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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of G protein-coupled receptor signaling pathway
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Accession:GO:0008277 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
Synonyms:exact_synonym: regulation of G protein coupled receptor protein signaling pathway;   regulation of G protein coupled receptor protein signalling pathway;   regulation of GPCR protein signaling pathway;   regulation of GPCR protein signalling pathway


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regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11175907)		 UniProt
RGD		 PMID:11175907 GO_REF:0000024 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Arrb1 arrestin, beta 1 acts_upstream_of_or_within TAS
ISO
IDA		 MGI:2157962 (PMID:11171997), (PMID:9400383) RGD PMID:9400383 PMID:11171997 PMID:12519791 PMID:1517224 PMID:14519533 RGD:1304268, RGD:631708, RGD:1304437 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 acts_upstream_of_or_within IDA
ISO		 MGI:2157960 (PMID:10617462), (PMID:11130073), (PMID:11171997) RGD PMID:10617462 PMID:11130073 PMID:11171997 PMID:1517224 RGD:631708 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:22732145) RGD PMID:22732145 NCBI chr14:1,203,380...1,217,536
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Dynlt1 dynein light chain Tctex-type 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10559191)		 UniProt
RGD		 PMID:10559191 GO_REF:0000024 NCBI chr 1:49,292,093...49,299,051
Ensembl chr 1:46,887,017...46,893,881 		JBrowse link
G ENSRNOG00000067753 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:188,085,521...188,087,074 JBrowse link
G Frmpd1 FERM and PDZ domain containing 1 involved_in ISO (PMID:18566450) RGD PMID:18566450 NCBI chr 5:59,443,076...59,545,125
Ensembl chr 5:59,443,076...59,545,080 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9826657 GO_REF:0000033, RGD:68782 NCBI chr10:62,840,165...62,854,508
Ensembl chr10:62,342,299...62,356,373 		JBrowse link
G Git2 GIT ArfGAP 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:47,490,350...47,531,232
Ensembl chr12:41,829,730...41,871,097 		JBrowse link
G Gpr158 G protein-coupled receptor 158 involved_in ISO
ISS
IEA		 (PMID:36996198)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:36996198 GO_REF:0000024 GO_REF:0000107 NCBI chr17:83,777,625...84,244,428
Ensembl chr17:83,834,569...84,244,428 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 IMP RGD PMID:10559191 RGD:631950 NCBI chr 3:29,538,929...29,565,921
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:8626574 RGD:61618 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Homer2 homer scaffold protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12860966)		 Ensembl
RGD		 PMID:12860966 GO_REF:0000107 NCBI chr 1:144,968,207...145,069,022
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Itgb1 integrin subunit beta 1 IMP RGD PMID:17157995 RGD:1625132 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17157995 RGD:1625132 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1860139 (PMID:20400944)
GO_REF:0000033		 RGD
GO_Central		 PMID:20400944 GO_REF:0000033 NCBI chr15:86,214,786...86,220,725
Ensembl chr15:79,801,191...79,806,282 		JBrowse link
G Kctd12b potassium channel tetramerization domain containing 12b involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1860139 (PMID:20400944)		 GO_Central
RGD		 PMID:20400944 GO_REF:0000033 NCBI chr  X:17,643,707...17,654,820
Ensembl chr  X:17,643,615...17,654,820 		JBrowse link
G Kctd16 potassium channel tetramerization domain containing 16 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1860139 (PMID:20400944)
GO_REF:0000033		 RGD
GO_Central		 PMID:20400944 GO_REF:0000033 NCBI chr18:32,166,236...32,473,067
Ensembl chr18:32,166,861...32,491,749 		JBrowse link
G Kctd8 potassium channel tetramerization domain containing 8 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1860139 (PMID:20400944)
GO_REF:0000033		 RGD
GO_Central		 PMID:20400944 GO_REF:0000033 NCBI chr14:38,773,274...39,018,182
Ensembl chr14:38,773,634...39,017,554 		JBrowse link
G Pdc phosducin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:62,297,281...62,371,754
Ensembl chr13:62,358,196...62,371,754 		JBrowse link
G Pdcl phosducin like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:41,519,953...41,529,545
Ensembl chr 3:21,110,167...21,119,715
Ensembl chr 3:21,110,167...21,119,715 		JBrowse link
G Pde4d phosphodiesterase 4D IDA RGD PMID:12552097 RGD:629543 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Phf24 PHD finger protein 24 acts_upstream_of_or_within ISO MGI:5706936 (PMID:25242222) RGD PMID:25242222 NCBI chr 5:57,143,428...57,171,054
Ensembl chr 5:57,142,632...57,168,497 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18493969)
