PPP1R14C (protein phosphatase 1 regulatory inhibitor subunit 14C) - Rat Genome Database

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Gene: PPP1R14C (protein phosphatase 1 regulatory inhibitor subunit 14C) Homo sapiens
Analyze
Symbol: PPP1R14C
Name: protein phosphatase 1 regulatory inhibitor subunit 14C
RGD ID: 735966
HGNC Page HGNC:14952
Description: Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be located in cytoplasm and membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CPI17-like; KEPI; kinase C-enhanced PP1 inhibitor; kinase-enhanced PP1 inhibitor; NY-BR-81; PKC-potentiated PP1 inhibitory protein; protein phosphatase 1 regulatory subunit 14C; serologically defined breast cancer antigen NY-BR-81
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386150,143,044 - 150,250,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6150,143,044 - 150,250,392 (+)EnsemblGRCh38hg38GRCh38
GRCh376150,464,180 - 150,571,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366150,505,881 - 150,613,221 (+)NCBINCBI36Build 36hg18NCBI36
Build 346150,556,346 - 150,663,605NCBI
Celera6151,198,793 - 151,306,443 (+)NCBICelera
Cytogenetic Map6q25.1NCBI
HuRef6148,029,989 - 148,136,641 (+)NCBIHuRef
CHM1_16150,728,261 - 150,835,613 (+)NCBICHM1_1
T2T-CHM13v2.06151,342,372 - 151,450,366 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11564868   PMID:11812771   PMID:11948623   PMID:12477932   PMID:12747765   PMID:14574404   PMID:14702039   PMID:15489334   PMID:16449650   PMID:19132087   PMID:19475667   PMID:20592344  
PMID:21873635   PMID:21946350   PMID:22939629   PMID:23284291   PMID:26760575   PMID:28514442   PMID:29987050   PMID:30021884   PMID:33961781   PMID:34187934   PMID:35031423  


Genomics

Comparative Map Data
PPP1R14C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386150,143,044 - 150,250,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6150,143,044 - 150,250,392 (+)EnsemblGRCh38hg38GRCh38
GRCh376150,464,180 - 150,571,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366150,505,881 - 150,613,221 (+)NCBINCBI36Build 36hg18NCBI36
Build 346150,556,346 - 150,663,605NCBI
Celera6151,198,793 - 151,306,443 (+)NCBICelera
Cytogenetic Map6q25.1NCBI
HuRef6148,029,989 - 148,136,641 (+)NCBIHuRef
CHM1_16150,728,261 - 150,835,613 (+)NCBICHM1_1
T2T-CHM13v2.06151,342,372 - 151,450,366 (+)NCBIT2T-CHM13v2.0
Ppp1r14c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39103,315,974 - 3,414,975 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl103,316,057 - 3,414,975 (+)EnsemblGRCm39 Ensembl
GRCm38103,365,974 - 3,464,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl103,366,057 - 3,464,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv37106,881,566 - 6,980,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36106,881,566 - 6,980,391 (-)NCBIMGSCv36mm8
Celera103,301,562 - 3,400,112 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.06NCBI
Ppp1r14c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,177,977 - 42,358,654 (+)NCBIGRCr8
mRatBN7.2139,773,403 - 39,886,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl139,773,403 - 39,886,956 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx140,299,808 - 40,413,279 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,287,020 - 46,400,487 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0140,376,091 - 40,489,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0139,811,314 - 39,923,071 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl139,811,314 - 39,923,057 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0141,159,898 - 41,272,182 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4134,004,772 - 34,118,105 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1134,008,256 - 34,121,036 (+)NCBI
Celera135,478,909 - 35,591,445 (+)NCBICelera
Cytogenetic Map1p11NCBI
Ppp1r14c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543911,142,520 - 11,238,660 (-)NCBIChiLan1.0ChiLan1.0
PPP1R14C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25170,163,087 - 170,269,635 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16168,056,563 - 168,163,106 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06147,956,175 - 148,063,169 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16152,657,854 - 152,767,547 (+)NCBIpanpan1.1PanPan1.1panPan2
PPP1R14C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1140,710,826 - 40,797,413 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl140,710,992 - 40,795,889 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha141,549,480 - 41,635,462 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0140,892,922 - 40,979,148 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl140,892,922 - 40,978,116 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1140,768,624 - 40,854,688 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0140,612,465 - 40,698,436 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0141,116,047 - 41,202,074 (+)NCBIUU_Cfam_GSD_1.0
Ppp1r14c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946136,014,815 - 136,113,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364893,282,779 - 3,363,935 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364893,266,808 - 3,365,432 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R14C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl115,865,220 - 15,949,956 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1115,867,846 - 15,949,951 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2117,995,575 - 18,079,171 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R14C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11377,556,799 - 77,672,727 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1377,557,429 - 77,672,801 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604049,873,570 - 49,984,870 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r14c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247857,930,781 - 8,015,529 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247857,930,893 - 8,015,584 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPP1R14C
11 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q24.1-27(chr6:141132990-169339571)x3 copy number gain See cases [RCV000050604] Chr6:141132990..169339571 [GRCh38]
Chr6:141454127..169739666 [GRCh37]
Chr6:141495820..169481591 [NCBI36]
Chr6:6q24.1-27		 pathogenic
GRCh38/hg38 6q24.3-25.1(chr6:146481119-151427629)x1 copy number loss See cases [RCV000051005] Chr6:146481119..151427629 [GRCh38]
Chr6:146802255..151748764 [GRCh37]
Chr6:146843948..151790457 [NCBI36]
Chr6:6q24.3-25.1		 pathogenic
GRCh38/hg38 6q24.2-25.2(chr6:144932561-152985364)x1 copy number loss See cases [RCV000052206] Chr6:144932561..152985364 [GRCh38]
Chr6:145253697..153306499 [GRCh37]
Chr6:145295390..153348192 [NCBI36]
Chr6:6q24.2-25.2		 pathogenic
GRCh38/hg38 6q24.3-25.1(chr6:147805119-150893715)x1 copy number loss See cases [RCV000135408] Chr6:147805119..150893715 [GRCh38]
Chr6:148126255..151214851 [GRCh37]
Chr6:148167948..151256544 [NCBI36]
Chr6:6q24.3-25.1		 pathogenic
GRCh38/hg38 6q23.3-25.3(chr6:135358150-155455117)x3 copy number gain See cases [RCV000136826] Chr6:135358150..155455117 [GRCh38]
Chr6:135679288..155776251 [GRCh37]
Chr6:135720981..155817943 [NCBI36]
Chr6:6q23.3-25.3		 pathogenic
GRCh38/hg38 6q24.3-25.1(chr6:147580351-150227963)x3 copy number gain See cases [RCV000138362] Chr6:147580351..150227963 [GRCh38]
Chr6:147901487..150549099 [GRCh37]
Chr6:147943180..150590792 [NCBI36]
Chr6:6q24.3-25.1		 uncertain significance
GRCh38/hg38 6q23.2-27(chr6:133537271-165875545)x3 copy number gain See cases [RCV000143444] Chr6:133537271..165875545 [GRCh38]
Chr6:133858409..166289033 [GRCh37]
Chr6:133900102..166209023 [NCBI36]
Chr6:6q23.2-27		 pathogenic
GRCh37/hg19 6q24.2-25.1(chr6:144075695-152337005)x1 copy number loss See cases [RCV000448815] Chr6:144075695..152337005 [GRCh37]
