Cdc25b (cell division cycle 25B) - Rat Genome Database

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Gene: Cdc25b (cell division cycle 25B) Heterocephalus glaber
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Symbol: Cdc25b
Name: cell division cycle 25B
RGD ID: 18928989
Description: ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN female meiosis I (ortholog); oocyte maturation (ortholog); positive regulation of cytokinesis (ortholog); ASSOCIATED WITH breast carcinoma (ortholog); Chemical and Drug Induced Liver Injury (ortholog); diastolic heart failure (ortholog); FOUND IN centrosome (ortholog); spindle pole (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: M-phase inducer phosphatase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,882,516 - 4,892,925 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,871,275 - 4,892,730 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (ISO)
cytoplasm  (IEA)
nucleus  (IEA)
spindle pole  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cdc25b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,882,516 - 4,892,925 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,871,275 - 4,892,730 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CDC25B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,786,951 - 3,806,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,786,772 - 3,806,121 (+)EnsemblGRCh38hg38GRCh38
GRCh37203,767,598 - 3,786,762 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,724,401 - 3,734,762 (+)NCBINCBI36Build 36hg18NCBI36
Celera203,838,270 - 3,848,633 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,724,986 - 3,735,364 (+)NCBIHuRef
CHM1_1203,776,654 - 3,787,027 (+)NCBICHM1_1
T2T-CHM13v2.0203,817,891 - 3,837,037 (+)NCBIT2T-CHM13v2.0
Cdc25b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392131,028,356 - 131,040,431 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2131,028,869 - 131,040,417 (+)EnsemblGRCm39 Ensembl
GRCm382131,186,436 - 131,198,511 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,186,949 - 131,198,497 (+)EnsemblGRCm38mm10GRCm38
MGSCv372131,012,687 - 131,024,233 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,878,520 - 130,889,906 (+)NCBIMGSCv36mm8
Celera2132,410,981 - 132,422,509 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.29NCBI
Cdc25b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,860,148 - 138,870,287 (+)NCBIGRCr8
mRatBN7.23118,407,127 - 118,417,272 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,407,128 - 118,417,272 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,301,484 - 122,311,583 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,900,852 - 130,910,946 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,557,585 - 128,567,684 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,731,539 - 123,741,696 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,731,539 - 123,741,339 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,229,228 - 130,239,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,893,716 - 118,903,516 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,799,288 - 118,809,089 (+)NCBI
Celera3117,215,222 - 117,225,031 (+)NCBICelera
Cytogenetic Map3q36NCBI
Cdc25b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,629,132 - 14,650,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,637,295 - 14,647,181 (+)NCBIChiLan1.0ChiLan1.0
CDC25B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,749,003 - 4,769,167 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,745,828 - 4,765,995 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,877,255 - 3,883,458 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,626,097 - 3,645,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,626,107 - 3,645,179 (+)Ensemblpanpan1.1panPan2
CDC25B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,552,206 - 17,561,791 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,553,316 - 17,561,759 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,381,964 - 17,391,536 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02417,971,255 - 17,980,600 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2417,971,273 - 17,980,568 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,566,166 - 17,575,511 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,676,969 - 17,686,318 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,004,858 - 18,014,203 (-)NCBIUU_Cfam_GSD_1.0
Cdc25b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,465,682 - 166,482,670 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648514,897,050 - 14,914,034 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC25B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1731,910,825 - 31,929,242 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11731,910,824 - 31,929,418 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,244,262 - 36,262,979 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDC25B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,482,709 - 34,493,737 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl234,483,771 - 34,494,071 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660719,958,886 - 9,969,775 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000021972   ⟹   ENSHGLP00000021762
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247414,882,516 - 4,892,925 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000021973   ⟹   ENSHGLP00000021763
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247414,882,582 - 4,891,570 (+)Ensembl
RefSeq Acc Id: XM_004840737   ⟹   XP_004840794
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,882,252 - 4,892,730 (+)NCBI
RefSeq Acc Id: XM_004840739   ⟹   XP_004840796
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,882,242 - 4,892,730 (+)NCBI
RefSeq Acc Id: XM_004840741   ⟹   XP_004840798
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,871,275 - 4,892,730 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004840794 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840796 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840798 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021762
RefSeq Acc Id: XP_004840798   ⟸   XM_004840741
- Peptide Label: isoform X3
- UniProtKB: G5B4U8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840796   ⟸   XM_004840739
- Peptide Label: isoform X2
- UniProtKB: G5B4U8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840794   ⟸   XM_004840737
- Peptide Label: isoform X1
- UniProtKB: G5B4U8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000021763   ⟸   ENSHGLT00000021973
Ensembl Acc Id: ENSHGLP00000021762   ⟸   ENSHGLT00000021972


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015547 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000021972 ENTREZGENE
Gene3D-CATH Rhodanese-like domain UniProtKB/TrEMBL
InterPro MPI_Phosphatase UniProtKB/TrEMBL
  Rhodanese-like_dom UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Cdc25b ENTREZGENE
PANTHER M-PHASE INDUCER PHOSPHATASE 2 UniProtKB/TrEMBL
  M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 UniProtKB/TrEMBL
Pfam M-inducer_phosp UniProtKB/TrEMBL
  Rhodanese UniProtKB/TrEMBL
PRINTS MPIPHPHTASE UniProtKB/TrEMBL
PROSITE RHODANESE_3 UniProtKB/TrEMBL
SMART RHOD UniProtKB/TrEMBL
Superfamily-SCOP Rhodanese/Cell cycle control phosphatase UniProtKB/TrEMBL
UniProt G5B4U8 ENTREZGENE, UniProtKB/TrEMBL