GO_REF:0000107		 BHF-UCL
RGD
Ensembl		 PMID:18493969 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Ramp1 receptor activity modifying protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151 		JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:86,689,148...86,690,956
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 involved_in TAS
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:9315921 GO_REF:0000002, RGD:737641 NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs11 regulator of G-protein signaling 11 TAS RGD PMID:9315921 RGD:737641 NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060 		JBrowse link
G Rgs12 regulator of G-protein signaling 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:79,940,561...80,048,637
Ensembl chr14:75,715,934...75,794,596 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro
RGD		 PMID:11976690 GO_REF:0000002 GO_REF:0000033, RGD:729762 NCBI chr17:9,254,112...9,268,233
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rgs18 regulator of G-protein signaling 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11042171)		 Ensembl
RGD		 PMID:11042171 GO_REF:0000107 NCBI chr13:56,493,134...56,516,045
Ensembl chr13:56,494,010...56,516,098 		JBrowse link
G Rgs19 regulator of G-protein signaling 19 TAS RGD PMID:9571244 RGD:737647 NCBI chr 3:189,182,041...189,190,494
Ensembl chr 3:168,804,874...168,810,097 		JBrowse link
G Rgs6 regulator of G-protein signaling 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA		 MGI:2441697 (PMID:22689652)
GO_REF:0000002		 RGD
InterPro		 PMID:22689652 PMID:10092682 GO_REF:0000002, RGD:69962 NCBI chr13:89,511,492...89,941,082
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 involved_in IDA
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:9765512 GO_REF:0000002, RGD:69964 NCBI chr10:94,696,556...94,770,387
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
G Ric8b RIC8 guanine nucleotide exchange factor B acts_upstream_of_or_within ISO (PMID:12652642) RGD PMID:12652642 NCBI chr 7:18,746,716...18,843,264
Ensembl chr 7:18,748,641...18,842,372 		JBrowse link
G Slc24a4 solute carrier family 24 member 4 acts_upstream_of ISO UniProtKB:P56450 (PMID:25096581) RGD PMID:25096581 NCBI chr 6:127,044,470...127,184,684
Ensembl chr 6:121,280,031...121,414,949 		JBrowse link
G Tub TUB bipartite transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861349 (PMID:28154160)		 Ensembl
RGD		 PMID:28154160 GO_REF:0000107 NCBI chr 1:172,386,772...172,465,791
Ensembl chr 1:162,951,931...163,026,812 		JBrowse link
G Tulp3 TUB like protein 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:20889716)
(PMID:28154160)		 RGD PMID:20889716 PMID:28154160 NCBI chr 4:163,276,583...163,318,297
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Usp20 ubiquitin specific peptidase 20 involved_in ISO
IBA		 (PMID:19424180)
GO_REF:0000033		 RGD
GO_Central		 PMID:19424180 GO_REF:0000033 NCBI chr 3:34,670,613...34,704,156
Ensembl chr 3:14,272,908...14,306,409 		JBrowse link
G Usp33 ubiquitin specific peptidase 33 involved_in ISO
IBA		 (PMID:19363159), (PMID:19424180)
GO_REF:0000033		 RGD
GO_Central		 PMID:19363159 PMID:19424180 GO_REF:0000033 NCBI chr 2:241,283,209...241,328,479
Ensembl chr 2:241,292,985...241,328,479 		JBrowse link
G Zdhhc25 zinc finger, DHHC-type containing 25 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:119,692,679...119,693,911
Ensembl chr 7:119,692,705...119,694,042 		JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO
IBA
IEA		 (PMID:19001095)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:19001095 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:122,715,111...122,773,529 		JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 involved_in ISO
IBA
IEA
ISS		 (PMID:19001095)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:19001095 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673 		JBrowse link
cross-receptor inhibition within G protein-coupled receptor heterodimer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ramp3 receptor activity modifying protein 3 involved_in ISO UniProtKB:P30988 (PMID:14722252) RGD PMID:14722252 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902 		JBrowse link
desensitization of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:12582207) RGD PMID:12582207 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Gipr gastric inhibitory polypeptide receptor IDA RGD PMID:8928774 RGD:2312614 NCBI chr 1:87,932,316...87,956,084
Ensembl chr 1:78,805,593...78,814,462 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 acts_upstream_of_or_within
involved_in		 IC
ISO
IBA
IEA
IDA
IMP		 MGI:2180127|MGI:87937 (PMID:10338466), (PMID:7761854)
GO_REF:0000033
GO_REF:0000107
(PMID:15102938)
PMID:18223549		 RGD
GO_Central