Chr6:6q24.2-25.1		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6q25.1-27(chr6:150284435-170919470)x3 copy number gain not provided [RCV000746100] Chr6:150284435..170919470 [GRCh37]
Chr6:6q25.1-27		 pathogenic
GRCh37/hg19 6q24.3-25.1(chr6:148690764-150494873)x1 copy number loss See cases [RCV000790589] Chr6:148690764..150494873 [GRCh37]
Chr6:6q24.3-25.1		 pathogenic
GRCh37/hg19 6q25.1-25.2(chr6:149431322-154120064)x1 copy number loss not provided [RCV001005856] Chr6:149431322..154120064 [GRCh37]
Chr6:6q25.1-25.2		 pathogenic
GRCh37/hg19 6q24.3-25.3(chr6:148195086-160127254)x3 copy number gain not provided [RCV000846496] Chr6:148195086..160127254 [GRCh37]
Chr6:6q24.3-25.3		 pathogenic
NM_030949.3(PPP1R14C):c.143C>A (p.Ala48Glu) single nucleotide variant Inborn genetic diseases [RCV002836728] Chr6:150143335 [GRCh38]
Chr6:150464471 [GRCh37]
Chr6:6q25.1		 uncertain significance
NM_030949.3(PPP1R14C):c.112A>G (p.Ser38Gly) single nucleotide variant Inborn genetic diseases [RCV002992617] Chr6:150143304 [GRCh38]
Chr6:150464440 [GRCh37]
Chr6:6q25.1		 uncertain significance
NM_030949.3(PPP1R14C):c.80G>A (p.Arg27Gln) single nucleotide variant Inborn genetic diseases [RCV002869814] Chr6:150143272 [GRCh38]
Chr6:150464408 [GRCh37]
Chr6:6q25.1		 uncertain significance
NM_030949.3(PPP1R14C):c.160G>A (p.Ala54Thr) single nucleotide variant Inborn genetic diseases [RCV003004404] Chr6:150143352 [GRCh38]
Chr6:150464488 [GRCh37]
Chr6:6q25.1		 uncertain significance
NM_030949.3(PPP1R14C):c.148G>T (p.Val50Leu) single nucleotide variant Inborn genetic diseases [RCV002714083] Chr6:150143340 [GRCh38]
Chr6:150464476 [GRCh37]
Chr6:6q25.1		 uncertain significance
NM_030949.3(PPP1R14C):c.304G>A (p.Glu102Lys) single nucleotide variant Inborn genetic diseases [RCV003344352] Chr6:150143496 [GRCh38]
Chr6:150464632 [GRCh37]
Chr6:6q25.1		 uncertain significance
NM_030949.3(PPP1R14C):c.282G>C (p.Gln94His) single nucleotide variant Inborn genetic diseases [RCV003369501] Chr6:150143474 [GRCh38]
Chr6:150464610 [GRCh37]
Chr6:6q25.1		 uncertain significance
GRCh37/hg19 6q22.31-25.3(chr6:119840686-156623091)x3 copy number gain not specified [RCV003986631] Chr6:119840686..156623091 [GRCh37]
Chr6:6q22.31-25.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:532
Count of miRNA genes:443
Interacting mature miRNAs:470
Transcripts:ENST00000361131
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WIAF-1701  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,571,203 - 150,571,343UniSTSGRCh37
Build 366150,612,896 - 150,613,036RGDNCBI36
Celera6151,306,118 - 151,306,258RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,136,316 - 148,136,456UniSTS
GeneMap99-GB4 RH Map6594.98UniSTS
RH37413  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,506,347 - 150,506,472UniSTSGRCh37
Build 366150,548,040 - 150,548,165RGDNCBI36
Celera6151,240,954 - 151,241,079RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,072,021 - 148,072,146UniSTS
GeneMap99-GB4 RH Map6598.84UniSTS
NCBI RH Map61598.0UniSTS
RH18265  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,570,170 - 150,570,327UniSTSGRCh37
Build 366150,611,863 - 150,612,020RGDNCBI36
Celera6151,305,085 - 151,305,242RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,135,283 - 148,135,440UniSTS
GeneMap99-GB4 RH Map6598.74UniSTS
RH47324  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,570,363 - 150,570,456UniSTSGRCh37
Build 366150,612,056 - 150,612,149RGDNCBI36
Celera6151,305,278 - 151,305,371RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,135,476 - 148,135,569UniSTS
GeneMap99-GB4 RH Map6598.74UniSTS
RH37415  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,500,665 - 150,500,788UniSTSGRCh37
Build 366150,542,358 - 150,542,481RGDNCBI36
Celera6151,235,272 - 151,235,395RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,066,339 - 148,066,462UniSTS
GeneMap99-GB4 RH Map6598.74UniSTS
D6S1178E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,571,218 - 150,571,346UniSTSGRCh37
