WDR48 (WD repeat domain 48) - Rat Genome Database

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Gene: WDR48 (WD repeat domain 48) Chlorocebus sabaeus
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Symbol: WDR48
Name: WD repeat domain 48
RGD ID: 18759590
Description: ENCODES a protein that exhibits deubiquitinase activator activity (ortholog); DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN DNA damage response (ortholog); double-strand break repair via homologous recombination (ortholog); embryonic organ development (ortholog); ASSOCIATED WITH cognitive disorder (ortholog); genetic disease (ortholog); hereditary spastic paraplegia (ortholog); FOUND IN cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WD repeat-containing protein 48
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115319,589 - 366,265 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl15319,810 - 366,246 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660639,046,714 - 9,093,695 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
WDR48
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115319,589 - 366,265 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl15319,810 - 366,246 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660639,046,714 - 9,093,695 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
WDR48
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38339,052,016 - 39,096,664 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl339,052,013 - 39,096,671 (+)EnsemblGRCh38hg38GRCh38
GRCh37339,093,507 - 39,138,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36339,068,511 - 39,112,886 (+)NCBINCBI36Build 36hg18NCBI36
Build 34339,068,510 - 39,112,883NCBI
Celera339,033,745 - 39,078,385 (+)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef339,135,626 - 39,179,803 (+)NCBIHuRef
CHM1_1339,044,573 - 39,088,966 (+)NCBICHM1_1
T2T-CHM13v2.0339,064,178 - 39,108,828 (+)NCBIT2T-CHM13v2.0
Wdr48
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,723,961 - 119,755,652 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9119,723,944 - 119,755,653 (+)EnsemblGRCm39 Ensembl
GRCm389119,894,895 - 119,926,586 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,894,878 - 119,926,587 (+)EnsemblGRCm38mm10GRCm38
MGSCv379119,804,013 - 119,835,697 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369119,743,593 - 119,775,277 (+)NCBIMGSCv36mm8
Celera9120,362,077 - 120,393,799 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map971.33NCBI
Wdr48
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88128,499,721 - 128,532,930 (+)NCBIGRCr8
mRatBN7.28119,622,053 - 119,655,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,622,048 - 119,655,264 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8125,203,504 - 125,236,737 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08123,402,547 - 123,435,784 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08121,235,273 - 121,268,518 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08128,577,080 - 128,610,287 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,577,080 - 128,610,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,778,763 - 127,811,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,850,235 - 124,883,442 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18124,869,881 - 124,902,301 (+)NCBI
Celera8118,769,024 - 118,802,212 (+)NCBICelera
Cytogenetic Map8q32NCBI
Wdr48
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542724,873,616 - 24,917,691 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542724,873,616 - 24,917,691 (-)NCBIChiLan1.0ChiLan1.0
WDR48
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2239,003,822 - 39,048,256 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1339,008,501 - 39,053,018 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0338,948,440 - 38,992,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1339,228,920 - 39,273,300 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl339,228,920 - 39,273,300 (+)Ensemblpanpan1.1panPan2
WDR48
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1238,716,598 - 8,766,242 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl238,715,700 - 8,764,678 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha238,756,451 - 8,805,903 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0239,005,151 - 9,054,838 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl239,004,578 - 9,054,838 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1238,818,871 - 8,868,534 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0238,961,107 - 9,010,791 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0238,954,513 - 9,004,213 (+)NCBIUU_Cfam_GSD_1.0
Wdr48
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118195,169,311 - 195,213,154 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647328,307,875 - 28,354,279 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647328,307,913 - 28,351,727 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR48
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1323,735,567 - 23,786,308 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11323,735,566 - 23,786,312 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,995,433 - 26,045,850 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Wdr48
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247311,884,666 - 1,934,754 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247311,884,660 - 1,934,818 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 9 60
Low 11
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000012782   ⟹   ENSCSAP00000010805
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl15319,810 - 366,246 (-)Ensembl
RefSeq Acc Id: XM_007971728   ⟹   XP_007969919
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.115319,589 - 366,265 (-)NCBI
Vero_WHO_p1.0NW_0236660639,046,714 - 9,093,695 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037988435   ⟹   XP_037844363
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660639,046,714 - 9,093,695 (-)NCBI
RefSeq Acc Id: XM_037988436   ⟹   XP_037844364
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660639,046,714 - 9,093,413 (-)NCBI
RefSeq Acc Id: XM_037988437   ⟹   XP_037844365
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660639,046,714 - 9,093,413 (-)NCBI
RefSeq Acc Id: XM_037988438   ⟹   XP_037844366
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660639,046,714 - 9,093,695 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007969919 (Get FASTA)   NCBI Sequence Viewer  
  XP_037844363 (Get FASTA)   NCBI Sequence Viewer  
  XP_037844364 (Get FASTA)   NCBI Sequence Viewer  
  XP_037844365 (Get FASTA)   NCBI Sequence Viewer  
  XP_037844366 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010805.1
RefSeq Acc Id: XP_007969919   ⟸   XM_007971728
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000010805   ⟸   ENSCSAT00000012782
RefSeq Acc Id: XP_037844363   ⟸   XM_037988435
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037844366   ⟸   XM_037988438
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037844365   ⟸   XM_037988437
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037844364   ⟸   XM_037988436
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014688 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012782.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  WDR48/Bun107 UniProtKB/TrEMBL
KEGG Report csab:103221048 UniProtKB/TrEMBL
NCBI Gene WDR48 ENTREZGENE
PANTHER WD REPEAT-CONTAINING PROTEIN 48 UniProtKB/TrEMBL
  WD REPEAT-CONTAINING PROTEIN 48 UniProtKB/TrEMBL
Pfam DUF3337 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9RQB6_CHLSB UniProtKB/TrEMBL