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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Chemical and Drug Induced Liver Injury
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Accession:DOID:9007383 term browser browse the term
Definition:A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Synonyms:exact_synonym: Chemically Induced Liver Toxicity;   Drug Induced Acute Liver Injury;   Drug Induced Liver Disease;   Drug Induced Liver Injury;   Drug-Induced Liver Diseases;   Drug-Induced Liver Injuries;   Toxic Hepatitis;   chemically-induced liver toxicities;   hepatotoxicity;   toxic hepatitides
 narrow_synonym: Drug-induced liver injury due to flucloxacillin
 primary_id: MESH:D056486
 alt_id: RDO:0007742
 xref: EFO:0004228;   EFO:0011052;   NCI:C84427


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Chemical and Drug Induced Liver Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624783:13,831,220...13,904,806
Ensembl chrNW_004624783:13,831,150...13,902,082
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 severity ISO DNA:SNP: :rs2287616(human) RGD PMID:27293027 RGD:14402413 NCBI chrNW_004624787:6,653,849...6,733,058
Ensembl chrNW_004624787:6,650,772...6,733,195
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18466103 NCBI chrNW_004624782:449,217...590,306
Ensembl chrNW_004624782:449,288...591,310
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 susceptibility ISO DNA:polymorphism:promoter:-24C>T(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17241877 PMID:18381794 PMID:18466103 PMID:25196354 RGD:14700812 RGD:14700814 NCBI chrNW_004624737:11,593,701...11,686,790
Ensembl chrNW_004624737:11,593,864...11,688,460
JBrowse link
G Abi1 abl interactor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624796:2,312,005...2,431,284 JBrowse link
G Ace angiotensin I converting enzyme ISO mRNA:increased expression:liver (rat) RGD PMID:25143335 RGD:25671447 NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624755:23,995,256...24,026,581
Ensembl chrNW_004624755:23,995,089...24,024,083
JBrowse link
G Acsl1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624769:15,503,757...15,584,741
Ensembl chrNW_004624769:15,503,757...15,584,777
JBrowse link
G Actb actin beta ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver
CTD
RGD
PMID:22563491 PMID:25231249 RGD:9587759 NCBI chrNW_004624740:28,087,051...28,090,359
Ensembl chrNW_004624740:28,087,736...28,090,512
JBrowse link
G Actn4 actinin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624794:12,042,627...12,113,762
Ensembl chrNW_004624794:12,042,533...12,113,886
JBrowse link
G Actr3 actin related protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624732:31,360,804...31,427,885
Ensembl chrNW_004624732:31,361,147...31,427,811
JBrowse link
G Ada adenosine deaminase ISO protein:increased expression:liver RGD PMID:21161045 RGD:5128859 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24646716 NCBI chrNW_004624737:13,459,274...13,474,686 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:20709802 NCBI chrNW_004624730:69,941,963...69,959,266
Ensembl chrNW_004624730:69,941,001...69,957,012
JBrowse link
G Adipor2 adiponectin receptor 2 severity ISO associated with obesity, LPS;mRNA:decreased expression:liver (rat) RGD PMID:23838384 RGD:8695926 NCBI chrNW_004624735:11,103,082...11,174,277
Ensembl chrNW_004624735:11,103,076...11,174,337
JBrowse link
G Adora2b adenosine A2b receptor ISO CTD Direct Evidence: therapeutic CTD PMID:35292334 NCBI chrNW_004624877:4,421,307...4,447,574
Ensembl chrNW_004624877:4,422,022...4,447,460
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29499335 NCBI chrNW_004624775:18,846,222...18,856,093
Ensembl chrNW_004624775:18,849,118...18,855,577
JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:decreased expression:liver (rat)
CTD
RGD
PMID:21890736 PMID:28959666 PMID:34848246 RGD:401794432 NCBI chrNW_004624739:12,939,183...12,987,574
Ensembl chrNW_004624739:12,942,165...12,987,973
JBrowse link
G Aifm1 apoptosis inducing factor mitochondria associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25743375 NCBI chrNW_004624797:9,346,620...9,384,531
Ensembl chrNW_004624797:9,345,726...9,384,645
JBrowse link
G Ak4 adenylate kinase 4 ISO protein:increased expression:liver (rat) RGD PMID:16538043 RGD:2301096 NCBI chrNW_004624742:29,547,237...29,574,160 JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29763686 PMID:32805337 RGD:27226688 NCBI chrNW_004624906:1,463,201...1,474,001
Ensembl chrNW_004624906:1,462,693...1,474,214
JBrowse link
G Alb albumin treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18779383 PMID:22310181 PMID:27567545 RGD:14694844 NCBI chrNW_004624735:34,105,237...34,123,479
Ensembl chrNW_004624735:34,104,537...34,123,624
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family member L2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624750:3,912,030...4,054,170
Ensembl chrNW_004624750:3,912,002...3,961,963
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member severity
susceptibility
ISO DNA:deletion:exon 3 (mouse)
protein:increased expression:liver
RGD PMID:21138988 PMID:24492981 PMID:30121625 RGD:14975148 RGD:15036810 RGD:7241599 NCBI chrNW_004624747:20,407,190...20,438,605
Ensembl chrNW_004624747:20,403,717...20,438,690
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624826:3,994,188...4,026,437
Ensembl chrNW_004624826:3,994,183...4,026,696
JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16115720 NCBI chrNW_004624758:9,868,223...9,880,205
Ensembl chrNW_004624758:9,868,260...9,880,205
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18779383 NCBI chrNW_004624760:21,047,576...21,064,698
Ensembl chrNW_004624760:21,047,303...21,068,076
JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624781:11,781,893...11,820,440
Ensembl chrNW_004624781:11,781,886...11,821,816
JBrowse link
G Anxa6 annexin A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624733:41,024,503...41,071,390
Ensembl chrNW_004624733:41,024,514...41,071,353
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136
JBrowse link
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Apoh apolipoprotein H ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:plasma:
CTD
RGD
PMID:16099942 PMID:23288050 RGD:10054107 NCBI chrNW_004624870:2,082,050...2,096,220
Ensembl chrNW_004624870:2,081,968...2,099,517
JBrowse link
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22872058 NCBI chrNW_004624753:5,737,720...5,749,313
Ensembl chrNW_004624753:5,737,237...5,752,966
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20935161 NCBI chrNW_004624772:18,949,221...19,016,672
Ensembl chrNW_004624772:18,949,108...19,015,504
JBrowse link
G Atg5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22491424 NCBI chrNW_004624780:15,987,483...16,124,158
Ensembl chrNW_004624780:15,987,397...16,124,151
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624749:17,397,332...17,428,980
Ensembl chrNW_004624749:17,399,111...17,428,893
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624734:33,640,842...33,669,471
Ensembl chrNW_004624734:33,640,839...33,657,745
JBrowse link
G Avp arginine vasopressin ISO DNA:SNP:intron: (rs2282018) RGD PMID:28462386 RGD:408364979 NCBI chrNW_004624741:4,208,305...4,210,097
