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Ontology Browser

Term:
G protein-coupled receptor signaling pathway (GO:0007186)
Annotations: Rat: (2217) Mouse: (2036) Human: (1340) Chinchilla: (466) Bonobo: (969) Dog: (1392) Squirrel: (1336) Pig: (2059)
Parent Terms Term With Siblings Child Terms
apoptotic signaling pathway +   
bile acid signaling pathway +   
calmodulin dependent kinase signaling pathway +   
carbohydrate mediated signaling +   
cell surface receptor signaling pathway +   
chloroplast-nucleus signaling pathway 
dopamine receptor signaling pathway +   
endoplasmic reticulum unfolded protein response +   
ER-nucleus signaling pathway +   
extracellular ATP signaling 
G protein-coupled receptor signaling pathway +   
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
granzyme-mediated programmed cell death signaling pathway +   
hormone-mediated signaling pathway +   
hydrogen peroxide mediated signaling pathway +  
hypoxia-inducible factor-1alpha signaling pathway +   
immune response-regulating signaling pathway +   
intracellular receptor signaling pathway +   
intracellular signal transduction +   
ligand-gated ion channel signaling pathway +   
lipoprotein particle mediated signaling +   
mitochondria-nucleus signaling pathway  
necroptotic signaling pathway  
negative regulation of signal transduction +   
neuronal signal transduction +   
opioid growth factor receptor signaling pathway 
phototransduction +   
positive regulation of signal transduction +   
postsynaptic signal transduction +   
presynaptic signal transduction +   
red or far-red light signaling pathway +   
regulation of blood pressure by chemoreceptor signaling pathway 
regulation of floral organ abscission by signal transduction +  
regulation of signal transduction +   
salicylic acid mediated signaling pathway +  
serotonin receptor signaling pathway +   
signal transduction in absence of ligand +   
signal transduction involved in cellular response to ammonium ion 
signal transduction involved in filamentous growth 
signal transduction involved in positive regulation of conjugation with cellular fusion +  
signal transduction involved in regulation of gene expression  
SMAD protein signal transduction +   
sphingolipid mediated signaling pathway +   

Synonyms
Exact Synonyms: G protein coupled receptor protein signaling pathway ;   G protein coupled receptor protein signalling pathway ;   G-protein coupled receptor protein signal transduction ;   G-protein coupled receptor signalling pathway ;   GPCR signaling pathway ;   GPCR signalling pathway
Narrow Synonyms: G-protein coupled receptor signaling pathway via GPCR dimer ;   dimeric G-protein coupled receptor signaling pathway ;   dimeric G-protein coupled receptor signalling pathway
Alternate IDs: GO:0038042
Definition Sources: GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor

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