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ONTOLOGY REPORT - ANNOTATIONS

Term:activated T cell proliferation
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Accession:GO:0050798 term browser browse the term
Definition:The expansion of a T cell population following activation by an antigenic stimulus.
Comment:Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.
Synonyms:exact_synonym: activated T lymphocyte proliferation;   proliferation of activated T cells


show annotations for term's descendants           Sort by:
activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:3525886 (PMID:18025176) RGD PMID:18025176 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Cadm1 cell adhesion molecule 1 NOT|involved_in ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule NOT|involved_in ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Ephb6 Eph receptor B6 acts_upstream_of_or_within ISO MGI:3522020 (PMID:15599401) RGD PMID:15599401 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179145 (PMID:1516132)		 Ensembl
RGD		 PMID:1516132 GO_REF:0000107 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2669956 (PMID:18971390)		 Ensembl
RGD		 PMID:18971390 GO_REF:0000107 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO MGI:1857191 (PMID:10485657), (PMID:1830926), (PMID:7584142) RGD PMID:1830926 PMID:7584142 PMID:10485657 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of ISO MGI:1857192 (PMID:7584142) RGD PMID:7584142 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:10485657), (PMID:9841920) RGD PMID:9841920 PMID:10485657 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Itgad integrin subunit alpha D acts_upstream_of_or_within ISO MGI:3579559 (PMID:15210787) RGD PMID:15210787 NCBI chr 1:182,759,762...182,788,422
Ensembl chr 1:182,759,740...182,788,161 		JBrowse link
G Itgal integrin subunit alpha L acts_upstream_of_or_within ISO MGI:2661083 (PMID:15210787) RGD PMID:15210787 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Itgam integrin subunit alpha M acts_upstream_of_or_within ISO MGI:2157556 (PMID:15210787) RGD PMID:15210787 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgax integrin subunit alpha X NOT|acts_upstream_of_or_within ISO MGI:3579560 (PMID:15210787) RGD PMID:15210787 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698 		JBrowse link
G Itgb2 integrin subunit beta 2 acts_upstream_of_or_within ISO MGI:1861705 (PMID:15210787) RGD PMID:15210787 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Satb1 SATB homeobox 1 acts_upstream_of_or_within ISO MGI:2386676 (PMID:15814699) RGD PMID:15814699 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of ISO MGI:103035 (PMID:10072077), (PMID:10485657) RGD PMID:10072077 PMID:10485657 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:103036|MGI:2181592 (PMID:10072077), (PMID:10485657), (PMID:9841920)		 Ensembl
RGD		 PMID:9841920 PMID:10072077 PMID:10485657 GO_REF:0000107 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
negative regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19360123)		 Ensembl
RGD		 PMID:19360123 GO_REF:0000107 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within
involved_in		 ISO (PMID:23589618)
(PMID:20208008)		 RGD PMID:20208008 PMID:23589618 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within ISO MGI:2178778 (PMID:12970760) RGD PMID:12970760 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:12538684)
(PMID:17489864)		 RGD PMID:12538684 PMID:17489864 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:18329370) RGD PMID:18329370 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3505776 (PMID:18077788)		 Ensembl
RGD		 PMID:18077788 GO_REF:0000107 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) RGD PMID:18619870 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23817958) RGD PMID:23817958 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lrrc32 leucine rich repeat containing 32 acts_upstream_of_or_within ISO (PMID:18628982) RGD PMID:18628982 NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373 		JBrowse link
G Mir181c microRNA 181c acts_upstream_of ISO (PMID:21112091) RGD PMID:21112091 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 involved_in ISO (PMID:12538684) RGD PMID:12538684 NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha involved_in ISO
IEA		 (PMID:17911601)
GO_REF:0000107		 RGD
Ensembl		 PMID:17911601 GO_REF:0000107 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prnp prion protein involved_in ISO (PMID:20145049) RGD PMID:20145049 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (PMID:18172933) RGD PMID:18172933 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:18329370) RGD PMID:18329370 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
positive regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA		 (PMID:15944249)
GO_REF:0000107		 RGD
Ensembl		 PMID:15944249 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Cd24 CD24 molecule involved_in ISO
