Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:enzyme activator activity
go back to main search page
Accession:GO:0008047 term browser browse the term
Definition:Binds to and increases the activity of an enzyme.
Comment:This term should only be used in cases when the regulator directly interacts with the enzyme.
Synonyms:narrow_synonym: metalloenzyme activator activity
 alt_id: GO:0010577

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
enzyme activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5AP arachidonate 5-lipoxygenase activating protein enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 3:9,618,030...9,642,990
Ensembl chr 3:9,617,949...9,643,184 		JBrowse link
G APOA5 apolipoprotein A5 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:108,154,880...108,158,998
Ensembl chr 1:108,155,641...108,157,375 		JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO mRNA editing RGD PMID:9792439 RGD:10041038 NCBI chr11:7,696,571...7,700,424
Ensembl chr11:7,696,259...7,700,643 		JBrowse link
G APOC2 apolipoprotein C2 enables IEA InterPro GO_REF:0000002 NCBI chr 6:38,406,829...38,411,239
Ensembl chr 6:38,409,641...38,410,927 		JBrowse link
G ARL1 ADP ribosylation factor like GTPase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr11:96,662,260...96,674,662
Ensembl chr11:96,659,769...96,675,486 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator enables IEA Ensembl GO_REF:0000107 NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652 		JBrowse link
G CLPS colipase enables ISO
IEA		 RGD
InterPro		 PMID:8203536 GO_REF:0000002 RGD:728275 NCBI chr17:36,320,468...36,322,912
Ensembl chr17:36,320,541...36,322,902 		JBrowse link
G CLPSL1 colipase like 1 enables IEA InterPro GO_REF:0000002 NCBI chr17:36,327,877...36,335,320
Ensembl chr17:36,328,030...36,334,959 		JBrowse link
G CLPSL2 colipase like 2 enables IEA InterPro GO_REF:0000002 NCBI chr17:36,336,509...36,339,731
Ensembl chr17:36,336,615...36,339,416 		JBrowse link
G COX17 COX17, cytochrome c oxidase copper chaperone enables ISO (PMID:12370308) MGI PMID:12370308 NCBI chr22:61,143,400...61,151,348
Ensembl chr22:61,143,462...61,151,299 		JBrowse link
G DAD1 defender against cell death 1 enables IEA Ensembl GO_REF:0000107 NCBI chr29:22,935,231...22,958,331
Ensembl chr29:22,935,005...22,958,414 		JBrowse link
G DCP1A decapping mRNA 1A enables IEA InterPro GO_REF:0000002 NCBI chr22:14,678,611...14,735,688
Ensembl chr22:14,678,429...14,735,619 		JBrowse link
G DCP1B decapping mRNA 1B enables IEA InterPro GO_REF:0000002 NCBI chr11:1,992,583...2,057,717
Ensembl chr11:1,999,353...2,057,713 		JBrowse link
G DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit enables ISO (PMID:22467853) ARUK-UCL PMID:22467853 NCBI chr20:111,892,317...111,901,690
Ensembl chr20:111,891,793...111,901,429 		JBrowse link
G DNMT3L DNA methyltransferase 3 like enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:87,991,868...88,006,399
Ensembl chr 2:87,991,936...88,005,459 		JBrowse link
G DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory enables IEA Ensembl GO_REF:0000107 NCBI chr12:10,184,087...10,187,463
Ensembl chr12:10,185,040...10,187,279 		JBrowse link
G DPM3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory enables ISO (PMID:10835346) HGNC-UCL PMID:10835346 NCBI chr20:8,689,727...8,690,430 JBrowse link
G DPM3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory enables IEA Ensembl GO_REF:0000107 Ensembl chr20:8,689,996...8,690,358 JBrowse link
G EED embryonic ectoderm development enables IEA Ensembl GO_REF:0000107 NCBI chr 1:77,496,266...77,531,439
Ensembl chr 1:77,496,086...77,531,499 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease enables ISO (PMID:9927729) UniProt PMID:9927729 NCBI chr 3:81,406,103...81,441,422
Ensembl chr 3:81,405,872...81,436,040 		JBrowse link
G FAM47E family with sequence similarity 47 member E enables ISO (PMID:33376131) ARUK-UCL PMID:33376131 NCBI chr 7:24,750,287...24,782,574 JBrowse link
G FAM47E family with sequence similarity 47 member E enables IEA Ensembl GO_REF:0000107 Ensembl chr 7:24,755,448...24,782,779 JBrowse link
G FNIP1 folliculin interacting protein 1 enables ISO (PMID:24081491) UniProt PMID:24081491 NCBI chr23:34,443,171...34,637,797
Ensembl chr23:34,480,901...34,637,662 		JBrowse link
G GM2A GM2 ganglioside activator enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr23:53,808,447...53,831,489 JBrowse link
G GPR158 G protein-coupled receptor 158 enables ISO (MGI:5780405|PMID:25792749)
(PMID:31189666), (PMID:36996198)		 UniProt PMID:25792749 PMID:31189666 PMID:36996198 MGI:5780405 NCBI chr 9:24,903,263...25,310,817 JBrowse link
G IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta enables ISO (PMID:6853513) FlyBase PMID:6853513 NCBI chr 2:53,875,991...53,882,069
Ensembl chr 2:53,875,390...53,881,716 		JBrowse link
G IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma enables ISO (PMID:6853513) FlyBase PMID:6853513 NCBI chr  X:128,212,660...128,221,637 JBrowse link
G KRTCAP2 keratinocyte associated protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr20:8,659,239...8,666,375
Ensembl chr20:8,658,881...8,666,831 		JBrowse link
G LOC103232916 ganglioside GM2 activator enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr  X:39,308,349...39,308,823 JBrowse link
G LOC103233210 cytochrome b5 type B ISO RGD PMID:12668680 RGD:1582390 NCBI chr 5:57,939,055...57,978,240
Ensembl chr 5:57,937,176...57,978,449 		JBrowse link
G LRCOL1 leucine rich colipase like 1 enables IEA InterPro GO_REF:0000002 Ensembl chr11:127,949,214...127,951,432 JBrowse link
G LTC4S leukotriene C4 synthase enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G MGST2 microsomal glutathione S-transferase 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 7:86,629,691...86,666,912
Ensembl chr 7:86,629,642...86,666,857 		JBrowse link
G NANOS1 nanos C2HC-type zinc finger 1 enables ISO (PMID:24736845) BHF-UCL PMID:24736845 NCBI chr 9:111,823,590...111,825,389 JBrowse link
G NANOS2 nanos C2HC-type zinc finger 2 enables ISO (PMID:24736845) BHF-UCL PMID:24736845 NCBI chr 6:39,359,581...39,361,699
Ensembl chr 6:39,360,640...39,361,056 		JBrowse link
G NANOS3 nanos C2HC-type zinc finger 3 enables ISO (PMID:24736845) BHF-UCL PMID:24736845 NCBI chr 6:12,537,449...12,541,660
Ensembl chr 6:12,538,133...12,541,816 		JBrowse link
G PRKCD protein kinase C delta enables IEA Ensembl GO_REF:0000107 NCBI chr22:14,561,401...14,592,877
Ensembl chr22:14,565,282...14,592,873 		JBrowse link
G PRKCE protein kinase C epsilon enables IEA Ensembl GO_REF:0000107 NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343 		JBrowse link
G RACK1 receptor for activated C kinase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr23:82,800,211...82,805,769
Ensembl chr23:82,798,085...82,805,936 		JBrowse link
G RAMAC RNA guanine-7 methyltransferase activating subunit enables ISO (PMID:27422871) UniProt PMID:27422871 NCBI chr29:2,652,843...2,667,718 JBrowse link
G SDHAF4 succinate dehydrogenase complex assembly factor 4 enables ISO (MGI:5605436|PMID:24954416) UniProt PMID:24954416 MGI:5605436 NCBI chr17:4,410,081...4,432,885
Ensembl chr17:4,410,932...4,432,841 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO squalene monooxygenase (epoxidase) RGD PMID:11226224 RGD:727312 NCBI chr19:13,276,712...13,302,737
Ensembl chr19:13,276,913...13,305,003 		JBrowse link
G SFRP2 secreted frizzled related protein 2 enables ISO (PMID:19079247) MGI PMID:19079247 NCBI chr 7:100,336,442...100,345,093
Ensembl chr 7:100,336,119...100,345,086 		JBrowse link
G SLX4 SLX4 structure-specific endonuclease subunit enables ISO (PMID:19596235) UniProt PMID:19596235 NCBI chr 5:3,281,468...3,308,296 JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 enables ISO (MGI:5751610|PMID:26816378) UniProt PMID:26816378 MGI:5751610
G SUZ12 SUZ12 polycomb repressive complex 2 subunit enables IEA Ensembl GO_REF:0000107 NCBI chr16:25,413,928...25,474,311
Ensembl chr16:25,413,954...25,476,479 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 enables ISO (PMID:10827175)
(PMID:10827176)		 MGI PMID:10827175 PMID:10827176 NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471 		JBrowse link
G WDR4 WD repeat domain 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:86,715,939...86,745,972
Ensembl chr 2:86,716,922...86,745,547 		JBrowse link
G WRNIP1 WRN helicase interacting protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:69,366,565...69,386,950
Ensembl chr17:69,366,389...69,386,932 		JBrowse link
acetyltransferase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAS3 BCAS3 microtubule associated cell migration factor enables ISO (PMID:17505058) UniProt PMID:17505058 NCBI chr16:31,912,523...32,620,308 JBrowse link
G BRPF1 bromodomain and PHD finger containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr22:45,740,192...45,756,327
Ensembl chr22:45,740,351...45,756,390 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator enables IEA Ensembl GO_REF:0000107 NCBI chr 5:26,382,125...26,385,605
Ensembl chr 5:26,382,132...26,385,348 		JBrowse link
G PDCD5 programmed cell death 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:27,633,604...27,639,766
Ensembl chr 6:27,633,621...27,639,794 		JBrowse link
adenylate cyclase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CALM2 calmodulin 2 enables IEA Ensembl GO_REF:0000107 NCBI chr14:60,027,884...60,042,041
Ensembl chr14:60,027,801...60,044,951
Ensembl chr 6:60,027,801...60,044,951
Ensembl chr24:60,027,801...60,044,951 		JBrowse link
G CALM3 calmodulin 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:39,957,012...39,966,562
Ensembl chr 6:39,957,320...39,966,581
Ensembl chr24:39,957,320...39,966,581
Ensembl chr14:39,957,320...39,966,581 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 enables ISO PMID:13680124
(PMID:17971513)		 UniProt
MGI		 PMID:13680124 PMID:17971513 RGD:2312682 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase enables ISO PMID:15385642 BHF-UCL PMID:15385642 RGD:8554216 NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020 		JBrowse link
calcium sensitive guanylate cyclase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CIMIP3 ciliary microtubule inner protein 3 enables ISO (PMID:11493703) MGI PMID:11493703 NCBI chr17:29,987,083...29,995,791 JBrowse link
G GUCA1A guanylate cyclase activator 1A enables IEA Ensembl GO_REF:0000107 NCBI chr17:29,972,216...29,984,653
Ensembl chr17:29,972,862...29,977,487 		JBrowse link
G GUCA1B guanylate cyclase activator 1B enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:29,957,206...29,969,294
Ensembl chr17:29,957,508...29,967,922 		JBrowse link
G NCS1 neuronal calcium sensor 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr12:7,910,495...7,975,650 JBrowse link
cyclin-dependent protein kinase activating kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A enables IEA Ensembl GO_REF:0000107 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342 		JBrowse link
cyclin-dependent protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 enables ISO (PMID:24746669) CAFA PMID:24746669 NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085 		JBrowse link
G CCND1 cyclin D1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CCND2 cyclin D2 enables ISO (PMID:18827403) UniProt PMID:18827403 NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661 		JBrowse link
G CCND3 cyclin D3 enables IEA Ensembl GO_REF:0000107 NCBI chr17:30,107,236...30,228,449
Ensembl chr17:30,221,598...30,227,452 		JBrowse link
G CCNK cyclin K enables IEA TreeGrafter GO_REF:0000118 NCBI chr24:77,436,569...77,466,703
Ensembl chr24:77,436,479...77,467,322 		JBrowse link
G CCNT1 cyclin T1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:44,932,774...44,966,412
Ensembl chr11:44,937,350...44,966,018 		JBrowse link
G CCNT2 cyclin T2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:19,145,163...19,183,777
Ensembl chr10:19,145,161...19,180,917 		JBrowse link
G CCNY cyclin Y enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:34,626,185...34,847,835
Ensembl chr 9:34,626,323...34,848,918 		JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 enables ISO
IEA		 RGD
TreeGrafter
InterPro
Ensembl		 PMID:8662984 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:632374 NCBI chr16:26,044,751...26,048,920
Ensembl chr16:26,045,061...26,049,101 		JBrowse link
G CDK5R2 cyclin dependent kinase 5 regulatory subunit 2 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr10:104,858,260...104,860,795
Ensembl chr10:104,858,461...104,859,564 		JBrowse link
G MNAT1 MNAT1 component of CDK activating kinase enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr24:37,922,347...38,161,467
Ensembl chr24:37,922,353...38,162,226 		JBrowse link
cysteine-type endopeptidase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 enables IEA Ensembl GO_REF:0000107 NCBI chr20:4,759,746...4,884,460
Ensembl chr20:4,873,008...4,884,764 		JBrowse link
G LOC103234962 caspase recruitment domain-containing protein 8 enables ISO (PMID:15030775), (PMID:31525884), (PMID:32840892), (PMID:33542150) UniProt PMID:15030775 PMID:31525884 PMID:32840892 PMID:33542150 NCBI chr 6:41,446,890...41,500,098 JBrowse link
G NLRP1 NLR family pyrin domain containing 1 enables ISO (PMID:22665479), (PMID:30291141), (PMID:33852854), (PMID:35594856) UniProt PMID:22665479 PMID:30291141 PMID:33852854 PMID:35594856 NCBI chr16:4,930,643...4,983,378 JBrowse link
G NLRP3 NLR family pyrin domain containing 3 enables ISO (PMID:31189953) UniProt PMID:31189953 NCBI chr25:84,431,436...84,463,387
Ensembl chr25:84,434,527...84,463,249 		JBrowse link
G TIMM50 translocase of inner mitochondrial membrane 50 enables ISO (PMID:32848200) FlyBase PMID:32848200 NCBI chr 6:34,089,043...34,098,574 JBrowse link
cysteine-type endopeptidase activator activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr11:93,942,137...94,024,728
Ensembl chr11:93,942,103...94,024,457 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 enables ISO (PMID:16725111) ARUK-UCL PMID:16725111 NCBI chr16:3,405,871...3,443,339
Ensembl chr16:3,405,820...3,443,275 		JBrowse link
G BAD BCL2 associated agonist of cell death enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432 		JBrowse link
G CASP8 caspase 8 enables ISO (PMID:9837723) MGI PMID:9837723 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CASP8AP2 caspase 8 associated protein 2 enables ISO (PMID:10235259) MGI PMID:10235259 NCBI chr13:14,586,857...14,632,384
Ensembl chr13:14,586,929...14,632,362 		JBrowse link
G CTSH cathepsin H enables ISO (PMID:20435891)
(MGI:4838939|PMID:20435891)		 UniProt PMID:20435891 MGI:4838939 NCBI chr26:4,451,731...4,473,220
Ensembl chr26:4,451,774...4,472,855 		JBrowse link
G CTSS cathepsin S enables IEA TreeGrafter GO_REF:0000118
G LOC103234965 caspase recruitment domain-containing protein 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:41,505,337...41,524,771 JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:14522843 RGD:2304239 NCBI chr23:81,965,330...82,026,414
Ensembl chr23:81,963,899...82,013,659 		JBrowse link
G NGF nerve growth factor enables ISO (PMID:11927634) ARUK-UCL PMID:11927634 NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833 		JBrowse link
G NKX3-1 NK3 homeobox 1 enables ISO (PMID:19266349) UniProt PMID:19266349 NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319 		JBrowse link
G RACK1 receptor for activated C kinase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr23:82,800,211...82,805,769
Ensembl chr23:82,798,085...82,805,936 		JBrowse link
G RPS27L ribosomal protein S27 like enables ISO (PMID:17057733) UniProt PMID:17057733 NCBI chr26:20,385,684...20,389,351 JBrowse link
deubiquitinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMWD DM1 locus, WD repeat containing enables IEA Ensembl GO_REF:0000107 NCBI chr 6:39,233,395...39,242,446
Ensembl chr 6:39,233,911...39,242,403 		JBrowse link
G TANK TRAF family member associated NFKB activator enables IEA Ensembl GO_REF:0000107 NCBI chr10:46,527,795...46,632,133
Ensembl chr10:46,556,614...46,632,186 		JBrowse link
G TGFB1 transforming growth factor beta 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365 		JBrowse link
G TIFAB TIFA inhibitor enables ISO (PMID:32101751) MGI PMID:32101751 NCBI chr23:38,228,904...38,232,892 JBrowse link
G VCP valosin containing protein enables ISO (PMID:22970133) ParkinsonsUK-UCL PMID:22970133 NCBI chr12:45,545,139...45,560,702
Ensembl chr12:45,545,507...45,563,380 		JBrowse link
G WDR20 WD repeat domain 20 enables ISO (PMID:20147737), (PMID:27373336) UniProt PMID:20147737 PMID:27373336 NCBI chr24:80,064,362...80,152,706
Ensembl chr24:80,064,421...80,152,881 		JBrowse link
G WDR48 WD repeat domain 48 enables ISO (PMID:18082604), (PMID:19075014), (PMID:24145035), (PMID:31253762) UniProt PMID:18082604 PMID:19075014 PMID:24145035 PMID:31253762 NCBI chr15:319,589...366,265
Ensembl chr15:319,810...366,246 		JBrowse link
DNA polymerase processivity factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCNA proliferating cell nuclear antigen enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit enables IEA Ensembl GO_REF:0000107 NCBI chr16:56,773,867...56,794,571
Ensembl chr16:56,776,330...56,794,654 		JBrowse link
G TEFM transcription elongation factor, mitochondrial enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:25,601,744...25,609,071
Ensembl chr16:25,601,941...25,608,209 		JBrowse link
endopeptidase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRM1 ADRM1 26S proteasome ubiquitin receptor enables IEA TreeGrafter GO_REF:0000118 NCBI chr 2:1,930,281...1,936,323
Ensembl chr 2:1,925,382...1,936,393 		JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit enables ISO (PMID:12297508)
(PMID:12763021)
(MGI:6478051|PMID:12522139)		 ARUK-UCL PMID:12297508 PMID:12522139 PMID:12763021 MGI:6478051
G APH1B aph-1 homolog B, gamma-secretase subunit enables ISO (PMID:12763021)
(PMID:12297508)		 ARUK-UCL PMID:12297508 PMID:12763021 NCBI chr26:20,236,666...20,265,167
Ensembl chr26:20,240,015...20,265,151 		JBrowse link
G LGMN legumain enables ISO (PMID:18374643) ARUK-UCL PMID:18374643 NCBI chr24:70,456,463...70,500,345
Ensembl chr24:70,456,095...70,486,087 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 enables ISO (PMID:15882992) ARUK-UCL PMID:15882992 NCBI chr14:75,229,262...75,273,336
Ensembl chr14:75,242,274...75,273,312 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit enables IEA Ensembl GO_REF:0000107 NCBI chr 6:30,655,162...30,656,587
Ensembl chr 6:30,655,243...30,656,584 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 enables IEA Ensembl GO_REF:0000107 NCBI chr10:46,703,876...46,814,938
Ensembl chr10:46,704,098...46,815,132 		JBrowse link
G PSME1 proteasome activator subunit 1 enables
contributes_to		 IEA
ISO		 (PMID:15944286) Ensembl
TreeGrafter
MGI		 PMID:15944286 GO_REF:0000107 GO_REF:0000118 NCBI chr24:1,122,086...1,124,907
Ensembl chr24:1,122,631...1,125,416 		JBrowse link
G PSME2 proteasome activator subunit 2 contributes_to ISO (PMID:15944286) MGI PMID:15944286 NCBI chr24:1,129,389...1,133,289
Ensembl chr24:1,129,419...1,132,596 		JBrowse link
G PSME3 proteasome activator subunit 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:63,449,954...63,460,490
Ensembl chr16:63,452,105...63,460,199 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 enables ISO (PMID:24305806) ARUK-UCL PMID:24305806 NCBI chr14:96,275,889...96,443,048
Ensembl chr14:96,276,023...96,432,790 		JBrowse link
G SFRP2 secreted frizzled related protein 2 enables ISO (PMID:19079247) MGI PMID:19079247 NCBI chr 7:100,336,442...100,345,093
Ensembl chr 7:100,336,119...100,345,086 		JBrowse link
G VSIR V-set immunoregulatory receptor enables ISO (PMID:20666777) UniProt PMID:20666777 NCBI chr 9:59,516,012...59,538,628
Ensembl chr 9:59,516,073...59,542,242 		JBrowse link
GTPase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABR ABR activator of RhoGEF and GTPase enables IEA Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr16:732,556...947,329
Ensembl chr16:735,211...847,690 		JBrowse link
G ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr16:6,715,240...6,729,781
Ensembl chr16:6,715,278...6,729,864 		JBrowse link
G ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 enables IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr15:89,341,026...89,516,816
Ensembl chr15:89,340,947...89,516,815 		JBrowse link
G ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr20:130,143,085...130,157,716
Ensembl chr20:130,143,520...130,157,730 		JBrowse link
G ADAP1 ArfGAP with dual PH domains 1 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr28:20,617,948...20,677,848
Ensembl chr28:20,617,995...20,680,628 		JBrowse link
G ADAP2 ArfGAP with dual PH domains 2 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr16:25,623,548...25,658,891
Ensembl chr16:25,623,786...25,657,029 		JBrowse link
G ADGRB3 adhesion G protein-coupled receptor B3 enables ISO (MGI:5644012|PMID:23628982) UniProt PMID:23628982 MGI:5644012 NCBI chr17:5,543,587...6,287,255
Ensembl chr17:5,543,556...6,000,742 		JBrowse link
G AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr10:121,508,992...122,144,519
Ensembl chr10:121,719,490...122,142,090 		JBrowse link
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:53,638,722...53,655,826
Ensembl chr11:53,640,079...53,651,913 		JBrowse link
G AGFG1 ArfGAP with FG repeats 1 enables IEA InterPro GO_REF:0000002 NCBI chr10:113,500,174...113,589,243
Ensembl chr10:113,500,391...113,582,474 		JBrowse link
G AGFG2 ArfGAP with FG repeats 2 enables IEA InterPro GO_REF:0000002 NCBI chr28:12,647,383...12,674,303
Ensembl chr28:12,646,515...12,674,301 		JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 enables ISO (PMID:12837691), (PMID:15247254) MGI PMID:12837691 PMID:15247254 NCBI chr10:87,389,130...87,473,134 JBrowse link
G ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 enables IEA UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:63,923,241...63,991,221
Ensembl chr 1:63,920,076...63,960,771 		JBrowse link
G ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr27:14,036,751...14,215,997
Ensembl chr27:14,052,478...14,214,050 		JBrowse link
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 enables
NOT|enables		 IEA
ISO		 (PMID:15546919) UniProt
MGI
InterPro		 PMID:15546919 GO_REF:0000002 GO_REF:0000043 NCBI chr23:44,280,010...44,308,046
Ensembl chr23:44,279,727...44,306,272 		JBrowse link
G ARFGAP1 ADP ribosylation factor GTPase activating protein 1 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:918,508...936,175
Ensembl chr 2:917,479...936,138 		JBrowse link
G ARFGAP2 ADP ribosylation factor GTPase activating protein 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:18,136,257...18,161,083
Ensembl chr 1:18,136,519...18,148,228 		JBrowse link
G ARFGAP3 ADP ribosylation factor GTPase activating protein 3 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr19:25,339,722...25,401,119
Ensembl chr19:25,339,496...25,400,951 		JBrowse link
G ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1 NOT|enables ISO (PMID:15644318) UniProt PMID:15644318 NCBI chr 8:63,058,504...63,204,238
Ensembl chr 8:63,057,200...63,204,292 		JBrowse link
G ARHGAP1 Rho GTPase activating protein 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:18,627,534...18,648,984
Ensembl chr 1:18,627,611...18,650,706 		JBrowse link
G ARHGAP10 Rho GTPase activating protein 10 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 7:94,233,257...94,568,042