Ensembl		 PMID:7761854 PMID:10338466 PMID:15102938 PMID:1403099 PMID:18223549 More... GO_REF:0000033 GO_REF:0000107, RGD:632163, RGD:8553863, RGD:13792694, RGD:7242040 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 involved_in IC
IBA
IMP
IDA		 GO_REF:0000033 GO_Central
RGD		 PMID:1403099 PMID:8381966 PMID:20837135 GO_REF:0000033, RGD:632163, RGD:5685621, RGD:5685022 NCBI chr12:49,285,228...49,395,803
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:15166006 RGD:1598508 NCBI chr14:80,230,699...80,305,292
Ensembl chr14:76,006,218...76,080,693 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:8626574 PMID:30075183 RGD:61618, RGD:13792694 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 IDA
IMP		 RGD PMID:12810562 PMID:17908240 RGD:1299124, RGD:7242040 NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IDA PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Ly6g6e lymphocyte antigen 6 family member G6E involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:26276394)		 GO_Central
RGD		 PMID:26276394 GO_REF:0000033 NCBI chr20:3,744,999...3,749,867
Ensembl chr20:3,744,999...3,750,849 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9350980 RGD:9850278 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G protein-coupled receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn2 beclin 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:23954414)
MGI:5550535 (PMID:23954414)
UniProtKB:Q5JY77 (PMID:23954414)		 RGD PMID:23954414 NCBI chr13:87,842,980...87,892,410
Ensembl chr13:87,844,531...87,845,787 		JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:A8MW95 (PMID:23954414)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23954414 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:103,556,493...103,564,275
Ensembl chr  X:98,709,841...98,772,851 		JBrowse link
G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in ISO
IBA		 (PMID:10521508), (PMID:12582207)
GO_REF:0000033		 RGD
GO_Central		 PMID:10521508 PMID:12582207 GO_REF:0000033 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in ISO
IBA
IEA		 (PMID:10644702), (PMID:12582207)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10644702 PMID:12582207 GO_REF:0000033 GO_REF:0000107 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Dnm1 dynamin 1 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:14617818 RGD:1581465 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:18424554)		 Ensembl
RGD		 PMID:18424554 PMID:14617818 GO_REF:0000107, RGD:1581465 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G ENSRNOG00000063241 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr13:26,511,609...26,513,494 JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:12519791 RGD:1304268 NCBI chr14:80,230,699...80,305,292
Ensembl chr14:76,006,218...76,080,693 		JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 involved_in ISO (PMID:15775968) RGD PMID:15775968 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592 		JBrowse link
G Pld2 phospholipase D2 acts_upstream_of_or_within ISO (PMID:14718562) RGD PMID:14718562 NCBI chr10:55,754,957...55,772,819
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Sag S-antigen visual arrestin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:95,915,640...95,956,641
Ensembl chr 9:88,469,376...88,508,820 		JBrowse link
inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (PMID:19332541) RGD PMID:19332541 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in ISO
IBA
IEA		 (PMID:16670267)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:16670267 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrdc3 arrestin domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3877613 (PMID:21982743)		 Ensembl
RGD		 PMID:21982743 GO_REF:0000107 NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:11,137,460...11,149,978 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr13:47,708,157...47,807,389
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:21164481)
GO_REF:0000033		 RGD
GO_Central		 PMID:21164481 GO_REF:0000033 NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:134,554,696...134,655,500 		JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:12631586 RGD:13508593 NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplp1 amyloid beta precursor like protein 1 involved_in ISO (PMID:16531006) RGD PMID:16531006 NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19737927)		 UniProt
Ensembl
RGD		 PMID:19737927 GO_REF:0000024 GO_REF:0000107 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr11:43,477,382...43,489,118
Ensembl chr11:29,992,034...30,003,024 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in IEA
ISO		 GO_REF:0000107
(PMID:19252089)		 Ensembl
RGD		 PMID:19252089 GO_REF:0000107 NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in ISO (PMID:19252089) RGD PMID:19252089 NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in IEA
ISO		 GO_REF:0000107
(PMID:19252089), (PMID:20819076)		 Ensembl
