actinomycin D - Ontology Report - Rat Genome Database

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Term:	actinomycin D	go back to main search page
Accession:	CHEBI:27666	browse the term
Definition:	An actinomycin that has formula C62H86N12O16.
Synonyms:	exact_synonym:	2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide
	related_synonym:	2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide; ActD; C62H86N12O16; Dactinomycin; InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1; InChIKey=RJURFGZVJUQBHK-IIXSONLDSA-N; [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C; actinomycin C1; actinomycin IV
	alt_id:	CHEBI:22218; CHEBI:2446
	xref_casrn:	50-76-0
	xref:	Beilstein:4173766 "Beilstein Registry Number"; ChEMBL:542943 "ChEMBL COMPOUND"; ChemIDplus:50-76-0 "CAS Registry Number"; DrugBank:DB00970 "DrugBank"; KEGG COMPOUND:50-76-0 "CAS Registry Number"; KEGG COMPOUND:C06770 "KEGG COMPOUND"
	xref_mesh:	MESH:D003609
	xref:	Wikipedia:Dactinomycin "Wikipedia"

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actinomycin D
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1		decreases response to substance	ISO	7	87,133,179	87,342,639	RGD:6480464	CTD
G	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1		decreases response to substance	EXP	7	87,133,179	87,342,639	RGD:6480464	CTD
G	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1		multiple interactions	EXP	7	87,133,179	87,342,639	RGD:6480464	CTD
G	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1		decreases response to substance	EXP	16	16,043,434	16,236,931	RGD:6480464	CTD
G	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1		decreases response to substance	ISO	16	16,043,434	16,236,931	RGD:6480464	CTD
G	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2		decreases response to substance	ISO	10	101,542,463	101,611,662	RGD:6480464	CTD
G	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2		multiple interactions	ISO	10	101,542,463	101,611,662	RGD:6480464	CTD
G	ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2		multiple interactions	EXP	4	89,011,416	89,152,474	RGD:6480464	CTD
G	ABHD3	abhydrolase domain containing 3		increases expression	EXP	18	19,230,858	19,284,766	RGD:6480464	CTD
G	ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))		multiple interactions	ISO	7	150,549,573	150,558,379	RGD:6480464	CTD
G	ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))		multiple interactions	ISO	7	150,549,573	150,558,379	RGD:6480464	CTD
G	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1		multiple interactions	ISO	17	61,554,422	61,575,741	RGD:6480464	CTD
G	ACSL6	acyl-CoA synthetase long-chain family member 6		multiple interactions	ISO	5	131,285,666	131,347,761	RGD:6480464	CTD
G	ADAM9	ADAM metallopeptidase domain 9		multiple interactions	EXP	8	38,854,505	38,962,780	RGD:6480464	CTD
G	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)		multiple interactions	EXP	1	230,838,269	230,850,336	RGD:6480464	CTD
G	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)		multiple interactions	EXP	1	230,838,269	230,850,336	RGD:6480464	CTD
G	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)		multiple interactions	ISO	1	230,838,269	230,850,336	RGD:6480464	CTD
G	AHR	aryl hydrocarbon receptor		multiple interactions	EXP	7	17,338,276	17,385,775	RGD:6480464	CTD
G	AHR	aryl hydrocarbon receptor		multiple interactions	ISO	7	17,338,276	17,385,775	RGD:6480464	CTD
G	AICDA	activation-induced cytidine deaminase		multiple interactions	ISO	12	8,754,762	8,765,442	RGD:6480464	CTD
G	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1		multiple interactions	EXP	X	129,263,337	129,299,861	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	ISO	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	ALPI	alkaline phosphatase, intestinal		multiple interactions	ISO	2	233,320,833	233,324,742	RGD:6480464	CTD
G	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta		increases expression	EXP	12	15,094,950	15,114,562	RGD:6480464	CTD
G	ARNT	aryl hydrocarbon receptor nuclear translocator		multiple interactions	ISO	1	150,782,181	150,849,244	RGD:6480464	CTD
G	ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)		multiple interactions	EXP	22	39,916,569	39,918,691	RGD:6480464	CTD
G	AVP	arginine vasopressin		multiple interactions	ISO	20	3,063,202	3,065,370	RGD:6480464	CTD
G	AXL	AXL receptor tyrosine kinase		increases expression	EXP	19	41,725,108	41,767,671	RGD:6480464	CTD
G	BAG3	BCL2-associated athanogene 3		multiple interactions	EXP	10	121,410,882	121,437,331	RGD:6480464	CTD
G	BAK1	BCL2-antagonist/killer 1		multiple interactions	ISO	6	33,540,323	33,548,070	RGD:6480464	CTD
G	BAX	BCL2-associated X protein		increases expression	EXP	19	49,458,117	49,465,055	RGD:6480464	CTD
G	BAX	BCL2-associated X protein		increases expression	EXP	19	49,458,117	49,465,055	RGD:6480464	CTD
G	BAX	BCL2-associated X protein		multiple interactions	EXP	19	49,458,117	49,465,055	RGD:6480464	CTD