Ensembl chrNW_004624741:4,208,329...4,210,071
JBrowse link
G Bad BCL2 associated agonist of cell death treatment ISO RGD PMID:25447754 RGD:10053709 NCBI chrNW_004624767:22,025,721...22,037,283
Ensembl chrNW_004624767:22,026,133...22,037,277
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17906064 NCBI chrNW_004624832:5,050,222...5,068,565
Ensembl chrNW_004624832:5,050,222...5,055,506
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624730:62,397,242...62,466,172
Ensembl chrNW_004624730:62,397,245...62,424,924
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30685357 NCBI chrNW_004624734:8,513,601...8,538,838
Ensembl chrNW_004624734:8,513,814...8,539,036
JBrowse link
G Blvrb biliverdin reductase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624925:432,137...452,946
Ensembl chrNW_004624925:432,137...452,903
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 ISO CTD Direct Evidence: therapeutic CTD PMID:36602574 NCBI chrNW_004624766:5,295,120...5,391,645
Ensembl chrNW_004624766:5,317,635...5,391,645
JBrowse link
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624835:3,704,455...3,722,825
Ensembl chrNW_004624835:3,704,664...3,718,129
JBrowse link
G Brd4 bromodomain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624901:2,348,218...2,434,429
Ensembl chrNW_004624901:2,346,734...2,380,852
JBrowse link
G Btd biotinidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15469856 NCBI chrNW_004624821:926,159...948,331
Ensembl chrNW_004624821:926,310...949,065
JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946
JBrowse link
G Ca3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 PMID:25231249 NCBI chrNW_004624744:6,202,151...6,211,662
Ensembl chrNW_004624744:6,199,382...6,212,163
JBrowse link
G Cabp1 calcium binding protein 1 ISO protein:increased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chrNW_004624747:13,027,839...13,050,262
Ensembl chrNW_004624747:13,027,844...13,050,165
JBrowse link
G Cadps2 calcium dependent secretion activator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624783:13,142,036...13,701,430
Ensembl chrNW_004624783:13,142,198...13,700,683
JBrowse link
G Canx calnexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624733:42,588,680...42,616,624 JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624764:22,517,254...22,542,356
Ensembl chrNW_004624764:22,517,315...22,542,351
JBrowse link
G Casp8 caspase 8 treatment ISO RGD PMID:25447754 RGD:10053709 NCBI chrNW_004624899:427,064...450,931
Ensembl chrNW_004624899:424,363...451,087
JBrowse link
G Cast calpastatin ISO RGD PMID:16871587 RGD:5683869 NCBI chrNW_004624743:15,265,930...15,405,904
Ensembl chrNW_004624743:15,346,837...15,403,150
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:liver
CTD
RGD
PMID:20623750 PMID:21138988 PMID:25231249 RGD:7241599 NCBI chrNW_004624767:12,680,940...12,715,468
Ensembl chrNW_004624767:12,680,953...12,715,739
JBrowse link
G Ccdc80 coiled-coil domain containing 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624731:35,891,180...35,928,497
Ensembl chrNW_004624731:35,891,184...35,929,936
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624885:1,575,560...1,592,540
Ensembl chrNW_004624885:1,575,562...1,592,594
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624751:7,615,098...7,628,985
Ensembl chrNW_004624751:7,615,007...7,630,606
JBrowse link
G Cdc25b cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624741:4,871,275...4,892,730
Ensembl chrNW_004624741:4,882,516...4,892,925
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624900:1,701,507...1,765,791
Ensembl chrNW_004624900:1,701,522...1,766,768
JBrowse link
G Cela1 chymotrypsin like elastase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624816:906,103...939,252
Ensembl chrNW_004624816:906,121...939,696
JBrowse link
G Cfap20 cilia and flagella associated protein 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624746:28,071,502...28,085,040
Ensembl chrNW_004624746:28,071,519...28,085,231
JBrowse link
G Cfh complement factor H ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624798:3,332,549...3,414,435 JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20197374 NCBI chrNW_004624775:10,948,075...11,427,898
Ensembl chrNW_004624775:10,949,983...10,951,755
JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624734:1,346,056...1,349,383
Ensembl chrNW_004624734:1,346,510...1,349,383
JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004624758:22,431,331...22,444,185
Ensembl chrNW_004624758:22,426,918...22,444,357
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624763:17,982,646...18,172,742
Ensembl chrNW_004624763:17,982,646...18,172,904
JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16679477 NCBI chrNW_004624899:1,192,078...1,230,528
Ensembl chrNW_004624899:1,192,360...1,230,404
JBrowse link
G Comt catechol-O-methyltransferase ISO protein:decreased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chrNW_004624747:569,127...588,479
Ensembl chrNW_004624747:581,832...588,333
JBrowse link
G Coq9 coenzyme Q9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624746:28,614,589...28,630,774
Ensembl chrNW_004624746:28,615,215...28,630,667
JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624730:26,458,554...26,510,796
Ensembl chrNW_004624730:26,462,550...26,511,078
JBrowse link
G Cpb2 carboxypeptidase B2 ISO mRNA,protein:increased expression,increased activity:liver,plasma RGD PMID:19386599 RGD:7243112 NCBI chrNW_004624748:8,850,128...8,927,986
Ensembl chrNW_004624748:8,849,900...8,928,853
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624765:5,527,029...5,652,343
Ensembl chrNW_004624765:5,528,112...5,651,415
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chrNW_004624767:18,109,011...18,161,378
Ensembl chrNW_004624767:18,109,008...18,161,639
JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:20005281 PMID:33882750 NCBI chrNW_004624795:3,162,999...3,167,248
Ensembl chrNW_004624795:3,163,009...3,166,594
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19679878 NCBI chrNW_004624730:77,876,361...77,887,228
Ensembl chrNW_004624730:77,875,257...77,887,234
JBrowse link
G Ctse cathepsin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624807:5,291,993...5,306,507
Ensembl chrNW_004624807:5,291,736...5,305,104
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11739529 NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:38614205 NCBI chrNW_004624733:11,455,166...11,463,086
Ensembl chrNW_004624733:11,455,047...11,463,176
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624857:3,056,799...3,138,430
Ensembl chrNW_004624857:3,056,781...3,138,396
JBrowse link
G Ddb1 damage specific DNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624926:871,003...893,902
Ensembl chrNW_004624926:871,000...897,777
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004624817:1,386,876...1,418,129
Ensembl chrNW_004624817:1,386,764...1,418,300
JBrowse link
G Dhfr dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648163 NCBI chrNW_004624743:1,446,643...1,462,319
Ensembl chrNW_004624743:1,446,643...1,461,863
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624734:40,994,786...41,006,001
Ensembl chrNW_004624734:40,993,587...41,006,074
