| 620274 | Amph | amphiphysin | ENCODES a protein that exhibits phosphatase binding; protein-containing complex binding; phospholipid binding (ortholog); INVOLVED IN positive regulation of endocytosis; positive regulation of GTPase activity; learning (ortholog); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; ASSOCIA TED WITH COVID-19 (ortholog); FOUND IN axon terminus; extrinsic component of synaptic vesicle membrane; postsynaptic endocytic zone; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; ammonium chloride | 17 | 50435018 | 50678583 | Rat | 134 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 621786 | Bin1 | bridging integrator 1 | ENCODES a protein that exhibits GTPase binding; protein-containing complex binding; actin filament binding (ortholog); INVOLVED IN positive regulation of endocytosis; positive regulation of GTPase activity; synaptic vesicle endocytosis; ASSOCIATED WITH Alzheimer's disease (ortholog); autosomal domin ant nonsyndromic deafness 22 (ortholog); autosomal recessive centronuclear myopathy (ortholog); FOUND IN axon initial segment; axon terminus; cerebellar mossy fiber; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 18 | 24282840 | 24341461 | Rat | 251 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2149 | Areg | amphiregulin | ENCODES a protein that exhibits epidermal growth factor receptor binding; growth factor activity; receptor ligand activity (ortholog); INVOLVED IN epidermal growth factor receptor signaling pathway; glial cell proliferation; negative regulation of osteoblast differentiation; PARTICIPATES IN epiderma l growth factor/neuregulin signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms; Experimental Mammary Neoplasms; high grade glioma; FOUND IN extracellular space; cell surface (ortholog); cytoplasm (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate; 17beta-estradiol | 14 | 17256384 | 17265641 | Rat | 444 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2802 | Hmgb1 | high mobility group box 1 | ENCODES a protein that exhibits 5S rRNA binding; bent DNA binding; crossed form four-way junction DNA binding; INVOLVED IN actin cytoskeleton organization; cell morphogenesis; cellular response to interleukin-1; PARTICIPATES IN pro-inflammatory cytokine mediated pathway; cisplatin drug pathway; mism atch repair pathway; ASSOCIATED WITH Acute Experimental Pancreatitis; Acute Lung Injury; Acute-On-Chronic Liver Failure; FOUND IN cytosol; extracellular space; membrane raft; INTERACTS WITH (+)-pilocarpine; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol | 12 | 11009236 | 11015941 | Rat | 813 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1587112 | Hmgb1-ps33 | high-mobility group box 1, pseudogene 33 | PARTICIPATES IN base excision repair pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cadmium dichloride | 19 | 71943091 | 71944367 | Rat | 17 | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 1305515 | Rgs17 | regulator of G-protein signaling 17 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN response to amphetamine; ASSOCIATED WITH amphetamine abuse (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); nucleus (inferred); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 44627583 | 44729957 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310861 | Fam216a | family with sequence similarity 216, member A | INTERACTS WITH amphetamine; bisphenol A; cadmium atom | 12 | 39859307 | 39868450 | Rat | 57 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309391 | Tpd52l3 | TPD52 like 3 | INTERACTS WITH amphetamine; bisphenol A; C60 fullerene | 1 | 237195695 | 237197988 | Rat | 22 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1589336 | Tmed8 | transmembrane p24 trafficking protein family member 8 | INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A | 6 | 112537921 | 112572199 | Rat | 40 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 11382285 | Ceacam15 | CEA cell adhesion molecule 15 | INTERACTS WITH 17beta-estradiol; bisphenol A; amphotericin B (ortholog) | 1 | 86496487 | 86501454 | Rat | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 1307124 | Ankrd52 | ankyrin repeat domain 52 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 7 | 1390730 | 1410139 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595947 | Lrrc75a | leucine rich repeat containing 75A | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 47798028 | 47842577 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 727911 | Amigo2 | adhesion molecule with Ig like domain 2 | INVOLVED IN cerebellum development; heterophilic cell-cell adhesion; homophilic cell-cell adhesion; ASSOCIATED WITH Experimental Autoimmune Encephalomyelitis (ortholog); gastric adenocarcinoma (ortholog); melanoma (ortholog); FOUND IN nucleus (inferred); plasma membrane (inferred); INTERACTS WITH 17 alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 7 | 130270639 | 130273735 | Rat | 165 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 9302596 | Ervv-2 | endogenous retrovirus group V member 2, envelope | INTERACTS WITH amphetamine; paracetamol; 2-hydroxypropanoic acid (ortholog) | 3 | 139582024 | 139587909 | Rat | 7 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1585883 | Fam169b | family with sequence similarity 169, member B | INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol; amphetamine | 1 | 131288780 | 131378548 | Rat | 27 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1303079 | Amigo1 | adhesion molecule with Ig like domain 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN axonal fasciculation; axonogenesis; cellular response to L-glutamate; ASSOCIATED WITH schizophrenia (ortholog); FOUND IN neuronal cell body; pericellular basket; dendrite (ortholog); INTERACTS WITH 1-naphthy l isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 198511285 | 198516744 | Rat | 113 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 631413 | Amigo3 | adhesion molecule with Ig like domain 3 | ENCODES a protein that exhibits protein-containing complex binding; INVOLVED IN heterophilic cell-cell adhesion; negative regulation of neuron projection development; nervous system development; ASSOCIATED WITH Optic Nerve Injuries; sciatic neuropathy; Spinal Cord Compression; FOUND IN membrane (inf erred); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acetamide | 8 | 117620499 | 117622025 | Rat | 71 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3699 | Slc20a2 | solute carrier family 20 member 2 | ENCODES a protein that exhibits sodium:phosphate symporter activity; virus receptor activity (ortholog); INVOLVED IN positive regulation of bone mineralization (ortholog); PARTICIPATES IN phosphate transport pathway; ASSOCIATED WITH basal ganglia calcification (ortholog); basal ganglia disease (orth olog); calcinosis (ortholog); FOUND IN apical plasma membrane; brush border membrane; plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 16 | 76163315 | 76253881 | Rat | 144 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308637 | Ccdc90b | coiled-coil domain containing 90B | FOUND IN mitochondrion (ortholog); INTERACTS WITH amphetamine; bisphenol A; chlorpyrifos | 1 | 156045192 | 156058750 | Rat | 65 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311598 | Sin3a | SIN3 transcription regulator family member A | ENCODES a protein that exhibits protein-containing complex binding; RNA binding; chromatin binding (ortholog); INVOLVED IN cellular response to dopamine; cellular response to tert-butyl hydroperoxide; regulation of hormone levels; PARTICIPATES IN DNA modification pathway; Hedgehog signaling pathway; Huntington's disease pathway; ASSOCIATED WITH Fetal Growth Retardation; Hyperalgesia; transient cerebral ischemia; FOUND IN chromatin; nucleus; protein-containing complex; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 66377471 | 66432150 | Rat | 202 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1587989 | Sin3b | SIN3 transcription regulator family member B | ENCODES a protein that exhibits chromatin binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN cardiac muscle tissue development (ortholog); negative regulation of DNA-templated transcription (ortholog); skeletal muscle tissue development (ortholog); PARTICIPATES IN Hedgeho g signaling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN autosome (ortholog); cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 16 | 17157352 | 17194051 | Rat | 99 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1590831 | Amigo1-ps1 | adhesion molecule with Ig like domain 1, pseudogene 1 | | 2 | 213863282 | 213864489 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 2272 | Cartpt | CART prepropeptide | ENCODES a protein that exhibits neuropeptide hormone activity (inferred); INVOLVED IN adult feeding behavior; behavioral response to cocaine; cAMP biosynthetic process; ASSOCIATED WITH amnestic disorder; amphetamine abuse; cerebral infarction; FOUND IN cytoplasm ; extracellular space; neuronal cell body; INTERACTS WITH (3,4-dihydroxyphenyl)acetic acid; (S)-nicotine; 17beta-estradiol | 2 | 32989215 | 32991794 | Rat | 238 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560421 | Nemp2 | nuclear envelope integral membrane protein 2 | FOUND IN nuclear inner membrane (inferred); INTERACTS WITH acetamide; amphetamine; bisphenol A | 9 | 56353233 | 56372586 | Rat | 31 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305153 | Cfap184 | cilia and flagella associated protein 184 | FOUND IN cilium (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 14 | 78501256 | 78503715 | Rat | 55 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2004 | A2m | alpha-2-macroglobulin | ENCODES a protein that exhibits brain-derived neurotrophic factor binding; endopeptidase inhibitor activity; identical protein binding; INVOLVED IN acute inflammatory response to antigenic stimulus; acute-phase response; embryonic liver development; PARTICIPATES IN transforming growth factor-beta Sm ad dependent signaling pathway; Alzheimer's disease pathway; immune response pathway; ASSOCIATED WITH Burns; Cardiomegaly; Diabetic Cardiomyopathies; FOUND IN extracellular space; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; (S)-amphetamine | 4 | 156570163 | 156619870 | Rat | 347 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1594560 | Abitram | actin binding transcription modulator | ENCODES a protein that exhibits actin filament binding (ortholog); actin monomer binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); regulation of actin filament polymerization (ortholog); regulation of filopodium assembly (ortholog); FOUND IN dendrite (ortholog); filopodium tip (orth olog); growth cone (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 5 | 76301054 | 76308140 | Rat | 59 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565768 | Ablim1 | actin-binding LIM protein 1 | ENCODES a protein that exhibits actin binding (ortholog); INVOLVED IN axon guidance (ortholog); cilium assembly (ortholog); lamellipodium assembly (ortholog); ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN actin cytoskeleton (ortholog); lamellipodium (ortholog); postsynaptic density (ortholog); INTERACTS WITH 4,4'-diaminodiphenylmethane; amphetamine; atrazine | 1 | 266088868 | 266377169 | Rat | 168 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621467 | Adam1a | ADAM metallopeptidase domain 1a | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN male gonad development; binding of sperm to zona pellucida (ortholog); FOUND IN membrane raft (ortholog); INTERACTS WITH (S)-amph ;'>amphetamine; 17beta-estradiol; 2,4-dinitrotoluene | 12 | 40674460 | 40680988 | Rat | 69 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1591020 | Adat1 | adenosine deaminase, tRNA-specific 1 | ENCODES a protein that exhibits RNA binding (ortholog); tRNA-specific adenosine deaminase activity (ortholog); INVOLVED IN tRNA processing (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 19 | 56825153 | 56866136 | Rat | 65 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308263 | Adck1 | aarF domain containing kinase 1 | ENCODES a protein that exhibits ATP binding (inferred); protein kinase activity (inferred); INVOLVED IN negative regulation of mitochondrial fusion (ortholog); positive regulation of cristae formation (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2, 4-dinitrotoluene; amphetamine | 6 | 113005333 | 113107960 | Rat | 36 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310285 | Adgrf1 | adhesion G protein-coupled receptor F1 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); memory (ortholog); neuron projection development (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH amph le='font-weight:700;'>amphetamine; cocaine; Monobutylphthalate | 9 | 25158198 | 25210744 | Rat | 78 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620836 | Adgrl3 | adhesion G protein-coupled receptor L3 | ENCODES a protein that exhibits calcium ion binding (ortholog); cell adhesion mediator activity (ortholog); G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cell-cell adhesion (ortholog); excitatory syna pse assembly (ortholog); ASSOCIATED WITH enhanced behavioral response to amphetamine; hyperactivity; increased startle reflex; ASSOCIATED WITH Reperfusion Injury; attention deficit hyperactivity disorder (ortholog); FOUND IN axon (ortholog); cell-cell junction (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 14 | 26690891 | 27458132 | Rat | 178 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 127285662 | Adgrl3em1Huyc | adhesion G protein-coupled receptor L3; CRISPR/Cas9 induced mutant1, Huyc | ASSOCIATED WITH enhanced behavioral response to amphetamine; hyperactivity; increased startle reflex | | | | Rat | 4 | description | gene, allele |
| 1598311 | Agbl5 | AGBL carboxypeptidase 5 | ENCODES a protein that exhibits metallocarboxypeptidase activity (ortholog); tubulin binding (ortholog); INVOLVED IN C-terminal protein deglutamylation (ortholog); defense response to virus (ortholog); protein branching point deglutamylation (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); g enetic disease (ortholog); retinitis pigmentosa (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); midbody (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A | 6 | 31192281 | 31213494 | Rat | 119 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1590818 | Ak5 | adenylate kinase 5 | ENCODES a protein that exhibits nucleoside diphosphate kinase activity (ortholog); INVOLVED IN ATP metabolic process (inferred); nucleobase-containing compound metabolic process (inferred); nucleoside monophosphate phosphorylation (inferred); PARTICIPATES IN de novo purine biosynthetic pathway; ASSO CIATED WITH amphetamine abuse (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 2 | 244057240 | 244241372 | Rat | 103 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307642 | Alox12e | arachidonate 12-lipoxygenase, epidermal | ENCODES a protein that exhibits arachidonate 12(S)-lipoxygenase activity (ortholog); linoleate 13S-lipoxygenase activity (ortholog); INVOLVED IN arachidonate metabolic process; lipoxygenase pathway; PARTICIPATES IN lipoxygenase mediated pathway of arachidonic acid metabolism; arachidonic acid metabo lic pathway; linoleic acid metabolic pathway; FOUND IN cytoplasm (inferred); INTERACTS WITH 17beta-estradiol 3-benzoate; 3,7-dihydropurine-6-thione; amphetamine | 10 | 55533044 | 55540509 | Rat | 49 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310736 | Ankrd26 | ankyrin repeat domain 26 | INVOLVED IN glucose homeostasis (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of fat cell differentiation (ortholog); ASSOCIATED WITH blood platelet disease (ortholog); genetic disease (ortholog); Gigantism (ortholog); FOUND IN actin cytoskeleton (ortholog) ; centrosome (ortholog); INTERACTS WITH amphetamine; bisphenol A; flutamide | 4 | 153342901 | 153412321 | Rat | 93 | description | gene, protein-coding, MODEL [RefSeq] |
| 1311153 | Ankrd45 | ankyrin repeat domain 45 | INVOLVED IN cell population proliferation (ortholog); FOUND IN cleavage furrow (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 13 | 75957047 | 75984868 | Rat | 34 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1563946 | Ano8 | anoctamin 8 | ENCODES a protein that exhibits intracellularly calcium-gated chloride channel activity (ortholog); INVOLVED IN chloride transmembrane transport (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH amphetamine; fenvalerate; 17beta-estradiol (ortholog) | 16 | 18197829 | 18207205 | Rat | 37 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560565 | Ano9 | anoctamin 9 | ENCODES a protein that exhibits calcium channel activity (ortholog); channel activity (ortholog); chloride channel inhibitor activity (ortholog); INVOLVED IN calcium activated galactosylceramide scrambling (ortholog); calcium activated phosphatidylcholine scrambling (ortholog); calcium activated pho sphatidylserine scrambling (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN endoplasmic reticulum (ortholog); plasma membrane (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A | 1 | 205638571 | 205659780 | Rat | 74 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560514 | Aoah | acyloxyacyl hydrolase | ENCODES a protein that exhibits acyloxyacyl hydrolase activity (ortholog); calcium ion binding (ortholog); INVOLVED IN fatty acid metabolic process (ortholog); lipopolysaccharide catabolic process (ortholog); lipopolysaccharide metabolic process (ortholog); ASSOCIATED WITH amph 00;'>amphetamine abuse (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acetamide | 17 | 48503812 | 48745161 | Rat | 69 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310233 | Ap4m1 | adaptor related protein complex 4 subunit mu 1 | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); Golgi to endosome transport (ortholog); Golgi to lysosome transport (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog); hereditary spa stic paraplegia (ortholog); FOUND IN AP-4 adaptor complex (ortholog); early endosome (ortholog); trans-Golgi network (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amphetamine | 12 | 22163474 | 22171734 | Rat | 113 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562727 | Aqp12a | aquaporin 12A | ENCODES a protein that exhibits channel activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 9 | 101001939 | 101007425 | Rat | 31 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304938 | Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | ENCODES a protein that exhibits GTPase activator activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); INVOLVED IN negative regulation of cell migration (ortholog); negative regulation of Rac protein signal transdu ction (ortholog); negative regulation of Rho protein signal transduction (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); prostate cancer (ortholog); FOUND IN cytoplasm (ortholog); lamellipodium (ortholog); ruffle (ortholog); INTERACTS WITH 1,3-dinitrobenzene; amphetamine; atrazine | 18 | 30058739 | 30085415 | Rat | 104 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 62037 | Arc | activity-regulated cytoskeleton-associated protein | ENCODES a protein that exhibits mRNA binding; structural molecule activity (ortholog); INVOLVED IN learning; long-term memory; modulation of chemical synaptic transmission; ASSOCIATED WITH enhanced behavioral response to morphine; ASSOCIATED WITH anxiety disorder; Experimental Seizures; Hearing Loss ; FOUND IN actin cytoskeleton; extracellular vesicle; glutamatergic synapse; INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (S)-amphetamine; 1,2,4-trimethylbenzene | 7 | 108444959 | 108448413 | Rat | 304 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305053 | Arhgap18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of actin cytoskeleton organization (ortholog); regulation of actin filament polymerization (ortholog); regulation of cell motility (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (or tholog); cytoplasmic microtubule (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 1 | 20222948 | 20456827 | Rat | 168 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 735202 | Arhgap27 | Rho GTPase activating protein 27 | ENCODES a protein that exhibits GTPase activator activity; SH3 domain binding; INVOLVED IN receptor-mediated endocytosis; Rho protein signal transduction; FOUND IN endosome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 10 | 88780527 | 88813275 | Rat | 85 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306655 | Arvcf | ARVCF, delta catenin family member | ENCODES a protein that exhibits cadherin binding (ortholog); INVOLVED IN RNA splicing (ortholog); ASSOCIATED WITH COVID-19 (ortholog); DiGeorge syndrome (ortholog); long QT syndrome (ortholog); FOUND IN adherens junction (ortholog); cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 17be ta-estradiol; acetamide; amphetamine | 11 | 96092451 | 96150144 | Rat | 124 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306877 | Asmtl | acetylserotonin O-methyltransferase-like | ENCODES a protein that exhibits hydrolase activity (inferred); nucleoside triphosphate diphosphatase activity (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; amph phetamine; bis(2-ethylhexyl) phthalate | 12 | 21429119 | 21431847 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2320342 | Astn2 | astrotactin 2 | ENCODES a protein that exhibits calcium ion binding (ortholog); inositol 1,3,4,5 tetrakisphosphate binding (ortholog); INVOLVED IN establishment of body hair planar orientation (ortholog); negative regulation of protein localization to cell surface (ortholog); ASSOCIATED WITH amph t:700;'>amphetamine abuse (ortholog); autistic disorder (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2H (ortholog); FOUND IN cell pole (ortholog); endosome (ortholog); membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 5 | 83772988 | 84759439 | Rat | 121 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1561464 | Atad5 | ATPase family, AAA domain containing 5 | ENCODES a protein that exhibits DNA clamp unloader activity (ortholog); INVOLVED IN cell population proliferation (ortholog); DNA damage response (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); neurilemmoma (or tholog); ovarian carcinoma (ortholog); FOUND IN Elg1 RFC-like complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 65568569 | 65616379 | Rat | 116 | description | gene, protein-coding, MODEL [RefSeq] |
| 621862 | Atf2 | activating transcription factor 2 | ENCODES a protein that exhibits cAMP response element binding; protein-containing complex binding; sequence-specific DNA binding; INVOLVED IN amelogenesis; negative regulation of epithelial cell proliferation; negative regulation of transcription by RNA polymerase II; PARTICIPATES IN adenosine signa ling pathway; interleukin-12 signaling pathway; influenza A pathway; ASSOCIATED WITH Endotoxemia; Facial Nerve Injuries; glaucoma; FOUND IN CCAAT-binding factor complex; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 17alpha-ethynylestradiol | 3 | 79125814 | 79202896 | Rat | 386 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2165 | Atf3 | activating transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding (ortholog); INVOLVED IN positive regulation of cell population proliferation; positive regulation of transcript ion by RNA polymerase II; cellular response to amino acid starvation (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Myocardial Reperfusion Injury; Cardiomegaly (ortholog); cardiomyopathy (ortholog); FOUND IN CHOP-ATF3 complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (S)-amphetamine; 1,2,4-trimethylbenzene; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine | 13 | 105274103 | 105331653 | Rat | 801 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304940 | Atf7 | activating transcription factor 7 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); enzyme binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN heart development (ortholog); hematopoietic progenitor cell differentiation (ortholog); hep atocyte apoptotic process (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 7 | 135537351 | 135649188 | Rat | 87 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621006 | Atp6v0a2 | ATPase H+ transporting V0 subunit a2 | ENCODES a protein that exhibits proton transmembrane transporter activity (ortholog); INVOLVED IN cellular response to increased oxygen levels (ortholog); intracellular iron ion homeostasis (ortholog); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis path way; ASSOCIATED WITH Autosomal Recessive Cutis Laxa (ortholog); autosomal recessive cutis laxa type IIA (ortholog); congenital disorder of glycosylation Il (ortholog); FOUND IN acrosomal vesicle (ortholog); perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; amphetamine | 12 | 37608211 | 37640860 | Rat | 118 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311082 | Atp6v1c1 | ATPase H+ transporting V1 subunit C1 | ENCODES a protein that exhibits proton transmembrane transporter activity (ortholog); proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN synaptic vesicle lumen acidification (ortholog); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; ASSOCIATED WITH DOORS syndrome (ortholog); Neoplasm Metastasis (ortholog); oral squamous cell carcinoma (ortholog); FOUND IN apical part of cell; extrinsic component of synaptic vesicle membrane; plasma membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; Brodifacoum | 7 | 71719326 | 71757191 | Rat | 126 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310088 | Atp6v1g1 | ATPase H+ transporting V1 subunit G1 | ENCODES a protein that exhibits ATPase binding (ortholog); proton transmembrane transporter activity (ortholog); proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN cellular response to increased oxygen levels (ortholog); intracellular iron ion homeostasis (ortholog); s ynaptic vesicle lumen acidification (ortholog); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; FOUND IN extrinsic component of synaptic vesicle membrane; cytosol (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; amphetamine | 5 | 81976959 | 81983139 | Rat | 129 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305796 | Atr | ATR checkpoint kinase | ENCODES a protein that exhibits histone H2AXS139 kinase activity (ortholog); MutLalpha complex binding (ortholog); MutSalpha complex binding (ortholog); INVOLVED IN response to arsenic-containing substance; response to xenobiotic stimulus; cellular response to gamma radiation (ortholog); PARTICIPATE S IN p53 signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); alpha thalassemia-X-linked intellectual disability syndrome (ortholog); Alzheimer's disease (ortholog); FOUND IN ATR-ATRIP complex (ortholog); chromosome (ortholog); extrinsic component of synaptic vesicle membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; cisplatin | 8 | 105306299 | 105403742 | Rat | 303 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562692 | Atxn7 | ataxin 7 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN microtubule cytoskeleton organization (ortholog); negative regulation of insulin-like growth factor receptor signaling pathway (ortholog); negative regulation of microtubule depolymerization (ortholog); PARTICIPATES IN RNA pol ymerase II transcription initiation pathway; ASSOCIATED WITH Abnormal Reflexes (ortholog); Arsenic Poisoning (ortholog); attention deficit hyperactivity disorder (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); microtubule cytoskeleton (ortholog); INTERACTS WITH 17beta-estradiol; amphetamine; bisphenol A | 15 | 13547859 | 13693311 | Rat | 100 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620328 | B3galt4 | Beta-1,3-galactosyltransferase 4 | ENCODES a protein that exhibits N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (ortholog); INVOLVED IN ganglioside biosynthetic process (ortholog); PARTICIPATES IN ganglioside metabolic pathway; FOUND IN Golgi membrane (inferred); membrane (inferred); ribonucleoprotein compl ex (inferred); INTERACTS WITH (+)-schisandrin B; (S)-amphetamine; 1,2,4-trimethylbenzene | 20 | 4937974 | 4939549 | Rat | 91 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359221 | B4galt3 | beta-1,4-galactosyltransferase 3 | ENCODES a protein that exhibits beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity (ortholog); galactosyltransferase activity (ortholog); INVOLVED IN glucosylceramide metabolic process (ortholog); PARTICIPATES IN keratan sulfate biosynthetic pathway; lacto-series glycosphi ngolipid metabolic pathway; N-linked glycan biosynthetic pathway; FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 13 | 86223827 | 86229886 | Rat | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566122 | B9d2 | B9 domain containing 2 | ENCODES a protein that exhibits gamma-tubulin binding (ortholog); INVOLVED IN cilium assembly (ortholog); ASSOCIATED WITH ciliopathy (ortholog); Joubert syndrome (ortholog); Joubert syndrome 1 (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); ciliary transition zone (ortholo g); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 1 | 90315472 | 90323143 | Rat | 66 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 10059729 | Baiap3 | BAI1-associated protein 3 | ENCODES a protein that exhibits calcium ion binding (ortholog); phospholipid binding (ortholog); SNARE binding (ortholog); INVOLVED IN dense core granule maturation (ortholog); G protein-coupled receptor signaling pathway (ortholog); modulation of chemical synaptic transmission (ortholog); ASSOCIATE D WITH long QT syndrome (ortholog); FOUND IN cytosol (ortholog); dense core granule (ortholog); early endosome membrane (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; amphetamine | 10 | 14764768 | 14777516 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564639 | Bank1 | B-cell scaffold protein with ankyrin repeats 1 | ENCODES a protein that exhibits phospholipase binding (ortholog); protease binding (ortholog); protein tyrosine kinase binding (ortholog); INVOLVED IN B cell activation (ortholog); negative regulation of B cell activation (ortholog); negative regulation of interleukin-6 production (ortholog); ASSOCI ATED WITH autoimmune thyroiditis (ortholog); diffuse scleroderma (ortholog); Hashimoto Disease (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); INTERACTS WITH acetamide; alpha-Zearalanol; amphetamine | 2 | 227203998 | 227474008 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305037 | Baz2a | bromodomain adjacent to zinc finger domain, 2A | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); DNA binding (ortholog); histone binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); DNA methylation-dependent constitutive heterochromatin formation (ortholog); heterochromatin formation (ortholog); ASSOCIATE D WITH Prostatic Neoplasms (ortholog); FOUND IN chromatin silencing complex (ortholog); NoRC complex (ortholog); nuclear speck (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; amphetamine | 7 | 1107377 | 1145507 | Rat | 90 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 6498801 | Bbip1 | BBSome interacting protein 1 | INVOLVED IN B cell homeostasis (ortholog); cilium assembly (ortholog); eating behavior (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 18 (ortholog); hypogonadotropic hypogonadism 7 with or without anosmia (ortholog); FOUND IN BBSome (ortholog); ciliary basal bo dy (ortholog); ciliary membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 262950459 | 262964410 | Rat | 82 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309923 | Bcl11a | BCL11 transcription factor A | ENCODES a protein that exhibits protein kinase binding; DNA-binding transcription factor binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to L-glutamate; negative regulation of branching morphogenesis of a nerve; n egative regulation of dendrite development; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); apraxia (ortholog); FOUND IN postsynapse; nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2-methoxyethanol; amphetamine | 14 | 102230147 | 102325289 | Rat | 218 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1585128 | Bcl7a | BAF chromatin remodeling complex subunit BCL7A | INVOLVED IN cellular respiration (ortholog); cognition (ortholog); energy homeostasis (ortholog); FOUND IN SWI/SNF complex (ortholog); INTERACTS WITH amphetamine; bisphenol A; paraquat | 12 | 38872851 | 38904770 | Rat | 95 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1596570 | Bend3 | BEN domain containing 3 | ENCODES a protein that exhibits rDNA binding (ortholog); INVOLVED IN DNA methylation-dependent constitutive heterochromatin formation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of ATP metabolic process (ortholog); FOUND IN heterochromatin (o rtholog); nucleolus (ortholog); INTERACTS WITH amphetamine; bisphenol A; endosulfan | 20 | 48562383 | 48599194 | Rat | 83 | description | gene, protein-coding, MODEL [RefSeq] |
| 1591927 | Bfsp2 | beaded filament structural protein 2 | ENCODES a protein that exhibits structural constituent of eye lens (ortholog); INVOLVED IN cell maturation (ortholog); cytoskeleton organization (ortholog); intermediate filament cytoskeleton organization (ortholog); ASSOCIATED WITH cataract (ortholog); cataract 12 multiple types (ortholog); Develop mental Disabilities (ortholog); FOUND IN cytoplasm (ortholog); intermediate filament (ortholog); INTERACTS WITH amphetamine; atrazine; bisphenol A | 8 | 112885087 | 112942246 | Rat | 59 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306729 | Bicdl2 | BICD family like cargo adaptor 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 10 | 13196205 | 13204642 | Rat | 45 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1591724 | Bloc1s3 | biogenesis of lysosomal organelles complex-1, subunit 3 | ENCODES a protein that exhibits protein transmembrane transporter activity (ortholog); INVOLVED IN anterograde axonal transport (ortholog); anterograde synaptic vesicle transport (ortholog); blood coagulation (ortholog); ASSOCIATED WITH genetic disease (ortholog); Hermansky-Pudlak syndrome (ortholog ); Hermansky-Pudlak syndrome 8 (ortholog); FOUND IN BLOC-1 complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 88283864 | 88286244 | Rat | 96 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307403 | Bmi1 | BMI1 proto-oncogene, polycomb ring finger | ENCODES a protein that exhibits chromatin binding (ortholog); promoter-specific chromatin binding (ortholog); RING-like zinc finger domain binding (ortholog); INVOLVED IN cellular response to dexamethasone stimulus; cellular response to interleukin-1; regulation of kidney development; PARTICIPATES I N histone modification pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); acute pancreatitis (ortholog); chronic pancreatitis (ortholog); FOUND IN heterochromatin (ortholog); nuclear body (ortholog); nucleus (ortholog); INTERACTS WITH amphetamine; bisphenol A; cadmium atom | 17 | 86240683 | 86250044 | Rat | 245 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307059 | C1qtnf12 | C1q and TNF related 12 | ENCODES a protein that exhibits hormone activity (ortholog); INVOLVED IN negative regulation of gluconeogenesis (ortholog); negative regulation of inflammatory response (ortholog); positive regulation of D-glucose import across plasma membrane (ortholog); FOUND IN extracellular region (ortholog); ex tracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 5 | 171833854 | 171838229 | Rat | 67 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68942 | Cacna1g | calcium voltage-gated channel subunit alpha1 G | ENCODES a protein that exhibits low voltage-gated calcium channel activity; voltage-gated calcium channel activity; scaffold protein binding (ortholog); INVOLVED IN artery smooth muscle contraction; calcium ion import; calcium ion transport into cytosol; PARTICIPATES IN acebutolol pharmacodynamics p athway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Left Ventricular Hypertrophy; nephrotoxicity; brain disease (ortholog); FOUND IN cell body; dendrite; neuronal cell body; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine | 10 | 79851886 | 79919926 | Rat | 297 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621001 | Calcr | calcitonin receptor | ENCODES a protein that exhibits calcitonin binding; calcitonin receptor activity; amylin receptor activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway; cellular response to transforming growth factor beta stimulus; cellular response to tumor necr osis factor; ASSOCIATED WITH Herpes Simplex Encephalitis; hypercalcemia (ortholog); osteoporosis (ortholog); FOUND IN axon; neuronal cell body; acrosomal vesicle (ortholog); INTERACTS WITH ammonium chloride; amphetamine; benzo[a]pyrene | 4 | 32615955 | 32691075 | Rat | 158 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2262 | Camk2b | calcium/calmodulin-dependent protein kinase II beta | ENCODES a protein that exhibits calcium/calmodulin-dependent protein kinase activity; phospholipase binding; protein kinase binding; INVOLVED IN cell projection morphogenesis; cellular response to homocysteine; hippocampal neuron apoptotic process; PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; p38 MAPK signaling pathway; type II interferon signaling pathway; ASSOCIATED WITH Hearing Loss, Cisplatin-Induced; Apnea (ortholog); autism spectrum disorder (ortholog); FOUND IN dendrite; glutamatergic synapse; perikaryon; INTERACTS WITH (R)-noradrenaline; (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 85059166 | 85148121 | Rat | 315 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2279 | Cat | catalase | ENCODES a protein that exhibits catalase activity; aminoacylase activity (ortholog); antioxidant activity (ortholog); INVOLVED IN cellular response to growth factor stimulus; conditioned place preference; hydrogen peroxide catabolic process; PARTICIPATES IN disulfiram pharmacodynamics pathway; trypt ophan metabolic pathway; amyotrophic lateral sclerosis pathway; ASSOCIATED WITH alcohol use disorder; alcohol-associated liver disease; amphetamine abuse; FOUND IN extracellular space; peroxisomal matrix; peroxisome; INTERACTS WITH (+)-artemisinin; (+)-catechin; (+)-pilocarpine | 3 | 110297340 | 110329526 | Rat | 3351 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1587243 | Cbx4 | chromobox 4 | ENCODES a protein that exhibits chromatin binding (ortholog); enzyme binding (ortholog); histone H3K27me3 reader activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog) ; negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A | 10 | 104835685 | 104841727 | Rat | 178 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562189 | Ccdc14 | coiled-coil domain containing 14 | INVOLVED IN protein localization to centrosome (ortholog); substantia nigra development (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 11 | 79557267 | 79593128 | Rat | 65 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305591 | Ccdc15 | coiled-coil domain containing 15 | ENCODES a protein that exhibits antiporter activity (inferred); glucose 6-phosphate:phosphate antiporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN cilium assembly (ortholog); positive regulation of centriole elongation (ortholog); ASSOCIATED WITH Neurodevelopmen tal Disorders (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 45165297 | 45257641 | Rat | 72 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560873 | Ccdc66 | coiled-coil domain containing 66 | ENCODES a protein that exhibits identical protein binding (ortholog); microtubule binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN ciliary transition zone assembly (ortholog); cilium assembly (ortholog); detection of light stimulus involved in visual perception (ortholog ); ASSOCIATED WITH retinal degeneration (ortholog); retinitis pigmentosa (ortholog); FOUND IN axoneme (ortholog); centriolar satellite (ortholog); centrosome (ortholog); INTERACTS WITH amphetamine; bisphenol A; paracetamol | 16 | 2668810 | 2700717 | Rat | 72 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307429 | Ccdc88c | coiled-coil and HOOK domain protein 88C | ENCODES a protein that exhibits frizzled binding (ortholog); G-protein alpha-subunit binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN apical constriction (ortholog); cilium movement (ortholog); cilium organization (ortholog); ASSOCIATED WITH genetic disease (ort holog); hydrocephalus (ortholog); spastic ataxia (ortholog); FOUND IN apical junction complex (ortholog); cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 6 | 125899337 | 126019162 | Rat | 138 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1302992 | Cchcr1 | coiled-coil alpha-helical rod protein 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN protein export from nucleus (ortholog); ASSOCIATED WITH alopecia areata (ortholog); amphetamine abuse (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN centriole ( ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 3210383 | 3223187 | Rat | 82 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564120 | Ccn6 | cellular communication network factor 6 | ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN negative regulation of angiogenesis (ortholog); negative regulation of cell population proliferation (ortholog); regulation of mitochondrial membrane potential (ortholog); ASSOCIATED WITH arthropathy (ortholog); breast me taplastic carcinoma (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog); mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; amphetamine | 20 | 44123932 | 44139745 | Rat | 49 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1308007 | Ccr1l1 | chemokine (C-C motif) receptor 1-like 1 | ENCODES a protein that exhibits C-C chemokine receptor activity (inferred); chemokine receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemokine-mediated signaling pathway (inferred); chemotaxis (inferred); G protein-coupled receptor signaling pathway (inferr ed); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 132467425 | 132478489 | Rat | 30 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1585137 | Cd300e | Cd300e molecule | ENCODES a protein that exhibits cocaine binding (ortholog); INVOLVED IN immune response (ortholog); FOUND IN cell surface (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; acetamide; amphetamine | 10 | 100784452 | 100808988 | Rat | 39 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1596020 | Cd33 | CD33 molecule | ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine phosphatase activator activity (ortholog); sialic acid binding (ortholog); INVOLVED IN cell-cell adhesion (ortholog); Fc-gamma receptor signaling pathway (ortholog); immune response-inhibiting signal transductio n (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Alzheimer's disease (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bis(2-ethylhexyl) phthalate | 1 | 103071985 | 103086687 | Rat | 63 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2306 | Cd4 | Cd4 molecule | ENCODES a protein that exhibits immunoglobulin binding; protein kinase binding; protein tyrosine kinase binding; INVOLVED IN cellular response to ionomycin; positive regulation of calcium ion transport into cytosol; positive regulation of T cell proliferation; PARTICIPATES IN Arf family mediated sig naling pathway; interleukin-12 signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH Alcohol-Related Disorders; amphetamine abuse; Corneal Graft Rejection; FOUND IN cell surface; external side of plasma membrane; endoplasmic reticulum lumen (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 159355147 | 159381636 | Rat | 263 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2316 | Cd8a | CD8 subunit alpha | ENCODES a protein that exhibits protein kinase binding; identical protein binding (ortholog); MHC class I protein complex binding (ortholog); INVOLVED IN response to methamphetamine hydrochloride; cell surface receptor signaling pathway (ortholog); cytotoxic T c ell differentiation (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; antigen processing and presentation pathway; primary immunodeficiency pathway; ASSOCIATED WITH amphetamine abuse; brain infarction; acquired immunodeficiency syndrome (ortholog); FOUND IN cell surface; external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; 1-naphthyl isothiocyanate | 4 | 104924116 | 104928353 | Rat | 177 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306771 | Cdan1 | codanin 1 | INVOLVED IN cell maturation (ortholog); cell morphogenesis (ortholog); chromatin organization (ortholog); ASSOCIATED WITH congenital dyserythropoietic anemia (ortholog); congenital dyserythropoietic anemia type I (ortholog); congenital dyserythropoietic anemia type Ia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endomembrane system (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 3 | 128129664 | 128143520 | Rat | 78 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307260 | Cdc42bpg | CDC42 binding protein kinase gamma | ENCODES a protein that exhibits ATP binding (ortholog); magnesium ion binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN protein phosphorylation (ortholog); FOUND IN cell leading edge (ortholog); cytosol (ortholog); INTERACTS WITH acrylamide; alpha-Zearalanol; amph style='font-weight:700;'>amphetamine | 1 | 213037603 | 213057764 | Rat | 95 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 70514 | Cdk5 | cyclin-dependent kinase 5 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase activity; cytoskeletal protein binding; ephrin receptor binding; INVOLVED IN cellular response to amyloid-beta; cortical actin cytoskeleton organization; DNA damage response; PARTICIPATES IN dopamine signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; Reelin signaling pathway; ASSOCIATED WITH Alzheimer's disease; brain ischemia; depressive disorder; FOUND IN axon; cytoplasm; dendrite; INTERACTS WITH (+)-schisandrin B; (S)-amphetamine; (S)-colchicine | 4 | 11647098 | 11651606 | Rat | 411 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 629472 | Cdk5r1 | cyclin-dependent kinase 5 regulatory subunit 1 | ENCODES a protein that exhibits cadherin binding; calcium ion binding; cyclin-dependent protein serine/threonine kinase activator activity; INVOLVED IN embryo development ending in birth or egg hatching; G protein-coupled acetylcholine receptor signaling pathway; ionotropic glutamate receptor signal ing pathway; PARTICIPATES IN Reelin signaling pathway; Alzheimer's disease pathway; ASSOCIATED WITH Brain Hypoxia-Ischemia; hypothyroidism; Spinal Cord Reperfusion Injury; FOUND IN axon; contractile muscle fiber; cytoplasm; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 65981692 | 65985831 | Rat | 274 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564182 | Cecr2 | CECR2, histone acetyl-lysine reader | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); cochlea development (ortholog); execution phase of apoptosis (ortholog); ASSOCIATED WITH anencephaly (ortholog); neural tube defect (ortholog); FOUND IN CERF complex (o rtholog); euchromatin (ortholog); ISWI-type complex (ortholog); INTERACTS WITH 17beta-estradiol; amphetamine; bisphenol A | 4 | 155562576 | 155670253 | Rat | 97 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1565619 | Cep120 | centrosomal protein 120 | INVOLVED IN astral microtubule organization (ortholog); cell population proliferation (ortholog); centrosome cycle (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); Desbuquois dysplasia (ortholog); familial erythrocytosis 2 (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); INTERACTS WITH amphetamine; bisphenol A; methoxychlor | 18 | 49326266 | 49388380 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305348 | Cep152 | centrosomal protein 152 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN centriole replication (ortholog); centrosome duplication (ortholog); de novo centriole assembly involved in multi-ciliated epithelial cell differentiation (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); genet ic disease (ortholog); microcephaly (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; amphetamine | 3 | 133243979 | 133332271 | Rat | 102 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561243 | Cep164 | centrosomal protein 164 | INVOLVED IN cilium assembly (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN 9+2 motile cilium (ortholog); apical part of cell (ortholog); centriole (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amph tyle='font-weight:700;'>amphetamine; bisphenol A | 8 | 54967621 | 55031264 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562262 | Cep250 | centrosomal protein 250 | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium assembly (ortholog); detection of light stimulus involved in visual perception (ortholog); ASSOCIATED WITH Cone-Rod Dystrophy and Hearing Loss 2 (ortholog); fundus dystrophy (ortholog); optic atrophy (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 3 | 164931033 | 164976210 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593368 | Cfap119 | cilia and flagella associated protein 119 | INVOLVED IN gene expression (ortholog); single fertilization (ortholog); sperm flagellum assembly (ortholog); FOUND IN acrosomal vesicle; axoneme; cytoplasm; INTERACTS WITH amphetamine; bisphenol A; Cuprizon | 1 | 191627662 | 191647429 | Rat | 37 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559942 | Cfap44 | cilia and flagella associated protein 44 | ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN cell morphogenesis (ortholog); cilium organization (ortholog); flagellated sperm motility (ortholog); ASSOCIATED WITH spermatogenic failure 20 (ortholog); INTERACTS WITH acrylamide; amphe tamine; bisphenol A | 11 | 69704997 | 69789998 | Rat | 74 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1561559 | Cfap45 | cilia and flagella associated protein 45 | ENCODES a protein that exhibits AMP binding (ortholog); INVOLVED IN cerebrospinal fluid circulation (ortholog); epithelial cilium movement involved in determination of left/right asymmetry (ortholog); establishment of left/right asymmetry (ortholog); ASSOCIATED WITH malignant mesothelioma (ortholog) ; tetralogy of Fallot (ortholog); visceral heterotaxy 11 (ortholog); FOUND IN 9+0 motile cilium (ortholog); 9+2 motile cilium (ortholog); axonemal B tubule inner sheath (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 13 | 87521831 | 87545236 | Rat | 99 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620428 | Cfh | complement factor H | ENCODES a protein that exhibits complement component C3b binding (ortholog); heparan sulfate proteoglycan binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide; cellular response to lipopolysaccharide; cellular response to type II interferon; PARTICIPATES IN coagulation cascade pathway; complement system pathway; Staphylococcus aureus infection pathway; ASSOCIATED WITH amphetamine abuse; atypical hemolytic-uremic syndrome; Hemorrhagic Shock; FOUND IN extracellular space; axon (ortholog); cell surface (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 13 | 54063079 | 54164523 | Rat | 366 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311923 | Chd3 | chromodomain helicase DNA binding protein 3 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN centrosome cycle (ortholog); chromatin organization (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATED WITH pancreatic carcinoma; autism spectrum disorder (ortholog); basal cell carcinoma (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 10 | 54562437 | 54588842 | Rat | 177 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310465 | Chd6 | chromodomain helicase DNA binding protein 6 | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); transcription coregulator binding (ortholog); INVOLVED IN cell redox homeostasis (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 sign aling pathway; ASSOCIATED WITH neuroblastoma (ortholog); Prostatic Neoplasms (ortholog); transitional cell carcinoma (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 3 | 170016204 | 170177480 | Rat | 103 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311083 | Chmp1a | charged multivesicular body protein 1A | ENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); cell division (ortholog); PARTICIPATES IN endocytosis pathway; ASSOCI ATED WITH genetic disease (ortholog); intellectual disability (ortholog); pontocerebellar hypoplasia (ortholog); FOUND IN amphisome membrane (ortholog); autophagosome membrane (ortholog); condensed nuclear chromosome (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 2-methoxyethanol | 19 | 68146672 | 68154952 | Rat | 141 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593500 | Chmp1b | charged multivesicular body protein 1B | ENCODES a protein that exhibits identical protein binding (ortholog); MIT domain binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); cell division (ortholog); PARTICIPATES IN endocytosis pathway; FOUND IN amph 'font-weight:700;'>amphisome membrane (ortholog); autophagosome membrane (ortholog); endosome membrane (ortholog); INTERACTS WITH bisphenol A; dibutyl phthalate; gentamycin | 18 | 63010270 | 63012800 | Rat | 82 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305050 | Chmp2a | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (ortholog); phosphatidylcholine binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); establishment of protein localization (ortholog); PARTICIPATES IN endocytos is pathway; FOUND IN amphisome membrane (ortholog); autophagosome membrane (ortholog); chromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 1 | 82731212 | 82735088 | Rat | 101 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306781 | Chmp2b | charged multivesicular body protein 2B | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN modulation of chemical synaptic transmission; regulation of modification of postsynaptic structure; regulation of postsynapse organization; PARTICIPATES IN autophagy pathway; endocytosis pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); frontotemporal dementia and/or amyotrophic lateral sclerosis 7 (ortholog); Frontotemporal Lobar Degeneration (ortholog); FOUND IN glutamatergic synapse; postsynaptic density; amphisome membrane (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; Brodifacoum | 11 | 16783971 | 16810500 | Rat | 162 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309846 | Chmp4b | charged multivesicular body protein 4B | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); exit from mitosis (ortholog); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH cataract 31 multiple types (or tholog); FOUND IN amphisome membrane (ortholog); autophagosome membrane (ortholog); cytoplasm (ortholog); INTERACTS WITH 2-methoxyethanol; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 3 | 163631054 | 163671569 | Rat | 121 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564543 | Chmp4c | charged multivesicular body protein 4C | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); late endosome to lysosome transport (ortholog); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH Ovarian Neoplasms (ortholog); FOUND IN amph ='font-weight:700;'>amphisome membrane (ortholog); autophagosome membrane (ortholog); Flemming body (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 93299152 | 93336075 | Rat | 126 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305968 | Chmp5 | charged multivesicular body protein 5 | INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); FOUND IN amphisome membrane (o rtholog); autophagosome membrane (ortholog); cytosol (ortholog); INTERACTS WITH acrylamide; amphetamine; benzo[a]pyrene | 5 | 60877369 | 60894512 | Rat | 132 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565325 | Chmp6 | charged multivesicular body protein 6 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); late endosome to lysosome transport (ortholog); PARTICIPATES IN endocytosis pathway; FOUND IN amphisome membrane (ortholog); autophagosome membrane (ortholog); endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 10 | 105690400 | 105696070 | Rat | 113 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308779 | Chmp7 | charged multivesicular body protein 7 | INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); exit from mitosis (ortholog); PARTICIPATES IN endocytosis pathway; FOUND IN amphisome membrane (ortholog); autophagosome membrane (ortholog); chromatin (ortholog); INTERACTS WITH 2,3,7,8-tetr achlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 15 | 51200759 | 51215992 | Rat | 109 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2342 | Chrm1 | cholinergic receptor, muscarinic 1 | ENCODES a protein that exhibits G protein-coupled acetylcholine receptor activity; INVOLVED IN G protein-coupled acetylcholine receptor signaling pathway; neuromuscular synaptic transmission; positive regulation of intracellular protein transport; PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; G protein mediated signaling pathway via Galphaq family; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH asthma (ortholog); brain ischemia (ortholog); epilepsy (ortholog); FOUND IN asymmetric synapse; axon terminus; dendrite; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; acetylcholine | 1 | 214996180 | 215012136 | Rat | 229 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621216 | Chst10 | carbohydrate sulfotransferase 10 | ENCODES a protein that exhibits HNK-1 sulfotransferase activity; sulfotransferase activity; INVOLVED IN androgen metabolic process (ortholog); estrogen metabolic process (ortholog); learning (ortholog); PARTICIPATES IN O-linked glycan biosynthetic pathway; ASSOCIATED WITH autism spectrum disorder (o rtholog); FOUND IN Golgi membrane; INTERACTS WITH ammonium chloride; amphetamine; atrazine | 9 | 48588575 | 48618487 | Rat | 66 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309199 | Cirsr | corepressor of RBPJ and splicing regulator | ENCODES a protein that exhibits histone deacetylase binding (ortholog); protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN in utero embryonic development (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of trans cription by RNA polymerase II (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN centrosome (ortholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 3 | 78566438 | 78596309 | Rat | 84 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566110 | Clec1a | C-type lectin domain family 1, member A | ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN cell recognition (ortholog); defense response to fungus (ortholog); immune response (ortholog); ASSOCIATED WITH aspergillosis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acryl amide; amphetamine | 4 | 164561385 | 164588593 | Rat | 54 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359298 | Clec4e | C-type lectin domain family 4, member E | ENCODES a protein that exhibits calcium ion binding (ortholog); glycolipid binding (ortholog); pattern recognition receptor activity (ortholog); INVOLVED IN antifungal innate immune response (ortholog); defense response to bacterium (ortholog); Fc-gamma receptor signaling pathway (ortholog); PARTICI PATES IN tuberculosis pathway; ASSOCIATED WITH Brain Injuries (ortholog); lung disease (ortholog); FOUND IN membrane (ortholog); phagocytic vesicle membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine | 4 | 158292624 | 158298607 | Rat | 131 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562513 | Clec9a | C-type lectin domain containing 9A | ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN positive regulation of cytokine production (ortholog); receptor-mediated endocytosis (ortholog); FOUND IN cell surface (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amph >amphetamine | 4 | 164546323 | 164561380 | Rat | 48 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564680 | Col28a1 | collagen type XXVIII alpha 1 chain | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN cell adhesion (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); FOUND IN basement membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; atrazine | 4 | 37036303 | 37189435 | Rat | 40 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304773 | Cop1 | COP1, E3 ubiquitin ligase | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of fatty acid biosynthetic process (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein ca tabolic process (ortholog); PARTICIPATES IN p53 signaling pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH abnormal circadian regulation of systemic arterial blood pressure; salt-sensitive hypertension; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN Golgi membrane; Cul4A-RING E3 ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 13 | 73954058 | 74095283 | Rat | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1594623 | Cox10 | cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 | ENCODES a protein that exhibits geranylgeranyl diphosphate synthase activity (ortholog); protoheme IX farnesyltransferase activity (ortholog); INVOLVED IN aerobic respiration (ortholog); copper ion homeostasis (ortholog); cytochrome complex assembly (ortholog); PARTICIPATES IN acute intermittent por phyria pathway; erythropoietic porphyria pathway; hereditary coproporphyria pathway; ASSOCIATED WITH cytochrome-c oxidase deficiency disease (ortholog); genetic disease (ortholog); Leigh disease (ortholog); FOUND IN cytochrome complex (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 10 | 49130209 | 49242009 | Rat | 108 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1598052 | Cox14 | cytochrome c oxidase assembly factor COX14 | ENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN mitochondrial respiratory chain complex IV assembly (ortholog); ASSOCIATED WITH mitochondrial complex IV deficiency nuclear type 10 (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog) ; INTERACTS WITH 3-chloropropane-1,2-diol; amphetamine; bisphenol A | 7 | 132731069 | 132733159 | Rat | 58 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306406 | Cpsf1 | cleavage and polyadenylation specific factor 1 | ENCODES a protein that exhibits enzyme binding (ortholog); mRNA 3'-UTR AU-rich region binding (ortholog); INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; ASSOCIATED WITH Diseas e Progression (ortholog); Myopia 27 (ortholog); retinitis pigmentosa 1 (ortholog); FOUND IN mRNA cleavage and polyadenylation specificity factor complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,6-dinitrotoluene; amphetamine; bisphenol A | 7 | 110200078 | 110210644 | Rat | 78 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563719 | Cracr2a | calcium release activated channel regulator 2A | ENCODES a protein that exhibits calcium ion binding (ortholog); G protein activity (ortholog); GTPase activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); endosomal transport (ortholog); intracellular protein localization (ortholog); FOUND IN cytoplasm ( ortholog); Golgi membrane (ortholog); immunological synapse (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 4 | 162094247 | 162207926 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560911 | Cracr2b | calcium release activated channel regulator 2B | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN store-operated calcium entry (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 205987957 | 205993515 | Rat | 60 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2403 | Crhbp | corticotropin releasing hormone binding protein | ENCODES a protein that exhibits corticotropin-releasing hormone binding; peptide binding; INVOLVED IN cellular response to cocaine; cellular response to estradiol stimulus; cellular response to estrogen stimulus; PARTICIPATES IN corticotropin-releasing hormone signaling pathway; ASSOCIATED WITH depr essive disorder; nicotine withdrawal syndrome; obesity; FOUND IN axon terminus; cytoplasm; dendrite; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 28427139 | 28439446 | Rat | 179 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620330 | Cs | citrate synthase | ENCODES a protein that exhibits citrate synthase activity; acyltransferase activity, acyl groups converted into alkyl on transfer (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process; citrate metabolic process; heart development; PARTICIPATES IN citric acid cycl e pathway; fumaric aciduria pathway; mitochondrial complex II deficiency pathway; ASSOCIATED WITH bipolar disorder; Brain Hypoxia-Ischemia; Cardiomegaly; FOUND IN mitochondrion; mitochondrial matrix (ortholog); INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 2,2,2-tetramine | 7 | 1348389 | 1374624 | Rat | 306 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305103 | Csmd1 | CUB and Sushi multiple domains 1 | INVOLVED IN conditioned place preference (ortholog); female gonad development (ortholog); gene expression (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN membrane (inferred); I NTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; aflatoxin B1 | 16 | 78920549 | 80520710 | Rat | 79 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563106 | Ctc1 | CST telomere replication complex component 1 | ENCODES a protein that exhibits G-rich strand telomeric DNA binding (ortholog); single-stranded DNA binding (ortholog); telomeric DNA binding (ortholog); INVOLVED IN bone marrow development (ortholog); chromosome organization (ortholog); DNA damage response (ortholog); ASSOCIATED WITH Autosomal Rece ssive Dyskeratosis Congenita (ortholog); brain disease (ortholog); calcinosis (ortholog); FOUND IN chromosome, telomeric region (ortholog); CST complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 54212537 | 54234146 | Rat | 113 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308181 | Ctsf | cathepsin F | ENCODES a protein that exhibits cysteine-type peptidase activity (ortholog); INVOLVED IN immune system process (inferred); proteolysis (inferred); ASSOCIATED WITH Developmental Disease (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred); end omembrane system (inferred); intracellular organelle lumen (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 211582169 | 211587917 | Rat | 114 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61810 | Ctsk | cathepsin K | ENCODES a protein that exhibits collagen binding (ortholog); cysteine-type endopeptidase activity (ortholog); cysteine-type peptidase activity (ortholog); INVOLVED IN bone resorption; cellular response to transforming growth factor beta stimulus; cellular response to tumor necrosis factor; PARTICIPA TES IN rheumatoid arthritis pathway; Toll-like receptor signaling pathway; ASSOCIATED WITH Alveolar Bone Loss; Experimental Arthritis; intracranial aneurysm; FOUND IN extracellular space; external side of plasma membrane (ortholog); lysosome (ortholog); INTERACTS WITH (S)-amphetamine; 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol | 2 | 185747548 | 185758512 | Rat | 303 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68355 | Cubn | cubilin | ENCODES a protein that exhibits cargo receptor activity; hemoglobin binding; identical protein binding; INVOLVED IN cobalamin catabolic process; cobalamin transport; endocytic hemoglobin import into cell; ASSOCIATED WITH Diabetic Nephropathies; amphetamine abuse (ortholog); autism spectrum disorder (ortholog); FOUND IN apical plasma membrane; brush border membrane; clathrin-coated pit; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl | 17 | 81293619 | 81501694 | Rat | 182 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621528 | Cxcr3 | C-X-C motif chemokine receptor 3 | ENCODES a protein that exhibits C-X-C chemokine receptor activity; C-C chemokine receptor activity (ortholog); C-X-C chemokine binding (ortholog); INVOLVED IN calcium-mediated signaling; positive regulation of cytosolic calcium ion concentration; T cell chemotaxis; PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Brain Hypoxia-Ischemia; Delayed Hypersensitivity; dilated cardiomyopathy; FOUND IN external side of plasma membrane; cell surface (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | X | 70884293 | 70886944 | Rat | 215 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 727915 | Cyp27a1 | cytochrome P450, family 27, subfamily a, polypeptide 1 | ENCODES a protein that exhibits cholesterol 26-hydroxylase activity; Hsp70 protein binding; vitamin D3 25-hydroxylase activity; INVOLVED IN cholesterol metabolic process; bile acid biosynthetic process (ortholog); bile acid metabolic process (ortholog); PARTICIPATES IN bile acid biosynthetic pathway ; bile acid signaling pathway; cerebrotendinous xanthomatosis pathway; ASSOCIATED WITH extrahepatic cholestasis; atherosclerosis (ortholog); autism spectrum disorder (ortholog); FOUND IN mitochondrial inner membrane; INTERACTS WITH (+)-schisandrin B; (25R)-cholest-5-ene-3beta,26-diol; (S)-amphetamine | 9 | 83712402 | 83743222 | Rat | 386 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619797 | Cysltr2 | cysteinyl leukotriene receptor 2 | ENCODES a protein that exhibits cysteinyl leukotriene receptor activity (ortholog); INVOLVED IN cellular response to hypoxia; negative regulation of glial cell proliferation; positive regulation of angiogenesis; PARTICIPATES IN endothelin signaling pathway; calcium/calcium-mediated signaling pathway ; ASSOCIATED WITH Pneumococcal Meningitis; Reperfusion Injury; aspirin-induced respiratory disease (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH ammonium chloride; amphetamine; bisphenol A | 15 | 54599043 | 54638314 | Rat | 88 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561687 | Dach2 | dachshund family transcription factor 2 | INVOLVED IN development of primary female sexual characteristics (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amphetamine | X | 82644374 | 83210181 | Rat | 52 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307211 | Dcbld1 | discoidin, CUB and LCCL domain containing 1 | ASSOCIATED WITH intellectual disability (ortholog); melanoma (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 20 | 32161241 | 32254391 | Rat | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310435 | Dcstamp | dendrocyte expressed seven transmembrane protein | INVOLVED IN cellular response to transforming growth factor beta stimulus; cellular response to tumor necrosis factor; mononuclear cell differentiation; ASSOCIATED WITH amphetamine abuse (ortholog); endometriosis (ortholog); Paget's disease of bone (ortholog); F OUND IN cell surface (ortholog); endoplasmic reticulum membrane (ortholog); endosome membrane (ortholog); INTERACTS WITH bisphenol A; dioxygen; paraquat | 7 | 72692364 | 72706983 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306675 | Ddx11 | DEAD/H-box helicase 11 | ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); ATP-dependent activity, acting on DNA (ortholog); ATP-dependent activity, acting on RNA (ortholog); INVOLVED IN cellular response to bleomycin (ortholog); cellular response to cisplatin (ortholog); cellular response to hydroxyur ea (ortholog); ASSOCIATED WITH Chromosome Breakage (ortholog); genetic disease (ortholog); microcephaly (ortholog); FOUND IN centrosome (ortholog); chromatin (ortholog); midbody (ortholog); INTERACTS WITH amphetamine; bisphenol A; C60 fullerene | 9 | 113204886 | 113309692 | Rat | 116 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620671 | Deaf1 | DEAF1 transcription factor | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; behavioral fear resp onse (ortholog); embryonic skeletal system development (ortholog); ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); fibrillar center (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 1 | 205831428 | 205865106 | Rat | 128 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559541 | Defb24 | defensin beta 24 | ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); INVOLVED IN innate immune response (ortholog); ASSOCIATED WITH female reproductive system disease (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil; amph style='font-weight:700;'>amphetamine | 3 | 161506850 | 161512983 | Rat | 35 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308441 | Dennd1b | DENN domain containing 1B | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN endocytic recycling (ortholog); positive regulation of GTPase activity (ortholog); positive regulation of T-helper 2 cell cytokine production (ortholog); ASSOCIATED WIT H autistic disorder (ortholog); COVID-19 (ortholog); Crohn's disease (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; gentamycin | 13 | 53096717 | 53324372 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308489 | Dennd4c | DENN domain containing 4C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); protein localization to plasma membrane (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathwa y; Rab family mediated signaling pathway; FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); insulin-responsive compartment (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 5 | 106316942 | 106421484 | Rat | 89 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2318606 | Dennd5b | DENN domain containing 5B | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN positive regulation of triglyceride transport (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amph span>etamine | 4 | 183688039 | 183821012 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308012 | Dennd6b | DENN domain containing 6B | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); FOUND IN recycling endosome (inferred); INTERACTS WITH (+)-schisandrin B; 4,4'-sulfonyldiphenol; amphetamine | 7 | 122139159 | 122154720 | Rat | 47 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560914 | Dgke | diacylglycerol kinase epsilon | ENCODES a protein that exhibits ATP-dependent diacylglycerol kinase activity (ortholog); kinase activity (ortholog); INVOLVED IN diacylglycerol metabolic process (ortholog); lipid phosphorylation (ortholog); modulation of chemical synaptic transmission (ortholog); ASSOCIATED WITH atypical hemolytic- uremic syndrome (ortholog); genetic disease (ortholog); hemolytic-uremic syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 10 | 74348931 | 74374509 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1588686 | Dhdh | dihydrodiol dehydrogenase | ENCODES a protein that exhibits D-xylose 1-dehydrogenase (NADP+) activity (ortholog); INVOLVED IN D-xylose catabolic process (ortholog); PARTICIPATES IN pentose and glucuronate interconversion pathway; phase I biotransformation pathway via cytochrome P450; ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 105088108 | 105102560 | Rat | 72 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311165 | Dhx35 | DEAH-box helicase 35 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN in utero embryonic development (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acetamide; amph ght:700;'>amphetamine | 3 | 167869971 | 167927300 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306837 | Dhx37 | DEAH-box helicase 37 | ENCODES a protein that exhibits U3 snoRNA binding (ortholog); INVOLVED IN brain development (ortholog); positive regulation of male gonad development (ortholog); ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Anorchia (ortholog); coloboma of optic nerve (ortholog); epilepsy (ortholog); FOUND IN cytoplasm (ortholog); nuclear membrane (ortholog); nucleolus (ortholog); INTERACTS WITH amphetamine; bisphenol A; metformin | 12 | 36856119 | 36876245 | Rat | 92 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310340 | Dhx57 | DExH-box helicase 57 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 6 | 20474889 | 20528556 | Rat | 70 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309381 | Dicer1 | dicer 1 ribonuclease III | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); miRNA binding (ortholog); pre-miRNA binding (ortholog); INVOLVED IN cellular response to glucose stimulus; cellular response to hydrogen peroxide; cellular response to hypoxia; PARTICIPATES IN microRNA pathway; ASSOCIATED WITH m iddle cerebral artery infarction; breast cancer (ortholog); Breast Neoplasms (ortholog); FOUND IN axon; dendrite; endoplasmic reticulum-Golgi intermediate compartment; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 6 | 129392298 | 129457252 | Rat | 334 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305671 | Dip2b | disco-interacting protein 2 homolog B | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of peptidyl-lysine acetylation (ortholog); ASSOCIATED WITH absence epilepsy (ortholog); autism spectrum disorder (ortholog); autosomal dominant intellec tual developmental disorder type FRA12A (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); dendrite (ortholog); INTERACTS WITH amphetamine; atrazine; bisphenol A | 7 | 133053393 | 133231430 | Rat | 83 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1594179 | Dmwd | DM1 locus, WD repeat containing | ENCODES a protein that exhibits deubiquitinase activator activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 1 | 87850475 | 87857263 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306791 | Dna2 | DNA replication helicase/nuclease 2 | ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); 5'-flap endonuclease activity (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN base-excision repair (ortholog); DNA double-strand break processing (ortholog); DNA replication (ortholog); PARTICIPATES IN homologous rec ombination pathway of double-strand break repair; DNA replication pathway; ASSOCIATED WITH isolated growth hormone deficiency type IA (ortholog); mitochondrial myopathy (ortholog); FOUND IN chromosome, telomeric region (inferred); mitochondrial nucleoid (inferred); mitochondrion (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 20 | 25660339 | 25689285 | Rat | 81 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564414 | Dnajc27 | DnaJ heat shock protein family (Hsp40) member C27 | ENCODES a protein that exhibits GTPase activity (ortholog); INVOLVED IN positive regulation of ERK1 and ERK2 cascade (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 6 | 32788215 | 32842418 | Rat | 53 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1583840 | Dnmbp | dynamin binding protein | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN cilium assembly (ortholog); regulation of cell shape (ortholog); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; ASSOCIATED WITH cataract 48 (ortholog); FOUND IN Golgi apparatus; presy napse; synapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 252685406 | 252778642 | Rat | 123 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 735124 | Dpagt1 | dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 | ENCODES a protein that exhibits UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity (ortholog); UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity (ortholog); INVOLVED IN dolichol-linked oligosaccharide biosynthetic process ( ortholog); protein N-linked glycosylation (ortholog); PARTICIPATES IN N-linked glycan biosynthetic pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation Ij (ortholog); FOUND IN Golgi apparatus (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 53560869 | 53567625 | Rat | 113 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311445 | Dus4l | dihydrouridine synthase 4-like | ENCODES a protein that exhibits flavin adenine dinucleotide binding (inferred); nucleotide binding (inferred); oxidoreductase activity (inferred); INVOLVED IN tRNA dihydrouridine synthesis (ortholog); ASSOCIATED WITH congenital disorder of glycosylation type IIi (ortholog); INTERACTS WITH (+)-schisa ndrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 6 | 53955609 | 53970050 | Rat | 63 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1307457 | Dusp19 | dual specificity phosphatase 19 | ENCODES a protein that exhibits JUN kinase phosphatase activity (ortholog); MAP-kinase scaffold activity (ortholog); mitogen-activated protein kinase kinase binding (ortholog); INVOLVED IN JNK cascade (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of MAPK cascade (ort holog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FOUND IN cytoplasm (ortholog); INTERACTS WITH amphetamine; bisphenol A; cobalt dichloride | 3 | 85945289 | 86081289 | Rat | 63 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311053 | Dux4 | double homeobox 4 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN apoptotic process (ortholog); n egative regulation of cell population proliferation (ortholog); negative regulation of G0 to G1 transition (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); facioscapulohumeral muscular dystrophy (ortholog); FOUND IN cytoplasm (ortholog); nuclear membrane (ortholog); nucleolus (ortholog); INTERACTS WITH amphetamine; bisphenol A; Cuprizon | 16 | 1565290 | 1575317 | Rat | 54 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307701 | Dzip1 | DAZ interacting zinc finger protein 1 | ENCODES a protein that exhibits BBSome binding (ortholog); molecular adaptor activity (ortholog); protein sequestering activity (ortholog); INVOLVED IN ciliary basal body organization (ortholog); cilium assembly (ortholog); cilium organization (ortholog); ASSOCIATED WITH autosomal dominant intellect ual developmental disorder 61 (ortholog); mitral valve prolapse (ortholog); Myxomatous Mitral Valve Prolapse 3 (ortholog); FOUND IN centriolar satellite (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A | 15 | 102363392 | 102417085 | Rat | 138 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563278 | Dzip3 | DAZ interacting