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positive regulation of G protein-coupled receptor signaling pathway - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of G protein-coupled receptor signaling pathway
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Accession:GO:0045745 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
Synonyms:exact_synonym: positive regulation of G protein coupled receptor protein signaling pathway;   positive regulation of G protein coupled receptor protein signalling pathway;   positive regulation of GPCR protein signaling pathway;   positive regulation of GPCR protein signalling pathway;   up regulation of G-protein coupled receptor protein signaling pathway;   upregulation of G-protein coupled receptor protein signaling pathway
 narrow_synonym: activation of G-protein coupled receptor protein signaling pathway;   stimulation of G-protein coupled receptor protein signaling pathway

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positive regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:11316806) RGD PMID:11316806 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G C3 complement C3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:15833747)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15833747 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:17001303) RGD PMID:17001303 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18809670 RGD:2311559 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:15733912 RGD:1581735 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA		 (PMID:19307307)
GO_REF:0000107		 RGD
Ensembl		 PMID:19307307 GO_REF:0000107 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 involved_in IDA
IEA
ISO		 PMID:23994616
GO_REF:0000107
(PMID:23994616)		 Ensembl
RGD		 PMID:23994616 PMID:23994616 GO_REF:0000107, RGD:14697711 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15539556)		 UniProt
RGD		 PMID:15539556 GO_REF:0000024 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Klk14 kallikrein related-peptidase 14 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240 		JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in ISO
IEA		 (PMID:16885167)
GO_REF:0000107		 RGD
Ensembl		 PMID:16885167 GO_REF:0000107 NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666 		JBrowse link
G Klk6 kallikrein related-peptidase 6 involved_in ISO
IEA		 (PMID:16885167)
GO_REF:0000107		 RGD
Ensembl		 PMID:16885167 GO_REF:0000107 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Pde6g phosphodiesterase 6G involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:11502744)		 GO_Central
Ensembl
RGD		 PMID:11502744 GO_REF:0000033 GO_REF:0000107 NCBI chr10:105,721,502...105,726,150
Ensembl chr10:105,721,682...105,726,719 		JBrowse link
G Pde6h phosphodiesterase 6H involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:11502744)		 GO_Central
RGD		 PMID:11502744 GO_REF:0000033 NCBI chr 4:169,857,793...169,872,969
Ensembl chr 4:169,857,812...169,872,969 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:24732013) RGD PMID:24732013 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 acts_upstream_of_or_within ISO (PMID:12878180) RGD PMID:12878180 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO
IEA		 (PMID:21445361)
GO_REF:0000107		 RGD
Ensembl		 PMID:21445361 GO_REF:0000107 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Tmod2 tropomodulin 2 acts_upstream_of_or_within ISO MGI:2664500 (PMID:12799133) RGD PMID:12799133 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720 		JBrowse link
positive regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 involved_in ISO
IEA
IBA		 (PMID:18940592), (PMID:22389722)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:18940592 PMID:22389722 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:104,905,586...104,954,236 		JBrowse link
G Cntn2 contactin 2 acts_upstream_of_or_within ISO
IEA		 MGI:2181052 (PMID:11178983)
GO_REF:0000107		 RGD
Ensembl		 PMID:11178983 GO_REF:0000107 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA		 (PMID:17689978)
GO_REF:0000107		 RGD
Ensembl		 PMID:17689978 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684 		JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:20516643) RGD PMID:20516643 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Mir1 microRNA 1 involved_in ISO (PMID:19131648) RGD PMID:19131648 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir1a-1 microRNA 1a-1 involved_in ISO (PMID:19131648) RGD PMID:19131648 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of IMP PMID:19278978 BHF-UCL PMID:19278978 RGD:10047220 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18202135 RGD:5129138 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:20516643) RGD PMID:20516643 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 involved_in ISO
IEA		 (PMID:19329486)
GO_REF:0000107		 RGD
Ensembl		 PMID:19329486 GO_REF:0000107 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886 		JBrowse link
G Nos1 nitric oxide synthase 1 involved_in ISO
IEA		 (PMID:17242280)
GO_REF:0000107		 RGD
