Ensembl chr22:27,851,669...27,920,134
JBrowse link
G PLAGL1 PLAG1 like zinc finger 1 decreases expression EXP Lithium Chloride results in decreased expression of PLAGL1 mRNA CTD PMID:23527032 NCBI chr 6:143,940,300...144,064,599
Ensembl chr 6:143,940,300...144,064,599
JBrowse link
G PLAU plasminogen activator, urokinase decreases expression
increases expression
EXP Lithium Chloride results in decreased expression of PLAU mRNA
Lithium Chloride results in increased expression of PLAU mRNA
CTD PMID:15711924 PMID:23527032 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PLD1 phospholipase D1 increases expression EXP Lithium Chloride results in increased expression of PLD1 mRNA CTD PMID:23527032 NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950
JBrowse link
G PLEKHA6 pleckstrin homology domain containing A6 decreases expression EXP Lithium Chloride results in decreased expression of PLEKHA6 mRNA CTD PMID:23527032 NCBI chr 1:204,218,853...204,378,168
Ensembl chr 1:204,218,853...204,378,214
JBrowse link
G PLIN1 perilipin 1 multiple interactions ISO Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of PLIN1 mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of PLIN1 mRNA] CTD PMID:28291828 NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427
JBrowse link
G PLPP2 phospholipid phosphatase 2 increases expression EXP Lithium Chloride results in increased expression of PLPP2 mRNA CTD PMID:23527032 NCBI chr19:281,043...291,403
Ensembl chr19:281,040...291,403
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP Lithium Chloride results in increased expression of PMAIP1 mRNA; Lithium Chloride results in increased expression of PMAIP1 protein CTD PMID:15711924 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305
JBrowse link
G PMEL premelanosome protein increases expression EXP Lithium Chloride results in increased expression of PMEL mRNA CTD PMID:23527032 NCBI chr12:55,954,105...55,966,709
Ensembl chr12:55,954,105...55,973,317
JBrowse link
G PMP22 peripheral myelin protein 22 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of PMP22 mRNA; Lithium Chloride results in increased expression of PMP22 protein
Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 protein]
CTD PMID:27788593 NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292
JBrowse link
G POLR3B RNA polymerase III subunit B decreases expression EXP Lithium Chloride results in decreased expression of POLR3B mRNA CTD PMID:23527032 NCBI chr12:106,357,748...106,510,198
Ensembl chr12:106,357,748...106,510,198
JBrowse link
G POPDC3 popeye domain containing 3 increases expression EXP Lithium Chloride results in increased expression of POPDC3 mRNA CTD PMID:15711924 NCBI chr 6:105,157,900...105,180,014
Ensembl chr 6:105,157,900...105,180,014
JBrowse link
G POU5F1 POU class 5 homeobox 1 multiple interactions
increases expression
EXP CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of POU5F1 protein]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]
Lithium Chloride results in increased expression of POU5F1 mRNA; Lithium Chloride results in increased expression of POU5F1 protein
CTD PMID:20069066 PMID:20074550 PMID:37551626 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression EXP Lithium Chloride results in increased expression of PPARG mRNA CTD PMID:23527032 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H increases expression EXP Lithium Chloride results in increased expression of PPM1H mRNA CTD PMID:23527032 NCBI chr12:62,643,994...62,935,150
Ensembl chr12:62,643,994...62,935,150
JBrowse link
G PPP1R14C protein phosphatase 1 regulatory inhibitor subunit 14C decreases expression EXP Lithium Chloride results in decreased expression of PPP1R14C mRNA CTD PMID:23527032 NCBI chr 6:150,143,044...150,250,392
Ensembl chr 6:150,143,044...150,250,392
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha increases expression EXP Lithium Chloride results in increased expression of PPP3R1 mRNA CTD PMID:15711924 NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
JBrowse link
G PRR16 proline rich 16 decreases expression EXP Lithium Chloride results in decreased expression of PRR16 mRNA CTD PMID:15711924 NCBI chr 5:120,464,278...120,794,594
Ensembl chr 5:120,464,300...120,687,332
JBrowse link
G PSME1 proteasome activator subunit 1 increases expression EXP Lithium Chloride results in increased expression of PSME1 mRNA CTD PMID:23527032 NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967
JBrowse link
G PTGES prostaglandin E synthase increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of PTGES protein
[Lithium Chloride results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostone; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]
CTD PMID:19692487 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression EXP
ISO
Lithium Chloride results in increased expression of PTGS2 mRNA; Lithium Chloride results in increased expression of PTGS2 protein CTD PMID:9500967 PMID:15585669 PMID:15711924 PMID:19797860 PMID:24085292 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTX3 pentraxin 3 decreases expression EXP Lithium Chloride results in decreased expression of PTX3 mRNA CTD PMID:23527032 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633
JBrowse link
G PURG purine rich element binding protein G decreases expression EXP Lithium Chloride results in decreased expression of PURG mRNA CTD PMID:23527032 NCBI chr 8:30,995,802...31,033,356
Ensembl chr 8:30,995,802...31,033,715
JBrowse link
G PXN paxillin increases expression EXP Lithium Chloride results in increased expression of PXN mRNA CTD PMID:23527032 NCBI chr12:120,210,447...120,265,730
Ensembl chr12:120,210,439...120,265,771
JBrowse link
G PYCARD PYD and CARD domain containing increases expression EXP Lithium Chloride results in increased expression of PYCARD mRNA CTD PMID:23527032 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
JBrowse link
G RAB23 RAB23, member RAS oncogene family increases expression EXP Lithium Chloride results in increased expression of RAB23 mRNA CTD PMID:15711924 NCBI chr 6:57,186,992...57,222,307
Ensembl chr 6:57,186,992...57,222,307
JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions ISO
EXP
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]]
Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein]
CTD PMID:15845746 PMID:22820424 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RBM23 RNA binding motif protein 23 decreases expression EXP Lithium Chloride results in decreased expression of RBM23 mRNA CTD PMID:23527032 NCBI chr14:22,893,204...22,919,149
Ensembl chr14:22,893,204...22,919,182
JBrowse link
G RCAN1 regulator of calcineurin 1 increases expression EXP Lithium Chloride results in increased expression of RCAN1 mRNA CTD PMID:15711924 NCBI chr21:34,516,442...34,615,113
Ensembl chr21:34,513,142...34,615,113
JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK mRNA; [Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK protein CTD PMID:31018114 NCBI chr 9:36,036,913...36,124,455
Ensembl chr 9:36,036,913...36,124,455
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
decreases phosphorylation
increases phosphorylation
ISO
EXP
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; [Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]
Lithium Chloride results in decreased phosphorylation of RELA protein
Lithium Chloride results in increased phosphorylation of RELA protein
CTD PMID:24085292 PMID:31396050 PMID:33901603 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G REXO2 RNA exonuclease 2 increases expression EXP Lithium Chloride results in increased expression of REXO2 mRNA CTD PMID:23527032 NCBI chr11:114,439,467...114,450,279
Ensembl chr11:114,439,435...114,450,279
JBrowse link
G RGS4 regulator of G protein signaling 4 increases expression EXP Lithium Chloride results in increased expression of RGS4 mRNA; Lithium Chloride results in increased expression of RGS4 protein CTD PMID:15711924 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 multiple interactions EXP FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein]; Lithium Chloride results in increased expression of and results in decreased ubiquitination of RICTOR protein CTD PMID:25897075 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402
JBrowse link
G RND3 Rho family GTPase 3 increases expression EXP Lithium Chloride results in increased expression of RND3 mRNA CTD PMID:15711924 NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011
JBrowse link
G RNF144B ring finger protein 144B increases degradation
