ONTOLOGY REPORT - ANNOTATIONS |
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Term: | neutral lipid biosynthetic process |
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Accession: | GO:0046460
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browse the term
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Definition: | The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity. |
Synonyms: | exact_synonym: | neutral lipid anabolism; neutral lipid biosynthesis; neutral lipid formation; neutral lipid synthesis |
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Dgat2 |
diacylglycerol O-acyltransferase 2 |
involved_in |
ISS ISO IEA |
GO_REF:0000024 (PMID:23066022) GO_REF:0000107 |
UniProt RGD Ensembl |
PMID:23066022 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
involved_in |
IMP |
PMID:22905194 |
UniProt |
PMID:22905194 |
RGD:30309909 |
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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Mogat1 |
monoacylglycerol O-acyltransferase 1 |
involved_in acts_upstream_of_or_within |
IBA ISO |
GO_REF:0000033 (PMID:12077311) |
GO_Central RGD |
PMID:12077311 |
GO_REF:0000033 |
NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
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Mogat2 |
monoacylglycerol O-acyltransferase 2 |
involved_in acts_upstream_of_or_within |
IBA ISO |
GO_REF:0000033 (PMID:12576479), (PMID:14966132) |
GO_Central RGD |
PMID:12576479 PMID:14966132 |
GO_REF:0000033 |
NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
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Mogat3 |
monoacylglycerol O-acyltransferase 3 |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
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Pla2g15 |
phospholipase A2, group XV |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:17626977) |
UniProt RGD |
PMID:17626977 |
GO_REF:0000024 |
NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
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Plce1 |
phospholipase C, epsilon 1 |
involved_in |
ISS ISO IEA |
GO_REF:0000024 (PMID:29058690) GO_REF:0000107 |
UniProt RGD Ensembl |
PMID:29058690 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
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Pnpla2 |
patatin-like phospholipase domain containing 2 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:23066022) |
UniProt RGD |
PMID:23066022 |
GO_REF:0000024 |
NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
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Pck1 |
phosphoenolpyruvate carboxykinase 1 |
involved_in acts_upstream_of_or_within |
IDA IBA ISO |
PMID:4186849 GO_REF:0000033 MGI:2182390 (PMID:11792850) |
GO_Central RGD |
PMID:11792850 PMID:4186849 |
GO_REF:0000033, RGD:8553288 |
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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Awat2 |
acyl-CoA wax alcohol acyltransferase 2 |
involved_in |
ISO |
(PMID:28420705) |
RGD |
PMID:28420705 |
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NCBI chr X:65,481,676...65,490,562
Ensembl chr X:65,481,929...65,527,625
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Dagla |
diacylglycerol lipase, alpha |
acts_upstream_of_or_within |
ISO |
MGI:4438719 (PMID:20147530) |
RGD |
PMID:20147530 |
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NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
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Daglb |
diacylglycerol lipase, beta |
involved_in acts_upstream_of_or_within |
IEA ISO |
GO_REF:0000107 MGI:3529581 (PMID:20147530) |
Ensembl RGD |
PMID:20147530 |
GO_REF:0000107 |
NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
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Dgat1 |
diacylglycerol O-acyltransferase 1 |
involved_in |
ISS ISO IEA |
GO_REF:0000024 (PMID:28420705) GO_REF:0000107 |
UniProt RGD Ensembl |
PMID:28420705 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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Dgat2 |
diacylglycerol O-acyltransferase 2 |
involved_in |
ISO IEA ISS |
(PMID:28420705) GO_REF:0000107 GO_REF:0000024 |
RGD Ensembl UniProt |
PMID:28420705 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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Dgat2l6 |
diacylglycerol O-acyltransferase 2-like 6 |
involved_in |
ISO |
(PMID:28420705) |
RGD |
PMID:28420705 |
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NCBI chr X:65,614,430...65,637,962
Ensembl chr X:65,614,430...65,637,962
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Mogat2 |
monoacylglycerol O-acyltransferase 2 |
involved_in |
ISO |
(PMID:28420705) |
RGD |
PMID:28420705 |
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NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
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Mogat3 |
monoacylglycerol O-acyltransferase 3 |
involved_in |
ISO |
(PMID:28420705) |
RGD |
