LLGL1 (LLGL scribble cell polarity complex component 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: LLGL1 (LLGL scribble cell polarity complex component 1) Chlorocebus sabaeus
Analyze
Symbol: LLGL1
Name: LLGL scribble cell polarity complex component 1
RGD ID: 18428378
Description: ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN axonogenesis (ortholog); maintenance of apical/basal cell polarity (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Birt-Hogg-Dube syndrome (ortholog); Breast Neoplasms (ortholog); FOUND IN axon (ortholog); basolateral plasma membrane (ortholog); cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lethal(2) giant larvae protein homolog 1; LLGL1, scribble cell polarity complex component
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11617,266,648 - 17,285,460 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1617,266,684 - 17,284,076 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660593,617,199 - 3,638,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LLGL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11617,266,648 - 17,285,460 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1617,266,684 - 17,284,076 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660593,617,199 - 3,638,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LLGL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381718,225,635 - 18,244,875 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1718,225,635 - 18,244,875 (+)EnsemblGRCh38hg38GRCh38
GRCh371718,128,949 - 18,148,189 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361718,069,661 - 18,088,914 (+)NCBINCBI36Build 36hg18NCBI36
Build 341718,069,715 - 18,087,963NCBI
Celera1719,074,368 - 19,089,303 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1717,886,506 - 17,901,442 (+)NCBIHuRef
CHM1_11718,137,711 - 18,156,955 (+)NCBICHM1_1
T2T-CHM13v2.01718,172,434 - 18,191,679 (+)NCBIT2T-CHM13v2.0
Llgl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,590,501 - 60,605,012 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,590,549 - 60,605,012 (+)EnsemblGRCm39 Ensembl
GRCm381160,699,672 - 60,714,186 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,699,723 - 60,714,186 (+)EnsemblGRCm38mm10GRCm38
MGSCv371160,513,192 - 60,527,690 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361161,130,925 - 61,145,271 (+)NCBIMGSCv36mm8
MGSCv361160,516,035 - 60,530,381 (+)NCBIMGSCv36mm8
Cytogenetic Map11B2NCBI
cM Map1137.81NCBI
Llgl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,878,936 - 45,893,609 (+)NCBIGRCr8
mRatBN7.21045,379,423 - 45,394,096 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,379,515 - 45,394,094 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,080,221 - 50,094,720 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,570,609 - 49,585,108 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,074,208 - 45,088,705 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,940,873 - 46,955,524 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,940,965 - 46,954,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,713,910 - 46,728,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,845,810 - 46,859,100 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,859,432 - 46,872,723 (+)NCBI
Celera1044,634,872 - 44,649,254 (+)NCBICelera
Cytogenetic Map10q22NCBI
Llgl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547811,075,399 - 11,089,839 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547811,075,399 - 11,089,818 (-)NCBIChiLan1.0ChiLan1.0
LLGL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21953,021,328 - 53,040,580 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11757,732,297 - 57,751,542 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01732,770,511 - 32,789,756 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11737,966,100 - 37,982,466 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1737,966,100 - 37,985,103 (-)Ensemblpanpan1.1panPan2
LLGL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1541,314,807 - 41,332,687 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl541,315,152 - 41,332,896 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha541,454,283 - 41,472,092 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0541,421,547 - 41,439,311 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl541,421,553 - 41,439,596 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1541,389,367 - 41,407,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0541,336,840 - 41,354,607 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0541,528,638 - 41,546,442 (-)NCBIUU_Cfam_GSD_1.0
Llgl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560261,082,262 - 61,099,934 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367411,770,620 - 1,788,356 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367411,770,797 - 1,784,716 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LLGL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,487,343 - 60,500,447 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,487,337 - 60,500,423 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Llgl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248493,227,758 - 3,245,118 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248493,227,518 - 3,245,137 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000006217   ⟹   ENSCSAP00000004427
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1617,266,684 - 17,284,076 (+)Ensembl
RefSeq Acc Id: XM_037987905   ⟹   XP_037843833
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660593,617,199 - 3,638,591 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037843833 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004427.1
Ensembl Acc Id: ENSCSAP00000004427   ⟸   ENSCSAT00000006217
RefSeq Acc Id: XP_037843833   ⟸   XM_037987905


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008171 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006217.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Lethal2_giant UniProtKB/TrEMBL
  LLGL2 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103242487 UniProtKB/TrEMBL
NCBI Gene LLGL1 ENTREZGENE
PANTHER LETHAL 2 GIANT LARVAE PROTEIN UniProtKB/TrEMBL
  LETHAL(2) GIANT LARVAE PROTEIN HOMOLOG 1 UniProtKB/TrEMBL
Pfam LLGL UniProtKB/TrEMBL
PRINTS LETHAL2GIANT UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9R738_CHLSB UniProtKB/TrEMBL