multiple interactions
EXP Lithium Chloride results in increased degradation of RNF144B protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of RNF144B protein]; Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]
CTD PMID:29724995 NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870
JBrowse link
G RNF40 ring finger protein 40 increases expression ISO Lithium Chloride results in increased expression of RNF40 protein CTD PMID:21734099 NCBI chr16:30,761,612...30,776,307
Ensembl chr16:30,761,745...30,776,307
JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression EXP Lithium Chloride results in increased expression of RRAD mRNA CTD PMID:15711924 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535
JBrowse link
G RTN1 reticulon 1 decreases expression EXP Lithium Chloride results in decreased expression of RTN1 mRNA CTD PMID:23527032 NCBI chr14:59,595,976...59,870,776
Ensembl chr14:59,595,976...59,870,776
JBrowse link
G S100A3 S100 calcium binding protein A3 increases expression EXP Lithium Chloride results in increased expression of S100A3 mRNA CTD PMID:23527032 NCBI chr 1:153,547,329...153,549,258
Ensembl chr 1:153,547,329...153,549,258
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 decreases activity EXP Lithium Chloride results in decreased activity of SCN5A protein CTD PMID:16144991 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,743
JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha increases expression EXP Lithium Chloride results in increased expression of SCNN1A mRNA CTD PMID:23527032 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730
JBrowse link
G SCPEP1 serine carboxypeptidase 1 increases expression EXP Lithium Chloride results in increased expression of SCPEP1 mRNA CTD PMID:23527032 NCBI chr17:56,978,131...57,006,768
Ensembl chr17:56,978,129...57,006,768
JBrowse link
G SFRP2 secreted frizzled related protein 2 decreases expression
multiple interactions
EXP Lithium Chloride results in decreased expression of SFRP2 mRNA
SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]
CTD PMID:20069066 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 decreases expression EXP Lithium Chloride results in decreased expression of SHANK2 mRNA CTD PMID:34748853 NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577
JBrowse link
G SHF Src homology 2 domain containing F decreases expression EXP Lithium Chloride results in decreased expression of SHF mRNA CTD PMID:23527032 NCBI chr15:45,167,214...45,201,116
Ensembl chr15:45,167,214...45,201,175
JBrowse link
G SHH sonic hedgehog signaling molecule decreases expression ISO Lithium Chloride results in decreased expression of SHH mRNA CTD PMID:26272751 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SHPK sedoheptulokinase increases expression EXP Lithium Chloride results in increased expression of SHPK mRNA CTD PMID:23527032 NCBI chr17:3,608,240...3,636,250
Ensembl chr17:3,608,240...3,636,250
JBrowse link
G SIX1 SIX homeobox 1 increases expression
increases response to substance
EXP Lithium Chloride results in increased expression of SIX1 mRNA; Lithium Chloride results in increased expression of SIX1 protein
SIX1 protein results in increased susceptibility to Lithium Chloride
CTD PMID:19101580 NCBI chr14:60,643,421...60,649,477
Ensembl chr14:60,643,421...60,658,259
JBrowse link
G SLC12A1 solute carrier family 12 member 1 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of SLC12A1 protein
PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]
CTD PMID:19692487 NCBI chr15:48,206,302...48,304,078
Ensembl chr15:48,178,438...48,304,078
JBrowse link
G SLC20A1 solute carrier family 20 member 1 increases expression EXP Lithium Chloride results in increased expression of SLC20A1 mRNA CTD PMID:15711924 NCBI chr 2:112,645,939...112,663,825
Ensembl chr 2:112,645,939...112,663,825
JBrowse link
G SLC3A2 solute carrier family 3 member 2 increases expression EXP Lithium Chloride results in increased expression of SLC3A2 mRNA CTD PMID:15711924 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
JBrowse link
G SLC5A3 solute carrier family 5 member 3 increases expression EXP Lithium Chloride results in increased expression of SLC5A3 mRNA CTD PMID:15711924 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260
