Sgsm3 (small G protein signaling modulator 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sgsm3 (small G protein signaling modulator 3) Rattus norvegicus
Analyze
Symbol: Sgsm3
Name: small G protein signaling modulator 3
RGD ID: 735113
Description: Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in several processes, including Rap protein signal transduction; plasma membrane to endosome transport; and regulation of Rab protein signal transduction. Predicted to be located in cytosol and gap junction. Orthologous to human SGSM3 (small G protein signaling modulator 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bdif-1; hypothetical protein; RUN and TBC1 domain containing 3; RUN and TBC1 domain-containing protein 3; Rutbc3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,394,724 - 114,424,285 (+)NCBIGRCr8
mRatBN7.27112,514,453 - 112,544,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,514,630 - 112,544,108 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7114,277,198 - 114,306,669 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,500,742 - 116,530,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,470,115 - 116,499,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,203,498 - 122,232,993 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,203,532 - 122,232,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,187,850 - 122,217,330 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,259,355 - 119,306,023 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17119,293,617 - 119,340,248 (+)NCBI
Celera7108,838,288 - 108,866,794 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
gap junction  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:15709751   PMID:17509819   PMID:17562788   PMID:17646400   PMID:21453730   PMID:28716730  


Genomics

Comparative Map Data
Sgsm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,394,724 - 114,424,285 (+)NCBIGRCr8
mRatBN7.27112,514,453 - 112,544,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,514,630 - 112,544,108 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7114,277,198 - 114,306,669 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,500,742 - 116,530,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,470,115 - 116,499,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,203,498 - 122,232,993 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,203,532 - 122,232,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,187,850 - 122,217,330 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,259,355 - 119,306,023 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17119,293,617 - 119,340,248 (+)NCBI
Celera7108,838,288 - 108,866,794 (+)NCBICelera
Cytogenetic Map7q34NCBI
SGSM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,370,594 - 40,410,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,370,591 - 40,410,289 (+)EnsemblGRCh38hg38GRCh38
GRCh372240,766,598 - 40,806,293 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,096,541 - 39,136,239 (+)NCBINCBI36Build 36hg18NCBI36
Build 342239,091,094 - 39,130,793NCBI
Celera2224,568,657 - 24,608,354 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2223,729,704 - 23,769,396 (+)NCBIHuRef
CHM1_12240,725,487 - 40,765,196 (+)NCBICHM1_1
T2T-CHM13v2.02240,842,001 - 40,880,672 (+)NCBIT2T-CHM13v2.0
Sgsm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,861,966 - 80,896,491 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,861,966 - 80,896,491 (+)EnsemblGRCm39 Ensembl
GRCm381580,977,762 - 81,012,290 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,977,765 - 81,012,290 (+)EnsemblGRCm38mm10GRCm38
MGSCv371580,808,195 - 80,842,720 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,805,060 - 80,839,326 (+)NCBIMGSCv36mm8
Celera1583,098,059 - 83,132,412 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.96NCBI
Sgsm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,094,146 - 26,142,219 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,094,170 - 26,139,062 (+)NCBIChiLan1.0ChiLan1.0
SGSM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22350,216,004 - 50,247,264 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,910,482 - 52,950,196 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02221,275,464 - 21,314,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12239,094,271 - 39,411,884 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2239,402,336 - 39,411,884 (+)Ensemblpanpan1.1panPan2
