Olr1585 (olfactory receptor 1585) - Rat Genome Database

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Gene: Olr1585 (olfactory receptor 1585) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Olr1585
Name: olfactory receptor 1585
RGD ID: 1333297
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane; INTERACTS WITH amphetamine; trichloroethene; vinclozolin.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor gene Olr1585; olfactory receptor Olr1585
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81388,579,747 - 88,595,231 (+)NCBIGRCr8
mRatBN7.21386,058,497 - 86,063,730 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1386,009,008 - 86,073,347 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1388,569,665 - 88,570,603 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01389,969,935 - 89,970,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01387,154,676 - 87,155,614 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0 Ensembl1392,103,123 - 92,123,629 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01396,631,730 - 96,632,572 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,797,359 - 89,798,297 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11389,986,242 - 89,987,181 (+)NCBI
Celera1385,664,416 - 85,665,354 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Olr1585
22 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:89
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000047706
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
1302791Stl29Serum triglyceride level QTL 293.30.0011blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)138473078886800898Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2
Low 2 2 44 30 17 30 12 7 11
Below cutoff 1 25 11 9 9 7 9 1 15 20 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004643   ⟹   ENSRNOP00000004643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1392,103,123 - 92,123,629 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096152   ⟹   ENSRNOP00000096075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1386,060,881 - 86,073,347 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116207   ⟹   ENSRNOP00000082929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1386,009,008 - 86,073,347 (+)Ensembl
RefSeq Acc Id: NM_001001109   ⟹   NP_001001109
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,594,293 - 88,595,231 (+)NCBI
mRatBN7.21386,061,957 - 86,062,895 (+)NCBI
Rnor_5.01396,631,730 - 96,632,572 (+)NCBI
RGSC_v3.41389,797,359 - 89,798,297 (+)RGD
Celera1385,664,416 - 85,665,354 (+)RGD
Sequence:
RefSeq Acc Id: XM_039090958   ⟹   XP_038946886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,579,747 - 88,595,231 (+)NCBI
mRatBN7.21386,058,497 - 86,063,730 (+)NCBI
RefSeq Acc Id: XM_063272528   ⟹   XP_063128598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,579,747 - 88,595,231 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001001109 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946886 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128598 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94752 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082929.1
  ENSRNOP00000096075
  ENSRNOP00000096075.1
Reference Protein Sequences
RefSeq Acc Id: NP_001001109   ⟸   NM_001001109
- UniProtKB: A0A8I6AP46 (UniProtKB/TrEMBL),   A6JG96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000004643   ⟸   ENSRNOT00000004643
RefSeq Acc Id: XP_038946886   ⟸   XM_039090958
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000082929   ⟸   ENSRNOT00000116207
RefSeq Acc Id: ENSRNOP00000096075   ⟸   ENSRNOT00000096152
RefSeq Acc Id: XP_063128598   ⟸   XM_063272528
- Peptide Label: isoform X1
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSL0-F1-model_v2 AlphaFold D3ZSL0 1-312 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333297 AgrOrtholog
BioCyc Gene G2FUF-17268 BioCyc
Ensembl Genes ENSRNOG00000003498 Ensembl
  ENSRNOG00000064497 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000096152 ENTREZGENE
  ENSRNOT00000096152.1 UniProtKB/TrEMBL
  ENSRNOT00000116207.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:406005 UniProtKB/TrEMBL
NCBI Gene 406005 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  ODORANT RECEPTOR-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Olr1585 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003498 RatGTEx
  ENSRNOG00000064497 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6AP46 ENTREZGENE, UniProtKB/TrEMBL
  A6JG96 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Olr1585  olfactory receptor 1585   Olr1585_predicted  olfactory receptor 1585 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1585_predicted  olfactory receptor 1585 (predicted)      Symbol and Name status set to approved 70820 APPROVED