JBrowse link
G SLC6A4 solute carrier family 6 member 4 decreases expression EXP Lithium Chloride results in decreased expression of SLC6A4 mRNA CTD PMID:34748853 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
JBrowse link
G SLC9A1 solute carrier family 9 member A1 multiple interactions ISO Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in increased expression of NHE1 protein]] CTD PMID:34813134 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
G SNAI1 snail family transcriptional repressor 1 decreases degradation
multiple interactions
EXP
ISO
Lithium Chloride results in decreased degradation of SNAI1 protein
[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein
[Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of SNAI1 protein]
CTD PMID:19440036 PMID:20348013 PMID:35985571 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886
JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions EXP Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of SNAI2 protein] CTD PMID:35985571 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740
JBrowse link
G SNCA synuclein alpha increases expression EXP Lithium Chloride results in increased expression of SNCA mRNA CTD PMID:23527032 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in decreased activity of SOD2 protein] CTD PMID:31760073 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPAG5 sperm associated antigen 5 decreases expression EXP Lithium Chloride results in decreased expression of SPAG5 mRNA CTD PMID:23527032 NCBI chr17:28,577,574...28,599,025
Ensembl chr17:28,577,565...28,599,025
JBrowse link
G SQOR sulfide quinone oxidoreductase increases expression EXP Lithium Chloride results in increased expression of SQOR mRNA CTD PMID:23527032 NCBI chr15:45,631,148...45,691,281
Ensembl chr15:45,631,148...45,691,281
JBrowse link
G SQSTM1 sequestosome 1 multiple interactions ISO Lithium Chloride promotes the reaction [Cisplatin results in decreased expression of SQSTM1 protein] CTD PMID:31220555 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G STARD7 StAR related lipid transfer domain containing 7 multiple interactions EXP [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein CTD PMID:19679347 NCBI chr 2:96,184,859...96,208,827
Ensembl chr 2:96,184,859...96,208,827
JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions EXP Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G STAT6 signal transducer and activator of transcription 6 increases expression EXP Lithium Chloride results in increased expression of STAT6 mRNA CTD PMID:23527032 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
JBrowse link
G SUMF1 sulfatase modifying factor 1 increases expression EXP Lithium Chloride results in increased expression of SUMF1 mRNA CTD PMID:23527032 NCBI chr 3:4,034,486...4,467,269
Ensembl chr 3:3,700,814...4,467,273
JBrowse link
G TARS1 threonyl-tRNA synthetase 1 increases expression EXP Lithium Chloride results in increased expression of TARS1 mRNA CTD PMID:15711924 NCBI chr 5:33,440,696...33,468,091
Ensembl chr 5:33,440,696...33,468,091
JBrowse link
G TBC1D8 TBC1 domain family member 8 decreases expression EXP Lithium Chloride results in decreased expression of TBC1D8 mRNA CTD PMID:15711924 NCBI chr 2:101,007,228...101,151,382
Ensembl chr 2:101,007,228...101,252,866
JBrowse link
G TCF4 transcription factor 4 multiple interactions EXP Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]] CTD PMID:22935447 NCBI chr18:55,222,185...55,635,957
Ensembl chr18:55,222,185...55,664,787
JBrowse link
G TCF7L2 transcription factor 7 like 2 multiple interactions ISO Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678
JBrowse link
G TERF2IP TERF2 interacting protein decreases expression EXP Lithium Chloride results in decreased expression of TERF2IP mRNA CTD PMID:23527032 NCBI chr16:75,647,773...75,657,432
Ensembl chr16:75,647,773...75,761,872
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 increases expression EXP Lithium Chloride results in increased expression of TGFBR2 mRNA CTD PMID:23527032 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249
JBrowse link