zinc finger protein 3 | ENCODES a protein that exhibits phosphatase binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); RNA binding (ortholog); INVOLVED IN protein polyubiquitination (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; amph 0;'>amphetamine; bisphenol A | 11 | 65286190 | 65356314 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565023 | Ecd | ecdysoneless cell cycle regulator | ENCODES a protein that exhibits histone acetyltransferase binding (ortholog); INVOLVED IN cell population proliferation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of G1/S transition of mitotic cell cycle (ortholog); FOUND IN cytoplasm (ortholog); cyt osol (ortholog); nucleoplasm (ortholog); INTERACTS WITH amphetamine; paracetamol; thioacetamide | 15 | 4016411 | 4047899 | Rat | 63 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306898 | Edc3 | enhancer of mRNA decapping 3 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN deadenylation-independent decapping of nuclear-transcribed mRNA (inferred); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 50 (ortholog); FOUND IN cytoplasmic ribonucleoprotein granule (ortholog); INTERACTS WITH amphetamine; bisphenol A; fenvalerate | 8 | 67002032 | 67047563 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1588887 | Edil3 | EGF like and discoidin domains 3 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN positive regulation of cell-substrate adhesion (ortholog); ASSOCIATED WITH osteoarthritis (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofura n; amphetamine | 2 | 21625604 | 22140380 | Rat | 86 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309782 | Eed | embryonic ectoderm development | ENCODES a protein that exhibits chromatin binding; enzyme activator activity (ortholog); identical protein binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II; spinal cord development; cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN h istone modification pathway; ASSOCIATED WITH transient cerebral ischemia; autism spectrum disorder (ortholog); Cohen-Gibson Syndrome (ortholog); FOUND IN chromatin silencing complex (ortholog); ESC/E(Z) complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 1 | 153280419 | 153307537 | Rat | 124 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1597535 | Eeig1 | estrogen-induced osteoclastogenesis regulator 1 | INVOLVED IN positive regulation of osteoclast differentiation (ortholog); FOUND IN cytoplasm (ortholog); membrane raft (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; amphetamine | 3 | 36220170 | 36252377 | Rat | 103 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566407 | Efhb | EF hand domain family, member B | ENCODES a protein that exhibits calcium ion sensor activity (ortholog); INVOLVED IN flagellated sperm motility (ortholog); regulation of calcineurin-NFAT signaling cascade (ortholog); regulation of store-operated calcium entry (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); axonemal microtubule (ortholog); sperm flagellum (ortholog); INTERACTS WITH amphetamine; bisphenol A; Cuprizon | 9 | 6608791 | 6680104 | Rat | 59 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2544 | Egr1 | early growth response 1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; double-stranded DNA binding; INVOLVED IN cellular response to antibiotic; cellular response to cAMP; cellular response to follicle-stimulating hormone stimulus; PARTICIPATES IN long term potentiation; prion disease pathway; ASSOCIATED WITH Brain Hypoxia-Ischemia; breast cancer; cocaine dependence; FOUND IN cytoplasm; nucleus; chromatin (ortholog); INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; (S)-amphetamine | 18 | 26737078 | 26740877 | Rat | 1195 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307588 | Ehmt1 | euchromatic histone lysine methyltransferase 1 | ENCODES a protein that exhibits C2H2 zinc finger domain binding (ortholog); histone H3K27 methyltransferase activity (ortholog); histone H3K9 dimethyltransferase activity (ortholog); INVOLVED IN response to fungicide; beige fat cell differentiation (ortholog); brown fat cell differentiation (ortholo g); PARTICIPATES IN histone modification pathway; lysine degradation pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); autistic disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN chromatin (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 4-amino-2,6-dinitrotoluene; amphetamine; bisphenol A | 3 | 27978888 | 28127178 | Rat | 181 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311439 | Eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 | ENCODES a protein that exhibits eukaryotic translation initiation factor 2alpha kinase activity (ortholog); protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN positive regulation of protein phosphorylation; cellular response to amino acid starvation (ortholog); cellular response to cold (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; hepatitis C pathway; influenza A pathway; ASSOCIATED WITH pulmonary venoocclusive disease; amino acid metabolic disorder (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; amphetamine | 3 | 125810207 | 125895574 | Rat | 198 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306144 | Eif4g1 | eukaryotic translation initiation factor 4 gamma 1 | ENCODES a protein that exhibits eukaryotic initiation factor 4E binding; ATP binding (ortholog); mRNA binding (ortholog); INVOLVED IN lung development; response to ethanol; behavioral fear response (ortholog); PARTICIPATES IN translation initiation pathway; myocarditis pathway; RNA transport pathway ; ASSOCIATED WITH Myocardial Ischemia; autistic disorder (ortholog); COVID-19 (ortholog); FOUND IN eukaryotic translation initiation factor 4F complex; postsynapse; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amphetamine | 11 | 93726322 | 93746387 | Rat | 216 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305294 | Eif4g2 | eukaryotic translation initiation factor 4, gamma 2 | ENCODES a protein that exhibits translation factor activity, RNA binding (ortholog); translation initiation factor activity (ortholog); INVOLVED IN heart development; positive regulation of axon extension; positive regulation of dendritic spine development; PARTICIPATES IN translation initiation pat hway; myocarditis pathway; RNA transport pathway; ASSOCIATED WITH hypertension; renovascular hypertension; liver benign neoplasm (ortholog); FOUND IN axon; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (S)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 174616102 | 174628252 | Rat | 143 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1307968 | Elane | elastase, neutrophil expressed | ENCODES a protein that exhibits cytokine binding (ortholog); endopeptidase activity (ortholog); heparin binding (ortholog); INVOLVED IN leukocyte migration involved in inflammatory response; positive regulation of leukocyte tethering or rolling; acute inflammatory response to antigenic stimulus (ort holog); PARTICIPATES IN systemic lupus erythematosus pathway; ASSOCIATED WITH Acute Lung Injury; Edema; Experimental Pancreatitis; FOUND IN azurophil granule (ortholog); cell surface (ortholog); cytoplasm (ortholog); INTERACTS WITH amphetamine; andrographolide; anilines | 7 | 10467877 | 10469725 | Rat | 214 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1598663 | Elk1 | ETS transcription factor ELK1 | ENCODES a protein that exhibits chromatin binding; double-stranded DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; INVOLVED IN cellular response to gamma radiation; cellular response to lipid; cellular response to testosterone stimulus; PARTICIPATES IN adenosine s ignaling pathway; hypoxia inducible factor pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH anxiety disorder; Brain Injuries; transient cerebral ischemia; FOUND IN axon terminus; dendrite; mitochondrial membrane; INTERACTS WITH (R)-noradrenaline; (S)-amphetamine; (S)-nicotine | X | 3692367 | 3709252 | Rat | 279 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1305343 | Emilin2 | elastin microfibril interfacer 2 | INVOLVED IN negative regulation of cell migration (ortholog); positive regulation of angiogenesis (ortholog); positive regulation of apoptotic process (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; DDT | 9 | 118607312 | 118667087 | Rat | 104 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619725 | Entpd6 | ectonucleoside triphosphate diphosphohydrolase 6 | ENCODES a protein that exhibits CDP phosphatase activity; GDP phosphatase activity; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; INVOLVED IN response to calcium ion; response to magnesium ion; PARTICIPATES IN purine metabolic pathway; pyrimidine metabolic pathway; ASSOCIATED WITH obesity (ortholog); seminoma (ortholog); FOUND IN cell surface; extracellular space; extracellular region (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 3 | 160036055 | 160058580 | Rat | 82 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306107 | Entrep3 | endosomal transmembrane epsin interactor 3 | ENCODES a protein that exhibits WW domain binding (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 2 | 176886903 | 176893047 | Rat | 69 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304680 | Epha1 | Eph receptor A1 | ENCODES a protein that exhibits ephrin receptor activity (ortholog); fibronectin binding (ortholog); protein kinase binding (ortholog); INVOLVED IN positive regulation of angiogenesis; cell surface receptor protein tyrosine kinase signaling pathway (ortholog); negative regulation of cell migration ( ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH Alzheimer's disease (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Colorectal Neoplasms (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH aflatoxin B1; alpha-Zearalanol; amphetamine | 4 | 72213022 | 72227543 | Rat | 178 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311509 | Ercc6 | ERCC excision repair 6, chromatin remodeling factor | ENCODES a protein that exhibits ATP binding (ortholog); ATP-dependent activity, acting on DNA (ortholog); ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN DNA protection; regulation of transcription elongation by RNA polymerase II; transcription-coupled nucleotide-excision repair; PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; ASSOCIATED WITH abnormal base-excision repair; abnormal cerebellar cortex morphology; astrocytosis; ASSOCIATED WITH Cockayne syndrome B; middle cerebral artery infarction; transient cerebral ischemia; FOUND IN nuclear body (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; amphetamine | 16 | 7771311 | 7841895 | Rat | 310 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560481 | Esrp1 | epithelial splicing regulatory protein 1 | ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); branching involved in salivary gland morphogenesis (ortholog); epithelial tube branching involved in lung morphogenesis (ortholog); ASSOCIATED WITH autosomal recessive nonsyndr omic deafness 109 (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH amphetamine; bisphenol A; Cuprizon | 5 | 29224831 | 29279381 | Rat | 122 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309802 | Exo5 | exonuclease 5 | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (ortholog); single-stranded DNA 5'-3' DNA exonuclease activity (ortholog); INVOLVED IN interstrand cross-link repair (ortholog); FOUND IN cytosol (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetr achlorodibenzodioxine; acrylamide; amphetamine | 5 | 139779646 | 139782963 | Rat | 105 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1592539 | Exoc3l2 | exocyst complex component 3-like 2 | INVOLVED IN in utero embryonic development (ortholog); ASSOCIATED WITH BRAIN MALFORMATION RENAL SYNDROME (ortholog); Meckel syndrome (ortholog); FOUND IN exocyst (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amphe tamine | 1 | 88241784 | 88273352 | Rat | 55 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560201 | Fam114a1 | family with sequence similarity 114, member A1 | INVOLVED IN angiotensin-activated signaling pathway (ortholog); connective tissue replacement (ortholog); fibroblast activation (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amph '>amphetamine; bisphenol A | 14 | 43629349 | 43699800 | Rat | 109 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304927 | Fam135a | family with sequence similarity 135, member A | ASSOCIATED WITH infantile histiocytoid cardiomyopathy (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 9 | 33916449 | 33997140 | Rat | 70 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307966 | Fam171a2 | family with sequence similarity 171, member A2 | ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 87894049 | 87904213 | Rat | 56 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311484 | Fam234a | family with sequence similarity 234, member A | ASSOCIATED WITH basal cell carcinoma (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN cell surface (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,4-dinitrotoluene; amphetamine | 10 | 15736741 | 15768043 | Rat | 54 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560964 | Fam50a | family with sequence similarity 50, member A | INVOLVED IN regulation of RNA splicing (ortholog); ASSOCIATED WITH Armfield syndrome (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; at razine | X | 157246533 | 157253650 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1587477 | Fancg | FA complementation group G | INVOLVED IN DNA damage response (ortholog); mitochondrion organization (ortholog); ovarian follicle development (ortholog); ASSOCIATED WITH congenital myopathy 6 (ortholog); Fanconi anemia (ortholog); Fanconi anemia complementation group A (ortholog); FOUND IN chromatin (ortholog); Fanconi anaemia n uclear complex (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; acrylamide; amphetamine | 5 | 62027494 | 62037202 | Rat | 126 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310662 | Fbf1 | Fas binding factor 1 | INVOLVED IN apical junction assembly (ortholog); cilium assembly (ortholog); establishment of epithelial cell polarity (ortholog); FOUND IN apical junction complex (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amph le='font-weight:700;'>amphetamine | 10 | 101874661 | 101900497 | Rat | 81 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306887 | Fbxl5 | F-box and leucine-rich repeat protein 5 | ENCODES a protein that exhibits iron ion binding (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); multicellular organismal-level iron ion homeostasis (ortholog); positive regulation of protein catabolic process (ortholog); PARTICIPATES IN iron homeostasis pathway; ASSOCIATED WI TH prostate cancer (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); SCF ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 14 | 71517452 | 71559850 | Rat | 90 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308308 | Fbxo17 | F-box protein 17 | ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN ERAD pathway (inferred); glycoprotein catabolic process (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN SCF ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7, 8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 1 | 93129776 | 93151983 | Rat | 66 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306664 | Fbxo22 | F-box protein 22 | INVOLVED IN cellular response to starvation (ortholog); nucleocytoplasmic transport (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Tayoun-Maawali syndrome (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACT S WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; amphetamine | 8 | 64476034 | 64492063 | Rat | 99 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303082 | Fcar | Fc alpha receptor | ENCODES a protein that exhibits IgA binding (ortholog); IgA receptor activity (ortholog); INVOLVED IN cellular response to granulocyte macrophage colony-stimulating factor stimulus (ortholog); cellular response to interferon-alpha (ortholog); cellular response to interleukin-6 (ortholog); PARTICIPAT ES IN phagocytosis pathway; Staphylococcus aureus infection pathway; ASSOCIATED WITH granulomatosis with polyangiitis (ortholog); IgA glomerulonephritis (ortholog); renal fibrosis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH amphetamine; benzo[a]pyrene; bisphenol A | 1 | 78669119 | 78703223 | Rat | 52 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563939 | Fcrl6 | Fc receptor-like 6 | ENCODES a protein that exhibits MHC class II protein binding (ortholog); phosphatase binding (ortholog); protein phosphatase binding (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodi benzodioxine; amphetamine; bisphenol A | 13 | 87595058 | 87604657 | Rat | 33 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307000 | Fcsk | fucose kinase | ENCODES a protein that exhibits fucokinase activity (ortholog); INVOLVED IN response to dopamine; carbohydrate phosphorylation (ortholog); GDP-L-fucose salvage (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; A SSOCIATED WITH Congenital Disorder of Glycosylation with Defective Fucosylation (ortholog); Congenital Disorder of Glycosylation with Defective Fucosylation 2 (ortholog); Neurodevelopmental Disorders (ortholog); INTERACTS WITH 2,6-dinitrotoluene; acrylamide; amphetamine | 19 | 55743746 | 55783873 | Rat | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620130 | Fgf6 | fibroblast growth factor 6 | ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN cartilage condensation (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); myoblast differentiation (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; syndecan signaling pathwa y; melanoma pathway; ASSOCIATED WITH Acute Otitis Media (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); prostate carcinoma in situ (ortholog); FOUND IN sarcolemma; INTERACTS WITH ammonium chloride; bisphenol A; (S)-amphetamine (ortholog) | 4 | 161541089 | 161549624 | Rat | 71 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620448 | Fhit | fragile histidine triad diadenosine triphosphatase | ENCODES a protein that exhibits bis(5'-adenosyl)-triphosphatase activity; nickel cation binding; adenosine 5'-monophosphoramidase activity (ortholog); INVOLVED IN diadenosine triphosphate catabolic process; DNA replication (ortholog); intrinsic apoptotic signaling pathway by p53 class mediator (orth olog); PARTICIPATES IN non-small cell lung carcinoma pathway; purine metabolic pathway; small cell lung carcinoma pathway; ASSOCIATED WITH hepatocellular carcinoma; amenorrhea (ortholog); amphetamine abuse (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1-nitropropane; 2,4-diaminotoluene; 2,6-diaminotoluene | 15 | 16365401 | 17872901 | Rat | 228 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304816 | Fkbp15 | FKBP prolyl isomerase family member 15 | ENCODES a protein that exhibits actin binding (inferred); isomerase activity (inferred); peptidyl-prolyl cis-trans isomerase activity (inferred); INVOLVED IN endocytosis (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); genetic disease (ortholog); substa nce-related disorder (ortholog); FOUND IN actin cytoskeleton (ortholog); axon (ortholog); endosome (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 5 | 80766356 | 80830622 | Rat | 82 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309385 | Flywch1 | FLYWCH-type zinc finger 1 | ENCODES a protein that exhibits transcription coactivator binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Silver-Russell syndrome (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); pericentric heterochromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 10 | 13279232 | 13298955 | Rat | 87 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1583854 | Fmnl3 | formin-like 3 | ENCODES a protein that exhibits GTPase activating protein binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell migration (ortholog); filopodium assembly (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH alpha-Zearala nol; amphetamine; bisphenol A | 7 | 132333130 | 132384483 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308198 | Fosb | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription factor activity; double-stranded DNA binding; sequence-specific DNA binding; INVOLVED IN behavioral response to cocaine; cellular response to hormone stimulus; female pregnancy; ASSOCIATED WITH alcohol dependence; alcohol use disorder; amph style='font-weight:700;'>amphetamine abuse; FOUND IN cytosol; nucleus; nucleoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; (S)-amphetamine | 1 | 88082324 | 88089506 | Rat | 406 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562112 | Foxp3 | forkhead box P3 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN establishment of endothelial blood-brain barrier; negative regulation of defense response to virus; response to lipopolysaccharide; ASSOCIATED WITH asthma; bronchiolitis obliterans; Dysbiosis; FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; alpha-Zearalanol; amphetamine | X | 17580380 | 17601181 | Rat | 403 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311386 | Foxp4 | forkhead box P4 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN embryonic foregut morphogenesis (ortholog); heart development (ortholog); lung secretory cell differentiation (ortholog); ASSOCIATED WITH congestive heart failure (ortholog); Developmental Disabilities (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; alpha-Zearalanol; amphetamine | 9 | 20556270 | 20612967 | Rat | 114 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306763 | Foxred2 | FAD-dependent oxidoreductase domain containing 2 | ENCODES a protein that exhibits flavin adenine dinucleotide binding (ortholog); INVOLVED IN ERAD pathway (ortholog); FOUND IN endoplasmic reticulum lumen (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; amphetamine; bisphenol A | 7 | 111402322 | 111419056 | Rat | 74 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1584013 | Fpr2 | formyl peptide receptor 2 | ENCODES a protein that exhibits cargo receptor activity; RAGE receptor binding; amyloid-beta binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; astrocyte activation; cellular response to amyloid-beta; ASSOCIATED WITH dentin caries; Crohn's dise ase (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytoplasm; plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; amphetamine; bisphenol A | 1 | 67449637 | 67458272 | Rat | 137 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619954 | Fut4 | fucosyltransferase 4 | ENCODES a protein that exhibits alpha-(1->3)-fucosyltransferase activity; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity (ortholog); INVOLVED IN glycosphingolipid biosynthetic process (ortholog); Lewis x epitope biosynthetic process (ortholog); lymphocyte migration into lym ph node (ortholog); PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway; O-linked glycan biosynthetic pathway; ASSOCIATED WITH thrombosis (ortholog); FOUND IN cell periphery (ortholog); cell surface (ortholog); trans-Golgi network (ortholog); INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 19868178 | 19872139 | Rat | 145 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311085 | Gab1 | GRB2-associated binding protein 1 | ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN response to hepatocyte growth factor; angiogenesis (ortholog); cellular response to vascular endothelial growth factor stimulus (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; erythro poietin signaling pathway; fibroblast growth factor signaling pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 26 (ortholog); Experimental Liver Cirrhosis (ortholog); Helicobacter Infections (ortholog); FOUND IN cell cortex (ortholog); cell-cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; atrazine | 19 | 44035693 | 44143617 | Rat | 170 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62071 | Gap43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding; phosphatidylinositol phosphate binding; phosphatidylserine binding; INVOLVED IN nervous system development; regulation of postsynaptic specialization assembly; response to auditory stimulus; PARTICIPATES IN N-cadherin signaling pathway; ASSOCIATED WITH Experimental Seizures; Hearing Loss, Noise-Induced; middle cerebral artery infarction; FOUND IN GABA-ergic synapse; presynapse; axon (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 17alpha-ethynylestradiol | 11 | 71882131 | 71975799 | Rat | 273 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1591842 | Garem1 | GRB2 associated regulator of MAPK1 subtype 1 | ENCODES a protein that exhibits proline-rich region binding (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); epidermal growth factor receptor signaling pathway (ortholog); multicellular organism growth (ortholog); INTERACTS WITH 17beta-estradiol; amph 'font-weight:700;'>amphetamine; bisphenol A | 18 | 12695082 | 12860219 | Rat | 96 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564019 | Garnl3 | GTPase activating Rap/RanGAP domain-like 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of small GTPase mediated signal transduction (inferred); ASSOCIATED WITH intellectual disability (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol; amph hetamine | 3 | 36686388 | 36830011 | Rat | 72 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1586275 | Gemin5 | gem (nuclear organelle) associated protein 5 | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); ribosome binding (ortholog); RNA 7-methylguanosine cap binding (ortholog); INVOLVED IN regulation of translation (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH essential tremor (ortholog); genetic disease (ortholog); neurodevelopmental disorder with cerebellar atrophy and motor dysfunction (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear body (ortholog); INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; amphetamine | 10 | 42797975 | 42843356 | Rat | 135 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306765 | Ggn | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); gamete generation (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 93598076 | 93601598 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628871 | Gimap5 | GTPase, IMAP family member 5 | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN myeloid dendritic cell differentiation; negative regulation of apoptotic process; negative regulation of lipid catabolic process; ASSOCIATED WITH decreased body temperature; ASSOCIATED WITH lymphopenia ; type 1 diabetes mellitus; Noncirrhotic Portal Hypertension 2 (ortholog); FOUND IN endosome membrane (inferred); lysosomal membrane (inferred); mitochondrion (inferred); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 4 | 79025151 | 79031917 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1589721 | Gla | galactosidase, alpha | ENCODES a protein that exhibits alpha-galactosidase activity; galactoside binding; catalytic activity (ortholog); INVOLVED IN glycosphingolipid catabolic process; lipid storage; platelet activation; PARTICIPATES IN Fabry disease pathway; galactose metabolic pathway; galactosemia pathway; ASSOCIATED WITH abnormal circulating cytokine level; abnormal glycosphingolipid level; abnormal lens fiber morphology; ASSOCIATED WITH Fabry disease; lysosomal storage disease; Pain; FOUND IN cytoplasm (ortholog); extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | X | 102062497 | 102073915 | Rat | 266 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564821 | Gnptab | N-acetylglucosamine-1-phosphate transferase subunits alpha and beta | ENCODES a protein that exhibits UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity (ortholog); INVOLVED IN carbohydrate phosphorylation (ortholog); lysosome organization (ortholog); N-glycan processing to lysosome (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); genetic disease (ortholog); glycoproteinosis (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; cadmium dichloride | 7 | 24687923 | 24754821 | Rat | 106 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308935 | Gpatch1 | G patch domain containing 1 | ENCODES a protein that exhibits nucleic acid binding (inferred); INVOLVED IN mRNA processing (inferred); FOUND IN catalytic step 2 spliceosome (ortholog); INTERACTS WITH amphetamine; bisphenol A; Soman | 1 | 97062539 | 97111487 | Rat | 37 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619845 | Gper1 | G protein-coupled estrogen receptor 1 | ENCODES a protein that exhibits estradiol binding; G protein-coupled estrogen receptor activity; chromatin binding (ortholog); INVOLVED IN apoptotic chromosome condensation; cellular response to estradiol stimulus; cellular response to mineralocorticoid stimulus; PARTICIPATES IN epidermal growth fac tor/neuregulin signaling pathway; estrogen signaling pathway; serotonin signaling pathway; ASSOCIATED WITH abnormal free fatty acids level; decreased mean systemic arterial blood pressure; decreased pulse pressure; ASSOCIATED WITH Dysbiosis; Spinal Cord Injuries; Breast Neoplasms (ortholog); FOUND IN axon; axon terminus; cytoplasm; INTERACTS WITH (S)-amphetamine; 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol | 12 | 20331073 | 20336527 | Rat | 459 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311611 | Gpr25 | G protein-coupled receptor 25 | ENCODES a protein that exhibits C-X-C chemokine receptor activity (ortholog); G protein-coupled receptor activity (ortholog); INVOLVED IN chemokine-mediated signaling pathway (ortholog); leukocyte chemotaxis (ortholog); lymphocyte chemotaxis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; Cuprizon | 13 | 50264516 | 50266422 | Rat | 47 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306830 | Gpr33-ps1 | G protein-coupled receptor 33, pseudogene 1 | ASSOCIATED WITH Epidermolysis Bullosa Simplex 5D with Nail Dystrophy (ortholog); INTERACTS WITH amphetamine; bisphenol A; vinclozolin | 6 | 75209776 | 75210781 | Rat | 8 | description | gene, pseudo, INFERRED [RefSeq] |
| 619891 | Gpr83 | G protein-coupled receptor 83 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN feeding behavior (ortholog); G protein-coupled receptor signaling pathway (ortholog); neuropeptide signaling pathway (ortholog); FOUND IN cilium (ortholog); non-moti le cilium (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-amphetamine; (S)-nicotine; alpha-Zearalanol | 8 | 19974995 | 19985483 | Rat | 80 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563887 | Gprc5d | G protein-coupled receptor, class C, group 5, member D | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amph mphetamine; bisphenol A | 4 | 169674874 | 169686965 | Rat | 44 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309983 | Gramd4 | GRAM domain containing 4 | INVOLVED IN negative regulation of toll-like receptor 9 signaling pathway (ortholog); positive regulation of apoptotic process (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; atrazine | 7 | 119030225 | 119103875 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621531 | Gria1 | glutamate ionotropic receptor AMPA type subunit 1 | ENCODES a protein that exhibits adenylate cyclase binding; AMPA glutamate receptor activity; amyloid-beta binding; INVOLVED IN behavioral response to pain; cellular response to amine stimulus; cellular response to amino acid stimulus; PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling p athway; ephrin - ephrin receptor bidirectional signaling axis; amyotrophic lateral sclerosis pathway; ASSOCIATED WITH alcohol use disorder; alcohol withdrawal syndrome; amphetamine abuse; FOUND IN AMPA glutamate receptor complex; asymmetric synapse; cell surface; INTERACTS WITH (+)-pilocarpine; (-)-anisomycin; (S)-AMPA | 10 | 41710540 | 42030105 | Rat | 684 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 61862 | Gria2 | glutamate ionotropic receptor AMPA type subunit 2 | ENCODES a protein that exhibits AMPA glutamate receptor activity; amyloid-beta binding; cytoskeletal protein binding; INVOLVED IN AMPA glutamate receptor clustering; cellular response to amine stimulus; cellular response to brain-derived neurotrophic factor stimulus; PARTICIPATES IN N-cadherin signa ling pathway; amyotrophic lateral sclerosis pathway; glutamate signaling pathway; ASSOCIATED WITH abnormal channel response intensity; abnormal cued conditioning behavior; abnormal drug-induced reinstatement of an extinguished operant behavior for a drug reinforcer; ASSOCIATED WITH alcohol use disorder; amphetamine abuse; cannabis abuse; FOUND IN AMPA glutamate receptor complex; asymmetric synapse; axon; INTERACTS WITH (+)-pilocarpine; (-)-anisomycin; (S)-AMPA | 2 | 168247490 | 168367616 | Rat | 510 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 61986 | Grk6 | G protein-coupled receptor kinase 6 | ENCODES a protein that exhibits G protein-coupled receptor kinase activity; beta-adrenergic receptor kinase activity (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to lipopolysaccharide; desensitization of G protein-coupled receptor signaling pathway; negative regulati on of anion channel activity; PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; corticotropin-releasing hormone signaling pathway; dopamine signaling pathway via D1 family of receptors; ASSOCIATED WITH abnormal involuntary movement; abnormal locomotor behavior; ASSOCIATED WITH Diabetic Nephropathies; Drug-Induced Dyskinesia; Parkinson's disease; FOUND IN membrane (inferred); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 17 | 9182160 | 9198380 | Rat | 146 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2746 | Grm5 | glutamate metabotropic receptor 5 | ENCODES a protein that exhibits A2A adenosine receptor binding; glutamate receptor activity; protein tyrosine kinase activator activity; INVOLVED IN associative learning; chemical synaptic transmission; conditioned place preference; PARTICIPATES IN calcium/calcium-mediated signaling pathway; glutama te signaling pathway; Huntington's disease pathway; ASSOCIATED WITH alcohol dependence; alcohol use disorder; alcoholic neuropathy; FOUND IN astrocyte projection; dendrite; dendritic shaft; INTERACTS WITH (+)-pilocarpine; (S)-3,5-dihydroxyphenylglycine; (S)-amphetamine | 1 | 150722711 | 151297585 | Rat | 297 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619858 | Grm8 | glutamate metabotropic receptor 8 | ENCODES a protein that exhibits group III metabotropic glutamate receptor activity; G protein-coupled receptor activity (ortholog); glutamate receptor activity (ortholog); INVOLVED IN chemical synaptic transmission; detection of mechanical stimulus involved in sensory perception of pain; presynaptic modulation of chemical synaptic transmission; PARTICIPATES IN glutamate signaling pathway; ASSOCIATED WITH epilepsy; Experimental Seizures; Parkinsonism; FOUND IN GABA-ergic synapse; glutamatergic synapse; neuronal cell body; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 56771247 | 57696951 | Rat | 131 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308989 | Gsdmc | gasdermin C | ENCODES a protein that exhibits wide pore channel activity (ortholog); INVOLVED IN pyroptotic inflammatory response (ortholog); ASSOCIATED WITH lung adenocarcinoma (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; 1-nitropyrene (ortholog) | 7 | 97482713 | 97509985 | Rat | 39 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306546 | Gsg1 | germ cell associated 1 | ENCODES a protein that exhibits RNA polymerase binding (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 4 | 169822111 | 169838379 | Rat | 51 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311822 | Gstcd | glutathione S-transferase, C-terminal domain containing | INVOLVED IN respiratory system development (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amph 00;'>amphetamine | 2 | 224173764 | 224268743 | Rat | 60 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307435 | Gtf2ird2 | GTF2I repeat domain containing 2 | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN transition between fast and slow fiber (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 12 | 28134199 | 28179089 | Rat | 65 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2320502 | Gzmbl3 | Granzyme B-like 3 | ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); INTERACTS WITH amphetamine; trichloroethene | 15 | 34337656 | 34339888 | Rat | 4 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308088 | H2bc8 | H2B clustered histone 8 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); innate immune response in mucosa (ortholog); PARTICIPATES IN systemic lupus erythematosus pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); Prostatic Neoplasms (ortholog); FOUND IN extracellular exosome (ortholog); extracellular space (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; acetamide; amphetamine | 17 | 47404405 | 47405155 | Rat | 90 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595507 | Hacd1 | 3-hydroxyacyl-CoA dehydratase 1 | ENCODES a protein that exhibits 3-hydroxyacyl-CoA dehydratase activity (ortholog); enzyme binding (ortholog); hydroxyapatite binding (ortholog); INVOLVED IN cementum mineralization (ortholog); fatty acid elongation (ortholog); myotube differentiation (ortholog); PARTICIPATES IN unsaturated fatty aci d biosynthetic pathway; ASSOCIATED WITH Congenital Myopathy 11 (ortholog); congenital structural myopathy (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH aconitine; alpha-Zearalanol; amphetamine | 17 | 81992284 | 82014676 | Rat | 119 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619982 | Hdac7 | histone deacetylase 7 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN cellular response to mechanical stimulus; neuron apoptotic process; neuron differentiation; PARTICIPATES IN histone modification pathway; hypoxia inducible factor pathway; ASSOCIATED WITH alopecia areata (ortholog); colorectal cancer (ortholog); Huntington's disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 7 | 130803013 | 130841181 | Rat | 183 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562895 | Hdac8 | histone deacetylase 8 | ENCODES a protein that exhibits chromatin binding; deacetylase activity; transcription factor binding; INVOLVED IN cellular response to forskolin; cellular response to trichostatin A; negative regulation of gene expression; PARTICIPATES IN histone modification pathway; ASSOCIATED WITH amph ont-weight:700;'>amphetamine abuse; Cardiomegaly; hypertension; FOUND IN chromosome (inferred); cytoplasm (inferred); nucleus (inferred); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,4-dinitrotoluene; 2,6-dinitrotoluene | X | 71425240 | 71632865 | Rat | 156 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310748 | Hdac9 | histone deacetylase 9 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone deacetylase activity (ortholog); histone deacetylase binding (ortholog); INVOLVED IN neuron differentiation; response to amphetamine; cellular response to insulin stimul us (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH middle cerebral artery infarction; atherosclerosis (ortholog); Auriculocondylar Syndrome 4 (ortholog); FOUND IN cytoplasm (ortholog); histone methyltransferase complex (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 56489472 | 57351654 | Rat | 186 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308267 | Heatr3 | HEAT repeat containing 3 | INVOLVED IN erythrocyte maturation (ortholog); protein import into nucleus (ortholog); ribosomal large subunit biogenesis (ortholog); ASSOCIATED WITH Diamond-Blackfan anemia (ortholog); Diamond-Blackfan anemia 1 (ortholog); Diamond-Blackfan Anemia 21 (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; alpha-Zearalanol; amphetamine | 19 | 35065915 | 35103779 | Rat | 82 | description | gene, protein-coding, MODEL [RefSeq] |