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624784:7,181,550...7,216,779
Ensembl chrNW_004624784:7,181,671...7,214,751
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624739:21,187,581...21,193,345
Ensembl chrNW_004624739:21,187,581...21,193,337
JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624754:2,175,204...2,227,405
Ensembl chrNW_004624754:2,172,942...2,227,529
JBrowse link
G Dsc2 desmocollin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624770:1,748,561...1,778,566
Ensembl chrNW_004624770:1,748,276...1,781,117
JBrowse link
G E2f1 E2F transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chrNW_004624842:5,602,432...5,612,951
Ensembl chrNW_004624842:5,602,432...5,612,951
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624753:1,707,116...1,750,708
Ensembl chrNW_004624753:1,708,153...1,740,824
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624737:13,329,052...13,338,358
Ensembl chrNW_004624737:13,328,904...13,338,366
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624773:15,846,347...15,878,312
Ensembl chrNW_004624773:15,846,553...15,878,803
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25411909 NCBI chrNW_004624740:31,223,583...31,306,749
Ensembl chrNW_004624740:31,274,483...31,306,430
JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624754:4,523,616...4,553,994
Ensembl chrNW_004624754:4,523,661...4,549,936
JBrowse link
G Endog endonuclease G ISO protein:decreased expression:mitochondrion: RGD PMID:22509279 RGD:9685364 NCBI chrNW_004624760:6,193,168...6,196,209
Ensembl chrNW_004624760:6,193,173...6,196,374
JBrowse link
G Eng endoglin ISO protein:increased expression:liver (rat) RGD PMID:21146604 RGD:7257529 NCBI chrNW_004624760:7,703,979...7,735,636
Ensembl chrNW_004624760:7,703,820...7,734,457
JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 PMID:25231249 NCBI chrNW_004624818:3,223,384...3,235,128
Ensembl chrNW_004624818:3,223,308...3,238,419
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO protein:increased activity:serum: RGD PMID:17850827 RGD:9685426 NCBI chrNW_004624763:17,677,825...17,775,284
Ensembl chrNW_004624763:17,677,722...17,765,292
JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624835:6,161,930...6,181,016
Ensembl chrNW_004624835:6,162,111...6,168,714
JBrowse link
G Erlec1 endoplasmic reticulum lectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624833:7,964,815...7,992,277
Ensembl chrNW_004624833:7,964,810...7,992,582
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30538632 NCBI chrNW_004624849:1,521,996...1,625,878
Ensembl chrNW_004624849:1,525,235...1,625,893
JBrowse link
G F13a1 coagulation factor XIII A chain ISO RGD PMID:22019897 RGD:11041813 NCBI chrNW_004624756:19,103,064...19,259,632
Ensembl chrNW_004624756:19,103,327...19,259,964
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20974703 NCBI chrNW_004624908:761,067...764,562
Ensembl chrNW_004624908:762,356...766,563
JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22407844 NCBI chrNW_004624742:3,112,827...3,123,424
Ensembl chrNW_004624742:3,112,801...3,124,301
JBrowse link
G Fadd Fas associated via death domain treatment ISO RGD PMID:25447754 PMID:26062544 RGD:10053709 RGD:11341803 NCBI chrNW_004624767:17,050,929...17,059,648
Ensembl chrNW_004624767:17,055,509...17,059,705
JBrowse link
G Fads1 fatty acid desaturase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624926:594,421...607,654
Ensembl chrNW_004624926:598,922...606,611
JBrowse link
G Fads2 fatty acid desaturase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624926:529,456...548,800
Ensembl chrNW_004624926:528,791...548,854
JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:liver (rat) RGD PMID:16831245 RGD:8662853 NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624801:10,910,022...10,926,505
Ensembl chrNW_004624801:10,909,647...10,927,547
JBrowse link
G Fcmr Fc mu receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624807:4,567,240...4,581,406 JBrowse link
G Fga fibrinogen alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20974703 NCBI chrNW_004624858:5,848,817...5,856,448 JBrowse link
G Fgf21 fibroblast growth factor 21 severity ISO mRNA:increased expression:liver (rat) RGD PMID:29883717 RGD:15045603 NCBI chrNW_004624832:5,165,195...5,166,865
Ensembl chrNW_004624832:5,164,856...5,167,370
JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21135413 NCBI chrNW_004624776:10,043,113...10,218,598
Ensembl chrNW_004624776:10,043,258...10,219,104
JBrowse link
G Ftl ferritin light chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624832:5,046,207...5,047,828
Ensembl chrNW_004624832:5,046,208...5,047,828
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 ISO mRNA:decreased expression:liver (mouse) RGD PMID:28189721 RGD:14695531 NCBI chrNW_004624795:1,331,592...1,339,575
Ensembl chrNW_004624795:1,331,601...1,339,580
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment ISO RGD PMID:21864513 RGD:10449168 NCBI chrNW_004624946:989,376...1,001,787
Ensembl chrNW_004624946:986,107...1,001,955
JBrowse link
G Gadd45a growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004624742:27,727,801...27,730,252
Ensembl chrNW_004624742:27,727,660...27,730,316
JBrowse link
G Ganab glucosidase II alpha subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624926:1,147,470...1,160,901
Ensembl chrNW_004624926:1,146,886...1,160,876
JBrowse link
G Gc GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624890:3,274,239...3,318,281
Ensembl chrNW_004624890:3,226,900...3,318,316
JBrowse link
G Gclc glutamate-cysteine ligase catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17573345 PMID:19481141 RGD:10402383 NCBI chrNW_004624850:749,046...793,654
Ensembl chrNW_004624850:749,050...793,959
JBrowse link
G Gclm glutamate-cysteine ligase modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624742:3,713,275...3,746,219
Ensembl chrNW_004624742:3,713,250...3,743,290
JBrowse link
G Gda guanine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624736:836,283...914,616
Ensembl chrNW_004624736:836,286...914,409
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624946:902,831...908,815
Ensembl chrNW_004624946:902,461...909,613
JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO RGD PMID:15968720 PMID:22033404 RGD:9685722 RGD:9685727 NCBI chrNW_004624913:273,126...276,353
Ensembl chrNW_004624913:273,705...275,693
JBrowse link
G Ggh gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21219404 NCBI chrNW_004624744:28,752,785...28,786,293
Ensembl chrNW_004624744:28,752,909...28,785,661
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chrNW_004624747:10,030,034...10,048,554 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:34151639 NCBI chrNW_004624731:5,257,813...5,262,878
Ensembl chrNW_004624731:5,257,830...5,262,473
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33483742 NCBI chrNW_004624841:133,267...171,324 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624737:11,114,818...11,153,209
Ensembl chrNW_004624737:11,115,066...11,153,211
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624816:2,203,731...2,211,006
Ensembl chrNW_004624816:2,203,731...2,210,509
JBrowse link
G Gpt glutamic--pyruvic transaminase treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression, activity:serum:
