TBC1D15 (TBC1 domain family member 15) - Rat Genome Database

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Gene: TBC1D15 (TBC1 domain family member 15) Chlorocebus sabaeus
Analyze
Symbol: TBC1D15
Name: TBC1 domain family member 15
RGD ID: 18531099
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of cilium assembly (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11167,472,771 - 67,554,329 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1167,473,030 - 67,556,694 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037178,098,752 - 178,180,097 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TBC1D15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11167,472,771 - 67,554,329 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1167,473,030 - 67,556,694 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037178,098,752 - 178,180,097 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TBC1D15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381271,839,759 - 71,924,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1271,839,707 - 71,927,248 (+)EnsemblGRCh38hg38GRCh38
GRCh371272,233,539 - 72,318,093 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361270,519,806 - 70,604,364 (+)NCBINCBI36Build 36hg18NCBI36
Build 341270,519,805 - 70,604,362NCBI
Celera1271,896,776 - 71,983,914 (+)NCBICelera
Cytogenetic Map12q21.1NCBI
HuRef1269,283,328 - 69,370,238 (+)NCBIHuRef
CHM1_11272,200,619 - 72,287,783 (+)NCBICHM1_1
T2T-CHM13v2.01271,817,237 - 71,901,791 (+)NCBIT2T-CHM13v2.0
Tbc1d15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910115,031,459 - 115,087,343 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10115,033,777 - 115,087,372 (-)EnsemblGRCm39 Ensembl
GRCm3810115,197,871 - 115,251,493 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10115,197,872 - 115,251,467 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710114,634,927 - 114,688,549 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610114,602,568 - 114,655,575 (-)NCBIMGSCv36mm8
Celera10117,126,897 - 117,180,707 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1063.51NCBI
Tbc1d15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8752,690,770 - 52,746,309 (-)NCBIGRCr8
mRatBN7.2750,804,553 - 50,860,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl750,804,012 - 50,860,175 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0758,164,190 - 58,219,804 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl758,164,198 - 58,219,790 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0758,173,077 - 58,228,703 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4754,445,319 - 54,504,473 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1754,466,468 - 54,525,075 (-)NCBI
Celera747,597,371 - 47,652,320 (-)NCBICelera
Cytogenetic Map7q22NCBI
Tbc1d15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540511,821,272 - 11,876,133 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540511,821,601 - 11,876,133 (+)NCBIChiLan1.0ChiLan1.0
TBC1D15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21079,867,684 - 79,952,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11279,864,087 - 79,950,264 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01269,362,187 - 69,446,794 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11272,220,590 - 72,304,715 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1272,220,582 - 72,304,715 (+)Ensemblpanpan1.1panPan2
TBC1D15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11013,357,511 - 13,426,293 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1013,357,620 - 13,425,285 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1013,296,627 - 13,365,113 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01013,494,056 - 13,562,336 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1013,494,147 - 13,562,622 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11013,355,597 - 13,423,800 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01013,604,190 - 13,672,615 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01013,727,852 - 13,796,539 (+)NCBIUU_Cfam_GSD_1.0
Tbc1d15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494544,764,790 - 44,833,671 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936568894,627 - 963,545 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936568894,674 - 963,530 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl535,827,473 - 35,908,385 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1535,827,385 - 35,907,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2538,528,912 - 38,608,802 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tbc1d15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475025,812,645 - 25,878,578 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 36
Low 20 24
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000002106   ⟹   ENSCSAP00000000435
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1167,473,030 - 67,556,694 (+)Ensembl
RefSeq Acc Id: XM_008004036   ⟹   XP_008002227
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11167,473,050 - 67,554,329 (+)NCBI
Vero_WHO_p1.0NW_023666037178,098,752 - 178,180,097 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008004039   ⟹   XP_008002230
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11167,473,050 - 67,554,329 (+)NCBI
Vero_WHO_p1.0NW_023666037178,098,754 - 178,180,096 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037996810   ⟹   XP_037852738
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037178,098,754 - 178,180,097 (-)NCBI
RefSeq Acc Id: XM_037996811   ⟹   XP_037852739
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037178,098,754 - 178,180,097 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008002227 (Get FASTA)   NCBI Sequence Viewer  
  XP_008002230 (Get FASTA)   NCBI Sequence Viewer  
  XP_037852738 (Get FASTA)   NCBI Sequence Viewer  
  XP_037852739 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000435.1
Reference Protein Sequences
RefSeq Acc Id: XP_008002227   ⟸   XM_008004036
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QVP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002230   ⟸   XM_008004039
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000435   ⟸   ENSCSAT00000002106
RefSeq Acc Id: XP_037852739   ⟸   XM_037996811
- Peptide Label: isoform X4
- UniProtKB: A0A0D9QVP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037852738   ⟸   XM_037996810
- Peptide Label: isoform X3
- UniProtKB: A0A0D9QVP6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004078 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002106.1 UniProtKB/TrEMBL
Gene3D-CATH putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  SGSM1/2_RBD UniProtKB/TrEMBL
NCBI Gene TBC1D15 ENTREZGENE
PANTHER TBC1 DOMAIN FAMILY MEMBER 15 UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
Pfam PH_RBD UniProtKB/TrEMBL
  RabGAP-TBC UniProtKB/TrEMBL
PROSITE TBC_RABGAP UniProtKB/TrEMBL
SMART TBC UniProtKB/TrEMBL
Superfamily-SCOP SSF47923 UniProtKB/TrEMBL
UniProt A0A0D9QVP6 ENTREZGENE, UniProtKB/TrEMBL