PMID:28420705 |
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NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
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Pla2g4a |
phospholipase A2 group 4A |
involved_in |
ISO IEA ISS |
(PMID:7794891) GO_REF:0000107 GO_REF:0000024 |
RGD Ensembl UniProt |
PMID:7794891 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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Mir30c1 |
microRNA 30c-1 |
acts_upstream_of |
ISO |
(PMID:23749231) |
RGD |
PMID:23749231 |
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NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
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Mir30c2 |
microRNA 30c-2 |
acts_upstream_of |
ISO |
(PMID:23749231) |
RGD |
PMID:23749231 |
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NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
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Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
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IMP |
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RGD |
PMID:29148806 |
RGD:15042869 |
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Sik1 |
salt-inducible kinase 1 |
involved_in |
ISS ISO IEA |
GO_REF:0000024 (PMID:19244231) GO_REF:0000107 |
UniProt RGD Ensembl |
PMID:19244231 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
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Sirt1 |
sirtuin 1 |
involved_in |
ISO IEA |
(PMID:29765047) GO_REF:0000107 |
RGD Ensembl |
PMID:29765047 |
GO_REF:0000107 |
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Tmx1 |
thioredoxin-related transmembrane protein 1 |
involved_in |
ISO |
(PMID:37648867) |
RGD |
PMID:37648867 |
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NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301
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Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
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IDA |
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RGD |
PMID:16263710 |
RGD:2312807 |
NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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Apoc3 |
apolipoprotein C3 |
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IMP |
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RGD |
PMID:23542898 |
RGD:10054091 |
NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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Cnep1r1 |
CTD nuclear envelope phosphatase 1 regulatory subunit 1 |
involved_in |
ISO |
(PMID:22134922) |
RGD |
PMID:22134922 |
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NCBI chr19:18,932,631...18,947,667
Ensembl chr19:18,932,682...18,947,667
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Ctdnep1 |
CTD nuclear envelope phosphatase 1 |
involved_in |
ISO IEA ISS |
(PMID:22134922) GO_REF:0000107 GO_REF:0000024 |
RGD Ensembl UniProt |
PMID:22134922 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781
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Dgat1 |
diacylglycerol O-acyltransferase 1 |
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IMP |
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RGD |
PMID:23449193 |
RGD:10400846 |
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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Dgat2 |
diacylglycerol O-acyltransferase 2 |
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IMP |
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RGD |
PMID:17526931 |
RGD:10400884 |
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
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IDA |
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RGD |
PMID:15598672 |
RGD:2313665 |
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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Gpld1 |
glycosylphosphatidylinositol specific phospholipase D1 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:16219662) |
UniProt RGD |
PMID:16219662 |
GO_REF:0000024 |
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
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Kat5 |
lysine acetyltransferase 5 |
involved_in |
ISS IEA ISO |
GO_REF:0000024 GO_REF:0000107 (PMID:29765047) |
UniProt Ensembl RGD |
PMID:29765047 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
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Ldlr |
low density lipoprotein receptor |
involved_in |
IEA ISO |
GO_REF:0000107 (PMID:18175806) |
Ensembl RGD |
PMID:18175806 |
GO_REF:0000107 |
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Mfsd2a |
MFSD2 lysolipid transporter A, lysophospholipid |
acts_upstream_of_or_within |
ISO |
(PMID:23209793) |
RGD |
PMID:23209793 |
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NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
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Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