G	BAX	BCL2-associated X protein		increases expression	EXP	19	49,458,117	49,465,055	RGD:6480464	CTD
G	BAX	BCL2-associated X protein		multiple interactions	ISO	19	49,458,117	49,465,055	RGD:6480464	CTD
G	BBC3	BCL2 binding component 3		increases expression	EXP	19	47,724,079	47,736,023	RGD:6480464	CTD
G	BCL2	B-cell CLL/lymphoma 2		multiple interactions	EXP	18	60,790,579	60,986,613	RGD:6480464	CTD
G	BCL2	B-cell CLL/lymphoma 2		multiple interactions	EXP	18	60,790,579	60,986,613	RGD:6480464	CTD
G	BCL2	B-cell CLL/lymphoma 2		decreases expression	EXP	18	60,790,579	60,986,613	RGD:6480464	CTD
G	BCL2	B-cell CLL/lymphoma 2		decreases expression	EXP	18	60,790,579	60,986,613	RGD:6480464	CTD
G	BCL2	B-cell CLL/lymphoma 2		multiple interactions	EXP	18	60,790,579	60,986,613	RGD:6480464	CTD
G	BCL2	B-cell CLL/lymphoma 2		multiple interactions	EXP	18	60,790,579	60,986,613	RGD:6480464	CTD
G	BCL2A1	BCL2-related protein A1		multiple interactions	EXP	15	80,253,232	80,263,643	RGD:6480464	CTD
G	BCL2L1	BCL2-like 1		decreases expression	EXP	20	30,252,261	30,310,656	RGD:6480464	CTD
G	BCL2L1	BCL2-like 1		increases expression	EXP	20	30,252,261	30,310,656	RGD:6480464	CTD
G	BCL2L1	BCL2-like 1		increases expression	EXP	20	30,252,261	30,310,656	RGD:6480464	CTD
G	BCL2L1	BCL2-like 1		multiple interactions	EXP	20	30,252,261	30,310,656	RGD:6480464	CTD
G	BCL2L11	BCL2-like 11 (apoptosis facilitator)		multiple interactions	ISO	2	111,878,491	111,926,022	RGD:6480464	CTD
G	BID	BH3 interacting domain death agonist		multiple interactions	EXP	22	18,216,906	18,257,431	RGD:6480464	CTD
G	BID	BH3 interacting domain death agonist		multiple interactions	ISO	22	18,216,906	18,257,431	RGD:6480464	CTD
G	BIRC3	baculoviral IAP repeat containing 3		multiple interactions	EXP	11	102,188,181	102,210,134	RGD:6480464	CTD
G	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3		multiple interactions	ISO	10	133,781,204	133,795,435	RGD:6480464	CTD
G	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3		multiple interactions	ISO	10	133,781,204	133,795,435	RGD:6480464	CTD
G	BSDC1	BSD domain containing 1		increases expression	EXP	1	32,830,704	32,860,062	RGD:6480464	CTD
G	CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit		multiple interactions	ISO	17	48,638,429	48,704,835	RGD:6480464	CTD
G	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit		multiple interactions	ISO	16	1,203,241	1,271,772	RGD:6480464	CTD
G	CASP2	caspase 2, apoptosis-related cysteine peptidase		increases cleavage	EXP	7	142,985,308	143,004,789	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		multiple interactions	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		decreases expression	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		increases activity	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		multiple interactions	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP7	caspase 7, apoptosis-related cysteine peptidase		multiple interactions	EXP	10	115,438,921	115,490,668	RGD:6480464	CTD
G	CASP7	caspase 7, apoptosis-related cysteine peptidase		multiple interactions	EXP	10	115,438,921	115,490,668	RGD:6480464	CTD
G	CASP7	caspase 7, apoptosis-related cysteine peptidase		decreases expression	EXP	10	115,438,921	115,490,668	RGD:6480464	CTD
G	CASP7	caspase 7, apoptosis-related cysteine peptidase		multiple interactions	EXP	10	115,438,921	115,490,668	RGD:6480464	CTD
G	CASP8	caspase 8, apoptosis-related cysteine peptidase		decreases expression	EXP	2	202,098,166	202,152,434	RGD:6480464	CTD
G	CASP9	caspase 9, apoptosis-related cysteine peptidase		multiple interactions	EXP	1	15,818,769	15,851,285	RGD:6480464	CTD
G	CAV1	caveolin 1, caveolae protein, 22kDa		multiple interactions	EXP	7	116,164,839	116,201,239	RGD:6480464	CTD
G	CCL11	chemokine (C-C motif) ligand 11		multiple interactions	EXP	17	32,612,687	32,615,199	RGD:6480464	CTD
G	CCL2	chemokine (C-C motif) ligand 2		multiple interactions	EXP	17	32,582,296	32,584,222	RGD:6480464	CTD
G	CCL2	chemokine (C-C motif) ligand 2		multiple interactions	EXP	17	32,582,296	32,584,222	RGD:6480464	CTD
G	CCND1	cyclin D1		decreases stability	ISO	11	69,455,873	69,469,242	RGD:6480464	CTD
G	CD1D	CD1d molecule		multiple interactions	EXP	1	158,149,737	158,156,217	RGD:6480464	CTD
G	CD28	CD28 molecule		multiple interactions	EXP	2	204,571,198	204,603,635	RGD:6480464	CTD
G	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)		multiple interactions	EXP	6	36,644,237	36,655,116	RGD:6480464	CTD
G	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)		decreases expression	EXP	6	36,644,237	36,655,116	RGD:6480464	CTD
G	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta		decreases expression	EXP	20	48,807,120	48,809,227	RGD:6480464	CTD
G	CEL	carboxyl ester lipase		increases expression	EXP	9	135,937,365	135,947,248	RGD:6480464	CTD
G	CFLAR	CASP8 and FADD-like apoptosis regulator		decreases expression	EXP	2	201,980,877	202,037,411	RGD:6480464	CTD
G	CFLAR	CASP8 and FADD-like apoptosis regulator		decreases expression	EXP	2	201,980,877	202,037,411	RGD:6480464	CTD