RGD
CTD
PMID:145039 PMID:19085960 PMID:19481104 PMID:21772750 PMID:27293452 More... RGD:14975162 RGD:14975166 RGD:14975168 RGD:14975249 NCBI chrNW_004624735:12,355,476...12,359,910
Ensembl chrNW_004624735:12,355,476...12,360,028
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 ISO protein:increased expression, activity:serum: RGD PMID:19085960 RGD:14975249 NCBI chrNW_004624914:460,240...501,087
Ensembl chrNW_004624914:459,701...501,765
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624755:24,741,985...24,789,972
Ensembl chrNW_004624755:24,742,073...24,830,314
JBrowse link
G Gsn gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624760:13,943,680...14,004,660
Ensembl chrNW_004624760:13,943,888...13,969,905
JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:23554813 PMID:24154663 PMID:25226513 PMID:28069987 RGD:10401878 RGD:7257532 NCBI chrNW_004624780:13,440,269...13,497,435
Ensembl chrNW_004624780:13,440,235...13,496,535
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624850:201,119...217,302
Ensembl chrNW_004624850:201,592...216,680
JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO CTD Direct Evidence: therapeutic CTD PMID:25743375 NCBI chrNW_004624772:5,495,452...5,498,714
Ensembl chrNW_004624772:5,495,452...5,498,652
JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624831:3,342,539...3,351,766
Ensembl chrNW_004624831:3,342,584...3,352,467
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624822:5,078,925...5,189,253
Ensembl chrNW_004624822:5,079,634...5,145,503
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624738:8,338,250...8,384,701
Ensembl chrNW_004624738:8,338,250...8,384,704
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO mRNA:increased expression:hepatocyte RGD PMID:24373749 RGD:11041724 NCBI chrNW_004624794:8,257,760...8,259,243
Ensembl chrNW_004624794:8,257,760...8,259,264
JBrowse link
G Hao2 hydroxyacid oxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624772:14,981,777...15,022,699
Ensembl chrNW_004624772:14,981,666...15,023,173
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004624733:32,284,793...32,310,980 JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:19783637 PMID:29091898 RGD:15090820 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:18227147 PMID:22688006 PMID:22886620 PMID:29091898 RGD:10762620 RGD:15090820 NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 PMID:22872058 NCBI chrNW_004624747:22,209,191...22,217,665
Ensembl chrNW_004624747:22,209,009...22,217,841
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624797:14,148,580...14,184,471 JBrowse link
G Hpx hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624817:7,947,554...7,957,553
Ensembl chrNW_004624817:7,947,639...7,957,462
JBrowse link
G Hrh2 histamine receptor H2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22926047 NCBI chrNW_004624733:14,261,799...14,308,320
Ensembl chrNW_004624733:14,260,720...14,308,217
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624760:9,986,529...9,991,261
Ensembl chrNW_004624760:9,986,656...9,995,252
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO protein:altered localization:liver (rat) RGD PMID:12376827 RGD:10059389 NCBI chrNW_004624880:2,070,410...2,075,069
Ensembl chrNW_004624880:2,070,523...2,079,421
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:29091898 RGD:15090820 NCBI chrNW_004624828:2,432,584...2,451,997
Ensembl chrNW_004624828:2,432,550...2,453,071
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO RGD PMID:31121248 RGD:14985250 NCBI chrNW_004624768:17,094,649...17,111,333
Ensembl chrNW_004624768:17,094,655...17,111,397
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289347 NCBI chrNW_004624780:3,620,899...3,668,351
Ensembl chrNW_004624780:3,621,623...3,668,177
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12153990 PMID:21245496 PMID:30013034 RGD:14975100 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23639586 PMID:25226513 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300
JBrowse link
G Il11 interleukin 11 ISO CTD Direct Evidence: therapeutic CTD PMID:11421492 NCBI chrNW_004624832:1,932,959...1,936,937
Ensembl chrNW_004624832:1,933,179...1,935,971
JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: therapeutic CTD PMID:36520315 NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589
JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19633216 PMID:24949944 NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136
JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19164858 NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: therapeutic CTD PMID:8218930 NCBI chrNW_004624749:12,795,967...12,805,658
Ensembl chrNW_004624749:12,795,946...12,805,154
JBrowse link
G Il1b interleukin 1 beta treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:19164858 PMID:23102243 PMID:28138970 PMID:29091898 PMID:29278859 More... RGD:13793380 RGD:14975281 RGD:15036799 RGD:15090820 RGD:7204421 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004624749:6,549,112...6,586,409
Ensembl chrNW_004624749:6,511,584...6,586,511
JBrowse link
G Il22 interleukin 22 ISO CTD Direct Evidence: therapeutic CTD PMID:15122762 PMID:16212920 PMID:23375450 NCBI chrNW_004624802:46,585...51,095
Ensembl chrNW_004624802:46,585...51,095
JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21094227 PMID:21735453 PMID:22107450 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Il6 interleukin 6 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:7532385 PMID:15763341 PMID:29091898 RGD:15090820 NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
JBrowse link
G Immt inner membrane mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624749:17,060,809...17,103,919
Ensembl chrNW_004624749:17,060,790...17,103,919
JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624946:613,392...618,459
Ensembl chrNW_004624946:613,890...618,445
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624773:14,856,803...15,193,173
Ensembl chrNW_004624773:14,856,804...15,193,168
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chrNW_004624908:1,572,628...1,574,205
Ensembl chrNW_004624908:1,573,174...1,574,113
JBrowse link
G Keap1 kelch like ECH associated protein 1 ISO RGD PMID:18417483 RGD:6893370 NCBI chrNW_004624828:2,580,812...2,595,023
Ensembl chrNW_004624828:2,580,861...2,595,275
JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: therapeutic CTD PMID:12594235 NCBI chrNW_004624837:7,456,116...7,541,764
Ensembl chrNW_004624837:7,456,120...7,541,730
JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20362651 PMID:30685357 NCBI chrNW_004624730:70,022,449...70,065,115 JBrowse link
G Krt18 keratin 18 ISO mRNA, protein:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17340120 PMID:19783637 PMID:33483742 PMID:38521541 RGD:18337498 NCBI chrNW_004624904:1,011,675...1,015,319
Ensembl chrNW_004624904:1,011,755...1,015,416
JBrowse link
G Krt8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624904:970,136...978,211 JBrowse link
G Lap3 leucine aminopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624755:14,241,178...14,266,337
Ensembl chrNW_004624755:14,241,178...14,266,280
JBrowse link
G Lbp lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346
