Pknox2 (PBX/knotted 1 homeobox 2) - Rat Genome Database

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Gene: Pknox2 (PBX/knotted 1 homeobox 2) Rattus norvegicus
Analyze
Symbol: Pknox2
Name: PBX/knotted 1 homeobox 2
RGD ID: 1590611
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and actin binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including cytoskeleton; intercellular bridge; and nucleoplasm. Orthologous to human PKNOX2 (PBX/knotted 1 homeobox 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeobox protein Meis2-like; homeobox protein PKNOX2; LOC680549; similar to Pbx/knotted 1 homeobox 2; uncharacterized protein LOC680549
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,789,464 - 45,051,933 (-)NCBIGRCr8
mRatBN7.2836,600,633 - 36,863,131 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,600,636 - 36,790,940 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,610,916 - 40,800,359 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,893,988 - 39,083,446 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,756,879 - 36,946,335 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,361,698 - 39,551,700 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,361,218 - 39,551,700 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,364,740 - 39,554,742 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,136,835 - 38,325,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera837,651,569 - 37,840,535 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12412021   PMID:15339927   PMID:16847320   PMID:17049510  


Genomics

Comparative Map Data
Pknox2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,789,464 - 45,051,933 (-)NCBIGRCr8
mRatBN7.2836,600,633 - 36,863,131 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,600,636 - 36,790,940 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,610,916 - 40,800,359 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,893,988 - 39,083,446 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,756,879 - 36,946,335 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,361,698 - 39,551,700 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,361,218 - 39,551,700 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,364,740 - 39,554,742 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,136,835 - 38,325,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera837,651,569 - 37,840,535 (+)NCBICelera
Cytogenetic Map8q22NCBI
PKNOX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,164,751 - 125,433,389 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11125,164,687 - 125,433,389 (+)EnsemblGRCh38hg38GRCh38
GRCh3711125,034,647 - 125,303,285 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,539,769 - 124,808,495 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411124,726,419 - 124,808,264NCBI
Celera11122,194,601 - 122,463,611 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11120,976,463 - 121,244,840 (+)NCBIHuRef
CHM1_111124,920,619 - 125,189,521 (+)NCBICHM1_1
T2T-CHM13v2.011125,193,419 - 125,462,086 (+)NCBIT2T-CHM13v2.0
Pknox2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39936,802,278 - 37,058,637 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl936,802,278 - 37,058,703 (-)EnsemblGRCm39 Ensembl
GRCm38936,890,979 - 37,147,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl936,890,982 - 37,147,407 (-)EnsemblGRCm38mm10GRCm38
MGSCv37936,698,567 - 36,954,899 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36936,640,653 - 36,896,985 (-)NCBIMGSCv36mm8
Celera934,095,372 - 34,359,379 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.7NCBI
Pknox2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,372,846 - 26,468,926 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,214,671 - 26,468,737 (+)NCBIChiLan1.0ChiLan1.0
PKNOX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29125,807,624 - 126,128,241 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111126,912,553 - 127,240,365 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011119,991,916 - 120,259,800 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111123,906,012 - 124,173,865 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,072,715 - 124,173,865 (+)Ensemblpanpan1.1panPan2
PKNOX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.159,054,138 - 9,363,750 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl59,056,134 - 9,178,159 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha59,098,622 - 9,408,616 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,994,772 - 9,302,925 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,994,772 - 9,251,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.159,065,978 - 9,375,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.059,036,663 - 9,346,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.059,072,792 - 9,382,834 (-)NCBIUU_Cfam_GSD_1.0
Pknox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,342,759 - 107,612,737 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367431,661,791 - 1,858,278 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367431,661,783 - 1,860,299 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKNOX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,349,714 - 52,610,680 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,303,022 - 52,608,505 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,127,081 - 58,195,478 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PKNOX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,332,851 - 116,604,758 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,523,593 - 116,605,161 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,519,677 - 9,788,985 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pknox2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249271,275,956 - 1,460,170 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249271,197,610 - 1,459,777 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pknox2
984 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:99
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000048875
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82664491246711092Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
70206Alc20Alcohol consumption QTL 202drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)83084815440713225Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat

Markers in Region
D8Rat219  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2836,677,937 - 36,678,067 (+)MAPPERmRatBN7.2
Rnor_6.0839,438,423 - 39,438,552NCBIRnor6.0
Rnor_5.0839,441,465 - 39,441,594UniSTSRnor5.0
RGSC_v3.4838,212,433 - 38,212,563RGDRGSC3.4
RGSC_v3.4838,212,434 - 38,212,563UniSTSRGSC3.4
RGSC_v3.1838,221,199 - 38,221,329RGD
Celera837,764,313 - 37,764,442UniSTS
SHRSP x BN Map827.78RGD
SHRSP x BN Map827.78UniSTS
Cytogenetic Map8q21UniSTS
RH141386  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2836,600,644 - 36,600,843 (+)MAPPERmRatBN7.2
Rnor_6.0839,361,227 - 39,361,425NCBIRnor6.0
Rnor_5.0839,364,269 - 39,364,467UniSTSRnor5.0
RGSC_v3.4838,134,940 - 38,135,138UniSTSRGSC3.4
RH 3.4 Map8311.4UniSTS
Cytogenetic Map8q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 67 20 38 2
Low 3 43 42 26 19 26 8 8 7 15 3 9 8
Below cutoff 15 15 15