G	CKB	creatine kinase, brain		multiple interactions	ISO	14	103,985,995	103,989,196	RGD:6480464	CTD
G	CLMN	calmin (calponin-like, transmembrane)		multiple interactions	EXP	14	95,648,276	95,786,245	RGD:6480464	CTD
G	CNR1	cannabinoid receptor 1 (brain)		multiple interactions	EXP	6	88,849,583	88,875,767	RGD:6480464	CTD
G	CNR2	cannabinoid receptor 2 (macrophage)		multiple interactions	EXP	1	24,200,460	24,239,817	RGD:6480464	CTD
G	COL1A1	collagen, type I, alpha 1		multiple interactions	EXP	17	48,261,457	48,279,000	RGD:6480464	CTD
G	COL1A2	collagen, type I, alpha 2		multiple interactions	ISO	7	94,023,873	94,060,544	RGD:6480464	CTD
G	CRABP2	cellular retinoic acid binding protein 2		increases expression	EXP	1	156,669,398	156,675,608	RGD:6480464	CTD
G	CSF2	colony stimulating factor 2 (granulocyte-macrophage)		multiple interactions	ISO	5	131,409,485	131,411,863	RGD:6480464	CTD
G	CSF2	colony stimulating factor 2 (granulocyte-macrophage)		multiple interactions	EXP	5	131,409,485	131,411,863	RGD:6480464	CTD
G	CYCS	cytochrome c, somatic		multiple interactions	ISO	7	25,158,270	25,164,980	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	EXP	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	EXP	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	EXP	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	ISO	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	ISO	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	ISO	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	ISO	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	ISO	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	ISO	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	EXP	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	EXP	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	EXP	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	ISO	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1		multiple interactions	EXP	15	75,011,883	75,017,877	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1		multiple interactions	EXP	2	38,294,746	38,303,323	RGD:6480464	CTD
G	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1		multiple interactions	ISO	2	38,294,746	38,303,323	RGD:6480464	CTD
G	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1		decreases expression	ISO	2	38,294,746	38,303,323	RGD:6480464	CTD
G	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1		multiple interactions	ISO	2	38,294,746	38,303,323	RGD:6480464	CTD
G	CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1		multiple interactions	EXP	19	41,620,353	41,634,281	RGD:6480464	CTD
G	CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1		multiple interactions	ISO	19	41,699,115	41,713,444	RGD:6480464	CTD
G	CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4		multiple interactions	ISO	7	99,354,583	99,381,811	RGD:6480464	CTD
G	CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4		multiple interactions	EXP	7	99,354,583	99,381,811	RGD:6480464	CTD
G	DDAH2	dimethylarginine dimethylaminohydrolase 2		multiple interactions	EXP	6	31,694,817	31,698,039	RGD:6480464	CTD
G	DIO3	deiodinase, iodothyronine, type III		multiple interactions	ISO	14	102,027,688	102,029,789	RGD:6480464	CTD
G	DPYSL4	dihydropyrimidinase-like 4		increases expression	EXP	10	134,000,414	134,019,280	RGD:6480464	CTD
G	DSCR6	Down syndrome critical region gene 6		increases expression	EXP	21	38,378,863	38,391,959	RGD:6480464	CTD
G	EDNRA	endothelin receptor type A		multiple interactions	ISO	4	148,402,069	148,466,106	RGD:6480464	CTD
G	EDNRB	endothelin receptor type B		multiple interactions	ISO	13 13	78,469,616 78,513,393	78,549,664 78,549,674	RGD:6480464	CTD
G	EDNRB	endothelin receptor type B		multiple interactions	ISO	13 13	78,469,616 78,513,393	78,549,664 78,549,674	RGD:6480464	CTD
G	EDNRB	endothelin receptor type B		multiple interactions	ISO	13 13	78,469,616 78,513,393	78,549,664 78,549,674	RGD:6480464	CTD
G	EFNB2	ephrin-B2		multiple interactions	EXP	13	107,142,079	107,187,388	RGD:6480464	CTD
G	EGF	epidermal growth factor		multiple interactions	ISO	4	110,834,040	110,934,118	RGD:6480464	CTD
G	EGFR	epidermal growth factor receptor		multiple interactions	ISO	7	55,086,725	55,275,031	RGD:6480464	CTD
G	EGR1	early growth response 1		multiple interactions	ISO	5	137,801,181	137,805,004	RGD:6480464	CTD
G	ELOVL3	ELOVL fatty acid elongase 3		multiple interactions	ISO	10	103,986,143	103,989,346	RGD:6480464	CTD
G	EMP1	epithelial membrane protein 1		increases expression	EXP	12	13,349,602	13,369,708	RGD:6480464	CTD
G	EMP3	epithelial membrane protein 3		increases expression	EXP	19	48,828,629	48,833,810	RGD:6480464	CTD
G	FADD	Fas (TNFRSF6)-associated via death domain		decreases expression	EXP	11	70,049,269	70,053,508	RGD:6480464	CTD
G	FADS3	fatty acid desaturase 3		increases expression	EXP	11	61,640,998	61,659,006	RGD:6480464	CTD
G	FBL	fibrillarin		affects localization	EXP	19	40,325,093	40,337,054	RGD:6480464	CTD
G	FCAR	Fc fragment of IgA, receptor for		multiple interactions	EXP	19	55,385,549	55,401,839	RGD:6480464	CTD
G	FGFR1	fibroblast growth factor receptor 1		multiple interactions	ISO	8	38,268,656	38,326,352	RGD:6480464	CTD
G	FHL1	four and a half LIM domains 1		multiple interactions	ISO	X	135,228,861	135,293,518	RGD:6480464	CTD
G	FLNC	filamin C, gamma		increases expression	EXP	7	128,470,483	128,499,328	RGD:6480464	CTD
G	FN1	fibronectin 1		multiple interactions	EXP	2	216,225,177	216,300,791	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		multiple interactions	ISO	14	75,745,481	75,748,937	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		multiple interactions	ISO	14	75,745,481	75,748,937	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		multiple interactions	ISO	14	75,745,481	75,748,937	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		multiple interactions	ISO	14	75,745,481	75,748,937	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		decreases expression	ISO	14	75,745,481	75,748,937	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		multiple interactions	EXP	14	75,745,481	75,748,937	RGD:6480464	CTD
G	G6PD	glucose-6-phosphate dehydrogenase		multiple interactions	ISO	X	153,759,606	153,775,787	RGD:6480464	CTD
G	GADD45A	growth arrest and DNA-damage-inducible, alpha		multiple interactions	EXP	1	68,150,860	68,154,021	RGD:6480464	CTD
G	GADD45A	growth arrest and DNA-damage-inducible, alpha		increases expression	EXP	1	68,150,860	68,154,021	RGD:6480464	CTD
G	GALM	galactose mutarotase (aldose 1-epimerase)		multiple interactions	EXP	2	38,893,052	38,961,909	RGD:6480464	CTD
G	GAPDH	glyceraldehyde-3-phosphate dehydrogenase		increases expression	EXP	12	6,643,585	6,647,537	RGD:6480464	CTD
G	GAS6	growth arrest-specific 6		multiple interactions	EXP	13	114,523,522	114,567,046	RGD:6480464	CTD
G	GAS6	growth arrest-specific 6		increases degradation	EXP	13	114,523,522	114,567,046	RGD:6480464	CTD
G	GCLC	glutamate-cysteine ligase, catalytic subunit		multiple interactions	EXP	6	53,362,139	53,409,927	RGD:6480464	CTD
G	GDF15	growth differentiation factor 15		multiple interactions	EXP	19	18,496,968	18,499,986	RGD:6480464	CTD
G	GPR137B	G protein-coupled receptor 137B		increases expression	EXP	1	236,305,832	236,372,209	RGD:6480464	CTD
G	GRM5	glutamate receptor, metabotropic 5		multiple interactions	ISO	11	88,237,744	88,796,816	RGD:6480464	CTD
G	GSTA1	glutathione S-transferase alpha 1		multiple interactions	ISO	6	52,656,178	52,668,664	RGD:6480464	CTD
G	GSTP1	glutathione S-transferase pi 1		decreases response to substance	ISO	11	67,351,066	67,354,124	RGD:6480464	CTD
G	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)		multiple interactions	EXP	14	62,162,119	62,214,977	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	ISO	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	ISO	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	ISO	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	ISO	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	ISO	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	ISO	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HMOX1	heme oxygenase (decycling) 1		multiple interactions	EXP	22	35,777,060	35,790,207	RGD:6480464	CTD
G	HNRNPA1	heterogeneous nuclear ribonucleoprotein A1		affects localization	ISO	12	54,674,488	54,679,030	RGD:6480464	CTD
G	HNRNPA1	heterogeneous nuclear ribonucleoprotein A1		multiple interactions	ISO	12	54,674,488	54,679,030	RGD:6480464	CTD
G	HOMER3	homer homolog 3 (Drosophila)		increases expression	EXP	19	19,040,010	19,052,041	RGD:6480464	CTD
G	HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog		multiple interactions	EXP	11	532,242	535,550	RGD:6480464	CTD
G	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)		multiple interactions	ISO	9	127,997,127	128,003,666	RGD:6480464	CTD
G	HTR3A	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic		multiple interactions	ISO	11	113,845,797	113,861,035	RGD:6480464	CTD
G	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein		multiple interactions	EXP	20	30,193,086	30,194,318	RGD:6480464	CTD
G	IER3	immediate early response 3		multiple interactions	EXP	6	30,710,976	30,712,327	RGD:6480464	CTD
G	IER5	immediate early response 5		increases expression	EXP	1	181,057,638	181,059,979	RGD:6480464	CTD
G	IFNA1	interferon, alpha 1		multiple interactions	EXP	9	21,440,453	21,441,315	RGD:6480464	CTD
G	IFNB1	interferon, beta 1, fibroblast		multiple interactions	EXP	9	21,077,104	21,077,943	RGD:6480464	CTD
G	IFNG	interferon, gamma		multiple interactions	EXP	12	68,548,550	68,553,521	RGD:6480464	CTD
G	IFNG	interferon, gamma		multiple interactions	EXP	12	68,548,550	68,553,521	RGD:6480464	CTD
G	IL10	interleukin 10		multiple interactions	ISO	1	206,940,948	206,945,839	RGD:6480464	CTD
G	IL11	interleukin 11		multiple interactions	EXP	19	55,875,750	55,881,831	RGD:6480464	CTD
G	IL17A	interleukin 17A		multiple interactions	ISO	6	52,051,185	52,055,436	RGD:6480464	CTD
G	IL17A	interleukin 17A		multiple interactions	ISO	6	52,051,185	52,055,436	RGD:6480464	CTD
G	IL1B	interleukin 1, beta		multiple interactions	EXP	2	113,587,337	113,594,356	RGD:6480464	CTD
G	IL1B	interleukin 1, beta		multiple interactions	EXP	2	113,587,337	113,594,356	RGD:6480464	CTD
G	IL1B	interleukin 1, beta		multiple interactions	EXP	2	113,587,337	113,594,356	RGD:6480464	CTD
G	IL1B	interleukin 1, beta		multiple interactions	EXP	2	113,587,337	113,594,356	RGD:6480464	CTD
G	IL1B	interleukin 1, beta		multiple interactions	ISO	2	113,587,337	113,594,356	RGD:6480464	CTD
G	IL1B	interleukin 1, beta		multiple interactions	ISO	2	113,587,337	113,594,356	RGD:6480464	CTD
G	IL1B	interleukin 1, beta		multiple interactions	EXP	2	113,587,337	113,594,356	RGD:6480464	CTD
G	IL27RA	interleukin 27 receptor, alpha		increases expression	EXP	19	14,142,552	14,163,731	RGD:6480464	CTD
G	IL8	interleukin 8		multiple interactions	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	IL8	interleukin 8		multiple interactions	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	IL8	interleukin 8		multiple interactions	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	IL8	interleukin 8		multiple interactions	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	IL8	interleukin 8		multiple interactions	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	IL8	interleukin 8		multiple interactions	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	IL8	interleukin 8		multiple interactions	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	IRF1	interferon regulatory factor 1		multiple interactions	EXP	5	131,817,301	131,826,465	RGD:6480464	CTD
G	IRF1	interferon regulatory factor 1		multiple interactions	EXP	5	131,817,301	131,826,465	RGD:6480464	CTD
G	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)		increases expression	EXP	17	42,449,550	42,466,873	RGD:6480464	CTD
G	ITPR1	inositol 1,4,5-trisphosphate receptor, type 1		multiple interactions	EXP	3	4,535,032	4,889,524	RGD:6480464	CTD
G	JAK2	Janus kinase 2		multiple interactions	ISO	9	4,985,245	5,128,183	RGD:6480464	CTD
G	JUN	jun proto-oncogene		multiple interactions	ISO	1	59,246,463	59,249,785	RGD:6480464	CTD
G	JUN	jun proto-oncogene		multiple interactions	ISO	1	59,246,463	59,249,785	RGD:6480464	CTD
G	JUN	jun proto-oncogene		decreases expression	ISO	1	59,246,463	59,249,785	RGD:6480464	CTD
G	JUN	jun proto-oncogene		multiple interactions	ISO	1	59,246,463	59,249,785	RGD:6480464	CTD
G	KIF1A	kinesin family member 1A		increases expression	EXP	2	241,653,181	241,759,725	RGD:6480464	CTD
G	KRT80	keratin 80		increases expression	EXP	12	52,562,780	52,585,784	RGD:6480464	CTD
G	LAMC2	laminin, gamma 2		increases expression	EXP	1	183,155,174	183,214,262	RGD:6480464	CTD
G	LEP	leptin		multiple interactions	ISO	7	127,881,331	127,897,682	RGD:6480464	CTD
G	LGALS3	lectin, galactoside-binding, soluble, 3		multiple interactions	EXP	14	55,595,935	55,612,148	RGD:6480464	CTD
G	LGALS7	lectin, galactoside-binding, soluble, 7		increases expression	EXP	19	39,261,608	39,264,157	RGD:6480464	CTD
G	LMNB1	lamin B1		decreases expression	EXP	5	126,112,315	126,172,712	RGD:6480464	CTD
G	MAP2K4	mitogen-activated protein kinase kinase 4		decreases expression	EXP	17	11,924,135	12,047,051	RGD:6480464	CTD
G	MAP3K7	mitogen-activated protein kinase kinase kinase 7		decreases expression	EXP	6	91,223,292	91,297,020	RGD:6480464	CTD
G	MAPK1	mitogen-activated protein kinase 1		multiple interactions	EXP	22	22,113,946	22,221,970	RGD:6480464	CTD
G	MAPK1	mitogen-activated protein kinase 1		increases expression	ISO	22	22,113,946	22,221,970	RGD:6480464	CTD
G	MAPK1	mitogen-activated protein kinase 1		multiple interactions	ISO	22	22,113,946	22,221,970	RGD:6480464	CTD
G	MAPK3	mitogen-activated protein kinase 3		multiple interactions	EXP	16	30,125,426	30,134,630	RGD:6480464	CTD
G	MAPK3	mitogen-activated protein kinase 3		multiple interactions	ISO	16	30,125,426	30,134,630	RGD:6480464	CTD
G	MAPK3	mitogen-activated protein kinase 3		increases expression	ISO	16	30,125,426	30,134,630	RGD:6480464	CTD
G	MCL1	myeloid cell leukemia sequence 1 (BCL2-related)		multiple interactions	EXP	1	150,547,027	150,552,214	RGD:6480464	CTD
G	MIR21	microRNA 21		multiple interactions	EXP	17	57,918,627	57,918,698	RGD:6480464	CTD
G	MIR21	microRNA 21		multiple interactions	EXP	17	57,918,627	57,918,698	RGD:6480464	CTD
G	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11		increases expression	EXP	1	151,032,151	151,040,973	RGD:6480464	CTD
G	MMP1	matrix metallopeptidase 1 (interstitial collagenase)		multiple interactions	EXP	11	102,660,641	102,668,966	RGD:6480464	CTD
G	MN1	meningioma (disrupted in balanced translocation) 1		multiple interactions	EXP	22	28,144,265	28,197,486	RGD:6480464	CTD
G	MRPL41	mitochondrial ribosomal protein L41		multiple interactions	EXP	9	140,446,309	140,447,007	RGD:6480464	CTD
G	MT2A	metallothionein 2A		multiple interactions	EXP	16	56,642,478	56,643,409	RGD:6480464	CTD
