Llgl1 (LLGL scribble cell polarity complex component 1) - Rat Genome Database

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Gene: Llgl1 (LLGL scribble cell polarity complex component 1) Chinchilla lanigera
Analyze
Symbol: Llgl1
Name: LLGL scribble cell polarity complex component 1
RGD ID: 8897463
Description: ENCODES a protein that exhibits GTPase activator activity (ortholog); protein kinase binding (ortholog); small GTPase binding (ortholog); INVOLVED IN axonogenesis (ortholog); cortical actin cytoskeleton organization (ortholog); Golgi to plasma membrane transport (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Birt-Hogg-Dube syndrome (ortholog); Breast Neoplasms (ortholog); FOUND IN axon (ortholog); basolateral plasma membrane (ortholog); cortical actin cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lethal giant larvae homolog 1 (Drosophila); lethal(2) giant larvae protein homolog 1; LLGL1, scribble cell polarity complex component
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547811,075,399 - 11,089,839 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547811,075,399 - 11,089,818 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Llgl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547811,075,399 - 11,089,839 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547811,075,399 - 11,089,818 (-)NCBIChiLan1.0ChiLan1.0
LLGL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381718,225,635 - 18,244,875 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1718,225,635 - 18,244,875 (+)EnsemblGRCh38hg38GRCh38
GRCh371718,128,949 - 18,148,189 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361718,069,661 - 18,088,914 (+)NCBINCBI36Build 36hg18NCBI36
Build 341718,069,715 - 18,087,963NCBI
Celera1719,074,368 - 19,089,303 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1717,886,506 - 17,901,442 (+)NCBIHuRef
CHM1_11718,137,711 - 18,156,955 (+)NCBICHM1_1
T2T-CHM13v2.01718,172,434 - 18,191,679 (+)NCBIT2T-CHM13v2.0
Llgl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,590,501 - 60,605,012 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,590,549 - 60,605,012 (+)EnsemblGRCm39 Ensembl
GRCm381160,699,672 - 60,714,186 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,699,723 - 60,714,186 (+)EnsemblGRCm38mm10GRCm38
MGSCv371160,513,192 - 60,527,690 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361161,130,925 - 61,145,271 (+)NCBIMGSCv36mm8
MGSCv361160,516,035 - 60,530,381 (+)NCBIMGSCv36mm8
Cytogenetic Map11B2NCBI
cM Map1137.81NCBI
Llgl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,878,936 - 45,893,609 (+)NCBIGRCr8
mRatBN7.21045,379,423 - 45,394,096 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,379,515 - 45,394,094 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,080,221 - 50,094,720 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,570,609 - 49,585,108 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,074,208 - 45,088,705 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,940,873 - 46,955,524 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,940,965 - 46,954,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,713,910 - 46,728,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,845,810 - 46,859,100 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,859,432 - 46,872,723 (+)NCBI
Celera1044,634,872 - 44,649,254 (+)NCBICelera
Cytogenetic Map10q22NCBI
LLGL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21953,021,328 - 53,040,580 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11757,732,297 - 57,751,542 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01732,770,511 - 32,789,756 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11737,966,100 - 37,982,466 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1737,966,100 - 37,985,103 (-)Ensemblpanpan1.1panPan2
LLGL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1541,314,807 - 41,332,687 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl541,315,152 - 41,332,896 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha541,454,283 - 41,472,092 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0541,421,547 - 41,439,311 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl541,421,553 - 41,439,596 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1541,389,367 - 41,407,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0541,336,840 - 41,354,607 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0541,528,638 - 41,546,442 (-)NCBIUU_Cfam_GSD_1.0
Llgl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560261,082,262 - 61,099,934 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367411,770,620 - 1,788,356 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367411,770,797 - 1,784,716 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LLGL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,487,343 - 60,500,447 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,487,337 - 60,500,423 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LLGL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11617,266,648 - 17,285,460 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1617,266,684 - 17,284,076 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660593,617,199 - 3,638,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Llgl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248493,227,758 - 3,245,118 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248493,227,518 - 3,245,137 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005200   ⟹   ENSCLAP00000005107
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547811,075,399 - 11,089,839 (-)Ensembl
RefSeq Acc Id: XM_005402281   ⟹   XP_005402338
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547811,075,399 - 11,089,818 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005402338 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005107
  ENSCLAP00000005107.1
Reference Protein Sequences
RefSeq Acc Id: XP_005402338   ⟸   XM_005402281
- UniProtKB: A0A8C2USG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005107   ⟸   ENSCLAT00000005200
Protein Domains
Lethal giant larvae homologue


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003625 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005200 ENTREZGENE
  ENSCLAT00000005200.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Lethal2_giant UniProtKB/TrEMBL
  LLGL2 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Llgl1 ENTREZGENE
PANTHER LETHAL 2 GIANT LARVAE PROTEIN UniProtKB/TrEMBL
  LETHAL(2) GIANT LARVAE PROTEIN HOMOLOG 1 UniProtKB/TrEMBL
Pfam LLGL UniProtKB/TrEMBL
PRINTS LETHAL2GIANT UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A8C2USG5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-29 Llgl1  LLGL scribble cell polarity complex component 1    LLGL1, scribble cell polarity complex component  Symbol and/or name change 5135510 APPROVED
2016-08-03 Llgl1  LLGL1, scribble cell polarity complex component    lethal giant larvae homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED