RASAL3 (RAS protein activator like 3) - Rat Genome Database

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Gene: RASAL3 (RAS protein activator like 3) Chlorocebus sabaeus
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Symbol: RASAL3
Name: RAS protein activator like 3
RGD ID: 18454099
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN negative regulation of Ras protein signal transduction (ortholog); positive regulation of NK T cell proliferation (ortholog); ASSOCIATED WITH acute megakaryocytic leukemia (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RAS protein activator like-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1614,054,517 - 14,068,423 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl614,054,522 - 14,064,590 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,439,480 - 5,453,339 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RASAL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1614,054,517 - 14,068,423 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl614,054,522 - 14,064,590 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,439,480 - 5,453,339 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RASAL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,451,624 - 15,464,544 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,451,624 - 15,464,544 (-)EnsemblGRCh38hg38GRCh38
GRCh371915,562,435 - 15,575,355 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,423,438 - 15,436,382 (-)NCBINCBI36Build 36hg18NCBI36
Celera1915,459,253 - 15,472,196 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1915,130,271 - 15,143,115 (-)NCBIHuRef
CHM1_11915,562,083 - 15,575,024 (-)NCBICHM1_1
T2T-CHM13v2.01915,576,612 - 15,589,556 (-)NCBIT2T-CHM13v2.0
Rasal3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391732,609,633 - 32,622,586 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1732,609,633 - 32,622,557 (-)EnsemblGRCm39 Ensembl
GRCm381732,390,659 - 32,403,582 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1732,390,659 - 32,403,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv371732,527,606 - 32,540,526 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361732,121,906 - 32,136,226 (-)NCBIMGSCv36mm8
Celera1733,304,546 - 33,317,468 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.55NCBI
Rasal3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8712,047,090 - 12,061,883 (-)NCBIGRCr8
mRatBN7.2711,396,554 - 11,411,347 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl711,396,090 - 11,411,465 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx714,214,565 - 14,229,763 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0716,091,987 - 16,107,185 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,963,524 - 13,978,783 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0714,403,592 - 14,419,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl714,403,592 - 14,418,950 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,557,751 - 14,573,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,953,506 - 12,968,785 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,953,969 - 13,036,520 (-)NCBI
Celera79,507,312 - 9,522,488 (-)NCBICelera
Cytogenetic Map7q11NCBI
Rasal3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,795,842 - 7,808,511 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554957,795,619 - 7,808,674 (+)NCBIChiLan1.0ChiLan1.0
RASAL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22020,364,784 - 20,377,718 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11919,367,558 - 19,380,483 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,982,964 - 14,995,889 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,969,412 - 15,981,800 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,969,582 - 15,981,800 (-)Ensemblpanpan1.1panPan2
RASAL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12046,733,072 - 46,743,657 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2046,732,952 - 46,743,924 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,580,801 - 46,591,492 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,219,876 - 47,230,567 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,218,828 - 47,230,702 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,454,750 - 46,465,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02046,871,406 - 46,882,096 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,144,900 - 47,155,591 (+)NCBIUU_Cfam_GSD_1.0
Rasal3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,497,560 - 205,504,782 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365965,048,068 - 5,059,074 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASAL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,142,769 - 62,153,799 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,142,368 - 62,153,812 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2261,716,444 - 61,725,472 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rasal3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,538,550 - 2,550,327 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,538,131 - 2,550,540 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000004115   ⟹   ENSCSAP00000002378
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl614,054,522 - 14,064,590 (-)Ensembl
RefSeq Acc Id: XM_007995593   ⟹   XP_007993784
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1614,054,731 - 14,068,231 (-)NCBI
Vero_WHO_p1.0NW_0236660745,439,480 - 5,453,339 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007995594   ⟹   XP_007993785
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1614,054,517 - 14,068,423 (-)NCBI
Vero_WHO_p1.0NW_0236660745,439,483 - 5,453,339 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007993784 (Get FASTA)   NCBI Sequence Viewer  
  XP_007993785 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000002378
  ENSCSAP00000002378.1
RefSeq Acc Id: XP_007993785   ⟸   XM_007995594
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R189 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007993784   ⟸   XM_007995593
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R189 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000002378   ⟸   ENSCSAT00000004115


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006077 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004115.1 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/TrEMBL
  RasGAP_dom UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
NCBI Gene RASAL3 ENTREZGENE
PANTHER PTHR10194 UniProtKB/TrEMBL
  RAS PROTEIN ACTIVATOR LIKE-3 UniProtKB/TrEMBL
Pfam RasGAP UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/TrEMBL
SMART RasGAP UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
UniProt A0A0D9R189 ENTREZGENE, UniProtKB/TrEMBL