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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of translational initiation
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Accession:GO:0006446 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of translational initiation.


show annotations for term's descendants           Sort by:
regulation of translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO (PMID:27745969) RGD PMID:27745969 NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
G Bc1 brain cytoplasmic RNA 1 IDA RGD PMID:12451124 RGD:628491 NCBI chr 1:200,073,610...200,073,763 JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 involved_in ISO
ISS		 (PMID:29470543), (PMID:34260931)
GO_REF:0000024		 RGD
UniProt		 PMID:29470543 PMID:34260931 GO_REF:0000024 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430 		JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 involved_in ISO
ISS		 (PMID:21745818), (PMID:28981728), (PMID:29470543), (PMID:34260931)
GO_REF:0000024		 RGD
UniProt		 PMID:21745818 PMID:28981728 PMID:29470543 PMID:34260931 GO_REF:0000024 NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628 		JBrowse link
G Ctif cap binding complex dependent translation initiation factor involved_in ISO
IBA		 (PMID:19648179)
PMID:21873635		 RGD PMID:19648179 PMID:21873635 RGD:13792537 NCBI chr18:69,056,151...69,327,361
Ensembl chr18:69,059,519...69,327,385 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 involved_in ISO (PMID:22156057) RGD PMID:22156057 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B involved_in ISO
ISS		 (PMID:8995410)
GO_REF:0000024		 RGD
UniProt		 PMID:8995410 GO_REF:0000024 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3k eukaryotic translation initiation factor 3, subunit K involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:84,260,125...84,270,051
Ensembl chr 1:84,259,673...84,270,302 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 involved_in ISO (PMID:19648179) RGD PMID:19648179 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 involved_in ISO (PMID:11943866)
(MGI:85696|PMID:9030685)		 RGD PMID:9030685 PMID:11943866 MGI:85696 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 involved_in ISO (PMID:22156057) RGD PMID:22156057 NCBI chr 6:130,589,200...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B involved_in ISO (PMID:10432305) RGD PMID:10432305 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482 		JBrowse link
G Impact impact RWD domain protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3589702|PMID:15937339)		 RGD PMID:15937339 PMID:21873635 MGI:3589702, RGD:13792537 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
G Klhl25 kelch-like family member 25 involved_in ISO
ISS		 (PMID:22578813)
GO_REF:0000024		 RGD
UniProt		 PMID:22578813 GO_REF:0000024 NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227 		JBrowse link
G Mif4gd MIF4G domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:100,847,168...100,852,166 JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 IMP RGD PMID:17510413 PMID:16955078 RGD:8553009, RGD:8553011 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 involved_in ISO
ISS		 (PMID:11551508)
GO_REF:0000024		 RGD
UniProt		 PMID:11551508 GO_REF:0000024 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 involved_in ISO (PMID:11551508) RGD PMID:11551508 NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:51,523,142...51,550,241
Ensembl chr 2:51,522,921...51,550,241 		JBrowse link
eiF2alpha phosphorylation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6467680|PMID:17707796)
(PMID:25329545)		 UniProt
RGD		 PMID:17707796 PMID:25329545 GO_REF:0000024 MGI:6467680 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (PMID:25329545) RGD PMID:25329545 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO
ISS		 (PMID:22064321)
(MGI:5617428|PMID:25329545)
GO_REF:0000024		 RGD
UniProt		 PMID:22064321 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213), (PMID:16835242)
PMID:21873635
UniProtKB:O55033 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)		 RGD PMID:14676213 PMID:16835242 PMID:21873635 MGI:5613475 MGI:5613478, RGD:13792537 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 (PMID:16835242)
PMID:21873635
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)		 RGD PMID:14676213 PMID:16835242 PMID:21873635 MGI:5613475 MGI:5613478, RGD:13792537 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO MGI:4456438 (MGI:5914333|PMID:28797121) RGD PMID:28797121 MGI:5914333 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
negative regulation of formation of translation preinitiation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl13a ribosomal protein L13A involved_in ISO
ISS		 (PMID:17218275)
GO_REF:0000024		 RGD
UniProt		 PMID:17218275 GO_REF:0000024 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
negative regulation of translation in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pml PML nuclear body scaffold involved_in ISO (PMID:16915281) RGD PMID:16915281 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
negative regulation of translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC112866.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:179,077,601...179,077,975 JBrowse link
G Ago2 argonaute RISC catalytic component 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17524464), (PMID:19801630)
GO_REF:0000104		 UniProt
RGD		 PMID:17524464 PMID:19801630 GO_REF:0000024 GO_REF:0000104 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Bank1 B-cell scaffold protein with ankyrin repeats 1 acts_upstream_of_or_within ISO MGI:3686872 (MGI:5554491|PMID:24227780) RGD PMID:24227780 MGI:5554491 NCBI chr 2:224,530,475...224,800,420
Ensembl chr 2:224,530,475...224,800,405 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5700304|PMID:16601681)		 UniProt
RGD		 PMID:16601681 GO_REF:0000024 MGI:5700304 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 involved_in
