Gene: Gla (galactosidase, alpha) Rattus norvegicus
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Symbol: Gla
Name: galactosidase, alpha
Description: ENCODES a protein that exhibits alpha-galactosidase activity; galactoside binding; catalytic activity (ortholog); INVOLVED IN glycosylceramide catabolic process (ortholog); negative regulation of nitric oxide biosynthetic process (ortholog); negative regulation of nitric-oxide synthase activity (ortholog); PARTICIPATES IN Fabry disease pathway; galactose metabolic pathway; GALT deficiency pathway; ASSOCIATED WITH Angiokeratoma (ortholog); angiokeratoma (ortholog); Cardiomyopathies (ortholog); FOUND IN lysosome; cytoplasm (ortholog); extracellular exosome (ortholog); INTERACTS WITH dibutyl phthalate; furan; Soman
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-galactosidase A; galactosidase, alpha (mapped); Gla_mapped
Orthologs:
Homo sapiens (human) : GLA (galactosidase alpha)  HGNC  AGR
Mus musculus (house mouse) : Gla (galactosidase, alpha)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Gla (galactosidase alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : GLA (galactosidase alpha)
Canis lupus familiaris (dog) : GLA (galactosidase alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gla (galactosidase alpha)
more info ...
Allele / Splice: Glaem2Mcwi  
Genetic Models: DA-Glaem2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X105,405,915 - 105,417,331 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X105,295,029 - 105,306,686 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X122,044,703 - 122,056,327 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX98,809,769 - 98,821,187 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gla
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589721
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE