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ONTOLOGY REPORT - ANNOTATIONS


Term:acylglycerol biosynthetic process
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Accession:GO:0046463 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
Synonyms:exact_synonym: acylglycerol anabolism;   acylglycerol biosynthesis;   acylglycerol formation;   acylglycerol synthesis


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diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ang angiogenin ISO (PMID:2457905) RGD PMID:2457905 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISS
ISO
GO_REF:0000024
(MGI:MGI:5465510|PMID:23066022)
UniProt
RGD
PMID:23066022 GO_REF:0000024, MGI:MGI:5465510 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial IMP PMID:22905194 UniProt PMID:22905194 RGD:30309909 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G LOC100911615 patatin-like phospholipase domain-containing protein 2-like ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:213,997,721...214,002,811
Ensembl chr 1:213,997,709...214,002,815
Ensembl chr 1:213,997,709...214,002,815
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 ISO
IBA
(MGI:MGI:2181469|PMID:12077311)
PMID:21873635
RGD PMID:12077311, PMID:21873635 MGI:MGI:2181469, RGD:13792537 NCBI chr 9:84,405,481...84,418,657
Ensembl chr 9:84,405,477...84,418,591
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 ISO
IBA
(MGI:MGI:2656067|PMID:12576479), (MGI:MGI:3040558|PMID:14966132)
PMID:21873635
RGD PMID:12576479, PMID:14966132, PMID:21873635 MGI:MGI:2656067, MGI:MGI:3040558, RGD:13792537 NCBI chr 1:164,181,762...164,205,222
Ensembl chr 1:164,181,764...164,205,222
JBrowse link
G Pla2g15 phospholipase A2, group XV ISS
ISO
GO_REF:0000024
(MGI:MGI:6392937|PMID:17626977)
UniProt
RGD
PMID:17626977 GO_REF:0000024, MGI:MGI:6392937 NCBI chr19:38,129,666...38,146,958
Ensembl chr19:38,129,584...38,146,956
JBrowse link
G Plce1 phospholipase C, epsilon 1 ISS
ISO
IEA
GO_REF:0000024
(PMID:29058690)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29058690 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 ISS
ISO
GO_REF:0000024
(MGI:MGI:5465510|PMID:23066022)
UniProt
RGD
PMID:23066022 GO_REF:0000024, MGI:MGI:5465510 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pck1 phosphoenolpyruvate carboxykinase 1 IDA
ISO
IBA
PMID:4186849
MGI:MGI:2182390 (MGI:MGI:2157262|PMID:11792850)
PMID:21873635
RGD PMID:11792850, PMID:4186849, PMID:21873635 MGI:MGI:2157262, RGD:8553288, RGD:13792537 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
monoacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Awat2 acyl-CoA wax alcohol acyltransferase 2 ISO (PMID:28420705) RGD PMID:28420705 NCBI chr  X:70,224,761...70,233,021
Ensembl chr  X:70,224,654...70,270,693
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:MGI:5906070|PMID:28420705)
(PMID:28420705)
UniProt
Ensembl
RGD
PMID:28420705 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5906070 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISS
ISO
GO_REF:0000024
(PMID:28420705)
UniProt
RGD
PMID:28420705 GO_REF:0000024 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dgat2l6 diacylglycerol O-acyltransferase 2-like 6 ISO (PMID:28420705) RGD PMID:28420705 NCBI chr  X:70,354,357...70,377,887
Ensembl chr  X:70,354,360...70,377,825
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 ISO (PMID:28420705) RGD PMID:28420705 NCBI chr 1:164,181,762...164,205,222
Ensembl chr 1:164,181,764...164,205,222
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 ISO (PMID:28420705) RGD PMID:28420705 NCBI chr12:22,708,622...22,710,787
Ensembl chr12:22,708,708...22,710,674
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:7794891)
Ensembl
UniProt
RGD
PMID:7794891 GO_REF:0000024, GO_REF:0000107 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IMP RGD PMID:29148806 RGD:15042869 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Sik1 salt-inducible kinase 1 ISO