RGD		 PMID:19252089 PMID:20819076 GO_REF:0000107 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9013884 RGD:9850263 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689 		JBrowse link
negative regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (PMID:30718414) RGD PMID:30718414 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Mir101-2 microRNA 101-2 involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 1:236,273,922...236,274,018
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir101a microRNA 101a involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 5:121,081,683...121,081,757
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:28972028) RGD PMID:28972028 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Padi2 peptidyl arginine deiminase 2 involved_in ISO
IEA		 (PMID:18645041)
GO_REF:0000107		 RGD
Ensembl		 PMID:18645041 GO_REF:0000107 NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:153,209,053...153,251,632 		JBrowse link
G Rnf113a1 ring finger protein 113A1 involved_in ISO (PMID:28978524) RGD PMID:28978524 NCBI chr  X:121,293,621...121,294,844
Ensembl chr  X:116,427,684...116,433,762 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (PMID:18829537) RGD PMID:18829537 NCBI chr11:24,067,869...25,108,694
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO
IEA		 (PMID:15337790)
GO_REF:0000107		 RGD
Ensembl		 PMID:15337790 GO_REF:0000107 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
negative regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:94925|MGI:99578 (PMID:12097513) RGD PMID:12097513 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:94924|MGI:99578 (PMID:12097513) RGD PMID:12097513 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Palm paralemmin involved_in ISO
IEA		 (PMID:16386234)
GO_REF:0000107		 RGD
Ensembl		 PMID:16386234 GO_REF:0000107 NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:9,886,643...9,912,555 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:21896332 RGD:13524519 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA		 (PMID:17689978)
GO_REF:0000107		 RGD
Ensembl		 PMID:17689978 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:21,228,809...21,232,228
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
negative regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO
IEA		 (PMID:15123695)
GO_REF:0000107		 RGD
Ensembl		 PMID:15123695 GO_REF:0000107 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) RGD PMID:15123695 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:10734056) RGD PMID:10734056 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20852621)		 UniProt
RGD		 PMID:20852621 GO_REF:0000024 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IDA RGD PMID:1403099 RGD:632163 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IC RGD PMID:1403099 RGD:632163 NCBI chr12:49,285,228...49,395,803
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Klk14 kallikrein related-peptidase 14 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:103,258,327...103,273,792
Ensembl chr 1:94,131,998...94,137,240 		JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315 		JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7782310) RGD PMID:7782310 NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Rgs12 regulator of G-protein signaling 12 IEP RGD PMID:9651375 RGD:69959 NCBI chr14:79,940,561...80,048,637
Ensembl chr14:75,715,934...75,794,596 		JBrowse link
G Rgs13 regulator of G-protein signaling 13 acts_upstream_of_or_within ISO (PMID:12193720) RGD PMID:12193720 NCBI chr13:58,472,604...58,505,922
Ensembl chr13:55,922,395...55,955,648 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10926822)		 UniProt
RGD		 PMID:10926822 GO_REF:0000024 NCBI chr17:9,254,112...9,268,233
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in IEP
ISO
IMP		 (PMID:19127022) RGD PMID:19127022 PMID:11968023 PMID:21798518 RGD:633858, RGD:7207364 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:21798518 PMID:9918533 RGD:7207364, RGD:7207376 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 involved_in ISO
ISS		 (PMID:36996198)
GO_REF:0000024		 RGD
UniProt		 PMID:36996198 GO_REF:0000024 NCBI chr13:89,511,492...89,941,082
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rpgrip1l Rpgrip1-like involved_in ISO (PMID:19464661) RGD PMID:19464661 NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) acts_upstream_of_or_within ISO MGI:3051976 (PMID:15159548) RGD PMID:15159548 NCBI chr10:61,188,288...61,331,591
Ensembl chr10:60,690,031...60,801,883 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta involved_in ISO
IEA
ISS		 (PMID:21224381)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21224381 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:152,659,651...152,682,105 		JBrowse link
negative regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IDA RGD PMID:34919270 RGD:401938593 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bicd1 BICD cargo adaptor 1 involved_in IMP
ISO		 PMID:20164183
(PMID:20164183)		 RGD PMID:20164183 PMID:20164183 RGD:8693367 NCBI chr 4:184,208,891...184,362,840
Ensembl chr 4:182,479,071...182,627,434 		JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26051944)		 UniProt
RGD		 PMID:26051944 GO_REF:0000024 NCBI chr 1:203,619,676...203,810,035
Ensembl chr 1:194,190,393...194,380,428 		JBrowse link
negative regulation of thrombin-activated receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA		 (PMID:25198505)
GO_REF:0000107		 RGD
Ensembl		 PMID:25198505 GO_REF:0000107 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7559487) RGD PMID:7559487 NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:12239163)
GO_REF:0000107		 RGD
Ensembl		 PMID:12239163 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
positive regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 involved_in ISO
IBA
IEA		 (PMID:18940592), (PMID:22389722)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:18940592 PMID:22389722 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:104,905,586...104,954,236 		JBrowse link
G Cntn2 contactin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2181052 (PMID:11178983)
GO_REF:0000107		 RGD
Ensembl		 PMID:11178983 GO_REF:0000107 NCBI chr13:46,497,269...46,528,112
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA		 (PMID:17689978)
GO_REF:0000107		 RGD
Ensembl		 PMID:17689978 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684 		JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:20516643)		 Ensembl
RGD		 PMID:20516643 GO_REF:0000107 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Mir1 microRNA 1 involved_in ISO (PMID:19131648) RGD PMID:19131648 NCBI chr18:2,160,327...2,160,413 JBrowse link
G Mir1a-1 microRNA 1a-1 involved_in ISO (PMID:19131648) RGD PMID:19131648 NCBI chr 3:187,864,685...187,864,769
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of IMP PMID:19278978 BHF-UCL PMID:19278978 RGD:10047220 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18202135 RGD:5129138 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:20516643)		 Ensembl
RGD		 PMID:20516643 GO_REF:0000107 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr11:43,477,382...43,489,118
Ensembl chr11:29,992,034...30,003,024 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886 		JBrowse link
G Nos1 nitric oxide synthase 1 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Pomc proopiomelanocortin involved_in IEA
ISO		 GO_REF:0000107
(PMID:25096581)		 Ensembl
RGD		 PMID:25096581 GO_REF:0000107 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt5 protein arginine methyltransferase 5 involved_in ISO UniProtKB:P14416 (PMID:26554819) RGD PMID:26554819 NCBI chr15:31,938,927...31,948,318
Ensembl chr15:27,968,910...27,978,296 		JBrowse link
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17157995 RGD:1625132 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
positive regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkca protein kinase C, alpha involved_in ISO
IEA		 (PMID:25313067)
GO_REF:0000107		 RGD
Ensembl		 PMID:25313067 GO_REF:0000107 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
positive regulation of C-C chemokine receptor CCR7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:11602640) RGD PMID:11602640 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 acts_upstream_of ISO (PMID:17178876) RGD PMID:17178876 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of
involved_in		 ISO
IEA		 (PMID:17178876)
GO_REF:0000107		 RGD
Ensembl		 PMID:17178876 GO_REF:0000107 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
positive regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav2 caveolin 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
PMID:15569306
(PMID:15569306)		 Ensembl
RGD		 PMID:15569306 PMID:15569306 GO_REF:0000107, RGD:8554731 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:1857159 (PMID:15016423) RGD PMID:15016423 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:20659558) RGD PMID:20659558 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:27460146) RGD PMID:27460146 NCBI chr19:37,938,989...37,974,887
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) RGD PMID:25639753 NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Apln apelin involved_in ISO
IDA		 (PMID:11359874) RGD PMID:11359874 PMID:11359874 RGD:12907555 NCBI chr  X:132,058,739...132,091,518
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Aplnr apelin receptor involved_in ISO (PMID:25639753) RGD PMID:25639753 NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
