CHN1 (chimerin 1) - Rat Genome Database

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Gene: CHN1 (chimerin 1) Chlorocebus sabaeus
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Symbol: CHN1
Name: chimerin 1
RGD ID: 18717227
Description: ENCODES a protein that exhibits ephrin receptor binding (inferred); GTPase activator activity (inferred); metal ion binding (inferred); INVOLVED IN ephrin receptor signaling pathway (inferred); motor neuron axon guidance (inferred); regulation of axonogenesis (inferred); ASSOCIATED WITH autosomal dominant Robinow syndrome 2 (ortholog); Dandy-Walker syndrome (ortholog); Duane retraction syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: N-chimaerin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11060,334,829 - 60,540,309 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1060,331,214 - 60,488,785 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CHN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11060,334,829 - 60,540,309 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1060,331,214 - 60,488,785 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CHN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382174,798,809 - 175,005,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2174,798,809 - 175,005,381 (-)EnsemblGRCh38hg38GRCh38
GRCh372175,663,537 - 175,870,109 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362175,372,338 - 175,578,361 (-)NCBINCBI36Build 36hg18NCBI36
Build 342175,489,740 - 175,695,461NCBI
Celera2169,277,589 - 169,483,716 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2167,544,975 - 167,750,776 (-)NCBIHuRef
CHM1_12175,670,072 - 175,876,103 (-)NCBICHM1_1
T2T-CHM13v2.02175,287,561 - 175,494,136 (-)NCBIT2T-CHM13v2.0
Chn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39273,441,004 - 73,605,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl273,441,004 - 73,605,690 (-)EnsemblGRCm39 Ensembl
GRCm38273,610,660 - 73,775,367 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl273,610,660 - 73,775,346 (-)EnsemblGRCm38mm10GRCm38
MGSCv37273,448,717 - 73,613,403 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36273,411,584 - 73,461,205 (-)NCBIMGSCv36mm8
Celera275,297,418 - 75,408,740 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map243.78NCBI
Chn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,917,329 - 79,084,040 (-)NCBIGRCr8
mRatBN7.2358,509,822 - 58,676,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx361,903,426 - 62,070,497 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0370,487,079 - 70,654,162 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0368,252,108 - 68,419,189 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0360,512,360 - 60,668,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl360,513,077 - 60,611,924 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0366,992,186 - 67,147,012 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4356,144,053 - 56,186,665 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1356,040,424 - 56,083,037 (-)NCBI
Celera358,037,858 - 58,080,474 (-)NCBICelera
Cytogenetic Map3q23NCBI
Chn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955449574,407 - 635,566 (+)NCBIChiLan1.0ChiLan1.0
CHN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21377,461,632 - 77,672,824 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B77,476,538 - 77,685,703 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B62,074,405 - 62,283,013 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B179,527,971 - 179,694,524 (-)NCBIpanpan1.1PanPan1.1panPan2
CHN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13618,785,470 - 18,990,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3618,786,073 - 18,980,993 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3618,794,209 - 18,999,749 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03618,922,240 - 19,128,093 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3618,921,400 - 19,118,599 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13618,998,481 - 19,204,056 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03618,997,206 - 19,202,881 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03619,107,993 - 19,313,290 (-)NCBIUU_Cfam_GSD_1.0
Chn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303135,953,039 - 136,123,796 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365094,506,311 - 4,678,313 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365094,507,042 - 4,677,681 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1580,730,716 - 80,927,746 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11580,731,243 - 80,927,746 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21589,940,525 - 90,059,474 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Chn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478711,989,587 - 12,176,925 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000012627   ⟹   ENSCSAP00000010659
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1060,331,214 - 60,488,785 (-)Ensembl
RefSeq Acc Id: XM_007965409   ⟹   XP_007963600
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11060,334,829 - 60,540,243 (-)NCBI
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007965412   ⟹   XP_007963603
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11060,334,829 - 60,540,243 (-)NCBI
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007965413   ⟹   XP_007963604
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11060,334,829 - 60,488,779 (-)NCBI
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038001906   ⟹   XP_037857834
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBI
RefSeq Acc Id: XM_038001907   ⟹   XP_037857835
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666040139,193,144 - 139,270,190 (+)NCBI
RefSeq Acc Id: XM_038001908   ⟹   XP_037857836
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666040139,223,792 - 139,270,190 (+)NCBI
RefSeq Acc Id: XP_007963603   ⟸   XM_007965412
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007963600   ⟸   XM_007965409
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007963604   ⟸   XM_007965413
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RPX0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000010659   ⟸   ENSCSAT00000012627
RefSeq Acc Id: XP_037857834   ⟸   XM_038001906
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037857835   ⟸   XM_038001907
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037857836   ⟸   XM_038001908
- Peptide Label: isoform X6


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014539 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012627.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  Chimaerin_SH2 UniProtKB/TrEMBL
  CHN1/CHN2 UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Rho-type_GAP UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_chimaerin UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
NCBI Gene CHN1 ENTREZGENE
PANTHER CHIMERIN FAMILY MEMBER UniProtKB/TrEMBL
  N-CHIMAERIN UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PIRSF N-chimaerin UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A0D9RPX0 ENTREZGENE, UniProtKB/TrEMBL