ISS
(MGI:MGI:5294536|PMID:19244231)
GO_REF:0000024
RGD
UniProt
PMID:19244231 GO_REF:0000024, MGI:MGI:5294536 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 IDA RGD PMID:16263710 RGD:2312807 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Apoc3 apolipoprotein C3 IMP RGD PMID:23542898 RGD:10054091 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 ISO (PMID:22134922) RGD PMID:22134922 NCBI chr19:19,899,306...19,913,605
Ensembl chr19:19,899,306...19,913,605
JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 ISO
ISS
(PMID:22134922)
GO_REF:0000024
RGD
UniProt
PMID:22134922 GO_REF:0000024 NCBI chr10:56,590,822...56,600,235
Ensembl chr10:56,591,292...56,600,232
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:23449193 RGD:10400846 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial IDA RGD PMID:15598672 RGD:2313665 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 ISO
ISS
(MGI:MGI:3617276|PMID:16219662)
GO_REF:0000024
RGD
UniProt
PMID:16219662 GO_REF:0000024, MGI:MGI:3617276 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Ldlr low density lipoprotein receptor ISO
IEA
(MGI:MGI:3784112|PMID:18175806)
GO_REF:0000107
RGD
Ensembl
PMID:18175806 GO_REF:0000107, MGI:MGI:3784112 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A ISO (MGI:MGI:5474727|PMID:23209793) RGD PMID:23209793 MGI:MGI:5474727 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 ISO (PMID:17186944) RGD PMID:17186944 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Plin5 perilipin 5 ISS
ISO
GO_REF:0000024
(MGI:MGI:3709110|PMID:17130488), (MGI:MGI:5440401|PMID:22532565), (MGI:MGI:5559666|PMID:21885430)
UniProt
RGD
PMID:17130488, PMID:21885430, PMID:22532565 GO_REF:0000024, MGI:MGI:3709110, MGI:MGI:5440401, MGI:MGI:5559666 NCBI chr 9:10,956,013...10,961,782
Ensembl chr 9:10,956,056...10,961,782
JBrowse link
G Rgn regucalcin IDA RGD PMID:16817230 RGD:9590221 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO (MGI:MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:MGI:3784112 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Slc27a1 solute carrier family 27 member 1 ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:6154651|PMID:12235169)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12235169 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6154651 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 ISS
ISO
GO_REF:0000024
MGI:MGI:2177959 (MGI:MGI:3603730|PMID:16046411), (MGI:MGI:5294536|PMID:19244231)
UniProt
RGD
PMID:16046411, PMID:19244231 GO_REF:0000024, MGI:MGI:3603730, MGI:MGI:5294536 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO MGI:MGI:1926344 (MGI:MGI:5468191|PMID:23260145) RGD PMID:23260145 MGI:MGI:5468191 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
regulation of diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avil advillin ISS
ISO
GO_REF:0000024
(PMID:29058690)
UniProt
RGD
PMID:29058690 GO_REF:0000024 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588
JBrowse link
regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 IDA RGD PMID:21715287 RGD:38599010 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:10432298)
Ensembl
UniProt
RGD
PMID:10432298 GO_REF:0000024, GO_REF:0000107 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 ISO
ISS
(MGI:MGI:3772596|PMID:18160536)
GO_REF:0000024
RGD
UniProt
PMID:18160536 GO_REF:0000024, MGI:MGI:3772596 NCBI chr 3:159,856,994...159,863,506
Ensembl chr 3:159,856,994...159,863,506
JBrowse link
G Thrsp thyroid hormone responsive IEA
ISO
GO_REF:0000107
(MGI:MGI:3769289|PMID:15890771)
Ensembl
RGD