G TJP1 tight junction protein 1 decreases expression ISO Lithium Chloride results in decreased expression of TJP1 mRNA CTD PMID:33901603 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of TLR4 mRNA] CTD PMID:32494933 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TM4SF1 transmembrane 4 L six family member 1 increases expression EXP Lithium Chloride results in increased expression of TM4SF1 mRNA CTD PMID:15711924 NCBI chr 3:149,369,022...149,377,649
Ensembl chr 3:149,369,022...149,377,692
JBrowse link
G TMPRSS2 transmembrane serine protease 2 increases expression EXP Lithium Chloride results in increased expression of TMPRSS2 mRNA CTD PMID:23527032 NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116
JBrowse link
G TNC tenascin C increases expression EXP Lithium Chloride results in increased expression of TNC mRNA CTD PMID:15711924 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of TNF protein
Lithium Chloride results in increased expression of TNF mRNA
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF protein; Rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of TNF protein]
CTD PMID:18455351 PMID:31018114 PMID:33901603 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type increases expression EXP Lithium Chloride results in increased expression of TNNC1 mRNA CTD PMID:23527032 NCBI chr 3:52,451,100...52,454,041
Ensembl chr 3:52,451,100...52,454,041
JBrowse link
G TNNT1 troponin T1, slow skeletal type increases expression EXP Lithium Chloride results in increased expression of TNNT1 mRNA CTD PMID:23527032 NCBI chr19:55,132,698...55,149,206
Ensembl chr19:55,132,698...55,149,206
JBrowse link
G TOP3A DNA topoisomerase III alpha decreases expression EXP Lithium Chloride results in decreased expression of TOP3A mRNA CTD PMID:23527032 NCBI chr17:18,271,428...18,314,994
Ensembl chr17:18,271,428...18,315,007
JBrowse link
G TP53 tumor protein p53 increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of TP53 protein
Lithium Chloride results in decreased degradation of and results in increased expression of TRP53 protein
CTD PMID:16055726 PMID:17210701 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TP63 tumor protein p63 increases expression EXP Lithium Chloride results in increased expression of TP63 mRNA CTD PMID:23527032 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276
JBrowse link
G TPD52L1 TPD52 like 1 increases expression EXP Lithium Chloride results in increased expression of TPD52L1 mRNA CTD PMID:23527032 NCBI chr 6:125,153,773...125,264,407
Ensembl chr 6:125,119,049...125,264,407
JBrowse link
G TPH1 tryptophan hydroxylase 1 decreases expression ISO Lithium Chloride results in decreased expression of TPH1 mRNA CTD PMID:33901603 NCBI chr11:18,017,555...18,046,269
Ensembl chr11:18,017,555...18,046,269
JBrowse link
G TPH2 tryptophan hydroxylase 2 decreases expression ISO Lithium Chloride results in decreased expression of TPH2 mRNA; Lithium Chloride results in decreased expression of TPH2 protein CTD PMID:19840776 NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618
JBrowse link
G TPM1 tropomyosin 1 increases expression EXP Lithium Chloride results in increased expression of TPM1 mRNA CTD PMID:23527032 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915
JBrowse link
G TRIB3 tribbles pseudokinase 3 increases expression EXP Lithium Chloride results in increased expression of TRIB3 mRNA CTD PMID:23527032 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
JBrowse link
G TRIM6 tripartite motif containing 6 increases expression EXP Lithium Chloride results in increased expression of TRIM6 mRNA CTD PMID:23527032 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958
JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase decreases expression
multiple interactions
EXP Lithium Chloride results in decreased expression of UGCG mRNA
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of UGCG mRNA
CTD PMID:15711924 PMID:26074776 NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369
JBrowse link
G UTP3 UTP3 small subunit processome component increases expression ISO Lithium Chloride results in increased expression of UTP3 mRNA CTD PMID:27226553 NCBI chr 4:70,688,532...70,690,551
Ensembl chr 4:70,688,532...70,690,551