Build 366150,612,911 - 150,613,039RGDNCBI36
Celera6151,306,133 - 151,306,261RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,136,331 - 148,136,459UniSTS
GeneMap99-GB4 RH Map6589.78UniSTS
RH18363  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,571,226 - 150,571,351UniSTSGRCh37
Build 366150,612,919 - 150,613,044RGDNCBI36
Celera6151,306,141 - 151,306,266RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,136,339 - 148,136,464UniSTS
GeneMap99-GB4 RH Map6598.53UniSTS
WI-22584  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,570,361 - 150,570,462UniSTSGRCh37
Build 366150,612,054 - 150,612,155RGDNCBI36
Celera6151,305,276 - 151,305,377RGD
Cytogenetic Map6q24.3-q25.3UniSTS
HuRef6148,135,474 - 148,135,575UniSTS
GeneMap99-GB4 RH Map6598.74UniSTS
Whitehead-RH Map6811.7UniSTS
PPP1R14C_2476  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376150,570,830 - 150,571,623UniSTSGRCh37
Build 366150,612,523 - 150,613,316RGDNCBI36
Celera6151,305,745 - 151,306,538RGD
HuRef6148,135,943 - 148,136,736UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 349 839 718 38 36 18 2125 1150 826 190 638 1186 35 3 1475 2
Low 661 1172 323 118 311 27 1261 253 2422 175 479 363 91 1 354 831 2 1
Below cutoff 1362 890 477 286 1125 239 943 745 447 49 315 34 47 821 476 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000361131   ⟹   ENSP00000355260
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6150,143,044 - 150,250,392 (+)Ensembl
RefSeq Acc Id: NM_030949   ⟹   NP_112211
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386150,143,044 - 150,250,392 (+)NCBI
GRCh376150,464,188 - 150,571,528 (+)RGD
Build 366150,505,881 - 150,613,221 (+)NCBI Archive
Celera6151,198,793 - 151,306,443 (+)RGD
HuRef6148,029,989 - 148,136,641 (+)ENTREZGENE
CHM1_16150,728,261 - 150,835,613 (+)NCBI
T2T-CHM13v2.06151,342,372 - 151,450,366 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_112211   ⟸   NM_030949
- UniProtKB: Q96BB1 (UniProtKB/Swiss-Prot),   Q5VY83 (UniProtKB/Swiss-Prot),   Q9H277 (UniProtKB/Swiss-Prot),   Q8TAE6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000355260   ⟸   ENST00000361131

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8TAE6-F1-model_v2 AlphaFold Q8TAE6 1-165 view protein structure

Promoters
RGD ID:7209433
Promoter ID:EPDNEW_H10462
Type:initiation region
Name:PPP1R14C_1
Description:protein phosphatase 1 regulatory inhibitor subunit 14C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386150,143,044 - 150,143,104EPDNEW
RGD ID:6804557
Promoter ID:HG_KWN:55419
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000361131
Position:
Human AssemblyChrPosition (strand)Source
Build 366150,505,636 - 150,506,136 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14952 AgrOrtholog
COSMIC PPP1R14C COSMIC
Ensembl Genes ENSG00000198729 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000361131 ENTREZGENE
  ENST00000361131.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.220 UniProtKB/Swiss-Prot
GTEx ENSG00000198729 GTEx
HGNC ID HGNC:14952 ENTREZGENE
Human Proteome Map PPP1R14C Human Proteome Map
InterPro CPI-17 UniProtKB/Swiss-Prot
  CPI-17_sf UniProtKB/Swiss-Prot
KEGG Report hsa:81706 UniProtKB/Swiss-Prot
NCBI Gene 81706 ENTREZGENE
OMIM 613242 OMIM
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C UniProtKB/Swiss-Prot
  PTHR16188 UniProtKB/Swiss-Prot
Pfam PP1_inhibitor UniProtKB/Swiss-Prot
PharmGKB PA33630 PharmGKB
Superfamily-SCOP SSF81790 UniProtKB/Swiss-Prot
UniProt L8EAF9_HUMAN UniProtKB/TrEMBL
  PP14C_HUMAN UniProtKB/Swiss-Prot
  Q5VY83 ENTREZGENE
  Q8TAE6 ENTREZGENE
  Q96BB1 ENTREZGENE
  Q9H277 ENTREZGENE
UniProt Secondary Q5VY83 UniProtKB/Swiss-Prot
  Q96BB1 UniProtKB/Swiss-Prot
  Q9H277 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 PPP1R14C  protein phosphatase 1 regulatory inhibitor subunit 14C    protein phosphatase 1, regulatory (inhibitor) subunit 14C  Symbol and/or name change 5135510 APPROVED