Ensembl		 PMID:17242280 GO_REF:0000107 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Pomc proopiomelanocortin involved_in IEA
ISO		 GO_REF:0000107
(PMID:25096581)		 Ensembl
RGD		 PMID:25096581 GO_REF:0000107 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt5 protein arginine methyltransferase 5 involved_in ISO
IEA		 UniProtKB:P14416 (PMID:26554819)
GO_REF:0000107		 RGD
Ensembl		 PMID:26554819 GO_REF:0000107 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296 		JBrowse link
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17157995 RGD:1625132 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
positive regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkca protein kinase C, alpha involved_in ISO
IEA		 (PMID:25313067)
GO_REF:0000107		 RGD
Ensembl		 PMID:25313067 GO_REF:0000107 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
positive regulation of C-C chemokine receptor CCR7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IEA		 (PMID:11602640)
GO_REF:0000107		 RGD
Ensembl		 PMID:11602640 GO_REF:0000107 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 acts_upstream_of ISO
IEA		 (PMID:17178876)
GO_REF:0000107		 RGD
Ensembl		 PMID:17178876 GO_REF:0000107 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of ISO
IEA		 (PMID:17178876)
GO_REF:0000107		 RGD
Ensembl		 PMID:17178876 GO_REF:0000107 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
positive regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav2 caveolin 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
PMID:15569306
(PMID:15569306)		 Ensembl
RGD		 PMID:15569306 PMID:15569306 GO_REF:0000107, RGD:8554731 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:1857159 (PMID:15016423) RGD PMID:15016423 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO
IEA		 (PMID:20659558)
GO_REF:0000107		 RGD
Ensembl		 PMID:20659558 GO_REF:0000107 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:27460146) RGD PMID:27460146 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
positive regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IMP RGD PMID:19014370 RGD:401938609 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A IDA RGD PMID:11257446 RGD:6907050 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA
ISO		 GO_REF:0000107
(PMID:20164183)		 Ensembl
RGD		 PMID:20164183 GO_REF:0000107 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Gpr27 G protein-coupled receptor 27 acts_upstream_of_or_within ISO (PMID:22253604) RGD PMID:22253604 NCBI chr 4:132,328,364...132,329,497
Ensembl chr 4:132,328,364...132,329,497 		JBrowse link
G Grp gastrin releasing peptide involved_in ISS
ISO		 GO_REF:0000024
(PMID:26658875)		 UniProt
RGD		 PMID:26658875 GO_REF:0000024 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:26078884) RGD PMID:26078884 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16223735) RGD PMID:16223735 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      signal transduction 7313
        G protein-coupled receptor signaling pathway 2466
          positive regulation of G protein-coupled receptor signaling pathway 46
            negative regulation of inhibitory G protein-coupled receptor phosphorylation 0
            positive regulation of adenosine receptor signaling pathway 3
            positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 6
            positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 4
            positive regulation of angiotensin-activated signaling pathway 1
            positive regulation of chemokine-mediated signaling pathway + 3
            positive regulation of dopamine receptor signaling pathway + 5
            positive regulation of octopamine or tyramine signaling pathway + 0
            positive regulation of opioid receptor signaling pathway + 2
            positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 6
            positive regulation of thrombin-activated receptor signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological process 13403
        signaling 7874
          signal transduction 7313
            regulation of signal transduction 3310
              regulation of G protein-coupled receptor signaling pathway 168
                positive regulation of G protein-coupled receptor signaling pathway 46
                  negative regulation of inhibitory G protein-coupled receptor phosphorylation 0
                  positive regulation of adenosine receptor signaling pathway 3
                  positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 6
                  positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 4
                  positive regulation of angiotensin-activated signaling pathway 1
                  positive regulation of chemokine-mediated signaling pathway + 3
                  positive regulation of dopamine receptor signaling pathway + 5
                  positive regulation of octopamine or tyramine signaling pathway + 0
                  positive regulation of opioid receptor signaling pathway + 2
                  positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 6
                  positive regulation of thrombin-activated receptor signaling pathway 0
paths to the root