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000048875   ⟹   ENSRNOP00000048926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl836,600,636 - 36,700,364 (-)Ensembl
Rnor_6.0 Ensembl839,361,698 - 39,460,844 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076025   ⟹   ENSRNOP00000068263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl839,404,748 - 39,551,700 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076158   ⟹   ENSRNOP00000068159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl836,600,636 - 36,661,664 (-)Ensembl
Rnor_6.0 Ensembl839,361,458 - 39,437,270 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076232   ⟹   ENSRNOP00000068088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl836,609,889 - 36,700,364 (-)Ensembl
Rnor_6.0 Ensembl839,361,218 - 39,460,844 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl839,370,432 - 39,379,840 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091894   ⟹   ENSRNOP00000070748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl836,601,116 - 36,790,940 (-)Ensembl
Rnor_6.0 Ensembl839,361,698 - 39,551,700 (-)Ensembl
RefSeq Acc Id: NM_001271278   ⟹   NP_001258207
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,947 - 44,979,754 (-)NCBI
mRatBN7.2836,601,116 - 36,790,940 (-)NCBI
Rnor_6.0839,361,698 - 39,551,700 (-)NCBI
Rnor_5.0839,364,740 - 39,554,742 (-)NCBI
Celera837,651,569 - 37,840,535 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271279   ⟹   NP_001258208
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,947 - 44,889,186 (-)NCBI
mRatBN7.2836,601,116 - 36,700,364 (-)NCBI
Rnor_6.0839,361,698 - 39,460,844 (-)NCBI
Rnor_5.0839,364,740 - 39,554,742 (-)NCBI
Celera837,742,046 - 37,840,535 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039082131   ⟹   XP_038938059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,051,925 (-)NCBI
mRatBN7.2836,600,633 - 36,863,131 (-)NCBI
RefSeq Acc Id: XM_039082132   ⟹   XP_038938060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,050,799 (-)NCBI
mRatBN7.2836,600,633 - 36,862,010 (-)NCBI
RefSeq Acc Id: XM_039082133   ⟹   XP_038938061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,051,920 (-)NCBI
mRatBN7.2836,600,633 - 36,863,131 (-)NCBI
RefSeq Acc Id: XM_039082134   ⟹   XP_038938062
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,915,743 (-)NCBI
mRatBN7.2836,600,633 - 36,726,911 (-)NCBI
RefSeq Acc Id: XM_039082135   ⟹   XP_038938063
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,921,673 (-)NCBI
mRatBN7.2836,600,633 - 36,732,781 (-)NCBI
RefSeq Acc Id: XM_039082136   ⟹   XP_038938064
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,917,664 (-)NCBI
mRatBN7.2836,600,633 - 36,730,176 (-)NCBI
RefSeq Acc Id: XM_039082137   ⟹   XP_038938065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,917,664 (-)NCBI
mRatBN7.2836,600,633 - 36,730,176 (-)NCBI
RefSeq Acc Id: XM_039082138   ⟹   XP_038938066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,917,591 (-)NCBI
mRatBN7.2836,600,633 - 36,728,725 (-)NCBI
RefSeq Acc Id: XM_039082139   ⟹   XP_038938067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,917,652 (-)NCBI
mRatBN7.2836,600,633 - 36,730,176 (-)NCBI
RefSeq Acc Id: XM_039082140   ⟹   XP_038938068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,889,081 (-)NCBI
mRatBN7.2836,600,633 - 36,700,766 (-)NCBI
RefSeq Acc Id: XM_039082142   ⟹   XP_038938070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,051,921 (-)NCBI
mRatBN7.2836,600,633 - 36,863,131 (-)NCBI
RefSeq Acc Id: XM_039082143   ⟹   XP_038938071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,051,921 (-)NCBI
mRatBN7.2836,600,633 - 36,863,131 (-)NCBI
RefSeq Acc Id: XM_039082145   ⟹   XP_038938073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,851,985 (-)NCBI
mRatBN7.2836,600,633 - 36,663,139 (-)NCBI
RefSeq Acc Id: XM_039082146   ⟹   XP_038938074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,051,933 (-)NCBI
mRatBN7.2836,600,633 - 36,863,131 (-)NCBI
RefSeq Acc Id: XM_039082148   ⟹   XP_038938076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,822,458 (-)NCBI
mRatBN7.2836,600,633 - 36,633,631 (-)NCBI
RefSeq Acc Id: XM_063266115   ⟹   XP_063122185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,042,777 (-)NCBI
RefSeq Acc Id: XM_063266116   ⟹   XP_063122186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,915,744 (-)NCBI
RefSeq Acc Id: XM_063266117   ⟹   XP_063122187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 45,051,920 (-)NCBI
RefSeq Acc Id: XM_063266119   ⟹   XP_063122189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,979,751 (-)NCBI
RefSeq Acc Id: XM_063266120   ⟹   XP_063122190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,917,652 (-)NCBI
RefSeq Acc Id: XM_063266121   ⟹   XP_063122191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,789,464 - 44,850,478 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001258207 (Get FASTA)   NCBI Sequence Viewer  
  NP_001258208 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938059 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938060 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938061 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938062 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938063 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938064 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938065 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938066 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938067 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938068 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938070 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938071 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938073 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938074 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938076 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122185 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122186 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122187 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122189 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122190 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122191 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84053 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048926.5
  ENSRNOP00000068088.2
  ENSRNOP00000068159
  ENSRNOP00000068159.2
  ENSRNOP00000070748
  ENSRNOP00000070748.2
Reference Protein Sequences
RefSeq Acc Id: NP_001258207   ⟸   NM_001271278
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258208   ⟸   NM_001271279
- Peptide Label: isoform 2
- UniProtKB: A0A096MJK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000048926   ⟸   ENSRNOT00000048875
RefSeq Acc Id: ENSRNOP00000070748   ⟸   ENSRNOT00000091894
RefSeq Acc Id: ENSRNOP00000068088   ⟸   ENSRNOT00000076232
RefSeq Acc Id: ENSRNOP00000068263   ⟸   ENSRNOT00000076025
RefSeq Acc Id: ENSRNOP00000068159   ⟸   ENSRNOT00000076158
RefSeq Acc Id: XP_038938070   ⟸   XM_039082142
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938071   ⟸   XM_039082143
- Peptide Label: isoform X2
- UniProtKB: A0A096MJK1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938074   ⟸   XM_039082146
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038938059   ⟸   XM_039082131
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938061   ⟸   XM_039082133
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938060   ⟸   XM_039082132
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938063   ⟸   XM_039082135
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938067   ⟸   XM_039082139
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938064   ⟸   XM_039082136
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938065   ⟸   XM_039082137
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938066   ⟸   XM_039082138
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938062   ⟸   XM_039082134
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938068   ⟸   XM_039082140
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938073   ⟸   XM_039082145
- Peptide Label: isoform X2
- UniProtKB: A0A096MJK1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938076   ⟸   XM_039082148
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063122187   ⟸   XM_063266117
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122185   ⟸   XM_063266115
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122189   ⟸   XM_063266119
- Peptide Label: isoform X2
- UniProtKB: A0A096MJK1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122190   ⟸   XM_063266120
- Peptide Label: isoform X2
- UniProtKB: A0A096MJK1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122186   ⟸   XM_063266116
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ2 (UniProtKB/TrEMBL),   A6KRM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122191   ⟸   XM_063266121
- Peptide Label: isoform X4
Protein Domains
Homeobox