| 1564641 | Heg1 | heart development protein with EGF-like domains 1 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cardiac atrium morphogenesis (ortholog); cardiac muscle tissue growth (ortholog); cell-cell junction organization (ortholog); FOUND IN cell surface (ortholog); cell-cell junction (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrolein; amphetamine | 11 | 80512096 | 80600150 | Rat | 147 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560103 | Helb | DNA helicase B | ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); DNA helicase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN DNA damage response (ortholog); DNA replication (ortholog); DNA replication, synthesis of primer (ortholog); FOUND IN cytoplasm (orthol og); cytosol (ortholog); DNA replication factor A complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 7 | 57474115 | 57502221 | Rat | 117 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560216 | Helq | helicase, POLQ-like | ENCODES a protein that exhibits single-stranded 3'-5' DNA helicase activity (ortholog); INVOLVED IN DNA double-strand break processing involved in repair via single-strand annealing (ortholog); double-strand break repair via alternative nonhomologous end joining (ortholog); double-strand break repai r via homologous recombination (ortholog); FOUND IN nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH amphetamine; bisphenol A; copper atom | 14 | 9122978 | 9167310 | Rat | 100 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307049 | Helz | helicase with zinc finger | ENCODES a protein that exhibits CCR4-NOT complex binding (ortholog); INVOLVED IN negative regulation of translation (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (ortholog) ; ASSOCIATED WITH pervasive developmental disorder (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amphetamine | 10 | 92979039 | 93144868 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309691 | Higd2a | HIG1 hypoxia inducible domain family, member 2A | INVOLVED IN mitochondrial respirasome assembly (ortholog); negative regulation of apoptotic process (ortholog); response to quercetin (ortholog); ASSOCIATED WITH Liver Neoplasms (ortholog); pre-malignant neoplasm (ortholog); FOUND IN mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7 ,8-tetrachlorodibenzodioxine; amphetamine; bis(2-ethylhexyl) phthalate | 17 | 10026961 | 10027885 | Rat | 56 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565360 | Hlcs | holocarboxylase synthetase | ENCODES a protein that exhibits biotin--[biotin carboxyl-carrier protein] ligase activity; identical protein binding; biotin binding (ortholog); INVOLVED IN response to biotin; biotin metabolic process (ortholog); post-translational protein modification (ortholog); PARTICIPATES IN biotin metabolic p athway; biotinidase deficiency pathway; holocarboxylase synthetase deficiency pathway; ASSOCIATED WITH genetic disease (ortholog); holocarboxylase synthetase deficiency (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); nuclear lamina (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 11 | 46925491 | 47123111 | Rat | 133 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306787 | Hmbox1 | homeobox containing 1 | ENCODES a protein that exhibits double-stranded telomeric DNA binding (ortholog); identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); telomere maintenance via telomerase (ortholog); FOUND IN chromosome, telomeric region (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 15 | 43243503 | 43376011 | Rat | 124 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620626 | Hoxc6 | homeo box C6 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic skeletal system development (o rtholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH amphetamine; bisphenol A; boric acid | 7 | 136013679 | 136051601 | Rat | 92 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 11422907 | Hs3st4 | heparan sulfate-glucosamine 3-sulfotransferase 4 | ENCODES a protein that exhibits sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); FOUND IN Golgi apparatus (inferred); IN TERACTS WITH methoxychlor; aflatoxin B1 (ortholog); arsenite(3-) (ortholog) | 1 | 187970127 | 188375869 | Rat | 27 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309218 | Hs6st1 | heparan sulfate 6-O-sulfotransferase 1 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (ortholog); INVOLVED IN angiogenesis (ortholog); heparan sulfate proteoglycan biosynthetic process (ortholog); labyrinthine layer blood vessel development (ortholog); PARTICIPATES IN heparan sulfate biosynthetic pathway; ASS OCIATED WITH hypogonadotropic hypogonadism 15 with or without anosmia (ortholog); hypogonadotropic hypogonadism 7 with or without anosmia (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; amphetamine | 9 | 45779402 | 45818583 | Rat | 100 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61818 | Htr3a | 5-hydroxytryptamine receptor 3A | ENCODES a protein that exhibits serotonin-gated monoatomic cation channel activity; identical protein binding (ortholog); ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ortholog); INVOLVED IN behavioral response to ethanol; cellular response to growth factor stimulus; positive regulation of ion transmembrane transporter activity; ASSOCIATED WITH alcohol dependence; alcohol use disorder (ortholog); amphetamine abuse (ortholog); FOUND IN axon; glutamatergic synapse; neuronal cell body; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-bromopropane; 6-propyl-2-thiouracil | 8 | 58138514 | 58150960 | Rat | 211 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2851 | Htr5a | 5-hydroxytryptamine receptor 5A | ENCODES a protein that exhibits G protein-coupled serotonin receptor activity; Gi/o-coupled serotonin receptor activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; hippocampus development; response to estradiol; PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); intracranial hypertension (ortholog); prostate cancer (ortholog); FOUND IN dendrite; perikaryon; postsynaptic specialization membrane; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; alendronic acid | 4 | 8178802 | 8188485 | Rat | 75 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62044 | Htr6 | 5-hydroxytryptamine receptor 6 | ENCODES a protein that exhibits G protein-coupled serotonin receptor activity; INVOLVED IN G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; learning; long-term synaptic potentiation; PARTICIPATES IN serotonin signaling pathway via receptors engaging G alph as protein family; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amphetamine abuse (ortholog); Memory Disorders (ortholog); FOUND IN dendrite; cilium (ortholog); plasma membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride | 5 | 156579901 | 156595147 | Rat | 116 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1585038 | Ice2 | interactor of little elongation complex ELL subunit 2 | INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); snRNA transcription by RNA polymerase II (ortholog); snRNA transcription by RNA polymerase III (ortholog); ASSOCIATED WITH Cocaine-Related Disorders (ortholog); Paranoid Disorders (ortholog); FOUND IN Cajal body (orth olog); euchromatin (ortholog); histone locus body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 78921962 | 78965983 | Rat | 112 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307392 | Ift43 | intraflagellar transport 43 | INVOLVED IN cilium assembly (ortholog); intraciliary retrograde transport (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); connective tissue disease (ortholog); cranioectodermal dysplasia (ortholog); FOUND IN centriole (ortholog); cilium (ortholog); intercellular bridge (ortho log); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 6 | 111460689 | 111537224 | Rat | 78 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305947 | Ift57 | intraflagellar transport 57 | INVOLVED IN apoptotic process (ortholog); heart looping (ortholog); left/right pattern formation (ortholog); PARTICIPATES IN Huntington's disease pathway; ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Huntington's disease (ortholog); orofaciodigital syndrome XVIII (ortholog); FOUND IN axoneme (o rtholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A | 11 | 64528349 | 64593545 | Rat | 117 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309717 | Ift88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (ortholog); INVOLVED IN response to silicon dioxide; animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH silicosis; asphyxiating thoracic dystrophy (ort holog); autosomal recessive polycystic kidney disease (ortholog); FOUND IN outer acrosomal membrane; trans-Golgi network; acrosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 15 | 35685678 | 35786875 | Rat | 171 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1592119 | Igsf7 | immunoglobulin superfamily, member 7 | INVOLVED IN immune system process (inferred); FOUND IN plasma membrane (inferred); INTERACTS WITH 3,4-methylenedioxymethamphetamine; amphetamine; methylmercury chloride | 10 | 100652768 | 100660499 | Rat | 6 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308686 | Ikzf2 | IKAROS family zinc finger 2 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); identical protein binding (ortholog); INVOLVED IN cochlear outer hair cell electromotile response (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); sensory perception of sound (ortho log); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); adult T-cell leukemia/lymphoma (ortholog); COVID-19 (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17beta-estradiol; alpha-Zearalanol; amphetamine | 9 | 78495670 | 78640896 | Rat | 120 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1303169 | Il22ra2 | interleukin 22 receptor subunit alpha 2 | ENCODES a protein that exhibits interleukin-22 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH multisystem inflammatory syndrome in children (ortholog); Mycoplasma pneumoniae pneumonia (ortholog); FOUND IN cytosol (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 1 | 16172238 | 16228009 | Rat | 63 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304831 | Il4i1 | interleukin 4 induced 1 | ENCODES a protein that exhibits L-amino-acid oxidase activity (ortholog); INVOLVED IN aromatic amino acid metabolic process (ortholog); L-phenylalanine catabolic process (ortholog); L-tryptophan catabolic process (ortholog); PARTICIPATES IN Canavan disease pathway; glycine N-methyltransferase defici ency pathway; homocystinuria pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); Inflammation (ortholog); FOUND IN acrosomal vesicle (ortholog); extracellular region (ortholog); immunological synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 1 | 104435540 | 104461049 | Rat | 105 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2907 | Il9r | interleukin 9 receptor | ENCODES a protein that exhibits interleukin-9 binding; interleukin-9 receptor activity; INVOLVED IN positive regulation of cell growth; B cell differentiation (ortholog); B cell proliferation (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH asthma (ortholog); Brain Injuries (ortholog); cystic fibrosis (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 10 | 15936156 | 15947613 | Rat | 76 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2912 | Inha | inhibin subunit alpha | ENCODES a protein that exhibits inhibin binding; protein-containing complex binding; protein sequestering activity (ortholog); INVOLVED IN male gonad development; negative regulation of follicle-stimulating hormone secretion; ovarian follicle development; ASSOCIATED WITH abnormal estrous cycle; incr eased litter size; ASSOCIATED WITH Experimental Autoimmune Orchitis; Leydig cell tumor; dysgerminoma (ortholog); FOUND IN extracellular space; inhibin A complex; inhibin B complex; INTERACTS WITH (S)-amphetamine; (S)-colchicine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane | 9 | 84443109 | 84446010 | Rat | 193 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310969 | Ino80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); ATP-dependent activity, acting on DNA (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to ionizing radiation (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 famil y mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN cytosol (ortholog); Ino80 complex (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; amphetamine | 3 | 126822280 | 126919532 | Rat | 156 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1304808 | Ino80d | INO80 complex subunit D | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8- Tetrachlorodibenzofuran; amphetamine | 9 | 71940941 | 72007879 | Rat | 90 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 7747960 | Insl5 | insulin like 5 | INVOLVED IN positive regulation of feeding behavior (ortholog); INTERACTS WITH (S)-amphetamine (ortholog); 1,2-dimethylhydrazine (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 5 | 122998320 | 123016348 | Rat | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 1311133 | Ipo11 | importin 11 | ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN intracellular protein transport (inferred); protein transport (inferred); FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 2 | 39903316 | 40076485 | Rat | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 1593688 | Ipo8 | importin 8 | ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN intracellular protein transport (inferred); protein transport (inferred); ASSOCIATED WITH congenital contractural arachnodactyly (ortholog); genetic disease (ortholog); Marfan syndrome (ortholog); FOUND IN cytoplasm (inferr ed); nucleus (inferred); INTERACTS WITH amphetamine; (1->4)-beta-D-glucan (ortholog); 1,2-dimethylhydrazine (ortholog) | 4 | 183460583 | 183529259 | Rat | 74 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 71075 | Itgad | integrin subunit alpha D | ENCODES a protein that exhibits protein-containing complex binding; cell adhesion receptor activity (ortholog); INVOLVED IN activated T cell proliferation (ortholog); cell-cell adhesion mediated by integrin (ortholog); heterotypic cell-cell adhesion (ortholog); PARTICIPATES IN integrin mediated sign aling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN integrin alphaD-beta2 complex (ortholog); plasma membrane (ortholog); INTERACTS WITH acetamide; ammonium chloride; amphetamine | 1 | 192190204 | 192218864 | Rat | 63 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2926 | Itgam | integrin subunit alpha M | ENCODES a protein that exhibits protein-containing complex binding; cargo receptor activity (ortholog); cell adhesion receptor activity (ortholog); INVOLVED IN heterotypic cell-cell adhesion; response to amphetamine; response to curcumin; PARTICIPATES IN integri n mediated signaling pathway; Entamoebiasis pathway; Leishmaniasis pathway; ASSOCIATED WITH Acute Lung Injury; Brain Death; brain ischemia; FOUND IN cell surface; external side of plasma membrane (ortholog); extracellular space (ortholog); INTERACTS WITH (R,R,R)-alpha-tocopherol; 1-naphthyl isothiocyanate; 17beta-estradiol | 1 | 192089496 | 192139947 | Rat | 529 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309503 | Itm2c | integral membrane protein 2C | ENCODES a protein that exhibits amyloid-beta binding (ortholog); ATP binding (ortholog); INVOLVED IN negative regulation of neuron projection development (ortholog); neuron differentiation (ortholog); positive regulation of extrinsic apoptotic signaling pathway (ortholog); FOUND IN Golgi apparatus ( ortholog); lysosome (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; amphetamine | 9 | 93993922 | 94007737 | Rat | 112 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309152 | Jade2 | jade family PHD finger 2 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); histone H4K16 acetyltransferase activity (ortholog); INVOLVED IN neuron projection extension (ortholog); positive regulation of neurogenesis (ortholog); protein a utoubiquitination (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 10 | 36576187 | 36625129 | Rat | 120 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2940 | Jak3 | Janus kinase 3 | ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway; positive regulation of activated T cell proliferation; positive regulation of calcium ion transport; PARTICIPATES IN altered Jak-Stat signaling pathway; interleukin-2 signaling pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Colonic Neoplasms; Experimental Arthritis; Experimental Autoimmune Encephalomyelitis; FOUND IN extrinsic component of cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bis(2-ethylhexyl) phthalate | 16 | 18418807 | 18432515 | Rat | 250 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562401 | Jakmip1 | janus kinase and microtubule interacting protein 1 | ENCODES a protein that exhibits GABA receptor binding (ortholog); kinesin binding (ortholog); RNA binding (ortholog); INVOLVED IN cognition (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); intellectual disability (ortholog); FOUND IN microtubule cytoskel eton; membrane (ortholog); ribonucleoprotein complex (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A | 14 | 77871034 | 77991566 | Rat | 82 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 708458 | Jmjd1c | jumonji domain containing 1C | ENCODES a protein that exhibits histone H3K9 demethylase activity (ortholog); protein demethylase activity (ortholog); INVOLVED IN epithelial cell morphogenesis (ortholog); lipid biosynthetic process (ortholog); maintenance of cell number (ortholog); PARTICIPATES IN histone modification pathway; ASS OCIATED WITH adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17beta-estradiol; ammonium chloride; amphetamine | 20 | 21330990 | 21508580 | Rat | 146 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1585601 | Jmy | junction mediating and regulatory protein, p53 cofactor | ENCODES a protein that exhibits microtubule binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN 'de novo' actin filament nucleation (ortholog); actin polymerization-dependent cell motility (ortholog); Arp2/3 complex-mediated actin nucleation (ortholog); FOUND IN autophagos ome membrane (ortholog); cell leading edge (ortholog); cytoplasmic vesicle (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 4,4'-diaminodiphenylmethane; amphetamine | 2 | 26401047 | 26465959 | Rat | 127 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306316 | Jrk | Jrk helix-turn-helix protein | ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN positive regulation of canonical Wnt signaling pathway (ortholog); ASSOCIATED WITH childhood absence epilepsy (ortholog); generalized epilepsy (ortholog); juvenile myoclonic epilepsy (ortholog); FOUND IN cytoplasm (ortholog); nucle us (ortholog); ribonucleoprotein complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 7 | 108479646 | 108484329 | Rat | 65 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2945 | Jund | JunD proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; double-stranded DNA binding; INVOLVED IN cellular response to fatty acid; cellular response to hypoxia; cellular response to polyamine macromolecule; P ARTICIPATES IN platelet-derived growth factor signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH crescentic glomerulonephritis; Dyskinesias; renal carcinoma; FOUND IN nucleus; protein-containing complex; protein-DNA complex; INTERACTS WITH (S)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 18768093 | 18769771 | Rat | 363 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1307242 | Kat2a | lysine acetyltransferase 2A | ENCODES a protein that exhibits chromatin binding; protein phosphatase binding; acetyltransferase activity (ortholog); INVOLVED IN alpha-tubulin acetylation; cellular response to nerve growth factor stimulus; cellular response to tumor necrosis factor; PARTICIPATES IN histone modification pathway; p 53 signaling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH hepatitis B (ortholog); lung non-small cell carcinoma (ortholog); neural tube defect (ortholog); FOUND IN chromatin; ATAC complex (ortholog); centrosome (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; amphetamine; bisphenol A | 10 | 86132535 | 86140877 | Rat | 245 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563576 | Kbtbd11 | kelch repeat and BTB domain containing 11 | ASSOCIATED WITH hepatocellular carcinoma (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bis(2-ethylhexyl) phthalate | 16 | 81318596 | 81340334 | Rat | 100 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2957 | Kcnj1 | potassium inwardly-rectifying channel, subfamily J, member 1 | ENCODES a protein that exhibits ATP binding; ATP-activated inward rectifier potassium channel activity; inward rectifier potassium channel activity; INVOLVED IN cellular response to magnesium ion; negative regulation of apoptotic process; potassium ion import across plasma membrane; PARTICIPATES IN aldosterone signaling pathway; ASSOCIATED WITH decreased body weight; decreased circulating bicarbonate level; decreased susceptibility to hypertension; ASSOCIATED WITH nephrotic syndrome; Bartter disease (ortholog); Bartter disease type 2 (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-amphetamine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 8 | 39014822 | 39066716 | Rat | 132 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307125 | Kctd11 | potassium channel tetramerization domain containing 11 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cell differentiation (ortholog); negative regulation of neuroblast proliferation (ortholog); negative regulation of smoothened signaling pathway (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrach lorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 10 | 55101292 | 55103455 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308211 | Klhdc1 | kelch domain containing 1 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (ortholog); FOUND IN Cul5-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTER ACTS WITH 6-propyl-2-thiouracil; acetamide; amphetamine | 6 | 93406226 | 93501475 | Rat | 60 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561366 | Klhl36 | kelch-like family member 36 | ENCODES a protein that exhibits cullin family protein binding (ortholog); INVOLVED IN protein ubiquitination (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 19 | 64830218 | 64851251 | Rat | 45 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304685 | Klhl8 | kelch-like family member 8 | INVOLVED IN protein ubiquitination (ortholog); ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH catecholaminergic polymorphic ventricular tachycardia (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,6-dinitrotoluene ; acetamide; amphetamine | 14 | 6112472 | 6158001 | Rat | 50 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2975 | Klrb1b | killer cell lectin-like receptor subfamily B member 1B | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); signaling receptor activity (ortholog); INVOLVED IN negative regulation of natural killer cell mediated cytotoxicity (ortholog); PARTICIPATES IN malaria pathway; FOUND IN external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH ammonium chloride; amphetamine; decabromodiphenyl ether | 4 | 163634357 | 163647629 | Rat | 34 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2324324 | Kmt2d | lysine methyltransferase 2D | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); histone H3K4 methyltransferase activity (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN heterochromatin formation (ortholog); in utero embryonic develo pment (ortholog); oocyte growth (ortholog); PARTICIPATES IN histone modification pathway; lysine degradation pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 26 (ortholog); FOUND IN MLL3/4 complex (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; amphetamine | 7 | 131859696 | 131901032 | Rat | 202 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1584538 | Krt71 | keratin 71 | INVOLVED IN hair follicle morphogenesis (ortholog); intermediate filament organization (ortholog); ASSOCIATED WITH abnormal hair cuticle; dilated hair follicle; progressive hair loss; ASSOCIATED WITH alopecia; Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); FOUND IN keratin filament (orth olog); INTERACTS WITH alpha-Zearalanol; amphetamine; paracetamol | 7 | 134752240 | 134778765 | Rat | 53 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308889 | Lama2 | laminin subunit alpha 2 | ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN Schwann cell differentiation; axon guidance (ortholog); positive regulation of synaptic transmission, cholinergic (ortholog); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; dilated cardiomyopathy pathway; ASSOCIATED WITH renovascular hypertension; Thyroid Neoplasms; autosomal recessive limb-girdle muscular dystrophy type 23 (ortholog); FOUND IN basement membrane; dendritic spine; neuromuscular junction (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 1 | 19492126 | 20140056 | Rat | 182 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307133 | Lamtor3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); kinase activator activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); intracellular protein localization (ortholog); positive regulation of M APK cascade (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN FNIP-folliculin RagC/D GAP (ortholog); late endosome (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,6-dinitrotoluene; amphetamine | 2 | 229084795 | 229097028 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308895 | Large1 | LARGE xylosyl- and glucuronyltransferase 1 | ENCODES a protein that exhibits glucuronosyltransferase activity (ortholog); glycosyltransferase activity (ortholog); hexosyltransferase activity (ortholog); INVOLVED IN acetylcholine receptor signaling pathway (ortholog); astrocyte differentiation (ortholog); basement membrane organization (ortholo g); ASSOCIATED WITH amphetamine abuse (ortholog); congenital muscular dystrophy (ortholog); congenital muscular dystrophy-dystroglycanopathy type A1 (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); neuromuscular junction (ortholog); INTERACTS WITH (+)-schisandrin B; 3,3',4,4',5-pentachlorobiphenyl; acetamide | 19 | 11609004 | 12057174 | Rat | 224 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563417 | Ldlrap1 | low density lipoprotein receptor adaptor protein 1 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); AP-1 adaptor complex binding (ortholog); AP-2 adaptor complex binding (ortholog); INVOLVED IN amyloid precursor protein metabolic process (ortholog); cellular response to cytokine stimulus (ortholog); cholesterol homeostasis (ortholog) ; PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); familial hypercholesterolemia (ortholog); Hypercholesterolemia (ortholog); FOUND IN axon; basal plasma membrane (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 5 | 152239296 | 152262290 | Rat | 141 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561867 | Lefty1 | left right determination factor 1 | ENCODES a protein that exhibits nodal binding (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); cell migration involved in gastrulation (ortholog); determination of left/right symmetry (ortholog); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH myocardial infarction (ortholog); Tubulointerstitial Fibrosis (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH amphetamine; bisphenol A; cadmium dichloride | 13 | 95188091 | 95191488 | Rat | 109 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307168 | Leprotl1 | leptin receptor overlapping transcript-like 1 | ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,4-dinitrotoluene; amphetamine; bisphenol A | 16 | 64744148 | 64756776 | Rat | 72 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359678 | Letm1 | leucine zipper and EF-hand containing transmembrane protein 1 | ENCODES a protein that exhibits calcium:proton antiporter activity (ortholog); INVOLVED IN calcium export from the mitochondrion (ortholog); calcium ion transport (ortholog); cristae formation (ortholog); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); Developmental Disabilities (ortholog); E pendymomas (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 14 | 81167268 | 81206776 | Rat | 166 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310773 | Lingo2 | leucine rich repeat and Ig domain containing 2 | INVOLVED IN positive regulation of synapse assembly (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); Liver Neoplasms (ortholog); megacolon (ortholog); FOUND IN glutamatergic synapse; synaptic membrane; INTERACTS WITH bisphenol A; cadmium dichloride; Cup rizon | 5 | 55166250 | 56488672 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1592209 | Lingo3 | leucine rich repeat and Ig domain containing 3 | ASSOCIATED WITH myoepithelioma (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 7 | 9519252 | 9530675 | Rat | 35 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308792 | Lins1 | lines homolog 1 | INVOLVED IN cognition (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal recessive intellectual developmental disorder 27 (ortholog); genetic disease (ortholog); INTERACTS WITH amphetamine; bisphenol A; endosulfan | 1 | 129677815 | 129705399 | Rat | 40 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1588534 | Lpin3 | lipin 3 | ENCODES a protein that exhibits phosphatidate phosphatase activity (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 3 | 169953479 | 169978034 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306788 | Lrig1 | leucine-rich repeats and immunoglobulin-like domains 1 | INVOLVED IN hair cycle process (ortholog); innervation (ortholog); otolith morphogenesis (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; amphetamine | 4 | 128687723 | 128788219 | Rat | 141 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359442 | Lrwd1 | leucine-rich repeats and WD repeat domain containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); histone H3K27me3 reader activity (ortholog); methyl-CpG binding (ortholog); INVOLVED IN chromatin organization (ortholog); establishment of protein localization to chromatin (ortholog); FOUND IN chromosome, telomeric region (ortholog); ki netochore (ortholog); nuclear origin of replication recognition complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 12 | 26166648 | 26179689 | Rat | 88 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563798 | Lsm14b | LSM family member 14B | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN maternal mRNA clearance (ortholog); meiotic cell cycle process involved in oocyte maturation (ortholog); membraneless organelle assembly (ortholog); FOUND IN cytoplasmic ribonucleoprotein granule (ortholog); INTERACTS WITH amph le='font-weight:700;'>amphetamine; Brodifacoum; poly(I:C) | 3 | 187503251 | 187514041 | Rat | 64 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359240 | Ly49si2 | immunoreceptor Ly49si2 | ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN cell adhesion (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine | 4 | 165358092 | 165410591 | Rat | 15 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306132 | Ly6d | lymphocyte antigen 6 family member D | INVOLVED IN lymphocyte differentiation (ortholog); response to stilbenoid (ortholog); FOUND IN cell surface (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 7 | 108532207 | 108533943 | Rat | 116 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303064 | Ly6g6d | lymphocyte antigen 6 family member G6D | ENCODES a protein that exhibits acetylcholine receptor inhibitor activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetylcholine receptor signaling pathway (ortholog); FOUND IN external side of plasma membrane (ortholog); protein-containing complex (ortholog); INTERACTS WITH ... (more) an style='font-weight:700;'>amphetamine; bisphenol A; C60 fullerene | 20 | 3746630 | 3757036 | Rat | 45 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1303333 | Ly6g6f | lymphocyte antigen 6 family member G6F | FOUND IN plasma membrane (inferred); side of membrane (inferred); INTERACTS WITH amphetamine; bis(2-ethylhexyl) phthalate; bisphenol A | 20 | 3742116 | 3746984 | Rat | 13 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3036 | Mak | male germ cell-associated kinase | ENCODES a protein that exhibits protein kinase activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN negative regulation of non-motile cilium assembly (ortholog); photoreceptor cell maintenance (ortholog); protein autophosphorylation (ortholog); ASSOCIATED WITH fundus dystr ophy (ortholog); genetic disease (ortholog); retinitis pigmentosa (ortholog); FOUND IN axoneme (ortholog); centrosome (ortholog); ciliary tip (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; amphetamine | 17 | 23889417 | 23936857 | Rat | 160 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306936 | Malsu1 | mitochondrial assembly of ribosomal large subunit 1 | ENCODES a protein that exhibits mitochondrial large ribosomal subunit binding (ortholog); INVOLVED IN mitochondrial large ribosomal subunit assembly (ortholog); negative regulation of mitochondrial translation (ortholog); ribosomal large subunit biogenesis (ortholog); FOUND IN mitochondrion (ortholo g); INTERACTS WITH acetamide; amphetamine; bisphenol A | 4 | 79381963 | 79390786 | Rat | 56 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61890 | Map2k5 | mitogen activated protein kinase kinase 5 | ENCODES a protein that exhibits ATP binding; protein kinase activity; MAP kinase kinase activity (ortholog); INVOLVED IN cellular response to growth factor stimulus; ERK5 cascade; MAPK cascade; PARTICIPATES IN Erk5 MAPK signaling pathway; altered Erk5 MAPK signaling pathway; mitogen activated protei n kinase signaling pathway; ASSOCIATED WITH amphetamine abuse (ortholog); Body Weight (ortholog); Cardiomegaly (ortholog); FOUND IN spindle (ortholog); INTERACTS WITH 1,1-dichloroethene; 1,2,4-trimethylbenzene; ammonium chloride | 8 | 72520616 | 72748395 | Rat | 182 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304575 | Map3k3 | mitogen activated protein kinase kinase kinase 3 | ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN blood vessel development (ortholog); intracellular signal transduction (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathwa y; Erk5 MAPK signaling pathway; interleukin-1 signaling pathway; ASSOCIATED WITH Cerebral Cavernous Malformation 5 (ortholog); Esophageal Neoplasms (ortholog); verrucous keratotic hemangioma (ortholog); INTERACTS WITH 2,6-dinitrotoluene; amphetamine; bisphenol A | 10 | 91519976 | 91588651 | Rat | 103 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307578 | Mapkbp1 | mitogen activated protein kinase binding protein 1 | INVOLVED IN negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of defense response to bacterium (ortholog); negative regulation of interleukin-8 production (ortholog); ASSOCIATED WITH genetic disease (ortholog); nephronophthisis 20 (ortholog); FOUND IN cyt oplasm (ortholog); mitotic spindle pole (ortholog); nucleolus (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; amphetamine | 3 | 127401612 | 127452152 | Rat | 80 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 67380 | Mbl2 | mannose binding lectin 2 | ENCODES a protein that exhibits calcium ion binding; D-mannose binding; galactose binding; INVOLVED IN positive regulation of complement activation; positive regulation of protein processing; antiviral innate immune response (ortholog); PARTICIPATES IN lectin complement pathway; coagulation cascade pathway; complement system pathway; ASSOCIATED WITH Yin Deficiency; adult respiratory distress syndrome (ortholog); allergic bronchopulmonary aspergillosis (ortholog); FOUND IN extracellular space; protein-containing complex; symbiont cell surface (ortholog); INTERACTS WITH (+)-schisandrin B; (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 237429873 | 237465567 | Rat | 337 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566335 | Mboat4 | membrane bound ghrelin O-acyltransferase MBOAT4 | ENCODES a protein that exhibits serine O-acyltransferase activity; acyltransferase activity, transferring groups other than amino-acyl groups (ortholog); INVOLVED IN peptidyl-serine octanoylation; protein acylation (ortholog); protein decanoylation (ortholog); FOUND IN endoplasmic reticulum (ortholo g); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH amphetamine; bisphenol A; copper atom | 16 | 64765151 | 64780545 | Rat | 56 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306945 | Mboat7 | membrane bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7 | ENCODES a protein that exhibits lysophospholipid acyltransferase activity (ortholog); O-acyltransferase activity (ortholog); INVOLVED IN layer formation in cerebral cortex (ortholog); phosphatidylcholine acyl-chain remodeling (ortholog); phosphatidylinositol acyl-chain remodeling (ortholog); ASSOCIA TED WITH alcoholic liver cirrhosis (ortholog); autosomal recessive intellectual developmental disorder 57 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog); mitochondria-associated endoplasmic reticulum membrane contact site (ortholog); INTERACTS WITH 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol; amphetamine | 1 | 74440618 | 74454896 | Rat | 125 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306698 | Mcat | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (ortholog); RNA folding chaperone (ortholog); INVOLVED IN fatty acid biosynthetic process (ortholog); mitochondrial small ribosomal subunit assembly (ortholog); PARTICIPATES IN fatty acid biosynthetic pathway; ASSOC IATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; amphetamine | 7 | 116573632 | 116585767 | Rat | 73 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560642 | Mcph1 | microcephalin 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN bone development (ortholog); cerebral cortex development (ortholog); establishment of mitotic spindle orientation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH breast cancer (ortholog); Brea st Neoplasms (ortholog); Developmental Disabilities (ortholog); FOUND IN centrosome (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 16 | 77724251 | 77926773 | Rat | 114 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562967 | Mctp2 | multiple C2 and transmembrane domain containing 2 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); ASSOCIATED WITH genetic disease (ortholog); tetralogy of Fallot (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); nucleoplasm (ortholog); INTERACTS WITH acetamide; alpha-Zea ralanol; amphetamine | 1 | 135179845 | 135412798 | Rat | 86 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559552 | Med1 | mediator complex subunit 1 | ENCODES a protein that exhibits chromatin binding; chromatin DNA binding; general transcription initiation factor binding; INVOLVED IN cellular response to thyroid hormone stimulus; positive regulation of transcription by RNA polymerase II; protein ubiquitination; PARTICIPATES IN cortisol signaling pathway; estrogen signaling pathway; RNA polymerase II transcription pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN chromatin; protein-DNA complex; ubiquitin ligase complex; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 10 | 83641851 | 83685560 | Rat | 342 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1585896 | Med12 | mediator complex subunit 12 | ENCODES a protein that exhibits ubiquitin protein ligase activity; chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); INVOLVED IN protein ubiquitination; axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); angiosarcoma (ortholog); FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | X | 70444615 | 70467780 | Rat | 156 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308532 | Meis3 | Meis homeobox 3 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of apoptotic signaling pathway (ortholog); positive regulation of phosphatidyli nositol 3-kinase/protein kinase B signal transduction (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 85986602 | 86000873 | Rat | 81 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307413 | Metap1d | methionyl aminopeptidase type 1D (mitochondrial) | ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); initiator methionyl aminopeptidase activity (inferred); INVOLVED IN post-translational protein modification (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH aflatoxin B1; amph -weight:700;'>amphetamine; atrazine | 3 | 76687149 | 76759681 | Rat | 56 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311526 | Mettl13 | methyltransferase 13, eEF1A N-terminus and K55 | ENCODES a protein that exhibits protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN methylation (inferred); ASSOCIATED WITH Nonsyndromic Deafness, Modifier 1 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH amph ht:700;'>amphetamine; bisphenol A; cadmium dichloride | 13 | 77419393 | 77433228 | Rat | 57 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306451 | Mettl4 | methyltransferase 4, N6-adenosine | ENCODES a protein that exhibits mRNA N6-methyladenosine dioxygenase activity (ortholog); RNA methyltransferase activity (ortholog); site-specific DNA-methyltransferase (adenine-specific) activity (ortholog); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); regulation of mit ochondrial DNA replication (ortholog); regulation of mitochondrial transcription (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); nucleus (ortholog); INTERACTS WITH amphetamine; bisphenol A; gentamycin | 9 | 118887740 | 118967433 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305650 | Mgat4a | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A | ENCODES a protein that exhibits acetylglucosaminyltransferase activity (ortholog); alanine-glyoxylate transaminase activity (ortholog); alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity (ortholog); INVOLVED IN glycoprotein biosynthetic process (ortholog); glyoxylate meta bolic process (ortholog); N-glycan processing (ortholog); PARTICIPATES IN N-linked glycan biosynthetic pathway; ASSOCIATED WITH COVID-19 (ortholog); pancreatic cancer (ortholog); FOUND IN peroxisome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 9 | 47169229 | 47282577 | Rat | 107 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 70927 | Mgst1 | microsomal glutathione S-transferase 1 | ENCODES a protein that exhibits glutathione binding; glutathione transferase activity; identical protein binding; INVOLVED IN Leydig cell differentiation; response to lipopolysaccharide; response to xenobiotic stimulus; PARTICIPATES IN glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; ASSOCIATED WITH chronic obstructive pulmonary disease (ortholog); COVID-19 (ortholog); neurodegenerative disease (ortholog); FOUND IN apical part of cell; endoplasmic reticulum; endoplasmic reticulum membrane; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (S)-amphetamine | 4 | 172760930 | 172776157 | Rat | 354 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305415 | Micall1 | MICAL-like 1 | ENCODES a protein that exhibits cytoskeletal anchor activity (ortholog); identical protein binding (ortholog); phosphatidic acid binding (ortholog); INVOLVED IN cellular response to nerve growth factor stimulus; neuron projection development; protein localization to endosome; FOUND IN endosome membr ane; adherens junction (ortholog); cell junction (ortholog); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; amphetamine | 7 | 112557192 | 112587618 | Rat | 184 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565674 | Mid2 | midline 2 | ENCODES a protein that exhibits enzyme binding (ortholog); identical protein binding (ortholog); microtubule binding (ortholog); INVOLVED IN host-mediated suppression of symbiont invasion (ortholog); innate immune response (ortholog); negative regulation of viral transcription (ortholog); ASSOCIATED WITH non-syndromic X-linked intellectual disability 101 (ortholog); FOUND IN microtubule (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | X | 109143057 | 109245257 | Rat | 83 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559660 | Mindy1 | MINDY lysine 48 deubiquitinase 1 | ENCODES a protein that exhibits cysteine-type carboxypeptidase activity (ortholog); K48-linked deubiquitinase activity (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN proteolysis (inferred); FOUND IN nucleoplasm (ortholog); INTERACTS WITH amph le='font-weight:700;'>amphetamine; bisphenol A; flutamide | 2 | 185550026 | 185561987 | Rat | 88 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2325528 | Mir1 | microRNA 1 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN negative regulation of thyroid gland epithelial cell proliferation; cardiac conduction system development (ortholog); cell migration involved in coronary v asculogenesis (ortholog); PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH Myocardial Reperfusion Injury; coronary artery disease (ortholog); Parkinson's disease (ortholog); FOUND IN extracellular space (ortholog); RISC complex (ortholog); INTERACTS WITH 4'-epidoxorubicin; aflatoxin B1; amphetamine | 18 | 2160327 | 2160413 | Rat | 64 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325387 | Mir125a | microRNA 125a | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN cellular response to cortisone stimulus; cellular response to glucose stimulus; cellular response to interleukin-6; ASSOCIATED WITH Binge Drinking; epileps y; lupus nephritis; FOUND IN extracellular exosome (ortholog); synapse (ortholog); INTERACTS WITH 2,5-hexanedione; 2-methoxyethanol; amphetamine | 1 | 67350675 | 67350759 | Rat | 133 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888595 | Mir126a | microRNA 126a | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN cellular response to hydrogen peroxide; negative regulation of endothelial cell apoptotic process; positive regulation of endothelial cell differentiation; ASSOCIATED WITH Cerebral Hemorrhage; Acute Coronary Syndrome (ortholog); acute myocardial infarction (ortholog); FOUND IN extracellular space (ortholog); synapse (ortholog); INTERACTS WITH 4,4'-diaminodiphenylmethane; amphetamine; atrazine | 3 | 29813150 | 29813267 | Rat | 120 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325527 | Mir133b | microRNA 133b | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN miRNA-mediated gene silencing by inhibition of translation (ortholog); miRNA-mediated post-transcriptional gene silencing (ortholog); negative regulation o f blood vessel endothelial cell migration (ortholog); ASSOCIATED WITH Vascular Calcification; hepatocellular carcinoma (ortholog); FOUND IN axon (ortholog); INTERACTS WITH amphetamine; bleomycin A2; cadmium atom | 9 | 30594582 | 30594665 | Rat | 50 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325564 | Mir152 | microRNA 152 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN negative regulation of fibroblast proliferation; cellular response to ethanol (ortholog); cellular response to leukemia inhibitory factor (ortholog); ASSOC IATED WITH Cerebral Hemorrhage; Experimental Arthritis; Experimental Liver Cirrhosis; INTERACTS WITH amphetamine; bleomycin A2; cadmium atom | 10 | 82329383 | 82329467 | Rat | 84 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325556 | Mir191 | microRNA 191 | ENCODES an ncrna that exhibits mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); long-term synaptic potentiation (ortholog); ASSOCIATED WITH alcohol use di sorder; Chemical and Drug Induced Liver Injury (ortholog); congestive heart failure (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH amphetamine; atrazine; bis(2-ethylhexyl) phthalate | 8 | 118142627 | 118142717 | Rat | 56 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325427 | Mir192 | microRNA 192 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to glucose stimulus (ortholog); cellular response to transforming growth factor beta stimulus (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Chemical and Drug Induced Liver Injury (ortholog); cholangiocarcinoma (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH aflatoxin B1; amphetamine; aristolochic acid A | 1 | 212994209 | 212994318 | Rat | 97 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888612 | Mir203 | microRNA 203 | INVOLVED IN cellular response to amino acid stimulus (ortholog); intestinal epithelial cell development (ortholog); miRNA-mediated post-transcriptional gene silencing (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); liver cirrhosis (ortholog); INTERACTS WITH 2-acetamido fluorene; aflatoxin B1; amphetamine | 6 | 137020691 | 137020805 | Rat | 62 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325551 | Mir204 | microRNA 204 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN negative regulation of osteoblast differentiation; positive regulation of fat cell differentiation; cellular hyperosmotic salinity response (ortholog); ASS OCIATED WITH hepatitis B (ortholog); Nerve Degeneration (ortholog); pre-eclampsia (ortholog); INTERACTS WITH 2-acetamidofluorene; amphetamine; bleomycin A2 | 1 | 229743461 | 229743570 | Rat | 96 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325377 | Mir205 | microRNA 205 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cellular response to lipopolysaccharide (ortholog); epithelial cell morphogenesis (ortholog); A SSOCIATED WITH Animal Mammary Neoplasms (ortholog); Breast Neoplasms (ortholog); lung cancer (ortholog); INTERACTS WITH 2-acetamidofluorene; aflatoxin B1; amphetamine | 13 | 107564535 | 107564642 | Rat | 102 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325548 | Mir214 | microRNA 214 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of regulatory T cell differentiation; cellular response to amino acid stimulus (ortholog); ce llular response to hypoxia (ortholog); ASSOCIATED WITH hypertension; renal hypertension; Spinal Cord Injuries; FOUND IN nucleus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2-acetamidofluorene; aflatoxin B1; amphetamine | 13 | 77121645 | 77121752 | Rat | 111 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325404 | Mir328 | microRNA 328 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN long-term synaptic potentiation (ortholog); miRNA-mediated post-transcriptional gene silencing (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); osteosarcoma (ortholog); FOUND IN extracellular exosome (ortholog); RISC complex (ortholog); INTERACTS WITH amphotericin B; bleomycin A2; cadmium atom | 19 | 50094691 | 50094774 | Rat | 49 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325360 | Mir375 | microRNA 375 | INVOLVED IN negative regulation of sprouting angiogenesis (ortholog); positive regulation of endothelial cell apoptotic process (ortholog); type B pancreatic cell development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); bacterial gastritis (ortholog); cerebrotendinous xanthomatosis (o rtholog); INTERACTS WITH 2,5-hexanedione; aflatoxin B1; amphetamine | 9 | 83906582 | 83906656 | Rat | 71 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325359 | Mir423 | microRNA 423 | ENCODES an ncrna that exhibits mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN gene expression (ortholog); glucose metabolic process (ortholog); lipid metabolic process (ortholog); ASSOCIATED WITH Kidney Reperfusion Injury; acute kidney failure (ortholog); alcoholic liver cirrhosis (ortholog); FOUND IN extracellular exosome (ortholog); INTERACTS WITH 2,5-hexanedione; 2-methoxyethanol; amphotericin B | 10 | 62412272 | 62412350 | Rat | 70 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325537 | Mir429 | microRNA 429 | ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing post-transcriptional repressor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); miRNA-mediated post-transcriptional gene silencing (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH breast cancer; Breast Neoplasms (ortholog); colorectal cancer (ortholog); INTERACTS WITH 2-acetamidofluorene; amphetamine; amphotericin B | 5 | 171929682 | 171929766 | Rat | 55 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 2325439 | Mir652 | microRNA 652 | INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cellular response to mechanical stimulus (ortholog); long-term synaptic potentiation (ortholog); ASSOCIATED WITH Experimental Liver Neoplasms (ortholog); pre-malignant neoplasm (ortholog); FOUND IN RISC complex (ortholog); INTER ACTS WITH 2,5-hexanedione; amphotericin B; bleomycin A2 | X | 111140079 | 111140159 | Rat | 22 | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 1596242 | Mmab | metabolism of cobalamin associated B | ENCODES a protein that exhibits cobalamin binding (ortholog); corrinoid adenosyltransferase activity (ortholog); transferase activity, transferring alkyl or aryl (other than methyl) groups (ortholog); INVOLVED IN cobalamin metabolic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); gly cogen storage disease I (ortholog); glycogen storage disease Ia (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 12 | 47819757 | 47833127 | Rat | 131 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308298 | Mmp25 | matrix metallopeptidase 25 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN hard palate development (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amph etamine; bisphenol A | 10 | 13164974 | 13180503 | Rat | 80 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1583091 | Morn3 | MORN repeat containing 3 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of signal transduction by p53 class mediator (ortholog); FOUND IN acrosomal vesicle (inferred); cytoplasmic vesicle (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amph tyle='font-weight:700;'>amphetamine; trichloroethene | 12 | 39166463 | 39190737 | Rat | 43 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309184 | Mppe1 | metallophosphoesterase 1 | ENCODES a protein that exhibits GPI-mannose ethanolamine phosphate phosphodiesterase activity (ortholog); manganese ion binding (ortholog); INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); GPI anchor biosynthetic process (ortholog); FOUND IN endoplasmic reticulum exi t site (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 18 | 63033329 | 63051461 | Rat | 88 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2322809 | Mrpl33 | mitochondrial ribosomal protein L33 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A | 6 | 30545794 | 30553987 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2322928 | Mrps6 | mitochondrial ribosomal protein S6 | ENCODES a protein that exhibits rRNA binding (inferred); structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); ASSOCIATED WITH coronary artery disease (ortholog); FOUND IN mitochondrial small ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha- ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 11 | 44778667 | 44834420 | Rat | 108 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2322311 | Msh6 | mutS homolog 6 | ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATP-dependent activity, acting on DNA (ortholog); INVOLVED IN mismatch repair; spermatogenesis; determination of adult lifespan (ortholog); PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endo metrial cancer pathway; ASSOCIATED WITH increased tumor incidence; premature death; ASSOCIATED WITH hereditary nonpolyposis colorectal cancer type 5; Microsatellite Instability; ataxia telangiectasia (ortholog); FOUND IN chromatin (ortholog); MutSalpha complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; gentamycin | 6 | 12316190 | 12333505 | Rat | 436 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1561732 | Mslnl | mesothelin-like | INVOLVED IN cell adhesion (inferred); FOUND IN membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 10 | 15260084 | 15276190 | Rat | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 1306803 | Mta3 | metastasis associated 1 family, member 3 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); negative regulation of DNA-templated transcription (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN CHD family mediated chromatin re modeling pathway; ASSOCIATED WITH Dwarfism (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,6-dinitrotoluene; amphetamine; atrazine | 6 | 16619575 | 16739732 | Rat | 117 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1592219 | Mtarc1 | mitochondrial amidoxime reducing component 1 | ENCODES a protein that exhibits molybdenum ion binding (ortholog); molybdopterin cofactor binding (ortholog); nitrate reductase activity (ortholog); INVOLVED IN cellular detoxification of nitrogen compound (ortholog); nitrate metabolic process (ortholog); nitric oxide biosynthetic process (ortholog) ; ASSOCIATED WITH amphetamine abuse (ortholog); FOUND IN mitochondrion (ortholog); nitric-oxide synthase complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17beta-estradiol | 13 | 98854235 | 98894208 | Rat | 137 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621257 | Mtarc2 | mitochondrial amidoxime reducing component 2 | ENCODES a protein that exhibits molybdenum ion binding (ortholog); molybdopterin cofactor binding (ortholog); nitrate reductase activity (ortholog); INVOLVED IN cellular detoxification of nitrogen compound (ortholog); nitrate metabolic process (ortholog); nitric oxide biosynthetic process (ortholog) ; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amphetamine abuse (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,4-dinitrotoluene | 13 | 98894347 | 98928754 | Rat | 112 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1584226 | Mthfsd | methenyltetrahydrofolate synthetase domain containing | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; paracetamol | 19 | 66072952 | 66086917 | Rat | 46 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1583002 | Mtx3 | metaxin 3 | INVOLVED IN mitochondrion organization (inferred); protein transport (inferred); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 2 | 25800530 | 25814755 | Rat | 52 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304865 | Muc20 | mucin 20, cell surface associated | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN hepatocyte growth factor receptor signaling pathway (ortholog); positive regulation of MAPK cascade (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); IgA glomerulonephritis (ortholog); lupus nephritis (ortho log); FOUND IN basal plasma membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; amphetamine; bisphenol A | 11 | 81492844 | 81506571 | Rat | 54 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564525 | Mxd1 | max dimerization protein 1 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH all ergic contact dermatitis (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 4 | 120654731 | 120678972 | Rat | 208 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305950 | Mybpc3 | myosin binding protein C3 | ENCODES a protein that exhibits identical protein binding (ortholog); myosin binding (ortholog); myosin heavy chain binding (ortholog); INVOLVED IN cardiac muscle contraction; regulation of striated muscle contraction; heart morphogenesis (ortholog); PARTICIPATES IN dilated cardiomyopathy pathway; h ypertrophic cardiomyopathy pathway; ASSOCIATED WITH Animal Disease Models (ortholog); arrhythmogenic right ventricular cardiomyopathy (ortholog); arrhythmogenic right ventricular dysplasia 1 (ortholog); FOUND IN striated muscle myosin thick filament; A band (ortholog); cardiac myofibril (ortholog); INTERACTS WITH acetamide; amphetamine; bisphenol A | 3 | 97550974 | 97569216 | Rat | 270 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62030 | Myh7 | myosin heavy chain 7 | ENCODES a protein that exhibits ATP binding; ATP hydrolysis activity; identical protein binding; INVOLVED IN cellular response to 3,3',5-triiodo-L-thyronine; cellular response to angiotensin; cellular response to hydrogen peroxide; PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiom yopathy pathway; myocarditis pathway; ASSOCIATED WITH Cardiomegaly; congestive heart failure; Endotoxemia; FOUND IN muscle myosin complex; myofibril; myosin filament; INTERACTS WITH (+)-schisandrin B; (R)-noradrenaline; (S)-amphetamine | 15 | 32416525 | 32439851 | Rat | 582 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308262 | Myl7 | myosin light chain 7 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); ASSOCIATED WITH Down syndrome (ortholog); hypertrophic cardiomyopathy (ortholog); FOUND IN A band (ortholog); dendritic spine (ortholog); INTERACTS WITH 3,7-dihydropurine-6-thione; 3H-1,2-dithiole-3-thione; amphetamine | 14 | 84994644 | 84997173 | Rat | 104 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621347 | Myo5b | myosin Vb | ENCODES a protein that exhibits ATP hydrolysis activity; ionotropic glutamate receptor binding; small GTPase binding; INVOLVED IN cellular response to glycine; dendritic spine morphogenesis; neurotransmitter receptor transport, endosome to plasma membrane; PARTICIPATES IN vasopressin signaling pathw ay; insulin responsive facilitative sugar transporter mediated glucose transport pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH amphetamine abuse (ortholog); Crohn's disease (ortholog); diarrhea (ortholog); FOUND IN dendritic spine; glutamatergic synapse; neuronal cell body; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 18 | 70313717 | 70613918 | Rat | 201 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306802 | Naf1 | nuclear assembly factor 1 ribonucleoprotein | ENCODES a protein that exhibits identical protein binding (ortholog); RNA binding (ortholog); telomerase RNA binding (ortholog); INVOLVED IN positive regulation of telomere maintenance via telomerase (ortholog); positive regulation of telomere maintenance via telomere lengthening (ortholog); ribosom e biogenesis (ortholog); ASSOCIATED WITH melanoma (ortholog); pulmonary fibrosis (ortholog); Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 7 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 16 | 27604228 | 27634963 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559914 | Naip5 | NLR family, apoptosis inhibitory protein 5 | ENCODES a protein that exhibits ATP binding (inferred); cysteine-type endopeptidase inhibitor activity involved in apoptotic process (inferred); metal ion binding (inferred); INVOLVED IN apoptotic process (inferred); negative regulation of apoptotic process (inferred); PARTICIPATES IN NOD-like recep tor signaling pathway; INTERACTS WITH acrylamide; amphetamine; arsenous acid | 2 | 33289785 | 33342807 | Rat | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 1305391 | Nap1l4 | nucleosome assembly protein 1-like 4 | ENCODES a protein that exhibits nucleosome binding (ortholog); INVOLVED IN nucleosome assembly (ortholog); ASSOCIATED WITH Hypoxia; FOUND IN dendrite; neuronal cell body; cytoplasm (ortholog); INTERACTS WITH amphetamine; bisphenol A; flutamide | 1 | 208139105 | 208175597 | Rat | 104 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306717 | Nat10 | N-acetyltransferase 10 | ENCODES a protein that exhibits DNA polymerase binding (ortholog); mRNA N-acetyltransferase activity (ortholog); N-acetyltransferase activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomerase (ortholog); positive regulation of translation (ortholog); protein acetylat ion (ortholog); FOUND IN midbody (ortholog); nucleolus (ortholog); small-subunit processome (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; amphetamine | 3 | 110566582 | 110604829 | Rat | 134 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305719 | Nat8l | N-acetyltransferase 8-like | ENCODES a protein that exhibits L-aspartate N-acetyltransferase activity; INVOLVED IN acetate metabolic process (ortholog); aspartate metabolic process (ortholog); positive regulation of dopamine uptake involved in synaptic transmission (ortholog); ASSOCIATED WITH microcephaly (ortholog); N-Acetylas partate Deficiency (ortholog); FOUND IN mitochondrion; cytoplasm (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 6-propyl-2-thiouracil; amphetamine | 14 | 80980629 | 80987264 | Rat | 114 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1585140 | Nbas | NBAS subunit of NRZ tethering complex | ENCODES a protein that exhibits SNARE binding (ortholog); INVOLVED IN negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (ortholog); nuclear-transcribed mRNA catabolic process (ortholog); retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (o rtholog); ASSOCIATED WITH Acute Liver Failure (ortholog); BCARD syndrome (ortholog); Desbuquois dysplasia (ortholog); FOUND IN Dsl1/NZR complex (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 6 | 41777253 | 42081895 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561571 | Nckap5l | NCK-associated protein 5-like | INVOLVED IN microtubule bundle formation (ortholog); microtubule depolymerization (ortholog); FOUND IN centrosome (ortholog); microtubule plus-end (ortholog); INTERACTS WITH acetamide; amphetamine; bisphenol A | 7 | 132433569 | 132470638 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306077 | Neil1 | nei-like DNA glycosylase 1 | ENCODES a protein that exhibits DNA N-glycosylase activity (ortholog); hydrolase activity, acting on glycosyl bonds (ortholog); lyase activity (ortholog); INVOLVED IN base-excision repair (ortholog); DNA repair (ortholog); PARTICIPATES IN base excision repair pathway; ASSOCIATED WITH abdominal obesi ty-metabolic syndrome (ortholog); Dyslipidemias (ortholog); familial hyperlipidemia (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; amphetamine; aniline | 8 | 66446106 | 66452844 | Rat | 118 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564342 | Nek10 | NIMA-related kinase 10 | ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN mucociliary clearance (ortholog); positive regulation of MAP kinase activity (ortholog); positive regulation of protein autophosphorylation (ortholog); ASSOCIATED WITH primary ciliary dyskinesia 44 (ortholog); FOUND IN p rotein kinase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amphetamine | 15 | 12808981 | 13013679 | Rat | 51 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307690 | Nfatc2 | nuclear factor of activated T-cells 2 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN B cell receptor signaling pathway (ortholog); calcineurin-NFAT signaling cascade (ortholog); cartilage dev elopment (ortholog); PARTICIPATES IN calcineurin signaling pathway; nuclear factor of activated T-cells signaling pathway; Wnt signaling, non-canonical pathway; ASSOCIATED WITH pulmonary hypertension; dilated cardiomyopathy 1A (ortholog); JOINT CONTRACTURES, OSTEOCHONDROMAS, AND B-CELL LYMPHOMA (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 3 | 177615189 | 177747493 | Rat | 249 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 6500424 | Nkrf | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A | X | 120992038 | 121010251 | Rat | 74 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307387 | Nlrp10 | NLR family, pyrin domain containing 10 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); GTPase activity (ortholog); INVOLVED IN activation of innate immune response (ortholog); defense response to fungus (ortholog); positive regulation of defense response to bacterium (ortholog); FOUND IN cytoplasm (ortholog); cytoplas mic side of plasma membrane (ortholog); cytosol (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A | 1 | 172357648 | 172365205 | Rat | 68 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309387 | Noc2l | NOC2-like nucleolar associated transcriptional repressor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); histone binding (ortholog); INVOLVED IN cellular response to UV (ortholog); negative regulation of B cell apoptotic process (ortholog); negative regulation of intrinsic apoptotic signal ing pathway (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 5 | 172102369 | 172114168 | Rat | 106 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308033 | Nol6 | nucleolar protein 6 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN condensed nuclear chromosome (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; aldehydo-D-glucose; amph etamine | 5 | 61055863 | 61083249 | Rat | 101 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3197 | Npy | neuropeptide Y | ENCODES a protein that exhibits neuropeptide Y receptor binding; G protein-coupled receptor binding (ortholog); neuropeptide activity (ortholog); INVOLVED IN adult feeding behavior; chemical synaptic transmission; developmental growth; PARTICIPATES IN neuropeptide Y metabolic pathway; ASSOCIATED WIT H alcohol preference; decreased body weight; increased alcohol consumption; ASSOCIATED WITH absence epilepsy; alcohol use disorder; Alzheimer's disease; FOUND IN extracellular space; neuronal dense core vesicle; perikaryon; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; (S)-nicotine | 4 | 80212111 | 80219310 | Rat | 432 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1589860 | Nrg4 | neuregulin 4 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN ERBB4-ERBB4 signaling pathway (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; FOUND IN extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amph style='font-weight:700;'>amphetamine | 8 | 64483559 | 64555671 | Rat | 90 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311052 | Nup160 | nucleoporin 160 | ENCODES a protein that exhibits structural constituent of nuclear pore (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); nephron development (ortholog); PARTICIPATES IN mRNA nuclear export pathway; RNA transport pathway; ASSOCIATED WITH nephrotic syndrome type 19 (ortholog); osteopetrosis (ortholog); FOUND IN kinetochore (ortholog); nuclear envelope (ortholog); nuclear pore (ortholog); INTERACTS WITH 2-methoxyethanol; 3-chloropropane-1,2-diol; amphetamine | 3 | 97120723 | 97183227 | Rat | 99 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306022 | Nup188 | nucleoporin 188 | ENCODES a protein that exhibits structural constituent of nuclear pore (inferred); INVOLVED IN protein import into nucleus (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH genetic disease (ortholog); microcephaly (ortholog); respiratory failure (ortholog); FOUND IN nuclear envelope (ortholog); INTERACTS WITH 2,4-dinitrotoluene; amphetamine; bisphenol A | 3 | 33957778 | 34014122 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310250 | Nup210l | nucleoporin 210-like | INVOLVED IN Sertoli cell development (ortholog); spermatid development (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH Spermatogenic Failure 97 (ortholog); FOUND IN nuclear membrane (inferred); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; amph an>etamine; bisphenol A | 2 | 177843647 | 177962975 | Rat | 41 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564353 | Nup62cl | nucleoporin 62 C-terminal like | ENCODES a protein that exhibits structural constituent of nuclear pore (inferred); INVOLVED IN protein transport (inferred); FOUND IN nuclear envelope (inferred); nuclear pore (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | X | 108457043 | 108513525 | Rat | 84 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 6486974 | Nynrin | NYN domain and retroviral integrase containing | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA-DNA hybrid ribonuclease activity (inferred); INVOLVED IN DNA integration (inferred); DNA metabolic process (inferred); ASSOCIATED WITH hepatoblastoma (ortholog); nephroblastoma (ortholog); Perlman syndrome (ortholog); INTERACTS WIT H 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 15 | 33302778 | 33325120 | Rat | 64 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308620 | Ocstamp | osteoclast stimulatory transmembrane protein | INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); multinuclear osteoclast differentiation (ortholog); FOUND IN membrane (inferred); INTERACTS WITH amphetamine; bisphenol A; thioacetamide | 3 | 174550420 | 174560907 | Rat | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 1308848 | Ogfod1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | ENCODES a protein that exhibits peptidyl-proline 3-dioxygenase activity (ortholog); peptidyl-proline dioxygenase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); peptidyl-proline hydroxylation (ortholog); protein hydroxylation (ortholog); FOUND IN cytoplasmic stress granule (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 19 | 10950950 | 10980519 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1333297 | Olr1585 | olfactory receptor 1585 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH amphetamine; trichloroethene; vinclozolin | 13 | 88579747 | 88595231 | Rat | 20 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1563435 | Ophn1 | oligophrenin 1 | ENCODES a protein that exhibits ionotropic glutamate receptor binding; actin binding (ortholog); GTPase activator activity (ortholog); INVOLVED IN maintenance of postsynaptic specialization structure; regulation of synaptic vesicle endocytosis; actin cytoskeleton organization (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Billuart-type X-linked syndromic intellectual developmental disorder (ortholog); cerebellar hypoplasia (ortholog); FOUND IN glutamatergic synapse; presynapse; actin cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | X | 67639956 | 68018217 | Rat | 172 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595361 | Or10j2 | olfactory receptor family 10 subfamily J member 2 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); signal transduction (inferred); FOUND IN membrane (inferred); plasma me mbrane (inferred); INTERACTS WITH aflatoxin B1 (ortholog); amphotericin B (ortholog); benzo[a]pyrene (ortholog) | 13 | 88255644 | 88256634 | Rat | 26 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1332644 | Or13a27b | olfactory receptor family 13 subfamily A member 27B | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 3,4-methylenedioxymethamphetamine; amphetamine; bisphenol A | 1 | 204823127 | 204824059 | Rat | 18 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1564287 | Osbpl3 | oxysterol binding protein-like 3 | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN bile acid biosynthetic process (inferred); lipid transport (inferred); sterol transport (inferred); FOUND IN cytosol (ortholog); nuclear membrane (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodio xine; amphetamine; astemizole | 4 | 80677383 | 80854169 | Rat | 151 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308402 | Osbpl5 | oxysterol binding protein-like 5 | ENCODES a protein that exhibits cholesterol binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN intermembrane phospholipid transfer (ortholog); phospholipid transport (ortholog); FOUND IN endoplasmic reticulum-plasma membrane co ntact site (ortholog); transporter complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 1 | 208291441 | 208362086 | Rat | 104 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309141 | Osbpl7 | oxysterol binding protein-like 7 | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN cellular response to cholesterol (ortholog); positive regulation of proteasomal protein catabolic process (ortholog); ASSOCIATED WITH cholangiocarcinoma (ortholog); encephalopathy due to defective mitochondrial and peroxisom al fission 1 (ortholog); FOUND IN autophagosome (ortholog); cytosol (ortholog); perinuclear endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 10 | 82532335 | 82549999 | Rat | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559897 | Oscar | osteoclast associated Ig-like receptor | ENCODES a protein that exhibits collagen receptor activity (ortholog); INVOLVED IN Fc-gamma receptor signaling pathway (ortholog); multinuclear osteoclast differentiation (ortholog); osteoclast differentiation (ortholog); ASSOCIATED WITH Alveolar Bone Loss; FOUND IN cell surface (ortholog); INTERACT S WITH 3,4-methylenedioxymethamphetamine; amphetamine; bisphenol A | 1 | 74521626 | 74529119 | Rat | 75 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3238 | Oxt | oxytocin/neurophysin I prepropeptide | ENCODES a protein that exhibits neuropeptide hormone activity; oxytocin receptor binding; INVOLVED IN drinking behavior; eating behavior; female pregnancy; PARTICIPATES IN oxytocin signaling pathway; ASSOCIATED WITH amphetamine abuse; Burns; Dehydration; FOUND I N extracellular space; neuronal dense core vesicle; secretory granule; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4-D | 3 | 138235754 | 138236594 | Rat | 217 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1597262 | Pacs2 | phosphofurin acidic cluster sorting protein 2 | INVOLVED IN autophagosome assembly (ortholog); endoplasmic reticulum calcium ion homeostasis (ortholog); mitochondrion-endoplasmic reticulum membrane tethering (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 66 (ortholog ); epilepsy (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH amphetamine; endosulfan; methoxychlor | 6 | 137918040 | 137977767 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3250 | Pak1 | p21 (RAC1) activated kinase 1 | ENCODES a protein that exhibits protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; INVOLVED IN cellular response to insulin stimulus; cerebellum development; establishment of cell polarity; PARTICIPATES IN adenosine signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH Acute Lung Injury; brain ischemia; Neointima; FOUND IN axon; dendrite; intercalated disc; INTERACTS WITH (+)-schisandrin B; (S)-amphetamine; 1-octadec-9-enoylglycero-3-phosphate | 1 | 161522399 | 161637623 | Rat | 339 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565236 | Pax5 | paired box 5 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN adult behavior (ortholog); cerebral cortex development (ortholog); embryonic cranial skeleton morphogenesis (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); genetic disease (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH alpha-Zearalanol; amphetamine; bis(2-ethylhexyl) phthalate | 5 | 63554784 | 63741380 | Rat | 117 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1590761 | Pcdhga1 | protocadherin gamma subfamily A, 1 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cell adhesion (inferred); homophilic cell-cell adhesion (inferred); FOUND IN membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; copper atom | 18 | 29738639 | 29919095 | Rat | 42 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1587259 | Pcdhga2 | protocadherin gamma subfamily A, 2 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cell adhesion (inferred); homophilic cell-cell adhesion (inferred); FOUND IN membrane (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; amphetamine | 18 | 29745189 | 29919095 | Rat | 37 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310676 | Pcdhga8 | protocadherin gamma subfamily A, 8 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cell adhesion (inferred); homophilic cell-cell adhesion (inferred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; diclofenac | 18 | 29805113 | 29919095 | Rat | 38 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307432 | Pcdhgb8 | protocadherin gamma subfamily B, 8 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cell adhesion (inferred); homophilic cell-cell adhesion (inferred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH amph t:700;'>amphetamine; bisphenol A; furan | 18 | 29839560 | 29919095 | Rat | 21 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1595865 | Pcnt | pericentrin | ENCODES a protein that exhibits molecular adaptor activity (inferred); INVOLVED IN brain morphogenesis (ortholog); camera-type eye development (ortholog); cerebellar cortex morphogenesis (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH Desbuquois dysplasia (ortho log); Developmental Disabilities (ortholog); Down syndrome (ortholog); FOUND IN centriolar satellite (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH aconitine; amphetamine; bisphenol A | 20 | 12189767 | 12278179 | Rat | 130 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595195 | Pcolce2 | procollagen C-endopeptidase enhancer 2 | ENCODES a protein that exhibits collagen binding (ortholog); heparin binding (ortholog); peptidase activator activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); FOUND IN extra cellular region (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 8 | 105073086 | 105130725 | Rat | 130 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359329 | Pdcd10 | programmed cell death 10 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia; negative regulation of inflammatory response; positive regulation of mesenchymal cell apoptotic process; ASSOCIATED WITH Subarachnoid Hemorrhage; varicocele; arteriovenous malformat ions of the brain (ortholog); FOUND IN cell periphery; cytoplasm; Golgi apparatus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 2 | 162602516 | 162644690 | Rat | 169 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 62054 | Pdyn | prodynorphin | ENCODES a protein that exhibits opioid peptide activity (inferred); INVOLVED IN locomotion involved in locomotory behavior; response to ethanol; response to immobilization stress; ASSOCIATED WITH alcohol dependence; alcohol use disorder; alcohol withdrawal syndrome; FOUND IN axon terminus; dendritic spine; dense core granule; INTERACTS WITH (R,R)-tramadol; (S)-amphetamine; 1,3-dinitrobenzene | 3 | 137354161 | 137366503 | Rat | 289 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305989 | Peli3 | pellino E3 ubiquitin protein ligase family member 3 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); negative regulation of extrinsic apoptotic signaling pathway (ortholog); negative regulation of protein ubiquitination (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 1 | 211659416 | 211672280 | Rat | 76 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68946 | Penk | proenkephalin | ENCODES a protein that exhibits opioid peptide activity; receptor ligand activity (ortholog); INVOLVED IN behavioral response to ethanol; cellular response to cAMP; cellular response to oxidative stress; ASSOCIATED WITH alcohol use disorder; Anhedonia; Catalepsy; FOUND IN axon; axon terminus; cell b ody fiber; INTERACTS WITH (S)-amphetamine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 5 | 21981381 | 21987074 | Rat | 291 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304926 | Pfas | phosphoribosylformylglycinamidine synthase | ENCODES a