involved_in |
ISO IEA |
(PMID:17186944) GO_REF:0000107 |
RGD Ensembl |
PMID:17186944 |
GO_REF:0000107 |
NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
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Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
involved_in |
ISO IEA |
(PMID:17693624) GO_REF:0000107 |
RGD Ensembl |
PMID:17693624 |
GO_REF:0000107 |
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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Plin5 |
perilipin 5 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:17130488), (PMID:21885430), (PMID:22532565) |
UniProt RGD |
PMID:17130488 PMID:21885430 PMID:22532565 |
GO_REF:0000024 |
NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
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Rgn |
regucalcin |
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IDA |
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RGD |
PMID:16817230 |
RGD:9590221 |
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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Scarb1 |
scavenger receptor class B, member 1 |
involved_in |
IEA ISO |
GO_REF:0000107 (PMID:18175806) |
Ensembl RGD |
PMID:18175806 |
GO_REF:0000107 |
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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Slc27a1 |
solute carrier family 27 member 1 |
involved_in |
ISS ISO IEA |
GO_REF:0000024 (PMID:12235169) GO_REF:0000107 |
UniProt RGD Ensembl |
PMID:12235169 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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Srebf1 |
sterol regulatory element binding transcription factor 1 |
involved_in acts_upstream_of_or_within |
ISS ISO |
GO_REF:0000024 (PMID:19244231) MGI:2177959 (PMID:16046411) |
UniProt RGD |
PMID:16046411 PMID:19244231 |
GO_REF:0000024 |
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Tcf7l2 |
transcription factor 7 like 2 |
acts_upstream_of_or_within |
ISO |
MGI:1926344 (PMID:23260145) |
RGD |
PMID:23260145 |
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NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
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Avil |
advillin |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:29058690) |
UniProt RGD |
PMID:29058690 |
GO_REF:0000024 |
NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
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C3 |
complement C3 |
involved_in |
IEA ISS ISO |
GO_REF:0000107 GO_REF:0000024 (PMID:10432298) |
Ensembl UniProt RGD |
PMID:10432298 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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Fitm2 |
fat storage-inducing transmembrane protein 2 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:18160536) |
UniProt RGD |
PMID:18160536 |
GO_REF:0000024 |
NCBI chr 3:152,141,346...152,147,858
Ensembl chr 3:152,141,346...152,147,858
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Thrsp |
thyroid hormone responsive |
involved_in |
ISO IEA |
(PMID:15890771) GO_REF:0000107 |
RGD Ensembl |
PMID:15890771 |
GO_REF:0000107 |
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
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IGI |
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RGD |
PMID:16466685 |
RGD:2312800 |
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
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IGI |
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RGD |
PMID:16466685 |
RGD:2312800 |
NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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Acsl6 |
acyl-CoA synthetase long-chain family member 6 |
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IGI |
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RGD |
PMID:16466685 |
RGD:2312800 |
NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
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Agmo |
alkylglycerol monooxygenase |
involved_in |
ISO |
(PMID:35537527) |
RGD |
PMID:35537527 |
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NCBI chr 6:53,986,236...54,317,838
Ensembl chr 6:53,986,292...54,317,623
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Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
involved_in |
ISO |
MGI:1915643 (PMID:16495223), (PMID:19187773) |
RGD |
PMID:16495223 PMID:19187773 |
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NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
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Dgat1 |
diacylglycerol O-acyltransferase 1 |
involved_in acts_upstream_of_or_within |
IDA ISO IBA IEA |
(PMID:10802663), (PMID:11481335), (PMID:14668353) GO_REF:0000033 GO_REF:0000107 GO_REF:0000002 (PMID:18458083) (PMID:18238778), (PMID:32433610), (PMID:32433611) |
RGD GO_Central Ensembl InterPro |
PMID:10802663 PMID:11481335 PMID:14668353 PMID:18238778 PMID:18458083 PMID:32433610 PMID:32433611 PMID:14596837 More...