JBrowse link
G Lcat lecithin-cholesterol acyltransferase ISO mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chrNW_004624746:18,438,308...18,441,650
Ensembl chrNW_004624746:18,437,429...18,441,806
JBrowse link
G Ldlr low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:36108984 NCBI chrNW_004624828:2,999,122...3,021,893
Ensembl chrNW_004624828:2,999,169...3,021,987
JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22461450 NCBI chrNW_004624731:14,300,138...14,307,843
Ensembl chrNW_004624731:14,298,201...14,304,637
JBrowse link
G Lipc lipase C, hepatic type ISO mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chrNW_004624781:13,342,469...13,468,120
Ensembl chrNW_004624781:13,342,357...13,455,055
JBrowse link
G LOC101700851 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO mRNA, protein:decreased expression:kidney (mouse) RGD PMID:26476181 RGD:25671412 NCBI chrNW_004624802:10,176,865...10,181,725
Ensembl chrNW_004624802:10,176,919...10,181,657
JBrowse link
G LOC101701066 cytochrome P450 1B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chrNW_004624738:19,639,215...19,647,807
Ensembl chrNW_004624738:19,638,456...19,647,497
JBrowse link
G LOC101701891 histone H2AX treatment ISO RGD PMID:23265463 RGD:8693741 NCBI chrNW_004624784:14,475,813...14,477,269
Ensembl chrNW_004624784:14,476,730...14,477,161
JBrowse link
G LOC101703821 HLA class II histocompatibility antigen, DQ beta 1 chain susceptibility ISO DNA:polymorphism, haplotype
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :HLA-DQB1*05(human)
RGD
CTD
PMID:21570397 PMID:25250564 PMID:26959717 RGD:11573514 RGD:36174016 NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713
JBrowse link
G LOC101707509 cytochrome P450 1A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chrNW_004627988:7...1,323 JBrowse link
G LOC101715424 tubulin alpha-1B chain-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624816:3,001,252...3,006,166 JBrowse link
G LOC101719398 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624730:10,078,165...10,109,349 JBrowse link
G LOC101722366 cytochrome P450 2E1 treatment ISO CTD Direct Evidence: marker/mechanism
associated with Endotoxemia
DNA:hypermethylation:promoter
CTD
RGD
PMID:12668988 PMID:16770646 PMID:21741958 PMID:25681370 PMID:27324775 More... RGD:14700872 RGD:14700873 RGD:14700878 RGD:14700879 RGD:14700901 NCBI chrNW_004624737:12,335,733...12,345,278
Ensembl chrNW_004624737:12,335,681...12,345,514
JBrowse link
G Lpl lipoprotein lipase treatment ISO RGD PMID:27071702 RGD:13794380 NCBI chrNW_004624758:15,652,553...15,680,107
Ensembl chrNW_004624758:15,651,992...15,680,762
JBrowse link
G Lrat lecithin retinol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624853:2,936,426...2,941,993
Ensembl chrNW_004624853:2,936,109...2,945,101
JBrowse link
G Ltb4r leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28487374 NCBI chrNW_004624820:8,187,496...8,196,381
Ensembl chrNW_004624820:8,187,496...8,189,562
JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16141546 NCBI chrNW_004624730:74,636,554...74,656,817
Ensembl chrNW_004624730:74,636,522...74,656,886
JBrowse link
G Map1lc3b microtubule associated protein 1 light chain 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624746:3,084,418...3,094,250
Ensembl chrNW_004624746:3,084,392...3,094,250
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18700144 NCBI chrNW_004624886:970,415...1,189,595
Ensembl chrNW_004624886:969,623...1,190,709
JBrowse link
G Mat1a methionine adenosyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624841:6,843,725...6,864,700
Ensembl chrNW_004624841:6,843,741...6,862,683
JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624730:60,749,678...60,803,091
Ensembl chrNW_004624730:60,749,896...60,803,235
JBrowse link
G Mdh1 malate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624762:9,884,521...9,900,593
Ensembl chrNW_004624762:9,881,950...9,901,372
JBrowse link
G Me1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624799:11,166,398...11,382,662 JBrowse link
G Med1 mediator complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16109766 NCBI chrNW_004624795:3,572,025...3,605,675
Ensembl chrNW_004624795:3,572,266...3,607,126
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15763341 NCBI chrNW_004624757:1,450,680...1,479,160
Ensembl chrNW_004624757:1,448,698...1,479,255
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chrNW_004624790:8,584,399...8,591,763
Ensembl chrNW_004624790:8,583,457...8,591,713
JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624730:3,612,467...3,617,257
Ensembl chrNW_004624730:3,610,241...3,617,530
JBrowse link
G Mst1r macrophage stimulating 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22575169 NCBI chrNW_004624730:3,802,452...3,818,593
Ensembl chrNW_004624730:3,800,749...3,822,389
JBrowse link
G Mthfr methylenetetrahydrofolate reductase treatment ISO CTD Direct Evidence: marker/mechanism
associated with precursor lymphoblastic lymphoma/leukemia; DNA:SNP: :677C>T(human)
CTD
RGD
PMID:18551038 PMID:19648163 PMID:30545275 RGD:14696733 NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168
JBrowse link
G Mtpn myotrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624765:16,182,691...16,218,634
Ensembl chrNW_004624765:16,181,809...16,218,720
JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:17615358 RGD:150521532 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624767:1,238,953...1,243,945
Ensembl chrNW_004624767:1,237,261...1,244,031
JBrowse link
G Nfatc4 nuclear factor of activated T cells 4 ISO CTD Direct Evidence: therapeutic CTD PMID:34192554 NCBI chrNW_004624820:8,136,231...8,145,395
Ensembl chrNW_004624820:8,136,156...8,146,312
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO CTD Direct Evidence: therapeutic
induced by methotrexate (CHEBI:44185), treated by ferulic acid (CHEBI:17620)
RGD
CTD
PMID:18417483 PMID:22491424 PMID:22627062 PMID:24813929 PMID:26958860 More... RGD:15090820 RGD:21201280 RGD:21201283 RGD:21201305 RGD:21201308 RGD:6893370 NCBI chrNW_004624787:14,355,330...14,381,353
Ensembl chrNW_004624787:14,355,791...14,381,251
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 treatment
susceptibility
ISO associated with tuberculosis ;DNA:SNPs,haplotypes: 3'utr,5'utr: (rs78872571,rs4647992) (human) RGD PMID:29091898 PMID:31490979 RGD:15090820 RGD:40902984 NCBI chrNW_004624830:5,334,273...5,430,887
Ensembl chrNW_004624830:5,333,616...5,408,723
JBrowse link
G Nfxl1 nuclear transcription factor, X-box binding like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624761:19,029,537...19,084,156
Ensembl chrNW_004624761:19,029,434...19,084,307
JBrowse link
G Notch1 notch receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:30394310 NCBI chrNW_004624760:1,636,331...1,676,398
Ensembl chrNW_004624760:1,634,702...1,676,531
JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624845:669,880...829,471
Ensembl chrNW_004624845:669,902...827,834
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:28472605 PMID:28522909 PMID:29091898 RGD:13439737 RGD:13439739 RGD:15090820 NCBI chrNW_004624746:16,684,620...16,698,194
Ensembl chrNW_004624746:16,684,407...16,697,479
JBrowse link
