Symbol:
Nr5a2
Name:
nuclear receptor subfamily 5 group A member 2
RGD ID:
18934510
Description:
ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN acinar cell differentiation (ortholog); bile acid metabolic process (ortholog); calcineurin-mediated signaling (ortholog); ASSOCIATED WITH anovulation (ortholog); Chemical and Drug Induced Liver Injury (ortholog); colon cancer (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type:
protein-coding
RefSeq Status:
MODEL
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Biological Process
Only show annotations with direct experimental evidence (0 objects hidden)
Nr5a2 Naked Mole-Rat acinar cell differentiation acts_upstream_of_or_within ISO RGD:68500 9068941 PMID:25063451 MGI PMID:25063451 Nr5a2 Naked Mole-Rat bile acid metabolic process acts_upstream_of ISO RGD:68499 9068941 PMID:21614002 UniProt PMID:21614002 Nr5a2 Naked Mole-Rat bile acid metabolic process acts_upstream_of_or_within ISO MGI:3050234 9068941 PMID:15014077 MGI PMID:15014077 Nr5a2 Naked Mole-Rat bile acid metabolic process acts_upstream_of ISO RGD:68500 9068941 PMID:14766742 UniProt PMID:14766742 Nr5a2 Naked Mole-Rat bile acid metabolic process acts_upstream_of ISO RGD:68500 9068941 PMID:21614002 UniProt PMID:21614002 Nr5a2 Naked Mole-Rat calcineurin-mediated signaling ISO RGD:68353 9068941 RGD PMID:25057110|REF_RGD_ID:12904895 Nr5a2 Naked Mole-Rat cartilage development involved_in ISO RGD:68500 9068941 PMID:36905926 UniProt PMID:36905926 Nr5a2 Naked Mole-Rat cellular response to leukemia inhibitory factor acts_upstream_of_or_within ISO RGD:68500 9068941 PMID:20439489 MGI PMID:20439489 Nr5a2 Naked Mole-Rat cholesterol homeostasis acts_upstream_of_or_within ISO MGI:3050234 9068941 PMID:15014077 MGI PMID:15014077 Nr5a2 Naked Mole-Rat chromatin remodeling involved_in ISO RGD:68499 9068941 PMID:38409506 UniProt PMID:38409506 Nr5a2 Naked Mole-Rat chromatin remodeling involved_in ISO RGD:68500 9068941 PMID:37935903, PMID:39361745 UniProt PMID:37935903|PMID:39361745 Nr5a2 Naked Mole-Rat chromatin remodeling involved_in ISO RGD:68500 9068941 PMID:38409506 UniProt PMID:38409506 Nr5a2 Naked Mole-Rat embryonic cleavage involved_in ISO RGD:68500 9068941 PMID:15831456 UniProt PMID:15831456 Nr5a2 Naked Mole-Rat exocrine pancreas development involved_in ISO RGD:68500 9068941 PMID:21852532, PMID:29443959 UniProt PMID:21852532|PMID:29443959 Nr5a2 Naked Mole-Rat hormone-mediated signaling pathway involved_in IEA PANTHER:PTN000639709 150520179 TreeGrafter GO_REF:0000118 Nr5a2 Naked Mole-Rat inner cell mass cell differentiation involved_in ISO RGD:68500 9068941 PMID:38243114, PMID:38386558 UniProt PMID:38243114|PMID:38386558 Nr5a2 Naked Mole-Rat intracellular receptor signaling pathway involved_in IEA GO:0004879 150520179 GOC GO_REF:0000108 Nr5a2 Naked Mole-Rat morula formation involved_in ISO RGD:68500 9068941 PMID:37935903, PMID:38243114, PMID:38386558, PMID:39361745 UniProt PMID:37935903|PMID:38243114|PMID:38386558|PMID:39361745 Nr5a2 Naked Mole-Rat negative regulation of chondrocyte differentiation involved_in ISO RGD:68500 9068941 PMID:36905926 UniProt PMID:36905926 Nr5a2 Naked Mole-Rat negative regulation of inflammatory response involved_in ISO RGD:68500 9068941 PMID:17670946, PMID:29443959, PMID:30305617 UniProt PMID:17670946|PMID:29443959|PMID:30305617 Nr5a2 Naked Mole-Rat neurogenesis involved_in ISO RGD:68500 9068941 PMID:27447294 UniProt PMID:27447294 Nr5a2 Naked Mole-Rat pancreas morphogenesis acts_upstream_of_or_within ISO RGD:68500 9068941 PMID:25063451 MGI PMID:25063451 Nr5a2 Naked Mole-Rat positive regulation of DNA-templated transcription involved_in ISO RGD:68499 9068941 PMID:15143342 BHF-UCL PMID:15143342 Nr5a2 Naked Mole-Rat positive regulation of DNA-templated transcription involved_in ISO RGD:68500 9068941 PMID:30555544 UniProt PMID:30555544 Nr5a2 Naked Mole-Rat positive regulation of glucocorticoid biosynthetic process involved_in ISO RGD:68500 9068941 PMID:16923850, PMID:17670946 UniProt PMID:16923850|PMID:17670946 Nr5a2 Naked Mole-Rat positive regulation of stem cell differentiation involved_in ISO RGD:68500 9068941 PMID:27447294 UniProt PMID:27447294 Nr5a2 Naked Mole-Rat positive regulation of T cell activation involved_in ISO RGD:68500 9068941 PMID:31328159 UniProt PMID:31328159 Nr5a2 Naked Mole-Rat positive regulation of T cell anergy involved_in ISO RGD:68500 9068941 PMID:31328159 