ISS		 (PMID:11272271)
GO_REF:0000024		 RGD
UniProt		 PMID:11272271 PMID:11272271 GO_REF:0000024, RGD:8554145 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd86 CD86 molecule IDA RGD PMID:9237108 RGD:632472 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Epo erythropoietin IDA RGD PMID:21649646 RGD:10401062 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO		 GO_REF:0000024
(PMID:21876153)		 UniProt
RGD		 PMID:21876153 GO_REF:0000024 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2669956 (PMID:18971390)		 Ensembl
RGD		 PMID:18971390 GO_REF:0000107 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Hhla2 HHLA2 member of B7 family involved_in ISO (PMID:23784006) RGD PMID:23784006 NCBI chr11:51,257,681...51,271,408 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15944249) RGD PMID:15944249 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:15694994)
GO_REF:0000107		 RGD
Ensembl		 PMID:15694994 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 involved_in ISO
IBA		 (PMID:15694994)
GO_REF:0000033		 RGD
GO_Central		 PMID:15694994 GO_REF:0000033 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 involved_in ISO
ISS		 (PMID:15694994)
GO_REF:0000024		 RGD
UniProt		 PMID:15694994 GO_REF:0000024 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:11114383), (PMID:1674604) RGD PMID:1674604 PMID:11114383 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:11114383) RGD PMID:11114383 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISS
ISO		 GO_REF:0000107
PMID:8766574
(PMID:8766574)		 Ensembl
RGD		 PMID:8766574 PMID:8766574 GO_REF:0000107, RGD:8554620 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:10072077), (PMID:1830926)
MGI:1857191 (PMID:10485657), (PMID:1830926), (PMID:7584142)		 RGD PMID:1830926 PMID:7584142 PMID:10072077 PMID:10485657 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:11114383) RGD PMID:11114383 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1857192 (PMID:7584142) RGD PMID:7584142 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10485657), (PMID:9841920) RGD PMID:9841920 PMID:10485657 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Jak3 Janus kinase 3 IMP RGD PMID:11781254 RGD:1600262 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Mir21 microRNA 21 involved_in ISO RNAcentral:URS00005165DA_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir30b microRNA 30b involved_in ISO RNAcentral:URS000039ED8D_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:8627154)		 UniProt
RGD		 PMID:8627154 GO_REF:0000024 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:21892172) RGD PMID:21892172 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:9126961) RGD PMID:9126961 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035 (PMID:10072077), (PMID:10485657) RGD PMID:10072077 PMID:10485657 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103036|MGI:2181592 (PMID:10072077), (PMID:10485657), (PMID:9841920)		 Ensembl
RGD		 PMID:9841920 PMID:10072077 PMID:10485657 GO_REF:0000107 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Tnfsf4 TNF superfamily member 4 IDA RGD PMID:9790919 RGD:634509 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tnfsf9 TNF superfamily member 9 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:19187795 GO_REF:0000033, RGD:2317344 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345 		JBrowse link
regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule NOT|involved_in ISO (PMID:24187568), (PMID:25310899) RGD PMID:24187568 PMID:25310899 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Icam1 intercellular adhesion molecule 1 NOT|involved_in ISO (PMID:25310899) RGD PMID:25310899 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 NOT|involved_in ISO (PMID:25310899) RGD PMID:25310899 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q61160 (PMID:21876153)		 UniProt
RGD		 PMID:21876153 GO_REF:0000024 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    immune system process 3002
      leukocyte activation 1056
        lymphocyte activation 856
          lymphocyte proliferation 338
            T cell proliferation 249
              activated T cell proliferation 57
                negative regulation of activated T cell proliferation 16
                positive regulation of activated T cell proliferation 29
                regulation of activated T cell proliferation + 47
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      cell activation 1211
        leukocyte activation 1056
          lymphocyte activation 856
            T cell activation 607
              T cell proliferation 249
                activated T cell proliferation 57
                  negative regulation of activated T cell proliferation 16
                  positive regulation of activated T cell proliferation 29
                  regulation of activated T cell proliferation + 47
paths to the root