G Nr0b2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29943110 NCBI chrNW_004624764:10,896,728...10,899,898
Ensembl chrNW_004624764:10,892,481...10,899,215
JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 treatment ISO RGD PMID:24497272 RGD:10448995 NCBI chrNW_004624795:3,102,424...3,109,497
Ensembl chrNW_004624795:3,102,439...3,109,497
JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO CTD Direct Evidence: therapeutic CTD PMID:17256725 NCBI chrNW_004624767:1,459,601...1,473,224
Ensembl chrNW_004624767:1,459,601...1,467,795
JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 treatment
severity
ISO mRNA:decreased expression:liver (rat)
protein:decreased expression:liver (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12875239 PMID:20573685 PMID:22711662 PMID:28827769 PMID:29091898 More... RGD:14701035 RGD:14701036 RGD:15042870 RGD:15045609 RGD:15090820 NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834
JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 susceptibility ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with tuberculosis ;DNA:SNP,haplotypes:promoter: (rs3814055) (human)
CTD
RGD
PMID:19797606 PMID:28058446 PMID:31490979 RGD:40902984 NCBI chrNW_004624731:28,371,707...28,405,327
Ensembl chrNW_004624731:28,371,707...28,381,357
JBrowse link
G Nr1i3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14742670 PMID:25656644 PMID:28058446 NCBI chrNW_004624794:141,316...158,059 JBrowse link
G Nr2f2 nuclear receptor subfamily 2 group F member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624768:7,713,771...7,728,102
Ensembl chrNW_004624768:7,701,674...7,728,408
JBrowse link
G Nr5a2 nuclear receptor subfamily 5 group A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29515023 NCBI chrNW_004624798:356,953...494,877 JBrowse link
G Nrep neuronal regeneration related protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624743:29,529,356...29,557,620
Ensembl chrNW_004624743:29,529,356...29,557,414
JBrowse link
G Ntn1 netrin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:35292334 NCBI chrNW_004624786:11,508,643...11,707,060
Ensembl chrNW_004624786:11,526,050...11,703,258
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO CTD Direct Evidence: therapeutic CTD PMID:33812996 NCBI chrNW_004624798:12,132,570...12,154,252
Ensembl chrNW_004624798:12,130,569...12,154,314
JBrowse link
G Ociad1 OCIA domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624761:18,144,270...18,171,205 JBrowse link
G Ogdh oxoglutarate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624740:7,481,719...7,549,809
Ensembl chrNW_004624740:7,482,314...7,549,417
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624801:10,700,301...10,712,889
Ensembl chrNW_004624801:10,699,161...10,712,896
JBrowse link
G Pah phenylalanine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624750:5,527,720...5,598,173
Ensembl chrNW_004624750:5,527,638...5,601,964
JBrowse link
G Pan2 poly(A) specific ribonuclease subunit PAN2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624802:11,668,977...11,686,840
Ensembl chrNW_004624802:11,669,908...11,686,122
JBrowse link
G Panx1 pannexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29246445 NCBI chrNW_004624735:38,766,973...38,823,284
Ensembl chrNW_004624735:38,766,981...38,819,092
JBrowse link
G Park7 Parkinsonism associated deglycase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624818:3,900,917...3,915,457
Ensembl chrNW_004624818:3,900,917...3,911,042
JBrowse link
G Pc pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624767:19,481,158...19,601,036
Ensembl chrNW_004624767:19,480,522...19,614,051
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624740:16,476,004...16,480,818
Ensembl chrNW_004624740:16,475,058...16,480,807
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624730:61,417,030...61,466,028
Ensembl chrNW_004624730:61,418,013...61,466,016
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21182459 PMID:31809757 NCBI chrNW_004624813:2,258,279...2,270,540
Ensembl chrNW_004624813:2,258,279...2,270,824
JBrowse link
G Pdlim5 PDZ and LIM domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624757:22,332,479...22,597,312
Ensembl chrNW_004624757:22,332,505...22,597,586
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624768:16,751,366...16,759,829
Ensembl chrNW_004624768:16,751,366...16,760,326
JBrowse link
G Pgm1 phosphoglucomutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624742:30,543,161...30,592,117
Ensembl chrNW_004624742:30,542,448...30,592,162
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chrNW_004624780:1,014,429...1,063,636
Ensembl chrNW_004624780:1,028,085...1,063,649
JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chrNW_004624855:2,362,793...2,401,519
Ensembl chrNW_004624855:2,360,229...2,402,079
JBrowse link
G Pls3 plastin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624940:120,073...216,522
Ensembl chrNW_004624940:120,073...216,622
JBrowse link
G Pnp purine nucleoside phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624825:4,688,662...4,699,912
Ensembl chrNW_004624825:4,690,831...4,700,717
JBrowse link
G Pnrc1 proline rich nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624799:5,097,175...5,100,692
Ensembl chrNW_004624799:5,097,809...5,100,507
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit susceptibility
no_association
ISO DNA:missense mutation:cds:p.W748S, p.E1143G (2243G>C, 3428A>G) (human)
DNA:missense mutations:cds:p.Q1236H, p.E1143G (33708G>T, 3428A>G) (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18208989 PMID:20138553 PMID:25065347 PMID:30255931 RGD:15039297 RGD:15039302 NCBI chrNW_004624768:16,493,123...16,509,747
Ensembl chrNW_004624768:16,491,555...16,509,900
JBrowse link
G Polr2g RNA polymerase II subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624926:1,228,590...1,230,943
Ensembl chrNW_004624926:1,228,602...1,230,943
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624813:1,953,796...1,979,846
Ensembl chrNW_004624813:1,949,614...1,979,882
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO LPS-induced acute liver damage
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:21262334 PMID:24385052 PMID:38181850 RGD:5509941 NCBI chrNW_004624752:3,646,499...3,702,553
Ensembl chrNW_004624752:3,650,922...3,701,672
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO mRNA, protein:decreased expression:liver RGD PMID:26599535 RGD:11554658 NCBI chrNW_004624956:84,673...207,176
Ensembl chrNW_004624956:83,842...149,481
JBrowse link
G Pptc7 protein phosphatase targeting COQ7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624747:21,320,525...21,358,830
Ensembl chrNW_004624747:21,320,617...21,358,904
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 treatment ISO RGD PMID:29091898 RGD:15090820 NCBI chrNW_004624759:14,143,439...14,174,971
Ensembl chrNW_004624759:14,142,956...14,171,718
JBrowse link
G Prkcd protein kinase C delta ISO CTD Direct Evidence: therapeutic CTD PMID:30393195 NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21224054 NCBI chrNW_004624735:7,534,483...7,702,079
Ensembl chrNW_004624735:7,534,506...7,700,305
JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO CTD Direct Evidence: therapeutic CTD PMID:21182459 NCBI chrNW_004624796:5,548,982...5,550,563
