CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-chloro-2,4-dinitrobenzene
Accession: CHEBI:34718
browse the term
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Synonyms: related_synonym: 1,3-Dinitro-4-chlorobenzene; 1-Chloro-2,4-dinitrobenzol; 2,4-Dinitro-1-chlorobenzene; 2,4-Dinitrochlorobenzene; 2,4-Dinitrophenyl chloride; 4-Chloro-1,3-dinitrobenzene; 6-Chloro-1,3-dinitrobenzene; Cdnb; Chlorodinitrobenzene; ClDNB; DNPCl; Dinitrochlorobenzene; Dncb; Formula=C6H3ClN2O4; InChI=1S/C6H3ClN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H; InChIKey=VYZAHLCBVHPDDF-UHFFFAOYSA-N; SMILES=[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O
xref: Beilstein:613161; CAS:97-00-7; Gmelin:28481; KEGG:C14397
xref_mesh: MESH:D004137
xref: PMID:1155304; PMID:12176098; PMID:1447476; PMID:15009707; PMID:15588915; PMID:1640019; PMID:18316151; PMID:18775882; PMID:19171927; PMID:1982449; PMID:25515858; PMID:29079364; PMID:3180787; PMID:6446435; PMID:7059096; PMID:7179722; PMID:7994925; Reaxys:613161; Wikipedia:2\,4-Dinitrochlorobenzene
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Aars1
alanyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to AARS1 protein
CTD
PMID:32991956
NCBI chr 8:111,759,781...111,784,237
Ensembl chr 8:111,759,776...111,784,296
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Abca6
ATP-binding cassette, sub-family A member 6
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ABCA6 mRNA
CTD
PMID:17374397
NCBI chr11:110,065,464...110,142,811
Ensembl chr11:110,067,646...110,142,602
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Abcc2
ATP-binding cassette, sub-family member 2
decreases response to substance
ISO
ABCC2 protein results in decreased susceptibility to Dinitrochlorobenzene
CTD
PMID:26049102
NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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Abhd10
abhydrolase domain containing 10
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ABHD10 mRNA
CTD
PMID:17374397
NCBI chr16:45,550,088...45,563,355
Ensembl chr16:45,550,088...45,563,318
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Abhd11
abhydrolase domain containing 11
affects binding
ISO
Dinitrochlorobenzene binds to ABHD11 protein
CTD
PMID:32991956
NCBI chr 5:135,038,006...135,041,029
Ensembl chr 5:135,038,006...135,041,029
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Acat2
acetyl-Coenzyme A acetyltransferase 2
affects binding
ISO
Dinitrochlorobenzene binds to ACAT2 protein
CTD
PMID:32991956
NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
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Acly
ATP citrate lyase
affects binding
ISO
Dinitrochlorobenzene binds to ACLY protein
CTD
PMID:32991956
NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826
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Acod1
aconitate decarboxylase 1
affects expression
EXP
Dinitrochlorobenzene affects the expression of ACOD1 mRNA
CTD
PMID:22302311
NCBI chr14:103,284,448...103,294,009
Ensembl chr14:103,284,413...103,294,009
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Acox2
acyl-Coenzyme A oxidase 2, branched chain
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ACOX2 mRNA
CTD
PMID:16314067
NCBI chr14:14,210,406...14,244,262
Ensembl chr14:14,210,420...14,244,262
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Acp1
acid phosphatase 1, soluble
affects binding
ISO
Dinitrochlorobenzene binds to ACP1 protein
CTD
PMID:32991956
NCBI chr12:30,943,325...30,961,616
Ensembl chr12:30,943,325...30,961,588
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Acsl1
acyl-CoA synthetase long-chain family member 1
affects binding
ISO
Dinitrochlorobenzene binds to ACSL1 protein
CTD
PMID:32991956
NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
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Acsl4
acyl-CoA synthetase long-chain family member 4
affects binding
ISO
Dinitrochlorobenzene binds to ACSL4 protein
CTD
PMID:32991956
NCBI chr X:141,100,989...141,173,792
Ensembl chr X:141,100,989...141,173,531
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Actb
actin, beta
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of ACTB protein Dinitrochlorobenzene binds to ACTB protein
CTD
PMID:29267982 PMID:32991956
NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
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Adamts15
ADAM metallopeptidase with thrombospondin type 1 motif 15
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ADAMTS15 mRNA
CTD
PMID:19647056
NCBI chr 9:30,810,451...30,833,853
Ensembl chr 9:30,810,451...30,833,748
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Adm
adrenomedullin
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ADM mRNA
CTD
PMID:25236440
NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
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Adnp2
ADNP homeobox 2
affects binding
ISO
Dinitrochlorobenzene binds to ADNP2 protein
CTD
PMID:32991956
NCBI chr18:80,169,523...80,195,284
Ensembl chr18:80,169,526...80,194,697
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Adora2b
adenosine A2b receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ADORA2B mRNA
CTD
PMID:16314067
NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279
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Adsl
adenylosuccinate lyase
affects binding
ISO
Dinitrochlorobenzene binds to ADSL protein
CTD
PMID:32991956
NCBI chr15:80,832,691...80,855,148
Ensembl chr15:80,832,691...80,855,147
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Afg2b
AFG2 AAA ATPase homolog B
affects binding
ISO
Dinitrochlorobenzene binds to AFG2B protein
CTD
PMID:32991956
NCBI chr 2:122,461,112...122,474,933
Ensembl chr 2:122,461,120...122,474,750
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Aicda
activation-induced cytidine deaminase
affects expression
EXP
Dinitrochlorobenzene affects the expression of AICDA mRNA
CTD
PMID:22302311
NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139
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Aifm1
apoptosis-inducing factor, mitochondrion-associated 1
affects binding
ISO
Dinitrochlorobenzene binds to AIFM1 protein
CTD
PMID:32991956
NCBI chr X:47,563,821...47,602,440
Ensembl chr X:47,563,821...47,602,440
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Akap13
A kinase anchor protein 13
affects binding
ISO
Dinitrochlorobenzene binds to AKAP13 protein
CTD
PMID:32991956
NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357
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Akr1b1
aldo-keto reductase family 1 member B
increases expression
ISO
Dinitrochlorobenzene results in increased expression of AKR1B1 mRNA
CTD
PMID:20566472
NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413
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Akr1b10
aldo-keto reductase family 1, member B10
increases expression
ISO
Dinitrochlorobenzene results in increased expression of AKR1B10 mRNA
CTD
PMID:20566472
NCBI chr 6:34,361,182...34,373,884
Ensembl chr 6:34,361,153...34,373,885
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Akr1c18
aldo-keto reductase family 1, member C18
increases expression affects expression
ISO EXP
Dinitrochlorobenzene results in increased expression of AKR1C3 mRNA Dinitrochlorobenzene affects the expression of AKR1C18 mRNA
CTD
PMID:20566472 PMID:22302311
NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
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Akr1c20
aldo-keto reductase family 1, member C20
increases expression
ISO
Dinitrochlorobenzene results in increased expression of AKR1C1 mRNA
CTD
PMID:20566472
NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344
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Akr1c21
aldo-keto reductase family 1, member C21
increases activity increases expression
ISO
Dinitrochlorobenzene results in increased activity of AKR1C2 promoter Dinitrochlorobenzene results in increased expression of AKR1C2 mRNA
CTD
PMID:20491607 PMID:20713136 PMID:21195160
NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540
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Akt2
thymoma viral proto-oncogene 2
affects binding
ISO
Dinitrochlorobenzene binds to AKT2 protein
CTD
PMID:32991956
NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
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Alb
albumin
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of ALB protein
CTD
PMID:29267982
NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
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Ankrd12
ankyrin repeat domain 12
affects binding
ISO
Dinitrochlorobenzene binds to ANKRD12 protein
CTD
PMID:32991956
NCBI chr17:66,272,698...66,386,242
Ensembl chr17:66,272,693...66,384,084
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Ankrd2
ankyrin repeat domain 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ANKRD2 mRNA
CTD
PMID:19647056
NCBI chr19:42,024,358...42,033,550
Ensembl chr19:42,024,439...42,033,549
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Ankrd35
ankyrin repeat domain 35
affects binding
ISO
Dinitrochlorobenzene binds to ANKRD35 protein
CTD
PMID:32991956
NCBI chr 3:96,577,447...96,598,350
Ensembl chr 3:96,577,447...96,598,348
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Ankrd37
ankyrin repeat domain 37
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ANKRD37 mRNA
CTD
PMID:25236440
NCBI chr 8:46,449,945...46,452,904
Ensembl chr 8:46,449,939...46,458,744
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Anxa1
annexin A1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ANXA1 mRNA
CTD
PMID:16314067
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
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Anxa2
annexin A2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ANXA2 mRNA
CTD
PMID:16314067
NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077
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Anxa3
annexin A3
affects binding
ISO
Dinitrochlorobenzene binds to ANXA3 protein
CTD
PMID:32991956
NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
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Ap1b1
adaptor protein complex AP-1, beta 1 subunit
affects binding
ISO
Dinitrochlorobenzene binds to AP1B1 protein
CTD
PMID:32991956
NCBI chr11:4,897,320...4,992,731
Ensembl chr11:4,936,824...4,992,791
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Ap2a1
adaptor-related protein complex 2, alpha 1 subunit
affects binding
ISO
Dinitrochlorobenzene binds to AP2A1 protein
CTD
PMID:32991956
NCBI chr 7:44,549,797...44,578,914
Ensembl chr 7:44,549,797...44,578,920
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Ap2b1
adaptor-related protein complex 2, beta 1 subunit
affects binding
ISO
Dinitrochlorobenzene binds to AP2B1 protein
CTD
PMID:32991956
NCBI chr11:83,189,545...83,295,861
Ensembl chr11:83,189,850...83,295,861
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Ap3d1
adaptor-related protein complex 3, delta 1 subunit
affects binding
ISO
Dinitrochlorobenzene binds to AP3D1 protein
CTD
PMID:32991956
NCBI chr10:80,542,790...80,578,137
Ensembl chr10:80,542,790...80,578,098
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Aqr
aquarius
affects binding
ISO
Dinitrochlorobenzene binds to AQR protein
CTD
PMID:32991956
NCBI chr 2:113,931,642...114,005,788
Ensembl chr 2:113,931,651...114,017,505
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Arf5
ADP-ribosylation factor 5
affects binding
ISO
Dinitrochlorobenzene binds to ARF5 protein
CTD
PMID:32991956
NCBI chr 6:28,423,603...28,426,601
Ensembl chr 6:28,423,559...28,426,601
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Arg2
arginase type II
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ARG2 mRNA
CTD
PMID:16314067
NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
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Arl4c
ADP-ribosylation factor-like 4C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ARL4C mRNA
CTD
PMID:17374397
NCBI chr 1:88,625,947...88,629,913
Ensembl chr 1:88,600,847...88,629,943
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Arpc2
actin related protein 2/3 complex, subunit 2
affects binding
ISO
Dinitrochlorobenzene binds to ARPC2 protein
CTD
PMID:32991956
NCBI chr 1:74,275,656...74,307,368
Ensembl chr 1:74,275,243...74,307,368
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Arpc3
actin related protein 2/3 complex, subunit 3
affects binding
ISO
Dinitrochlorobenzene binds to ARPC3 protein
CTD
PMID:32991956
NCBI chr 5:122,529,941...122,544,244
Ensembl chr 5:122,529,941...122,552,247
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Asns
asparagine synthetase
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ASNS mRNA
CTD
PMID:18242016
NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
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Ass1
argininosuccinate synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to ASS1 protein
CTD
PMID:32991956
NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684
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Atf3
activating transcription factor 3
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of ATF3 mRNA KN 62 inhibits the reaction [Dinitrochlorobenzene results in increased expression of ATF3 mRNA]
CTD
PMID:23999411 PMID:27965148 PMID:28941582
NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
affects binding
ISO
Dinitrochlorobenzene binds to ATIC protein
CTD
PMID:32991956
NCBI chr 1:71,596,315...71,618,562
Ensembl chr 1:71,596,309...71,618,790
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Atp5f1a
ATP synthase F1 subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to ATP5F1A protein
CTD
PMID:32991956
NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
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Azin1
antizyme inhibitor 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of AZIN1 mRNA
CTD
PMID:17374397
NCBI chr15:38,487,674...38,523,506
Ensembl chr15:38,487,671...38,519,510
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B2m
beta-2 microglobulin
affects expression
EXP
Dinitrochlorobenzene affects the expression of B2M mRNA
CTD
PMID:28219650
NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
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Bach1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
multiple interactions
ISO
BACH1 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]
CTD
PMID:26244607
NCBI chr16:87,495,842...87,530,234
Ensembl chr16:87,495,833...87,530,234
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Bambi
BMP and activin membrane-bound inhibitor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BAMBI mRNA
CTD
PMID:20146380
NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404
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Bcl2
B cell leukemia/lymphoma 2
multiple interactions affects expression
EXP
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of BCL2 mRNA] Dinitrochlorobenzene affects the expression of BCL2 mRNA
CTD
PMID:28219650
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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Bclaf1
BCL2-associated transcription factor 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of BCLAF1 mRNA
CTD
PMID:17374397
NCBI chr10:20,187,897...20,218,390
Ensembl chr10:20,188,215...20,220,359
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Bdnf
brain derived neurotrophic factor
multiple interactions
ISO
Dinitrochlorobenzene inhibits the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid]
CTD
PMID:19428112
NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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Bmp6
bone morphogenetic protein 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BMP6 mRNA
CTD
PMID:17374397
NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
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Bspry
B-box and SPRY domain containing
increases expression
EXP
Dinitrochlorobenzene results in increased expression of BSPRY mRNA
CTD
PMID:18242016
NCBI chr 4:62,398,248...62,415,537
Ensembl chr 4:62,398,290...62,415,535
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Bst2
bone marrow stromal cell antigen 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of BST2 mRNA
CTD
PMID:19647056
NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100
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Btg1
BTG anti-proliferation factor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BTG1 mRNA
CTD
PMID:17374397
NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671
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Bub1
BUB1, mitotic checkpoint serine/threonine kinase
decreases expression increases expression
ISO EXP
Dinitrochlorobenzene results in decreased expression of BUB1 mRNA Dinitrochlorobenzene results in increased expression of BUB1 mRNA
CTD
PMID:17374397 PMID:21404309
NCBI chr 2:127,642,117...127,673,790
Ensembl chr 2:127,643,036...127,673,785
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Bub1b
BUB1B, mitotic checkpoint serine/threonine kinase
increases expression
EXP
Dinitrochlorobenzene results in increased expression of BUB1B mRNA
CTD
PMID:21404309
NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072
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C3
complement component 3
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of C3 protein
CTD
PMID:29267982
NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
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Calca
calcitonin/calcitonin-related polypeptide, alpha
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CALCA mRNA
CTD
PMID:20146380
NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
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Calcrl
calcitonin receptor-like
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CALCRL mRNA
CTD
PMID:17374397
NCBI chr 2:84,160,970...84,255,786
Ensembl chr 2:84,160,970...84,255,755
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Canx
calnexin
affects binding
ISO
Dinitrochlorobenzene binds to CANX protein
CTD
PMID:32991956
NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
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Capza2
capping actin protein of muscle Z-line subunit alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to CAPZA2 protein
CTD
PMID:32991956
NCBI chr 6:17,637,009...17,666,971
Ensembl chr 6:17,636,233...17,666,971
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Car2
carbonic anhydrase 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CA2 mRNA
CTD
PMID:17374397
NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
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Casp1
caspase 1
increases expression increases phosphorylation multiple interactions increases activity
EXP ISO
Dinitrochlorobenzene results in increased expression of CASP1 mRNA Dinitrochlorobenzene results in increased phosphorylation of CASP1 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] Dinitrochlorobenzene results in increased activity of CASP1 protein
CTD
PMID:28219650 PMID:30842373 PMID:31276767
NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
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Casp3
caspase 3
decreases expression increases expression multiple interactions
EXP
Dinitrochlorobenzene results in decreased expression of CASP3 mRNA Dinitrochlorobenzene results in increased expression of CASP3 mRNA; Dinitrochlorobenzene results in increased expression of CASP3 protein sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 protein]
CTD
PMID:28219650 PMID:34651546
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Casp8ap2
caspase 8 associated protein 2
affects binding
ISO
Dinitrochlorobenzene binds to CASP8AP2 protein
CTD
PMID:32991956
NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
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Casp9
caspase 9
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of CASP9 mRNA
CTD
PMID:28219650
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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Cat
catalase
increases expression multiple interactions decreases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CAT mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of CAT mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of CAT protein]
CTD
PMID:20566472 PMID:28219650 PMID:34651546
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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Ccl11
C-C motif chemokine ligand 11
multiple interactions increases expression
EXP
Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL11 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL11 mRNA]
CTD
PMID:23133493
NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
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Ccl12
C-C motif chemokine ligand 12
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCL12 mRNA
CTD
PMID:19647056
NCBI chr11:81,992,671...81,994,225
Ensembl chr11:81,992,671...81,994,226
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Ccl17
C-C motif chemokine ligand 17
multiple interactions increases expression
EXP
diflorasone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 protein]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 protein] Dinitrochlorobenzene results in increased expression of CCL17 mRNA; Dinitrochlorobenzene results in increased expression of CCL17 protein
CTD
PMID:15491423 PMID:21404309 PMID:23454147
NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
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Ccl19
C-C motif chemokine ligand 19
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCL19 mRNA
CTD
PMID:21404309
NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577
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Ccl2
C-C motif chemokine ligand 2
decreases expression decreases secretion increases secretion increases expression multiple interactions
ISO EXP
Dinitrochlorobenzene results in decreased expression of CCL2 mRNA Dinitrochlorobenzene results in decreased secretion of CCL2 protein Dinitrochlorobenzene results in increased secretion of CCL2 protein Dinitrochlorobenzene results in increased expression of CCL2 mRNA Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL2 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL2 mRNA]
CTD
PMID:15585374 PMID:17374397 PMID:19647056 PMID:20488241 PMID:20713136 PMID:21404309 PMID:22245253 PMID:23133493 More...
