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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of fatty acid biosynthetic process
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Accession:GO:0042304 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.
Synonyms:exact_synonym: regulation of fatty acid anabolism;   regulation of fatty acid biosynthesis;   regulation of fatty acid formation;   regulation of fatty acid synthesis



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regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif6 eukaryotic translation initiation factor 6 involved_in ISS
ISO
GO_REF:0000024
(PMID:26383020)
UniProt
RGD
PMID:26383020 GO_REF:0000024 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G Gip gastric inhibitory polypeptide involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19627255)
GO_REF:0000107
(PMID:21852536)
UniProt
RGD
Ensembl
PMID:19627255 PMID:21852536 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Scap SREBF chaperone acts_upstream_of_or_within ISO MGI:2148743|MGI:2180899 (PMID:16054043) RGD PMID:16054043 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (PMID:15639194) RGD PMID:15639194 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) RGD PMID:15576844 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:11060345), (PMID:18635818) RGD PMID:11060345 PMID:18635818 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
ISS
(PMID:16326698)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16326698 GO_REF:0000024 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:99,171,506...99,260,183
Ensembl chr 6:99,171,506...99,260,110
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (PMID:16100574) RGD PMID:16100574 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1916289 (PMID:16100574)
Ensembl
RGD
PMID:16100574 GO_REF:0000107 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Klhl25 kelch-like family member 25 involved_in ISO (PMID:27664236) RGD PMID:27664236 NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227
JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir30c1 microRNA 30c-1 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
JBrowse link
G Mir30c2 microRNA 30c-2 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (PMID:16794074) RGD PMID:16794074 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:23932781)
Ensembl
RGD
PMID:23932781 GO_REF:0000107 NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784
JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:17767906)
GO_Central
RGD
PMID:17767906 GO_REF:0000033 NCBI chr 5:145,491,460...145,559,631
Ensembl chr 5:145,491,466...145,540,408
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir204 microRNA 204 involved_in ISO (PMID:29441883) RGD PMID:29441883 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) RGD PMID:3863495 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20042607)
Ensembl
RGD
PMID:20042607 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
positive regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO (PMID:11606482) RGD PMID:11606482 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
(PMID:2307668)
GO_REF:0000107
RGD
Ensembl
PMID:2307668 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 involved_in ISO
IEA
(PMID:18635818)
GO_REF:0000107
RGD
Ensembl
PMID:18635818 GO_REF:0000107 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:10727238) RGD PMID:10727238 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in ISO
IEA
(PMID:23749231)
GO_REF:0000107
RGD
Ensembl
PMID:23749231 GO_REF:0000107 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IMP RGD PMID:16800817 RGD:1624995 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:14677856) RGD PMID:14677856 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:23932781) RGD PMID:23932781 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 involved_in ISO (PMID:23749231) RGD PMID:23749231 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Mid1ip1 MID1 interacting protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20457939)
UniProt
RGD
PMID:20457939 GO_REF:0000024 NCBI chr  X:12,060,993...12,063,318
Ensembl chr  X:12,060,883...12,065,774
JBrowse link
G Mir96 microRNA 96 involved_in
acts_upstream_of
ISO RNAcentral:URS00001CC379_9606 (PMID:23823476)
(PMID:30460077)
RGD PMID:23823476 PMID:30460077 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Mlxipl MLX interacting protein-like involved_in IEA
ISO
GO_REF:0000107
(PMID:15118080)
Ensembl
RGD
PMID:15118080 GO_REF:0000107 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO
IEA
(PMID:17186944)
GO_REF:0000107
RGD
Ensembl
PMID:17186944 GO_REF:0000107 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:17186944)
GO_REF:0000107
RGD
Ensembl
PMID:17186944 GO_REF:0000107 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Rgn regucalcin IDA RGD PMID:16817230 RGD:9590221 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Sirt2 sirtuin 2 involved_in ISO
IEA
(PMID:23932781)
GO_REF:0000107
RGD
Ensembl
PMID:23932781 GO_REF:0000107 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Slc45a3 solute carrier family 45, member 3 involved_in ISO (PMID:22521588) RGD PMID:22521588 NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588
JBrowse link
positive regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IMP RGD PMID:8260938 RGD:2306959 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Avp arginine vasopressin IMP RGD PMID:17254553 RGD:2300349 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:17254553 RGD:2300349 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Cd74 CD74 molecule involved_in ISO
IEA
(PMID:24569872)
GO_REF:0000107
RGD
Ensembl
PMID:24569872 GO_REF:0000107 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Il1b interleukin 1 beta involved_in ISO RNAcentral:URS0000424278_9606 (PMID:29384235) RGD PMID:29384235 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:9786861 RGD:2304243 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:23624557) RGD PMID:23624557 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pla2g4a phospholipase A2 group 4A IMP RGD PMID:16203828 RGD:1642461 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:24287039) RGD PMID:24287039 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
positive regulation of unsaturated fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISO (PMID:18854420) RGD PMID:18854420 NCBI chr  X:151,428,334...151,450,115
Ensembl chr  X:151,428,578...151,450,115
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:18854420)
UniProt
RGD
PMID:18854420 GO_REF:0000024 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
JBrowse link
regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp5 fatty acid binding protein 5 involved_in ISO (PMID:29440395) RGD PMID:29440395 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      regulation of cellular process 12767
        regulation of metabolic process 6743
          regulation of biosynthetic process 5507
            regulation of lipid biosynthetic process 231
              regulation of fatty acid biosynthetic process 57
                negative regulation of fatty acid biosynthetic process + 23
                positive regulation of fatty acid biosynthetic process + 29
                regulation of butyryl-CoA biosynthetic process from acetyl-CoA + 0
                regulation of butyryl-CoA catabolic process to butyrate + 0
                regulation of jasmonic acid biosynthetic process 0
                regulation of methyl-branched fatty acid biosynthetic process + 0
                regulation of unsaturated fatty acid biosynthetic process + 16
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11950
        small molecule metabolic process 1914
          organic acid metabolic process 1044
            oxoacid metabolic process 1031
              carboxylic acid metabolic process 1016
                monocarboxylic acid metabolic process 743
                  fatty acid metabolic process 455
                    regulation of fatty acid metabolic process 119
                      regulation of fatty acid biosynthetic process 57
                        negative regulation of fatty acid biosynthetic process + 23
                        positive regulation of fatty acid biosynthetic process + 29
                        regulation of butyryl-CoA biosynthetic process from acetyl-CoA + 0
                        regulation of butyryl-CoA catabolic process to butyrate + 0
                        regulation of jasmonic acid biosynthetic process 0
                        regulation of methyl-branched fatty acid biosynthetic process + 0
                        regulation of unsaturated fatty acid biosynthetic process + 16
paths to the root