protein that exhibits phosphoribosylformylglycinamidine synthase activity (ortholog); INVOLVED IN glutamine metabolic process; response to xenobiotic stimulus; 'de novo' AMP biosynthetic process (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine mono phosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; hepatocellular carcinoma; colon adenocarcinoma (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 10 | 54189157 | 54210685 | Rat | 158 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621754 | Pggt1b | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity; heterocyclic compound binding; peptide binding; INVOLVED IN positive regulation of cell cycle; positive regulation of cell population proliferation; protein geranylgeranylation; ASSOCIATED WITH Lung Neoplasms (ortholog) ; FOUND IN CAAX-protein geranylgeranyltransferase complex; INTERACTS WITH (+)-schisandrin B; ammonium chloride; amphetamine | 18 | 41138536 | 41182145 | Rat | 116 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307773 | Pgp | phosphoglycolate phosphatase | ENCODES a protein that exhibits sn-glycerol 3-phosphatase activity; ADP phosphatase activity (ortholog); magnesium ion binding (ortholog); INVOLVED IN glycerol biosynthetic process; glycerophospholipid metabolic process; negative regulation of gluconeogenesis; PARTICIPATES IN glyoxylate and dicarbox ylate metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 10 | 13999782 | 14002408 | Rat | 125 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1592823 | Phactr4 | phosphatase and actin regulator 4 | ENCODES a protein that exhibits actin binding (ortholog); protein phosphatase 1 binding (ortholog); protein phosphatase activator activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); closure of optic fissure (ortholog); enteric nervous system development (ortholog); ASSOCIATE D WITH COVID-19 (ortholog); FOUND IN lamellipodium (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 5 | 149828716 | 149904955 | Rat | 115 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 69437 | Pick1 | protein interacting with PRKCA 1 | ENCODES a protein that exhibits actin filament binding; Arp2/3 complex binding; cytoskeletal protein binding; INVOLVED IN AMPA glutamate receptor clustering; cellular response to decreased oxygen levels; cellular response to glucose starvation; PARTICIPATES IN protein kinase C (PKC) signaling pathwa y; ASSOCIATED WITH amphetamine abuse (ortholog); substance-induced psychosis (ortholog); FOUND IN dendrite; dendritic spine; dendritic spine cytoplasm; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 112676890 | 112697275 | Rat | 218 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307251 | Pigb | phosphatidylinositol glycan anchor biosynthesis, class B | ENCODES a protein that exhibits dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity (ortholog); INVOLVED IN GPI anchor biosynthetic process (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 80 (ortholog); genetic disease (ortholog); hyperphosphatasia with impaired intellectual development syndrome 1 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; amphetamine | 8 | 82622484 | 82656323 | Rat | 54 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309498 | Pigo | phosphatidylinositol glycan anchor biosynthesis, class O | ENCODES a protein that exhibits mannose-ethanolamine phosphotransferase activity (ortholog); INVOLVED IN GPI anchor biosynthetic process (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH genetic disease (ortholog); Hirschsprung's disease (ortholog) ; hyperphosphatasia with impaired intellectual development syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 5 | 62040979 | 62052067 | Rat | 68 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1592067 | Pikfyve | phosphoinositide kinase, FYVE-type zinc finger containing | ENCODES a protein that exhibits 1-phosphatidylinositol-3-phosphate 5-kinase activity (ortholog); 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); 1-phosphatidylinositol-5-kinase activity (ortholog); INVOLVED IN 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process (orthol og); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH Crohn's disease (ortholog); Fleck corneal dystrophy (ortholog); genetic disease (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 9 | 74057488 | 74151610 | Rat | 170 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1589827 | Pirb | paired Ig-like receptor B | ENCODES a protein that exhibits amyloid-beta binding; protein homodimerization activity (ortholog); INVOLVED IN B cell homeostasis (ortholog); B cell mediated immunity (ortholog); cytokine-mediated signaling pathway (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; 17 beta-estradiol 3-benzoate; amphetamine | 1 | 74414556 | 74433015 | Rat | 106 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310867 | Pitpnm2 | phosphatidylinositol transfer protein, membrane-associated 2 | ENCODES a protein that exhibits calcium ion binding (ortholog); phosphatidylinositol transfer activity (ortholog); receptor tyrosine kinase binding (ortholog); INVOLVED IN intermembrane lipid transfer (inferred); phospholipid transport (inferred); FOUND IN cell body; INTERACTS WITH amph -weight:700;'>amphetamine; atrazine; bisphenol A | 12 | 38008399 | 38140046 | Rat | 82 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311015 | Piwil4 | piwi-like RNA-mediated gene silencing 4 | ENCODES a protein that exhibits molecular adaptor activity (ortholog); piRNA binding (ortholog); RNA endonuclease activity (ortholog); INVOLVED IN regulation of insulin secretion involved in cellular response to glucose stimulus; epithelial structure maintenance (ortholog); piRNA processing (ortholo g); ASSOCIATED WITH oligospermia (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 8 | 19817985 | 19861327 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1590611 | Pknox2 | PBX/knotted 1 homeobox 2 | ENCODES a protein that exhibits actin filament binding (ortholog); actin monomer binding (ortholog); DNA binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); Familial Prostate Cancer (ortholog); FOUND IN actin cyt oskeleton (ortholog); cytoplasm (ortholog); microtubule cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 44789464 | 45051933 | Rat | 118 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563940 | Plekha8 | pleckstrin homology domain containing A8 | ENCODES a protein that exhibits ceramide binding (ortholog); cerebroside transfer activity (ortholog); glycolipid binding (ortholog); INVOLVED IN ER to Golgi ceramide transport (ortholog); globoside biosynthetic process (ortholog); lipid transport (ortholog); FOUND IN nucleoplasm (ortholog); trans-G olgi network (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; amphetamine; bisphenol A | 4 | 85053765 | 85104376 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307016 | Plscr3 | phospholipid scramblase 3 | ENCODES a protein that exhibits calcium ion binding; phospholipid scramblase activity; calcium-dependent protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to lipopolysaccharide (ortholog); cholesterol homeostasis (ortholog); PARTICIPATES IN cardiolipin metabolic pathway; ASSOCIATED WITH intellectual disability (ortholog); obesity (ortholog); FOUND IN mitochondrial inner membrane; cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 10 | 55064349 | 55070120 | Rat | 106 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621816 | Pola1 | DNA polymerase alpha 1, catalytic subunit | ENCODES a protein that exhibits DNA-directed DNA polymerase activity; double-stranded DNA binding; purine nucleotide binding; INVOLVED IN DNA biosynthetic process; DNA replication; DNA repair (ortholog); PARTICIPATES IN DNA replication pathway; purine metabolic pathway; pyrimidine metabolic pathway; ASSOCIATED WITH aplastic anemia (ortholog); genetic disease (ortholog); Van Esch-O'Driscoll syndrome (ortholog); FOUND IN alpha DNA polymerase:primase complex; chromatin (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; aphidicolin | X | 62028475 | 62342455 | Rat | 262 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305212 | Poli | DNA polymerase iota | ENCODES a protein that exhibits DNA-directed DNA polymerase activity (ortholog); INVOLVED IN cellular response to UV-C (ortholog); translesion synthesis (ortholog); FOUND IN nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amph pan>etamine | 18 | 66389214 | 66409734 | Rat | 93 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564358 | Polr1d | RNA polymerase I and III subunit D | INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase III (ortholog); transcription elongation by RNA polymerase I (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase III transcription pathway; ASSOCIATED WITH Animal Di sease Models (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN RNA polymerase I complex (ortholog); RNA polymerase III complex (ortholog); INTERACTS WITH amphetamine; atrazine; bisphenol A | 12 | 13084505 | 13118069 | Rat | 94 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310810 | Pomk | protein-O-mannose kinase | ENCODES a protein that exhibits carbohydrate kinase activity (ortholog); phosphotransferase activity, alcohol group as acceptor (ortholog); INVOLVED IN brain development (ortholog); carbohydrate phosphorylation (ortholog); learning or memory (ortholog); ASSOCIATED WITH congenital muscular dystrophy- dystroglycanopathy type A12 (ortholog); genetic disease (ortholog); hydrocephalus (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; amphetamine; bisphenol A | 16 | 72788842 | 72801122 | Rat | 80 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1586427 | Pomt2 | protein-O-mannosyltransferase 2 | ENCODES a protein that exhibits dolichyl-phosphate-mannose-protein mannosyltransferase activity (ortholog); mannosyltransferase activity (ortholog); INVOLVED IN positive regulation of protein O-linked glycosylation; basement membrane organization (ortholog); dentate gyrus development (ortholog); PAR TICIPATES IN O-linked glycan biosynthetic pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal recessive limb-girdle muscular dystrophy (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2N (ortholog); FOUND IN dolichyl-phosphate-mannose-protein mannosyltransferase complex (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 6 | 112486416 | 112525799 | Rat | 87 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359491 | Pou5f1 | POU class 5 homeobox 1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; HMG box domain binding; INVOLVED IN regulation of DNA-templated transcription; response to benzoic acid; response to cytokine; PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH amphetamine abuse (ortholog); Carcinogenesis (ortholog); congenital heart disease (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; all-trans-retinoic acid; bisphenol A | 20 | 3227836 | 3232598 | Rat | 480 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306325 | Ppan | peter pan homolog | ENCODES a protein that exhibits rRNA binding (inferred); INVOLVED IN rRNA processing (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; amph an>etamine | 8 | 27700147 | 27704127 | Rat | 109 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308930 | Ppp1r3g | protein phosphatase 1, regulatory subunit 3G | ENCODES a protein that exhibits glycogen binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN glucose homeostasis (ortholog); positive regulation of glycogen (starch) synthase activity (ortholog); positive regulation of glycogen biosynthetic process (ortholog); FOUND IN cytoplasm (ortholog); protein phosphatase type 1 complex (ortholog); INTERACTS WITH 17beta-estradiol; amphetamine; bisphenol A | 17 | 29080407 | 29083739 | Rat | 77 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 632281 | Ppp1r9b | protein phosphatase 1, regulatory subunit 9B | ENCODES a protein that exhibits actin binding; actin filament binding; D2 dopamine receptor binding; INVOLVED IN actin filament depolymerization; cellular response to epidermal growth factor stimulus; cellular response to estradiol stimulus; ASSOCIATED WITH Cognitive Dysfunction; Parkinson's disease ; Alzheimer's disease (ortholog); FOUND IN actin cytoskeleton; cytoplasmic side of dendritic spine plasma membrane; dendritic spine; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 80434888 | 80450919 | Rat | 224 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560932 | Ppp4r4 | protein phosphatase 4, regulatory subunit 4 | ENCODES a protein that exhibits protein phosphatase inhibitor activity (ortholog); protein serine/threonine phosphatase inhibitor activity (ortholog); INVOLVED IN blastocyst hatching (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); protein serine/threonine phosphatase complex (ortholog ); INTERACTS WITH 17beta-estradiol 3-benzoate; acetamide; amphetamine | 6 | 128427884 | 128518776 | Rat | 80 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310055 | Prdm15 | PR/SET domain 15 | ENCODES a protein that exhibits promoter-specific chromatin binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of MAPK cascade (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); positive re gulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH pervasive developmental disorder (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; amphetamine; azoxystrobin | 11 | 50633973 | 50691624 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1594531 | Prdm2 | PR/SET domain 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLV ED IN response to estradiol; determination of adult lifespan (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH amphetamine abuse (ortholog); Contracture (ortholog); Thyroid Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 5 | 160704396 | 160815184 | Rat | 162 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562119 | Primpol | primase and DNA directed polymerase | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-directed DNA polymerase activity (ortholog); DNA-directed RNA polymerase activity (ortholog); INVOLVED IN error-prone translesion synthesis (ortholog); mitochondrial DNA repair (ortholog); mitochondrial DNA replication (ortholog); ASS OCIATED WITH Myopia 22, Autosomal Dominant (ortholog); retinitis pigmentosa 1 (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 16 | 52413894 | 52450975 | Rat | 77 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3389 | Prkaca | protein kinase cAMP-activated catalytic subunit alpha | ENCODES a protein that exhibits cAMP-dependent protein kinase activity; protein kinase binding; protein-containing complex binding; INVOLVED IN negative regulation of meiotic cell cycle; peptidyl-serine phosphorylation; positive regulation of cell population proliferation; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH amphetamine abuse; brain ischemia; Hypoglossal Nerve Injuries; FOUND IN cAMP-dependent protein kinase complex; neuromuscular junction; perinuclear region of cytoplasm; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dimethylhydrazine | 19 | 41059843 | 41083189 | Rat | 508 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 67383 | Prkcd | protein kinase C, delta | ENCODES a protein that exhibits diacylglycerol-dependent, calcium-independent serine/threonine kinase activity; protein kinase binding; protein serine/threonine kinase binding; INVOLVED IN apoptotic process; cellular response to glucose starvation; cellular response to insulin stimulus; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; vascular endothelial growth factor signaling pathway; ceramide signaling pathway; ASSOCIATED WITH brain ischemia; Burns; Cardiomegaly; FOUND IN postsynaptic cytosol; cell-cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine | 16 | 5775681 | 5806122 | Rat | 638 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3403 | Prl | prolactin | ENCODES a protein that exhibits hormone activity (inferred); metal ion binding (inferred); prolactin receptor binding (inferred); INVOLVED IN cellular response to ethanol; cellular response to hormone stimulus; circadian rhythm; PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH Experimental Neoplasms; fetal alcohol spectrum disorder; hyperprolactinemia; FOUND IN extracellular region; extracellular space; secretory granule; INTERACTS WITH (S)-amphetamine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol | 17 | 38287355 | 38298234 | Rat | 659 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 708348 | Prl8a5 | prolactin family 8, subfamily A, member 5 | ENCODES a protein that exhibits hormone activity (inferred); INVOLVED IN female pregnancy; FOUND IN extracellular region (inferred); INTERACTS WITH ammonium chloride; amphetamine; atrazine | 17 | 37674027 | 37680240 | Rat | 22 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304701 | Prmt6 | protein arginine methyltransferase 6 | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone H2AR3 methyltransferase activity (ortholog); INVOLVED IN cellular senescence (ortholog); chromatin remodeling (ortholog); negative regulation of DNA-templated transcription (ortholog); PARTICIPATES IN h istone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH Cocaine-Related Disorders; cocaine dependence (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; amphetamine | 2 | 200615780 | 200620790 | Rat | 152 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 708445 | Prokr2 | prokineticin receptor 2 | ENCODES a protein that exhibits G protein-coupled receptor activity; INVOLVED IN circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); amphetamine abuse (ortholog); Desbuquois dysplasia (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WIT H 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 3 | 140077629 | 140092327 | Rat | 81 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309896 | Prr12 | proline rich 12 | INVOLVED IN intracellular protein localization (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amphetamine | 1 | 104646492 | 104670454 | Rat | 68 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595906 | Prrc2b | proline-rich coiled-coil 2B | INVOLVED IN in utero embryonic development (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 3 | 35831017 | 35916854 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311446 | Prss3 | serine protease 3 | ENCODES a protein that exhibits calcium ion binding (ortholog); serine-type endopeptidase activity (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN endothelial cell migration (ortholog); proteolysis (ortholog); zymogen activation (ortholog); PARTICIPATES IN influenza A pathway; ASS OCIATED WITH urinary bladder cancer (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acrylamide; amphetamine | 4 | 71169749 | 71173223 | Rat | 78 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1593186 | Prss36 | serine protease 36 | ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN proteolysis (inferred); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 1 | 191973556 | 192002231 | Rat | 60 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559968 | Psd3 | pleckstrin and Sec7 domain containing 3 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN regulation of ARF protein signal transduction (inferred); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH amphetamine abuse (ortholog); Contracture (ortholog) ; high grade glioma (ortholog); FOUND IN cleavage furrow (ortholog); glutamatergic synapse (ortholog); membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 16 | 26238595 | 26802535 | Rat | 137 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307698 | Ptpdc1 | protein tyrosine phosphatase domain containing 1 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN cilium assembly (ortholog); smoothened signaling pathway (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl -2-thiouracil; amphetamine | 17 | 16235311 | 16284160 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559560 | Pusl1 | pseudouridine synthase like 1 | ENCODES a protein that exhibits isomerase activity (inferred); pseudouridine synthase activity (inferred); RNA binding (inferred); INVOLVED IN pseudouridine synthesis (inferred); RNA modification (inferred); tRNA processing (inferred); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrac hlorodibenzodioxine; amphetamine; bis(2-ethylhexyl) phthalate | 5 | 171773284 | 171782893 | Rat | 54 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1582817 | Pwp2 | PWP2, small subunit processome component | INVOLVED IN ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (ortholog); small-subunit processome (ortholog); INTERACTS WITH amphetamine; bisphenol A; cadmium dichloride | 20 | 10498998 | 10512631 | Rat | 88 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 728380 | Qrfpr | pyroglutamylated RFamide peptide receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH bone structure disease (ortholog); FOUND IN non-motile cilium (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amph t:700;'>amphetamine; bisphenol A | 2 | 120981235 | 121025020 | Rat | 70 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310054 | Qtrt2 | queuine tRNA-ribosyltransferase accessory subunit 2 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN tRNA wobble guanine modification (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; amitrole; amphetamine | 11 | 70312352 | 70343139 | Rat | 81 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560150 | Rab44 | RAB44, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); INVOLVED IN histamine secretion by mast cell (ortholog); histamine secretion mediated by IgE immunoglobulin (ortholog); mast cell degranulation (ortholog); FOUND IN early endosome membrane (ortholog); endoplasmic reticulum membrane (orth olog); lysosomal membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; amphetamine; bisphenol A | 20 | 7166219 | 7200114 | Rat | 58 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306749 | Rabl2 | RAB, member of RAS oncogene family like 2 | ENCODES a protein that exhibits G protein activity (ortholog); GTP binding (ortholog); INVOLVED IN cilium assembly (ortholog); flagellated sperm motility (ortholog); intraciliary transport (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; azoxystrobin | 7 | 122531787 | 122540500 | Rat | 85 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561889 | Rad54l2 | RAD54 like 2 | ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); DNA/RNA helicase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); R-loop processing (ortholog); transcription elongation by RNA polymerase II (ortholog); FOUND IN chromatin (ortholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; amphetamine; bisphenol A | 8 | 116203655 | 116305723 | Rat | 85 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619790 | Rag1 | recombination activating 1 | ENCODES a protein that exhibits endonuclease activity (ortholog); histone binding (ortholog); identical protein binding (ortholog); INVOLVED IN regulation of behavioral fear response; visual learning; adaptive immune response (ortholog); PARTICIPATES IN primary immunodeficiency pathway; ASSOCIATED W ITH decreased B cell number; decreased bone marrow cell number; decreased CD4-positive, alpha-beta T cell number; ASSOCIATED WITH Albuminuria; hypertension; Hypertensive Nephropathy; FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 3 | 108372087 | 108383184 | Rat | 222 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307228 | Raly | RALY heterogeneous nuclear ribonucleoprotein | ENCODES a protein that exhibits identical protein binding (ortholog); RNA binding (ortholog); transcription coregulator activity (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH amph 700;'>amphetamine abuse (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aconitine | 3 | 163766183 | 163830726 | Rat | 89 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560047 | Ranbp2 | RAN binding protein 2 | ENCODES a protein that exhibits protein-containing complex binding; kinase activator activity (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); INVOLVED IN response to amphetamine; centrosome localization (ortholog); negative regulation of tra nscription by RNA polymerase II (ortholog); PARTICIPATES IN CRM1 export pathway; mitochondria transport pathway; RNA transport pathway; ASSOCIATED WITH ectodermal dysplasia (ortholog); ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic periphery of the nuclear pore complex; nuclear pore; nuclear pore cytoplasmic filaments; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; DDT | 20 | 26984520 | 27036573 | Rat | 178 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1561668 | Rapgef5 | Rap guanine nucleotide exchange factor 5 | ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN ganglion development (inferred); intracellular signal transduction (inferred); positive regulation of smooth muscle cell migration (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene | 6 | 144588162 | 144822908 | Rat | 112 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305195 | Rbm11 | RNA binding motif protein 11 | ENCODES a protein that exhibits poly(U) RNA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); regulation of alternative mRNA splicing, via spliceosome (ortholog); FOUND IN nuclear speck (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 11 | 27721870 | 27731125 | Rat | 47 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561222 | Rbpms2 | RNA binding protein, mRNA processing factor 2 | ENCODES a protein that exhibits identical protein binding (ortholog); mRNA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN regulation of alternative mRNA splicing, via spliceosome; negative regulation of smooth muscle cell differentiation (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 8 | 75048159 | 75079393 | Rat | 108 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1592835 | Rcc1 | regulator of chromosome condensation 1 | ENCODES a protein that exhibits chromatin binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); histone binding (ortholog); INVOLVED IN chromosome segregation (ortholog); G1/S transition of mitotic cell cycle (ortholog); mitotic spindle organization (ortholog); FOUND IN chromati n (ortholog); condensed nuclear chromosome (ortholog); cytoplasm (ortholog); INTERACTS WITH amphetamine; Brodifacoum; thioacetamide | 5 | 149810037 | 149828475 | Rat | 134 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304959 | Rdh13 | retinol dehydrogenase 13 | ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NADP+) activity (ortholog); INVOLVED IN eye photoreceptor cell development (ortholog); response to high light intensity (ortholog); retina layer formation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); E xperimental Liver Cirrhosis (ortholog); Necrosis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 1 | 78415765 | 78444116 | Rat | 75 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1588579 | Rfx2 | regulatory factor X2 | ENCODES a protein that exhibits DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II; acrosom e assembly (ortholog); cellular response to leukemia inhibitory factor (ortholog); FOUND IN cytoplasm; nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 9 | 1691762 | 1759159 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311757 | Rgp1 | RGP1 partner of RAB6A GEF complex | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN negative regulation of protein catabolic process (ortholog); positive regulation of GTPase activity (ortholog); retrograde transport, endosome to Golgi (ortholog); FOUN D IN cytosol (ortholog); membrane (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 5 | 62630253 | 62638872 | Rat | 62 | description | gene, protein-coding, INFERRED [RefSeq] |
| 3562 | Rgs10 | regulator of G-protein signaling 10 | ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); GTPase activator activity (ortholog); INVOLVED IN response to amphetamine; G protein-coupled acetylcholine receptor signaling pathway (ortholog); positive regulation of GTPase activity ( ortholog); ASSOCIATED WITH Experimental Seizures; opioid abuse; Experimental Liver Cirrhosis (ortholog); FOUND IN axon terminus; dendritic spine; neuronal cell body; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 192376772 | 192422640 | Rat | 144 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1586146 | Rgs20 | regulator of G-protein signaling 20 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN response to amphetamine; FOUND IN cytoplasm (ortholog); trans-Golgi network (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodiox ine | 5 | 19282249 | 19412122 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3567 | Rgs4 | regulator of G-protein signaling 4 | ENCODES a protein that exhibits G-protein alpha-subunit binding; GTPase activator activity; protein kinase binding; INVOLVED IN dorsal root ganglion development; negative regulation of cell growth involved in cardiac muscle cell development; negative regulation of dopamine receptor signaling pathway ; PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; calcium signaling pathway via the calcium-sensing receptor; dopamine signaling pathway via D1 family of receptors; ASSOCIATED WITH bladder disease; Drug-Induced Dyskinesia; epilepsy; FOUND IN protein-containing complex; cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 84469593 | 84475884 | Rat | 240 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3570 | Rgs7 | regulator of G-protein signaling 7 | ENCODES a protein that exhibits G-protein alpha-subunit binding; G-protein beta-subunit binding; GTPase activator activity (ortholog); INVOLVED IN positive regulation of potassium ion transmembrane transport; regulation of G protein-coupled receptor signaling pathway; response to amph eight:700;'>amphetamine; PARTICIPATES IN dopamine signaling pathway via D1 family of receptors; dopamine signaling pathway via D2 family of receptors; G protein mediated signaling pathway via Galphai family; ASSOCIATED WITH Experimental Seizures; intellectual disability (ortholog); morphine dependence (ortholog); FOUND IN nuclear envelope; protein-containing complex; cell tip (ortholog); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 89511492 | 89941082 | Rat | 131 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 727778 | Rhebl1 | RHEB like 1 | ENCODES a protein that exhibits GTP binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); TOR signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bis phenol A | 7 | 131905207 | 131910088 | Rat | 104 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 631419 | Ric8b | RIC8 guanine nucleotide exchange factor B | ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); protein folding chaperone (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); regulation of G protein-coupled receptor signaling pathway (or tholog); sensory perception of smell (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 7 | 20636337 | 20730066 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562474 | Rif1 | replication timing regulatory factor 1 | INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); DNA damage response (ortholog); negative regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH nemaline myopathy 2 (ortholog); FOUND IN chromatin (ortholog); chromosome, telomeric region (ortholog); chromosome, telomeric repeat region (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 3 | 56963840 | 57017106 | Rat | 173 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305297 | Rlf | RLF zinc finger | ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN negative regulation of heterochromatin formation (ortholog); regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; amph ='font-weight:700;'>amphetamine | 5 | 139996782 | 140052419 | Rat | 95 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559511 | Rmnd5b | required for meiotic nuclear division 5 homolog B | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-protein transferase activity (inferred); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortho log); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 10 | 36382212 | 36394801 | Rat | 59 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359432 | Rnase2 | ribonuclease A family member 2 | ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); RNA nuclease activity (ortholog); INVOLVED IN chemotaxis (ortholog); defense response to Gram-negative bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); ASSOCIATED WITH COVID-19 (ortholog); INTERACTS W ITH acrylamide; ammonium chloride; amphetamine | 15 | 26923125 | 26923934 | Rat | 80 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303020 | Rnase6 | ribonuclease A family member 6 | ENCODES a protein that exhibits RNA nuclease activity (ortholog); INVOLVED IN antibacterial humoral response (ortholog); antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH liver disease (ortholog ); toxic encephalopathy (ortholog); FOUND IN cytoplasmic vesicle (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 15 | 26827896 | 26830807 | Rat | 88 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305953 | Rnf26 | ring finger protein 26 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN endosome organization (ortholog); negative regulation of defense response to virus (ortholog); protein K11-linked ubiquitination (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2, 3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 53351388 | 53353586 | Rat | 80 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307376 | Rpa1 | replication protein A1 | ENCODES a protein that exhibits single-stranded DNA binding; chromatin binding (ortholog); chromatin-protein adaptor activity (ortholog); INVOLVED IN base-excision repair (ortholog); chromosome organization (ortholog); DNA damage response (ortholog); PARTICIPATES IN mismatch repair pathway; nucleoti de excision repair pathway; DNA replication pathway; ASSOCIATED WITH Chloracne (ortholog); Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 6 (ortholog); FOUND IN DNA replication factor A complex; condensed chromosome (ortholog); condensed nuclear chromosome (ortholog); INTERACTS WITH (+)-schisandrin B; amphetamine; benzo[a]pyrene | 10 | 60647185 | 60698279 | Rat | 222 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310807 | Rpgrip1 | RPGR interacting protein 1 | INVOLVED IN detection of light stimulus involved in visual perception (ortholog); eye photoreceptor cell development (ortholog); neural precursor cell proliferation (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); cone dystrophy (ortholog); cone-rod dystrophy (ortholog); FOUND IN ciliar y rootlet; ciliary transition zone; axoneme (ortholog); INTERACTS WITH amphetamine; bisphenol A; decabromodiphenyl ether | 15 | 27282997 | 27341021 | Rat | 105 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305573 | Rpl38 | ribosomal protein L38 | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN 90S preribosome assembly (ortholog); axial mesoderm development (ortholog); cytoplasmic translation (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH otitis media (o rtholog); FOUND IN cytosolic large ribosomal subunit; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; amphetamine | 10 | 100200414 | 100204070 | Rat | 106 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562823 | Rps19bp1 | ribosomal protein S19 binding protein 1 | ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); small-subunit processome (ortholog); INTERACTS WITH amphetamine; bisphenol A; paracetamol | 7 | 113689636 | 113693116 | Rat | 55 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306147 | Rpusd2 | RNA pseudouridine synthase domain containing 2 | ENCODES a protein that exhibits pseudouridine synthase activity (ortholog); INVOLVED IN mRNA pseudouridine synthesis (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 3 | 126471620 | 126476869 | Rat | 53 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1591867 | Rrp12 | ribosomal RNA processing 12 | PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; amphetamine | 1 | 250621707 | 250655318 | Rat | 123 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595850 | RT1-N2 | RT1 class Ib, locus N2 | PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 20 | 2645980 | 2650260 | Rat | 24 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595920 | RT1-S2 | RT1 class Ib, locus S2 | INVOLVED IN antigen processing and presentation (inferred); antigen processing and presentation of peptide antigen via MHC class I (inferred); immune response (inferred); FOUND IN lumenal side of endoplasmic reticulum membrane (inferred); membrane (inferred); MHC class I protein complex (inferred); INTERACTS WITH acetamide; amphetamine; atrazine | 20 | 2655054 | 2664895 | Rat | 20 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306472 | Rtl6 | retrotransposon Gag like 6 | ASSOCIATED WITH substance-related disorder (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 7 | 117564780 | 117569865 | Rat | 40 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311657 | Sap130 | Sin3A associated protein 130 | INVOLVED IN embryonic placenta development (ortholog); in utero embryonic development (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); hypoplastic left heart syndrome (ortholog); FOUND IN nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 18 | 23518773 | 23619840 | Rat | 67 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1305788 | Scmh1 | Scm polycomb group protein homolog 1 | INVOLVED IN anterior/posterior pattern specification (ortholog); chromatin remodeling (ortholog); spermatogenesis (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); FOUND IN chromocenter (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH acetamide; amph ht:700;'>amphetamine; bisphenol A | 5 | 139276352 | 139401118 | Rat | 73 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309307 | Sdr39u1 | short chain dehydrogenase/reductase family 39U, member 1 | FOUND IN mitochondrion (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amphetamine | 15 | 33348057 | 33350892 | Rat | 33 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628665 | Sec11c | SEC11 homolog C, signal peptidase complex subunit | ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN signal peptide processing (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); signal peptidase complex (ortholog); INTERACTS WITH 17beta-estradiol; ammonium chloride; amph >amphetamine | 18 | 61590905 | 61607247 | Rat | 116 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311720 | Sec24d | SEC24 homolog D, COPII component | ENCODES a protein that exhibits SNARE binding (ortholog); zinc ion binding (ortholog); INVOLVED IN COPII-coated vesicle cargo loading (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH BCARD syndrome (ortholog) ; Cole-Carpenter syndrome (ortholog); Cole-Carpenter Syndrome 2 (ortholog); FOUND IN COPII vesicle coat (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 2 | 214103138 | 214211155 | Rat | 156 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3790 | Semg1 | semenogelin 1 | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN antibacterial humoral response (ortholog); coagulation (ortholog); fertilization (ortholog); FOUND IN acrosomal vesicle (ortholog); extracellular space (ortholog); protein-containing complex (ortholog); INTERACTS WITH ammonium chloride; amphetamine; bisphenol A | 3 | 173329413 | 173332261 | Rat | 52 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565105 | Serf1 | small EDRK-rich factor 1 | INVOLVED IN amyloid fibril formation (ortholog); protein destabilization (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); protein-containing complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 2 | 33210001 | 33216129 | Rat | 59 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619817 | Serpina5 | serpin family A member 5 | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity; acrosin binding (ortholog); phosphatidylcholine binding (ortholog); INVOLVED IN negative regulation of proteolysis; seminal vesicle development; seminal clot liquefaction (ortholog); PARTICIPATES IN fibrinolysis pathway; c oagulation cascade pathway; complement system pathway; ASSOCIATED WITH amphetamine abuse (ortholog); Arterial Occlusive Diseases (ortholog); cholestasis (ortholog); FOUND IN acrosomal membrane (ortholog); external side of plasma membrane (ortholog); extracellular exosome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran | 6 | 128774006 | 128793187 | Rat | 128 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628853 | Serpinb10 | serpin family B member 10 | ENCODES a protein that exhibits peptidase inhibitor activity; INVOLVED IN negative regulation of proteolysis; PARTICIPATES IN Entamoebiasis pathway; ASSOCIATED WITH COVID-19 (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH acrylamide; am monium chloride; amphetamine | 13 | 24067971 | 24085814 | Rat | 60 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303201 | Sgce | sarcoglycan, epsilon | INVOLVED IN kidney development; skeletal muscle tissue development; ASSOCIATED WITH genetic disease (ortholog); myoclonic dystonia (ortholog); myoclonic dystonia 11 (ortholog); FOUND IN dendrite membrane (ortholog); dystrophin-associated glycoprotein complex (ortholog); Golgi apparatus (ortholog); I NTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 4 | 33738066 | 33808907 | Rat | 89 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307788 | Sgcz | sarcoglycan zeta | ASSOCIATED WITH amphetamine abuse (ortholog); skin disease (ortholog); FOUND IN plasma membrane (ortholog); sarcoglycan complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; methoxychlor | 16 | 60363718 | 61444256 | Rat | 40 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565739 | Sgpp2 | sphingosine-1-phosphate phosphatase 2 | ENCODES a protein that exhibits sphingosine-1-phosphate phosphatase activity (ortholog); INVOLVED IN regulation of type B pancreatic cell proliferation (ortholog); sphingosine metabolic process (ortholog); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; FOUN D IN endoplasmic reticulum (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 9 | 87211155 | 87331787 | Rat | 102 | description | gene, protein-coding, INFERRED [RefSeq] |