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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Ccl20
C-C motif chemokine ligand 20
affects expression
EXP
Dinitrochlorobenzene affects the expression of CCL20 mRNA
CTD
PMID:28219650
NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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Ccl21b
C-C motif chemokine ligand 21B (leucine)
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of CCL21B mRNA
CTD
PMID:21404309
NCBI chr 4:42,173,120...42,256,825
Ensembl chr 4:42,255,693...42,256,825
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Ccl21d
C-C motif chemokine ligand 21D
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of CCL21D mRNA
CTD
PMID:18242016
NCBI chr 4:41,896,187...41,904,743
Ensembl chr 4:41,903,610...41,904,743
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Ccl22
C-C motif chemokine ligand 22
affects expression
EXP
Dinitrochlorobenzene affects the expression of CCL22 mRNA
CTD
PMID:28219650
NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327
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Ccl3
C-C motif chemokine ligand 3
increases expression affects expression multiple interactions
ISO EXP
Dinitrochlorobenzene results in increased expression of CCL3 mRNA Dinitrochlorobenzene affects the expression of CCL3 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL3 mRNA]
CTD
PMID:15585374 PMID:19647056 PMID:20146380 PMID:28219650
NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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Ccl4
C-C motif chemokine ligand 4
increases expression increases secretion
EXP ISO
Dinitrochlorobenzene results in increased expression of CCL4 mRNA Dinitrochlorobenzene results in increased expression of CCL4 mRNA; Dinitrochlorobenzene results in increased expression of CCL4 protein Dinitrochlorobenzene results in increased secretion of CCL4 protein
CTD
PMID:15585374 PMID:16314067 PMID:18353026 PMID:19647056 PMID:20146380 PMID:28219650 More...
NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
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Ccl5
C-C motif chemokine ligand 5
multiple interactions increases expression increases secretion decreases expression
EXP ISO
diflorasone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL5 protein] Dinitrochlorobenzene results in increased secretion of CCL5 protein Dinitrochlorobenzene results in decreased expression of CCL5 mRNA
CTD
PMID:15491423 PMID:20488241 PMID:21404309 PMID:28219650
NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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Ccl6
C-C motif chemokine ligand 6
affects expression increases expression
EXP
Dinitrochlorobenzene affects the expression of CCL6 mRNA Dinitrochlorobenzene results in increased expression of CCL6 mRNA
CTD
PMID:19647056 PMID:21404309 PMID:22302311
NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CCL7 mRNA
CTD
PMID:19647056 PMID:21404309 PMID:21893156
NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
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Ccl8
C-C motif chemokine ligand 8
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCL8 mRNA
CTD
PMID:19647056
NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625
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Ccl9
C-C motif chemokine ligand 9
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCL9 mRNA
CTD
PMID:19647056 PMID:21404309
NCBI chr11:83,463,743...83,469,462
Ensembl chr11:83,463,745...83,469,462
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Ccna2
cyclin A2
affects expression increases expression
EXP
Dinitrochlorobenzene affects the expression of CCNA2 mRNA Dinitrochlorobenzene results in increased expression of CCNA2 mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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Ccnb1
cyclin B1
affects expression
EXP
Dinitrochlorobenzene affects the expression of CCNB1 mRNA
CTD
PMID:22302311
NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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Ccnb2
cyclin B2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCNB2 mRNA
CTD
PMID:21404309
NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829
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Ccne1
cyclin E1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCNE1 mRNA
CTD
PMID:21404309
NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
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Ccne2
cyclin E2
affects expression
EXP
Dinitrochlorobenzene affects the expression of CCNE2 mRNA
CTD
PMID:22302311
NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
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Ccnf
cyclin F
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCNF mRNA
CTD
PMID:18242016
NCBI chr17:24,441,518...24,470,333
Ensembl chr17:24,441,172...24,470,458
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Ccr1
C-C motif chemokine receptor 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CCR1 mRNA
CTD
PMID:19647056
NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
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Ccr2
C-C motif chemokine receptor 2
increases expression decreases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CCR2 mRNA Dinitrochlorobenzene results in decreased expression of CCR2 mRNA
CTD
PMID:17374397 PMID:19371601 PMID:19647056 PMID:20713136
NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
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Ccr3
C-C motif chemokine receptor 3
multiple interactions increases expression
EXP
Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCR3 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCR3 mRNA]
CTD
PMID:23133493
NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
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Ccr4
C-C motif chemokine receptor 4
affects expression
EXP
Dinitrochlorobenzene affects the expression of CCR4 mRNA
CTD
PMID:22302311
NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984
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Ccr5
C-C motif chemokine receptor 5
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCR5 mRNA
CTD
PMID:20713136
NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
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Ccr6
C-C motif chemokine receptor 6
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of CCR6 mRNA
CTD
PMID:21404309
NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
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Ccr7
C-C motif chemokine receptor 7
increases expression multiple interactions decreases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CCR7 mRNA Dinitrochlorobenzene results in increased expression of CCR7 mRNA; Dinitrochlorobenzene results in increased expression of CCR7 protein TNF protein affects the reaction [Dinitrochlorobenzene results in increased expression of CCR7 mRNA] Dinitrochlorobenzene results in decreased expression of CCR7 mRNA
CTD
PMID:15304089 PMID:15737199 PMID:17374397 PMID:19159591 PMID:19371601 PMID:20713136 PMID:28219650 More...
NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903
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Cct3
chaperonin containing TCP1 subunit 3
affects binding
ISO
Dinitrochlorobenzene binds to CCT3 protein
CTD
PMID:32991956
NCBI chr 3:88,204,442...88,229,073
Ensembl chr 3:88,204,423...88,229,074
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Cct4
chaperonin containing TCP1 subunit 4
affects binding
ISO
Dinitrochlorobenzene binds to CCT4 protein
CTD
PMID:32991956
NCBI chr11:22,940,593...22,953,336
Ensembl chr11:22,940,519...22,953,780
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Cct5
chaperonin containing TCP1 subunit 5
affects binding
ISO
Dinitrochlorobenzene binds to CCT5 protein
CTD
PMID:32991956
NCBI chr15:31,590,946...31,601,992
Ensembl chr15:31,590,946...31,601,950
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Cd109
CD109 antigen
affects binding increases expression
ISO
Dinitrochlorobenzene binds to CD109 protein Dinitrochlorobenzene results in increased expression of CD109 protein
CTD
PMID:32991956 PMID:33774146
NCBI chr 9:78,522,828...78,623,542
Ensembl chr 9:78,522,828...78,623,535
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Cd160
CD160 antigen
affects expression
EXP
Dinitrochlorobenzene affects the expression of CD160 mRNA
CTD
PMID:22302311
NCBI chr 3:96,706,079...96,736,667
Ensembl chr 3:96,706,079...96,736,667
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Cd207
CD207 antigen
affects expression
EXP
Dinitrochlorobenzene affects the expression of CD207 mRNA
CTD
PMID:22302311
NCBI chr 6:83,648,189...83,654,839
Ensembl chr 6:83,648,197...83,654,839
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Cd274
CD274 antigen
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CD274 mRNA; Dinitrochlorobenzene results in increased expression of CD274 protein
CTD
PMID:20488241 PMID:28941582
NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
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Cd36
CD36 molecule
decreases expression
ISO EXP
Dinitrochlorobenzene results in decreased expression of CD36 mRNA
CTD
PMID:17374397 PMID:21404309
NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
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Cd40
CD40 antigen
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CD40 protein
CTD
PMID:17636246 PMID:21742781
NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
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Cd5l
CD5 antigen-like
affects expression
EXP
Dinitrochlorobenzene affects the expression of CD5L mRNA
CTD
PMID:22302311
NCBI chr 3:87,265,188...87,278,381
Ensembl chr 3:87,265,188...87,278,380
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Cd80
CD80 antigen
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CD80 mRNA
CTD
PMID:28219650
NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
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Cd83
CD83 antigen
affects expression increases expression decreases expression
EXP ISO
Dinitrochlorobenzene affects the expression of CD83 mRNA Dinitrochlorobenzene results in increased expression of CD83 mRNA; Dinitrochlorobenzene results in increased expression of CD83 protein Dinitrochlorobenzene results in decreased expression of CD83 mRNA
CTD
PMID:17636246 PMID:22302311 PMID:28219650 PMID:28941582
NCBI chr13:43,938,661...43,956,608
Ensembl chr13:43,938,251...43,956,608
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Cd86
CD86 antigen
increases expression multiple interactions affects expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CD86 mRNA; Dinitrochlorobenzene results in increased expression of CD86 protein Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of CD86 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; bisindolylmaleimide I inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; cariporide inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Citric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Cysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Glutathione inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Lactic Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein] Dinitrochlorobenzene affects the expression of CD86 mRNA
CTD
PMID:12423654 PMID:15737199 PMID:17374397 PMID:17636246 PMID:19033392 PMID:19665512 PMID:20417223 PMID:20457211 PMID:20488241 PMID:21742781 PMID:24136171 PMID:28219650 PMID:28389280 PMID:29743441 PMID:30842373 PMID:33774146 More...
NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
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Cdc20
cell division cycle 20
affects expression increases expression
EXP
Dinitrochlorobenzene affects the expression of CDC20 mRNA Dinitrochlorobenzene results in increased expression of CDC20 mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
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Cdc25c
cell division cycle 25C
affects expression increases expression
EXP
Dinitrochlorobenzene affects the expression of CDC25C mRNA Dinitrochlorobenzene results in increased expression of CDC25C mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586
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Cdc45
cell division cycle 45
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CDC45 mRNA
CTD
PMID:21404309
NCBI chr16:18,599,202...18,632,371
Ensembl chr16:18,599,197...18,630,737
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Cdc5l
cell division cycle 5-like
affects binding
ISO
Dinitrochlorobenzene binds to CDC5L protein
CTD
PMID:32991956
NCBI chr17:45,702,809...45,744,633
Ensembl chr17:45,702,810...45,744,663
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Cdc6
cell division cycle 6
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CDC6 mRNA
CTD
PMID:21404309
NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
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Cdca2
cell division cycle associated 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CDCA2 mRNA
CTD
PMID:18242016
NCBI chr14:67,910,629...67,953,290
Ensembl chr14:67,913,780...67,953,290
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Cdh8
cadherin 8
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CDH8 mRNA
CTD
PMID:17374397
NCBI chr 8:99,751,103...100,144,298
Ensembl chr 8:99,751,103...100,143,103
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Cdk1
cyclin dependent kinase 1
affects expression increases expression
EXP
Dinitrochlorobenzene affects the expression of CDK1 mRNA Dinitrochlorobenzene results in increased expression of CDK1 mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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Cdk12
cyclin dependent kinase 12
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CDK12 mRNA
CTD
PMID:25236440
NCBI chr11:98,093,259...98,171,941
Ensembl chr11:98,093,885...98,169,330
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Cdkn1a
cyclin dependent kinase inhibitor 1A
increases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CDKN1A mRNA
CTD
PMID:16314067 PMID:21404309
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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Cdkn1c
cyclin dependent kinase inhibitor 1C
increases expression decreases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CDKN1C mRNA Dinitrochlorobenzene results in decreased expression of CDKN1C mRNA
CTD
PMID:20146380 PMID:21404309
NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787
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Cebpz
CCAAT/enhancer binding protein zeta
affects binding
ISO
Dinitrochlorobenzene binds to CEBPZ protein
CTD
PMID:32991956
NCBI chr17:79,226,432...79,244,499
Ensembl chr17:79,226,435...79,244,495
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Celf1
CUGBP, Elav-like family member 1
affects binding
ISO
Dinitrochlorobenzene binds to CELF1 protein
CTD
PMID:32991956
NCBI chr 2:90,770,604...90,849,842
Ensembl chr 2:90,770,727...90,849,842
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Cerkl
ceramide kinase-like
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CERKL mRNA
CTD
PMID:17374397
NCBI chr 2:79,162,835...79,259,332
Ensembl chr 2:79,160,887...79,287,129
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Ces1d
carboxylesterase 1D
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CES1 mRNA
CTD
PMID:19524605
NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
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Cfap91
cilia and flagella associated protein 91
affects binding
ISO
Dinitrochlorobenzene binds to MAATS1 protein
CTD
PMID:32991956
NCBI chr16:38,118,116...38,162,222
Ensembl chr16:38,118,116...38,162,505
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Chd3
chromodomain helicase DNA binding protein 3
affects binding
ISO
Dinitrochlorobenzene binds to CHD3 protein
CTD
PMID:32991956
NCBI chr11:69,234,099...69,260,325
Ensembl chr11:69,234,099...69,260,232
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Chd4
chromodomain helicase DNA binding protein 4
affects binding
ISO
Dinitrochlorobenzene binds to CHD4 protein
CTD
PMID:32991956
NCBI chr 6:125,073,144...125,107,554
Ensembl chr 6:125,072,944...125,107,554
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Chd5
chromodomain helicase DNA binding protein 5
affects binding
ISO
Dinitrochlorobenzene binds to CHD5 protein
CTD
PMID:32991956
NCBI chr 4:152,423,103...152,474,651
Ensembl chr 4:152,423,108...152,474,651
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Chid1
chitinase domain containing 1
affects binding
ISO
Dinitrochlorobenzene binds to CHID1 protein
CTD
PMID:32991956
NCBI chr 7:141,073,049...141,119,818
Ensembl chr 7:141,073,049...141,119,770
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Cidec
cell death-inducing DFFA-like effector c
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CIDEC mRNA
CTD
PMID:17374397
NCBI chr 6:113,401,595...113,412,721
Ensembl chr 6:113,401,595...113,412,721
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Cisd1
CDGSH iron sulfur domain 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CISD1 mRNA
CTD
PMID:17374397
NCBI chr10:71,166,324...71,180,679
Ensembl chr10:71,166,310...71,180,784
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Clasp1
CLIP associating protein 1
affects binding
ISO
Dinitrochlorobenzene binds to CLASP1 protein
CTD
PMID:32991956
NCBI chr 1:118,314,976...118,537,192
Ensembl chr 1:118,316,788...118,540,408
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Clec5a
C-type lectin domain family 5, member a
increases expression affects expression
ISO
Dinitrochlorobenzene results in increased expression of CLEC5A protein Dinitrochlorobenzene affects the expression of CLEC5A mRNA
CTD
PMID:33774146
NCBI chr 6:40,551,832...40,562,739
Ensembl chr 6:40,551,828...40,562,755
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Clic1
chloride intracellular channel 1
affects binding
ISO
Dinitrochlorobenzene binds to CLIC1 protein
CTD
PMID:32991956
NCBI chr17:35,269,219...35,277,695
Ensembl chr17:35,268,942...35,277,725
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Clic4
chloride intracellular channel 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CLIC4 mRNA
CTD
PMID:16314067
NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125
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Cln8
CLN8 transmembrane ER and ERGIC protein
affects binding
ISO
Dinitrochlorobenzene binds to CLN8 protein
CTD
PMID:32991956
NCBI chr 8:14,931,335...14,951,720
Ensembl chr 8:14,931,335...14,951,720
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Cmpk2
cytidine/uridine monophosphate kinase 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CMPK2 mRNA
CTD
PMID:17374397
NCBI chr12:26,519,121...26,529,836
Ensembl chr12:26,519,203...26,529,836
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Cnn3
calponin 3, acidic
affects binding
ISO
Dinitrochlorobenzene binds to CNN3 protein
CTD
PMID:32991956
NCBI chr 3:121,220,190...121,251,854
Ensembl chr 3:121,220,146...121,251,856
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Cnot1
CCR4-NOT transcription complex, subunit 1
affects binding
ISO
Dinitrochlorobenzene binds to CNOT1 protein
CTD
PMID:32991956
NCBI chr 8:96,445,559...96,534,741
Ensembl chr 8:96,446,079...96,534,092
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Cnot9
CCR4-NOT transcription complex, subunit 9
affects binding
ISO
Dinitrochlorobenzene binds to CNOT9 protein
CTD
PMID:32991956
NCBI chr 1:74,545,192...74,570,001
Ensembl chr 1:74,545,217...74,570,001
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Cog4
component of oligomeric golgi complex 4
affects binding
ISO
Dinitrochlorobenzene binds to COG4 protein
CTD
PMID:32991956
NCBI chr 8:111,573,232...111,608,866
Ensembl chr 8:111,573,232...111,608,859
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Commd3
COMM domain containing 3
increases expression
EXP
Dinitrochlorobenzene results in increased expression of COMMD3 mRNA
CTD
PMID:21404309
NCBI chr 2:18,677,246...18,681,042
Ensembl chr 2:18,677,234...18,681,042
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Cope
coatomer protein complex, subunit epsilon
affects binding
ISO
Dinitrochlorobenzene binds to COPE protein
CTD
PMID:32991956
NCBI chr 8:70,755,417...70,765,652
Ensembl chr 8:70,755,168...70,765,643
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Cox4i1
cytochrome c oxidase subunit 4I1
affects binding
ISO
Dinitrochlorobenzene binds to COX4I1 protein
CTD
PMID:32991956
NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946
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Cphx1
cytoplasmic polyadenylated homeobox 1
affects expression
EXP
Dinitrochlorobenzene affects the expression of CPHX1 mRNA
CTD
PMID:22302311
NCBI chr14:25,941,983...25,956,798
Ensembl chr14:25,938,728...25,956,780
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Cpne3
copine III
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CPNE3 mRNA
CTD
PMID:17374397
NCBI chr 4:19,519,252...19,570,108
Ensembl chr 4:19,519,254...19,570,108
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Creb1
cAMP responsive element binding protein 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of CREB1 mRNA
CTD
PMID:20385217
NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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Crem
cAMP responsive element modulator
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CREM mRNA
CTD
PMID:17374397 PMID:19371601
NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
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Crkl
v-crk avian sarcoma virus CT10 oncogene homolog-like
affects binding
ISO
Dinitrochlorobenzene binds to CRKL protein
CTD
PMID:32991956
NCBI chr16:17,269,849...17,305,304
Ensembl chr16:17,269,851...17,305,298
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Crocc
ciliary rootlet coiled-coil, rootletin
affects binding
ISO
Dinitrochlorobenzene binds to CROCC protein
CTD
PMID:32991956
NCBI chr 4:140,743,948...140,787,927
Ensembl chr 4:140,743,948...140,787,861
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Csf2
colony stimulating factor 2 (granulocyte-macrophage)
increases expression increases secretion
EXP
Dinitrochlorobenzene results in increased expression of CSF2 mRNA Dinitrochlorobenzene results in increased secretion of CSF2 protein
CTD
PMID:18652873 PMID:22245253
NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
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Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CSF2RA mRNA
CTD
PMID:19647056
NCBI chr19:61,205,629...61,221,141
Ensembl chr19:61,212,395...61,216,867
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Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CSF2RB mRNA; Dinitrochlorobenzene results in increased expression of CSF2RB2 mRNA
CTD
PMID:19647056
NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921
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Csf3
colony stimulating factor 3 (granulocyte)
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CSF3 mRNA
CTD
PMID:18652873
NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
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Csf3r
colony stimulating factor 3 receptor
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CSF3R mRNA
CTD
PMID:19647056
NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233
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Ctla4
cytotoxic T-lymphocyte-associated protein 4
affects expression
EXP
Dinitrochlorobenzene affects the expression of CTLA4 mRNA
CTD
PMID:22302311
NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
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Ctnna1
catenin alpha 1
affects binding
ISO
Dinitrochlorobenzene binds to CTNNA1 protein
CTD
PMID:32991956
NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
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Ctnna2
catenin alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to CTNNA2 protein
CTD
PMID:32991956
NCBI chr 6:76,858,620...77,956,798
Ensembl chr 6:76,858,620...77,956,682
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Ctnnbl1
catenin, beta like 1
affects binding
ISO
Dinitrochlorobenzene binds to CTNNBL1 protein
CTD
PMID:32991956
NCBI chr 2:157,579,321...157,733,823
Ensembl chr 2:157,579,321...157,733,534
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Ctps2
cytidine 5'-triphosphate synthase 2
affects binding
ISO
Dinitrochlorobenzene binds to CTPS2 protein
CTD
PMID:32991956
NCBI chr X:161,684,264...161,817,537
Ensembl chr X:161,684,234...161,815,504
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Ctsb
cathepsin B
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of CTSB mRNA Dinitrochlorobenzene binds to CTSB protein
CTD
PMID:16314067 PMID:32991956
NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
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Ctsc
cathepsin C
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CTSC mRNA
CTD
PMID:17374397
NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096
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Ctsl
cathepsin L
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CTSL mRNA
CTD
PMID:17374397
NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
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Cul1
cullin 1
affects binding
ISO
Dinitrochlorobenzene binds to CUL1 protein
CTD
PMID:32991956
NCBI chr 6:47,430,516...47,503,078
Ensembl chr 6:47,430,332...47,503,073
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Cul4a
cullin 4A
affects binding
ISO
Dinitrochlorobenzene binds to CUL4A protein
CTD
PMID:32991956
NCBI chr 8:13,155,623...13,197,940
Ensembl chr 8:13,155,621...13,197,940
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Cxcl1
C-X-C motif chemokine ligand 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCL1 mRNA
CTD
PMID:20146380 PMID:20713136
NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
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Cxcl10
C-X-C motif chemokine ligand 10
increases expression multiple interactions affects expression
EXP ISO
Dinitrochlorobenzene results in increased expression of CXCL10 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL10 mRNA] Dinitrochlorobenzene affects the expression of CXCL10 mRNA
CTD
PMID:19647056 PMID:20146380 PMID:21404309 PMID:28219650
NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
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Cxcl14
C-X-C motif chemokine ligand 14
increases expression decreases expression
EXP ISO
Dinitrochlorobenzene results in increased expression of CXCL14 mRNA Dinitrochlorobenzene results in decreased expression of CXCL14 protein
CTD
PMID:19647056 PMID:31734321
NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
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Cxcl15
C-X-C motif chemokine ligand 15
multiple interactions increases stability increases expression increases secretion
ISO
[Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of CXCL8 protein; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased secretion of CXCL8 protein]; bisindolylmaleimide I affects the reaction [Dinitrochlorobenzene results in increased expression of CXCL8 protein]; Glutathione inhibits the reaction [Dinitrochlorobenzene results in increased secretion of CXCL8 protein]; KN 62 inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL8 mRNA]; SB 203580 affects the reaction [Dinitrochlorobenzene results in increased secretion of CXCL8 protein]; SB 203580 inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL8 mRNA] Dinitrochlorobenzene results in increased stability of CXCL8 mRNA Dinitrochlorobenzene results in increased expression of CXCL8 mRNA; Dinitrochlorobenzene results in increased expression of CXCL8 protein
CTD
PMID:12781210 PMID:16099135 PMID:17118622 PMID:17636246 PMID:18494145 PMID:18495191 PMID:19427879 PMID:19878716 PMID:20417223 PMID:20457211 PMID:20491607 PMID:20713136 PMID:21920952 PMID:21969073 PMID:24136171 PMID:24964617 PMID:25290854 PMID:25617811 PMID:27965148 PMID:28389280 PMID:28941582 PMID:31734321 More...
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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Cxcl16
C-X-C motif chemokine ligand 16
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of CXCL16 mRNA
CTD
PMID:21404309
NCBI chr11:70,345,215...70,350,810
Ensembl chr11:70,344,809...70,350,810
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of CXCL2 mRNA Dinitrochlorobenzene results in increased expression of CXCL2 mRNA; Dinitrochlorobenzene results in increased expression of CXCL2 protein
CTD
PMID:16675337 PMID:19647056 PMID:20146380 PMID:23178550 PMID:28826779
NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
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Cxcl3
C-X-C motif chemokine ligand 3
increases expression multiple interactions
ISO EXP
Dinitrochlorobenzene results in increased expression of CXCL1 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL1 mRNA]
CTD
PMID:19647056 PMID:20146380 PMID:20713136 PMID:21404309 PMID:28219650 PMID:28826779 More...
NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
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Cxcl5
C-X-C motif chemokine ligand 5
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CXCL5 mRNA
CTD
PMID:19647056
NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483
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Cxcl9
C-X-C motif chemokine ligand 9
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CXCL9 mRNA
CTD
PMID:21404309
NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
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Cxcr1
C-X-C motif chemokine receptor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCR1 protein
CTD
PMID:33774146
NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790
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Cxcr2
C-X-C motif chemokine receptor 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of CXCR2 mRNA
CTD
PMID:19647056
NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
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Cxcr3
C-X-C motif chemokine receptor 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCR3 protein
CTD
PMID:33774146
NCBI chr X:100,775,141...100,777,753
Ensembl chr X:100,775,141...100,777,875
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression increases expression
ISO EXP
Dinitrochlorobenzene results in decreased expression of CXCR4 mRNA Dinitrochlorobenzene results in increased expression of CXCR4 mRNA
CTD
PMID:17374397 PMID:19371601 PMID:19647056 PMID:20146380 PMID:28219650
NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
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Cxcr6
C-X-C motif chemokine receptor 6
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of CXCR6 mRNA
CTD
PMID:21404309
NCBI chr 9:123,635,542...123,640,819
Ensembl chr 9:123,635,540...123,640,825
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CYP1A1 mRNA
CTD
PMID:20491607
NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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Cytip
cytohesin 1 interacting protein
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CYTIP mRNA
CTD
PMID:17374397 PMID:19371601
NCBI chr 2:58,019,151...58,085,559
Ensembl chr 2:58,019,149...58,085,544
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D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of FERRY3 mRNA
CTD
PMID:17374397
NCBI chr 6:126,916,938...126,952,667
Ensembl chr 6:126,916,925...126,952,930
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Dact1
dishevelled-binding antagonist of beta-catenin 1
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of DACT1 mRNA
CTD
PMID:18242016
NCBI chr12:71,356,658...71,366,881
Ensembl chr12:71,356,658...71,366,881
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Dap3
death associated protein 3
affects binding
ISO
Dinitrochlorobenzene binds to DAP3 protein
CTD
PMID:32991956
NCBI chr 3:88,828,110...88,858,504
Ensembl chr 3:88,828,110...88,858,488
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Dcps
decapping enzyme, scavenger
affects binding
ISO
Dinitrochlorobenzene binds to DCPS protein
CTD
PMID:32991956
NCBI chr 9:35,035,710...35,087,283
Ensembl chr 9:35,035,704...35,087,357
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Dctpp1
dCTP pyrophosphatase 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DCTPP1 mRNA
CTD
PMID:17374397
NCBI chr 7:126,856,131...126,859,839
Ensembl chr 7:126,856,131...126,859,881
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Ddit3
DNA-damage inducible transcript 3
multiple interactions increases expression
ISO
Glutathione inhibits the reaction [Dinitrochlorobenzene results in increased expression of DDIT3 mRNA]
CTD
PMID:17171638
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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Ddx1
DEAD box helicase 1
affects binding
ISO
Dinitrochlorobenzene binds to DDX1 protein
CTD
PMID:32991956
NCBI chr12:13,269,308...13,299,175
Ensembl chr12:13,266,974...13,299,214
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Ddx18
DEAD box helicase 18
affects binding
ISO
Dinitrochlorobenzene binds to DDX18 protein
CTD
PMID:32991956
NCBI chr 1:121,481,564...121,495,709
Ensembl chr 1:121,481,564...121,495,718
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Ddx52
DExD box helicase 52
affects binding
ISO
Dinitrochlorobenzene binds to DDX52 protein
CTD
PMID:32991956
NCBI chr11:83,831,659...83,853,914
Ensembl chr11:83,832,888...83,853,914
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Ddx56
DEAD box helicase 56
affects binding
ISO
Dinitrochlorobenzene binds to DDX56 protein
CTD
PMID:32991956
NCBI chr11:6,205,343...6,218,389
Ensembl chr11:6,208,919...6,217,772
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Dhps
deoxyhypusine synthase
affects binding
ISO
Dinitrochlorobenzene binds to DHPS protein
CTD
PMID:32991956
NCBI chr 8:85,798,106...85,801,790
Ensembl chr 8:85,798,386...85,801,791
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Dhx36
DEAH-box helicase 36
affects binding
ISO
Dinitrochlorobenzene binds to DHX36 protein
CTD
PMID:32991956
NCBI chr 3:62,375,436...62,414,464
Ensembl chr 3:62,375,434...62,414,425
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Dhx9
DExH-box helicase 9
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of DHX9 protein Dinitrochlorobenzene binds to DHX9 protein
CTD
PMID:29267982 PMID:32991956
NCBI chr 1:153,331,506...153,363,464
Ensembl chr 1:153,331,504...153,363,406
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Diaph1
diaphanous related formin 1
affects binding
ISO
Dinitrochlorobenzene binds to DIAPH1 protein
CTD
PMID:32991956
NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529
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Dkc1
dyskeratosis congenita 1, dyskerin
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DKC1 mRNA
CTD
PMID:17374397
NCBI chr X:74,139,460...74,153,382
Ensembl chr X:74,139,460...74,153,383
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Dld
dihydrolipoamide dehydrogenase
affects binding
ISO
Dinitrochlorobenzene binds to DLD protein
CTD
PMID:32991956
NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452
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Dlgap5
DLG associated protein 5
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DLGAP5 mRNA
CTD
PMID:17374397
NCBI chr14:47,625,238...47,655,657
Ensembl chr14:47,625,236...47,655,864
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Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA]
CTD
PMID:23999411 PMID:27965148
NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
G
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of DNAJB6 mRNA
CTD
PMID:17374397
NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132
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Dnmt1
DNA methyltransferase 1
affects binding
ISO
Dinitrochlorobenzene binds to DNMT1 protein
CTD
PMID:32991956
NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
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Dnmt3b
DNA methyltransferase 3B
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DNMT3B mRNA
CTD
PMID:25236440
NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
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Dock5
dedicator of cytokinesis 5
affects binding
ISO
Dinitrochlorobenzene binds to DOCK5 protein
CTD
PMID:32991956
NCBI chr14:67,989,377...68,171,021
Ensembl chr14:67,989,584...68,170,891
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Dpyd
dihydropyrimidine dehydrogenase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DPYD mRNA
CTD
PMID:17374397
NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573
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Dpysl2
dihydropyrimidinase-like 2
affects binding
ISO
Dinitrochlorobenzene binds to DPYSL2 protein
CTD
PMID:32991956
NCBI chr14:67,040,313...67,148,490
Ensembl chr14:67,040,313...67,148,410
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Dse
dermatan sulfate epimerase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DSE mRNA
CTD
PMID:17374397
NCBI chr10:34,027,385...34,084,267
Ensembl chr10:34,027,389...34,083,711
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Dtymk
deoxythymidylate kinase
increases expression
EXP
Dinitrochlorobenzene results in increased expression of DTYMK mRNA
CTD
PMID:21404309
NCBI chr 1:93,720,298...93,730,246
Ensembl chr 1:93,720,298...93,729,656
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Dusp1
dual specificity phosphatase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of DUSP1 mRNA
CTD
PMID:16314067
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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Dusp3
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
affects binding
ISO
Dinitrochlorobenzene binds to DUSP3 protein
CTD
PMID:32991956
NCBI chr11:101,861,967...101,877,839
Ensembl chr11:101,861,969...101,877,839
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Dusp4
dual specificity phosphatase 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of DUSP4 mRNA
CTD
PMID:18242016
NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048
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Dut
deoxyuridine triphosphatase
increases expression
EXP
Dinitrochlorobenzene results in increased expression of DUT mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr 2:125,089,168...125,100,969
Ensembl chr 2:125,089,110...125,100,528
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E2f1
E2F transcription factor 1
affects expression
EXP
Dinitrochlorobenzene affects the expression of E2F1 mRNA
CTD
PMID:22302311
NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
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Ear2
eosinophil-associated, ribonuclease A family, member 2
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of EAR2 mRNA
CTD
PMID:18242016
NCBI chr14:44,340,111...44,340,988
Ensembl chr14:44,340,111...44,340,991
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Ecd
ecdysoneless cell cycle regulator
affects binding
ISO
Dinitrochlorobenzene binds to ECD protein
CTD
PMID:32991956
NCBI chr14:20,369,927...20,398,189
Ensembl chr14:20,369,920...20,398,189
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Ecpas
Ecm29 proteasome adaptor and scaffold
affects binding
ISO
Dinitrochlorobenzene binds to ECPAS protein
CTD
PMID:32991956
NCBI chr 4:58,797,234...58,917,748
Ensembl chr 4:58,798,911...58,912,749
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Eef1a2
eukaryotic translation elongation factor 1 alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to EEF1A2 protein
CTD
PMID:32991956
NCBI chr 2:180,783,551...180,798,808
Ensembl chr 2:180,789,446...180,798,807
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Egf
epidermal growth factor
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of EGF mRNA
CTD
PMID:20146380
NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
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Egfr
epidermal growth factor receptor
affects binding
ISO
Dinitrochlorobenzene binds to EGFR protein
CTD
PMID:32991956
NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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Egr2
early growth response 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of EGR2 mRNA
CTD
PMID:17374397
NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
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Ehhadh
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of EHHADH mRNA
CTD
PMID:17374397
NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557
G
Eif3a
eukaryotic translation initiation factor 3, subunit A
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of EIF3A protein
CTD
PMID:29267982
NCBI chr19:60,749,554...60,779,131
Ensembl chr19:60,749,555...60,779,096
G
Eif3g
eukaryotic translation initiation factor 3, subunit G
affects binding
ISO
Dinitrochlorobenzene binds to EIF3G protein
CTD
PMID:32991956
NCBI chr 9:20,805,645...20,809,886
Ensembl chr 9:20,805,645...20,809,919
G
Eif4b
eukaryotic translation initiation factor 4B
affects binding
ISO
Dinitrochlorobenzene binds to EIF4B protein
CTD
PMID:32991956
NCBI chr15:101,982,208...102,005,608
Ensembl chr15:101,982,208...102,005,608
G
Eif4g3
eukaryotic translation initiation factor 4 gamma, 3
affects binding
ISO
Dinitrochlorobenzene binds to EIF4G3 protein
CTD
PMID:32991956
NCBI chr 4:137,719,090...137,934,397
Ensembl chr 4:137,720,333...137,935,819
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Elac2
elaC ribonuclease Z 2
affects binding
ISO
Dinitrochlorobenzene binds to ELAC2 protein
CTD
PMID:32991956
NCBI chr11:64,869,856...64,892,906
Ensembl chr11:64,869,864...64,892,895
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Elavl1
ELAV like RNA binding protein 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ELAVL1 protein
CTD
PMID:21969073
NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413
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Elmod2
ELMO/CED-12 domain containing 2
affects binding
ISO
Dinitrochlorobenzene binds to ELMOD2 protein
CTD
PMID:32991956
NCBI chr 8:84,039,261...84,059,115
Ensembl chr 8:84,039,261...84,059,115
G
Emb
embigin
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of EMB mRNA
CTD
PMID:17374397
NCBI chr13:117,357,109...117,410,951
Ensembl chr13:117,345,072...117,410,951
G
Emd
emerin
affects expression
ISO
Dinitrochlorobenzene affects the expression of EMD mRNA
CTD
PMID:19527780
NCBI chr X:73,298,297...73,305,188
Ensembl chr X:73,298,293...73,305,154
G
Epor
erythropoietin receptor
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of EPOR mRNA
CTD
PMID:21404309
NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
G
Eprs1
glutamyl-prolyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to EPRS1 protein
CTD
PMID:32991956
NCBI chr 1:185,093,614...185,160,557
Ensembl chr 1:185,095,241...185,160,557
G
Ercc6
excision repair cross-complementing rodent repair deficiency, complementation group 6
affects binding
ISO
Dinitrochlorobenzene binds to ERCC6 protein
CTD
PMID:32991956
NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947
G
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ERCC6L mRNA
CTD
PMID:18242016
NCBI chr X:101,186,426...101,200,697
Ensembl chr X:101,185,322...101,200,697
G
Esd
esterase D/formylglutathione hydrolase
affects binding
ISO
Dinitrochlorobenzene binds to ESD protein
CTD
PMID:32991956
NCBI chr14:74,969,591...74,988,205
Ensembl chr14:74,969,737...74,988,205
G
Esr1
estrogen receptor 1 (alpha)
affects expression
ISO
Dinitrochlorobenzene affects the expression of ESR1 mRNA
CTD
PMID:19527780
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
G
Esyt2
extended synaptotagmin-like protein 2
affects binding
ISO
Dinitrochlorobenzene binds to ESYT2 protein
CTD
PMID:32991956
NCBI chr12:116,242,903...116,354,555
Ensembl chr12:116,244,816...116,354,670
G