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 increases expression ISO Lithium Chloride results in increased expression of VCAM1 mRNA CTD PMID:33901603 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G VCF2 VCP nuclear cofactor family member 2 decreases expression EXP Lithium Chloride results in decreased expression of VCF2 mRNA CTD PMID:23527032 NCBI chr  X:55,143,102...55,161,185
Ensembl chr  X:55,143,102...55,161,310
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression EXP
ISO
Lithium Chloride results in increased expression of VEGFA protein
Lithium Chloride results in increased expression of VEGFA mRNA
CTD PMID:20696143 PMID:26272751 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VIM vimentin increases expression
multiple interactions
decreases expression
ISO
EXP
Lithium Chloride results in increased expression of VIM protein
Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of VIM protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of VIM protein]
Lithium Chloride results in decreased expression of VIM mRNA
CTD PMID:8773480 PMID:23527032 PMID:32112862 PMID:35985571 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G VPREB1 V-set pre-B cell surrogate light chain 1 increases expression ISO Lithium Chloride results in increased expression of VPREB1 mRNA CTD PMID:27226553 NCBI chr22:22,244,786...22,245,515
Ensembl chr22:22,244,780...22,245,515
JBrowse link
G WNT1 Wnt family member 1 multiple interactions EXP Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of WNT1 protein] CTD PMID:28343033 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620
JBrowse link
G WNT3 Wnt family member 3 decreases expression ISO Lithium Chloride results in decreased expression of WNT3 mRNA CTD PMID:26272751 NCBI chr17:46,762,506...46,818,692
Ensembl chr17:46,762,506...46,833,154
JBrowse link
G XRCC4 X-ray repair cross complementing 4 increases expression ISO Lithium Chloride results in increased expression of XRCC4 mRNA CTD PMID:19285016 NCBI chr 5:83,077,547...83,374,473
Ensembl chr 5:83,077,498...83,353,787
JBrowse link
G YBX1 Y-box binding protein 1 decreases expression EXP Lithium Chloride results in decreased expression of YBX1 mRNA CTD PMID:23527032 NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805
JBrowse link
G ZMYND8 zinc finger MYND-type containing 8 decreases expression EXP Lithium Chloride results in decreased expression of ZMYND8 mRNA CTD PMID:15711924 NCBI chr20:47,209,214...47,356,699
Ensembl chr20:47,209,214...47,356,889
JBrowse link
G ZNF207 zinc finger protein 207 increases expression EXP Lithium Chloride results in increased expression of ZNF207 mRNA CTD PMID:15711924 NCBI chr17:32,350,157...32,381,885
Ensembl chr17:32,350,132...32,381,885
JBrowse link
G ZNF266 zinc finger protein 266 decreases expression EXP Lithium Chloride results in decreased expression of ZNF266 mRNA CTD PMID:23527032 NCBI chr19:9,412,429...9,435,573
Ensembl chr19:9,412,429...9,435,573
JBrowse link
G ZNF285 zinc finger protein 285 decreases expression EXP Lithium Chloride results in decreased expression of ZNF285 mRNA CTD PMID:23527032 NCBI chr19:44,382,298...44,401,608
Ensembl chr19:44,382,298...44,401,608
JBrowse link
G ZNF423 zinc finger protein 423 decreases expression EXP Lithium Chloride results in decreased expression of ZNF423 mRNA CTD PMID:23527032 NCBI chr16:49,487,524...49,859,279
Ensembl chr16:49,487,524...49,857,919
JBrowse link
G ZSCAN22 zinc finger and SCAN domain containing 22 decreases expression EXP Lithium Chloride results in decreased expression of ZSCAN22 mRNA CTD PMID:23527032 NCBI chr19:58,326,994...58,342,332
Ensembl chr19:58,326,994...58,342,332
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    chemical entity 26019
      molecular entity 25997
        inorganic molecular entity 25320
          inorganic salt 16307
            inorganic chloride 8161
              lithium chloride 366
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      halogen 21140
                        chlorine atom 20247
                          chlorine molecular entity 20247
                            elemental chlorine 8463
                              monoatomic chlorine 8446
                                chloride 8446
                                  chloride salt 8446
                                    inorganic chloride 8161
                                      lithium chloride 366
paths to the root