Ensembl chr 7:94,216,032...94,568,502 		JBrowse link
G ARHGAP12 Rho GTPase activating protein 12 enables IEA UniProt GO_REF:0000043 NCBI chr 9:31,124,281...31,249,546
Ensembl chr 9:31,123,727...31,249,524 		JBrowse link
G ARHGAP15 Rho GTPase activating protein 15 enables IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr10:28,493,123...29,123,849
Ensembl chr10:28,519,775...29,124,579 		JBrowse link
G ARHGAP17 Rho GTPase activating protein 17 enables IEA InterPro GO_REF:0000002 NCBI chr 5:22,634,252...22,739,810
Ensembl chr 5:22,640,686...22,703,115 		JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 enables ISO (PMID:21865595)
(PMID:25211221)		 UniProt
MGI		 PMID:21865595 PMID:25211221 NCBI chr13:43,825,469...44,015,655
Ensembl chr13:43,880,459...44,018,036 		JBrowse link
G ARHGAP19 Rho GTPase activating protein 19 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:90,396,061...90,469,716
Ensembl chr 9:90,334,674...90,469,609 		JBrowse link
G ARHGAP20 Rho GTPase activating protein 20 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:101,920,074...102,047,171
Ensembl chr 1:101,921,839...102,046,751 		JBrowse link
G ARHGAP21 Rho GTPase activating protein 21 enables IEA UniProt GO_REF:0000043 NCBI chr 9:24,325,648...24,459,006
Ensembl chr 9:24,326,454...24,406,743 		JBrowse link
G ARHGAP22 Rho GTPase activating protein 22 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:43,140,076...43,349,962
Ensembl chr 9:43,316,598...43,349,602 		JBrowse link
G ARHGAP23 Rho GTPase activating protein 23 enables IEA UniProt GO_REF:0000043 NCBI chr16:67,680,015...67,772,050
Ensembl chr16:67,680,018...67,732,938 		JBrowse link
G ARHGAP24 Rho GTPase activating protein 24 enables ISO (PMID:21911940) MGI PMID:21911940 NCBI chr 7:33,635,577...34,384,835
Ensembl chr 7:34,316,100...34,387,205 		JBrowse link
G ARHGAP25 Rho GTPase activating protein 25 enables IEA UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000118 NCBI chr14:38,297,738...38,389,692
Ensembl chr14:38,297,213...38,389,777 		JBrowse link
G ARHGAP26 Rho GTPase activating protein 26 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr23:45,399,159...45,860,331
Ensembl chr23:45,399,259...45,849,040 		JBrowse link
G ARHGAP27 Rho GTPase activating protein 27 enables ISO
IEA		 RGD
UniProt		 PMID:15147912 GO_REF:0000043 RGD:1302833 NCBI chr16:60,984,171...61,020,579
Ensembl chr16:60,985,548...61,020,220 		JBrowse link
G ARHGAP31 Rho GTPase activating protein 31 enables ISO (PMID:11744688) MGI PMID:11744688 NCBI chr22:61,415,805...61,543,679
Ensembl chr22:61,415,804...61,543,834 		JBrowse link
G ARHGAP33 Rho GTPase activating protein 33 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:30,684,679...30,697,943
Ensembl chr 6:30,684,731...30,697,556 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 enables IEA UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000118 NCBI chr 6:40,264,466...40,353,157
Ensembl chr 6:40,205,892...40,353,280 		JBrowse link
G ARHGAP39 Rho GTPase activating protein 39 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 8:138,743,479...138,886,662
Ensembl chr 8:138,743,403...138,886,602 		JBrowse link
G ARHGAP40 Rho GTPase activating protein 40 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 2:25,105,788...25,161,502
Ensembl chr 2:25,106,573...25,134,690 		JBrowse link
G ARHGAP42 Rho GTPase activating protein 42 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:92,064,404...92,384,103
Ensembl chr 1:92,065,132...92,382,915 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr16:12,125,543...12,328,203
Ensembl chr16:12,125,574...12,330,501 		JBrowse link
G ARHGAP45 Rho GTPase activating protein 45 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:823,109...842,697
Ensembl chr 6:823,154...846,070 		JBrowse link
G ARHGAP5 Rho GTPase activating protein 5 enables IEA UniProt GO_REF:0000043 NCBI chr24:8,914,485...8,986,498
Ensembl chr24:8,928,252...8,988,302 		JBrowse link
G ARHGAP8 Rho GTPase activating protein 8 enables ISO (PMID:12944407), (PMID:20179103) MGI PMID:12944407 PMID:20179103 NCBI chr19:27,238,379...27,328,338 JBrowse link
G ARHGAP9 Rho GTPase activating protein 9 enables IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr11:53,384,335...53,398,445
Ensembl chr11:53,384,449...53,396,083 		JBrowse link
G ARHGEF1 Rho guanine nucleotide exchange factor 1 enables IEA InterPro GO_REF:0000002 NCBI chr 6:36,091,158...36,115,355
Ensembl chr 6:36,091,204...36,115,626 		JBrowse link
G ARHGEF10L Rho guanine nucleotide exchange factor 10 like enables IEA Ensembl GO_REF:0000107 NCBI chr20:114,877,880...115,059,252
Ensembl chr20:114,878,369...114,987,595 		JBrowse link
G ARHGEF12 Rho guanine nucleotide exchange factor 12 enables IEA InterPro GO_REF:0000002 NCBI chr 1:111,744,526...111,893,886
Ensembl chr 1:111,744,597...111,894,251 		JBrowse link
G ARRB1 arrestin beta 1 enables ISO (PMID:15611106) UniProt PMID:15611106 NCBI chr 1:66,489,358...66,580,167
Ensembl chr 1:66,490,102...66,580,154 		JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 8:124,515,274...124,912,076
Ensembl chr 8:124,514,210...124,869,668 		JBrowse link
G ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr14:98,244,584...98,451,017
Ensembl chr14:98,246,944...98,450,719 		JBrowse link
G ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:109,193,261...109,248,104
Ensembl chr20:109,193,469...109,248,242 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase enables IEA InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr19:2,569,841...2,703,703
Ensembl chr19:2,566,190...2,702,920 		JBrowse link
G CDC42EP2 CDC42 effector protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:8,914,214...8,921,031
Ensembl chr 1:8,914,787...8,915,437 		JBrowse link
G CHM CHM Rab escort protein enables IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr  X:74,626,531...74,810,560
Ensembl chr  X:74,626,028...74,810,557 		JBrowse link
G CHN1 chimerin 1 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr10:60,334,829...60,540,309
Ensembl chr10:60,331,214...60,488,785 		JBrowse link
G CHN2 chimerin 2 enables IEA UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr21:28,855,658...29,170,500
Ensembl chr21:28,857,266...28,976,242 		JBrowse link
G DAB2IP DAB2 interacting protein enables ISO
IEA		 RGD
UniProt		 PMID:11812785 GO_REF:0000043 RGD:632628 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890 		JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr19:14,634,836...14,798,050
Ensembl chr19:14,635,947...14,787,591 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein NOT|enables ISO (PMID:17932950)
(PMID:17888903)		 UniProt
RGD		 PMID:7835339 PMID:17888903 PMID:17932950 RGD:68218 NCBI chr 8:11,211,230...11,632,278 JBrowse link
G DOCK2 dedicator of cytokinesis 2 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056 		JBrowse link
G DOCK3 dedicator of cytokinesis 3 enables IEA InterPro GO_REF:0000002 NCBI chr22:12,078,424...12,725,245
Ensembl chr22:12,078,627...12,726,074 		JBrowse link
G DOCK4 dedicator of cytokinesis 4 enables IEA InterPro GO_REF:0000002 NCBI chr21:80,548,079...81,022,410
Ensembl chr21:80,547,655...80,812,702 		JBrowse link
G DOCK5 dedicator of cytokinesis 5 enables IEA InterPro GO_REF:0000002 NCBI chr 8:23,310,524...23,540,174
Ensembl chr 8:23,310,673...23,540,478 		JBrowse link
G ECT2 epithelial cell transforming 2 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr15:16,612,738...16,685,455
Ensembl chr15:16,612,443...16,685,386 		JBrowse link
G ELMOD1 ELMO domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:99,017,566...99,095,362
Ensembl chr 1:99,046,421...99,094,803 		JBrowse link
G ELMOD2 ELMO domain containing 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 7:87,456,626...87,486,523
Ensembl chr 7:87,456,645...87,486,515 		JBrowse link
G ELMOD3 ELMO domain containing 3 NOT|enables ISO (PMID:17452337) UniProt PMID:17452337 NCBI chr14:21,765,160...21,803,774 JBrowse link
G EVI5 ecotropic viral integration site 5 enables ISO (PMID:17562788) UniProt PMID:17562788 NCBI chr20:40,469,415...40,751,561
Ensembl chr20:40,470,911...40,746,422 		JBrowse link
G EVI5L ecotropic viral integration site 5 like enables IEA Ensembl GO_REF:0000107 NCBI chr 6:7,286,836...7,320,475
Ensembl chr 6:7,302,122...7,321,464 		JBrowse link
G FLCN folliculin enables IEA Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr16:16,245,840...16,271,465
Ensembl chr16:16,245,715...16,267,698 		JBrowse link
G GARNL3 GTPase activating Rap/RanGAP domain like 3 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 NCBI chr12:10,734,969...10,911,786
Ensembl chr12:10,734,798...10,911,816 		JBrowse link
G GDI1 GDP dissociation inhibitor 1 enables IEA UniProt GO_REF:0000043
G GDI2 GDP dissociation inhibitor 2 enables
contributes_to		 IEA
ISO		 (PMID:7782346) UniProt
MGI		 PMID:7782346 GO_REF:0000043 NCBI chr 9:5,876,245...5,923,011
Ensembl chr 9:5,877,042...5,922,968 		JBrowse link
G GIT1 GIT ArfGAP 1 enables ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:9826657 PMID:16439353 GO_REF:0000002 GO_REF:0000118 RGD:11344921 RGD:68782 NCBI chr16:23,313,629...23,329,665
Ensembl chr16:23,315,439...23,329,469 		JBrowse link
G GIT2 GIT ArfGAP 2 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr11:105,171,441...105,235,661
Ensembl chr11:105,169,099...105,235,290 		JBrowse link
G GMIP GEM interacting protein enables ISO (PMID:12093360) HGNC-UCL PMID:12093360 NCBI chr 6:18,088,545...18,102,718
Ensembl chr 6:18,088,098...18,101,118 		JBrowse link
G GNAQ G protein subunit alpha q enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
G GNB5 G protein subunit beta 5 contributes_to
enables		 ISO
IEA		 (PMID:27677260) UniProtKB
Ensembl		 PMID:27677260 GO_REF:0000107 NCBI chr26:31,209,843...31,265,440
Ensembl chr26:31,209,896...31,266,873 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B enables ISO (MGI:86840|PMID:8621713) UniProt PMID:8621713 MGI:86840 NCBI chr10:117,132,919...117,152,132
Ensembl chr10:117,133,195...117,149,681 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr29:9,363,273...9,485,644
Ensembl chr29:9,362,926...9,485,526 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit enables ISO (PMID:11804590) UniProt PMID:11804590 NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546 		JBrowse link
G LARS1 leucyl-tRNA synthetase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr23:48,691,361...48,761,664
Ensembl chr23:48,677,622...48,761,596 		JBrowse link
G LLGL1 LLGL scribble cell polarity complex component 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:17,266,648...17,285,460
Ensembl chr16:17,266,684...17,284,076 		JBrowse link
G LLGL2 LLGL scribble cell polarity complex component 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:46,103,080...46,151,576
Ensembl chr16:46,102,939...46,135,594 		JBrowse link
G LOC103217211 prolactin regulatory element-binding protein-like enables IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118 NCBI chr10:50,173,637...50,175,528 JBrowse link
G LOC103223283 pyridoxal phosphate phosphatase enables IEA InterPro GO_REF:0000002 NCBI chr19:20,340,535...20,357,426
Ensembl chr19:20,360,108...20,368,247
Ensembl chr19:20,360,108...20,368,247 		JBrowse link
G LOC103231590 rho GTPase-activating protein 6 enables IEA Ensembl GO_REF:0000107 NCBI chr  X:9,595,772...10,165,129
Ensembl chr  X:9,597,101...9,656,573 		JBrowse link
G LOC103232807 rho GTPase-activating protein 4 ISO RGD PMID:12414125 RGD:632235 NCBI chr  X:128,331,693...128,351,169
Ensembl chr  X:128,330,060...128,350,324 		JBrowse link
G LOC103245928 rho GTPase-activating protein 11B enables ISO (PMID:27957544) UniProt PMID:27957544 NCBI chr26:50,246,538...50,269,273