Evpl
envoplakin
affects binding
ISO
Dinitrochlorobenzene binds to EVPL protein
CTD
PMID:32991956
NCBI chr11:116,111,385...116,128,983
Ensembl chr11:116,111,385...116,128,903
G
Exoc1
exocyst complex component 1
affects binding
ISO
Dinitrochlorobenzene binds to EXOC1 protein
CTD
PMID:32991956
NCBI chr 5:76,677,147...76,718,134
Ensembl chr 5:76,677,158...76,718,141
G
Exoc6b
exocyst complex component 6B
affects binding
ISO
Dinitrochlorobenzene binds to EXOC6B protein
CTD
PMID:32991956
NCBI chr 6:84,595,468...85,046,524
Ensembl chr 6:84,595,469...85,046,495
G
Ezr
ezrin
affects binding
ISO
Dinitrochlorobenzene binds to EZR protein
CTD
PMID:32991956
NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
G
F13a1
coagulation factor XIII, A1 subunit
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of F13A1 mRNA
CTD
PMID:17374397
NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
G
Fabp1
fatty acid binding protein 1, liver
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of FABP1 mRNA
CTD
PMID:18242016
NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
G
Fabp7
fatty acid binding protein 7, brain
affects expression
EXP
Dinitrochlorobenzene affects the expression of FABP7 mRNA
CTD
PMID:22302311
NCBI chr10:57,661,019...57,664,546
Ensembl chr10:57,660,977...57,664,546
G
Fam3c
FAM3 metabolism regulating signaling molecule C
affects binding
ISO
Dinitrochlorobenzene binds to FAM3C protein
CTD
PMID:32991956
NCBI chr 6:22,306,519...22,356,080
Ensembl chr 6:22,306,519...22,356,242
G
Fam76b
family with sequence similarity 76, member B
affects binding
ISO
Dinitrochlorobenzene binds to FAM76B protein
CTD
PMID:32991956
NCBI chr 9:13,738,490...13,766,033
Ensembl chr 9:13,739,012...13,766,283
G
Farsa
phenylalanyl-tRNA synthetase, alpha subunit
affects binding
ISO
Dinitrochlorobenzene binds to FARSA protein
CTD
PMID:32991956
NCBI chr 8:85,583,597...85,595,886
Ensembl chr 8:85,583,618...85,595,886
G
Fasn
fatty acid synthase
affects binding
ISO
Dinitrochlorobenzene binds to FASN protein
CTD
PMID:32991956
NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
G
Fbxo9
f-box protein 9
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of FBXO9 mRNA
CTD
PMID:17374397
NCBI chr 9:77,988,781...78,016,347
Ensembl chr 9:77,988,781...78,016,347
G
Fech
ferrochelatase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FECH mRNA
CTD
PMID:20566472
NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322
G
Ffar2
free fatty acid receptor 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of FFAR2 mRNA
CTD
PMID:18242016
NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200
G
Fgf9
fibroblast growth factor 9
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FGF9 mRNA
CTD
PMID:20146380
NCBI chr14:58,308,543...58,350,311
Ensembl chr14:58,308,004...58,350,177
G
Fgfr3
fibroblast growth factor receptor 3
affects binding
ISO
Dinitrochlorobenzene binds to FGFR3 protein
CTD
PMID:32991956
NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
G
Fgl2
fibrinogen-like protein 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of FGL2 mRNA
CTD
PMID:17374397
NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372
G
Fkbp8
FK506 binding protein 8
affects binding
ISO
Dinitrochlorobenzene binds to FKBP8 protein
CTD
PMID:32991956
NCBI chr 8:70,980,371...70,987,978
Ensembl chr 8:70,980,374...70,987,978
G
Flna
filamin, alpha
affects binding
ISO
Dinitrochlorobenzene binds to FLNA protein
CTD
PMID:32991956
NCBI chr X:73,267,067...73,293,787
Ensembl chr X:73,267,067...73,293,426
G
Flnb
filamin, beta
affects binding
ISO
Dinitrochlorobenzene binds to FLNB protein
CTD
PMID:32991956
NCBI chr14:14,518,185...14,651,852
Ensembl chr14:14,518,185...14,651,816
G
Fos
FBJ osteosarcoma oncogene
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FOS mRNA
CTD
PMID:20146380 PMID:25236440
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
G
Fosl1
fos-like antigen 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FOSL1 mRNA
CTD
PMID:25236440
NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
G
Fosl2
fos-like antigen 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FOSL2 mRNA
CTD
PMID:17374397
NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
G
Frmd7
FERM domain containing 7
affects binding
ISO
Dinitrochlorobenzene binds to FRMD7 protein
CTD
PMID:32991956
NCBI chr X:49,980,044...50,032,493
Ensembl chr X:49,984,057...50,031,587
G
Fscn1
fascin actin-bundling protein 1
affects binding
ISO
Dinitrochlorobenzene binds to FSCN1 protein
CTD
PMID:32991956
NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940
G
Fth1
ferritin heavy polypeptide 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FTH1 mRNA
CTD
PMID:16314067
NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
G
Ftl1
ferritin light polypeptide 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FTL mRNA
CTD
PMID:20566472
NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
G
Fxyd4
FXYD domain-containing ion transport regulator 4
affects expression
EXP
Dinitrochlorobenzene affects the expression of FXYD4 mRNA
CTD
PMID:22302311
NCBI chr 6:117,910,519...117,914,668
Ensembl chr 6:117,910,520...117,914,653
G
G6pdx
glucose-6-phosphate dehydrogenase X-linked
increases expression
ISO
Dinitrochlorobenzene results in increased expression of G6PD mRNA
CTD
PMID:20566472
NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800
G
Gal3st1
galactose-3-O-sulfotransferase 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of GAL3ST1 mRNA
CTD
PMID:19527780
NCBI chr11:3,933,636...3,949,328
Ensembl chr11:3,933,636...3,949,326
G
Gars1
glycyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to GARS1 protein
CTD
PMID:32991956
NCBI chr 6:55,014,986...55,056,489
Ensembl chr 6:55,014,992...55,056,485
G
Gart
phosphoribosylglycinamide formyltransferase
affects binding
ISO
Dinitrochlorobenzene binds to GART protein
CTD
PMID:32991956
NCBI chr16:91,418,283...91,444,505
Ensembl chr16:91,418,074...91,443,840
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GCLC mRNA
CTD
PMID:20146380 PMID:20566472
NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
G
Gclm
glutamate-cysteine ligase, modifier subunit
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of GCLM mRNA NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA]
CTD
PMID:20146380 PMID:20566472 PMID:23999411 PMID:27965148
NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
G
Gdi2
GDP dissociation inhibitor 2
affects binding
ISO
Dinitrochlorobenzene binds to GDI2 protein
CTD
PMID:32991956
NCBI chr13:3,588,075...3,616,261
Ensembl chr13:3,588,063...3,617,871
G
Glyr1
glyoxylate reductase 1 homolog (Arabidopsis)
affects binding
ISO
Dinitrochlorobenzene binds to GLYR1 protein
CTD
PMID:32991956
NCBI chr16:4,831,766...4,867,780
Ensembl chr16:4,831,773...4,867,727
G
Gmpr
guanosine monophosphate reductase
increases methylation
EXP
Dinitrochlorobenzene results in increased methylation of GMPR gene
CTD
PMID:26732893
NCBI chr13:45,660,905...45,699,862
Ensembl chr13:45,660,920...45,707,276
G
Gmps
guanine monophosphate synthetase
affects binding
ISO
Dinitrochlorobenzene binds to GMPS protein
CTD
PMID:32991956
NCBI chr 3:63,871,054...63,928,975
Ensembl chr 3:63,883,527...63,930,000
G
Golga2
golgin A2
affects binding
ISO
Dinitrochlorobenzene binds to GOLGA2 protein
CTD
PMID:32991956
NCBI chr 2:32,178,299...32,197,925
Ensembl chr 2:32,177,396...32,197,933
G
Golgb1
golgin B1
affects binding
ISO
Dinitrochlorobenzene binds to GOLGB1 protein
CTD
PMID:32991956
NCBI chr16:36,695,455...36,753,447
Ensembl chr16:36,695,502...36,753,447
G
Gon4l
gon-4 like
affects binding
ISO
Dinitrochlorobenzene binds to GON4L protein
CTD
PMID:32991956
NCBI chr 3:88,742,531...88,817,406
Ensembl chr 3:88,742,535...88,817,410
G
Gpat3
glycerol-3-phosphate acyltransferase 3
affects expression
ISO
Dinitrochlorobenzene affects the expression of GPAT3 mRNA
CTD
PMID:33774146
NCBI chr 5:100,994,095...101,046,968
Ensembl chr 5:100,993,579...101,046,968
G
Gpd2
glycerol phosphate dehydrogenase 2, mitochondrial
affects binding
ISO
Dinitrochlorobenzene binds to GPD2 protein
CTD
PMID:32991956
NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
G
Gpi1
glucose-6-phosphate isomerase 1
affects binding
ISO
Dinitrochlorobenzene binds to GPI protein
CTD
PMID:32991956
NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761
G
Gpnmb
glycoprotein (transmembrane) nmb
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GPNMB mRNA
CTD
PMID:16314067
NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
G
Gpx1
glutathione peroxidase 1
multiple interactions affects expression
EXP
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX1 mRNA] Dinitrochlorobenzene affects the expression of GPX1 mRNA
CTD
PMID:28219650
NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
G
Gpx2
glutathione peroxidase 2
multiple interactions affects expression
EXP
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX2 mRNA] Dinitrochlorobenzene affects the expression of GPX2 mRNA
CTD
PMID:28219650
NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GPX3 mRNA
CTD
PMID:20566472
NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
G
Gpx5
glutathione peroxidase 5
multiple interactions affects expression
EXP
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX5 mRNA] Dinitrochlorobenzene affects the expression of GPX5 mRNA
CTD
PMID:28219650
NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901
G
Gpx6
glutathione peroxidase 6
affects expression multiple interactions
EXP
Dinitrochlorobenzene affects the expression of GPX6 mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX6 mRNA]
CTD
PMID:28219650
NCBI chr13:21,479,635...21,503,795
Ensembl chr13:21,496,295...21,503,794
G
Gpx7
glutathione peroxidase 7
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of GPX7 mRNA
CTD
PMID:28219650
NCBI chr 4:108,257,414...108,263,910
Ensembl chr 4:108,257,587...108,264,158
G
Grap2
GRB2-related adaptor protein 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of GRAP2 mRNA
CTD
PMID:21404309
NCBI chr15:80,456,798...80,537,055
Ensembl chr15:80,456,795...80,537,055
G
Grem1
gremlin 1, DAN family BMP antagonist
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GREM1 mRNA
CTD
PMID:20146380
NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991
G
Grsf1
G-rich RNA sequence binding factor 1
affects binding
ISO
Dinitrochlorobenzene binds to GRSF1 protein
CTD
PMID:32991956
NCBI chr 5:88,807,092...88,824,030
Ensembl chr 5:88,807,307...88,824,030
G
Gsk3b
glycogen synthase kinase 3 beta
increases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of GSK3B mRNA
CTD
PMID:17374397 PMID:28219650
NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
G
Gsr
glutathione reductase
increases expression multiple interactions
ISO EXP
Dinitrochlorobenzene results in increased expression of GSR mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GSR mRNA]
CTD
PMID:20566472 PMID:28219650
NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
G
Gsta3
glutathione S-transferase, alpha 3
affects binding increases glutathionylation
EXP
Dinitrochlorobenzene binds to GSTA3 protein GSTA3 protein results in increased glutathionylation of Dinitrochlorobenzene
CTD
PMID:8910329 PMID:21876218
NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885
G
Gsta4
glutathione S-transferase, alpha 4
affects metabolic processing affects binding
ISO
GSTA4 protein affects the metabolism of Dinitrochlorobenzene 1-chloro-2 4-dinitrobenzene binds to Gsta4 protein
CTD RGD
PMID:2619714 PMID:11018474
RGD:1641942
NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631
G
Gstm1
glutathione S-transferase, mu 1
affects metabolic processing affects binding multiple interactions affects expression increases glutathionylation decreases expression
ISO EXP
GSTM1 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene binds to GSTM1 protein GSTM1 protein affects the metabolism of Dinitrochlorobenzene; GSTM5 protein affects the metabolism of Dinitrochlorobenzene GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog] Dinitrochlorobenzene affects the expression of GSTM1 mRNA GSTM1 protein results in increased glutathionylation of Dinitrochlorobenzene Dinitrochlorobenzene results in decreased expression of GSTM1 mRNA
CTD
PMID:2904809 PMID:3570286 PMID:9545290 PMID:12069689 PMID:21404309 PMID:22085405 PMID:28219650 PMID:28762043 More...
NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
G
Gstm2
glutathione S-transferase, mu 2
affects metabolic processing multiple interactions affects activity increases expression
ISO
GSTM2 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene promotes the reaction [GSTM2 protein affects the metabolism of Glutathione] Dinitrochlorobenzene affects the activity of GSTM2 protein Dinitrochlorobenzene results in increased expression of GSTM2 protein
CTD
PMID:3570286 PMID:9794801
NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
G
Gstm4
glutathione S-transferase, mu 4
multiple interactions affects metabolic processing
ISO
GSTM4 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione] GSTM4 protein affects the metabolism of Dinitrochlorobenzene
CTD
PMID:8203914 PMID:8349586
NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210
G
Gstm5
glutathione S-transferase, mu 5
increases metabolic processing decreases metabolic processing affects metabolic processing increases expression decreases expression
ISO EXP
GSTM3 protein polymorphism results in increased metabolism of Dinitrochlorobenzene GSTM3 protein polymorphism results in decreased metabolism of Dinitrochlorobenzene GSTM3 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTM3 protein Dinitrochlorobenzene results in decreased expression of GSTM3 mRNA
CTD
PMID:3169012 PMID:9545290 PMID:9794801 PMID:15247628 PMID:21404309
NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
G
Gstp1
glutathione S-transferase, pi 1
affects metabolic processing multiple interactions increases expression decreases activity affects binding decreases response to substance increases activity
ISO
GSTP1 protein affects the metabolism of Dinitrochlorobenzene; GSTP2 protein affects the metabolism of Dinitrochlorobenzene GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene; Mercuric Chloride inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene]; methylmercuric chloride inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene]; Sodium Selenite inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene] Dinitrochlorobenzene results in increased expression of GSTP1 protein Dinitrochlorobenzene results in decreased activity of GSTP1 protein 1-chloro-2,4-dinitrobenzene binds to Gstp1 protein GSTP1 protein mutant form results in decreased susceptibility to Dinitrochlorobenzene Dinitrochlorobenzene results in increased activity of GSTP1 protein mutant form
CTD RGD
PMID:2619714 PMID:3570286 PMID:9794801 PMID:10870112 PMID:15355982 PMID:22401947 PMID:37031912 PMID:11018474 More...