Ensembl chrNW_004624796:5,549,184...5,550,439
JBrowse link
G Ptges2 prostaglandin E synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31444509 NCBI chrNW_004624760:7,501,902...7,506,221
Ensembl chrNW_004624760:7,501,939...7,507,093
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:11743745 PMID:29091898 RGD:15090820 NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728
JBrowse link
G Pum1 pumilio RNA binding family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624764:14,361,376...14,486,460
Ensembl chrNW_004624764:14,361,012...14,486,542
JBrowse link
G Pygl glycogen phosphorylase L ISO protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:25231249 PMID:25336395 RGD:21079733 NCBI chrNW_004624731:17,990,877...18,028,351
Ensembl chrNW_004624731:17,990,977...18,028,186
JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624743:6,750,476...6,882,556
Ensembl chrNW_004624743:6,788,108...6,882,223
JBrowse link
G Rbp1 retinol binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624730:16,091,863...16,119,591
Ensembl chrNW_004624730:16,091,863...16,119,591
JBrowse link
G Rdh13 retinol dehydrogenase 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27865848 NCBI chrNW_004624832:2,141,906...2,159,009
Ensembl chrNW_004624832:2,141,902...2,159,009
JBrowse link
G Reep5 receptor accessory protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624743:30,690,339...30,729,229
Ensembl chrNW_004624743:30,690,350...30,729,785
JBrowse link
G Rgn regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624887:3,881,624...3,900,144
Ensembl chrNW_004624887:3,883,213...3,899,277
JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 ISO protein:increased expression:liver (mouse)
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:26769846 PMID:28205631 RGD:127229945 NCBI chrNW_004624820:8,165,546...8,169,172 JBrowse link
G S100a11 S100 calcium binding protein A11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624772:19,563,871...19,568,413
Ensembl chrNW_004624772:19,563,889...19,568,766
JBrowse link
G Scarb1 scavenger receptor class B member 1 ISO mRNA:increased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chrNW_004624747:23,970,782...24,010,683
Ensembl chrNW_004624747:23,973,648...24,010,820
JBrowse link
G Selenbp1 selenium binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004624772:18,496,479...18,505,706
Ensembl chrNW_004624772:18,496,495...18,505,706
JBrowse link
G Sema3a semaphorin 3A ISO CTD Direct Evidence: therapeutic CTD PMID:33290778 NCBI chrNW_004624739:32,104,014...32,426,980
Ensembl chrNW_004624739:32,105,824...32,309,271
JBrowse link
G Sema4a semaphorin 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:33290778 NCBI chrNW_004624885:1,470,666...1,493,634
Ensembl chrNW_004624885:1,470,525...1,495,369
JBrowse link
G Senp2 SUMO specific peptidase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29535048 NCBI chrNW_004624730:71,068,112...71,100,121
Ensembl chrNW_004624730:71,068,112...71,100,225
JBrowse link
G Serpina6 serpin family A member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624734:10,638,031...10,650,297
Ensembl chrNW_004624734:10,637,515...10,651,033
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO associated with precursor lymphoblastic lymphoma/leukemia;DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:23183238 RGD:14696750 NCBI chrNW_004624740:16,128,145...16,136,696
Ensembl chrNW_004624740:16,128,059...16,137,337
JBrowse link
G Serping1 serpin family G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624864:3,091,397...3,103,084
Ensembl chrNW_004624864:3,091,083...3,103,090
JBrowse link
G Sesn2 sestrin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:28209544 NCBI chrNW_004624764:12,087,901...12,135,145
Ensembl chrNW_004624764:12,087,858...12,120,914
JBrowse link
G Sgf29 SAGA complex associated factor 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624782:13,054,643...13,076,640
Ensembl chrNW_004624782:13,054,343...13,072,515
JBrowse link
G Shc1 SHC adaptor protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 PMID:32659284 NCBI chrNW_004624885:2,511,039...2,520,883
Ensembl chrNW_004624885:2,511,240...2,521,155
JBrowse link
G Slc10a1 solute carrier family 10 member 1 ISO mRNA:decreased expression:liver (rat) RGD PMID:28827769 RGD:15045609 NCBI chrNW_004624734:31,287,539...31,307,339
Ensembl chrNW_004624734:31,287,394...31,311,357
JBrowse link
G Slc10a7 solute carrier family 10 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624853:5,110,729...5,365,312
Ensembl chrNW_004624853:5,113,153...5,365,339
JBrowse link
G Slc13a4 solute carrier family 13 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624765:15,960,269...16,001,700
Ensembl chrNW_004624765:15,963,047...16,000,929
JBrowse link
G Slc22a8 solute carrier family 22 member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624926:1,373,804...1,390,248
Ensembl chrNW_004624926:1,374,103...1,388,586
JBrowse link
G Slc25a29 solute carrier family 25 member 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624734:3,830,624...3,839,970
Ensembl chrNW_004624734:3,830,743...3,839,098
JBrowse link
G Slc7a5 solute carrier family 7 member 5 treatment ISO RGD PMID:9200186 RGD:151357001 NCBI chrNW_004624746:1,325,368...1,349,616 JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004624790:9,235,830...9,238,562
Ensembl chrNW_004624790:9,235,650...9,239,231
JBrowse link
G Snx18 sorting nexin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004624759:4,851,014...4,879,365
Ensembl chrNW_004624759:4,850,555...4,879,478
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 PMID:27349771 NCBI chrNW_004624745:20,032,003...20,037,958
Ensembl chrNW_004624745:20,032,011...20,037,958
JBrowse link
G Sod2 superoxide dismutase 2 susceptibility
severity
treatment
ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:p.Val16Ala(human)
associated with acute lymphoblastic leukemia;DNA:SNP: :(rs4880)(human)
RGD
CTD
PMID:19332662 PMID:19647030 PMID:20578157 PMID:25226513 PMID:27019981 RGD:11060605 RGD:26923957 RGD:26923959 RGD:26923961 NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367
JBrowse link
G Sod3 superoxide dismutase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11529661 NCBI chrNW_004624755:7,535,044...7,541,298
Ensembl chrNW_004624755:7,535,044...7,541,221
JBrowse link
G Sord sorbitol dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12763371 NCBI chrNW_004624731:14,159,439...14,185,960
Ensembl chrNW_004624731:14,156,522...14,185,989
JBrowse link
G Sorl1 sortilin related receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624880:3,579,783...3,749,958
Ensembl chrNW_004624880:3,583,838...3,749,930
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004624872:4,505,796...4,513,247
Ensembl chrNW_004624872:4,505,522...4,513,742
JBrowse link
G Srp72 signal recognition particle 72 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624761:12,917,855...12,949,423
Ensembl chrNW_004624761:12,917,855...12,949,457
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: therapeutic CTD PMID:38460807 NCBI chrNW_004624795:1,648,235...1,680,788
Ensembl chrNW_004624795:1,648,080...1,681,200
JBrowse link
