ARHGAP15 (Rho GTPase activating protein 15)

Gene: ARHGAP15 (Rho GTPase activating protein 15) Chlorocebus sabaeus

Analyze

Symbol:

ARHGAP15

Name:

Rho GTPase activating protein 15

RGD ID:

18451512

Description:

ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of cell shape (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 1 (ortholog); genetic disease (ortholog); Mowat-Wilson syndrome (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

rho GTPase-activating protein 15

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	28,493,123 - 29,123,849 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	28,519,775 - 29,124,579 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	170,443,744 - 171,077,092 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 1 (ISO)

genetic disease (ISO)

Mowat-Wilson syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of cell shape (IEA,ISO)

signal transduction (IEA)

Cellular Component

cytoplasm (IEA)

membrane (IEA)

nucleoplasm (IEA)

plasma membrane (IEA)

Molecular Function

GTPase activator activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ARHGAP15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	28,493,123 - 29,123,849 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	28,519,775 - 29,124,579 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	170,443,744 - 171,077,092 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

ARHGAP15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	143,129,419 - 143,768,352 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	143,091,362 - 143,768,352 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	143,886,988 - 144,525,921 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	143,603,433 - 144,242,391 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	143,720,694 - 144,359,652	NCBI
Celera	2	137,599,271 - 138,238,118 (+)	NCBI		Celera
Cytogenetic Map	2	q22.2-q22.3	NCBI
HuRef	2	135,878,185 - 136,517,347 (+)	NCBI		HuRef
CHM1_1	2	143,891,883 - 144,531,020 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	143,577,714 - 144,216,567 (+)	NCBI		T2T-CHM13v2.0

Arhgap15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	43,638,786 - 44,285,965 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	43,638,836 - 44,285,965 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	43,748,798 - 44,395,953 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	43,748,824 - 44,395,953 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	43,604,344 - 44,243,143 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	43,570,836 - 44,209,632 (+)	NCBI		MGSCv36	mm8
Celera	2	45,470,136 - 46,103,622 (+)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	26.13	NCBI

Arhgap15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	48,382,945 - 49,002,213 (+)	NCBI		GRCr8
mRatBN7.2	3	27,989,368 - 28,592,722 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	27,989,633 - 28,600,265 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	31,386,432 - 31,990,702 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	39,971,464 - 40,575,746 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	37,790,180 - 38,394,454 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	28,626,987 - 29,236,225 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	28,627,084 - 29,236,219 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	33,831,379 - 34,442,272 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	24,256,620 - 24,389,618 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	24,152,991 - 24,765,169 (+)	NCBI
Celera	3	26,304,736 - 26,903,806 (+)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

Arhgap15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955440	9,590,685 - 10,189,937 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955440	9,591,173 - 10,182,086 (+)	NCBI	ChiLan1.0	ChiLan1.0

ARHGAP15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	31,134,907 - 31,774,416 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	31,149,867 - 31,789,384 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	16,067,081 - 16,706,372 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	147,218,310 - 147,855,697 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	147,217,528 - 147,855,517 (+)	Ensembl	panpan1.1		panPan2

ARHGAP15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	45,208,212 - 45,815,646 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	45,208,671 - 45,831,652 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	45,460,560 - 46,068,711 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	46,665,689 - 47,274,594 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	46,666,230 - 47,274,595 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	45,324,757 - 45,933,236 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	45,455,690 - 46,065,090 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	46,850,717 - 47,460,481 (+)	NCBI		UU_Cfam_GSD_1.0

Arhgap15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	108,063,480 - 108,665,504 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	32,951,231 - 33,528,407 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	33,203,456 - 33,554,167 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARHGAP15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	8,192,607 - 8,811,795 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	8,192,599 - 8,811,794 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	9,017,681 - 9,571,345 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Arhgap15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	42,865,128 - 43,481,731 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624732	42,865,010 - 43,482,670 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium		20
Low	36		60
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007964884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007964885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007964886	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000014299 ⟹ ENSCSAP00000012275

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	10	28,519,775 - 29,124,579 (+)	Ensembl

RefSeq Acc Id:

XM_007964884 ⟹ XP_007963075

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	10	28,493,123 - 29,123,849 (+)	NCBI
Vero_WHO_p1.0	NW_023666040	170,443,744 - 171,077,092 (-)	NCBI