RGD:1641942
NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
G
Gstt1
glutathione S-transferase, theta 1
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of GSTT1 mRNA
CTD
PMID:28219650
NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
G
Gstz1
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
affects metabolic processing
ISO
GSTZ1 protein affects the metabolism of Dinitrochlorobenzene
CTD
PMID:1846734
NCBI chr12:87,192,102...87,211,497
Ensembl chr12:87,193,939...87,211,497
G
Gtf2b
general transcription factor IIB
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GTF2B mRNA
CTD
PMID:17374397
NCBI chr 3:142,471,008...142,489,367
Ensembl chr 3:142,470,806...142,489,367
G
Gtf2i
general transcription factor II I
affects binding
ISO
Dinitrochlorobenzene binds to GTF2I protein
CTD
PMID:32991956
NCBI chr 5:134,266,686...134,346,571
Ensembl chr 5:134,266,688...134,343,614
G
Gyg1
glycogenin 1
affects binding
ISO
Dinitrochlorobenzene binds to GYG1 protein
CTD
PMID:32991956
NCBI chr 3:20,176,248...20,209,228
Ensembl chr 3:20,176,248...20,209,481
G
Gzma
granzyme A
increases expression
EXP
Dinitrochlorobenzene results in increased expression of GZMA mRNA
CTD
PMID:18242016
NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515
G
Gzmb
granzyme B
increases expression affects expression
EXP ISO
Dinitrochlorobenzene results in increased expression of GZMB mRNA Dinitrochlorobenzene affects the expression of GZMB mRNA
CTD
PMID:18652873 PMID:21893156 PMID:22302311
NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
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H3f3c
H3 histone, family 3C
affects binding
ISO
Dinitrochlorobenzene binds to H3F3C protein
CTD
PMID:32991956
NCBI chr 2:119,495,597...119,496,633
Ensembl chr 2:119,496,107...119,496,517
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H4c1
H4 clustered histone 1
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of H4C1 protein
CTD
PMID:29267982
NCBI chr13:23,944,778...23,945,232
Ensembl chr13:23,944,675...23,945,213
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Hadha
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to HADHA protein
CTD
PMID:32991956
NCBI chr 5:30,324,421...30,359,978
Ensembl chr 5:30,323,302...30,360,160
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Has1
hyaluronan synthase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HAS1 mRNA; Dinitrochlorobenzene results in increased expression of HAS1 protein
CTD
PMID:31226360
NCBI chr17:18,063,588...18,075,450
Ensembl chr17:18,063,585...18,075,467
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Has2
hyaluronan synthase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HAS2 mRNA; Dinitrochlorobenzene results in increased expression of HAS2 protein
CTD
PMID:31226360
NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935
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Has3
hyaluronan synthase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HAS3 mRNA; Dinitrochlorobenzene results in increased expression of HAS3 protein
CTD
PMID:31226360
NCBI chr 8:107,596,874...107,609,534
Ensembl chr 8:107,596,874...107,611,198
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Hbb-b1
hemoglobin, beta adult major chain
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of HBB protein
CTD
PMID:29267982
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Hdlbp
high density lipoprotein (HDL) binding protein
affects binding
ISO
Dinitrochlorobenzene binds to HDLBP protein
CTD
PMID:32991956
NCBI chr 1:93,333,662...93,406,639
Ensembl chr 1:93,333,662...93,406,537
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Heatr1
HEAT repeat containing 1
affects binding
ISO
Dinitrochlorobenzene binds to HEATR1 protein
CTD
PMID:32991956
NCBI chr13:12,410,256...12,453,774
Ensembl chr13:12,409,908...12,455,170
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Heatr5b
HEAT repeat containing 5B
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of HEATR5B mRNA
CTD
PMID:17374397
NCBI chr17:79,060,335...79,142,810
Ensembl chr17:79,060,327...79,142,793
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Hebp2
heme binding protein 2
affects binding
ISO
Dinitrochlorobenzene binds to HEBP2 protein
CTD
PMID:32991956
NCBI chr10:18,415,871...18,421,824
Ensembl chr10:18,415,246...18,421,824
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Hectd4
HECT domain E3 ubiquitin protein ligase 4
affects binding
ISO
Dinitrochlorobenzene binds to HECTD4 protein
CTD
PMID:32991956
NCBI chr 5:121,357,323...121,506,633
Ensembl chr 5:121,358,282...121,506,640
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Hexa
hexosaminidase A
affects binding
ISO
Dinitrochlorobenzene binds to HEXA protein
CTD
PMID:32991956
NCBI chr 9:59,446,966...59,472,392
Ensembl chr 9:59,446,823...59,472,392
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Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HIPK2 mRNA
CTD
PMID:16314067
NCBI chr 6:38,664,447...38,853,236
Ensembl chr 6:38,671,325...38,853,099
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Hmgb1
high mobility group box 1
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of HMGB1 mRNA
CTD
PMID:28219650
NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
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Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO EXP
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; BACH1 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]
CTD
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20566472 PMID:20713136 PMID:25236440 PMID:26244607 PMID:28219650 PMID:31967339 More...
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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Hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of HNRNPA3 mRNA
CTD
PMID:17374397
NCBI chr 2:75,489,416...75,499,751
Ensembl chr 2:75,489,605...75,499,751
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Hnrnpc
heterogeneous nuclear ribonucleoprotein C
affects binding
ISO
Dinitrochlorobenzene binds to HNRNPC protein
CTD
PMID:32991956
NCBI chr14:52,310,834...52,341,462
Ensembl chr14:52,310,834...52,341,485
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Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
increases expression
EXP
Dinitrochlorobenzene results in increased expression of HNRNPLL mRNA
CTD
PMID:21404309
NCBI chr17:80,336,916...80,369,697
Ensembl chr17:80,336,916...80,369,697
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Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects binding
ISO
Dinitrochlorobenzene binds to HSD17B4 protein
CTD
PMID:32991956
NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
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Hspa1a
heat shock protein 1A
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of HSPA1A protein
CTD
PMID:29267982
NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
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Hspa2
heat shock protein 2
affects binding
ISO
Dinitrochlorobenzene binds to HSPA2 protein
CTD
PMID:32991956
NCBI chr12:76,450,688...76,453,712
Ensembl chr12:76,450,950...76,453,712
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Hspa8
heat shock protein 8
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of HSPA8 protein Dinitrochlorobenzene binds to HSPA8 protein
CTD
PMID:29267982 PMID:32991956
NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
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Hspb1
heat shock protein 1
affects binding
ISO
Dinitrochlorobenzene binds to HSPB1 protein
CTD
PMID:32991956
NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
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Hspd1
heat shock protein 1 (chaperonin)
affects binding
ISO
Dinitrochlorobenzene binds to HSPD1 protein
CTD
PMID:32991956
NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
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Hsph1
heat shock 105kDa/110kDa protein 1
affects binding
ISO
Dinitrochlorobenzene binds to HSPH1 protein
CTD
PMID:32991956
NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841
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Hyal1
hyaluronoglucosaminidase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HYAL1 mRNA
CTD
PMID:31226360
NCBI chr 9:107,454,149...107,458,898
Ensembl chr 9:107,454,126...107,458,909
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Iars1
isoleucyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to IARS1 protein
CTD
PMID:32991956
NCBI chr13:49,835,606...49,887,743
Ensembl chr13:49,835,576...49,887,743
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Icam1
intercellular adhesion molecule 1
increases expression multiple interactions affects expression
ISO
Dinitrochlorobenzene results in increased expression of ICAM1 mRNA; Dinitrochlorobenzene results in increased expression of ICAM1 protein Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]; cariporide inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Citric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Lactic Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Potassium Chloride affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]
CTD
PMID:15737199 PMID:19427879 PMID:20417223 PMID:21742781 PMID:29743441 PMID:30842373 PMID:33774146 More...
NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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Id2
inhibitor of DNA binding 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ID2 mRNA
CTD
PMID:20146380
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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Ide
insulin degrading enzyme
affects binding
ISO
Dinitrochlorobenzene binds to IDE protein
CTD
PMID:32991956
NCBI chr19:37,246,140...37,341,664
Ensembl chr19:37,246,142...37,340,010
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Idi1
isopentenyl-diphosphate delta isomerase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of IDI1 mRNA
CTD
PMID:17374397
NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
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Ier3
immediate early response 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IER3 mRNA
CTD
PMID:17374397
NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
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Ifi27
interferon, alpha-inducible protein 27
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IFI27 mRNA
CTD
PMID:18242016
NCBI chr12:103,400,448...103,406,504
Ensembl chr12:103,400,470...103,406,498
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Ifi44l
interferon-induced protein 44 like
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IFI44L mRNA
CTD
PMID:18242016
NCBI chr 3:151,464,374...151,468,528
Ensembl chr 3:151,464,374...151,468,529
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Ifit1
interferon-induced protein with tetratricopeptide repeats 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IFIT1 mRNA
CTD
PMID:19647056
NCBI chr19:34,618,289...34,627,409
Ensembl chr19:34,618,271...34,627,409
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Ifit2
interferon-induced protein with tetratricopeptide repeats 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of IFIT2 mRNA
CTD
PMID:17374397
NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819
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Ifng
interferon gamma
multiple interactions increases secretion increases expression decreases expression
EXP ISO
4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein]; [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA; [Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein] Dinitrochlorobenzene results in increased secretion of IFNG protein Dinitrochlorobenzene results in increased expression of IFNG mRNA; Dinitrochlorobenzene results in increased expression of IFNG protein Dinitrochlorobenzene results in decreased expression of IFNG mRNA
CTD
PMID:10637130 PMID:11708898 PMID:12202904 PMID:12884401 PMID:15588915 PMID:15588918 PMID:18242016 PMID:18652873 PMID:19042193 PMID:19422874 PMID:21404309 PMID:22245253 PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868 PMID:25449201 PMID:28219650 PMID:29233007 PMID:30017638 More...
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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Ifrd1
interferon-related developmental regulator 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IFRD1 mRNA
CTD
PMID:17374397
NCBI chr12:40,253,128...40,273,184
Ensembl chr12:40,251,566...40,298,503
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Igbp1
immunoglobulin (CD79A) binding protein 1
affects binding
ISO
Dinitrochlorobenzene binds to IGBP1 protein
CTD
PMID:32991956
NCBI chr X:99,537,897...99,559,731
Ensembl chr X:99,537,897...99,559,731
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Igfbp6
insulin-like growth factor binding protein 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IGFBP6 mRNA
CTD
PMID:17374397
NCBI chr15:102,052,621...102,057,947
Ensembl chr15:102,052,797...102,057,946
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Il10
interleukin 10
increases expression multiple interactions affects expression decreases expression
EXP
Dinitrochlorobenzene results in increased expression of IL10 protein [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL10 mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL10 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 protein] Dinitrochlorobenzene affects the expression of IL10 mRNA Dinitrochlorobenzene results in decreased expression of IL10 mRNA; Dinitrochlorobenzene results in decreased expression of IL10 protein
CTD
PMID:19422874 PMID:23499868 PMID:28219650 PMID:29233007 PMID:34651546
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Il10ra
interleukin 10 receptor, alpha
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL10RA mRNA
CTD
PMID:19647056
NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
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Il11
interleukin 11
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL11 mRNA
CTD
PMID:19647056
NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858
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Il12a
interleukin 12a
increases expression decreases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of IL12A mRNA Dinitrochlorobenzene results in decreased expression of IL12A mRNA
CTD
PMID:25449201 PMID:28219650
NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
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Il12b
interleukin 12b
increases expression increases secretion affects expression decreases methylation increases methylation
EXP ISO
Dinitrochlorobenzene results in increased expression of IL12B mRNA; Dinitrochlorobenzene results in increased expression of IL12B protein Dinitrochlorobenzene results in increased secretion of IL12B protein Dinitrochlorobenzene affects the expression of IL12B mRNA Dinitrochlorobenzene results in decreased methylation of IL12B gene Dinitrochlorobenzene results in increased methylation of IL12B gene
CTD
PMID:10199581 PMID:11708898 PMID:18652873 PMID:22302311 PMID:25449201 PMID:26732893 PMID:28219650 More...
NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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Il12rb1
interleukin 12 receptor, beta 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL12RB1 mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr 8:71,261,005...71,276,186
Ensembl chr 8:71,261,093...71,274,068
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Il13
interleukin 13
multiple interactions increases expression
EXP
Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 protein] Dinitrochlorobenzene results in increased expression of IL13 mRNA; Dinitrochlorobenzene results in increased expression of IL13 protein
CTD
PMID:23133493 PMID:23200891 PMID:23454147 PMID:29233007
NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
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Il17a
interleukin 17A
multiple interactions increases expression
EXP ISO
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL17A mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL17A mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL17A mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL17A mRNA]
CTD
PMID:23133493 PMID:23499868 PMID:25449201
NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
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Il18
interleukin 18
increases activity increases expression multiple interactions
EXP ISO
Dinitrochlorobenzene results in increased activity of IL18 protein Dinitrochlorobenzene results in increased expression of IL18 mRNA Dinitrochlorobenzene results in increased expression of IL18 protein PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein]
CTD
PMID:11708898 PMID:15840424 PMID:23063874 PMID:27585668 PMID:28389280
NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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Il18r1
interleukin 18 receptor 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL18R1 mRNA
CTD
PMID:11708898
NCBI chr 1:40,504,712...40,540,014
Ensembl chr 1:40,504,712...40,540,014
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Il19
interleukin 19
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL19 mRNA
CTD
PMID:19647056
NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852
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Il1a
interleukin 1 alpha
increases activity increases expression multiple interactions affects secretion affects expression
EXP ISO
Dinitrochlorobenzene results in increased activity of IL1A protein Dinitrochlorobenzene results in increased expression of IL1A mRNA; Dinitrochlorobenzene results in increased expression of IL1A protein Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] Dinitrochlorobenzene affects the secretion of IL1A protein Dinitrochlorobenzene affects the expression of IL1A mRNA
CTD
PMID:7476933 PMID:12781210 PMID:15840424 PMID:18652873 PMID:23178550 PMID:28219650 PMID:33715048 More...
NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
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Il1b
interleukin 1 beta
increases expression multiple interactions increases secretion affects expression
ISO EXP
Dinitrochlorobenzene results in increased expression of IL1B mRNA; Dinitrochlorobenzene results in increased expression of IL1B protein Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA] Dinitrochlorobenzene results in increased secretion of IL1B protein Dinitrochlorobenzene affects the expression of IL1B mRNA [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL1B protein
CTD
PMID:11033066 PMID:16314067 PMID:16687389 PMID:18652873 PMID:19647056 PMID:20146380 PMID:21404309 PMID:24964617 PMID:28219650 PMID:28941582 PMID:30842373 PMID:33715048 PMID:33774146 More...
