The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
granzyme-mediated programmed cell death signaling pathway +
hormone-mediated signaling pathway +
hydrogen peroxide mediated signaling pathway
immune response-regulating signaling pathway +
intracellular signal transduction +
ligand-gated ion channel signaling pathway +
lipoprotein particle mediated signaling +
necroptotic signaling pathway
negative regulation of signal transduction +
neuronal signal transduction +
opioid growth factor receptor signaling pathway
phototransduction +
positive regulation of signal transduction +
postsynaptic signal transduction +
presynaptic signal transduction +
red or far-red light signaling pathway +
regulation of blood pressure by chemoreceptor signaling pathway
regulation of floral organ abscission by signal transduction
regulation of signal transduction +
salicylic acid mediated signaling pathway +
serotonin receptor signaling pathway +
signal transduction in absence of ligand +
signal transduction involved in cellular response to ammonium ion
signal transduction involved in filamentous growth
signal transduction involved in positive regulation of conjugation with cellular fusion +
signal transduction involved in regulation of gene expression
G protein coupled receptor protein signaling pathway
;
G protein coupled receptor protein signalling pathway
;
G-protein coupled receptor protein signal transduction
;
G-protein coupled receptor signalling pathway
;
GPCR signaling pathway
;
GPCR signalling pathway