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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Archazolid B
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Accession:CHEBI:188736 term browser browse the term
Synonyms:exact_synonym: [(1S)-1-[4-[(2S,3S,4E,6E,8S,9S,10R,11E,13Z,15Z,17S,18S,19E,22E)-10,18-dihydroxy-8-methoxy-3,7,9,13,15,17,20-heptamethyl-24-oxo-1-oxacyclotetracosa-4,6,11,13,15,19,22-heptaen-2-yl]-1,3-thiazol-2-yl]-3-methylbutyl] N-methylcarbamate;   [1-[4-[(4E,6E,11E,19E,22E)-10,18-dihydroxy-8-methoxy-3,7,9,13,15,17,20-heptamethyl-24-oxo-1-oxacyclotetracosa-4,6,11,13,15,19,22-heptaen-2-yl]-1,3-thiazol-2-yl]-3-methylbutyl] N-methylcarbamate
 related_synonym: Formula=C41H60N2O7S;   InChI=1S/C41H60N2O7S/c1-25(2)20-36(49-41(47)42-10)40-43-33(24-51-40)39-30(7)16-13-15-29(6)38(48-11)32(9)34(44)19-18-27(4)21-28(5)22-31(8)35(45)23-26(3)14-12-17-37(46)50-39/h12-13,15-19,21-25,30-32,34-36,38-39,44-45H,14,20H2,1-11H3,(H,42,47)/b16-13+,17-12+,19-18+,26-23+,27-21-,28-22-,29-15+/t30-,31-,32-,34+,35+,36-,38+,39-/m0/s1;   InChIKey=BYVUBCIRZIXXCV-OZCJWKDYSA-N;   SMILES=S1C(=NC([C@]2(OC(=O)C=CCC(=C[C@@H](O)[C@H](C=C(C=C(C=C[C@@H](O)[C@@H]([C@H](OC)C(=CC=C[C@@H]2C)C)C)C)C)C)C)[H])=C1)[C@@H](OC(=O)NC)CC(C)C
 xref: Chemspider:23303793
 xref_mesh: MESH:C519728


show annotations for term's descendants           Sort by:
Archazolid B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO archazolid B results in decreased expression of ABCA1 mRNA CTD PMID:25218289 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression ISO archazolid B results in increased expression of ACAT2 mRNA CTD PMID:25218289 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression ISO archazolid B results in increased expression of ALDOC mRNA CTD PMID:25218289 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO archazolid B results in increased expression of ANGPTL4 mRNA CTD PMID:25218289 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO archazolid B results in increased expression of ATF3 mRNA CTD PMID:25218289 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G C3h11orf96 similar to human chromosome 11 open reading frame 96 increases expression ISO archazolid B results in increased expression of C11ORF96 mRNA CTD PMID:25218289 NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523 		JBrowse link
G Car9 carbonic anhydrase 9 increases expression ISO archazolid B results in increased expression of CA9 mRNA CTD PMID:25218289 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO archazolid B results in decreased expression of CCL2 mRNA CTD PMID:25218289 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression ISO archazolid B results in decreased expression of CCN1 mRNA CTD PMID:25218289 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO archazolid B results in decreased expression of CCNB1 mRNA CTD PMID:25218289 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO archazolid B results in decreased expression of CDC20 mRNA CTD PMID:25218289 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 increases expression ISO archazolid B results in increased expression of CEMIP mRNA CTD PMID:25218289 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO archazolid B results in decreased expression of COL1A1 mRNA CTD PMID:25218289 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO archazolid B results in decreased expression of COL1A2 mRNA CTD PMID:25218289 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cpa4 carboxypeptidase A4 increases expression ISO archazolid B results in increased expression of CPA4 mRNA CTD PMID:25218289 NCBI chr 4:59,188,284...59,212,255
Ensembl chr 4:59,188,284...59,212,255 		JBrowse link
G Crym crystallin, mu increases expression ISO archazolid B results in increased expression of CRYM mRNA CTD PMID:25218289 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO archazolid B results in increased expression of DDIT3 mRNA CTD PMID:25218289 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddx10 DEAD-box helicase 10 decreases expression ISO archazolid B results in decreased expression of DDX10 mRNA CTD PMID:25218289 NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373 		JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO archazolid B results in increased expression of DEPP1 mRNA CTD PMID:25218289 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO archazolid B results in increased expression of DHCR24 mRNA CTD PMID:25218289 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO archazolid B results in decreased expression of DIO2 mRNA CTD PMID:25218289 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Diras3 DIRAS family GTPase 3 decreases expression ISO archazolid B results in decreased expression of DIRAS3 mRNA CTD PMID:25218289 NCBI chr 6:130,524,972...130,526,186
Ensembl chr 6:130,524,742...130,530,825 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression ISO archazolid B results in increased expression of EBP mRNA CTD PMID:25218289 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO archazolid B results in decreased expression of EFEMP1 mRNA CTD PMID:25218289 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression ISO archazolid B results in decreased expression of ENC1 mRNA CTD PMID:25218289 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO archazolid B results in increased expression of FDFT1 mRNA CTD PMID:25218289 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase increases expression ISO archazolid B results in increased expression of FDPS mRNA CTD PMID:25218289 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fjx1 four-jointed box kinase 1 decreases expression ISO archazolid B results in decreased expression of FJX1 mRNA CTD PMID:25218289 NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321 		JBrowse link