acts_upstream_of_or_within		 IMP
IEA
ISO
IBA		 GO_REF:0000002
(MGI:3604839|PMID:16142217)
PMID:21873635
(PMID:22578813)		 InterPro
RGD		 PMID:16142217 PMID:22578813 PMID:11865047 PMID:21873635 GO_REF:0000002 MGI:3604839, RGD:1625627, RGD:13792537 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 involved_in IBA
ISO		 PMID:21873635
(PMID:30765518)
(MGI:3607012|PMID:16237163), (MGI:4820682|PMID:20347422), (MGI:5471212|PMID:23172145)		 RGD PMID:16237163 PMID:20347422 PMID:23172145 PMID:30765518 PMID:21873635 MGI:3607012 MGI:4820682 MGI:5471212, RGD:13792537 NCBI chr20:29,379,444...29,400,131
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4418608|PMID:18805096)		 UniProt
RGD		 PMID:18805096 GO_REF:0000024 MGI:4418608 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO (PMID:28379136) RGD PMID:28379136 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371 		JBrowse link
G Paip2 poly(A) binding protein interacting protein 2 involved_in ISO
IEA		 (PMID:11172725)
GO_REF:0000002		 RGD
InterPro		 PMID:11172725 GO_REF:0000002 NCBI chr18:27,199,762...27,218,359
Ensembl chr18:27,199,796...27,214,863 		JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B involved_in ISO (PMID:16804161) RGD PMID:16804161 NCBI chr 4:116,291,376...116,323,422
Ensembl chr 4:116,292,020...116,323,379 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within ISO (MGI:3803427|PMID:18495661) RGD PMID:18495661 MGI:3803427 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rbm4 RNA binding motif protein 4 involved_in ISO (PMID:19801630) RGD PMID:19801630 NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:34535749) RGD PMID:34535749 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:21613532)		 UniProt
RGD		 PMID:21613532 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
negative regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (MGI:5700311|PMID:12176355) RGD PMID:12176355 MGI:5700311 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:5700311|PMID:12176355)		 UniProt
RGD		 PMID:12176355 GO_REF:0000024 MGI:5700311 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
positive regulation of cap-dependent translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:11959995) RGD PMID:11959995 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
positive regulation of cap-independent translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (PMID:26593424) RGD PMID:26593424 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:11959995) RGD PMID:11959995 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:26458103) RGD PMID:26458103 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
positive regulation of cytoplasmic translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh3bgrl1 SH3 domain binding glutamate rich protein like 1 involved_in ISO (PMID:34331014) RGD PMID:34331014 NCBI chr  X:74,167,029...74,263,783
Ensembl chr  X:74,166,871...74,263,783 		JBrowse link
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:21518769) RGD PMID:21518769 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
positive regulation of translation initiation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5617428|PMID:25329545)		 UniProt
RGD		 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
positive regulation of translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Boll boule homolog, RNA binding protein involved_in ISO
IBA		 (PMID:16001084)
PMID:21873635		 RGD PMID:16001084 PMID:21873635 RGD:13792537 NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916 		JBrowse link
G Dazl deleted in azoospermia-like involved_in ISO
IBA		 (PMID:16001084)
PMID:21873635
(MGI:3689792|PMID:16001084)		 RGD PMID:16001084 PMID:21873635 MGI:3689792, RGD:13792537 NCBI chr 9:10,695,572...10,712,443
Ensembl chr 9:10,695,592...10,712,323 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:20837705) RGD PMID:20837705 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx29 DExH-box helicase 29 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:44,560,653...44,611,450
Ensembl chr 2:44,560,714...44,611,445 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Habp4 hyaluronan binding protein 4 involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:21771594)		 UniProt
RGD		 PMID:21771594 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21613532)		 UniProt
RGD		 PMID:21613532 GO_REF:0000024 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO (PMID:29244122) RGD PMID:29244122 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:22578813) RGD PMID:22578813 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Polr2g RNA polymerase II subunit G involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:205,689,160...205,692,537
Ensembl chr 1:205,689,160...205,692,686 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 involved_in ISO (PMID:16763566) RGD PMID:16763566 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 involved_in ISO (PMID:16763566) RGD PMID:16763566 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078 		JBrowse link
G Uhmk1 U2AF homology motif kinase 1 involved_in ISO
IEA
IBA		 (MGI:3835232|PMID:19015237)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:19015237 PMID:21873635 GO_REF:0000107 MGI:3835232, RGD:13792537 NCBI chr13:82,396,646...82,416,292
Ensembl chr13:82,401,187...82,416,292 		JBrowse link
G Ythdf1 YTH N6-methyladenosine RNA binding protein F1 NOT|involved_in ISO (PMID:32492408)
(MGI:6490006|PMID:32943573)
(PMID:26046440)		 RGD PMID:26046440 PMID:32492408 PMID:32943573 MGI:6490006 NCBI chr 3:168,024,660...168,040,172
Ensembl chr 3:168,024,663...168,040,172 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 NOT|involved_in ISO (PMID:32492408)
(MGI:6490006|PMID:32943573)		 RGD PMID:32492408 PMID:32943573 MGI:6490006 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 NOT|involved_in ISO (PMID:32492408)
(MGI:6490006|PMID:32943573)