SGSM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,759,714 - 24,803,333 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1024,760,162 - 24,769,478 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1024,694,730 - 24,738,134 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01025,510,076 - 25,553,515 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1025,509,954 - 25,553,470 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11025,222,399 - 25,265,776 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01025,544,643 - 25,588,214 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01025,718,961 - 25,762,365 (-)NCBIUU_Cfam_GSD_1.0
Sgsm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049458,371,633 - 8,405,658 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364921,385,347 - 1,416,124 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364921,380,322 - 1,416,060 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGSM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,968,097 - 8,017,768 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,976,015 - 8,017,782 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.255,208,551 - 5,250,235 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SGSM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,943,787 - 22,979,899 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,970,595 - 22,982,856 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045102,610,702 - 102,646,800 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgsm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247528,050,342 - 8,093,105 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247528,050,345 - 8,093,119 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sgsm3
71 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:87
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000025382
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat

Markers in Region
D7Got104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,522,128 - 112,522,356 (+)MAPPERmRatBN7.2
Rnor_6.07122,211,015 - 122,211,240NCBIRnor6.0
Rnor_5.07122,195,352 - 122,195,577UniSTSRnor5.0
RGSC_v3.47119,284,044 - 119,284,270RGDRGSC3.4
RGSC_v3.47119,284,045 - 119,284,270UniSTSRGSC3.4
RGSC_v3.17119,318,275 - 119,318,500RGD
Celera7108,845,432 - 108,845,657UniSTS
RH 3.4 Map7876.8RGD
RH 3.4 Map7876.8UniSTS
Cytogenetic Map7q34UniSTS
AI428557  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,543,635 - 112,543,805 (+)MAPPERmRatBN7.2
Rnor_6.07122,232,520 - 122,232,689NCBIRnor6.0
Rnor_5.07122,216,857 - 122,217,026UniSTSRnor5.0
RGSC_v3.47119,305,550 - 119,305,719UniSTSRGSC3.4
Celera7108,866,321 - 108,866,490UniSTS
Cytogenetic Map7q34UniSTS
AW821984  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,544,379 - 112,544,531 (+)MAPPERmRatBN7.2
Rnor_6.07122,233,264 - 122,233,415NCBIRnor6.0
Rnor_5.07122,217,601 - 122,217,752UniSTSRnor5.0
RGSC_v3.47119,306,294 - 119,306,445UniSTSRGSC3.4
Celera7108,867,065 - 108,867,216UniSTS
Cytogenetic Map7q34UniSTS
RH131243  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,543,882 - 112,544,063 (+)MAPPERmRatBN7.2
Rnor_6.07122,232,767 - 122,232,947NCBIRnor6.0
Rnor_5.07122,217,104 - 122,217,284UniSTSRnor5.0
RGSC_v3.47119,305,797 - 119,305,977UniSTSRGSC3.4
Celera7108,866,568 - 108,866,748UniSTS
RH 3.4 Map7876.7UniSTS
Cytogenetic Map7q34UniSTS
Sgsm3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,540,425 - 112,541,293 (+)MAPPERmRatBN7.2
Rnor_6.07122,229,310 - 122,230,177NCBIRnor6.0
Rnor_5.07122,213,647 - 122,214,514UniSTSRnor5.0
RGSC_v3.47119,302,340 - 119,303,207UniSTSRGSC3.4
Celera7108,863,111 - 108,863,978UniSTS
Cytogenetic Map7q34UniSTS
Sgsm3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,540,425 - 112,541,480 (+)MAPPERmRatBN7.2
Rnor_6.07122,229,310 - 122,230,364NCBIRnor6.0
Rnor_5.07122,213,647 - 122,214,701UniSTSRnor5.0
RGSC_v3.47119,302,340 - 119,303,394UniSTSRGSC3.4
Celera7108,863,111 - 108,864,165UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 6 7 2 2 5 8 70 32 36 11 5
Low 37 50 39 19 39 3 3 4 3 5 3
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_198787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB091009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM385615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB581701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000025382   ⟹   ENSRNOP00000025381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7112,514,643 - 112,544,107 (+)Ensembl
Rnor_6.0 Ensembl7122,203,532 - 122,232,991 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098829   ⟹   ENSRNOP00000079207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7112,514,634 - 112,536,313 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101805   ⟹   ENSRNOP00000080335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7112,514,630 - 112,544,108 (+)Ensembl
RefSeq Acc Id: NM_198787   ⟹   NP_942082
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,822 - 114,424,285 (+)NCBI