Ensembl chr26:50,245,229...50,269,418 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 enables ISO (PMID:17442267) UniProt PMID:17442267 NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216 		JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:53,802,594...53,827,763
Ensembl chr 5:53,805,020...53,827,648 		JBrowse link
G MYO9A myosin IXA enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr26:11,339,033...11,640,982
Ensembl chr26:11,339,246...11,639,956 		JBrowse link
G MYO9B myosin IXB enables ISO
IEA		 RGD
InterPro
Ensembl
UniProt		 PMID:7882973 PMID:9348541 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 RGD:1581711 RGD:633447 NCBI chr 6:15,571,276...15,707,571
Ensembl chr 6:15,596,583...15,707,567 		JBrowse link
G NCKAP1L NCK associated protein 1 like enables ISO (PMID:16417406) UniProt PMID:16417406 NCBI chr11:50,611,193...50,658,800 JBrowse link
G NCKAP1L NCK associated protein 1 like enables IEA Ensembl GO_REF:0000107 Ensembl chr11:50,611,181...50,647,519 JBrowse link
G NF1 neurofibromin 1 enables IEA UniProt GO_REF:0000043 NCBI chr16:24,550,983...24,836,311
Ensembl chr16:24,550,977...24,836,307 		JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit enables ISO (PMID:30651352), (PMID:35338845) UniProt PMID:30651352 PMID:35338845 NCBI chr22:11,735,853...11,739,325 JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr22:11,736,772...11,739,128 JBrowse link
G NPRL3 NPR3 like, GATOR1 complex subunit enables IEA Ensembl GO_REF:0000107 NCBI chr 5:40,674...94,265
Ensembl chr 5:43,150...94,174 		JBrowse link
G NRP1 neuropilin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:32,474,787...32,632,746
Ensembl chr 9:32,474,309...32,633,101 		JBrowse link
G OCRL OCRL inositol polyphosphate-5-phosphatase enables IEA Ensembl GO_REF:0000107 NCBI chr  X:104,784,900...104,834,718
Ensembl chr  X:104,785,526...104,837,243 		JBrowse link
G OPHN1 oligophrenin 1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:57,906,868...58,291,358
Ensembl chr  X:57,911,555...58,290,900 		JBrowse link
G PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase enables IEA Ensembl GO_REF:0000107 NCBI chr11:128,053,176...128,064,030
Ensembl chr11:128,053,795...128,065,720 		JBrowse link
G PLCB1 phospholipase C beta 1 enables ISO (PMID:1322796) BHF-UCL PMID:1322796 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLEKHG6 pleckstrin homology and RhoGEF domain containing G6 enables IEA InterPro GO_REF:0000002 NCBI chr11:6,346,009...6,364,280
Ensembl chr11:6,348,244...6,364,207 		JBrowse link
G PREB prolactin regulatory element binding enables IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118 NCBI chr14:80,485,178...80,489,081
Ensembl chr14:80,485,252...80,488,438 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:63,781,892...64,061,222
Ensembl chr 8:63,781,948...64,060,864 		JBrowse link
G RAB3GAP1 RAB3 GTPase activating protein catalytic subunit 1 enables IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr10:19,295,294...19,401,595
Ensembl chr10:19,295,351...19,402,212 		JBrowse link
G RAB3GAP2 RAB3 GTPase activating non-catalytic protein subunit 2 enables IEA UniProt GO_REF:0000043 NCBI chr25:9,293,791...9,411,950
Ensembl chr25:9,293,838...9,415,319 		JBrowse link
G RABEP1 rabaptin, RAB GTPase binding effector protein 1 enables IEA InterPro GO_REF:0000002 NCBI chr16:4,670,448...4,795,309
Ensembl chr16:4,670,499...4,792,689 		JBrowse link
G RABEP2 rabaptin, RAB GTPase binding effector protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr 5:26,130,667...26,165,415
Ensembl chr 5:26,131,512...26,168,514 		JBrowse link
G RABGAP1 RAB GTPase activating protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr12:15,028,205...15,198,953
Ensembl chr12:15,028,203...15,177,626 		JBrowse link
G RABGAP1L RAB GTPase activating protein 1 like enables ISO (PMID:16923123) MGI PMID:16923123 NCBI chr25:54,265,906...55,034,061 JBrowse link
G RACGAP1 Rac GTPase activating protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr11:46,218,987...46,260,477
Ensembl chr11:46,220,090...46,254,602 		JBrowse link
G RALBP1 ralA binding protein 1 enables IEA Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr18:68,353,823...68,415,221
Ensembl chr18:68,391,245...68,413,555 		JBrowse link
G RALGAPA1 Ral GTPase activating protein catalytic subunit alpha 1 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr24:12,344,951...12,615,669
Ensembl chr24:12,344,934...12,615,622 		JBrowse link
G RALGAPA2 Ral GTPase activating protein catalytic subunit alpha 2 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr 2:49,381,251...49,704,946
Ensembl chr 2:49,465,647...49,645,287 		JBrowse link
G RALGAPB Ral GTPase activating protein non-catalytic subunit beta enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 NCBI chr 2:25,177,380...25,285,938
Ensembl chr 2:25,176,956...25,307,991 		JBrowse link
G RANBP1 RAN binding protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr19:5,611,968...5,622,414
Ensembl chr19:5,612,268...5,622,191 		JBrowse link
G RANBP2 RAN binding protein 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr14:12,250,986...12,318,801
Ensembl chr14:12,251,007...12,319,735 		JBrowse link
G RANBP3L RAN binding protein 3 like enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:35,095,520...35,156,378
Ensembl chr 4:35,096,196...35,155,543 		JBrowse link
G RANGAP1 Ran GTPase activating protein 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr19:23,789,839...23,829,653
Ensembl chr19:23,788,241...23,829,631 		JBrowse link
G RAP1GAP RAP1 GTPase activating protein enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr20:110,967,457...111,040,940
Ensembl chr20:110,987,308...111,040,947 		JBrowse link
G RAP1GAP2 RAP1 GTPase activating protein 2 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr16:2,397,634...2,643,078
Ensembl chr16:2,385,707...2,643,074 		JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 enables ISO (PMID:10934204) UniProt PMID:10934204 NCBI chr 7:105,672,583...105,883,544
Ensembl chr 7:105,624,608...105,884,366 		JBrowse link
G RASA1 RAS p21 protein activator 1 enables ISO
IEA		 RGD
UniProt		 PMID:8226805 GO_REF:0000043 RGD:9999452 NCBI chr 4:81,249,851...81,371,486
Ensembl chr 4:81,249,805...81,370,453 		JBrowse link
G RASA2 RAS p21 protein activator 2 enables ISO
IEA		 RGD
UniProt
InterPro		 PMID:7935405 GO_REF:0000002 GO_REF:0000043 RGD:729718 NCBI chr15:48,995,847...49,118,895
Ensembl chr15:48,995,848...49,118,824 		JBrowse link
G RASA3 RAS p21 protein activator 3 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 3:91,848,158...91,974,675
Ensembl chr 3:91,848,160...91,974,555 		JBrowse link
G RASAL1 RAS protein activator like 1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:108,344,753...108,385,009
Ensembl chr11:108,342,809...108,384,530 		JBrowse link
G RASAL2 RAS protein activator like 2 enables IEA UniProt GO_REF:0000043 NCBI chr25:50,838,985...51,211,683
Ensembl chr25:50,840,184...50,941,942 		JBrowse link
G RASAL3 RAS protein activator like 3 enables IEA UniProt GO_REF:0000043 NCBI chr 6:14,054,517...14,068,423
Ensembl chr 6:14,054,522...14,064,590 		JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 enables IEA Ensembl GO_REF:0000107 NCBI chr14:73,871,343...73,950,119
Ensembl chr14:73,895,534...73,946,358 		JBrowse link
G RGS1 regulator of G protein signaling 1 enables IEA Ensembl GO_REF:0000107 NCBI chr25:36,853,413...36,868,599
Ensembl chr25:36,853,340...36,857,663 		JBrowse link
G RGS10 regulator of G protein signaling 10 enables IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:112,288,352...112,330,455
Ensembl chr 9:112,288,596...112,315,220 		JBrowse link
G RGS12 regulator of G protein signaling 12 ISO RGD PMID:9651375 RGD:69959 NCBI chr27:45,302,193...45,444,012 JBrowse link
G RGS12 regulator of G protein signaling 12 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 Ensembl chr27:45,292,943...45,421,971 JBrowse link
G RGS14 regulator of G protein signaling 14 enables IEA Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr23:79,370,320...79,385,355
Ensembl chr23:79,370,087...79,387,192 		JBrowse link
G RGS16 regulator of G protein signaling 16 enables IEA Ensembl GO_REF:0000107 NCBI chr25:46,764,097...46,769,895
Ensembl chr25:46,764,134...46,769,896 		JBrowse link
G RGS18 regulator of G protein signaling 18 enables IEA Ensembl GO_REF:0000107 NCBI chr25:37,241,785...37,269,603
Ensembl chr25:37,240,813...37,269,655 		JBrowse link
G RGS2 regulator of G protein signaling 2 enables IEA UniProt GO_REF:0000043 NCBI chr25:36,620,047...36,623,367
Ensembl chr25:36,619,140...36,623,308 		JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:9430692 PMID:10942773 PMID:20530129 RGD:13524554 RGD:7207369 RGD:7207375 NCBI chr25:65,729,344...65,735,278
Ensembl chr25:65,726,394...65,735,381 		JBrowse link
G RGS6 regulator of G protein signaling 6 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr24:49,161,466...49,803,209
Ensembl chr24:49,591,815...49,775,653 		JBrowse link
G RGS7 regulator of G protein signaling 7 enables IEA Ensembl GO_REF:0000107 NCBI chr25:77,876,831...78,444,732
Ensembl chr25:77,876,833...78,191,928 		JBrowse link
G RGS8 regulator of G protein signaling 8 enables IEA Ensembl GO_REF:0000107 NCBI chr25:46,683,978...46,724,205
Ensembl chr25:46,683,783...46,726,543 		JBrowse link
G RGS9 regulator of G protein signaling 9 enables ISO
IEA		 RGD
TreeGrafter		 PMID:9765512 GO_REF:0000118 RGD:69964 NCBI chr16:56,199,051...56,291,002
Ensembl chr16:56,199,343...56,288,290 		JBrowse link
G RIC8A RIC8 guanine nucleotide exchange factor A enables ISO PMID:12509430
PMID:21158412		 MGI
UniProt		 PMID:12509430 PMID:21158412 RGD:633903 RGD:8553612 NCBI chr 1:18,597...25,398
Ensembl chr 1:19,013...25,473 		JBrowse link
G RIN1 Ras and Rab interactor 1 enables IEA UniProt GO_REF:0000043 NCBI chr 1:7,940,856...7,945,419
Ensembl chr 1:7,941,082...7,945,206 		JBrowse link
G RIN2 Ras and Rab interactor 2 enables IEA UniProt GO_REF:0000043 NCBI chr 2:48,768,647...49,020,208
Ensembl chr 2:48,905,779...49,021,368 		JBrowse link
G RIN3 Ras and Rab interactor 3 enables IEA UniProt GO_REF:0000043 NCBI chr24:70,261,693...70,447,126
Ensembl chr24:70,303,459...70,450,059 		JBrowse link
G RINL Ras and Rab interactor like enables IEA UniProt GO_REF:0000043 NCBI chr 6:33,479,424...33,493,021
Ensembl chr 6:33,479,561...33,491,293 		JBrowse link
G RP2 RP2 activator of ARL3 GTPase enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr  X:44,048,319...44,090,011
Ensembl chr  X:44,048,317...44,089,988 		JBrowse link
G SEC23A SEC23 homolog A, COPII coat complex component enables IEA TreeGrafter GO_REF:0000118 NCBI chr24:15,801,945...15,874,938
Ensembl chr24:15,801,509...15,874,994 		JBrowse link
G SGSM1 small G protein signaling modulator 1 enables IEA InterPro GO_REF:0000002 NCBI chr19:7,906,444...8,024,484
Ensembl chr19:7,906,657...8,024,488 		JBrowse link
G SGSM2 small G protein signaling modulator 2 enables IEA InterPro GO_REF:0000002 NCBI chr16:1,970,412...2,012,417
Ensembl chr16:1,970,456...2,014,384 		JBrowse link
G SGSM3 small G protein signaling modulator 3 enables IEA Ensembl GO_REF:0000107 NCBI chr19:22,943,787...22,979,899
Ensembl chr19:22,970,595...22,982,856 		JBrowse link
G SIPA1 signal-induced proliferation-associated 1 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr 1:8,588,221...8,601,310
Ensembl chr 1:8,586,685...8,598,455 		JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr24:48,542,976...48,965,378
Ensembl chr24:48,636,323...48,965,371 		JBrowse link
G SIPA1L2 signal induced proliferation associated 1 like 2 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr25:69,616,236...69,732,476
Ensembl chr25:69,615,794...69,732,519 		JBrowse link