G Fst follistatin decreases expression ISO archazolid B results in decreased expression of FST mRNA CTD PMID:25218289 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO archazolid B results in increased expression of HMGCR mRNA CTD PMID:25218289 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO archazolid B results in increased expression of HMGCS1 mRNA CTD PMID:25218289 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hopx HOP homeobox decreases expression ISO archazolid B results in decreased expression of HOPX mRNA CTD PMID:25218289 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression ISO archazolid B results in decreased expression of ID1 mRNA CTD PMID:25218289 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO archazolid B results in decreased expression of ID3 mRNA CTD PMID:25218289 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO archazolid B results in increased expression of IGFBP1 mRNA CTD PMID:25218289 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO archazolid B results in increased expression of IGFBP3 mRNA CTD PMID:25218289 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il36b interleukin 36, beta increases expression ISO archazolid B results in increased expression of IL36B mRNA CTD PMID:25218289 NCBI chr 3:7,024,881...7,030,388
Ensembl chr 3:7,021,973...7,031,619 		JBrowse link
G Il6 interleukin 6 increases expression ISO archazolid B results in increased expression of IL6 mRNA CTD PMID:25218289 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO archazolid B results in increased expression of INSIG1 mRNA CTD PMID:25218289 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 increases expression ISO archazolid B results in increased expression of INSIG2 mRNA CTD PMID:25218289 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Krt80 keratin 80 decreases expression ISO archazolid B results in decreased expression of KRT80 mRNA CTD PMID:25218289 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO archazolid B results in increased expression of LDLR mRNA CTD PMID:25218289 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 decreases expression ISO archazolid B results in decreased expression of LRRN3 mRNA CTD PMID:25218289 NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330 		JBrowse link
G Lss lanosterol synthase increases expression ISO archazolid B results in increased expression of LSS mRNA CTD PMID:25218289 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 decreases expression ISO archazolid B results in decreased expression of LYPD1 mRNA CTD PMID:25218289 NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO archazolid B results in increased expression of MSMO1 mRNA CTD PMID:25218289 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression ISO archazolid B results in increased expression of MVD mRNA CTD PMID:25218289 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Mvk mevalonate kinase increases expression ISO archazolid B results in increased expression of MVK mRNA CTD PMID:25218289 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO archazolid B results in decreased expression of MYLIP mRNA CTD PMID:25218289 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295 		JBrowse link
G Ndp norrin cystine knot growth factor NDP decreases expression ISO archazolid B results in decreased expression of NDP mRNA CTD PMID:25218289 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO archazolid B results in increased expression of NDRG1 mRNA CTD PMID:25218289 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO archazolid B results in increased expression of NPC1 mRNA CTD PMID:25218289 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 increases expression ISO archazolid B results in increased expression of NPC2 mRNA CTD PMID:25218289 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression ISO archazolid B results in increased expression of NSDHL mRNA CTD PMID:25218289 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO archazolid B results in increased expression of PTGS2 mRNA CTD PMID:25218289 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog decreases expression ISO archazolid B results in decreased expression of RRS1 mRNA CTD PMID:25218289 NCBI chr 5:9,733,486...9,735,119
Ensembl chr 5:9,733,091...9,735,140 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO archazolid B results in increased expression of SC5D mRNA CTD PMID:25218289 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO archazolid B results in increased expression of SLC2A3 mRNA CTD PMID:25218289 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression ISO archazolid B results in increased expression of SPINK1 mRNA CTD PMID:25218289 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
G Sqle squalene epoxidase increases expression ISO archazolid B results in increased expression of SQLE mRNA CTD PMID:25218289 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 decreases expression ISO archazolid B results in decreased expression of TNFRSF21 mRNA CTD PMID:25218289 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO archazolid B results in increased expression of TRIB3 mRNA CTD PMID:25218289 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression ISO archazolid B results in decreased expression of TSC22D1 mRNA CTD PMID:25218289 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958 		JBrowse link
G Zp1 zona pellucida glycoprotein 1 increases expression ISO archazolid B results in increased expression of ZP1 mRNA CTD PMID:25218289 NCBI chr 1:207,560,881...207,567,261
Ensembl chr 1:207,560,881...207,567,261 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19848
    chemical entity 19846
      atom 19846
        nonmetal atom 19784
          oxygen atom 19527
            oxygen molecular entity 19527
              organooxygen compound 19175
                polyketide 11518
                  macrolide 7533
                    Archazolid B 64
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    p-block element atom 19796
                      carbon group element atom 19741
                        carbon atom 19737
                          organic molecular entity 19737
                            heteroorganic entity 19495
                              organochalcogen compound 19257
                                organooxygen compound 19175
                                  ester 17461
                                    carboxylic ester 16732
                                      lactone 13235
                                        macrocyclic lactone 7585
                                          macrolide 7533
                                            Archazolid B 64
paths to the root