Gene: HSPA1A (heat shock 70kDa protein 1A)  Homo sapiens

Symbol: HSPA1A
Name: heat shock 70kDa protein 1A
Description: This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dnaK-type molecular chaperone HSP70-1; FLJ54303; FLJ54370; FLJ54392; FLJ54408; FLJ75127; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A/1B; heat shock 70kD protein 1A; heat shock-induced protein; HSP70; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70.1/HSP70.2; HSP70I; HSP72; HSPA1; HSPA1B; OTTHUMP00000029287
Orthologs: Mus musculus : Hspa1a (heat shock protein 1A)  MGI
Rattus norvegicus : Hspa1a (heat shock protein 1A)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1631,700,246 - 31,702,674+NCBI
Human Genome Assembly HuRef631,569,698 - 31,572,209+NCBI
Human Genome Assembly GRCh37631,783,291 - 31,785,719+NCBI
Human Genome Assembly Build 36631,891,316 - 31,893,698+NCBI
Human Cytogenetic Map6p21.3 NCBI
Human Genome Assembly631,891,315 - 31,893,698 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on HSPA1A
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1349475
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2013-05-14
Status: ACTIVE