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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731748 Species: Homo sapiens RGD Object: Gene Symbol: JAK2 Name: Janus kinase 2

Acc ID: CHEBI:27666 Term: actinomycin D Definition: An actinomycin that has formula C62H86N12O16. CasRN: 50-76-0 Chemical ID: MESH:D003609

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:2939	6480464	CTD	Dactinomycin inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein]	PMID:15932931