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il1rl1
interleukin 1 receptor-like 1
increases expression
EXP ISO
Dinitrochlorobenzene results in increased expression of IL1RL1 mRNA
CTD
PMID:11708898 PMID:20146380
NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
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Il2
interleukin 2
increases expression increases secretion
EXP
Dinitrochlorobenzene results in increased expression of IL2 mRNA; Dinitrochlorobenzene results in increased expression of IL2 protein Dinitrochlorobenzene results in increased secretion of IL2 protein
CTD
PMID:15588918 PMID:18652873 PMID:22245253 PMID:22381623
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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Il21
interleukin 21
affects expression
EXP
Dinitrochlorobenzene affects the expression of IL21 mRNA
CTD
PMID:22302311
NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785
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Il22b
interleukin 22B
multiple interactions
EXP
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL22 mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL22 mRNA]
CTD
PMID:23499868
NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943
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Il23a
interleukin 23, alpha subunit p19
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL23A mRNA
CTD
PMID:25449201
NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
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Il24
interleukin 24
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL24 mRNA
CTD
PMID:19647056
NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
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Il25
interleukin 25
increases methylation
EXP
Dinitrochlorobenzene results in increased methylation of IL25 gene; Dinitrochlorobenzene results in increased methylation of IL25 promoter
CTD
PMID:24675093 PMID:26732893
NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294
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Il2ra
interleukin 2 receptor, alpha chain
affects expression increases expression
EXP
Dinitrochlorobenzene affects the expression of IL2RA mRNA Dinitrochlorobenzene results in increased expression of IL2RA mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
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Il3
interleukin 3
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL3 mRNA
CTD
PMID:18652873
NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
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Il31
interleukin 31
multiple interactions
EXP
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL31 mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL31 mRNA]
CTD
PMID:23499868
NCBI chr 5:123,618,215...123,620,686
Ensembl chr 5:123,618,220...123,627,552
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Il4
interleukin 4
affects expression multiple interactions increases expression decreases expression
EXP
Dinitrochlorobenzene affects the expression of IL4 mRNA [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL4 mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL4 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 protein] Dinitrochlorobenzene results in increased expression of IL4 mRNA; Dinitrochlorobenzene results in increased expression of IL4 protein Dinitrochlorobenzene results in decreased expression of IL4 mRNA; Dinitrochlorobenzene results in decreased expression of IL4 protein
CTD
PMID:15588918 PMID:15664275 PMID:18652873 PMID:19422874 PMID:22302311 PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868 PMID:28826779 PMID:29233007 PMID:34651546 More...
NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
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Il4ra
interleukin 4 receptor, alpha
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL4RA mRNA; Dinitrochlorobenzene results in increased expression of IL4RA protein
CTD
PMID:19647056 PMID:22381623
NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
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Il5
interleukin 5
multiple interactions increases expression
EXP
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]
CTD
PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868
NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
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Il6
interleukin 6
multiple interactions increases expression increases secretion
EXP ISO
[Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of IL6 mRNA; Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of IL6 mRNA] Dinitrochlorobenzene results in increased expression of IL6 mRNA; Dinitrochlorobenzene results in increased expression of IL6 protein Dinitrochlorobenzene results in increased secretion of IL6 protein [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL6 protein
CTD
PMID:11378323 PMID:12202904 PMID:16687389 PMID:18652873 PMID:19647056 PMID:22245253 PMID:24964617 PMID:28941582 More...
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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Il7
interleukin 7
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of IL7 mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820
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Il7r
interleukin 7 receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL7R mRNA
CTD
PMID:20713136
NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262
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Ilf3
interleukin enhancer binding factor 3
affects binding
ISO
Dinitrochlorobenzene binds to ILF3 protein
CTD
PMID:32991956
NCBI chr 9:21,278,964...21,316,659
Ensembl chr 9:21,279,167...21,316,657
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Inhba
inhibin beta-A
increases expression
EXP
Dinitrochlorobenzene results in increased expression of INHBA mRNA
CTD
PMID:19647056
NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
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Ipcef1
interaction protein for cytohesin exchange factors 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of IPCEF1 mRNA
CTD
PMID:17374397
NCBI chr10:6,835,779...6,973,185
Ensembl chr10:6,835,796...7,002,478
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Ipo7
importin 7
affects binding
ISO
Dinitrochlorobenzene binds to IPO7 protein
CTD
PMID:32991956
NCBI chr 7:109,617,522...109,655,816
Ensembl chr 7:109,617,481...109,655,816
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Ipo8
importin 8
affects binding
ISO
Dinitrochlorobenzene binds to IPO8 protein
CTD
PMID:32991956
NCBI chr 6:148,672,181...148,732,977
Ensembl chr 6:148,672,181...148,732,965
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Ipo9
importin 9
affects binding
ISO
Dinitrochlorobenzene binds to IPO9 protein
CTD
PMID:32991956
NCBI chr 1:135,310,050...135,358,260
Ensembl chr 1:135,310,050...135,358,237
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Iqgap1
IQ motif containing GTPase activating protein 1
affects binding
ISO
Dinitrochlorobenzene binds to IQGAP1 protein
CTD
PMID:32991956
NCBI chr 7:80,361,331...80,453,288
Ensembl chr 7:80,361,331...80,475,722
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Iqgap2
IQ motif containing GTPase activating protein 2
affects binding
ISO
Dinitrochlorobenzene binds to IQGAP2 protein
CTD
PMID:32991956
NCBI chr13:95,763,685...96,028,788
Ensembl chr13:95,763,682...96,028,991
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Irf1
interferon regulatory factor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IRF1 mRNA
CTD
PMID:20146380
NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
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Itgav
integrin alpha V
affects expression
EXP
Dinitrochlorobenzene affects the expression of ITGAV mRNA
CTD
PMID:22302311
NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
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Ivl
involucrin
affects binding
ISO
Dinitrochlorobenzene binds to IVL protein
CTD
PMID:32991956
NCBI chr 3:92,478,206...92,481,097
Ensembl chr 3:92,478,209...92,481,042
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Jun
jun proto-oncogene
increases expression
ISO
Dinitrochlorobenzene results in increased expression of JUN mRNA
CTD
PMID:16314067
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of KCNJ2 mRNA
CTD
PMID:17374397
NCBI chr11:110,956,990...110,967,651
Ensembl chr11:110,956,990...110,967,647
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Keap1
kelch-like ECH-associated protein 1
multiple interactions affects metabolic processing increases expression decreases expression
ISO EXP
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein]; Dinitrochlorobenzene promotes the reaction [KEAP1 protein binds to KEAP1 protein]; tetrachlorobenzoquinone promotes the reaction [Dinitrochlorobenzene promotes the reaction [KEAP1 protein binds to KEAP1 protein]] Dinitrochlorobenzene affects the metabolism of KEAP1 protein Dinitrochlorobenzene results in decreased expression of KEAP1 mRNA
CTD
PMID:18785192 PMID:19033392 PMID:25742418 PMID:28219650
NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
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Kif23
kinesin family member 23
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of KIF23 mRNA
CTD
PMID:17374397
NCBI chr 9:61,824,559...61,854,078
Ensembl chr 9:61,823,187...61,854,056
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Kifc1
kinesin family member C1
affects binding
ISO
Dinitrochlorobenzene binds to KIFC1 protein
CTD
PMID:32991956
NCBI chr17:34,094,640...34,109,607
Ensembl chr17:34,094,633...34,109,635
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Kitl
kit ligand
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of KITL mRNA
CTD
PMID:21404309
NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
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Klf6
Kruppel-like transcription factor 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of KLF6 mRNA
CTD
PMID:16314067 PMID:17374397
NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
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Kpna2
karyopherin subunit alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to KPNA2 protein
CTD
PMID:32991956
NCBI chr11:106,879,455...106,890,351
Ensembl chr11:106,879,455...106,890,367
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Krr1
KRR1, small subunit (SSU) processome component, homolog (yeast)
affects binding
ISO
Dinitrochlorobenzene binds to KRR1 protein
CTD
PMID:32991956
NCBI chr10:111,808,600...111,824,335
Ensembl chr10:111,808,569...111,824,337
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Krt14
keratin 14
affects binding
ISO
Dinitrochlorobenzene binds to KRT14 protein
CTD
PMID:32991956
NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374
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Krt16
keratin 16
affects binding
ISO
Dinitrochlorobenzene binds to KRT16 protein
CTD
PMID:32991956
NCBI chr11:100,136,917...100,139,728
Ensembl chr11:100,136,917...100,139,728
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Krt17
keratin 17
affects binding
ISO
Dinitrochlorobenzene binds to KRT17 protein
CTD
PMID:32991956
NCBI chr11:100,147,041...100,151,855
Ensembl chr11:100,147,043...100,151,855
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Krt2
keratin 2
affects binding
ISO
Dinitrochlorobenzene binds to KRT2 protein
CTD
PMID:32991956
NCBI chr15:101,719,124...101,727,391
Ensembl chr15:101,719,124...101,726,604
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Krt4
keratin 4
affects binding
ISO
Dinitrochlorobenzene binds to KRT4 protein
CTD
PMID:32991956
NCBI chr15:101,826,970...101,833,170
Ensembl chr15:101,826,970...101,833,170
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Krt5
keratin 5
affects binding
ISO
Dinitrochlorobenzene binds to KRT5 protein
CTD
PMID:32991956
NCBI chr15:101,615,504...101,621,340
Ensembl chr15:101,615,505...101,621,333
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Krt6a
keratin 6A
increases methylation affects binding
EXP ISO
Dinitrochlorobenzene results in increased methylation of KRT6A promoter Dinitrochlorobenzene binds to KRT6A protein
CTD
PMID:24675093 PMID:32991956
NCBI chr15:101,598,363...101,602,746
Ensembl chr15:101,598,345...101,602,742
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Krt6b
keratin 6B
affects binding
ISO
Dinitrochlorobenzene binds to KRT6B protein
CTD
PMID:32991956
NCBI chr15:101,584,458...101,588,728
Ensembl chr15:101,584,458...101,588,722
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Krt73
keratin 73
affects binding
ISO
Dinitrochlorobenzene binds to KRT73 protein
CTD
PMID:32991956
NCBI chr15:101,701,739...101,710,795
Ensembl chr15:101,701,743...101,710,781
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Krt74
keratin 74
affects binding
ISO
Dinitrochlorobenzene binds to KRT74 protein
CTD
PMID:32991956
NCBI chr15:101,662,694...101,671,939
Ensembl chr15:101,662,787...101,671,873 Ensembl chr15:101,662,787...101,671,873
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Krt75
keratin 75
affects binding
ISO
Dinitrochlorobenzene binds to KRT75 protein
CTD
PMID:32991956
NCBI chr15:101,471,778...101,482,339
Ensembl chr15:101,471,780...101,482,339
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Krt76
keratin 76
affects binding
ISO
Dinitrochlorobenzene binds to KRT76 protein
CTD
PMID:32991956
NCBI chr15:101,792,786...101,801,355
Ensembl chr15:101,792,786...101,801,355
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Krt78
keratin 78
affects binding
ISO
Dinitrochlorobenzene binds to KRT78 protein
CTD
PMID:32991956
NCBI chr15:101,854,436...101,905,059
Ensembl chr15:101,854,436...101,862,722
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Lamp2
lysosomal-associated membrane protein 2
affects binding
ISO
Dinitrochlorobenzene binds to LAMP2 protein
CTD
PMID:32991956
NCBI chr X:37,488,524...37,545,337
Ensembl chr X:37,490,234...37,545,331
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Lgals7
lectin, galactose binding, soluble 7
affects expression
EXP
Dinitrochlorobenzene affects the expression of LGALS7 mRNA
CTD
PMID:22302311
NCBI chr 7:28,563,258...28,565,711
Ensembl chr 7:28,563,278...28,565,709
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Lig1
ligase I, DNA, ATP-dependent
increases expression
EXP
Dinitrochlorobenzene results in increased expression of LIG1 mRNA
CTD
PMID:21404309
NCBI chr 7:13,011,101...13,045,351
Ensembl chr 7:13,011,239...13,045,350
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Lmna
lamin A
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of LMNA protein Dinitrochlorobenzene binds to LMNA protein
CTD
PMID:29267982 PMID:32991956
NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263
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Lmnb2
lamin B2
affects binding
ISO
Dinitrochlorobenzene binds to LMNB2 protein
CTD
PMID:32991956
NCBI chr10:80,737,197...80,754,079
Ensembl chr10:80,737,037...80,754,079
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Ltb
lymphotoxin B
increases expression
EXP
Dinitrochlorobenzene results in increased expression of LTB mRNA
CTD
PMID:19647056
NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296
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Ly6i
lymphocyte antigen 6 family member I
increases expression
EXP
Dinitrochlorobenzene results in increased expression of LY6I mRNA
CTD
PMID:18242016
NCBI chr15:74,851,383...74,855,279
Ensembl chr15:74,851,383...74,855,279
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Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MAFF mRNA
CTD
PMID:20491607 PMID:20566472
NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
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Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MAFG mRNA
CTD
PMID:20566472
NCBI chr11:120,515,943...120,525,771
Ensembl chr11:120,515,943...120,524,426
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Mafk
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MAFK mRNA
CTD
PMID:17374397 PMID:20566472
NCBI chr 5:139,777,291...139,788,409
Ensembl chr 5:139,777,268...139,788,408
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Magef1
MAGE family member F1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MAGEF1 mRNA
CTD
PMID:17374397
NCBI chr16:21,150,650...21,152,106
Ensembl chr16:21,151,396...21,151,879 Ensembl chr16:21,151,396...21,151,879
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Maip1
matrix AAA peptidase interacting protein 1
affects binding
ISO
Dinitrochlorobenzene binds to MAIP1 protein
CTD
PMID:32991956
NCBI chr 1:57,445,425...57,457,112
Ensembl chr 1:57,445,487...57,457,112
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Map2k2
mitogen-activated protein kinase kinase 2
affects binding
ISO
Dinitrochlorobenzene binds to MAP2K2 protein
CTD
PMID:32991956
NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
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Map3k1
mitogen-activated protein kinase kinase kinase 1
affects binding
ISO
Dinitrochlorobenzene binds to MAP3K1 protein
CTD
PMID:32991956
NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527
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Mapk1
mitogen-activated protein kinase 1
multiple interactions decreases phosphorylation
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein]; SB 203580 inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein]
CTD
PMID:18495191
NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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Mapk12
mitogen-activated protein kinase 12
decreases methylation