G SIPA1L3 signal induced proliferation associated 1 like 3 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr 6:32,548,602...32,852,769
Ensembl chr 6:32,671,179...32,837,875 		JBrowse link
G SMAP1 small ArfGAP 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr17:4,149,801...4,333,713
Ensembl chr17:4,148,285...4,333,642 		JBrowse link
G SMAP2 small ArfGAP2 enables IEA InterPro GO_REF:0000002 NCBI chr20:92,496,890...92,545,767
Ensembl chr20:92,498,113...92,545,803 		JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit enables IEA InterPro GO_REF:0000002 NCBI chr16:17,358,952...17,367,323
Ensembl chr16:17,359,577...17,366,851 		JBrowse link
G SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 enables IEA InterPro GO_REF:0000002 NCBI chr11:59,548,703...59,856,493
Ensembl chr11:59,549,225...59,851,302 		JBrowse link
G SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 enables ISO (MGI:4366584|PMID:19737524), (MGI:6867123|PMID:26439400)
(PMID:21148482), (PMID:27373832)
(PMID:20810653)		 UniProt PMID:19737524 PMID:20810653 PMID:21148482 PMID:26439400 PMID:27373832 MGI:4366584 MGI:6867123 NCBI chr25:22,897,699...23,147,097
Ensembl chr25:22,897,469...23,145,218 		JBrowse link
G STARD13 StAR related lipid transfer domain containing 13 enables IEA UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000118 NCBI chr 3:11,837,218...12,388,706
Ensembl chr 3:11,836,977...11,974,362 		JBrowse link
G STXBP5 syntaxin binding protein 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr13:24,365,022...24,559,249
Ensembl chr13:24,367,627...24,559,269 		JBrowse link
G STXBP5L syntaxin binding protein 5L enables IEA TreeGrafter GO_REF:0000118 NCBI chr22:59,460,278...59,938,228
Ensembl chr22:59,465,870...59,938,129 		JBrowse link
G SYDE1 synapse defective Rho GTPase homolog 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:13,709,110...13,717,249
Ensembl chr 6:13,709,148...13,716,241 		JBrowse link
G SYNGAP1 synaptic Ras GTPase activating protein 1 enables ISO
IEA		 RGD
UniProt
Ensembl		 PMID:14970204 PMID:16427633 PMID:21382555 GO_REF:0000043 GO_REF:0000107 RGD:7241543 RGD:7241546 RGD:7241548 NCBI chr17:38,612,777...38,646,382
Ensembl chr17:38,617,679...38,646,192 		JBrowse link
G TAGAP T cell activation RhoGTPase activating protein enables IEA InterPro GO_REF:0000002 NCBI chr13:86,620,021...86,630,814
Ensembl chr13:86,620,046...86,630,956 		JBrowse link
G TBC1D10B TBC1 domain family member 10B enables IEA Ensembl GO_REF:0000107 NCBI chr 5:27,033,341...27,047,635
Ensembl chr 5:27,031,651...27,047,486 		JBrowse link
G TBC1D13 TBC1 domain family member 13 enables IEA TreeGrafter GO_REF:0000118 NCBI chr12:9,333,341...9,362,817
Ensembl chr12:9,333,685...9,362,675 		JBrowse link
G TBC1D15 TBC1 domain family member 15 enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:67,472,771...67,554,329
Ensembl chr11:67,473,030...67,556,694 		JBrowse link
G TBC1D16 TBC1 domain family member 16 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:71,906,309...72,003,457
Ensembl chr16:71,906,890...71,981,424 		JBrowse link
G TBC1D17 TBC1 domain family member 17 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:43,034,986...43,045,462
Ensembl chr 6:43,035,280...43,045,646 		JBrowse link
G TBC1D2 TBC1 domain family member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr12:41,160,921...41,221,547
Ensembl chr12:41,161,695...41,222,815 		JBrowse link
G TBC1D20 TBC1 domain family member 20 enables IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:56,065,975...56,093,521
Ensembl chr 2:56,066,042...56,094,333 		JBrowse link
G TBC1D21 TBC1 domain family member 21 enables IEA TreeGrafter GO_REF:0000118 NCBI chr26:9,599,042...9,616,305
Ensembl chr26:9,599,157...9,613,986 		JBrowse link
G TBC1D22B TBC1 domain family member 22B enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:34,807,334...34,880,611
Ensembl chr17:34,809,104...34,880,599 		JBrowse link
G TBC1D25 TBC1 domain family member 25 enables ISO (PMID:21383079) UniProt PMID:21383079 NCBI chr  X:45,671,217...45,691,307 JBrowse link
G TBC1D25 TBC1 domain family member 25 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr  X:45,671,248...45,691,889 JBrowse link
G TBC1D30 TBC1 domain family member 30 enables IEA Ensembl GO_REF:0000107 NCBI chr11:60,456,397...60,564,293
Ensembl chr11:60,516,158...60,564,477 		JBrowse link
G TBC1D5 TBC1 domain family member 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr15:62,009,952...62,569,187
Ensembl chr15:62,006,701...62,358,449 		JBrowse link
G TBC1D7 TBC1 domain family member 7 enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr17:58,822,288...58,844,659
Ensembl chr17:58,822,415...58,846,047 		JBrowse link
G TBC1D8 TBC1 domain family member 8 enables IEA UniProt GO_REF:0000043 NCBI chr14:4,715,787...4,846,284
Ensembl chr14:4,716,368...4,846,357 		JBrowse link
G TBC1D8B TBC1 domain family member 8B enables IEA UniProt GO_REF:0000043 NCBI chr  X:94,639,288...94,706,276
Ensembl chr  X:94,639,363...94,706,308 		JBrowse link
G TBC1D9 TBC1 domain family member 9 enables IEA UniProt GO_REF:0000043 NCBI chr 7:87,553,136...87,691,254
Ensembl chr 7:87,552,715...87,690,438 		JBrowse link
G TBC1D9B TBC1 domain family member 9B enables IEA UniProt GO_REF:0000043 NCBI chr23:81,595,246...81,635,828
Ensembl chr23:81,594,392...81,635,808 		JBrowse link
G TBCD tubulin folding cofactor D enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr16:74,646,620...74,828,874
Ensembl chr16:74,646,464...74,828,163 		JBrowse link
G THY1 Thy-1 cell surface antigen enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:110,787,213...110,791,536
Ensembl chr 1:110,783,877...110,791,569 		JBrowse link
G TIAM2 TIAM Rac1 associated GEF 2 enables ISO (PMID:11707441) MGI PMID:11707441 NCBI chr13:82,537,021...82,823,525
Ensembl chr13:82,688,773...82,822,949 		JBrowse link
G TSC2 TSC complex subunit 2 enables ISO
IEA		 RGD
TreeGrafter
InterPro
Ensembl
UniProt		 PMID:12869586 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:1580520 NCBI chr 5:1,946,534...1,985,168
Ensembl chr 5:1,946,927...1,987,682 		JBrowse link
G USP6NL USP6 N-terminal like enables ISO (PMID:17562788), (PMID:17684057) UniProt PMID:17562788 PMID:17684057 NCBI chr 9:11,516,243...11,670,302
Ensembl chr 9:11,514,090...11,670,301 		JBrowse link
G WNT11 Wnt family member 11 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:67,393,975...67,427,247
Ensembl chr 1:67,399,074...67,418,509 		JBrowse link
guanylate cyclase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCA2A guanylate cyclase activator 2A ISO RGD PMID:1346555 RGD:731149 NCBI chr20:90,757,887...90,760,598 JBrowse link
G GUCA2A guanylate cyclase activator 2A enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr20:90,758,455...90,760,641 JBrowse link
G GUCA2B guanylate cyclase activator 2B enables IEA InterPro GO_REF:0000002 NCBI chr20:90,767,183...90,770,403
Ensembl chr20:90,767,609...90,770,198 		JBrowse link
kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR2B activin A receptor type 2B enables ISO (PMID:16806156) MGI PMID:16806156 NCBI chr15:923,222...962,438 JBrowse link
G ACVR2B activin A receptor type 2B enables IEA Ensembl GO_REF:0000107 Ensembl chr15:933,070...939,419 JBrowse link
G BCL10 BCL10 immune signaling adaptor contributes_to
enables		 ISO
IEA		 (PMID:15125833) UniProtKB
TreeGrafter
Ensembl		 PMID:15125833 GO_REF:0000107 GO_REF:0000118 NCBI chr20:48,073,489...48,084,635
Ensembl chr20:48,073,800...48,085,136 		JBrowse link
G ITSN1 intersectin 1 enables ISO (PMID:17875942) MGI PMID:17875942 NCBI chr 2:58,298,529...58,543,297
Ensembl chr 2:58,301,399...58,543,281 		JBrowse link
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 enables ISO (PMID:15263099) MGI PMID:15263099 NCBI chr 7:48,009,857...48,025,783 JBrowse link
G MALT1 MALT1 paracaspase contributes_to ISO (PMID:15125833) UniProtKB PMID:15125833 NCBI chr18:20,984,985...21,064,198
Ensembl chr18:20,985,819...21,054,554 		JBrowse link
G MOB1B MOB kinase activator 1B enables IEA Ensembl GO_REF:0000107 NCBI chr 7:19,418,464...19,493,969
Ensembl chr 7:19,418,548...19,491,465 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 enables ISO (PMID:12464436) MGI PMID:12464436 NCBI chr19:21,971,362...22,004,289 JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 enables IEA Ensembl GO_REF:0000107 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
L-dopa decarboxylase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase enables IEA Ensembl GO_REF:0000107 NCBI chr20:123,776,084...123,808,031
Ensembl chr20:123,776,297...123,798,434 		JBrowse link
lipase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase enables IEA Ensembl GO_REF:0000107 NCBI chr22:5,109,699...5,139,021
Ensembl chr22:5,109,765...5,137,673 		JBrowse link
G APOA5 apolipoprotein A5 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:108,154,880...108,158,998
Ensembl chr 1:108,155,641...108,157,375 		JBrowse link
lipoprotein lipase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:108,154,880...108,158,998
Ensembl chr 1:108,155,641...108,157,375 		JBrowse link
G APOC2 apolipoprotein C2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:38,406,829...38,411,239
Ensembl chr 6:38,409,641...38,410,927 		JBrowse link
G APOH apolipoprotein H enables ISO (PMID:7417307) BHF-UCL PMID:7417307 NCBI chr16:55,209,142...55,231,176 JBrowse link
G APOH apolipoprotein H enables IEA Ensembl GO_REF:0000107 Ensembl chr16:55,209,156...55,231,076 JBrowse link
G GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:137,433,669...137,440,681
Ensembl chr 8:137,436,997...137,440,909 		JBrowse link
ornithine decarboxylase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZIN1 antizyme inhibitor 1 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 8:97,679,775...97,717,486
Ensembl chr 8:97,679,468...97,696,928 		JBrowse link
G AZIN2 antizyme inhibitor 2 enables ISO (PMID:17900240)
(PMID:16916800)
(MGI:5574513|PMID:24967154)		 UniProt
MGI		 PMID:16916800 PMID:17900240 PMID:24967154 MGI:5574513 NCBI chr20:99,757,861...99,804,671 JBrowse link
G AZIN2 antizyme inhibitor 2 enables IEA Ensembl GO_REF:0000107 Ensembl chr20:99,757,861...99,804,601 JBrowse link
peptidase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein ISO RGD PMID:12493564 RGD:634664 NCBI chr 2:66,037,224...66,320,860
Ensembl chr 2:66,037,261...66,321,306 		JBrowse link
G CAV1 caveolin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator enables ISO (PMID:21368763) MGI PMID:21368763 NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652 		JBrowse link
G CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X enables IEA Ensembl GO_REF:0000107 NCBI chr26:18,401,593...18,441,286
Ensembl chr26:18,401,798...18,440,915 		JBrowse link
G FBLN1 fibulin 1 enables IEA InterPro GO_REF:0000002 NCBI chr19:27,962,669...28,061,356
Ensembl chr19:27,962,642...28,061,364 		JBrowse link
G FGL2 fibrinogen like 2 enables ISO (PMID:15100314) AgBase PMID:15100314 NCBI chr21:71,735,486...71,741,951
Ensembl chr21:71,735,253...71,742,954 		JBrowse link
G FN1 fibronectin 1 enables ISO (PMID:16061471) MGI PMID:16061471 NCBI chr10:101,177,867...101,254,613
Ensembl chr10:101,176,789...101,254,633 		JBrowse link
G PCOLCE procollagen C-endopeptidase enhancer enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:12,604,552...12,610,814
Ensembl chr28:12,604,526...12,610,814 		JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 enables ISO (PMID:12393877) MGI PMID:12393877 NCBI chr15:47,743,530...47,815,448
Ensembl chr15:47,743,589...47,817,429 		JBrowse link
G PSME4 proteasome activator subunit 4 enables IEA InterPro GO_REF:0000002 NCBI chr14:52,999,960...53,108,624
Ensembl chr14:52,999,960...53,108,885 		JBrowse link
G SVBP small vasohibin binding protein enables IEA Ensembl GO_REF:0000107 NCBI chr20:90,115,509...90,128,169