G Stat4 signal transducer and activator of transcription 4 severity ISO protein:increased phosphorylation:liver, inflammatory cell (mouse)
mRNA:increased expression:liver, macrophage (mouse)
RGD PMID:23876342 PMID:24731448 RGD:25671417 RGD:25671422 NCBI chrNW_004624854:4,975,724...5,056,940
Ensembl chrNW_004624854:4,976,507...5,057,391
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:36520315 NCBI chrNW_004624743:32,277,197...32,283,346
Ensembl chrNW_004624743:32,273,385...32,283,235
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27052460 NCBI chrNW_004624832:5,268,000...5,290,888
Ensembl chrNW_004624832:5,267,900...5,290,991
JBrowse link
G Suox sulfite oxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624802:12,049,787...12,054,810
Ensembl chrNW_004624802:12,047,270...12,054,523
JBrowse link
G Tagln2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624794:1,331,075...1,338,445 JBrowse link
G Taldo1 transaldolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chrNW_004624766:21,758,821...21,766,052
Ensembl chrNW_004624766:21,758,821...21,766,027
JBrowse link
G Tbxa2r thromboxane A2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22206755 NCBI chrNW_004624828:6,291,010...6,312,438
Ensembl chrNW_004624828:6,291,167...6,309,482
JBrowse link
G Tctn1 tectonic family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004624747:21,259,515...21,300,180
Ensembl chrNW_004624747:21,265,197...21,300,149
JBrowse link
G Tgfb1 transforming growth factor beta 1 treatment ISO RGD PMID:27516150 RGD:14995464 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28560358 NCBI chrNW_004624825:1,773,158...1,899,120
Ensembl chrNW_004624825:1,839,178...1,899,156
JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35357534 NCBI chrNW_004624804:6,849,660...6,866,164
Ensembl chrNW_004624804:6,849,670...6,867,684
JBrowse link
G Thpo thrombopoietin ISO CTD Direct Evidence: therapeutic CTD PMID:33122006 NCBI chrNW_004624730:72,210,880...72,218,615
Ensembl chrNW_004624730:72,212,423...72,219,485
JBrowse link
G Tlr4 toll like receptor 4 disease_progression ISO RGD PMID:17504260 RGD:14697733 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
JBrowse link
G Tlr5 toll like receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30508503 NCBI chrNW_004624835:5,495,723...5,503,462
Ensembl chrNW_004624835:5,500,461...5,503,034
JBrowse link
G Tmem117 transmembrane protein 117 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624816:8,150,836...8,739,599
Ensembl chrNW_004624816:8,151,171...8,730,823
JBrowse link
G Tmem164 transmembrane protein 164 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624803:5,744,576...5,914,749
Ensembl chrNW_004624803:5,744,703...5,914,327
JBrowse link
G Tmem38b transmembrane protein 38B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624758:5,664,287...5,720,061
Ensembl chrNW_004624758:5,662,661...5,719,865
JBrowse link
G Tnf tumor necrosis factor severity
treatment
ISO protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:7532385 PMID:9309314 PMID:9696492 PMID:10801287 PMID:10801288 More... RGD:10450531 RGD:14696804 RGD:14975281 RGD:14995429 RGD:14995432 RGD:14995435 RGD:14995437 RGD:14995485 RGD:15036799 RGD:15090820 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
JBrowse link
G Trpm2 transient receptor potential cation channel subfamily M member 2 ISO RGD PMID:24569808 RGD:9999438 NCBI chrNW_004624745:29,757,267...29,809,607
Ensembl chrNW_004624745:29,757,106...29,806,795
JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004624770:1,255,401...1,262,019
Ensembl chrNW_004624770:1,251,716...1,262,213
JBrowse link
G Tubb4b tubulin beta 4B class IVb ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624760:715,013...717,462
Ensembl chrNW_004624760:712,987...717,951
JBrowse link
G Uba5 ubiquitin like modifier activating enzyme 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004624730:8,791,691...8,819,957
Ensembl chrNW_004624730:8,792,854...8,867,707
JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624767:18,859,990...18,869,083
Ensembl chrNW_004624767:18,860,017...18,868,581
JBrowse link
G Usp5 ubiquitin specific peptidase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624860:3,519,106...3,532,690
Ensembl chrNW_004624860:3,519,113...3,532,687
JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:17784864 PMID:25231249 RGD:15003197 NCBI chrNW_004624754:15,929,414...15,943,637 JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624796:10,624,672...10,632,300
Ensembl chrNW_004624796:10,623,929...10,632,600
JBrowse link
G Vwf von Willebrand factor ISO protein:increased expression:liver:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:7531171 PMID:28527913 RGD:11079232 NCBI chrNW_004624860:2,843,268...2,973,888
Ensembl chrNW_004624860:2,858,088...2,973,052
JBrowse link
G Wasl WASP like actin nucleation promoting factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624783:12,239,467...12,322,403
Ensembl chrNW_004624783:12,254,715...12,323,232
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:haploinsufficiency: : (mouse) RGD PMID:21737425 RGD:15036796 NCBI chrNW_004624907:1,087,611...1,113,275
Ensembl chrNW_004624907:1,087,611...1,113,266
JBrowse link
G Xylb xylulokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004624731:2,616,924...2,658,675
Ensembl chrNW_004624731:2,619,334...2,658,967
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004624731:34,544,476...34,561,284
Ensembl chrNW_004624731:34,544,250...34,560,790
JBrowse link
drug-induced hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 no_association
susceptibility
ISO DNA:SNPs:multiple:
DNA:polymorphisms,haplotype:promoter:g.-1774delG,g.-1549G>A(human)
RGD PMID:17502832 PMID:22178260 RGD:14700816 RGD:14700817 NCBI chrNW_004624737:11,593,701...11,686,790
Ensembl chrNW_004624737:11,593,864...11,688,460
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:16140414 RGD:2316848 NCBI chrNW_004624951:681,559...711,476
Ensembl chrNW_004624951:682,178...711,474
JBrowse link
G LOC101722366 cytochrome P450 2E1 ISO DNA:hypermethylation:promoter RGD PMID:23619520 RGD:14700910 NCBI chrNW_004624737:12,335,733...12,345,278
Ensembl chrNW_004624737:12,335,681...12,345,514
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 ISO protein:increased expression:liver (mouse) RGD PMID:12201952 RGD:10054288 NCBI chrNW_004624758:518,070...668,915
Ensembl chrNW_004624758:519,249...669,471
JBrowse link
Halothane Hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase treatment ISO RGD PMID:28921207 RGD:14975164 NCBI chrNW_004624735:12,355,476...12,359,910
Ensembl chrNW_004624735:12,355,476...12,360,028
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14208
    Chemically-Induced Disorders 1119
      Poisoning 590
        Chemical and Drug Induced Liver Injury 328
          Halothane Hepatitis 1
          drug-induced hepatitis 4
Path 2
Term Annotations click to browse term
  disease 14208
    disease of anatomical entity 13924
      gastrointestinal system disease 6043
        hepatobiliary disease 2661
          liver disease 2563
            Liver Injury 401
              Chemical and Drug Induced Liver Injury 328
                Halothane Hepatitis 1
                drug-induced hepatitis 4
paths to the root