Uba5 (ubiquitin like modifier activating enzyme 5) - Rat Genome Database

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Gene: Uba5 (ubiquitin like modifier activating enzyme 5) Heterocephalus glaber
Analyze
Symbol: Uba5
Name: ubiquitin like modifier activating enzyme 5
RGD ID: 18925987
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); zinc ion binding (ortholog); INVOLVED IN neuromuscular process (ortholog); protein ufmylation (ortholog); regulation of intracellular estrogen receptor signaling pathway (ortholog); ASSOCIATED WITH alkaptonuria (ortholog); autosomal recessive spinocerebellar ataxia 24 (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ubiquitin-like modifier-activating enzyme 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247308,792,854 - 8,867,707 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247308,791,691 - 8,819,957 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Uba5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247308,792,854 - 8,867,707 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247308,791,691 - 8,819,957 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
UBA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383132,654,430 - 132,679,794 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3132,654,446 - 132,679,794 (+)EnsemblGRCh38hg38GRCh38
GRCh373132,373,274 - 132,398,638 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363133,861,836 - 133,879,312 (+)NCBINCBI36Build 36hg18NCBI36
Celera3130,798,783 - 130,822,433 (+)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3129,753,022 - 129,776,586 (+)NCBIHuRef
CHM1_13132,336,305 - 132,359,955 (+)NCBICHM1_1
T2T-CHM13v2.03135,398,923 - 135,424,284 (+)NCBIT2T-CHM13v2.0
Uba5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399103,923,786 - 103,940,767 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9103,923,798 - 103,940,333 (-)EnsemblGRCm39 Ensembl
GRCm389104,046,587 - 104,063,176 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9104,046,599 - 104,063,134 (-)EnsemblGRCm38mm10GRCm38
MGSCv379103,948,918 - 103,965,451 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369103,905,860 - 103,921,466 (-)NCBIMGSCv36mm8
Celera9103,599,621 - 103,615,932 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.28NCBI
Uba5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88113,544,037 - 113,559,711 (-)NCBIGRCr8
mRatBN7.28104,665,241 - 104,680,915 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8104,665,046 - 104,680,894 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8110,312,345 - 110,328,010 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08108,511,538 - 108,527,203 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08106,354,238 - 106,369,903 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08112,578,607 - 112,594,192 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8112,578,590 - 112,594,261 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08111,967,198 - 111,981,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48109,109,592 - 109,124,197 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18109,129,046 - 109,143,652 (-)NCBI
Celera8104,030,471 - 104,045,054 (-)NCBICelera
Cytogenetic Map8q32NCBI
Uba5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555015,841,606 - 5,870,953 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555015,841,516 - 5,864,304 (-)NCBIChiLan1.0ChiLan1.0
UBA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22130,610,219 - 130,628,030 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13130,615,543 - 130,634,777 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03129,732,314 - 129,752,579 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13137,208,916 - 137,227,246 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3137,209,715 - 137,227,147 (+)Ensemblpanpan1.1panPan2
UBA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12329,645,755 - 29,658,587 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2329,645,966 - 29,659,019 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2329,620,276 - 29,633,519 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02330,159,284 - 30,172,532 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2330,159,776 - 30,172,962 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12329,855,266 - 29,868,510 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02329,912,394 - 29,925,642 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02330,160,514 - 30,173,360 (+)NCBIUU_Cfam_GSD_1.0
Uba5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560269,236,962 - 69,251,302 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365295,996,707 - 6,014,227 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365295,997,459 - 6,010,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1373,822,920 - 73,868,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11373,831,485 - 73,859,781 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21381,403,623 - 81,539,888 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11557,596,490 - 57,613,103 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1557,592,728 - 57,612,928 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604130,584,610 - 30,601,104 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000018892   ⟹   ENSHGLP00000018705
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247308,792,854 - 8,819,961 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000018893   ⟹   ENSHGLP00000018706
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247308,793,050 - 8,867,707 (+)Ensembl
RefSeq Acc Id: XM_004834233   ⟹   XP_004834290
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247308,792,770 - 8,819,957 (+)NCBI
RefSeq Acc Id: XM_004834234   ⟹   XP_004834291
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247308,791,691 - 8,819,957 (+)NCBI
RefSeq Acc Id: XM_021243800   ⟹   XP_021099459
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247308,799,682 - 8,819,957 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834290 (Get FASTA)   NCBI Sequence Viewer  
  XP_004834291 (Get FASTA)   NCBI Sequence Viewer  
  XP_021099459 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09874 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018705
Reference Protein Sequences
RefSeq Acc Id: XP_004834291   ⟸   XM_004834234
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004834290   ⟸   XM_004834233
- Peptide Label: isoform X1
- UniProtKB: G5BKR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099459   ⟸   XM_021243800
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000018705   ⟸   ENSHGLT00000018892
RefSeq Acc Id: ENSHGLP00000018706   ⟸   ENSHGLT00000018893


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013398 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000018892 ENTREZGENE
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro D-isomer_DH_CS1 UniProtKB/TrEMBL
  ThiF/MoeB/HesA UniProtKB/TrEMBL
  ThiF_NAD_FAD-bd UniProtKB/TrEMBL
  Ubiquitin-activating_enz UniProtKB/TrEMBL
KEGG Report hgl:101712064 UniProtKB/TrEMBL
NCBI Gene Uba5 ENTREZGENE
PANTHER PTHR10953 UniProtKB/TrEMBL
  UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 UniProtKB/TrEMBL
Pfam ThiF UniProtKB/TrEMBL
PROSITE D_2_HYDROXYACID_DH_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF69572 UniProtKB/TrEMBL
UniProt G5BKR3 ENTREZGENE, UniProtKB/TrEMBL