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ONTOLOGY REPORT - ANNOTATIONS


Term:neutral lipid biosynthetic process
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Accession:GO:0046460 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.
Synonyms:exact_synonym: neutral lipid anabolism;   neutral lipid biosynthesis;   neutral lipid formation;   neutral lipid synthesis



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diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:23066022)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23066022 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in IMP PMID:22905194 UniProt PMID:22905194 RGD:30309909 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:12077311)
GO_Central
RGD
PMID:12077311 GO_REF:0000033 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:12576479), (PMID:14966132)
GO_Central
RGD
PMID:12576479 PMID:14966132 GO_REF:0000033 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in ISS
ISO
GO_REF:0000024
(PMID:17626977)
UniProt
RGD
PMID:17626977 GO_REF:0000024 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:29058690)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23066022)
UniProt
RGD
PMID:23066022 GO_REF:0000024 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within
IDA
IBA
ISO
PMID:4186849
GO_REF:0000033
MGI:2182390 (PMID:11792850)
GO_Central
RGD
PMID:11792850 PMID:4186849 GO_REF:0000033, RGD:8553288 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
monoacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Awat2 acyl-CoA wax alcohol acyltransferase 2 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr  X:65,481,676...65,490,562
Ensembl chr  X:65,481,929...65,527,625
JBrowse link
G Dagla diacylglycerol lipase, alpha acts_upstream_of_or_within ISO MGI:4438719 (PMID:20147530) RGD PMID:20147530 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3529581 (PMID:20147530)
Ensembl
RGD
PMID:20147530 GO_REF:0000107 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28420705)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28420705 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in ISO
IEA
ISS
(PMID:28420705)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:28420705 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dgat2l6 diacylglycerol O-acyltransferase 2-like 6 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr  X:65,614,430...65,637,962
Ensembl chr  X:65,614,430...65,637,962
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
JBrowse link
G Pla2g4a phospholipase A2 group 4A involved_in ISO
IEA
ISS
(PMID:7794891)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:7794891 GO_REF:0000024 GO_REF:0000107 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir30c1 microRNA 30c-1 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
JBrowse link
G Mir30c2 microRNA 30c-2 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IMP RGD PMID:29148806 RGD:15042869 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19244231)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19244231 GO_REF:0000024 GO_REF:0000107 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA
(PMID:29765047)
GO_REF:0000107
RGD
Ensembl
PMID:29765047 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in ISO (PMID:37648867) RGD PMID:37648867 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301
JBrowse link
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 IDA RGD PMID:16263710 RGD:2312807 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Apoc3 apolipoprotein C3 IMP RGD PMID:23542898 RGD:10054091 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 involved_in ISO (PMID:22134922) RGD PMID:22134922 NCBI chr19:18,932,631...18,947,667
Ensembl chr19:18,932,682...18,947,667
JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 involved_in ISO
IEA
ISS
(PMID:22134922)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22134922 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:23449193 RGD:10400846 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial IDA RGD PMID:15598672 RGD:2313665 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
ISO
GO_REF:0000024
(PMID:16219662)
UniProt
RGD
PMID:16219662 GO_REF:0000024 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:29765047)
UniProt
Ensembl
RGD
PMID:29765047 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
(PMID:18175806)
Ensembl
RGD
PMID:18175806 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within ISO (PMID:23209793) RGD PMID:23209793 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO
IEA
(PMID:17186944)
GO_REF:0000107
RGD
Ensembl
PMID:17186944 GO_REF:0000107 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:17693624)
GO_REF:0000107
RGD
Ensembl
PMID:17693624 GO_REF:0000107 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:17130488), (PMID:21885430), (PMID:22532565)
UniProt
RGD
PMID:17130488 PMID:21885430 PMID:22532565 GO_REF:0000024 NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
JBrowse link
G Rgn regucalcin IDA RGD PMID:16817230 RGD:9590221 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:18175806)