positive regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:11316806) RGD PMID:11316806 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G C3 complement C3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:15833747)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15833747 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:17001303) RGD PMID:17001303 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18809670 RGD:2311559 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:15733912 RGD:1581735 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (PMID:19307307) RGD PMID:19307307 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 involved_in IDA
ISO		 PMID:23994616
(PMID:23994616)		 RGD PMID:23994616 PMID:23994616 RGD:14697711 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15539556)		 UniProt
Ensembl
RGD		 PMID:15539556 GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Klk14 kallikrein related-peptidase 14 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:103,258,327...103,273,792
Ensembl chr 1:94,131,998...94,137,240 		JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:103,432,743...103,442,011
Ensembl chr 1:94,296,168...94,304,666 		JBrowse link
G Klk6 kallikrein related-peptidase 6 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:103,415,411...103,422,682
Ensembl chr 1:94,280,340...94,286,121 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Pde6g phosphodiesterase 6G involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:11502744)		 GO_Central
RGD		 PMID:11502744 GO_REF:0000033 NCBI chr10:105,721,502...105,726,150
Ensembl chr10:105,721,682...105,726,719 		JBrowse link
G Pde6h phosphodiesterase 6H involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:11502744)		 GO_Central
RGD		 PMID:11502744 GO_REF:0000033 NCBI chr 4:169,857,793...169,872,969
Ensembl chr 4:169,857,812...169,872,969 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:24732013) RGD PMID:24732013 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 acts_upstream_of_or_within ISO (PMID:12878180) RGD PMID:12878180 NCBI chr 1:217,010,183...217,015,044
Ensembl chr 1:207,587,917...207,589,213 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:21445361) RGD PMID:21445361 NCBI chr15:51,786,517...51,833,260
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Tmod2 tropomodulin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2664500 (PMID:12799133)		 Ensembl
RGD		 PMID:12799133 GO_REF:0000107 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720 		JBrowse link
positive regulation of inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
positive regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IMP RGD PMID:19014370 RGD:401938609 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A IDA RGD PMID:11257446 RGD:6907050 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA
ISO		 GO_REF:0000107
(PMID:20164183)		 Ensembl
RGD		 PMID:20164183 GO_REF:0000107 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Gpr27 G protein-coupled receptor 27 acts_upstream_of_or_within ISO (PMID:22253604) RGD PMID:22253604 NCBI chr 4:133,884,894...133,886,027
Ensembl chr 4:132,328,364...132,329,497 		JBrowse link
G Grp gastrin releasing peptide involved_in ISS
ISO		 GO_REF:0000024
(PMID:26658875)		 UniProt
RGD		 PMID:26658875 GO_REF:0000024 NCBI chr18:61,658,655...61,672,037
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:26078884) RGD PMID:26078884 NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
protein kinase C deactivation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO (PMID:24284070) RGD PMID:24284070 NCBI chr 8:129,548,431...129,843,555
Ensembl chr 8:120,670,866...120,966,924 		JBrowse link
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mrap melanocortin 2 receptor accessory protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:43,477,382...43,489,118
Ensembl chr11:29,992,034...30,003,024 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886 		JBrowse link
G Pde10a phosphodiesterase 10A acts_upstream_of_or_within ISO (PMID:18923023) RGD PMID:18923023 NCBI chr 1:54,313,343...54,765,668
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde4a phosphodiesterase 4A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18923023)		 Ensembl
RGD		 PMID:18923023 GO_REF:0000107 NCBI chr 8:27,966,978...28,029,721
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:20819076) RGD PMID:20819076 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (PMID:21291891) RGD PMID:21291891 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA		 (PMID:28679962)
GO_REF:0000107		 RGD
Ensembl		 PMID:28679962 GO_REF:0000107 NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:28679962) RGD PMID:28679962 NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk ALK receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:5700373 (PMID:17487225) RGD PMID:17487225 NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 involved_in IDA PMID:17989303 UniProt PMID:17989303 RGD:8553895 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:24464040)		 ParkinsonsUK-UCL