Ensembl chr20:90,116,353...90,127,807 		JBrowse link
peptidase activator activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSC cathepsin C enables ISO (PMID:20435891) MGI PMID:20435891 NCBI chr 1:79,426,556...79,468,464
Ensembl chr 1:79,426,549...79,468,340 		JBrowse link
G CTSH cathepsin H enables ISO (PMID:20435891) MGI PMID:20435891 NCBI chr26:4,451,731...4,473,220
Ensembl chr26:4,451,774...4,472,855 		JBrowse link
phosphatase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G GTF2F1 general transcription factor IIF subunit 1 enables ISO (PMID:12721286) UniProt PMID:12721286 NCBI chr 6:5,996,585...6,006,893 JBrowse link
G PTPA protein phosphatase 2 phosphatase activator enables IEA InterPro GO_REF:0000002 NCBI chr12:9,017,533...9,056,856
Ensembl chr12:9,019,024...9,056,703 		JBrowse link
phosphatidylcholine-sterol O-acyltransferase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:108,201,967...108,203,902
Ensembl chr 1:108,201,439...108,203,609 		JBrowse link
G APOA2 apolipoprotein A2 enables ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr20:2,757,939...2,760,356
Ensembl chr20:2,759,237...2,760,686 		JBrowse link
G APOA4 apolipoprotein A4 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:108,186,627...108,190,508
Ensembl chr 1:108,186,921...108,189,698 		JBrowse link
G APOE apolipoprotein E enables IEA Ensembl GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
phospholipase A2 activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 ISO RGD PMID:12492473 RGD:629558 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
phospholipase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC2 apolipoprotein C2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:38,406,829...38,411,239
Ensembl chr 6:38,409,641...38,410,927 		JBrowse link
G ARHGAP6 Rho GTPase activating protein 6 enables ISO (PMID:18434237) BHF-UCL PMID:18434237
G BTK Bruton tyrosine kinase enables ISO (PMID:11606584) ARUK-UCL PMID:11606584 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G BTK Bruton tyrosine kinase enables IEA Ensembl GO_REF:0000107 Ensembl chr  X:89,690,671...89,711,218 JBrowse link
G CCL5 C-C motif chemokine ligand 5 enables IEA Ensembl GO_REF:0000107 NCBI chr16:29,351,214...29,361,317 JBrowse link
G CCL8 C-C motif chemokine ligand 8 enables ISO (PMID:10734056) UniProt PMID:10734056 NCBI chr16:27,821,149...27,823,919
Ensembl chr16:27,821,970...27,823,528 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase enables IEA Ensembl GO_REF:0000107 NCBI chr13:61,988,265...62,218,756
Ensembl chr13:62,159,874...62,219,672 		JBrowse link
G GM2A GM2 ganglioside activator ISO RGD PMID:9770472 RGD:1598995 NCBI chr23:53,808,447...53,831,489 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase enables ISO (PMID:11606584) ARUK-UCL PMID:11606584 NCBI chr20:100,582,718...100,618,041 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase enables IEA Ensembl GO_REF:0000107 Ensembl chr20:100,583,452...100,618,015 JBrowse link
G LOC103231590 rho GTPase-activating protein 6 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:9,595,772...10,165,129
Ensembl chr  X:9,597,101...9,656,573 		JBrowse link
G LOC103242767 C-C motif chemokine 3 enables ISO (PMID:10734056) UniProt PMID:10734056 NCBI chr16:29,887,799...29,897,664
Ensembl chr16:29,887,883...29,897,544 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 enables IEA Ensembl GO_REF:0000107
G SRC SRC proto-oncogene, non-receptor tyrosine kinase enables IEA Ensembl GO_REF:0000107 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
phospholipase C activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLC1 DLC1 Rho GTPase activating protein ISO RGD PMID:7835339 RGD:68218 NCBI chr 8:11,211,230...11,632,278 JBrowse link
G HRAS HRas proto-oncogene, GTPase enables ISO (PMID:11022048) UniProt PMID:11022048 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
phospholipase D activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:7972129 RGD:9685186 NCBI chr25:1,628,836...1,644,502
Ensembl chr25:1,628,751...1,644,499 		JBrowse link
G ARF4 ADP ribosylation factor 4 enables ISO (PMID:12446727) UniProt PMID:12446727 NCBI chr22:18,879,064...18,904,234
Ensembl chr22:18,877,715...18,903,891 		JBrowse link
G ARL1 ADP ribosylation factor like GTPase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr11:96,662,260...96,674,662
Ensembl chr11:96,659,769...96,675,486 		JBrowse link
protein kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 enables ISO (PMID:14761976) RGD
MGI		 PMID:11136977 PMID:14761976 RGD:632423 NCBI chr11:53,638,722...53,655,826
Ensembl chr11:53,640,079...53,651,913 		JBrowse link
G AJUBA ajuba LIM protein enables IEA Ensembl GO_REF:0000107 NCBI chr29:23,341,841...23,352,630
Ensembl chr29:23,341,249...23,352,685 		JBrowse link
G CAB39 calcium binding protein 39 enables ISO (PMID:19892943) UniProt PMID:19892943 NCBI chr10:116,749,173...116,860,814
Ensembl chr10:116,798,825...116,861,332 		JBrowse link
G CCNQ cyclin Q enables ISO (PMID:24218572) MGI PMID:24218572 NCBI chr  X:128,018,651...128,030,122
Ensembl chr  X:128,019,090...128,030,083 		JBrowse link
G DAXX death domain associated protein enables IEA Ensembl GO_REF:0000107 NCBI chr17:38,754,227...38,758,714
Ensembl chr17:38,754,280...38,759,071 		JBrowse link
G DUSP19 dual specificity phosphatase 19 enables ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr10:68,582,797...68,607,249
Ensembl chr10:68,583,314...68,610,537 		JBrowse link
G EPO erythropoietin enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:12,487,222...12,491,986
Ensembl chr28:12,489,766...12,491,908 		JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:12,800,517...12,820,861
Ensembl chr11:12,816,729...12,820,805 		JBrowse link
G GPRC5B G protein-coupled receptor class C group 5 member B enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:18,138,173...18,166,048
Ensembl chr 5:18,141,230...18,165,138 		JBrowse link
G HMGB1 high mobility group box 1 enables ISO (PMID:7741753) MGI PMID:7741753 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G LOC103234603 60S acidic ribosomal protein P1-like enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:32,159,000...32,159,451 JBrowse link
G LOC103243316 protein DBF4 homolog B enables IEA Ensembl GO_REF:0000107 NCBI chr16:61,652,845...61,693,154 JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 enables ISO (PMID:10644344) GO_Central PMID:10644344 NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 enables ISO (PMID:32610081) UniProt PMID:32610081 NCBI chr10:58,573,303...58,764,759 JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 enables ISO (PMID:12244047) MGI PMID:12244047 NCBI chr19:33,079,548...33,090,221
Ensembl chr19:33,079,626...33,091,514 		JBrowse link
G MOB1B MOB kinase activator 1B enables IEA TreeGrafter GO_REF:0000118 NCBI chr 7:19,418,464...19,493,969
Ensembl chr 7:19,418,548...19,491,465 		JBrowse link
G MOB2 MOB kinase activator 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:1,267,041...1,338,940
Ensembl chr 1:1,266,952...1,338,895 		JBrowse link
G MT3 metallothionein 3 enables ISO (PMID:18295594) UniProt PMID:18295594 NCBI chr 5:42,502,306...42,504,467 JBrowse link
G MT3 metallothionein 3 enables IEA Ensembl GO_REF:0000107 Ensembl chr 5:42,502,959...42,504,325 JBrowse link
G NCKAP1L NCK associated protein 1 like enables ISO (PMID:16417406) UniProt PMID:16417406 NCBI chr11:50,611,193...50,658,800 JBrowse link
G NCKAP1L NCK associated protein 1 like enables IEA Ensembl GO_REF:0000107 Ensembl chr11:50,611,181...50,647,519 JBrowse link
G NEK9 NIMA related kinase 9 enables ISO (PMID:12840024) UniProt PMID:12840024 NCBI chr24:52,297,211...52,342,359
Ensembl chr24:52,296,261...52,342,724 		JBrowse link
G PDE8A phosphodiesterase 8A enables IEA Ensembl GO_REF:0000107 NCBI chr29:3,214,183...3,367,051
Ensembl chr29:3,213,165...3,367,571 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha enables IEA Ensembl GO_REF:0000107 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 enables ISO (PMID:15877279) BHF-UCL PMID:15877279 NCBI chr21:119,738,976...120,058,831
Ensembl chr21:119,738,967...119,970,972 		JBrowse link
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 enables ISO (PMID:29170442) UniProt PMID:29170442 NCBI chr10:63,982,784...64,003,919 JBrowse link
G RGCC regulator of cell cycle enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:19,681,700...19,695,655
Ensembl chr 3:19,681,874...19,693,644 		JBrowse link
G RHEB Ras homolog, mTORC1 binding enables IEA Ensembl GO_REF:0000107 NCBI chr21:119,652,692...119,704,833
Ensembl chr21:119,652,127...119,703,458 		JBrowse link
G RPLP1 ribosomal protein lateral stalk subunit P1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr26:14,002,074...14,004,481
Ensembl chr26:14,002,075...14,004,474 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 enables IEA Ensembl GO_REF:0000107 NCBI chr16:72,513,593...72,916,950
Ensembl chr16:72,513,619...72,918,416 		JBrowse link
G SPDYA speedy/RINGO cell cycle regulator family member A enables ISO (PMID:28666995)
(PMID:28031483)		 UniProt
MGI		 PMID:28031483 PMID:28666995 NCBI chr14:78,756,606...78,792,788 JBrowse link
G STK11 serine/threonine kinase 11 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136 		JBrowse link
G STRADA STE20 related adaptor alpha enables ISO (PMID:19892943) UniProt PMID:19892943 NCBI chr16:57,550,698...57,587,995
Ensembl chr16:57,550,703...57,588,084 		JBrowse link
G TAOK1 TAO kinase 1 ISO RGD PMID:9786855 RGD:1299457 NCBI chr16:23,145,629...23,291,694 JBrowse link
G TOM1L1 target of myb1 like 1 membrane trafficking protein enables IEA Ensembl GO_REF:0000107 NCBI chr16:38,425,406...38,477,444
Ensembl chr16:38,414,535...38,477,416 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr11:736,668...893,404
Ensembl chr11:737,590...890,762 		JBrowse link
G WNT11 Wnt family member 11 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:67,393,975...67,427,247
Ensembl chr 1:67,399,074...67,418,509 		JBrowse link
protein phosphatase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GAT3 beta-1,3-glucuronyltransferase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:11,282,414...11,289,640
Ensembl chr 1:11,282,601...11,289,743 		JBrowse link
G CALM1 calmodulin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CALM2 calmodulin 2 enables IEA Ensembl GO_REF:0000107 NCBI chr14:60,027,884...60,042,041
Ensembl chr14:60,027,801...60,044,951
Ensembl chr 6:60,027,801...60,044,951
Ensembl chr24:60,027,801...60,044,951 		JBrowse link
G CALM3 calmodulin 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:39,957,012...39,966,562
Ensembl chr 6:39,957,320...39,966,581
Ensembl chr24:39,957,320...39,966,581
Ensembl chr14:39,957,320...39,966,581 		JBrowse link
G PHACTR4 phosphatase and actin regulator 4 enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr20:104,303,966...104,435,342
Ensembl chr20:104,302,429...104,367,831 		JBrowse link
G PPP2R5A protein phosphatase 2 regulatory subunit B'alpha enables IEA TreeGrafter GO_REF:0000118 NCBI chr25:17,163,429...17,237,519
Ensembl chr25:17,162,544...17,237,524 		JBrowse link
G PPP2R5B protein phosphatase 2 regulatory subunit B'beta enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:9,299,609...9,309,357
Ensembl chr 1:9,299,160...9,309,335 		JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma enables IEA TreeGrafter GO_REF:0000118 NCBI chr24:79,703,316...79,875,379
Ensembl chr24:79,703,312...79,875,389 		JBrowse link
G PPP2R5D protein phosphatase 2 regulatory subunit B'delta enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:29,147,560...29,175,700
Ensembl chr17:29,145,918...29,174,997 		JBrowse link
G PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon enables IEA TreeGrafter GO_REF:0000118 NCBI chr24:40,548,986...40,730,451
Ensembl chr24:40,553,635...40,633,392 		JBrowse link
G PPP4R3A protein phosphatase 4 regulatory subunit 3A enables IEA TreeGrafter GO_REF:0000118 NCBI chr24:69,219,313...69,270,938
Ensembl chr24:69,218,583...69,270,929 		JBrowse link
G PPP4R3B protein phosphatase 4 regulatory subunit 3B enables IEA TreeGrafter GO_REF:0000118 NCBI chr14:51,285,538...51,356,676
Ensembl chr14:51,285,994...51,355,142 		JBrowse link
protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:130,712,633...130,783,360
Ensembl chr 7:130,712,308...130,763,756 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing enables IEA Ensembl GO_REF:0000107 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391 		JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 enables ISO (PMID:16049005) UniProt PMID:16049005 NCBI chr10:87,389,130...87,473,134 JBrowse link
G ATG13 autophagy related 13 enables ISO (PMID:19225151) UniProt PMID:19225151 NCBI chr 1:18,651,872...18,712,395
Ensembl chr 1:18,652,998...18,712,482 		JBrowse link
G BMP2 bone morphogenetic protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G CAB39 calcium binding protein 39 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:116,749,173...116,860,814
Ensembl chr10:116,798,825...116,861,332 		JBrowse link
G CAB39L calcium binding protein 39 like enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:27,226,012...27,314,413
Ensembl chr 3:27,225,946...27,314,318 		JBrowse link
G CALM1 calmodulin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CALM2 calmodulin 2 enables IEA Ensembl GO_REF:0000107 NCBI chr14:60,027,884...60,042,041
Ensembl chr14:60,027,801...60,044,951
Ensembl chr 6:60,027,801...60,044,951
Ensembl chr24:60,027,801...60,044,951 		JBrowse link
G CALM3 calmodulin 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:39,957,012...39,966,562
Ensembl chr 6:39,957,320...39,966,581
Ensembl chr24:39,957,320...39,966,581
Ensembl chr14:39,957,320...39,966,581 		JBrowse link
G CCDC88A coiled-coil domain containing 88A enables ISO (MGI:3581096|PMID:15753085) UniProt PMID:15753085 MGI:3581096 NCBI chr14:51,484,886...51,615,066
Ensembl chr14:51,484,906...51,610,654 		JBrowse link
G CD40LG CD40 ligand enables IEA Ensembl GO_REF:0000107 NCBI chr  X:111,655,301...111,667,602
Ensembl chr  X:111,655,397...111,666,639 		JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 enables ISO
IEA		 RGD
Ensembl		 PMID:8662984 GO_REF:0000107 RGD:632374 NCBI chr16:26,044,751...26,048,920
Ensembl chr16:26,045,061...26,049,101 		JBrowse link
G DAB2IP DAB2 interacting protein enables ISO (PMID:19903888) GO_Central PMID:19903888 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890 		JBrowse link
G DAZAP2 DAZ associated protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr11:47,437,957...47,443,042
Ensembl chr11:47,437,746...47,443,243 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked enables ISO (PMID:23413191) UniProt PMID:23413191 NCBI chr  X:38,513,251...38,539,982
Ensembl chr  Y:689,380...706,092 		JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 enables IEA Ensembl GO_REF:0000107 NCBI chr23:44,554,027...44,571,738
Ensembl chr23:44,554,705...44,570,352 		JBrowse link
G ETAA1 ETAA1 activator of ATR kinase enables IEA Ensembl GO_REF:0000107 NCBI chr14:39,658,974...39,673,093
Ensembl chr14:39,659,873...39,673,259 		JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase enables IEA Ensembl GO_REF:0000107 NCBI chr16:52,955,411...53,017,263
Ensembl chr16:52,955,714...53,016,909 		JBrowse link
G GCN1 GCN1 activator of EIF2AK4 enables ISO (MGI:5576818|PMID:24333428)
(MGI:6414717|PMID:32324833)		 UniProt PMID:24333428 PMID:32324833 MGI:5576818 MGI:6414717 NCBI chr11:115,479,321...115,545,465
Ensembl chr11:115,477,825...115,545,418 		JBrowse link
G GDF2 growth differentiation factor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:44,087,502...44,092,975
Ensembl chr 9:44,089,358...44,092,484 		JBrowse link
G IGF1 insulin like growth factor 1 enables ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G IGF2 insulin like growth factor 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 enables ISO (PMID:17563371) BHF-UCL PMID:17563371 NCBI chr29:9,363,273...9,485,644
Ensembl chr29:9,362,926...9,485,526 		JBrowse link
G IRGM immunity related GTPase M enables ISO (PMID:28389568)
(PMID:25891078)		 UniProt PMID:25891078 PMID:28389568 NCBI chr23:53,449,576...53,451,373 JBrowse link
G LOC103242599 galectin-9 enables ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chr16:21,421,034...21,439,583 JBrowse link
G LTF lactotransferrin enables IEA Ensembl GO_REF:0000107 NCBI chr22:7,867,332...7,896,403
Ensembl chr22:7,867,286...7,894,521 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 enables ISO (PMID:8388392) UniProt PMID:8388392 NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:3,848,441...3,881,367
Ensembl chr 6:3,848,401...3,881,412 		JBrowse link
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr11:49,581,601...49,600,359
Ensembl chr11:49,582,291...49,600,335 		JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 enables IEA Ensembl GO_REF:0000107 NCBI chr15:3,947,464...4,135,554
Ensembl chr15:3,947,851...4,138,194 		JBrowse link
G MLST8 MTOR associated protein, LST8 homolog enables ISO (PMID:12718876) WB PMID:12718876 NCBI chr 5:2,101,044...2,105,272
Ensembl chr 5:2,101,891...2,105,739 		JBrowse link
G MOB1A MOB kinase activator 1A enables ISO (PMID:18328708) UniProt PMID:18328708 NCBI chr14:33,098,635...33,123,127 JBrowse link
G MOB1B MOB kinase activator 1B enables ISO (PMID:18328708) UniProt PMID:18328708 NCBI chr 7:19,418,464...19,493,969
Ensembl chr 7:19,418,548...19,491,465 		JBrowse link
G MTCP1 mature T cell proliferation 1 enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:129,351,336...129,358,601
Ensembl chr  X:129,352,805...129,353,322 		JBrowse link
G NBN nibrin enables IEA Ensembl GO_REF:0000107 NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028 		JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO Akt (protein kinase B); Ser473, Thr308 RGD PMID:15023862 RGD:1642719 NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059 		JBrowse link
G PARP16 poly(ADP-ribose) polymerase family member 16 enables IEA TreeGrafter GO_REF:0000118 NCBI chr26:18,292,118...18,323,760
Ensembl chr26:18,292,186...18,333,951 		JBrowse link
G PARP6 poly(ADP-ribose) polymerase family member 6 enables IEA TreeGrafter GO_REF:0000118 NCBI chr26:11,182,436...11,214,490
Ensembl chr26:11,182,424...11,214,728 		JBrowse link
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase enables ISO (PMID:16186805) UniProt PMID:16186805 NCBI chr17:34,968,661...34,973,920
Ensembl chr17:34,968,429...34,973,760 		JBrowse link
G RAD50 RAD50 double strand break repair protein enables IEA Ensembl GO_REF:0000107 NCBI chr23:35,375,206...35,458,801
Ensembl chr23:35,375,305...35,458,622 		JBrowse link
G RHEB Ras homolog, mTORC1 binding enables IEA Ensembl GO_REF:0000107 NCBI chr21:119,652,692...119,704,833
Ensembl chr21:119,652,127...119,703,458 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:37,758,531...37,885,323
Ensembl chr 4:37,762,901...37,873,766 		JBrowse link
G SAV1 salvador family WW domain containing protein 1 enables ISO (PMID:29063833), (PMID:35429439) UniProt PMID:29063833 PMID:35429439 NCBI chr24:27,710,256...27,747,638
Ensembl chr24:27,711,970...27,747,647 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:15,967,126...15,995,039 JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:59,357,611...59,362,705
Ensembl chr 3:59,358,394...59,359,341 		JBrowse link
G STRADA STE20 related adaptor alpha enables IEA InterPro GO_REF:0000002 NCBI chr16:57,550,698...57,587,995
Ensembl chr16:57,550,703...57,588,084 		JBrowse link
G STRADB STE20 related adaptor beta enables IEA InterPro GO_REF:0000002 NCBI chr10:87,096,768...87,127,131
Ensembl chr10:87,096,838...87,127,209 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 enables ISO (PMID:37832545) UniProt PMID:37832545 NCBI chr19:21,971,362...22,004,289 JBrowse link
G TAOK1 TAO kinase 1 enables ISO PMID:14517247 ARUK-UCL PMID:14517247 RGD:8553906 NCBI chr16:23,145,629...23,291,694 JBrowse link
G TCL1A TCL1 family AKT coactivator A enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr24:73,556,188...73,570,376
Ensembl chr24:73,566,270...73,570,348 		JBrowse link
G TCL1B TCL1 family AKT coactivator B enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr24:73,548,086...73,554,048
Ensembl chr24:73,548,165...73,552,726 		JBrowse link
G TGFB1 transforming growth factor beta 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr15:56,679,333...56,740,773
Ensembl chr15:56,679,426...56,741,566 		JBrowse link
protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI1 abl interactor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:26,377,822...26,495,665
Ensembl chr 9:26,379,516...26,495,676 		JBrowse link
G AFAP1L2 actin filament associated protein 1 like 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:107,164,687...107,274,433
Ensembl chr 9:107,162,963...107,273,307 		JBrowse link
G CD24 CD24 molecule enables ISO (PMID:11313396) UniProt PMID:11313396 NCBI chr13:66,863,164...66,868,951 JBrowse link
G EGFR epidermal growth factor receptor enables IEA Ensembl GO_REF:0000107 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 enables ISO (PMID:7556068) BHF-UCL PMID:7556068 NCBI chr11:52,020,912...52,043,809
Ensembl chr11:52,021,058...52,044,028 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide enables IEA Ensembl GO_REF:0000107 NCBI chr22:46,326,458...46,332,906
Ensembl chr22:46,325,913...46,330,962 		JBrowse link
G GRM5 glutamate metabotropic receptor 5 enables ISO (PMID:24012003) ARUK-UCL PMID:24012003 RGD:8553716 NCBI chr 1:79,636,636...80,206,471 JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A enables IEA Ensembl GO_REF:0000107 NCBI chr 3:24,820,029...24,884,472
Ensembl chr 3:24,820,035...24,883,432 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer enables IEA Ensembl GO_REF:0000107 NCBI chr 4:52,174,893...52,232,475
Ensembl chr 4:52,174,312...52,214,584 		JBrowse link
G LOC103215829 DNA excision repair protein ERCC-6 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:42,288,702...42,370,045
Ensembl chr 9:42,288,825...42,373,906 		JBrowse link
G NRG1 neuregulin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr15:90,474,367...90,488,814
Ensembl chr15:90,398,660...90,449,346
Ensembl chr15:90,398,660...90,449,346 		JBrowse link
G STAP1 signal transducing adaptor family member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:1,330,761...1,380,503
Ensembl chr 7:1,330,223...1,379,820 		JBrowse link
protein tyrosine phosphatase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD33 CD33 molecule enables ISO (PMID:10556798) ARUK-UCL PMID:10556798 NCBI chr 6:44,149,695...44,166,710
Ensembl chr 6:44,156,925...44,166,487 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 enables IEA Ensembl GO_REF:0000107 NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205 		JBrowse link
G PTPA protein phosphatase 2 phosphatase activator enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:9,017,533...9,056,856
Ensembl chr12:9,019,024...9,056,703 		JBrowse link
G VCAN versican enables ISO (PMID:21976490) MGI PMID:21976490 NCBI chr 4:77,581,627...77,692,495
Ensembl chr 4:77,593,449...77,690,616 		JBrowse link
receptor signaling protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase enables ISO (PMID:30061385), (PMID:34646012) UniProt PMID:30061385 PMID:34646012 NCBI chr14:77,632,809...78,408,307 JBrowse link
G ALK ALK receptor tyrosine kinase enables IEA Ensembl GO_REF:0000107 Ensembl chr14:78,200,889...78,406,094 JBrowse link