Ensembl
RGD
PMID:18175806 GO_REF:0000107 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12235169)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12235169 GO_REF:0000024 GO_REF:0000107 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:19244231)
MGI:2177959 (PMID:16046411)
UniProt
RGD
PMID:16046411 PMID:19244231 GO_REF:0000024 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (PMID:23260145) RGD PMID:23260145 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
regulation of diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avil advillin involved_in ISS
ISO
GO_REF:0000024
(PMID:29058690)
UniProt
RGD
PMID:29058690 GO_REF:0000024 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:10432298)
Ensembl
UniProt
RGD
PMID:10432298 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:18160536)
UniProt
RGD
PMID:18160536 GO_REF:0000024 NCBI chr 3:152,141,346...152,147,858
Ensembl chr 3:152,141,346...152,147,858
JBrowse link
G Thrsp thyroid hormone responsive involved_in ISO
IEA
(PMID:15890771)
GO_REF:0000107
RGD
Ensembl
PMID:15890771 GO_REF:0000107 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 IGI RGD PMID:16466685 RGD:2312800 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 IGI RGD PMID:16466685 RGD:2312800 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IGI RGD PMID:16466685 RGD:2312800 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Agmo alkylglycerol monooxygenase involved_in ISO (PMID:35537527) RGD PMID:35537527 NCBI chr 6:53,986,236...54,317,838
Ensembl chr 6:53,986,292...54,317,623
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 involved_in ISO MGI:1915643 (PMID:16495223), (PMID:19187773) RGD PMID:16495223 PMID:19187773 NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IBA
IEA
(PMID:10802663), (PMID:11481335), (PMID:14668353)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:18458083)
(PMID:18238778), (PMID:32433610), (PMID:32433611)
RGD
GO_Central
Ensembl
InterPro
PMID:10802663 PMID:11481335 PMID:14668353 PMID:18238778 PMID:18458083 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1625586 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
ISS
(PMID:11481335), (PMID:27184406)
(PMID:21680734)
MGI:3037903 (PMID:11481335), (PMID:12077311), (PMID:14668353)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:11481335 PMID:12077311 PMID:14668353 PMID:21680734 PMID:27184406 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Gk glycerol kinase involved_in ISO MGI:2429928 (PMID:9302256) RGD PMID:9302256 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
MGI:2669956 (PMID:12417724), (PMID:23908354)
(PMID:18238778)
Ensembl
GO_Central
RGD
PMID:12417724 PMID:18238778 PMID:23908354 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:17689486)
GO_REF:0000033
RGD
GO_Central
PMID:17689486 GO_REF:0000033 NCBI chr 3:114,646,446...114,657,051
Ensembl chr 3:114,648,498...114,657,051
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 involved_in ISO
ISS
IEA
(PMID:17170135)
GO_REF:0000024
GO_REF:0000041
RGD
UniProt
PMID:17170135 GO_REF:0000024 GO_REF:0000041 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 NOT|involved_in ISO (PMID:18238778)
(PMID:16436371)
RGD PMID:16436371 PMID:18238778 NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 involved_in ISO (PMID:20018982) RGD PMID:20018982 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Lpin1 lipin 1 involved_in ISO
IBA
(PMID:29765047)
(PMID:24133206)
GO_REF:0000033
RGD
GO_Central
PMID:24133206 PMID:29765047 GO_REF:0000033 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lpin2 lipin 2 involved_in IBA
ISO
GO_REF:0000033
(PMID:19136718)
GO_Central
RGD
PMID:19136718 GO_REF:0000033 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
JBrowse link
G Lpin3 lipin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
JBrowse link
G Lpl lipoprotein lipase IMP RGD PMID:11788374 RGD:70246 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:12576479)
(PMID:14966132)
GO_Central
RGD
PMID:12576479 PMID:14966132 GO_REF:0000033 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 involved_in ISO
IBA
(PMID:27184406)
GO_REF:0000033
RGD
GO_Central
PMID:27184406 GO_REF:0000033 NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 involved_in ISO (PMID:15364929), (PMID:22560221)
(PMID:22560221)
RGD PMID:15364929 PMID:22560221 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Tmem68 transmembrane protein 68 involved_in ISO (PMID:37648867) RGD PMID:37648867 NCBI chr 5:16,494,054...16,524,842
Ensembl chr 5:16,494,276...16,524,569
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11949
        biosynthetic process 8469
          lipid biosynthetic process 723
            neutral lipid biosynthetic process 58
              acylglycerol biosynthetic process + 58
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11949
        primary metabolic process 10579
          lipid metabolic process 1452
            neutral lipid metabolic process 150
              neutral lipid biosynthetic process 58
                acylglycerol biosynthetic process + 58
paths to the root