GO_Central
RGD		 PMID:24464040 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 involved_in IDA PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
regulation of endocannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase acts_upstream_of_or_within ISO (PMID:20657592) RGD PMID:20657592 NCBI chr15:19,289,967...19,337,500
Ensembl chr15:16,859,738...16,906,985 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:23502535)		 UniProt
RGD		 PMID:23502535 GO_REF:0000024 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Mgll monoglyceride lipase involved_in ISO (PMID:20729846) RGD PMID:20729846 NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B involved_in ISS
ISO		 GO_REF:0000024
(PMID:18439408)		 UniProt
RGD		 PMID:18439408 GO_REF:0000024 NCBI chr10:80,434,888...80,450,919
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Syp synaptophysin involved_in IDA PMID:17005904 UniProt PMID:17005904 RGD:8554727 NCBI chr  X:17,521,348...17,536,449
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
regulation of opsin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 acts_upstream_of_or_within ISO MGI:3054784|MGI:3054793 (PMID:15365173), (PMID:15365178) RGD PMID:15365173 PMID:15365178 NCBI chr10:57,154,226...57,163,455
Ensembl chr10:56,655,693...56,664,922 		JBrowse link
G Grk1 G protein-coupled receptor kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15946941)		 UniProt
Ensembl
RGD		 PMID:15946941 GO_REF:0000024 GO_REF:0000107 NCBI chr16:76,122,501...76,135,792
Ensembl chr16:76,123,842...76,135,792 		JBrowse link
termination of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs12 regulator of G-protein signaling 12 IDA RGD PMID:11130074 RGD:7207399 NCBI chr14:79,940,561...80,048,637
Ensembl chr14:75,715,934...75,794,596 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    regulation of biological process 13376
      regulation of response to stimulus 4324
        regulation of signal transduction 3279
          regulation of G protein-coupled receptor signaling pathway 166
            cross-receptor inhibition within G protein-coupled receptor heterodimer 1
            negative regulation of G protein-coupled receptor signaling pathway + 77
            positive regulation of G protein-coupled receptor signaling pathway + 45
            protein kinase C deactivation 1
            regulation of G protein-coupled receptor internalization + 6
            regulation of adenosine receptor signaling pathway + 4
            regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 25
            regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway 1
            regulation of angiotensin-activated signaling pathway + 4
            regulation of chemokine-mediated signaling pathway + 13
            regulation of dopamine receptor signaling pathway + 11
            regulation of endocannabinoid signaling pathway 3
            regulation of octopamine or tyramine signaling pathway + 0
            regulation of opioid receptor signaling pathway + 4
            regulation of opsin-mediated signaling pathway + 2
            regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 7
            regulation of thrombin-activated receptor signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        regulation of cellular process 13014
          signal transduction 7251
            regulation of signal transduction 3279
              regulation of G protein-coupled receptor signaling pathway 166
                cross-receptor inhibition within G protein-coupled receptor heterodimer 1
                negative regulation of G protein-coupled receptor signaling pathway + 77
                positive regulation of G protein-coupled receptor signaling pathway + 45
                protein kinase C deactivation 1
                regulation of G protein-coupled receptor internalization + 6
                regulation of adenosine receptor signaling pathway + 4
                regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 25
                regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway 1
                regulation of angiotensin-activated signaling pathway + 4
                regulation of chemokine-mediated signaling pathway + 13
                regulation of dopamine receptor signaling pathway + 11
                regulation of endocannabinoid signaling pathway 3
                regulation of octopamine or tyramine signaling pathway + 0
                regulation of opioid receptor signaling pathway + 4
                regulation of opsin-mediated signaling pathway + 2
                regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 7
                regulation of thrombin-activated receptor signaling pathway + 4
paths to the root