Sequence:

show sequence

TCTTCCCCCAGTACTGAAATTAAGCAGCATCCAACACAGGCCTACTCTTACGACATGTGACTTT
ACTGTTTTCCGTTTTTGTTGAAAGAGTCATTAGCAGTTAGGAGTTGATGGCAGTTTCAATAACA
GGTCATTGCCGAGAAAAGGATAGCACTATAATATGCAGAAATCTACAAATTCTGATACTTCTTT
GGAAACACTGAATTCTACTCGCCAAGGCACAGGAGCTGTGCAAATGAGAATCAAAAATGCCAAC
AGCCACCATGACAGGCTCAGCCAAAGTAAATCCATGATCCTCACTGATGTTGGGAAGGTCACTG
AACCTATATCCCGACACAGAAGGAATCATTCACAGCATATCTTGAAAGATGTCATTCCTCCATT
GGAACAGTTGATGGTTGAAAAAGAAGGTTATCTGCAAAAAGCTAAAATTGCAGATGGAGGAAAG
AAACTAAGGAAAAACTGGTCTACTTCCTGGATTGTTCTTTCTAGTCGAAAAATTGAATTTTACA
AAGAATCCAAGCAACAGGCTCTGTCCAATATGAAAACTGGGCACAAACCAGAAAGTGTGGATTT
GTGTGGAGCACACATTGAATGGGCCAAGGAAAAATCGAGCAGAAAGAATGTCTTTCAGATCACA
ACAGTATCAGGAAATGAGTTCCTTCTACAGTCAGATATTGACTTCATCATATTGGATTGGTTCC
ACGCTATCAAAAATGCAATTGACAGATTGCCAAAGGATTCAAGTTGTCCATCAAGAAACCTGGA
ATTATTCAAAATCCAAAGATCCTCCAGCACTGAATTGCTAAGTCACTATGACAGTGATATAAAA
GAACAGAAACCAGAGCACAGAAAATCTTTAATGTTCAGACTGCATCATAGTGCTTCCGATACAA
GCGACAAAAATCGAGTTAAAAGCAGATTAAAGAAGTTTATTACCCGAAGACCTTCCCTGAAAAC
TCTGCAAGAAAAAGGACTTATTAAAGATCAAATTTTTGGCTCTCATCTGCACAAAGTGTGTGAA
CGTGAAAATTCCACAGTTCCGTGGTTTGTAAAGCAATGCATTGAAGCTGTTGAGAAAAGAGGTC
TAGATGTTGATGGAATATATCGAGTTAGTGGCAATCTGGCAACAATACAGAAGTTAAGATTTAT
TGTCAACCAAGAAGAGAAGCTGAATTTGGACGACAGCCAGTGGGAGGACATCCACGTTGTCACA
GGAGCACTGAAGATGTTTTTCCGGGAGCTGCCTGAGCCGCTCTTCCCTTACAGTTTCTTTGAGC
GGTTTGTGGAAGCGATCAAAAAGCAAGACAACACCGCAAGAATTGAAGCTGTAAAGTCTCTTGT
TCAAAAACTCCCTCCGCCAAATCGTGACACCATGAAAGTCCTCTTTGGACATCTAACTAAGATA
GTGGCCAAAGCCTCCAAGAACCTCATGTCCACACAAAGCTTAGGGATTGTATTTGGACCCACCC
TCCTGCGAGCTGAAAATGAAACAGGAAACATGGCGATCCACATGGTCTACCAGAACCAGATAGC
TGAGCTCATGCTGAGCGAGTACAGTAAGATCTTCAGCTCGGAGGAAGACTGACAGACAAGACAA
GCTACTGAATACGTTCACATCTGTCTTGATGCCTAATATTTTTACATTTCTGTAAACATATTTC
TGAAATATTTTTTGCCTTTCAAGCGACAGATGCCTCATTTTGTGAAAACTTAATGATGATTTTG
TGTTTAAGTTCCAAACATTTGAATAAAATAATTGACAATATTTGC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007963075	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000012275
	ENSCSAP00000012275.1

RefSeq Acc Id:	XP_007963075 ⟸ XM_007964884
- UniProtKB:	A0A0D9RUI6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000012275 ⟸ ENSCSAT00000014299

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000016210	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000014299.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.555.10	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
InterPro	PH-like_dom_sf	UniProtKB/TrEMBL
	PH_domain	UniProtKB/TrEMBL
	Rho_GTPase_activation_prot	UniProtKB/TrEMBL
	RhoGAP_dom	UniProtKB/TrEMBL
KEGG Report	csab:103217030	UniProtKB/TrEMBL
NCBI Gene	ARHGAP15	ENTREZGENE
PANTHER	RHO GTPASE-ACTIVATING PROTEIN 15	UniProtKB/TrEMBL
	RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN	UniProtKB/TrEMBL
Pfam	PF00169	UniProtKB/TrEMBL
	RhoGAP	UniProtKB/TrEMBL
PROSITE	PH_DOMAIN	UniProtKB/TrEMBL
	RHOGAP	UniProtKB/TrEMBL
SMART	RhoGAP	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	SSF48350	UniProtKB/TrEMBL
UniProt	A0A0D9RUI6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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