G ALKAL1 ALK and LTK ligand 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chr 8:48,641,163...48,672,392
Ensembl chr 8:48,645,771...48,669,954 		JBrowse link
G ALKAL2 ALK and LTK ligand 2 enables IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr14:107,438,932...107,448,066
Ensembl chr14:107,439,646...107,444,580 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 enables IEA Ensembl GO_REF:0000107 NCBI chr16:29,351,214...29,361,317 JBrowse link
G LTK leukocyte receptor tyrosine kinase enables IEA Ensembl GO_REF:0000107 NCBI chr26:41,489,867...41,502,314
Ensembl chr26:41,490,902...41,501,956 		JBrowse link
recombinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PSMC3IP PSMC3 interacting protein enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:63,709,351...63,715,338
Ensembl chr16:63,709,982...63,714,804 		JBrowse link
RNA lariat debranching enzyme activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CWF19L1 CWF19 like cell cycle control factor 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:93,266,730...93,301,095
Ensembl chr 9:93,266,799...93,295,320 		JBrowse link
G LOC103221207 CWF19-like protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr15:9,907,782...9,909,518 JBrowse link
sphingomyelin phosphodiesterase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NSMAF neutral sphingomyelinase activation associated factor ISO RGD PMID:12637370 RGD:1299578 NCBI chr 8:54,565,714...54,642,896
Ensembl chr 8:54,567,121...54,642,054 		JBrowse link
G STX4 syntaxin 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:27,725,121...27,734,442
Ensembl chr 5:27,724,495...27,732,736 		JBrowse link
superoxide-generating NADPH oxidase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NCF1 neutrophil cytosolic factor 1 enables ISO
IEA		 RGD
InterPro		 PMID:16040349 GO_REF:0000002 RGD:1600567 NCBI chr28:8,334,172...8,349,828
Ensembl chr28:8,332,772...8,349,804 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr25:45,770,370...45,807,064
Ensembl chr25:45,770,641...45,806,515 		JBrowse link
G NCF4 neutrophil cytosolic factor 4 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr19:19,560,047...19,579,342
Ensembl chr19:19,566,562...19,579,352 		JBrowse link
G NOXA1 NADPH oxidase activator 1 enables ISO (PMID:12473664)
(PMID:20609497)
(PMID:16636067)		 MGI
UniProt
BHF-UCL		 PMID:12473664 PMID:16636067 PMID:20609497 NCBI chr12:758,107...769,252
Ensembl chr12:758,152...769,095 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:1,874,801...1,878,557
Ensembl chr 5:1,874,937...1,877,044 		JBrowse link
G PDGFB platelet derived growth factor subunit B enables IEA Ensembl GO_REF:0000107 NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395 		JBrowse link
G SH3PXD2A SH3 and PX domains 2A enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:96,645,955...96,898,749 JBrowse link
G SH3PXD2B SH3 and PX domains 2B enables IEA TreeGrafter GO_REF:0000118 NCBI chr23:74,498,389...74,613,296
Ensembl chr23:74,498,381...74,613,123 		JBrowse link
transmembrane receptor protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKAL1 ALK and LTK ligand 1 enables ISO (PMID:34646012), (PMID:34819673) UniProt PMID:34646012 PMID:34819673 NCBI chr 8:48,641,163...48,672,392
Ensembl chr 8:48,645,771...48,669,954 		JBrowse link
G ALKAL2 ALK and LTK ligand 2 enables IEA Ensembl GO_REF:0000107 NCBI chr14:107,438,932...107,448,066
Ensembl chr14:107,439,646...107,444,580 		JBrowse link
G ANGPT4 angiopoietin 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:55,619,463...55,654,843
Ensembl chr 2:55,620,694...55,654,001 		JBrowse link
G AREG amphiregulin enables IEA Ensembl GO_REF:0000107 NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162 		JBrowse link
G BTC betacellulin enables IEA Ensembl GO_REF:0000107 NCBI chr 7:23,283,269...23,333,373
Ensembl chr 7:23,281,862...23,308,287 		JBrowse link
G DGKQ diacylglycerol kinase theta enables IEA Ensembl GO_REF:0000107 NCBI chr27:47,804,904...47,819,291
Ensembl chr27:47,805,017...47,817,583 		JBrowse link
G EGF epidermal growth factor enables ISO (PMID:11336639)
(PMID:11823423), (PMID:12761849), (PMID:14627991), (PMID:22822073), (PMID:6248866), (PMID:7752576), (PMID:9529375)		 MGI PMID:6248866 PMID:7752576 PMID:9529375 PMID:11336639 PMID:11823423 More... NCBI chr 7:57,810,110...57,911,361
Ensembl chr 7:57,811,728...57,911,516 		JBrowse link
G EGFR epidermal growth factor receptor enables ISO (PMID:7678348) MGI PMID:7678348 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G EPGN epithelial mitogen enables ISO (PMID:23899604), (PMID:24891618)
(PMID:11278323)		 MGI PMID:11278323 PMID:23899604 PMID:24891618 NCBI chr 7:22,842,830...22,852,867
Ensembl chr 7:22,844,202...22,853,104 		JBrowse link
G EREG epiregulin enables IEA Ensembl GO_REF:0000107 NCBI chr 7:22,898,998...22,924,922
Ensembl chr 7:22,901,862...22,920,678 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist enables ISO (MGI:4845816|PMID:20660291) BHF-UCL PMID:20660291 MGI:4845816 NCBI chr26:50,152,097...50,169,760 JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist enables IEA Ensembl GO_REF:0000107 Ensembl chr26:50,155,496...50,156,047 JBrowse link
G HBEGF heparin binding EGF like growth factor enables ISO (PMID:8702723)
(PMID:21946538)
(PMID:12621152)
(PMID:12621152), (PMID:16357442)		 MGI PMID:8702723 PMID:12621152 PMID:16357442 PMID:21946538 NCBI chr23:42,981,640...42,995,116
Ensembl chr23:42,981,640...42,994,995 		JBrowse link
G IGF1 insulin like growth factor 1 enables ISO (PMID:35647546)
(PMID:32697974)		 MGI PMID:32697974 PMID:35647546 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G IGF2 insulin like growth factor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G LOC119623289 diacylglycerol kinase theta enables IEA Ensembl GO_REF:0000107
G NGF nerve growth factor enables ISO (MGI:5426777|PMID:19036963), (PMID:27655914) MGI PMID:19036963 PMID:27655914 MGI:5426777 NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833 		JBrowse link
G TGFA transforming growth factor alpha enables IEA Ensembl GO_REF:0000107 NCBI chr14:36,545,641...36,654,213
Ensembl chr14:36,545,875...36,648,237 		JBrowse link
G VEGFA vascular endothelial growth factor A enables ISO (PMID:20497126) BHF-UCL PMID:20497126 NCBI chr17:28,377,959...28,394,508 JBrowse link
G VEGFA vascular endothelial growth factor A enables IEA Ensembl GO_REF:0000107 Ensembl chr17:28,379,880...28,393,995 JBrowse link
tRNA methyltransferase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRMT112 tRNA methyltransferase activator subunit 11-2 enables ISO (PMID:34669960) UniProt PMID:34669960 NCBI chr 1:9,916,884...9,918,790 JBrowse link
G WDR4 WD repeat domain 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:86,715,939...86,745,972
Ensembl chr 2:86,716,922...86,745,547 		JBrowse link
tyrosine 3-monooxygenase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase enables IEA Ensembl GO_REF:0000107 NCBI chr20:123,776,084...123,808,031
Ensembl chr20:123,776,297...123,798,434 		JBrowse link
ubiquitin ligase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase enables ISO (PMID:12820959) ParkinsonsUK-UCL PMID:12820959 NCBI chr 9:94,333,046...94,581,327
Ensembl chr 9:94,376,055...94,574,678 		JBrowse link
G CDC20 cell division cycle 20 enables IEA TreeGrafter GO_REF:0000118 NCBI chr20:89,449,008...89,453,263
Ensembl chr20:89,444,165...89,453,044 		JBrowse link
G CDC20B cell division cycle 20B enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:51,349,486...51,408,437
Ensembl chr 4:51,351,574...51,406,488 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B enables ISO (PMID:16209941) DisProt PMID:16209941 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G ENTREP1 endosomal transmembrane epsin interactor 1 enables ISO (PMID:34927784) UniProt PMID:34927784 NCBI chr12:80,421,600...80,485,566
Ensembl chr12:80,421,683...80,484,918 		JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:3,272,247...3,300,370
Ensembl chr 6:3,288,407...3,298,464 		JBrowse link
G LOC103247827 ranBP-type and C3HC4-type zinc finger-containing protein 1 enables ISO (PMID:34755089) MGI PMID:34755089 NCBI chr 2:35,537,387...35,559,628
Ensembl chr 2:35,538,127...35,560,129 		JBrowse link
G PEX12 peroxisomal biogenesis factor 12 enables ISO (PMID:24662292) UniProt PMID:24662292 NCBI chr16:29,049,206...29,054,718 JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:8,920,860...8,935,943
Ensembl chr 6:8,920,785...8,936,033 		JBrowse link
ubiquitin-protein transferase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMI1 BMI1 proto-oncogene, polycomb ring finger enables ISO (PMID:16359901) MGI PMID:16359901 NCBI chr 9:22,095,592...22,104,894 JBrowse link
G CBX8 chromobox 8 enables IEA Ensembl GO_REF:0000107 NCBI chr16:71,755,598...71,760,611
Ensembl chr16:71,755,627...71,760,632 		JBrowse link
G CDC20 cell division cycle 20 enables IEA InterPro GO_REF:0000002 NCBI chr20:89,449,008...89,453,263
Ensembl chr20:89,444,165...89,453,044 		JBrowse link
G CDC20B cell division cycle 20B enables IEA InterPro GO_REF:0000002 NCBI chr 4:51,349,486...51,408,437
Ensembl chr 4:51,351,574...51,406,488 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 enables IEA InterPro GO_REF:0000002 NCBI chr 6:3,272,247...3,300,370
Ensembl chr 6:3,288,407...3,298,464 		JBrowse link
G PCGF2 polycomb group ring finger 2 NOT|enables ISO (PMID:16359901) MGI PMID:16359901 NCBI chr16:67,447,181...67,461,829
Ensembl chr16:67,455,292...67,460,509 		JBrowse link
G RING1 ring finger protein 1 enables ISO (PMID:16359901) MGI PMID:16359901 NCBI chr17:38,862,411...38,866,631
Ensembl chr17:38,860,729...38,866,371 		JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 enables ISO (PMID:12628165) ParkinsonsUK-UCL PMID:12628165 NCBI chr19:4,485,960...4,538,838 JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N enables ISO (PMID:17349954) HGNC-UCL PMID:17349954 NCBI chr11:88,810,505...88,842,895 JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N enables IEA Ensembl GO_REF:0000107 Ensembl chr11:88,812,182...88,842,625 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17958
    molecular function regulator activity 1849
      molecular function activator activity 981
        enzyme activator activity 508
          DNA polymerase processivity factor activity 3
          DNA strand exchange activator activity 0
          DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity 0
          GTPase activator activity 195
          L-dopa decarboxylase activator activity 1
          acetyltransferase activator activity 4
          cyclase activator activity + 12
          cyclic nucleotide phosphodiesterase activator activity 0
          guanyl nucleotide exchange factor activator activity 0
          kinase activator activity + 139
          lipase activator activity + 27
          mRNA phosphatase activator activity 0
          nuclease activator activity + 2
          ornithine decarboxylase activator activity 3
          peptidase activator activity + 50
          phosphatase activator activity + 18
          phosphatidylcholine-sterol O-acyltransferase activator activity 4
          polynucleotide adenylyltransferase activator activity 0
          recombinase activator activity 1
          ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity 0
          sphingolipid activator protein activity 0
          superoxide-generating NADPH oxidase activator activity 8
          tRNA ligase activator activity 0
          tRNA methyltransferase activator activity 2
          tryptophan hydroxylase activator activity 0
          tyrosine 3-monooxygenase activator activity 1
          ubiquitin-protein transferase activator activity + 17
          urease activator activity 0
paths to the root