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GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1625586 |
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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Dgat2 |
diacylglycerol O-acyltransferase 2 |
involved_in acts_upstream_of_or_within |
ISO IBA IEA ISS |
(PMID:11481335), (PMID:27184406) (PMID:21680734) MGI:3037903 (PMID:11481335), (PMID:12077311), (PMID:14668353) GO_REF:0000033 GO_REF:0000107 GO_REF:0000041 GO_REF:0000024 |
RGD GO_Central Ensembl UniProt |
PMID:11481335 PMID:12077311 PMID:14668353 PMID:21680734 PMID:27184406 |
GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 |
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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Gk |
glycerol kinase |
involved_in |
ISO |
MGI:2429928 (PMID:9302256) |
RGD |
PMID:9302256 |
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NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
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Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
involved_in |
IEA IBA ISO |
GO_REF:0000107 GO_REF:0000033 MGI:2669956 (PMID:12417724), (PMID:23908354) (PMID:18238778) |
Ensembl GO_Central RGD |
PMID:12417724 PMID:18238778 PMID:23908354 |
GO_REF:0000033 GO_REF:0000107 |
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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Gpat2 |
glycerol-3-phosphate acyltransferase 2, mitochondrial |
acts_upstream_of_or_within involved_in |
ISO IBA |
(PMID:17689486) GO_REF:0000033 |
RGD GO_Central |
PMID:17689486 |
GO_REF:0000033 |
NCBI chr 3:114,646,446...114,657,051
Ensembl chr 3:114,648,498...114,657,051
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Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
involved_in |
ISO ISS IEA |
(PMID:17170135) GO_REF:0000024 GO_REF:0000041 |
RGD UniProt |
PMID:17170135 |
GO_REF:0000024 GO_REF:0000041 |
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
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Gpat4 |
glycerol-3-phosphate acyltransferase 4 |
NOT|involved_in |
ISO |
(PMID:18238778) (PMID:16436371) |
RGD |
PMID:16436371 PMID:18238778 |
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NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901
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Lpgat1 |
lysophosphatidylglycerol acyltransferase 1 |
involved_in |
ISO |
(PMID:20018982) |
RGD |
PMID:20018982 |
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NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
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Lpin1 |
lipin 1 |
involved_in |
ISO IBA |
(PMID:29765047) (PMID:24133206) GO_REF:0000033 |
RGD GO_Central |
PMID:24133206 PMID:29765047 |
GO_REF:0000033 |
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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Lpin2 |
lipin 2 |
involved_in |
IBA ISO |
GO_REF:0000033 (PMID:19136718) |
GO_Central RGD |
PMID:19136718 |
GO_REF:0000033 |
NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
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Lpin3 |
lipin 3 |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
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Lpl |
lipoprotein lipase |
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IMP |
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RGD |
PMID:11788374 |
RGD:70246 |
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Mogat1 |
monoacylglycerol O-acyltransferase 1 |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
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G |
Mogat2 |
monoacylglycerol O-acyltransferase 2 |
involved_in acts_upstream_of_or_within |
IBA ISO |
GO_REF:0000033 (PMID:12576479) (PMID:14966132) |
GO_Central RGD |
PMID:12576479 PMID:14966132 |
GO_REF:0000033 |
NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
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G |
Mogat3 |
monoacylglycerol O-acyltransferase 3 |
involved_in |
ISO IBA |
(PMID:27184406) GO_REF:0000033 |
RGD GO_Central |
PMID:27184406 |
GO_REF:0000033 |
NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
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G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
involved_in |
ISO |
(PMID:15364929), (PMID:22560221) (PMID:22560221) |
RGD |
PMID:15364929 PMID:22560221 |
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NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
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G |
Tmem68 |
transmembrane protein 68 |
involved_in |
ISO |
(PMID:37648867) |
RGD |
PMID:37648867 |
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NCBI chr 5:16,494,054...16,524,842
Ensembl chr 5:16,494,276...16,524,569
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Term paths to the root
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