Ddb1 (damage specific DNA binding protein 1) - Rat Genome Database

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Gene: Ddb1 (damage specific DNA binding protein 1) Heterocephalus glaber
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Symbol: Ddb1
Name: damage specific DNA binding protein 1
RGD ID: 18903435
Description: ENCODES a protein that exhibits cullin family protein binding (ortholog); damaged DNA binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN apoptotic process (ortholog); biological process involved in interaction with symbiont (ortholog); cellular response to UV (ortholog); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); communication disorder (ortholog); congenital heart disease (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog); Cul4A-RING E3 ubiquitin ligase complex (ortholog); Cul4B-RING E3 ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA damage-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926871,000 - 897,777 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624926871,003 - 893,902 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ddb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926871,000 - 897,777 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624926871,003 - 893,902 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DDB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,299,451 - 61,333,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,299,451 - 61,342,596 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,066,923 - 61,100,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,823,495 - 60,857,242 (-)NCBINCBI36Build 36hg18NCBI36
Build 341160,823,499 - 60,857,125NCBI
Cytogenetic Map11q12.2NCBI
HuRef1157,394,763 - 57,428,510 (-)NCBIHuRef
CHM1_11160,949,958 - 60,983,704 (-)NCBICHM1_1
T2T-CHM13v2.01161,288,439 - 61,322,058 (-)NCBIT2T-CHM13v2.0
Ddb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,582,961 - 10,607,186 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,582,691 - 10,607,183 (+)EnsemblGRCm39 Ensembl
GRCm381910,605,568 - 10,629,828 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,605,327 - 10,629,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv371910,680,115 - 10,704,312 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,672,670 - 10,696,867 (+)NCBIMGSCv36mm8
Celera1911,301,601 - 11,325,808 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.66NCBI
Ddb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,677,810 - 216,703,605 (+)NCBIGRCr8
mRatBN7.21207,252,890 - 207,278,685 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,252,890 - 207,278,676 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,631,459 - 215,657,329 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,687,016 - 222,712,802 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,382,012 - 215,407,798 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,657,561 - 226,683,356 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,657,561 - 226,683,347 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,603,490 - 233,629,285 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41213,095,187 - 213,120,986 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1204,746,264 - 204,772,059 (+)NCBICelera
Cytogenetic Map1q43NCBI
Ddb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555116,209,777 - 6,233,594 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555116,209,777 - 6,233,594 (+)NCBIChiLan1.0ChiLan1.0
DDB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,467,451 - 62,501,152 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,511,126 - 63,544,583 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,599,422 - 56,633,140 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,964,235 - 59,997,805 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,964,235 - 59,997,805 (-)Ensemblpanpan1.1panPan2
DDB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11855,064,720 - 55,097,623 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1855,064,729 - 55,097,627 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1853,637,465 - 53,670,146 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01856,112,716 - 56,145,419 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1856,112,714 - 56,167,311 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11855,170,743 - 55,203,394 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01854,792,588 - 54,825,289 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,673,233 - 55,706,147 (+)NCBIUU_Cfam_GSD_1.0
Ddb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,596,653 - 11,628,774 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365811,710,382 - 1,742,598 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365811,710,382 - 1,742,598 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl210,171,502 - 10,201,598 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1210,171,554 - 10,201,602 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.229,718,733 - 9,748,620 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,508,712 - 12,543,127 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,508,443 - 12,544,913 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038109,887,958 - 109,922,218 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026124   ⟹   ENSHGLP00000025895
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624926871,000 - 897,777 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000026125   ⟹   ENSHGLP00000025896
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624926871,149 - 893,339 (+)Ensembl
RefSeq Acc Id: XM_004874353   ⟹   XP_004874410
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624926871,003 - 893,902 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004874410 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025895
GenBank Protein JAN97309 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004874410   ⟸   XM_004874353
- UniProtKB: A0A0N8EST0 (UniProtKB/TrEMBL),   G5AYG6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025895   ⟸   ENSHGLT00000026124
Ensembl Acc Id: ENSHGLP00000025896   ⟸   ENSHGLT00000026125


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018430 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026124 ENTREZGENE
Gene3D-CATH 1.10.150.910 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro Cleavage/polyA-sp_fac_asu_C UniProtKB/TrEMBL
  Cleavage/polyA-sp_fac_asu_N UniProtKB/TrEMBL
  RSE1/DDB1/CFT1/CPSF1 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101712635 UniProtKB/TrEMBL
NCBI Gene Ddb1 ENTREZGENE
PANTHER DNA REPAIR/RNA PROCESSING CPSF FAMILY UniProtKB/TrEMBL
Pfam CPSF_A UniProtKB/TrEMBL
  MMS1_N UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0N8EST0 ENTREZGENE, UniProtKB/TrEMBL
  G5AYG6 ENTREZGENE, UniProtKB/TrEMBL