| 735113 | Sgsm3 | small G protein signaling modulator 3 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN endosomal transport (ortholog); plasma membrane to endosome transport (ortholog); positive regulation of GTPase activity (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Autoso mal Recessive Intellectual Developmental Disorder 84 (ortholog); FOUND IN cytosol (ortholog); gap junction (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; amphetamine | 7 | 114394724 | 114424285 | Rat | 99 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1589772 | Sh3rf3 | SH3 domain containing ring finger 3 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of JNK cascade (ortholog); protein autoubiquitination (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); FOUND IN nucleoplasm (ortholog); INTERAC TS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 20 | 27306937 | 27642315 | Rat | 90 | description | gene, protein-coding, MODEL [RefSeq] |
| 3673 | Shh | sonic hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (ortholog); cholesterol-protein transferase activity (ortholog); glycosaminoglycan binding (ortholog); INVOLVED IN cellular response to L-glutamate; commissural neuron axon guidance; digestive tract mesoderm development; PARTICIPATES IN altered Hed gehog signaling pathway; forkhead class A signaling pathway; glypican signaling pathway; ASSOCIATED WITH Anorectal Malformations; chronic kidney disease; esophageal atresia/tracheoesophageal fistula; FOUND IN axon; dendrite; extracellular space; INTERACTS WITH (S)-amphetamine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol | 4 | 7687872 | 7697025 | Rat | 694 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310342 | Shprh | SNF2 histone linker PHD RING helicase | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); protein polyubiquitination (ortholog); FOUND IN nucleosome (inferred); nucleus (in ferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 1 | 7349073 | 7422804 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 727800 | Slc10a6 | solute carrier family 10 member 6 | ENCODES a protein that exhibits symporter activity (inferred); INVOLVED IN sodium-dependent organic anion transport; ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphen ol A | 14 | 6385348 | 6407532 | Rat | 100 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620101 | Slc17a7 | solute carrier family 17 member 7 | ENCODES a protein that exhibits chloride channel activity; L-glutamate transmembrane transporter activity; L-glutamate uniporter activity; INVOLVED IN chloride transport; L-glutamate transmembrane transport; neural retina development; PARTICIPATES IN glutamate signaling pathway; ASSOCIATED WITH scia tic neuropathy; transient cerebral ischemia; learning disability (ortholog); FOUND IN excitatory synapse; presynaptic active zone; synapse; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 104786172 | 104798049 | Rat | 216 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311184 | Slc22a15 | solute carrier family 22, member 15 | ENCODES a protein that exhibits amino-acid betaine transmembrane transporter activity (ortholog); INVOLVED IN amino-acid betaine transport (inferred); transmembrane transport (inferred); ASSOCIATED WITH Colorectal Neoplasms (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 3,3',5,5'-te trabromobisphenol A; acrylamide; amphetamine | 2 | 191987409 | 192049859 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310565 | Slc24a5 | solute carrier family 24 member 5 | ENCODES a protein that exhibits calcium ion transmembrane transporter activity (ortholog); calcium, potassium:sodium antiporter activity (ortholog); INVOLVED IN calcium ion import (ortholog); monoatomic ion transmembrane transport (ortholog); negative regulation of melanin biosynthetic process (orth olog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH genetic disease (ortholog); ocular albinism 1 (ortholog); oculocutaneous albinism type VI (ortholog); FOUND IN trans-Golgi network (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 3 | 132772804 | 132792342 | Rat | 72 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561851 | Slc25a36l1 | solute carrier family 25 (pyrimidine nucleotide carrier ), member 36-like 1 | ENCODES a protein that exhibits pyrimidine nucleotide transmembrane transporter activity (inferred); INVOLVED IN nucleotide transport (inferred); transmembrane transport (inferred); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 19 | 49851197 | 49853288 | Rat | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 1310197 | Slc26a6 | solute carrier family 26 member 6 | ENCODES a protein that exhibits bicarbonate transmembrane transporter activity (ortholog); chloride transmembrane transporter activity (ortholog); chloride:bicarbonate antiporter activity (ortholog); INVOLVED IN estrous cycle; angiotensin-activated signaling pathway (ortholog); bicarbonate transport (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); Hyperoxaluria (ortholog); FOUND IN apical plasma membrane; basolateral plasma membrane (ortholog); brush border membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 8 | 118438110 | 118448271 | Rat | 224 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 69296 | Slc29a2 | solute carrier family 29 member 2 | ENCODES a protein that exhibits nucleobase transmembrane transporter activity; nucleoside transmembrane transporter activity; uridine transmembrane transporter activity; INVOLVED IN adenine transport; adenosine transport; cellular response to insulin stimulus; PARTICIPATES IN azathioprine pharmacody namics pathway; mercaptopurine pharmacodynamics pathway; mercaptopurine pharmacokinetics pathway; FOUND IN apical plasma membrane; basolateral plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-amphetamine; ammonium chloride; bisphenol A | 1 | 211756588 | 211764561 | Rat | 204 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306109 | Slc35g2 | solute carrier family 35, member G2 | ASSOCIATED WITH melanoma (ortholog); FOUND IN Golgi apparatus (ortholog); plasma membrane (ortholog); synaptic vesicle membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 109964589 | 109992347 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307953 | Slc38a12 | solute carrier family 38 member 12 | ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN membrane (inferred); INTERACTS WITH acetamide; amphetamine; bisphenol A | 10 | 100926219 | 100984870 | Rat | 48 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621822 | Slc6a2 | solute carrier family 6 member 2 | ENCODES a protein that exhibits alpha-tubulin binding; beta-tubulin binding; norepinephrine:sodium symporter activity; INVOLVED IN norepinephrine transport; response to xenobiotic stimulus; monoamine transport (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynam ics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH depressive disorder; alcohol dependence (ortholog); heart conduction disease (ortholog); FOUND IN cell surface; presynaptic membrane; synaptic vesicle membrane; INTERACTS WITH (R)-noradrenaline; (S)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether | 19 | 30183289 | 30228292 | Rat | 265 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3715 | Slc6a3 | solute carrier family 6 member 3 | ENCODES a protein that exhibits amine binding; dopamine:sodium symporter activity; heterocyclic compound binding; INVOLVED IN dopamine transport; response to cAMP; response to ethanol; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacody namics pathway; ASSOCIATED WITH heroin dependence; high grade glioma; hyperprolactinemia; FOUND IN dopaminergic synapse; neuron projection; plasma membrane; INTERACTS WITH (S)-amphetamine; (S)-naringenin; (S)-nicotine | 1 | 31537990 | 31578962 | Rat | 574 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3714 | Slc6a4 | solute carrier family 6 member 4 | ENCODES a protein that exhibits actin filament binding; cocaine binding; identical protein binding; INVOLVED IN behavioral response to cocaine; cellular response to cGMP; cellular response to retinoic acid; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; bu prenorphine pharmacodynamics pathway; ASSOCIATED WITH abnormal acquisiton of operant behavior for a cocaine reinforcer; abnormal cocaine self-administration; abnormal hemostasis; ASSOCIATED WITH anxiety disorder; borna disease; Burns; FOUND IN endomembrane system; plasma membrane; postsynaptic membrane; INTERACTS WITH (S)-amphetamine; 1,2-dimethylhydrazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine | 10 | 62322688 | 62357060 | Rat | 557 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621243 | Slc6a9 | solute carrier family 6 member 9 | ENCODES a protein that exhibits glycine transmembrane transporter activity; glycine:sodium symporter activity; INVOLVED IN glycine import across plasma membrane; glycine secretion, neurotransmission (ortholog); glycine transport (ortholog); ASSOCIATED WITH amphe tamine abuse (ortholog); genetic disease (ortholog); glycine encephalopathy (ortholog); FOUND IN dense core granule; endosome; hippocampal mossy fiber to CA3 synapse; INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol | 5 | 136660022 | 136694173 | Rat | 264 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565818 | Slc8b1 | solute carrier family 8 member B1 | ENCODES a protein that exhibits identical protein binding; protein homodimerization activity; calcium:sodium antiporter activity (ortholog); INVOLVED IN calcium export from the mitochondrion; calcium ion transmembrane transport (ortholog); glucose homeostasis (ortholog); PARTICIPATES IN calcium tran sport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Cerebral Hemorrhage; FOUND IN mitochondrial crista; mitochondrial inner membrane; mitochondrion; INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; amphetamine | 12 | 41690333 | 41713657 | Rat | 169 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560736 | Slc9a9 | solute carrier family 9 member A9 | ENCODES a protein that exhibits potassium:proton antiporter activity (ortholog); sodium:proton antiporter activity (ortholog); INVOLVED IN defense response to bacterium (ortholog); phagosome maturation (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH autism spectrum diso rder (ortholog); autistic disorder (ortholog); colorectal cancer (ortholog); FOUND IN early endosome (ortholog); early phagosome (ortholog); phagocytic vesicle membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 8 | 104112279 | 104675944 | Rat | 132 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1303048 | Slco4c1 | solute carrier organic anion transporter family, member 4C1 | ENCODES a protein that exhibits transmembrane transporter activity (ortholog); INVOLVED IN organic anion transport; PARTICIPATES IN multispecific organic anion transporter mediated transport pathway; ASSOCIATED WITH kidney failure; FOUND IN basolateral plasma membrane; INTERACTS WITH acrylamide; all opurinol; amphetamine | 9 | 104624802 | 104676462 | Rat | 124 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 631403 | Smug1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | ENCODES a protein that exhibits oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity; single-strand selective uracil DNA N-glycosylase activity; uracil DNA N-glycosylase activity; INVOLVED IN base-excision repair; DNA repair; PARTICIPATES IN base excision repair pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 7 | 136166157 | 136177673 | Rat | 96 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562635 | Smyd3 | SET and MYND domain containing 3 | ENCODES a protein that exhibits histone H3K36 dimethyltransferase activity (ortholog); histone H4 methyltransferase activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to dexamethasone stimulus (ortholog); establishment of protein localization (ortholog); myotube cell development (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH amphetamine abuse (ortholog); nonprogressive cerebellar ataxia with mental retardation (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 13 | 93241274 | 93798221 | Rat | 146 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3729 | Snca | synuclein alpha | ENCODES a protein that exhibits beta-tubulin binding; enzyme binding; microtubule binding; INVOLVED IN behavioral response to cocaine; cellular response to fibroblast growth factor stimulus; negative regulation of dopamine metabolic process; PARTICIPATES IN apoptotic cell death pathway; Parkinson's disease pathway; altered ubiquitin/proteasome degradation pathway; ASSOCIATED WITH decreased susceptibility to neuronal excitotoxicity; ASSOCIATED WITH amphetamine abuse; Brain Injuries; depressive disorder; FOUND IN axon terminus; cytoplasmic vesicle membrane; growth cone; INTERACTS WITH (S)-naringenin; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol | 4 | 91026474 | 91127444 | Rat | 820 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311276 | Sntg2 | syntrophin, gamma 2 | ENCODES a protein that exhibits neuroligin family protein binding (ortholog); PDZ domain binding (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); High Myopia (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamid e; amphetamine | 6 | 52529481 | 52730972 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310367 | Snx18 | sorting nexin 18 | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cleavage furrow formation (ortholog); endocytosis (ortholog); endosomal transport (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholo g); FOUND IN clathrin-coated vesicle (ortholog); cytoplasmic side of plasma membrane (ortholog); cytoplasmic vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 2 | 46965498 | 46991516 | Rat | 117 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1596162 | Snx29 | sorting nexin 29 | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amphetamine | 10 | 4391866 | 4805682 | Rat | 88 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311367 | Snx30 | sorting nexin family member 30 | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN positive regulation of autophagosome assembly (ortholog); protein transport (ortholog); FOUND IN early endosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; acetamide; amph an>etamine | 5 | 79478804 | 79608118 | Rat | 68 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628865 | Soat2 | sterol O-acyltransferase 2 | ENCODES a protein that exhibits sterol O-acyltransferase activity; cholesterol binding (ortholog); cholesterol O-acyltransferase activity (ortholog); INVOLVED IN cholesterol metabolic process; response to nutrient; cholesterol efflux (ortholog); PARTICIPATES IN kidney failure pathway; steroid biosyn thetic pathway; ASSOCIATED WITH end stage renal disease; Experimental Diabetes Mellitus; nephrotic syndrome; FOUND IN brush border (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; ammonium chloride; amphetamine | 7 | 135160424 | 135173521 | Rat | 149 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309674 | Sox13 | SRY-box transcription factor 13 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN gamma-delta T cell differentiation (ortholog); negative regulation of canonical Wnt signal ing pathway (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH albuminuria; salt-sensitive hypertension; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 13 | 47383145 | 47427572 | Rat | 131 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307364 | Spata13 | spermatogenesis associated 13 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); identical protein binding (ortholog); INVOLVED IN cell migration (ortholog); filopodium assembly (ortholog); lamellipodium assembly (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); filopodium (orthol og); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 15 | 38954585 | 39083752 | Rat | 132 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565378 | Spata22 | spermatogenesis associated 22 | INVOLVED IN spermatocyte division; fertilization (ortholog); gamete generation (ortholog); ASSOCIATED WITH abnormal meiosis; arrest of spermiogenesis; decreased testis weight; ASSOCIATED WITH Canavan disease (ortholog); Primary Ovarian Insufficiency 25 (ortholog); Spermatogenic Failure 96 (ortholog) ; FOUND IN chromosome (ortholog); INTERACTS WITH amphetamine; aristolochic acid A; bisphenol A | 10 | 58443736 | 58461578 | Rat | 43 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302956 | Spink2 | serine peptidase inhibitor, Kazal type 2 | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN acrosome assembly (ortholog); fertilization (ortholog); male germ cell proliferation (ortholog); ASSOCIATED WITH spermatogenic failure 29 (ortholog); FOUND IN acrosomal vesicle (ortholog); cytoplasm (ortholog); neuron projection (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 14 | 31321976 | 31328622 | Rat | 84 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561884 | Spns3 | SPNS lysolipid transporter 3, sphingosine-1-phosphate | ENCODES a protein that exhibits transmembrane transporter activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred); INTERACTS WITH amphetamine; bisphenol A; copper atom | 10 | 57612796 | 57667601 | Rat | 45 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306454 | Spo11 | SPO11 initiator of meiotic double strand breaks | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); DNA binding (inferred); INVOLVED IN double-strand break repair involved in meiotic recombination (ortholog); homologous chromosome pairing at meiosis (ortholog); male meiosis I (ortholog); ASSOCIATED WITH spermato genic failure 3 (ortholog); FOUND IN chromosome, telomeric region (ortholog); INTERACTS WITH 17beta-estradiol; amphetamine; bisphenol A | 3 | 182173615 | 182189273 | Rat | 66 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311713 | Spred3 | sprouty-related, EVH1 domain containing 3 | INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of lens fiber cell differentiation (ortholog); PARTICIPATES IN Jak-Stat signaling pathway; FOUND IN plasma membrane (ortholog); INTERACTS W ITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 1 | 93586259 | 93597692 | Rat | 52 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564504 | Sqor | sulfide quinone oxidoreductase | ENCODES a protein that exhibits glutathione-dependent sulfide quinone oxidoreductase activity (ortholog); sulfide:quinone oxidoreductase activity (ortholog); INVOLVED IN sulfide oxidation, using sulfide:quinone oxidoreductase (ortholog); ASSOCIATED WITH COVID-19 (ortholog); SULFIDE:QUINONE OXIDOREDU CTASE DEFICIENCY (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 3 | 130294783 | 130341655 | Rat | 144 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565642 | Srcap | Snf2-related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chrom atin remodeling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 191554043 | 191607096 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559787 | Srf | serum response factor | ENCODES a protein that exhibits histone deacetylase binding; sequence-specific DNA binding; chromatin binding (ortholog); INVOLVED IN cellular response to glucose stimulus; long-term memory; negative regulation of cell migration; PARTICIPATES IN platelet-derived growth factor signaling pathway; mito gen activated protein kinase signaling pathway; ASSOCIATED WITH hepatocellular carcinoma; hypertension; Cardiomegaly (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 9 | 21924050 | 21933338 | Rat | 298 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561162 | Srsf12 | serine and arginine rich splicing factor 12 | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN mRNA 5'-splice site recognition (ortholog); regulation of alternative mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 5 | 52402033 | 52427839 | Rat | 55 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1303161 | St8sia6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | ENCODES a protein that exhibits sialyltransferase activity (ortholog); INVOLVED IN blastocyst hatching (ortholog); carbohydrate biosynthetic process (ortholog); ganglioside biosynthetic process (ortholog); ASSOCIATED WITH COVID-19 (ortholog); prostate cancer (ortholog); FOUND IN Golgi membrane (infe rred); INTERACTS WITH acetamide; aflatoxin B1; amphetamine | 17 | 81649866 | 81847970 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307613 | Stard7 | StAR-related lipid transfer domain containing 7 | ENCODES a protein that exhibits molecular carrier activity (ortholog); phosphatidylcholine transfer activity (ortholog); INVOLVED IN establishment of skin barrier (ortholog); inflammatory response (ortholog); intermembrane phospholipid transfer (ortholog); ASSOCIATED WITH familial adult myoclonic ep ilepsy 2 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial intermembrane space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; flutamide | 3 | 134935602 | 134969140 | Rat | 92 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1302997 | Stfa3l1 | stefin A3-like 1 | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (inferred); endopeptidase inhibitor activity (inferred); peptidase inhibitor activity (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH amphetamine; bisphenol A; lidocaine | 11 | 78114013 | 78121232 | Rat | 10 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305637 | Stn1 | STN1 subunit of CST complex | ENCODES a protein that exhibits single-stranded DNA binding (ortholog); single-stranded telomeric DNA binding (ortholog); telomeric DNA binding (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomerase (ortholog); positive regulation of DNA replication (ortholog); telomere m aintenance (ortholog); ASSOCIATED WITH Cerebroretinal Microangiopathy with Calcifications and Cysts (ortholog); Cerebroretinal Microangiopathy with Calcifications and Cysts 2 (ortholog); genetic disease (ortholog); FOUND IN chromosome, telomeric region (ortholog); CST complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; amphetamine; bisphenol A | 1 | 256336916 | 256371143 | Rat | 112 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1588437 | Strip2 | striatin interacting protein 2 | FOUND IN cytoplasm (ortholog); FAR/SIN/STRIPAK complex (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine | 4 | 59503478 | 59545745 | Rat | 89 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 69430 | Stx1a | syntaxin 1A | ENCODES a protein that exhibits ATP-dependent protein binding; calcium-dependent protein binding; myosin binding; INVOLVED IN modulation of excitatory postsynaptic potential; positive regulation of calcium ion-dependent exocytosis; positive regulation of catecholamine secretion; PARTICIPATES IN insu lin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN actomyosin; glutamatergic synapse; plasma membrane; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 12 | 27278517 | 27306547 | Rat | 329 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3784 | Stx1b | syntaxin 1B | ENCODES a protein that exhibits protein domain specific binding; signaling receptor binding; protein kinase binding (ortholog); INVOLVED IN protein localization to membrane; regulation of exocytosis; vesicle-mediated transport; ASSOCIATED WITH Duchenne muscular dystrophy (ortholog); epilepsy (orthol og); Febrile Seizures (ortholog); FOUND IN presynaptic membrane; axon (ortholog); centrosome (ortholog); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 191846016 | 191864878 | Rat | 164 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1594806 | Styx | serine/threonine/tyrosine interacting protein | ENCODES a protein that exhibits F-box domain binding (ortholog); pseudophosphatase activity (ortholog); INVOLVED IN negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process (ortholog); regulation of ERK1 and ERK2 cascade (ortholog); spermatogenesis (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amphetamine | 15 | 21043738 | 21075515 | Rat | 80 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306372 | Supt4h1 | SPT4 homolog, DSIF elongation factor subunit | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription, elongation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulati on of DNA-templated transcription, elongation (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; FOUND IN DSIF complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 73036560 | 73042821 | Rat | 65 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565028 | Suv39h1 | SUV39H1 histone lysine methyltransferase | ENCODES a protein that exhibits histone H3K14ub reader activity (ortholog); histone H3K9 methyltransferase activity (ortholog); histone H3K9 trimethyltransferase activity (ortholog); INVOLVED IN response to amphetamine; response to nutrient levels; blastocyst ha tching (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; lysine degradation pathway; ASSOCIATED WITH Myocardial Reperfusion Injury; pre-malignant neoplasm; Chromosome Breakage (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); heterochromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | X | 17093059 | 17105942 | Rat | 221 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305579 | Swap70 | switching B-cell complex subunit SWAP70 | ENCODES a protein that exhibits ATP binding (ortholog); DNA binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); isotype switching (ortholog); negative regulation of actin filament depolymerization (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasm (ortholog); nucleu s (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 1 | 173702338 | 173763540 | Rat | 120 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 728906 | Synj2_v2 | synaptojanin 2, variant 2 | FOUND IN axon terminus; cytoplasmic microtubule; ruffle membrane | | | | Rat | 4 | description | gene, splice |
| 728898 | Synj2_v3 | synaptojanin 2, variant 3 | ENCODES an splice that exhibits SH3 domain binding; FOUND IN axon terminus; cytoplasmic microtubule; ruffle membrane | | | | Rat | 6 | description | gene, splice |
| 3802 | Syp | synaptophysin | ENCODES a protein that exhibits identical protein binding; protein domain specific binding; protein-containing complex binding; INVOLVED IN endocytosis; protein homooligomerization; regulation of opioid receptor signaling pathway; ASSOCIATED WITH alcohol use disorder; Alzheimer's disease; stress-rel ated disorder; FOUND IN excitatory synapse; neuron projection terminus; neuron spine; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 17beta-estradiol | X | 17521348 | 17536449 | Rat | 332 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308616 | Szt2 | SZT2 subunit of KICSTOR complex | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); central nervous system development (ortholog); ASSOCIATED WITH benign epilepsy with centrotemporal spikes (ortholog); cryptorchidism (ortholog); developmental and epileptic encephal opathy (ortholog); FOUND IN GATOR1 complex (ortholog); GATOR2 complex (ortholog); KICSTOR complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 5 | 137182648 | 137229349 | Rat | 105 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621621 | Taar1 | trace-amine-associated receptor 1 | ENCODES a protein that exhibits G protein-coupled amine receptor activity (ortholog); G protein-coupled receptor activity (ortholog); trace-amine receptor activity (ortholog); INVOLVED IN positive regulation of cAMP/PKA signal transduction; adenylate cyclase-activating G protein-coupled receptor sig naling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN endomembrane system (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 3,4-methylenedioxymethamphetamine | 1 | 23336978 | 23337976 | Rat | 136 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3807 | Tac1 | tachykinin, precursor 1 | ENCODES a protein that exhibits substance P receptor binding; neuromedin K receptor binding (ortholog); neuropeptide activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; associative learning; long-term memory; ASSOCIATED WITH Bradycardia; centra l sleep apnea; colitis; FOUND IN extracellular space; neuronal dense core vesicle; axon (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 36645344 | 36653548 | Rat | 429 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3811 | Tacr1 | tachykinin receptor 1 | ENCODES a protein that exhibits substance P receptor activity; INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; aggressive behavior; angiotensin-mediated drinking behavior; PARTICIPATES IN calcium/calcium-mediated signaling pathway; measles pathway; ASSOCIATED W ITH acute necrotizing pancreatitis; allergic rhinitis; asthma; FOUND IN cell body; cell surface; dendrite; INTERACTS WITH (S)-amphetamine; (S)-nicotine; 1,2-naphthoquinone | 4 | 116478617 | 116647492 | Rat | 248 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562997 | Taf4b | TATA-box binding protein associated factor 4b | ENCODES a protein that exhibits DNA binding (ortholog); NF-kappaB binding (ortholog); INVOLVED IN mRNA transcription by RNA polymerase II (ortholog); positive regulation of stem cell proliferation (ortholog); positive regulation of transcription initiation by RNA polymerase II (ortholog); ASSOCIATED WITH spermatogenic failure 13 (ortholog); FOUND IN fibrillar center (ortholog); nucleoplasm (ortholog); transcription factor TFIID complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 18 | 6227299 | 6360970 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1587462 | Tafa3 | TAFA chemokine like family member 3 | INVOLVED IN negative regulation of microglial cell activation (ortholog); positive regulation of microglial cell activation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amph yle='font-weight:700;'>amphetamine | 2 | 194952499 | 194968776 | Rat | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 1566290 | Tas2r143 | taste receptor, type 2, member 143 | ENCODES a protein that exhibits bitter taste receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of taste (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of tas te (inferred); FOUND IN membrane (inferred); INTERACTS WITH amphetamine; bisphenol A | 4 | 72254484 | 72255368 | Rat | 16 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564456 | Tasor2 | transcription activation suppressor family member 2 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); negative regulation of type I interferon production (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); HUSH2 complex (ortholog); I NTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 17 | 71504656 | 71559878 | Rat | 68 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307920 | Tbc1d15 | TBC1 domain family, member 15 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of cilium assembly (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular region (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amph :700;'>amphetamine | 7 | 52690770 | 52746309 | Rat | 109 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1588560 | Tbc1d16 | TBC1 domain family, member 16 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of cilium assembly (ortholog); regulation of receptor recycling (ortholog); FOUND IN cytosol (ortholog); early endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amph 700;'>amphetamine; atrazine | 10 | 104899507 | 104985233 | Rat | 98 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564987 | Tbc1d22b | TBC1 domain family, member 22B | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); INVOLVED IN regulation of cilium assembly (ortholog); INTERACTS WITH amphetamine; bisphenol A; cadmium atom | 20 | 7620716 | 7676809 | Rat | 46 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305255 | Tbc1d30 | TBC1 domain family, member 30 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN negative regulation of cilium assembly (ortholog); positive regulation of GTPase activity (ortholog); FOUND IN ciliary basal body (ortholog); cilium (ortholog); plasma membrane (ortholo g); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 7 | 58665054 | 58754427 | Rat | 85 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595491 | Tbc1d8 | TBC1 domain family, member 8 | ENCODES a protein that exhibits calcium ion binding (inferred); GTPase activator activity (inferred); INVOLVED IN regulation of cilium assembly (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 9 | 49147109 | 49257140 | Rat | 103 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1306756 | Tbcc | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activator activity (ortholog); GTPase activity (ortholog); INVOLVED IN post-chaperonin tubulin folding pathway (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); photoreceptor connecting cilium (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodi oxine; amphetamine; bisphenol A | 9 | 21596472 | 21597660 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1597456 | Tbpl1 | TATA-box binding protein like 1 | ENCODES a protein that exhibits RNA polymerase II core promoter sequence-specific DNA binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN acrosome assembly (ortholog); dTTP biosynthetic process (ortholog); spermatid nucleus differentiation ( ortholog); PARTICIPATES IN Huntington's disease pathway; FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; amphetamine; bisphenol A | 1 | 24597028 | 24622445 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3829 | Tcf12 | transcription factor 12 | ENCODES a protein that exhibits cAMP response element binding; HMG box domain binding; bHLH transcription factor binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; positive regulation of DNA-templated transcription (ortholog); positive regulation of gene expre ssion (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); craniosynostosis (ortholog); craniosynostosis 3 (ortholog); FOUND IN nucleus; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; amphetamine | 8 | 81371201 | 81682337 | Rat | 183 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305894 | Tcf7 | transcription factor 7 | ENCODES a protein that exhibits beta-catenin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN alpha-beta T cell differentiation (ortholog); canonical Wnt signaling pathway (ortholog); cellular response to interleukin-4 (ortholog); PARTICIP ATES IN Wnt signaling, canonical pathway; acute myeloid leukemia pathway; arrhythmogenic right ventricular cardiomyopathy pathway; ASSOCIATED WITH Crohn's disease (ortholog); Mycoplasma pneumoniae pneumonia (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN euchromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 10 | 36924363 | 36954279 | Rat | 200 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309850 | Tcof1 | treacle ribosome biogenesis factor 1 | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); protein-macromolecule adaptor activity (ortholog); scaffold protein binding (ortholog); INVOLVED IN neural crest cell development (ortholog); neural crest formation (ortholog); nucleolar large rRNA transcription by RNA p olymerase I (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; amphetamine | 18 | 56537437 | 56570727 | Rat | 128 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305166 | Tctn3 | tectonic family member 3 | INVOLVED IN cilium assembly (ortholog); positive regulation of apoptotic process (ortholog); smoothened signaling pathway (ortholog); ASSOCIATED WITH ciliopathy (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodib enzodioxine; amphetamine; paracetamol | 1 | 249363428 | 249374698 | Rat | 60 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305553 | Telo2 | telomere maintenance 2 | ENCODES a protein that exhibits Hsp90 protein binding (ortholog); kinase binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN protein stabilization (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); microcephaly (ort holog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear body (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 10 | 14624998 | 14640235 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560519 | Thada | THADA, armadillo repeat containing | ENCODES a protein that exhibits enzyme regulator activity (ortholog); INVOLVED IN lipid homeostasis (ortholog); negative regulation of endoplasmic reticulum calcium ion concentration (ortholog); tRNA methylation (ortholog); ASSOCIATED WITH Meniere's disease (ortholog); type 2 diabetes mellitus (orth olog); FOUND IN endoplasmic reticulum (inferred); INTERACTS WITH 3-chloropropane-1,2-diol; amphetamine; bisphenol A | 6 | 15936593 | 16240523 | Rat | 61 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593643 | Thap2 | THAP domain containing 2 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); FOUND IN nucleolus (ortholog); INTERACTS WITH amphetamine; bisphenol A; endosulfan | 7 | 52879011 | 52893680 | Rat | 60 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1306769 | Tm2d2 | TM2 domain containing 2 | FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 16 | 73719331 | 73724853 | Rat | 73 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1583947 | Tmem201 | transmembrane protein 201 | ENCODES a protein that exhibits actin filament binding (ortholog); lamin binding (ortholog); INVOLVED IN angiogenesis (ortholog); centrosome localization (ortholog); fibroblast migration (ortholog); FOUND IN cortical endoplasmic reticulum (ortholog); nuclear envelope (ortholog); nuclear inner membra ne (ortholog); INTERACTS WITH amphetamine; atrazine; endosulfan | 5 | 165449270 | 165471901 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2323264 | Tmem91 | transmembrane protein 91 | INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 1 | 90307264 | 90314796 | Rat | 42 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304758 | Tmub2 | transmembrane and ubiquitin-like domain containing 2 | INVOLVED IN ERAD pathway (inferred); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 87738662 | 87743118 | Rat | 28 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1588572 | Tnfsf14 | TNF superfamily member 14 | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ortholog); identical protein binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); positive regulation of myoblast diffe rentiation (ortholog); positive regulation of myoblast fusion (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH IgA glomerulonephritis (ortholog); multiple sclerosis (ortholog); rheumatoid arthritis (ortholog); FOUND IN extracellular space (ortholog); plasma membrane (ortholog); INTERACTS WITH amphetamine; bisphenol A; doxorubicin | 9 | 2155270 | 2160100 | Rat | 129 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307717 | Tnip2 | TNFAIP3 interacting protein 2 | ENCODES a protein that exhibits polyubiquitin modification-dependent protein binding (ortholog); protein kinase binding (ortholog); INVOLVED IN CD40 signaling pathway (ortholog); cellular response to lipopolysaccharide (ortholog); interleukin-1-mediated signaling pathway (ortholog); FOUND IN cytopla sm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; amphetamine | 14 | 80452936 | 80470141 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310027 | Tnrc6c | trinucleotide repeat containing adaptor 6C | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN embryonic hemopoiesis (ortholog); embryonic organ development (ortholog); endoderm development (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH COVID-19 (ortholog); intellectual disabili