mRatBN7.27112,514,643 - 112,544,109 (+)NCBI
Rnor_6.07122,203,532 - 122,232,993 (+)NCBI
Rnor_5.07122,187,850 - 122,217,330 (+)NCBI
RGSC_v3.47119,259,355 - 119,306,023 (+)RGD
Celera7108,838,288 - 108,866,794 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242096   ⟹   XP_006242158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,798 - 114,424,281 (+)NCBI
mRatBN7.27112,514,453 - 112,544,109 (+)NCBI
Rnor_6.07122,203,498 - 122,232,993 (+)NCBI
Rnor_5.07122,187,850 - 122,217,330 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006242099   ⟹   XP_006242161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,724 - 114,424,281 (+)NCBI
mRatBN7.27112,514,454 - 112,543,555 (+)NCBI
Rnor_6.07122,203,498 - 122,232,993 (+)NCBI
Rnor_5.07122,187,850 - 122,217,330 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594989   ⟹   XP_017450478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,403,374 - 114,424,281 (+)NCBI
mRatBN7.27112,532,543 - 112,544,109 (+)NCBI
Rnor_6.07122,219,771 - 122,232,993 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079595   ⟹   XP_038935523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,878 - 114,424,281 (+)NCBI
mRatBN7.27112,514,909 - 112,544,109 (+)NCBI
RefSeq Acc Id: XM_063263926   ⟹   XP_063119996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,403,377 - 114,424,281 (+)NCBI
RefSeq Acc Id: XM_063263927   ⟹   XP_063119997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,395,069 - 114,424,281 (+)NCBI
RefSeq Acc Id: XM_063263928   ⟹   XP_063119998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,870 - 114,424,281 (+)NCBI
RefSeq Acc Id: XM_063263929   ⟹   XP_063119999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,798 - 114,424,281 (+)NCBI
RefSeq Acc Id: NP_942082   ⟸   NM_198787
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242158   ⟸   XM_006242096
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242161   ⟸   XM_006242099
- Peptide Label: isoform X2
- UniProtKB: A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450478   ⟸   XM_017594989
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025381   ⟸   ENSRNOT00000025382
RefSeq Acc Id: XP_038935523   ⟸   XM_039079595
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000079207   ⟸   ENSRNOT00000098829
RefSeq Acc Id: ENSRNOP00000080335   ⟸   ENSRNOT00000101805
RefSeq Acc Id: XP_063119999   ⟸   XM_063263929
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063119998   ⟸   XM_063263928
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063119997   ⟸   XM_063263927
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063119996   ⟸   XM_063263926
- Peptide Label: isoform X1
Protein Domains
Rab-GAP TBC   RUN   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P6R7-F1-model_v2 AlphaFold Q6P6R7 1-749 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695503
Promoter ID:EPDNEW_R6028
Type:initiation region
Name:Sgsm3_1
Description:small G protein signaling modulator 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07122,203,523 - 122,203,583EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735113 AgrOrtholog
BioCyc Gene G2FUF-32688 BioCyc
Ensembl Genes ENSRNOG00000018745 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025382 ENTREZGENE
  ENSRNOT00000025382.6 UniProtKB/TrEMBL
  ENSRNOT00000098829.1 UniProtKB/TrEMBL
  ENSRNOT00000101805.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.900 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599107 IMAGE-MGC_LOAD
InterPro Rab-GTPase-TBC_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Run_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SGSM3_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362963 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72600 IMAGE-MGC_LOAD
NCBI Gene 362963 ENTREZGENE
PANTHER RAB GTPASE-ACTIVATING PROTEIN 1-LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RUN AND TBC1 DOMAIN-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RabGAP-TBC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sgsm3 PhenoGen
PROSITE RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018745 RatGTEx
SMART RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZM92_RAT UniProtKB/TrEMBL
  A0A8I5ZPG8_RAT UniProtKB/TrEMBL
  A6HSY2 ENTREZGENE, UniProtKB/TrEMBL
  F1LQU9 ENTREZGENE, UniProtKB/TrEMBL
  Q6P6R7 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q76KK4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Sgsm3  small G protein signaling modulator 3  Rutbc3  RUN and TBC1 domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rutbc3  RUN and TBC1 domain containing 3  bdif-1  hypothetical protein  Symbol and Name updated 1299863 APPROVED