PMID:15890771 GO_REF:0000107, MGI:MGI:3769289 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 IGI RGD PMID:16466685 RGD:2312800 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 IGI RGD PMID:16466685 RGD:2312800 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IGI RGD PMID:16466685 RGD:2312800 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IDA
ISO
IBA
IEA
(MGI:MGI:1855734|PMID:10802663), (MGI:MGI:2151970|PMID:11481335), (MGI:MGI:3036977|PMID:14668353)
(PMID:18238778), (PMID:18458083), (PMID:32433610), (PMID:32433611)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:10802663, PMID:11481335, PMID:14668353, PMID:18238778, PMID:18458083, PMID:32433610, PMID:32433611, PMID:14596837, PMID:21873635 GO_REF:0000107, MGI:MGI:1855734, MGI:MGI:2151970, MGI:MGI:3036977, RGD:1625586, RGD:13792537 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IEA
IBA
ISO
ISS
GO_REF:0000041
PMID:21873635
(PMID:11481335), (PMID:27184406)
GO_REF:0000024
MGI:MGI:3037903 (MGI:MGI:2151970|PMID:11481335), (MGI:MGI:2181469|PMID:12077311), (MGI:MGI:3036977|PMID:14668353)
UniProt
RGD
PMID:11481335, PMID:12077311, PMID:14668353, PMID:27184406, PMID:21873635 GO_REF:0000024, GO_REF:0000041, MGI:MGI:2151970, MGI:MGI:2181469, MGI:MGI:3036977, RGD:13792537 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:18238778)
Ensembl
RGD
PMID:18238778, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial ISO
IBA
(MGI:MGI:3762297|PMID:17689486)
PMID:21873635
RGD PMID:17689486, PMID:21873635 MGI:MGI:3762297, RGD:13792537 NCBI chr 3:119,949,921...120,003,090
Ensembl chr 3:119,994,537...120,003,090
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(MGI:MGI:3699028|PMID:17170135)
(PMID:17170135)
UniProt
RGD
PMID:17170135 GO_REF:0000024, GO_REF:0000041, MGI:MGI:3699028 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 NOT ISO (PMID:18238778)
(MGI:MGI:3623703|PMID:16436371)
RGD PMID:16436371, PMID:18238778 MGI:MGI:3623703 NCBI chr16:73,615,949...73,649,769
Ensembl chr16:73,615,949...73,649,767
JBrowse link
G Lpin1 lipin 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lpin2 lipin 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G Lpin3 lipin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:156,874,805...156,899,601
Ensembl chr 3:156,886,454...156,899,436
JBrowse link
G Lpl lipoprotein lipase IMP RGD PMID:11788374 RGD:70246 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:84,405,481...84,418,657
Ensembl chr 9:84,405,477...84,418,591
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 ISO (MGI:MGI:2656067|PMID:12576479) RGD PMID:12576479 MGI:MGI:2656067 NCBI chr 1:164,181,762...164,205,222
Ensembl chr 1:164,181,764...164,205,222
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 ISO
IBA
(PMID:27184406)
PMID:21873635
RGD PMID:27184406, PMID:21873635 RGD:13792537 NCBI chr12:22,708,622...22,710,787
Ensembl chr12:22,708,708...22,710,674
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO (MGI:MGI:5426312|PMID:22560221)
(PMID:15364929), (PMID:22560221)
RGD PMID:15364929, PMID:22560221 MGI:MGI:5426312 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular metabolic process 11065
        cellular biosynthetic process 6052
          glycerolipid biosynthetic process 181
            acylglycerol biosynthetic process 48
              diacylglycerol biosynthetic process + 10
              monoacylglycerol biosynthetic process 7
              triglyceride biosynthetic process + 39
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      primary metabolic process 10901
        lipid metabolic process 1378
          cellular lipid metabolic process 1057
            glycerolipid metabolic process 393
              acylglycerol metabolic process 144
                acylglycerol biosynthetic process 48
                  diacylglycerol biosynthetic process + 10
                  monoacylglycerol biosynthetic process 7
                  triglyceride biosynthetic process + 39
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.