TBC1D17 (TBC1 domain family member 17) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TBC1D17 (TBC1 domain family member 17) Chlorocebus sabaeus
Analyze
Symbol: TBC1D17
Name: TBC1 domain family member 17
RGD ID: 18548717
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of cilium assembly (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,034,986 - 43,045,462 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl643,035,280 - 43,045,646 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607323,010,377 - 23,020,752 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TBC1D17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,034,986 - 43,045,462 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl643,035,280 - 43,045,646 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607323,010,377 - 23,020,752 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TBC1D17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,877,702 - 49,888,750 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,877,666 - 49,888,750 (+)EnsemblGRCh38hg38GRCh38
GRCh371950,380,959 - 50,392,007 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,072,641 - 55,083,813 (+)NCBINCBI36Build 36hg18NCBI36
Build 341955,072,640 - 55,083,812NCBI
Celera1947,250,191 - 47,261,510 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,757,018 - 46,768,344 (+)NCBIHuRef
CHM1_11950,382,518 - 50,393,843 (+)NCBICHM1_1
T2T-CHM13v2.01952,877,839 - 52,888,886 (+)NCBIT2T-CHM13v2.0
Tbc1d17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,490,200 - 44,498,314 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,484,047 - 44,498,503 (-)EnsemblGRCm39 Ensembl
GRCm38744,840,776 - 44,849,079 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,834,623 - 44,849,079 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,096,146 - 52,104,449 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,709,074 - 44,717,121 (-)NCBIMGSCv36mm8
Celera740,290,969 - 40,299,272 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.93NCBI
Tbc1d17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,461,266 - 104,469,615 (-)NCBIGRCr8
mRatBN7.2195,324,770 - 95,333,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,322,737 - 95,333,005 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,710,162 - 100,718,385 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,182,827 - 109,191,050 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,473,235 - 102,481,458 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01100,836,993 - 100,845,216 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,836,990 - 100,845,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,901,663 - 101,909,886 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,313,421 - 95,321,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,391,411 - 95,399,943 (-)NCBI
Celera189,586,510 - 89,594,733 (-)NCBICelera
Cytogenetic Map1q22NCBI
Tbc1d17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,045,988 - 1,055,891 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,047,389 - 1,055,891 (-)NCBIChiLan1.0ChiLan1.0
TBC1D17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,992,296 - 56,004,317 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,914,019 - 57,925,163 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,890,557 - 46,901,761 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,806,294 - 55,819,012 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,806,294 - 55,820,195 (+)Ensemblpanpan1.1panPan2
TBC1D17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,673,716 - 106,686,386 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,674,097 - 106,686,003 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,257,164 - 106,269,894 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,195,162 - 107,207,891 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,195,162 - 107,207,478 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11106,867,267 - 106,879,990 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,509,455 - 106,521,986 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,349,728 - 107,362,450 (-)NCBIUU_Cfam_GSD_1.0
Tbc1d17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,046,287 - 22,056,704 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,664,708 - 3,674,459 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,664,423 - 3,674,890 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,890,019 - 54,906,144 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,890,002 - 54,906,144 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,620,282 - 50,635,288 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tbc1d17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,444,682 - 4,453,964 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,444,940 - 4,454,153 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 2 50
Low 18 10
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000000434   ⟹   ENSCSAP00000015625
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl643,035,280 - 43,045,646 (+)Ensembl
RefSeq Acc Id: XM_007997611   ⟹   XP_007995802
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1643,034,986 - 43,045,462 (+)NCBI
Vero_WHO_p1.0NW_02366607323,010,377 - 23,020,752 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005238361
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607323,010,377 - 23,020,752 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007995802 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015625
  ENSCSAP00000015625.1
Reference Protein Sequences
RefSeq Acc Id: XP_007995802   ⟸   XM_007997611
- UniProtKB: A0A0D9S436 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015625   ⟸   ENSCSAT00000000434


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002417 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000434.1 UniProtKB/TrEMBL
Gene3D-CATH putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  SGSM1/2_RBD UniProtKB/TrEMBL
KEGG Report csab:103235061 UniProtKB/TrEMBL
NCBI Gene TBC1D17 ENTREZGENE
PANTHER TBC1 DOMAIN FAMILY MEMBER 17 UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
Pfam PH_RBD UniProtKB/TrEMBL
  RabGAP-TBC UniProtKB/TrEMBL
PROSITE TBC_RABGAP UniProtKB/TrEMBL
SMART TBC UniProtKB/TrEMBL
Superfamily-SCOP SSF47923 UniProtKB/TrEMBL
UniProt A0A0D9S436 ENTREZGENE, UniProtKB/TrEMBL