RGS18 (regulator of G protein signaling 18) - Rat Genome Database

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Gene: RGS18 (regulator of G protein signaling 18) Chlorocebus sabaeus
Analyze
Symbol: RGS18
Name: regulator of G protein signaling 18
RGD ID: 18725993
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); GTPase activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); regulation of G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); Hyperparathyroidism 1 (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12537,241,785 - 37,269,603 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2537,240,813 - 37,269,655 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605538,217,288 - 38,245,426 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
RGS18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12537,241,785 - 37,269,603 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2537,240,813 - 37,269,655 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605538,217,288 - 38,245,426 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RGS18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381192,158,462 - 192,185,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1192,158,462 - 192,185,815 (+)EnsemblGRCh38hg38GRCh38
GRCh371192,127,592 - 192,154,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361190,394,215 - 190,421,568 (+)NCBINCBI36Build 36hg18NCBI36
Build 341188,859,248 - 188,886,600NCBI
Celera1165,237,273 - 165,264,630 (+)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1163,363,810 - 163,391,169 (+)NCBIHuRef
CHM1_11193,549,309 - 193,576,659 (+)NCBICHM1_1
T2T-CHM13v2.01191,505,098 - 191,532,461 (+)NCBIT2T-CHM13v2.0
Rgs18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391144,628,430 - 144,651,165 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1144,628,421 - 144,651,173 (-)EnsemblGRCm39 Ensembl
GRCm381144,752,683 - 144,775,427 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1144,752,683 - 144,775,435 (-)EnsemblGRCm38mm10GRCm38
MGSCv371146,599,971 - 146,622,551 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361146,515,059 - 146,537,639 (-)NCBIMGSCv36mm8
Celera1147,304,314 - 147,326,917 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.99NCBI
Rgs18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81359,043,431 - 59,066,342 (-)NCBIGRCr8
mRatBN7.21356,493,134 - 56,516,045 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1356,494,010 - 56,516,098 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1359,074,012 - 59,095,539 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01360,309,962 - 60,331,603 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01357,606,095 - 57,627,629 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01361,564,381 - 61,591,139 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1361,565,483 - 61,591,139 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01366,552,686 - 66,578,436 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41358,607,898 - 58,629,597 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11358,621,913 - 58,643,688 (-)NCBI
Celera1356,557,495 - 56,580,317 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rgs18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540629,573,035 - 29,594,991 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540629,573,127 - 29,594,991 (+)NCBIChiLan1.0ChiLan1.0
RGS18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2157,603,789 - 57,632,565 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1157,267,876 - 57,296,649 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,620,514 - 167,648,917 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11171,916,342 - 171,943,674 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1171,915,531 - 171,943,674 (+)Ensemblpanpan1.1panPan2
RGS18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1386,729,056 - 6,743,522 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl386,730,328 - 6,743,396 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha386,826,247 - 6,840,720 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0386,746,875 - 6,761,345 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl386,745,650 - 6,761,233 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1386,747,253 - 6,761,824 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0387,111,284 - 7,125,753 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0387,349,501 - 7,364,192 (-)NCBIUU_Cfam_GSD_1.0
Rgs18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934481,606,894 - 81,630,645 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936638514,506 - 535,422 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936638514,412 - 535,417 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl101,520,872 - 1,539,663 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1101,520,866 - 1,539,776 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2103,286,947 - 3,305,869 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rgs18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248141,502,363 - 1,524,558 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248141,502,055 - 1,524,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20
Low 35 60
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007989128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000011445   ⟹   ENSCSAP00000009514
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2537,240,813 - 37,269,655 (-)Ensembl
RefSeq Acc Id: XM_007989128   ⟹   XP_007987319
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12537,241,785 - 37,269,603 (-)NCBI
Vero_WHO_p1.0NW_02366605538,217,288 - 38,245,426 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007987319 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009514
  ENSCSAP00000009514.1
Reference Protein Sequences
RefSeq Acc Id: XP_007987319   ⟸   XM_007989128
- UniProtKB: A0A0D9RLM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000009514   ⟸   ENSCSAT00000011445


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013348 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011445.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
InterPro RGS UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
KEGG Report csab:103230404 UniProtKB/TrEMBL
NCBI Gene RGS18 ENTREZGENE
PANTHER PTHR10845:SF155 UniProtKB/TrEMBL
  REGULATOR OF G PROTEIN SIGNALING UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt A0A0D9RLM5 ENTREZGENE, UniProtKB/TrEMBL