G	MTTP	microsomal triglyceride transfer protein		multiple interactions	ISO	4	100,485,240	100,545,154	RGD:6480464	CTD
G	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)		decreases expression	EXP	8	128,748,315	128,753,680	RGD:6480464	CTD
G	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)		decreases expression	EXP	8	128,748,315	128,753,680	RGD:6480464	CTD
G	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)		multiple interactions	ISO	8	128,748,315	128,753,680	RGD:6480464	CTD
G	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)		decreases expression	ISO	8	128,748,315	128,753,680	RGD:6480464	CTD
G	MYLK	myosin light chain kinase		multiple interactions	EXP	3	123,331,143	123,603,149	RGD:6480464	CTD
G	NAV2	neuron navigator 2		multiple interactions	EXP	11	19,372,271	20,143,147	RGD:6480464	CTD
G	NCF1	neutrophil cytosolic factor 1		multiple interactions	EXP	7	74,188,309	74,203,659	RGD:6480464	CTD
G	NDRG1	N-myc downstream regulated 1		multiple interactions	ISO	8	134,249,414	134,309,547	RGD:6480464	CTD
G	NEDD9	neural precursor cell expressed, developmentally down-regulated 9		multiple interactions	EXP	6	11,183,531	11,382,581	RGD:6480464	CTD
G	NETO2	neuropilin (NRP) and tolloid (TLL)-like 2		increases expression	EXP	16	47,115,431	47,177,936	RGD:6480464	CTD
G	NFE2L2	nuclear factor (erythroid-derived 2)-like 2		multiple interactions	EXP	2	178,095,031	178,129,859	RGD:6480464	CTD
G	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		decreases expression	EXP	4	103,422,486	103,538,459	RGD:6480464	CTD
G	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	EXP	4	103,422,486	103,538,459	RGD:6480464	CTD
G	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha		multiple interactions	EXP	14	35,870,716	35,873,960	RGD:6480464	CTD
G	NOS2	nitric oxide synthase 2, inducible		multiple interactions	ISO	17	26,083,792	26,127,555	RGD:6480464	CTD
G	NPPC	natriuretic peptide C		multiple interactions	ISO	2	232,786,805	232,791,038	RGD:6480464	CTD
G	NQO1	NAD(P)H dehydrogenase, quinone 1		multiple interactions	ISO	16	69,743,304	69,760,533	RGD:6480464	CTD
G	NQO1	NAD(P)H dehydrogenase, quinone 1		multiple interactions	ISO	16	69,743,304	69,760,533	RGD:6480464	CTD
G	NQO1	NAD(P)H dehydrogenase, quinone 1		multiple interactions	ISO	16	69,743,304	69,760,533	RGD:6480464	CTD
G	NQO1	NAD(P)H dehydrogenase, quinone 1		multiple interactions	ISO	16	69,743,304	69,760,533	RGD:6480464	CTD
G	NR0B2	nuclear receptor subfamily 0, group B, member 2		multiple interactions	EXP	1	27,237,975	27,240,567	RGD:6480464	CTD
G	NR1I2	nuclear receptor subfamily 1, group I, member 2		multiple interactions	ISO	3	119,499,331	119,537,332	RGD:6480464	CTD
G	NR1I2	nuclear receptor subfamily 1, group I, member 2		multiple interactions	ISO	3	119,499,331	119,537,332	RGD:6480464	CTD
G	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)		multiple interactions	ISO	5	142,657,496	142,815,077	RGD:6480464	CTD
G	NTHL1	nth endonuclease III-like 1 (E. coli)		decreases expression	EXP	16	2,089,816	2,097,867	RGD:6480464	CTD
G	PAPPA	pregnancy-associated plasma protein A, pappalysin 1		multiple interactions	EXP	9	118,916,071	119,164,600	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		multiple interactions	EXP	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		multiple interactions	EXP	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		multiple interactions	ISO	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PCNA	proliferating cell nuclear antigen		decreases expression	ISO	20	5,095,599	5,107,268	RGD:6480464	CTD
G	PCNA	proliferating cell nuclear antigen		multiple interactions	EXP	20	5,095,599	5,107,268	RGD:6480464	CTD
G	PLAT	plasminogen activator, tissue		multiple interactions	EXP	8	42,032,236	42,065,194	RGD:6480464	CTD
G	PLAU	plasminogen activator, urokinase		multiple interactions	EXP	10	75,670,862	75,677,259	RGD:6480464	CTD
G	PLAU	plasminogen activator, urokinase		increases expression	EXP	10	75,670,862	75,677,259	RGD:6480464	CTD
G	PLD1	phospholipase D1, phosphatidylcholine-specific		multiple interactions	EXP	3	171,318,195	171,528,284	RGD:6480464	CTD
G	PLD2	phospholipase D2		multiple interactions	ISO	17	4,710,396	4,726,727	RGD:6480464	CTD
G	POMT1	protein-O-mannosyltransferase 1		increases expression	EXP	9	134,378,289	134,399,193	RGD:6480464	CTD
G	PRDX1	peroxiredoxin 1		multiple interactions	ISO	1	45,976,707	45,988,562	RGD:6480464	CTD
G	PRDX6	peroxiredoxin 6		multiple interactions	ISO	1	173,446,486	173,457,946	RGD:6480464	CTD
G	PRKCD	protein kinase C, delta		multiple interactions	EXP	3	53,195,223	53,226,733	RGD:6480464	CTD
G	PRKCD	protein kinase C, delta		multiple interactions	ISO	3	53,195,223	53,226,733	RGD:6480464	CTD
G	PRL	prolactin		multiple interactions	ISO	6	22,287,473	22,303,082	RGD:6480464	CTD