ty (ortholog); FOUND IN cytosol (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 10 | 103367498 | 103478246 | Rat | 90 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1586156 | Top2b | DNA topoisomerase II beta | ENCODES a protein that exhibits ribonucleoprotein complex binding; chromatin binding (ortholog); DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (ortholog); INVOLVED IN cellular response to ATP; cellular response to hydrogen peroxide; cellular senescence; PARTICIPATES IN doxo rubicin pharmacodynamics pathway; doxorubicin response pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); B-Cell Immunodeficiency, Distal Limb Anomalies, and Urogenital Malformations (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); heterochromatin (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-dexrazoxane; all-trans-retinoic acid; amphetamine | 15 | 11482089 | 11542464 | Rat | 204 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593240 | Traf3ip2 | Traf3 interacting protein 2 | ENCODES a protein that exhibits signaling receptor binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN B cell affinity maturation (ortholog); B cell apoptotic process (ortholog); B cell homeostasis (ortholog); ASSOCIATED WITH atopic dermatitis (ortholog); Candidiasis, Famil ial, 8 (ortholog); psoriasis (ortholog); FOUND IN cytoplasmic vesicle (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 20 | 44565992 | 44609240 | Rat | 152 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1593883 | Traf5 | TNF receptor-associated factor 5 | ENCODES a protein that exhibits identical protein binding (ortholog); thioesterase binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN CD40 signaling pathway (ortholog); interleukin-17-mediated signaling pathway (ortholog); mRNA stabilization (ortholog); PARTICIPATES IN tum or necrosis factor mediated signaling pathway; FOUND IN CD40 receptor complex (ortholog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH amphetamine; furosemide; glyphosate | 13 | 106100921 | 106149724 | Rat | 131 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304906 | Trappc2l | trafficking protein particle complex subunit 2L | INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); vesicle-mediated transport (inferred); ASSOCIATED WITH intellectual disability (ortholog); Progressive Early-Onset Encephalopathy with Episodic Rhabdomyolysis (ortholog); FOUND IN cytosol (ortholog); TRAPP complex (ort holog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 19 | 67570954 | 67574722 | Rat | 80 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306292 | Trdmt1 | tRNA aspartic acid methyltransferase 1 | ENCODES a protein that exhibits tRNA (cytidine-5-)-methyltransferase activity (ortholog); tRNA methyltransferase activity (ortholog); INVOLVED IN response to amphetamine; tRNA methylation (ortholog); tRNA modification (ortholog); PARTICIPATES IN homocysteine met abolic pathway; methionine cycle/metabolic pathway; cysteine and methionine metabolic pathway; FOUND IN cytoplasm (ortholog); INTERACTS WITH aflatoxin B1; allethrin; bisphenol A | 17 | 81510740 | 81554036 | Rat | 103 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1587021 | Treml4 | triggering receptor expressed on myeloid cells-like 4 | INVOLVED IN intracellular protein localization (ortholog); phagocytosis, engulfment (ortholog); positive regulation of defense response to virus by host (ortholog); FOUND IN endoplasmic reticulum (ortholog); endosome membrane (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17beta-estradiol ; 17beta-estradiol 3-benzoate; amphetamine | 9 | 20216569 | 20241476 | Rat | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 1307167 | Trerf1 | transcriptional regulating factor 1 | ENCODES a protein that exhibits nuclear progesterone receptor binding (ortholog); transcription coactivator activity (ortholog); transcription coactivator binding (ortholog); INVOLVED IN cellular response to progesterone stimulus (ortholog); positive regulation of DNA-templated transcription (orthol og); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; amphetamine | 9 | 21131772 | 21355830 | Rat | 125 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305238 | Trim32 | tripartite motif-containing 32 | ENCODES a protein that exhibits identical protein binding (ortholog); myosin binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN actin ubiquitination (ortholog); autophagosome assembly (ortholog); axon development (ortholog); PARTICIPATES IN ubiquitin/proteasome degrad ation pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2H (ortholog); Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 11 (ortholog); FOUND IN autophagosome (ortholog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 5 | 84020604 | 84031483 | Rat | 174 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309168 | Trim45 | tripartite motif-containing 45 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN bone development (ortholog); negative regulation of inflammatory response (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); FOUND IN cytoplasm (ortholog); cytosol (orthol og); nucleoplasm (ortholog); INTERACTS WITH amphetamine; bisphenol A; bromobenzene | 2 | 191038355 | 191047826 | Rat | 64 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1593867 | Trim68 | tripartite motif containing 68 | ENCODES a protein that exhibits histone acetyltransferase binding (ortholog); identical protein binding (ortholog); nuclear androgen receptor binding (ortholog); INVOLVED IN protein autoubiquitination (ortholog); regulation of androgen receptor signaling pathway (ortholog); FOUND IN cytoplasm (ortho log); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; gentamycin | 1 | 166525981 | 166539407 | Rat | 66 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628819 | Trpc2 | transient receptor potential cation channel subfamily C member 2 | ENCODES a protein that exhibits calmodulin binding (ortholog); diacylglycerol binding (ortholog); inositol 1,4,5 trisphosphate binding (ortholog); INVOLVED IN acrosome reaction (ortholog); aggressive behavior (ortholog); calcium ion transport (ortholog); FOUND IN dendrite membrane (ortholog); endome mbrane system (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride; amphetamine | 1 | 165871991 | 165885339 | Rat | 77 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1597140 | Trpm1 | transient receptor potential cation channel, subfamily M, member 1 | ENCODES a protein that exhibits calcium channel activity (ortholog); monoatomic cation channel activity (ortholog); monoatomic cation transmembrane transporter activity (ortholog); INVOLVED IN calcium ion import across plasma membrane (ortholog); cellular response to light stimulus (ortholog); G pro tein-coupled glutamate receptor signaling pathway (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary night blindness 1C (ortholog); Ependymomas (ortholog); FOUND IN cell tip (ortholog); dendrite (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 127130686 | 127247219 | Rat | 119 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304888 | Trpm3 | transient receptor potential cation channel, subfamily M, member 3 | ENCODES a protein that exhibits calcium channel activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); monoatomic cation channel activity (ortholog); INVOLVED IN calcium ion transmembrane transport (ortholog); monoatomic cation transport (ortholog); protein homotetramerization (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); autosomal dominant intellectual developmental disorder (ortholog); Birk-Barel syndrome (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 1 | 229099741 | 229984172 | Rat | 134 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564531 | Trpv3 | transient receptor potential cation channel, subfamily V, member 3 | ENCODES a protein that exhibits calcium channel activity (ortholog); identical protein binding (ortholog); monoatomic cation channel activity (ortholog); INVOLVED IN positive regulation of calcium ion import; negative regulation of hair cycle (ortholog); response to temperature stimulus (ortholog); ASSOCIATED WITH increased mast cell number; ASSOCIATED WITH alopecia; dermatitis; atopic dermatitis (ortholog); FOUND IN cytoplasm (ortholog); lysosome (ortholog); membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; amphetamine | 10 | 58382054 | 58413657 | Rat | 165 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305446 | Trrap | transformation/transcription domain-associated protein | ENCODES a protein that exhibits chromatin binding; transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regulation of D NA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 12 | 14851758 | 14941444 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309876 | Tspan31 | tetraspanin 31 | ASSOCIATED WITH familial melanoma (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 7 | 64774881 | 64783534 | Rat | 87 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310192 | Tspy26 | testis specific protein, Y-linked 26 | INVOLVED IN nucleosome assembly (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 3 | 162150885 | 162152961 | Rat | 35 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562416 | Tsr2 | TSR2, ribosome maturation factor | INVOLVED IN rRNA processing (inferred); ASSOCIATED WITH Diamond-Blackfan anemia 14 with mandibulofacial dysostosis (ortholog); Diamond-Blackfan anemia 15 with mandibulofacial dysostosis (ortholog); INTERACTS WITH amphetamine; bisphenol A; cobalt dichloride | X | 23507141 | 23515711 | Rat | 55 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563572 | Tstd3 | thiosulfate sulfurtransferase like domain containing 3 | ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 5 | 40091438 | 40101509 | Rat | 41 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1559518 | Ttbk1 | tau tubulin kinase 1 | ENCODES a protein that exhibits protein serine kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN learning or memory (ortholog); negative regulation of gene expression (ortholog); positive regulation of astrocyte activation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Childhood Schizophrenia (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytosol (ortholog); microtubule associated complex (ortholog); neuronal cell body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 9 | 21990973 | 22035961 | Rat | 118 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310409 | Ttc23 | tetratricopeptide repeat domain 23 | INVOLVED IN positive regulation of smoothened signaling pathway (ortholog); ASSOCIATED WITH orofaciodigital syndrome (ortholog); FOUND IN cilium (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 1 | 130656040 | 130739670 | Rat | 73 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1594541 | Ttc28 | tetratricopeptide repeat domain 28 | ENCODES a protein that exhibits kinase binding (ortholog); INVOLVED IN regulation of mitotic cell cycle (ortholog); ASSOCIATED WITH Familial Prostate Cancer (ortholog); FOUND IN midbody (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; b is(2-chloroethyl) sulfide | 12 | 51002816 | 51443461 | Rat | 111 | description | gene, protein-coding, MODEL [RefSeq] |
| 1309145 | Ttf2 | transcription termination factor 2 | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,4-dinitrotoluene; amphetamine; bis(2-ethylhexyl) phthalate | 2 | 191054942 | 191086331 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1594742 | Ttll4 | tubulin tyrosine ligase like 4 | ENCODES a protein that exhibits protein-glutamic acid ligase activity (ortholog); tubulin binding (ortholog); tubulin-glutamic acid ligase activity (ortholog); INVOLVED IN peptidyl-glutamic acid modification (ortholog); protein polyglutamylation (ortholog); regulation of blastocyst development (orth olog); ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); FOUND IN 9+0 non-motile cilium (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 9 | 83670788 | 83706891 | Rat | 64 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566117 | Ttll7 | tubulin tyrosine ligase like 7 | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); beta-tubulin binding (ortholog); tubulin-glutamic acid ligase activity (ortholog); INVOLVED IN protein polyglutamylation (ortholog); FOUND IN 9+0 non-motile cilium (ortholog); ciliary basal body (ortholog); INTERACTS WITH 6-propyl-2-t hiouracil; amphetamine; bisphenol A | 2 | 238425786 | 238549296 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311967 | Tubd1 | tubulin, delta 1 | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); structural constituent of cytoskeleton (inferred); INVOLVED IN cytoskeleton organization (ortholog); microtubule cytoskeleton organization (ortholog); positive regulation of smoothened signaling pathway (ortholog) ; ASSOCIATED WITH polydactyly (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH amitrole; amphetamine; bisphenol A | 10 | 71865446 | 71888731 | Rat | 95 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307743 | Tubgcp6 | tubulin gamma complex component 6 | ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN microtubule nucleation (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); microcephaly (ortholog); FOUND IN centrosome (ortholog); gamma-tubulin ring complex (ortholog); INTERACTS WITH 2,3,7 ,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 7 | 122057328 | 122078639 | Rat | 73 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1582742 | Ubap1l | ubiquitin associated protein 1-like | ENCODES a protein that exhibits ubiquitin binding (inferred); INVOLVED IN ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (inferred); ASSOCIATED WITH fundus dystrophy (ortholog); FOUND IN ESCRT I complex (inferred); INTERACTS WITH 2,2',5,5'-tetrachlorobiphen yl; amphetamine; bisphenol A | 8 | 74772794 | 74792753 | Rat | 44 | description | gene, protein-coding, MODEL [RefSeq] |
| 1310305 | Ubash3a | ubiquitin associated and SH3 domain containing, A | INVOLVED IN negative regulation of T cell receptor signaling pathway (ortholog); regulation of cytokine production (ortholog); ASSOCIATED WITH sclerosing cholangitis (ortholog); FOUND IN cytosol (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodi oxine; alpha-Zearalanol; amphetamine | 20 | 9292819 | 9336036 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311161 | Ufsp2 | UFM1-specific peptidase 2 | ENCODES a protein that exhibits deUFMylase activity (ortholog); INVOLVED IN negative regulation of proteolysis involved in protein catabolic process (ortholog); proteolysis (ortholog); regulation of intracellular estrogen receptor signaling pathway (ortholog); ASSOCIATED WITH Beukes hip dysplasia (o rtholog); Desbuquois dysplasia (ortholog); developmental and epileptic encephalopathy 1 (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 16 | 53004590 | 53023640 | Rat | 102 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549771 | Ugt1a9 | UDP glucuronosyltransferase family 1 member A9 | ENCODES a protein that exhibits enzyme binding (ortholog); enzyme inhibitor activity (ortholog); glucuronosyltransferase activity (ortholog); INVOLVED IN flavone metabolic process (ortholog); flavonoid metabolic process (ortholog); negative regulation of fatty acid metabolic process (ortholog); PART ICIPATES IN artemether pharmacokinetics pathway; ibuprofen pharmacodynamics pathway; ibuprofen pharmacokinetics pathway; ASSOCIATED WITH acute kidney failure (ortholog); Chemical and Drug Induced Liver Injury (ortholog); cholangiocarcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; amphotericin B | 9 | 96144786 | 96256264 | Rat | 316 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565726 | Ulk4 | unc-51 like kinase 4 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN adult behavior (ortholog); adult walking behavior (ortholog); axoneme assembly (ortholog); ASSOCIATED WITH hydrocephalus (ortholog); intellectual disability (ortholog); mult iple myeloma (ortholog); FOUND IN cilium (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; atrazine | 8 | 129548431 | 129843555 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311117 | Unc79 | unc-79 subunit of NALCN channel complex | INVOLVED IN adult behavior (ortholog); behavioral response to ethanol (ortholog); multicellular organism growth (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH ac rylamide; amphetamine; bisphenol A | 6 | 127841671 | 128092380 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309224 | Unk | unk zinc finger | ENCODES a protein that exhibits mRNA CDS binding (ortholog); ribosome binding (ortholog); INVOLVED IN cell morphogenesis involved in neuron differentiation (ortholog); in utero embryonic development (ortholog); negative regulation of cytoplasmic translation (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 101764732 | 101794847 | Rat | 70 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308188 | Upp2 | uridine phosphorylase 2 | ENCODES a protein that exhibits deoxyuridine phosphorylase activity (ortholog); identical protein binding (ortholog); pyrimidine-nucleoside phosphorylase activity (ortholog); INVOLVED IN CMP catabolic process (ortholog); dCMP catabolic process (ortholog); dTMP catabolic process (ortholog); PARTICIPA TES IN beta-ureidopropionase deficiency pathway; dihydropyrimidinase deficiency pathway; mitochondrial neurogastrointestinal encephalopathy syndrome pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN cytosol (ortholog); type III intermediate filament (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; amphetamine | 3 | 63681671 | 63726194 | Rat | 160 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304621 | Urb1 | URB1 ribosome biogenesis factor | FOUND IN fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; amphetamine; bisphenol A | 11 | 43490633 | 43551398 | Rat | 63 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1308216 | Usp44 | ubiquitin specific peptidase 44 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); deubiquitinase activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); chromosome segregation (ortholog); negative regulation of mitotic metaphase/anaphase transition (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; FOUND IN fibrillar center (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 7 | 30251142 | 30301185 | Rat | 99 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 735213 | Usp48 | ubiquitin specific peptidase 48 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN protein deubiquitination (inferred); proteolysis (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); autosomal dominant nonsyndromic deafness 85 (ortholog); prostate cancer (or tholog); FOUND IN postsynaptic membrane; cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 5 | 155083520 | 155151208 | Rat | 92 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311786 | Usp6nl | USP6 N-terminal like | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN Golgi organization (ortholog); plasma membrane to endosome transport (ortholog); positive regulation of GTPase activity (ortholog); PARTICIPATES IN platelet-derived growth factor signal ing pathway; ASSOCIATED WITH melanoma (ortholog); FOUND IN cytoplasmic vesicle (ortholog); cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 17 | 76737870 | 76865953 | Rat | 105 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359148 | Utp25 | UTP25 small subunit processome component | ENCODES a protein that exhibits U3 snoRNA binding (inferred); INVOLVED IN embryonic organ development (ortholog); positive regulation of embryonic development (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH Hirschsprung's disease (ortholog); FOUND IN nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; amphetamine; bisphenol A | 13 | 107159092 | 107180361 | Rat | 96 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311653 | Vgll4 | vestigial-like family member 4 | INVOLVED IN negative regulation of cardiac muscle cell proliferation (ortholog); negative regulation of cell growth (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodio xine; amphetamine | 4 | 149598151 | 149711186 | Rat | 121 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1585454 | Vom2r48 | vomeronasal 2 receptor, 48 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); regulation of calcium ion transport (inferred); signal transduction (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WIT H amphetamine; bisphenol A; Cuprizon | 4 | 158347664 | 158388644 | Rat | 14 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628718 | Vps54 | VPS54 subunit of GARP complex | INVOLVED IN apoptotic DNA fragmentation (ortholog); astrocyte differentiation (ortholog); cellular response to progesterone stimulus (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Nerve Degeneration (ortholog); tooth agenesis (ortholog); FOUND IN membrane; trans-Golgi n etwork; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 14 | 99580120 | 99657178 | Rat | 190 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565149 | Vps9d1 | VPS9 domain containing 1 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN vesicle-mediated transport (inferred); INTERACTS WITH amphetamine; bisphenol A; cadmium dichloride | 19 | 68185517 | 68199469 | Rat | 39 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564982 | Vsig10l | V-set and immunoglobulin domain containing 10 like | ASSOCIATED WITH COVID-19 (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 103007933 | 103016161 | Rat | 53 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562587 | Wdr38 | WD repeat domain 38 | INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); INTERACTS WITH amphetamine; bisphenol A; Cuprizon | 3 | 43158737 | 43169466 | Rat | 31 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561494 | Wdr54 | WD repeat domain 54 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN fusion of sperm to egg plasma membrane involved in single fertilization; single fertilization; negative regulation of receptor internalization (ortholog); FOUND IN cytoplasm; plasma membrane; vesicle (ortholog) ; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amphetamine | 4 | 117212677 | 117236456 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309616 | Wdr76 | WD repeat domain 76 | ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN DNA damage response (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN heterochromatin (ortholog); nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH amph >etamine; bisphenol A; gentamycin | 3 | 128910500 | 128945241 | Rat | 90 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1303042 | Wfdc15b | WAP four-disulfide core domain 15B | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH acetamide; amphetamine; bisphenol A | 3 | 173308835 | 173318772 | Rat | 12 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311480 | Xcr1 | X-C motif chemokine receptor 1 | ENCODES a protein that exhibits chemokine receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemotaxis (ortholog); release of sequestered calcium ion into cytosol (ortholog); response to cytokine (ortholog); PARTICIPATES IN chemokine mediated signaling pathway ; cytokine mediated signaling pathway; FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; amphetamine; bisphenol A | 8 | 132357020 | 132393596 | Rat | 76 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305760 | Xpc | XPC complex subunit, DNA damage recognition and repair factor | ENCODES a protein that exhibits damaged DNA binding (ortholog); DNA damage sensor activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN response to auditory stimulus; response to xenobiotic stimulus; DNA damage response (ortholog); PARTICIPATES IN altered nucleotide excisio n repair pathway; nucleotide excision repair pathway; ASSOCIATED WITH amino acid metabolic disorder (ortholog); autistic disorder (ortholog); Chromosome Aberrations (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleotide-excision repair complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 4 | 125550833 | 125578084 | Rat | 272 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306849 | Xrcc3 | X-ray repair cross complementing 3 | ENCODES a protein that exhibits crossover junction DNA endonuclease activity (ortholog); four-way junction DNA binding (ortholog); INVOLVED IN DNA repair (ortholog); double-strand break repair via homologous recombination (ortholog); interstrand cross-link repair (ortholog); PARTICIPATES IN homologo us recombination pathway of double-strand break repair; ASSOCIATED WITH basal cell carcinoma (ortholog); brain glioma (ortholog); breast cancer (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nuclear replication fork (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 6 | 136684558 | 136694822 | Rat | 189 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566176 | Yeats2 | YEATS domain containing 2 | ENCODES a protein that exhibits histone binding (ortholog); histone reader activity (ortholog); modification-dependent protein binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of cell cycle (ortholog); regulation of cell division (ortho log); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); Disease Progression (ortholog); familial adult myoclonic epilepsy (ortholog); FOUND IN ATAC complex (ortholog); mitotic spindle (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; amphetamine | 11 | 94247538 | 94333652 | Rat | 114 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564946 | Ylpm1 | YLP motif containing 1 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of telomere maintenance (ortholog); ASSOCIATED WITH myoepithelioma (ortholog); FOUND IN nu clear speck (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 6 | 110373371 | 110449578 | Rat | 92 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1560142 | Ypel4 | yippee-like 4 | ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN negative regulation of erythrocyte clearance (ortholog); negative regulation of erythrocyte differentiation (ortholog); protein localization to plasma membrane (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN nucleolu s (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acetamide; amphetamine | 3 | 90222060 | 90227395 | Rat | 50 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303095 | Zbtb1 | zinc finger and BTB domain containing 1 | ENCODES a protein that exhibits K63-linked polyubiquitin modification-dependent protein binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN B cell differentiation (ortholog); cellular response to UV (ortholog); chromatin remod eling (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 6 | 100832506 | 100864019 | Rat | 123 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621548 | Zbtb18 | zinc finger and BTB domain containing 18 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cerebellum development (ortholog); cerebral cortex development (ortholo g); hippocampus development (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder (ortholog); autosomal dominant intellectual developmental disorder 22 (ortholog); Developmental Disabilities (ortholog); FOUND IN heterochromatin (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH ammonium chloride; amphetamine; bisphenol A | 13 | 91971602 | 91980058 | Rat | 133 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 735076 | Zbtb25 | zinc finger and BTB domain containing 25 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 6 | 100807083 | 100831555 | Rat | 55 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1584121 | Zbtb32 | zinc finger and BTB domain containing 32 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN hemopoiesis (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of c ytokine production (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN nuclear chromosome (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 1 | 94969374 | 94978553 | Rat | 79 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306532 | Zbtb39 | zinc finger and BTB domain containing 39 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 7 | 65462255 | 65469806 | Rat | 58 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309236 | Zc3hav1l | ZC3HAV1 like | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amphetamine | 4 | 67957250 | 67972540 | Rat | 68 | description | gene, protein-coding, MODEL [RefSeq] |
| 1308875 | Zdhhc8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN glutamatergic synapse (ort holog); Golgi apparatus (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 11 | 96259383 | 96273588 | Rat | 64 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305757 | Zfp112 | zinc finger protein 112 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN fibrillar center (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2, 3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 88804833 | 88819889 | Rat | 43 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560188 | Zfp14 | ZFP14 zinc finger protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN blastocyst hatching (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 1 | 94396055 | 94413338 | Rat | 68 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562294 | Zfp202 | zinc finger protein 202 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (i nferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 8 | 49439849 | 49460117 | Rat | 57 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561270 | Zfp248 | zinc finger protein 248 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 4 | 153277735 | 153302545 | Rat | 51 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561950 | Zfp286a | zinc finger protein 286A | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 10 | 47949698 | 47960496 | Rat | 63 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565881 | Zfp3 | zinc finger protein 3 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); sequence-specific double-stranded DNA binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amph 700;'>amphetamine; bisphenol A | 10 | 55977027 | 55985284 | Rat | 44 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306198 | Zfp319 | zinc finger protein 319 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 17alpha-ethynylestradiol; aflatoxin B1; amphetamine | 19 | 9708881 | 9712860 | Rat | 47 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306498 | Zfp362 | zinc finger protein 362 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amph /span>etamine | 5 | 146403469 | 146437707 | Rat | 82 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 708385 | Zfp382 | zinc finger protein 382 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding; INVOLVED IN negative regulation of DNA-templated transcription; negative regulation of transcription by RNA polymerase II; ASSOCIATED WITH Neoplasm Metastasis (ort holog); FOUND IN nucleus (inferred); INTERACTS WITH 4,4'-sulfonyldiphenol; ammonium chloride; amphetamine | 1 | 94504344 | 94528316 | Rat | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563442 | Zfp385c | zinc finger protein 385C | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); zinc ion binding (inferred); FOUND IN nucleus (inferred); INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A | 10 | 86062329 | 86118454 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359606 | Zfp385d | zinc finger protein 385D | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); substance-related disorder (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8- Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl | 15 | 7473431 | 7854364 | Rat | 64 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562129 | Zfp398 | zinc finger protein 398 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 4 | 78180620 | 78214367 | Rat | 48 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307587 | Zfp41 | zinc finger protein 41 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell differentiation (inferred); DNA-templated transcription (inferred); spermatogenesis (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amph weight:700;'>amphetamine; bisphenol A | 7 | 109188010 | 109198546 | Rat | 60 | description | gene, protein-coding, MODEL [RefSeq] |
| 621664 | Zfp423 | zinc finger protein 423 | ENCODES a protein that exhibits identical protein binding; protein-containing complex binding; sequence-specific DNA binding; INVOLVED IN negative regulation of DNA-templated transcription; brown fat cell differentiation (ortholog); negative regulation of cold-induced thermogenesis (ortholog); ASSOC IATED WITH amphetamine abuse (ortholog); cerebellar disease (ortholog); chronic kidney disease (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 35282149 | 35580775 | Rat | 146 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307017 | Zfp507 | zinc finger protein 507 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleus (inferred); INTERACTS WITH (+)-schisandrin B; 2,6-dinit rotoluene; amphetamine | 1 | 97572675 | 97605449 | Rat | 58 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561526 | Zfp512 | zinc finger protein 512 | ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN constitutive heterochromatin formation (ortholog); FOUND IN pericentric heterochromatin (ortholog); INTERACTS WITH amphetamine; bisphenol A; Brodifacoum | 6 | 30696889 | 30727895 | Rat | 56 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305284 | Zfp512b | zinc finger protein 512B | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN constitutive heterochromatin formation (ortholog); nega tive regulation of miRNA transcription (ortholog); ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); FOUND IN nucleoplasm (ortholog); pericentric heterochromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 3 | 189065036 | 189075587 | Rat | 77 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1588959 | Zfp526 | zinc finger protein 526 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH DENTICI-NOVELLI NEURODEVELOPMENTAL SYNDROME (ortholog); genetic disease (ortholog); intellectual disability (ortholog ); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 1 | 89935604 | 89945669 | Rat | 49 | description | gene, protein-coding, MODEL [RefSeq] |
| 2318406 | Zfp605 | zinc finger protein 605 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nuclear lumen (inferred); nucleus (inferred); INTERACTS WITH 2,3,7,8-t etrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 12 | 52202487 | 52234782 | Rat | 54 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310412 | Zfp641 | zinc finger protein 641 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,2-dimet hylhydrazine; acrylamide; amphetamine | 7 | 131313620 | 131324149 | Rat | 73 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2323855 | Zfp683 | zinc finger protein 683 | ENCODES a protein that exhibits promoter-specific chromatin binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to ionomycin (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); negative regu lation of type II interferon production (ortholog); ASSOCIATED WITH Chloracne (ortholog); COVID-19 (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH amphetamine; tetrachloromethane; aldehydo-D-glucose (ortholog) | 5 | 151558880 | 151569937 | Rat | 43 | description | gene, protein-coding, MODEL [RefSeq] |
| 6502425 | Zfp708 | zinc finger protein 708 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH amphetamine; 1,2-dich loroethane (ortholog); 1,2-dimethylhydrazine (ortholog) | 2 | 86181796 | 86233420 | Rat | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 628698 | Zfp709 | zinc finger protein 709 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine | 16 | 17942986 | 17953720 | Rat | 46 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 150344952 | Zfp790 | zinc finger protein 420-like | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); sequence-specific double-stranded DNA binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH amph style='font-weight:700;'>amphetamine; vinclozolin; 2,3',4,4',5-Pentachlorobiphenyl (ortholog) | 1 | 94166366 | 94180766 | Rat | 44 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1583951 | Zfp81 | zinc finger protein 81 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH amph etamine; 1,2-dichloroethane (ortholog); 1,2-dimethylhydrazine (ortholog) | 7 | 13294967 | 13327636 | Rat | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 1598054 | Zfp862 | zinc finger protein 862 | ENCODES a protein that exhibits protein dimerization activity (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); ASSOCIATED WITH gingival fibromatosis (ortholog); Gingival Fibromatosis 6 (ortholog); long QT syndrome (ortholog); INTERACTS WITH aflatoxin B1; amph t-weight:700;'>amphetamine; 17beta-estradiol (ortholog) | 4 | 78783833 | 78812884 | Rat | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 6487604 | Zfp873 | zinc finger protein 873 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); INTERACTS WITH amphetamine; acrylamide (ortholog); aflatoxin B1 (ortholog) | 7 | 8577725 | 8602577 | Rat | 33 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1584032 | Zfp939 | zinc finger protein 939 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of transcription by RNA polymerase II (inferred); regulat ion of DNA-templated transcription (inferred); FOUND IN nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH amphetamine; bisphenol A; tetrachloromethane | 1 | 100254027 | 100278418 | Rat | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 2322464 | Zfp952 | zinc finger protein 952 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH amph etamine; lidocaine | 7 | 12752698 | 12765724 | Rat | 12 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308983 | Zkscan8 | zinc finger with KRAB and SCAN domains 8 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN cytosol (inferred); nucleus (inferred); INTERACTS WITH aflatoxin B1; < span style='font-weight:700;'>amphetamine; bisphenol A | 17 | 47735120 | 47753126 | Rat | 44 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593771 | Znrf3 | zinc and ring finger 3 | ENCODES a protein that exhibits frizzled binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of non-canonical Wnt signaling pathway (ortholog); negative regulation of Wnt signaling p athway (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); pancreatic cancer (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; amphetamine; bisphenol A | 14 | 84375668 | 84527465 | Rat | 114 | description | gene, protein-coding, MODEL [RefSeq] |
| 620604 | Zp1 | zona pellucida glycoprotein 1 | ENCODES a protein that exhibits structural constituent of egg coat (ortholog); INVOLVED IN single fertilization (inferred); ASSOCIATED WITH genetic disease (ortholog); Oocyte Maturation Defect 1 (ortholog); Oocyte Maturation Defect 3 (ortholog); FOUND IN egg coat (ortholog); extracellular matrix (or tholog); INTERACTS WITH ammonium chloride; amphetamine; bisphenol A | 1 | 216984343 | 216993882 | Rat | 45 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1549726 | Zpbp2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); asthma (ortholog); atrial fibrillation (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 10 | 84055184 | 84063776 | Rat | 66 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562996 | Zscan20 | zinc finger and SCAN domain containing 20 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; endosulfan | 5 | 146214023 | 146240678 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308619 | Zscan25 | zinc finger and SCAN domain containing 25 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amph etamine | 12 | 14441458 | 14451919 | Rat | 49 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 727885 | Zscan26 | zinc finger and SCAN domain containing 26 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; amphetam ine | 17 | 47843822 | 47863799 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1589719 | Hmgb1-ps2 | high mobility group box 1, pseudogene 2 | INTERACTS WITH N-methyl-4-phenylpyridinium | 17 | 30246256 | 30248135 | Rat | 1 | old_gene_name | gene, pseudo, PROVISIONAL [RefSeq] |
| 1588759 | Hmgb1-ps3 | high mobility group box 1, pseudogene 3 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 7 | 124830224 | 124832753 | Rat | 3 | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 1584050 | Hmgb1-ps8 | high-mobility group box 1, pseudogene 8 | | 16 | 39039090 | 39041318 | Rat | 1 | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 1594733 | Hmgb1l3 | high mobility group box 1 like 3 | ENCODES a protein that exhibits cytokine activity (inferred); DNA binding (inferred); heparin binding (inferred); INVOLVED IN cell development (inferred); cellular response to cytokine stimulus (inferred); chemotaxis (inferred); FOUND IN chromosome (inferred); nucleus (inferred) | 3 | 163238867 | 163253134 | Rat | 33 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |