CCNT2 (cyclin T2) - Rat Genome Database

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Gene: CCNT2 (cyclin T2) Chlorocebus sabaeus
Analyze
Symbol: CCNT2
Name: cyclin T2
RGD ID: 18510763
Description: ENCODES a protein that exhibits 7SK snRNA binding (ortholog); chromatin binding (ortholog); protein kinase binding (ortholog); INVOLVED IN early viral transcription (ortholog); late viral transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH genetic disease (ortholog); primary ovarian insufficiency (ortholog); FOUND IN cyclin/CDK positive transcription elongation factor complex (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin-T2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11019,145,163 - 19,183,777 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1019,145,161 - 19,180,917 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660613,318,380 - 3,358,919 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CCNT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11019,145,163 - 19,183,777 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1019,145,161 - 19,180,917 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660613,318,380 - 3,358,919 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CCNT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382134,918,822 - 134,959,342 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2134,918,235 - 134,959,342 (+)EnsemblGRCh38hg38GRCh38
GRCh372135,676,392 - 135,716,912 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362135,392,863 - 135,431,057 (+)NCBINCBI36Build 36hg18NCBI36
Build 342135,510,124 - 135,548,316NCBI
Celera2129,389,316 - 129,427,507 (+)NCBICelera
Cytogenetic Map2q21.3NCBI
HuRef2127,668,086 - 127,708,608 (+)NCBIHuRef
CHM1_12135,681,212 - 135,721,765 (+)NCBICHM1_1
T2T-CHM13v2.02135,359,158 - 135,399,741 (+)NCBIT2T-CHM13v2.0
Ccnt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391127,701,901 - 127,732,574 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1127,701,901 - 127,735,798 (+)EnsemblGRCm39 Ensembl
GRCm381127,774,164 - 127,804,837 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1127,774,164 - 127,808,061 (+)EnsemblGRCm38mm10GRCm38
MGSCv371129,670,741 - 129,701,414 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,601,710 - 129,632,383 (+)NCBIMGSCv36mm8
Celera1130,415,607 - 130,446,300 (+)NCBICelera
Cytogenetic Map1E3NCBI
cM Map155.8NCBI
Ccnt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81341,804,007 - 41,845,641 (+)NCBIGRCr8
mRatBN7.21339,251,573 - 39,293,172 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1339,251,573 - 39,292,019 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1341,837,188 - 41,877,612 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01343,125,279 - 43,165,709 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01340,388,273 - 40,428,718 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01344,475,959 - 44,516,892 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,475,970 - 44,515,739 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01349,560,733 - 49,601,670 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,498,884 - 40,540,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11340,516,379 - 40,554,138 (-)NCBI
Celera1339,627,795 - 39,667,593 (+)NCBICelera
Cytogenetic Map13q13NCBI
Ccnt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554402,424,978 - 2,470,811 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554402,424,976 - 2,468,388 (+)NCBIChiLan1.0ChiLan1.0
CCNT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21339,972,719 - 40,010,898 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B39,987,689 - 40,025,866 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B24,903,389 - 24,943,122 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B138,994,866 - 139,035,301 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B138,994,868 - 139,035,301 (+)Ensemblpanpan1.1panPan2
CCNT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11937,743,442 - 37,787,875 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1937,743,235 - 37,783,220 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1937,983,447 - 38,027,889 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01939,188,742 - 39,233,204 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1939,188,029 - 39,231,246 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11937,831,213 - 37,875,647 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01937,992,184 - 38,036,607 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01939,227,340 - 39,271,785 (+)NCBIUU_Cfam_GSD_1.0
Ccnt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303100,780,261 - 100,818,026 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646940,803,819 - 40,837,433 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646940,799,428 - 40,837,462 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,974,038 - 17,021,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,974,364 - 17,021,293 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21519,426,238 - 19,473,794 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ccnt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473234,307,124 - 34,357,354 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 18 60
Low 2
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000014505   ⟹   ENSCSAP00000012477
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1019,145,161 - 19,180,917 (+)Ensembl
RefSeq Acc Id: XM_007964807   ⟹   XP_007962998
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11019,145,169 - 19,183,777 (+)NCBI
Vero_WHO_p1.0NW_0236660613,318,380 - 3,358,918 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007964808   ⟹   XP_007962999
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11019,145,169 - 19,183,777 (+)NCBI
Vero_WHO_p1.0NW_0236660613,318,380 - 3,358,918 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007964809   ⟹   XP_007963000
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11019,169,677 - 19,183,777 (+)NCBI
Vero_WHO_p1.0NW_0236660613,318,380 - 3,358,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037988073   ⟹   XP_037844001
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660613,318,380 - 3,358,915 (-)NCBI
RefSeq Acc Id: XM_037988074   ⟹   XP_037844002
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660613,318,380 - 3,358,915 (-)NCBI
RefSeq Acc Id: XR_490798
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11019,145,163 - 19,174,172 (+)NCBI
Vero_WHO_p1.0NW_0236660613,322,541 - 3,358,919 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007962998 (Get FASTA)   NCBI Sequence Viewer  
  XP_007962999 (Get FASTA)   NCBI Sequence Viewer  
  XP_007963000 (Get FASTA)   NCBI Sequence Viewer  
  XP_037844001 (Get FASTA)   NCBI Sequence Viewer  
  XP_037844002 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012477.1
RefSeq Acc Id: XP_007962998   ⟸   XM_007964807
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RV38 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007962999   ⟸   XM_007964808
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RV38 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007963000   ⟸   XM_007964809
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000012477   ⟸   ENSCSAT00000014505
RefSeq Acc Id: XP_037844002   ⟸   XM_037988074
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037844001   ⟸   XM_037988073
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016413 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014505.1 UniProtKB/TrEMBL
Gene3D-CATH Cyclin-like UniProtKB/TrEMBL
InterPro Cyclin-like UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/TrEMBL
  Cyclin/Ssn8 UniProtKB/TrEMBL
  CYCLIN_CCNT2_rpt1 UniProtKB/TrEMBL
  CYCLIN_CCNT2_rpt2 UniProtKB/TrEMBL
  Cyclin_N UniProtKB/TrEMBL
NCBI Gene CCNT2 ENTREZGENE
PANTHER PTHR10026 UniProtKB/TrEMBL
  PTHR10026:SF43 UniProtKB/TrEMBL
Pfam Cyclin_N UniProtKB/TrEMBL
  CycT2-like_C UniProtKB/TrEMBL
SMART CYCLIN UniProtKB/TrEMBL
Superfamily-SCOP SSF47954 UniProtKB/TrEMBL
UniProt A0A0D9RV38 ENTREZGENE, UniProtKB/TrEMBL