G	PROCR	protein C receptor, endothelial		increases expression	EXP	20	33,759,774	33,765,165	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	EXP	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	ISO	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		decreases expression	ISO	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	ISO	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	EXP	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	ISO	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	EXP	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	EXP	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTK2	protein tyrosine kinase 2		decreases expression	ISO	8	141,668,481	142,011,412	RGD:6480464	CTD
G	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)		multiple interactions	EXP	2	61,108,752	61,150,178	RGD:6480464	CTD
G	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	EXP	11	65,421,067	65,430,443	RGD:6480464	CTD
G	REN	renin		multiple interactions	EXP	1	204,123,944	204,135,465	RGD:6480464	CTD
G	RETSAT	retinol saturase (all-trans-retinol 13,14-reductase)		increases expression	EXP	2	85,569,078	85,581,821	RGD:6480464	CTD
G	RNY1	RNA, Ro-associated Y1		increases degradation	EXP	7	148,684,228	148,684,340	RGD:6480464	CTD
G	RNY3	RNA, Ro-associated Y3		increases degradation	EXP	7	148,680,847	148,680,948	RGD:6480464	CTD
G	RNY4	RNA, Ro-associated Y4		increases degradation	EXP	7	148,660,407	148,660,502	RGD:6480464	CTD
G	RNY5	RNA, Ro-associated Y5		increases degradation	EXP	7	148,638,580	148,638,663	RGD:6480464	CTD
G	ROS1	c-ros oncogene 1 , receptor tyrosine kinase		increases expression	EXP	6	117,609,530	117,747,018	RGD:6480464	CTD
G	RPL34	ribosomal protein L34		increases expression	EXP	4	109,541,722	109,551,640	RGD:6480464	CTD
G	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1		multiple interactions	EXP	17	57,970,443	58,027,787	RGD:6480464	CTD
G	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1		multiple interactions	ISO	17	57,970,443	58,027,787	RGD:6480464	CTD
G	RRAS	related RAS viral (r-ras) oncogene homolog		increases expression	EXP	19	50,138,552	50,143,400	RGD:6480464	CTD
G	SAT1	spermidine/spermine N1-acetyltransferase 1		multiple interactions	EXP	X	23,801,275	23,804,327	RGD:6480464	CTD
G	SCNN1B	sodium channel, non-voltage-gated 1, beta subunit		multiple interactions	EXP	16	23,313,591	23,392,620	RGD:6480464	CTD
G	SCNN1G	sodium channel, non-voltage-gated 1, gamma subunit		multiple interactions	EXP	16	23,194,040	23,228,200	RGD:6480464	CTD
G	SDC3	syndecan 3		multiple interactions	ISO	1	31,342,313	31,381,480	RGD:6480464	CTD
G	SFN	stratifin		increases expression	EXP	1	27,189,633	27,190,947	RGD:6480464	CTD
G	SLC25A14	solute carrier family 25 (mitochondrial carrier, brain), member 14		multiple interactions	EXP	X	129,474,047	129,507,335	RGD:6480464	CTD
G	SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2		multiple interactions	ISO	3	170,714,137	170,744,768	RGD:6480464	CTD
G	SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5		multiple interactions	ISO	1	9,097,005	9,129,887	RGD:6480464	CTD
G	SLC30A2	solute carrier family 30 (zinc transporter), member 2		multiple interactions	ISO	1	26,364,514	26,372,604	RGD:6480464	CTD
G	SLC30A5	solute carrier family 30 (zinc transporter), member 5		multiple interactions	EXP	5	68,389,776	68,426,899	RGD:6480464	CTD
G	SLC39A10	solute carrier family 39 (zinc transporter), member 10		multiple interactions	ISO	2	196,521,532	196,602,426	RGD:6480464	CTD
G	SLC39A4	solute carrier family 39 (zinc transporter), member 4		multiple interactions	ISO	8	145,637,798	145,642,273	RGD:6480464	CTD
G	SOD2	superoxide dismutase 2, mitochondrial		multiple interactions	EXP	6	160,100,148	160,114,353	RGD:6480464	CTD
G	SOD2	superoxide dismutase 2, mitochondrial		multiple interactions	EXP	6	160,100,148	160,114,353	RGD:6480464	CTD
G	SOD2	superoxide dismutase 2, mitochondrial		multiple interactions	EXP	6	160,100,148	160,114,353	RGD:6480464	CTD
G	SOD2	superoxide dismutase 2, mitochondrial		multiple interactions	ISO	6	160,100,148	160,114,353	RGD:6480464	CTD
G	SOD2	superoxide dismutase 2, mitochondrial		multiple interactions	ISO	6	160,100,148	160,114,353	RGD:6480464	CTD
G	SOS1	son of sevenless homolog 1 (Drosophila)		decreases expression	EXP	2	39,208,690	39,347,604	RGD:6480464	CTD
G	SPATA18	spermatogenesis associated 18		increases expression	EXP	4	52,917,593	52,963,458	RGD:6480464	CTD
G	STAT1	signal transducer and activator of transcription 1, 91kDa		increases expression	EXP	2	191,833,762	191,878,976	RGD:6480464	CTD
G	STMN3	stathmin-like 3		increases expression	EXP	20	62,271,061	62,284,780	RGD:6480464	CTD
G	STOM	stomatin		increases expression	EXP	9	124,101,266	124,132,582	RGD:6480464	CTD
G	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1		multiple interactions	EXP	16	28,616,908	28,634,907	RGD:6480464	CTD
G	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)		increases expression	EXP	6	32,812,986	32,821,748	RGD:6480464	CTD
G	TAT	tyrosine aminotransferase		multiple interactions	ISO	16	71,600,754	71,610,998	RGD:6480464	CTD
G	TAT	tyrosine aminotransferase		multiple interactions	ISO	16	71,600,754	71,610,998	RGD:6480464	CTD
