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ONTOLOGY REPORT - ANNOTATIONS

Term:eiF2alpha phosphorylation in response to endoplasmic reticulum stress
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Accession:GO:0036492 term browser browse the term
Definition:The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.
Synonyms:exact_synonym: eiF2alpha phosphorylation in response to ER stress;   regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress


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negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO
ISS		 (PMID:22064321)
GO_REF:0000024
(MGI:5617428|PMID:25329545)		 RGD
UniProt		 PMID:22064321 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213)
UniProtKB:O55033 (MGI:5613478|PMID:14676213)
GO_REF:0000033		 RGD
GO_Central		 PMID:14676213 GO_REF:0000033 MGI:5613478 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 UniProtKB:Q99M51 (MGI:5613478|PMID:14676213)
GO_REF:0000033		 RGD
GO_Central		 PMID:14676213 GO_REF:0000033 MGI:5613478 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4456438 (PMID:28797121)		 Ensembl
RGD		 PMID:28797121 GO_REF:0000107 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3582244|PMID:11106749)		 UniProt
RGD		 PMID:11106749 GO_REF:0000024 MGI:3582244 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:5605960 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10920
      response to stress 4281
        cellular response to stress 2061
          regulation of translation in response to stress 23
            regulation of translational initiation in response to stress 14
              regulation of translational initiation by eIF2 alpha phosphorylation 10
                eiF2alpha phosphorylation in response to endoplasmic reticulum stress 6
                  negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 4
                  regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 2
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of metabolic process 6641
          regulation of biosynthetic process 5478
            regulation of cellular biosynthetic process 5386
              regulation of macromolecule biosynthetic process 5286
                regulation of gene expression 5170
                  post-transcriptional regulation of gene expression 784
                    regulation of translation 497
                      regulation of translational initiation 71
                        regulation of translational initiation in response to stress 14
                          regulation of translational initiation by eIF2 alpha phosphorylation 10
                            eiF2alpha phosphorylation in response to endoplasmic reticulum stress 6
                              negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 4
                              regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 2
paths to the root