Mst1r (macrophage stimulating 1 receptor) - Rat Genome Database

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Gene: Mst1r (macrophage stimulating 1 receptor) Heterocephalus glaber
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Symbol: Mst1r
Name: macrophage stimulating 1 receptor
RGD ID: 18932688
Description: ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN positive regulation of MAP kinase activity (ortholog); positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); response to virus (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 1 (ortholog); Chemical and Drug Induced Liver Injury (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN stress fiber (ortholog); vacuole (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: macrophage stimulating 1 receptor (c-met-related tyrosine kinase); macrophage-stimulating protein receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247303,800,749 - 3,822,389 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247303,802,452 - 3,818,593 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mst1r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247303,800,749 - 3,822,389 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247303,802,452 - 3,818,593 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MST1R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38349,887,002 - 49,903,873 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl349,886,902 - 49,903,873 (-)EnsemblGRCh38hg38GRCh38
GRCh37349,924,435 - 49,941,306 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,899,439 - 49,916,310 (-)NCBINCBI36Build 36hg18NCBI36
Build 34349,899,441 - 49,916,074NCBI
Celera349,890,532 - 49,907,401 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef349,982,720 - 49,999,587 (-)NCBIHuRef
CHM1_1349,876,510 - 49,893,392 (-)NCBICHM1_1
T2T-CHM13v2.0349,916,899 - 49,933,769 (-)NCBIT2T-CHM13v2.0
Mst1r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,784,057 - 107,797,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,784,072 - 107,797,582 (+)EnsemblGRCm39 Ensembl
GRCm389107,906,858 - 107,920,383 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,906,873 - 107,920,383 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,809,220 - 107,822,714 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,764,990 - 107,778,484 (+)NCBIMGSCv36mm8
Celera9107,515,111 - 107,528,610 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map959.07NCBI
Mst1r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,471,928 - 117,491,059 (+)NCBIGRCr8
mRatBN7.28108,596,100 - 108,611,441 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,597,299 - 108,612,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,224,119 - 114,237,556 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,423,306 - 112,436,743 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,266,082 - 110,279,519 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,686,601 - 116,700,132 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,686,601 - 116,700,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,040,918 - 116,054,449 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,175,977 - 113,189,511 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,195,431 - 113,208,968 (+)NCBI
Celera8107,901,807 - 107,915,501 (+)NCBICelera
Cytogenetic Map8q32NCBI
Mst1r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,775,033 - 1,787,990 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,774,726 - 1,789,662 (-)NCBIChiLan1.0ChiLan1.0
MST1R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2249,872,957 - 49,892,367 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1349,877,732 - 49,897,142 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0349,818,538 - 49,835,713 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1351,054,795 - 51,072,307 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl351,054,795 - 51,072,401 (-)Ensemblpanpan1.1panPan2
MST1R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,386,970 - 39,400,780 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,387,322 - 39,400,588 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2039,308,073 - 39,327,481 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02039,744,306 - 39,763,724 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2039,743,897 - 39,757,861 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,111,143 - 39,130,550 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02039,515,612 - 39,535,003 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02039,794,926 - 39,814,335 (+)NCBIUU_Cfam_GSD_1.0
Mst1r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560264,734,239 - 64,753,244 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365291,495,059 - 1,509,901 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365291,494,748 - 1,509,925 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MST1R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,409,555 - 32,421,920 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,401,623 - 32,423,614 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,579,209 - 35,603,505 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MST1R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,293,637 - 11,310,239 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,293,263 - 11,309,980 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041155,686,841 - 155,703,896 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000017752   ⟹   ENSHGLP00000017577
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247303,800,749 - 3,822,389 (-)Ensembl
RefSeq Acc Id: XM_004834066   ⟹   XP_004834123
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247303,802,818 - 3,818,593 (-)NCBI
RefSeq Acc Id: XM_013070163   ⟹   XP_012925617
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247303,802,818 - 3,818,593 (-)NCBI
RefSeq Acc Id: XM_013070175   ⟹   XP_012925629
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247303,802,818 - 3,818,521 (-)NCBI
RefSeq Acc Id: XM_021263911   ⟹   XP_021119570
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247303,802,453 - 3,818,593 (-)NCBI
RefSeq Acc Id: XM_021264049   ⟹   XP_021119708
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247303,802,452 - 3,818,593 (-)NCBI
RefSeq Acc Id: XM_021264097   ⟹   XP_021119756
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247303,802,818 - 3,818,593 (-)NCBI
RefSeq Acc Id: XP_021119708   ⟸   XM_021264049
- Peptide Label: isoform X4
- UniProtKB: G5BZX9 (UniProtKB/TrEMBL),   A0AAX6TGM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119570   ⟸   XM_021263911
- Peptide Label: isoform X1
- UniProtKB: G5BZX9 (UniProtKB/TrEMBL),   A0AAX6TEV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834123   ⟸   XM_004834066
- Peptide Label: isoform X3
- UniProtKB: G5BZX9 (UniProtKB/TrEMBL),   A0AAX6NPB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119756   ⟸   XM_021264097
- Peptide Label: isoform X5
- UniProtKB: G5BZX9 (UniProtKB/TrEMBL),   A0AAX6TF35 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925617   ⟸   XM_013070163
- Peptide Label: isoform X2
- UniProtKB: G5BZX9 (UniProtKB/TrEMBL),   A0AAX6QT31 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925629   ⟸   XM_013070175
- Peptide Label: isoform X6
- UniProtKB: A0AAX6QQY5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000017577   ⟸   ENSHGLT00000017752


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012578 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017752 ENTREZGENE
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
  YVTN repeat-like/Quinoprotein amine dehydrogenase UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  RTK UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_HGF/MSP_rcpt UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Mst1r ENTREZGENE
PANTHER MACROPHAGE-STIMULATING PROTEIN RECEPTOR UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/TrEMBL
Pfam PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  TIG UniProtKB/TrEMBL
PIRSF TyrPK_HGF-R UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  SEMA UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP E set domains UniProtKB/TrEMBL
  Plexin repeat UniProtKB/TrEMBL
  Protein kinase-like (PK-like) UniProtKB/TrEMBL
  Sema domain UniProtKB/TrEMBL
UniProt A0AAX6NPB9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QQY5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QT31 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TEV3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TF35 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TGM3 ENTREZGENE, UniProtKB/TrEMBL
  G5BZX9 ENTREZGENE, UniProtKB/TrEMBL