G	TCF4	transcription factor 4		multiple interactions	ISO	18	52,889,562	53,303,188	RGD:6480464	CTD
G	TDO2	tryptophan 2,3-dioxygenase		affects activity	ISO	4	156,824,845	156,841,558	RGD:6480464	CTD
G	TGFB1	transforming growth factor, beta 1		multiple interactions	EXP	19	41,836,812	41,859,831	RGD:6480464	CTD
G	TGFB1	transforming growth factor, beta 1		multiple interactions	EXP	19	41,836,812	41,859,831	RGD:6480464	CTD
G	TGFB2	transforming growth factor, beta 2		multiple interactions	EXP	1	218,518,676	218,617,961	RGD:6480464	CTD
G	THRA	thyroid hormone receptor, alpha		multiple interactions	ISO	17	38,218,446	38,250,120	RGD:6480464	CTD
G	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase		multiple interactions	ISO	3	156,392,205	156,424,559	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	ISO	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		increases response to substance	EXP	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	ISO	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	ISO	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	ISO	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNFAIP3	tumor necrosis factor, alpha-induced protein 3		multiple interactions	EXP	6	138,188,325	138,204,451	RGD:6480464	CTD
G	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b		decreases expression	EXP	8	22,877,646	22,926,700	RGD:6480464	CTD
G	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b		multiple interactions	EXP	8	22,877,646	22,926,700	RGD:6480464	CTD
G	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10		multiple interactions	EXP	3	172,223,298	172,241,297	RGD:6480464	CTD
G	TNFSF9	tumor necrosis factor (ligand) superfamily, member 9		increases expression	EXP	19	6,531,010	6,535,939	RGD:6480464	CTD
G	TOP1	topoisomerase (DNA) I		increases activity	ISO	20	39,657,462	39,753,127	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		increases activity	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		increases expression	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		increases expression	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		increases activity	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53I11	tumor protein p53 inducible protein 11		multiple interactions	EXP	11	44,953,899	44,972,857	RGD:6480464	CTD
G	TP53I11	tumor protein p53 inducible protein 11		decreases expression	EXP	11	44,953,899	44,972,857	RGD:6480464	CTD
G	TRPV6	transient receptor potential cation channel, subfamily V, member 6		multiple interactions	EXP	7	142,568,960	142,583,490	RGD:6480464	CTD
G	TUBA4A	tubulin, alpha 4a		increases expression	EXP	2	220,115,001	220,118,638	RGD:6480464	CTD
G	TXNRD1	thioredoxin reductase 1		multiple interactions	EXP	12	104,609,557	104,744,085	RGD:6480464	CTD
G	TXNRD1	thioredoxin reductase 1		multiple interactions	EXP	12	104,609,557	104,744,085	RGD:6480464	CTD
G	TYMP	thymidine phosphorylase		multiple interactions	EXP	22	50,964,181	50,968,514	RGD:6480464	CTD
G	TYR	tyrosinase		multiple interactions	EXP	11	88,911,040	89,028,927	RGD:6480464	CTD
G	TYR	tyrosinase		multiple interactions	ISO	11	88,911,040	89,028,927	RGD:6480464	CTD
G	VCAM1	vascular cell adhesion molecule 1		multiple interactions	ISO	1	101,185,196	101,204,601	RGD:6480464	CTD
G	VEGFA	vascular endothelial growth factor A		multiple interactions	EXP	6	43,737,946	43,754,224	RGD:6480464	CTD
G	VEGFA	vascular endothelial growth factor A		multiple interactions	EXP	6	43,737,946	43,754,224	RGD:6480464	CTD
G	VEGFA	vascular endothelial growth factor A		multiple interactions	ISO	6	43,737,946	43,754,224	RGD:6480464	CTD
G	VEGFA	vascular endothelial growth factor A		multiple interactions	ISO	6	43,737,946	43,754,224	RGD:6480464	CTD
G	VEGFA	vascular endothelial growth factor A		multiple interactions	EXP	6	43,737,946	43,754,224	RGD:6480464	CTD
G	VMP1	vacuole membrane protein 1		decreases expression	EXP	17	57,784,863	57,917,954	RGD:6480464	CTD
G	VMP1	vacuole membrane protein 1		multiple interactions	EXP	17	57,784,863	57,917,954	RGD:6480464	CTD
G	XIAP	X-linked inhibitor of apoptosis		decreases expression	EXP	X	122,993,662	123,047,829	RGD:6480464	CTD

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	513708
role	503229
biological role	501402
aetiopathogenetic role	114227
mutagen	19165
actinomycin D	373
Path 2
Term	Annotations
CHEBI ontology	513708
subatomic particle	512601
composite particle	512601
hadron	512601
baryon	512601
nucleon	512601
atomic nucleus	512601
atom	512601
main group element atom	480609
p-block element atom	478027
carbon group element atom	427614
carbon atom	424022
organic molecular entity	424015
organic group	174681
organic divalent group	173480
organodiyl group	173480
carbonyl group	173163
carbonyl compound	173163
carboxylic acid	126604
carboacyl group	43094
univalent carboacyl group	43094
carbamoyl group	39024
carboxamide	39014
peptide	10654
peptide antibiotic	1591
chromopeptide	373
actinomycin	373
actinomycin D	373