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1590611 AgrOrtholog
BioCyc Gene G2FUF-31098 BioCyc
Ensembl Genes ENSRNOG00000028856 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048875.6 UniProtKB/TrEMBL
  ENSRNOT00000076158.3 UniProtKB/TrEMBL
  ENSRNOT00000076232.3 UniProtKB/TrEMBL
  ENSRNOT00000091894 ENTREZGENE
  ENSRNOT00000091894.2 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox_KN_domain UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  PKNOX/Meis_N UniProtKB/TrEMBL
KEGG Report rno:680549 UniProtKB/TrEMBL
NCBI Gene 680549 ENTREZGENE
PANTHER HOMEOBOX PROTEIN PKNOX2 UniProtKB/TrEMBL
  HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  Meis_PKNOX_N UniProtKB/TrEMBL
PhenoGen Pknox2 PhenoGen
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028856 RatGTEx
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A096MJD5_RAT UniProtKB/TrEMBL
  A0A096MJK1 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JYQ2 ENTREZGENE, UniProtKB/TrEMBL
  A6KRM3 ENTREZGENE, UniProtKB/TrEMBL
  D4ACG5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-09 Pknox2  PBX/knotted 1 homeobox 2  LOC680549  similar to Pbx/knotted 1 homeobox 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 LOC680549  similar to Pbx/knotted 1 homeobox 2  LOC100364346  homeobox protein Meis2-like  Data merged from RGD:2321212 1643240 APPROVED
2010-05-05 LOC100364346  homeobox protein Meis2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC680549  similar to Pbx/knotted 1 homeobox 2  LOC682375  similar to Pbx/knotted 1 homeobox 2  Data merged from RGD:1584574 1643240 APPROVED
2006-11-20 LOC680549  similar to Pbx/knotted 1 homeobox 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682375  similar to Pbx/knotted 1 homeobox 2      Symbol and Name status set to provisional 70820 PROVISIONAL