UniProt PMID:31328159 Nr5a2 Naked Mole-Rat positive regulation of T cell proliferation involved_in ISO RGD:68500 9068941 PMID:31328159 UniProt PMID:31328159 Nr5a2 Naked Mole-Rat positive regulation of tendon cell differentiation involved_in ISO RGD:68500 9068941 PMID:36905926 UniProt PMID:36905926 Nr5a2 Naked Mole-Rat positive regulation of transcription by RNA polymerase II involved_in ISO RGD:68500 9068941 PMID:20937355 BHF-UCL PMID:20937355 Nr5a2 Naked Mole-Rat positive regulation of transcription by RNA polymerase II involved_in ISO RGD:68499 9068941 PMID:15205472, PMID:27984042 UniProt PMID:15205472|PMID:27984042 Nr5a2 Naked Mole-Rat positive regulation of transcription by RNA polymerase II acts_upstream_of_or_within ISO RGD:68500 9068941 PMID:22977234 MGI PMID:22977234 Nr5a2 Naked Mole-Rat positive regulation of transcription by RNA polymerase II acts_upstream_of_or_within ISO MGI:3528835 9068941 PMID:15831456 MGI PMID:15831456 Nr5a2 Naked Mole-Rat positive regulation of transcription by RNA polymerase II involved_in ISO RGD:68500 9068941 PMID:12456679 NTNU_SB PMID:12456679 Nr5a2 Naked Mole-Rat positive regulation of transcription by RNA polymerase II involved_in ISO UniProtKB:P33242 9068941 PMID:19389484 BHF-UCL PMID:19389484 Nr5a2 Naked Mole-Rat positive regulation of viral genome replication involved_in ISO RGD:68499 9068941 PMID:19264593 BHF-UCL PMID:19264593 Nr5a2 Naked Mole-Rat primary ovarian follicle growth involved_in ISO RGD:68500 9068941 PMID:33441767 UniProt PMID:33441767 Nr5a2 Naked Mole-Rat regulation of cell population proliferation acts_upstream_of_or_within ISO MGI:88039 9068941 PMID:15684064 MGI PMID:15684064 Nr5a2 Naked Mole-Rat regulation of DNA-templated transcription involved_in IEA ARBA:ARBA00028138 150520179 UniProt GO_REF:0000117 Nr5a2 Naked Mole-Rat regulation of DNA-templated transcription involved_in IEA InterPro:IPR001628|InterPro:IPR013088 150520179 InterPro GO_REF:0000002 Nr5a2 Naked Mole-Rat regulation of transcription by RNA polymerase II involved_in IEA PANTHER:PTN000639709 150520179 TreeGrafter GO_REF:0000118 Nr5a2 Naked Mole-Rat Sertoli cell development involved_in ISO RGD:68500 9068941 PMID:35192609 UniProt PMID:35192609 Nr5a2 Naked Mole-Rat somatic stem cell population maintenance involved_in ISO RGD:68500 9068941 PMID:34397088 UniProt PMID:34397088 Nr5a2 Naked Mole-Rat spermatogenesis involved_in ISO RGD:68500 9068941 PMID:35192609 UniProt PMID:35192609 Nr5a2 Naked Mole-Rat tissue development involved_in IEA PANTHER:PTN000639709 150520179 TreeGrafter GO_REF:0000118 Nr5a2 Naked Mole-Rat zygotic genome activation involved_in ISO RGD:68500 9068941 PMID:36423263 UniProt PMID:36423263
Nr5a2 (Heterocephalus glaber - naked mole-rat)
NR5A2 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 200,027,710 - 200,177,415 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 200,027,614 - 200,177,420 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 199,996,838 - 200,146,543 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 198,263,393 - 198,413,175 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 196,728,426 - 196,878,205 NCBI Celera 1 173,119,461 - 173,269,192 (+) NCBI Celera Cytogenetic Map 1 q32.1 NCBI HuRef 1 171,163,369 - 171,312,952 (+) NCBI HuRef CHM1_1 1 201,419,353 - 201,569,071 (+) NCBI CHM1_1 T2T-CHM13v2.0 1 199,284,725 - 199,434,351 (+) NCBI T2T-CHM13v2.0
Nr5a2 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 1 136,770,300 - 136,888,186 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 1 136,770,309 - 136,888,186 (-) Ensembl GRCm39 Ensembl GRCm38 1 136,842,562 - 136,960,448 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 1 136,842,571 - 136,960,448 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 1 138,740,161 - 138,857,025 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 1 138,660,687 - 138,776,859 (-) NCBI MGSCv36 mm8 Celera 1 139,488,247 - 139,612,651 (-) NCBI Celera Cytogenetic Map 1 E4 NCBI cM Map 1 59.98 NCBI
Nr5a2 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 50,865,253 - 50,985,107 (-) NCBI GRCr8 mRatBN7.2 13 48,313,634 - 48,433,494 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 48,316,301 - 48,433,326 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 13 50,924,322 - 51,041,371 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 52,212,210 - 52,329,237 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 49,479,256 - 49,596,284 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 13 53,750,470 - 53,870,288 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 53,750,473 - 53,870,428 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 13 58,791,496 - 58,910,967 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 13 49,931,592 - 50,048,756 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 13 49,945,671 - 50,062,836 (-) NCBI Celera 13 48,623,262 - 48,740,634 (-) NCBI Celera Cytogenetic Map 13 q13 NCBI
Nr5a2 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955406 36,263,184 - 36,415,525 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955406 36,263,257 - 36,415,494 (+) NCBI ChiLan1.0 ChiLan1.0
NR5A2 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 1 49,206,752 - 49,357,599 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 1 49,168,065 - 49,318,860 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 1 175,625,140 - 175,775,955 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 1 179,934,573 - 180,083,607 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 1 179,934,573 - 180,083,607 (+) Ensembl panpan1.1 panPan2
NR5A2 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 7 2,925,915 - 3,062,118 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 7 2,927,326 - 3,062,348 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 7 2,609,186 - 2,746,673 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 7 2,572,723 - 2,710,945 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 7 2,575,836 - 2,711,009 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 7 2,555,273 - 2,692,729 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 7 2,656,611 - 2,794,291 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 7 2,688,192 - 2,825,725 (-) NCBI UU_Cfam_GSD_1.0
Nr5a2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024409344 74,848,490 - 74,960,157 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936567 4,084,608 - 4,212,854 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936567 4,084,161 - 4,194,858 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
NR5A2 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 10 22,715,735 - 22,865,364 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 10 22,727,865 - 22,866,905 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 10 27,281,190 - 27,424,774 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
NR5A2 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 25 29,230,358 - 29,380,617 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 25 29,233,558 - 29,379,922 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666055 30,239,494 - 30,260,729 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
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Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
RefSeq Acc Id:
XM_004860118 ⟹ XP_004860175
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624798 356,953 - 494,876 (-) NCBI
RefSeq Acc Id:
XM_004860119 ⟹ XP_004860176
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624798 356,962 - 494,873 (-) NCBI
RefSeq Acc Id:
XM_004860120 ⟹ XP_004860177
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624798 356,962 - 483,861 (-) NCBI
RefSeq Acc Id:
XM_004860121 ⟹ XP_004860178
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624798 356,962 - 480,628 (-) NCBI
RefSeq Acc Id:
XM_021240654 ⟹ XP_021096313
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624798 356,962 - 494,877 (-) NCBI
RefSeq Acc Id:
XM_021240655 ⟹ XP_021096314
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624798 356,962 - 480,378 (-) NCBI
RefSeq Acc Id:
XP_004860175 ⟸ XM_004860118
- Peptide Label:
isoform X1
- UniProtKB:
A0AAX6PV03 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_021096313 ⟸ XM_021240654
- Peptide Label:
isoform X2
- UniProtKB:
A0AAX6PVA4 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_004860176 ⟸ XM_004860119
- Peptide Label:
isoform X2
- UniProtKB:
A0AAX6PVA4 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_004860177 ⟸ XM_004860120
- Peptide Label:
isoform X4
- UniProtKB:
A0AAX6PVX1 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_004860178 ⟸ XM_004860121
- Peptide Label:
isoform X3
- UniProtKB:
A0AAX6PVZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_021096314 ⟸ XM_021240655
- Peptide Label:
isoform X3
- UniProtKB:
A0AAX6PVZ1 (UniProtKB/TrEMBL)