(PMID:28106076)		 RGD PMID:28106076 PMID:32492408 PMID:32943573 MGI:6490006 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
positive regulation of translational initiation by iron term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha acts_upstream_of_or_within ISO MGI:1201686 (MGI:5538466|PMID:23775127) RGD PMID:23775127 MGI:5538466 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (MGI:2152007|PMID:11588035) RGD PMID:11588035 MGI:2152007 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
positive regulation of translational initiation in response to starvation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2149467|PMID:10655230), (MGI:3589053|PMID:16121183)		 UniProt
RGD		 PMID:10655230 PMID:16121183 GO_REF:0000024 MGI:2149467 MGI:3589053 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Impact impact RWD domain protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5494763|PMID:23447528)		 UniProt
RGD		 PMID:23447528 GO_REF:0000024 MGI:5494763 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
regulation of cytoplasmic translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Impact impact RWD domain protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5576818|PMID:24333428)		 UniProt
RGD		 PMID:24333428 GO_REF:0000024 MGI:5576818 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
regulation of eIF2 alpha phosphorylation by dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:12882984)
GO_REF:0000024		 RGD
UniProt		 PMID:12882984 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
regulation of eIF2 alpha phosphorylation by heme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1353448|MGI:95513 (MGI:3581470|PMID:15931390)
GO_REF:0000107		 RGD
Ensembl		 PMID:15931390 GO_REF:0000107 MGI:3581470 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1353448|MGI:1858114|MGI:95513 (MGI:3581470|PMID:15931390) RGD PMID:15931390 MGI:3581470 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hbb hemoglobin subunit beta acts_upstream_of_or_within ISO MGI:1857179 (MGI:3581470|PMID:15931390) RGD PMID:15931390 MGI:3581470 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3582244|PMID:11106749)		 UniProt
RGD		 PMID:11106749 GO_REF:0000024 MGI:3582244 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:5605960 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
regulation of translational initiation by eIF2 alpha dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:12556489) RGD PMID:12556489 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
regulation of translational initiation by eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:1858648|PMID:10882126), (MGI:3582244|PMID:11106749), (MGI:3722921|PMID:14729979), (MGI:5613478|PMID:14676213) RGD PMID:10882126 PMID:11106749 PMID:14676213 PMID:14729979 MGI:1858648 MGI:3582244 MGI:3722921 MGI:5613478 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000002
UniProtKB:Q9Z2B5 (MGI:2149467|PMID:10655230), (MGI:3582244|PMID:11106749), (MGI:3589053|PMID:16121183), (MGI:3722921|PMID:14729979), (MGI:5700278|PMID:26102367), (MGI:5700304|PMID:16601681), (MGI:5700311|PMID:12176355)
(PMID:26102367)		 UniProt
InterPro
RGD		 PMID:10655230 PMID:11106749 PMID:12176355 PMID:14729979 PMID:16121183 More... GO_REF:0000002 GO_REF:0000024 MGI:2149467 MGI:3582244 MGI:3589053 MGI:3722921 MGI:5700278 MGI:5700304 MGI:5700311 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 acts_upstream_of_or_within ISO (MGI:3589702|PMID:15937339) RGD PMID:15937339 MGI:3589702 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha acts_upstream_of_or_within ISO (MGI:3589702|PMID:15937339) RGD PMID:15937339 MGI:3589702 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    cellular process 17330
      cellular metabolic process 7444
        translational initiation 131
          regulation of translational initiation 69
            negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 6
            negative regulation of translational initiation + 19
            positive regulation of translational initiation + 24
            regulation of cytoplasmic translational initiation + 6
            regulation of eIF2 alpha phosphorylation by dsRNA 1
            regulation of eIF2 alpha phosphorylation by heme 3
            regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation + 1
            regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 2
            regulation of mitochondrial translational initiation + 0
            regulation of translational initiation by iron + 2
            regulation of translational initiation in response to stress + 16
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      cellular metabolic process 7444
        cellular nitrogen compound metabolic process 3961
          cellular nitrogen compound biosynthetic process 2198
            amide biosynthetic process 1362
              peptide biosynthetic process 1232
                translation 1209
                  translational initiation 131
                    regulation of translational initiation 69
                      negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 6
                      negative regulation of translational initiation + 19
                      positive regulation of translational initiation + 24
                      regulation of cytoplasmic translational initiation + 6
                      regulation of eIF2 alpha phosphorylation by dsRNA 1
                      regulation of eIF2 alpha phosphorylation by heme 3
                      regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation + 1
                      regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 2
                      regulation of mitochondrial translational initiation + 0
                      regulation of translational initiation by iron + 2
                      regulation of translational initiation in response to stress + 16
paths to the root