EXP
Dinitrochlorobenzene results in decreased methylation of MAPK12 promoter
CTD
PMID:24675093
NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906
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Mapk14
mitogen-activated protein kinase 14
increases phosphorylation affects binding
ISO
Dinitrochlorobenzene results in increased phosphorylation of MAPK14 protein Dinitrochlorobenzene binds to MAPK14 protein
CTD
PMID:15737199 PMID:32991956
NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
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Mapk3
mitogen-activated protein kinase 3
multiple interactions decreases phosphorylation
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein]; SB 203580 inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein]
CTD
PMID:18495191
NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
ISO
Dinitrochlorobenzene results in increased phosphorylation of MAPK8 protein
CTD
PMID:18495191
NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
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Marcks
myristoylated alanine rich protein kinase C substrate
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MARCKS mRNA
CTD
PMID:16314067
NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916
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Mccc2
methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
affects binding
ISO
Dinitrochlorobenzene binds to MCCC2 protein
CTD
PMID:32991956
NCBI chr13:100,085,040...100,152,147
Ensembl chr13:100,085,038...100,152,147
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Mcf2
mcf.2 transforming sequence
affects binding
ISO
Dinitrochlorobenzene binds to MCF2 protein
CTD
PMID:32991956
NCBI chr X:59,101,316...59,224,546
Ensembl chr X:59,101,316...59,224,449
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Mcf2l
mcf.2 transforming sequence-like
affects binding
ISO
Dinitrochlorobenzene binds to MCF2L protein
CTD
PMID:32991956
NCBI chr 8:12,923,806...13,070,502
Ensembl chr 8:12,923,806...13,070,905
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Mcm2
minichromosome maintenance complex component 2
increases expression affects binding
EXP ISO
Dinitrochlorobenzene results in increased expression of MCM2 mRNA Dinitrochlorobenzene binds to MCM2 protein
CTD
PMID:21404309 PMID:32991956
NCBI chr 6:88,860,456...88,875,762
Ensembl chr 6:88,860,456...88,875,762
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Mcm3
minichromosome maintenance complex component 3
increases expression affects binding
EXP ISO
Dinitrochlorobenzene results in increased expression of MCM3 mRNA Dinitrochlorobenzene binds to MCM3 protein
CTD
PMID:21404309 PMID:32991956
NCBI chr 1:20,873,188...20,890,536
Ensembl chr 1:20,873,192...20,890,536
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Mcm4
minichromosome maintenance complex component 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of MCM4 mRNA
CTD
PMID:21404309
NCBI chr16:15,441,761...15,455,264
Ensembl chr16:15,441,761...15,455,264
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Mcm5
minichromosome maintenance complex component 5
increases expression affects binding
EXP ISO
Dinitrochlorobenzene results in increased expression of MCM5 mRNA Dinitrochlorobenzene binds to MCM5 protein
CTD
PMID:21404309 PMID:32991956
NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067
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Mcm6
minichromosome maintenance complex component 6
increases expression
EXP
Dinitrochlorobenzene results in increased expression of MCM6 mRNA
CTD
PMID:21404309
NCBI chr 1:128,259,312...128,287,442
Ensembl chr 1:128,259,327...128,287,401
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Mcm7
minichromosome maintenance complex component 7
increases expression
EXP
Dinitrochlorobenzene results in increased expression of MCM7 mRNA
CTD
PMID:21404309
NCBI chr 5:138,162,845...138,170,675
Ensembl chr 5:138,162,845...138,170,684
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Mcpt1
mast cell protease 1
affects expression
EXP
Dinitrochlorobenzene affects the expression of MCPT1 mRNA
CTD
PMID:22302311
NCBI chr14:56,255,421...56,257,848
Ensembl chr14:56,255,428...56,257,841
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Mcpt8
mast cell protease 8
affects expression
EXP
Dinitrochlorobenzene affects the expression of MCPT8 mRNA
CTD
PMID:22302311
NCBI chr14:56,319,620...56,322,951
Ensembl chr14:56,319,623...56,322,730
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Mcts1
malignant T cell amplified sequence 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MCTS1 mRNA
CTD
PMID:17374397
NCBI chr X:37,653,682...37,702,401
Ensembl chr X:37,689,455...37,702,303
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Mdh2
malate dehydrogenase 2, NAD (mitochondrial)
affects binding
ISO
Dinitrochlorobenzene binds to MDH2 protein
CTD
PMID:32991956
NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
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Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of ME1 mRNA Dinitrochlorobenzene binds to ME1 protein
CTD
PMID:20566472 PMID:32991956
NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
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Mgmt
O-6-methylguanine-DNA methyltransferase
affects binding
ISO
Dinitrochlorobenzene binds to MGMT protein
CTD
PMID:12974631
NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
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Mgst1
microsomal glutathione S-transferase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MGST1 mRNA
CTD
PMID:20566472
NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753
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Mink1
misshapen-like kinase 1 (zebrafish)
affects binding
ISO
Dinitrochlorobenzene binds to MINK1 protein
CTD
PMID:32991956
NCBI chr11:70,452,272...70,505,309
Ensembl chr11:70,453,707...70,505,309
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Mki67
antigen identified by monoclonal antibody Ki 67
affects expression affects binding
EXP ISO
Dinitrochlorobenzene affects the expression of MKI67 mRNA Dinitrochlorobenzene binds to MKI67 protein
CTD
PMID:22302311 PMID:32991956
NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
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Mmp10
matrix metallopeptidase 10
affects expression
EXP
Dinitrochlorobenzene affects the expression of MMP10 mRNA
CTD
PMID:22302311
NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
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Mmp12
matrix metallopeptidase 12
increases expression
EXP
Dinitrochlorobenzene results in increased expression of MMP12 mRNA
CTD
PMID:10216232
NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
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Mmp1b
matrix metallopeptidase 1b (interstitial collagenase)
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MMP1 mRNA
CTD
PMID:20146380
NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MMP3 mRNA
CTD
PMID:20146380
NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
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Mob1a
MOB kinase activator 1A
affects binding
ISO
Dinitrochlorobenzene binds to MOB1A protein
CTD
PMID:32991956
NCBI chr 6:83,303,016...83,320,758
Ensembl chr 6:83,302,998...83,320,758
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Mob1b
MOB kinase activator 1B
affects binding
ISO
Dinitrochlorobenzene binds to MOB1B protein
CTD
PMID:32991956
NCBI chr 5:88,868,730...88,906,314
Ensembl chr 5:88,868,714...88,912,079
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Mpo
myeloperoxidase
multiple interactions decreases activity decreases expression
ISO
Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein]; Sulfasalazine inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein] Dinitrochlorobenzene results in decreased expression of MPO mRNA
CTD
PMID:17373747 PMID:17374397
NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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Mrpl28
mitochondrial ribosomal protein L28
affects binding
ISO
Dinitrochlorobenzene binds to MRPL28 protein
CTD
PMID:32991956
NCBI chr17:26,342,477...26,345,587
Ensembl chr17:26,342,474...26,345,587
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Mrpl35
mitochondrial ribosomal protein L35
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MRPL35 mRNA
CTD
PMID:17374397
NCBI chr 6:71,789,981...71,800,768
Ensembl chr 6:71,789,981...71,803,953
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Mrps5
mitochondrial ribosomal protein S5
affects binding
ISO
Dinitrochlorobenzene binds to MRPS5 protein
CTD
PMID:32991956
NCBI chr 2:127,429,346...127,445,906
Ensembl chr 2:127,429,142...127,448,749
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Mrps6
mitochondrial ribosomal protein S6
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MRPS6 mRNA
CTD
PMID:17374397
NCBI chr16:91,855,224...91,909,115
Ensembl chr16:91,855,158...91,909,115
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Ms4a7
membrane-spanning 4-domains, subfamily A, member 7
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MS4A7 mRNA
CTD
PMID:17374397
NCBI chr19:11,298,403...11,313,510
Ensembl chr19:11,298,403...11,313,510
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Msh2
mutS homolog 2
affects binding
ISO
Dinitrochlorobenzene binds to MSH2 protein
CTD
PMID:32991956
NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
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Msh6
mutS homolog 6
affects binding
ISO
Dinitrochlorobenzene binds to MSH6 protein
CTD
PMID:32991956
NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
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Msn
moesin
affects binding
ISO
Dinitrochlorobenzene binds to MSN protein
CTD
PMID:32991956
NCBI chr X:95,139,651...95,212,159
Ensembl chr X:95,139,648...95,212,158
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Mt1
metallothionein 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MT1X mRNA
CTD
PMID:20566472
NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
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Mt2
metallothionein 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MT2A mRNA
CTD
PMID:20491607
NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
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Mtap
methylthioadenosine phosphorylase
affects binding
ISO
Dinitrochlorobenzene binds to MTAP protein
CTD
PMID:32991956
NCBI chr 4:89,055,607...89,099,327
Ensembl chr 4:89,055,359...89,099,318
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Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
affects binding
ISO
Dinitrochlorobenzene binds to MTBP protein
CTD
PMID:32991956
NCBI chr15:55,420,800...55,489,819
Ensembl chr15:55,420,804...55,489,819
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Mthfd1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
affects binding
ISO
Dinitrochlorobenzene binds to MTHFD1 protein
CTD
PMID:32991956
NCBI chr12:76,301,180...76,366,594
Ensembl chr12:76,302,072...76,366,577
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Mx1
MX dynamin-like GTPase 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of MX2 mRNA
CTD
PMID:19647056
NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107
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Myb
myeloblastosis oncogene
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MYB mRNA
CTD
PMID:17374397
NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883
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Myc
myelocytomatosis oncogene
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MYC mRNA
CTD
PMID:17374397
NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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Myh11
myosin, heavy polypeptide 11, smooth muscle
affects binding
ISO
Dinitrochlorobenzene binds to MYH11 protein
CTD
PMID:32991956
NCBI chr16:14,012,392...14,109,227
Ensembl chr16:14,012,399...14,109,236
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Myh9
myosin, heavy polypeptide 9, non-muscle
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of MYH9 protein Dinitrochlorobenzene binds to MYH9 protein
CTD
PMID:29267982 PMID:32991956
NCBI chr15:77,644,788...77,726,315
Ensembl chr15:77,644,787...77,726,375
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Myl6b
myosin, light polypeptide 6B
affects binding
ISO
Dinitrochlorobenzene binds to MYL6B protein
CTD
PMID:32991956
NCBI chr10:128,330,026...128,334,554
Ensembl chr10:128,330,026...128,334,554
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Myo1b
myosin IB
affects binding
ISO
Dinitrochlorobenzene binds to MYO1B protein
CTD
PMID:32991956
NCBI chr 1:51,788,915...51,955,143
Ensembl chr 1:51,788,924...51,955,230
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Myo1d
myosin ID
affects binding
ISO
Dinitrochlorobenzene binds to MYO1D protein
CTD
PMID:32991956
NCBI chr11:80,372,945...80,670,881
Ensembl chr11:80,372,952...80,670,851
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Myo1e
myosin IE
affects binding
ISO
Dinitrochlorobenzene binds to MYO1E protein
CTD
PMID:32991956
NCBI chr 9:70,114,632...70,307,349
Ensembl chr 9:70,114,632...70,307,048
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Nae1
NEDD8 activating enzyme E1 subunit 1
affects binding
ISO
Dinitrochlorobenzene binds to NAE1 protein
CTD
PMID:32991956
NCBI chr 8:105,237,660...105,261,269
Ensembl chr 8:105,237,660...105,261,269
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Nagk
N-acetylglucosamine kinase
affects binding
ISO
Dinitrochlorobenzene binds to NAGK protein
CTD
PMID:32991956
NCBI chr 6:83,770,810...83,779,538
Ensembl chr 6:83,771,964...83,781,000
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Nampt
nicotinamide phosphoribosyltransferase
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of NAMPT mRNA Dinitrochlorobenzene binds to NAMPT protein
CTD
PMID:17374397 PMID:19371601 PMID:32991956
NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
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Naprt
nicotinate phosphoribosyltransferase
affects binding
ISO
Dinitrochlorobenzene binds to NAPRT protein
CTD
PMID:32991956
NCBI chr15:75,762,812...75,766,330
Ensembl chr15:75,762,805...75,766,330
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Ndrg3
N-myc downstream regulated gene 3
affects binding
ISO
Dinitrochlorobenzene binds to NDRG3 protein
CTD
PMID:32991956
NCBI chr 2:156,769,262...156,834,052
Ensembl chr 2:156,769,265...156,833,976
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Ndufa2
NADH:ubiquinone oxidoreductase subunit A2
affects binding
ISO
Dinitrochlorobenzene binds to NDUFA2 protein
CTD
PMID:32991956
NCBI chr18:36,875,385...36,877,640
Ensembl chr18:36,875,385...36,877,610
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Nefh
neurofilament, heavy polypeptide
affects binding
ISO
Dinitrochlorobenzene binds to NEFH protein
CTD
PMID:32991956
NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
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Nfe2l2
nuclear factor, erythroid derived 2, like 2
multiple interactions affects response to substance increases expression affects expression decreases expression
ISO EXP
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFE2L2 protein]; Dinitrochlorobenzene affects the localization of and results in increased activity of NFE2L2 protein; NFE2L2 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA]; NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA] Dinitrochlorobenzene affects the localization of and results in increased activity of NFE2L2 protein; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in decreased abundance of Glutathione]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased abundance of Reactive Oxygen Species]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL3 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL1 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL10 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of BCL2 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of CAT mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX1 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX2 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX5 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX6 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GSR mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NFE2L2 mRNA] [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Dinitrochlorobenzene; NFE2L2 affects the susceptibility to Dinitrochlorobenzene Dinitrochlorobenzene affects the expression of NFE2L2 protein
CTD
PMID:18785192 PMID:19033392 PMID:19303893 PMID:19427879 PMID:23564646 PMID:26022718 PMID:26244607 PMID:27492222 PMID:27965148 PMID:28219650 PMID:31967339 PMID:34651546 More...
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
decreases expression affects expression multiple interactions increases expression
ISO EXP
Dinitrochlorobenzene results in decreased expression of NFKB1 mRNA Dinitrochlorobenzene affects the expression of NFKB1 mRNA sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFKB1 mRNA]
CTD
PMID:20385217 PMID:28219650 PMID:34651546
NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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Ninj1
ninjurin 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NINJ1 mRNA
CTD
PMID:16314067 PMID:17374397
NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720
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Nlrp12
NLR family, pyrin domain containing 12
decreases expression multiple interactions
ISO
Dinitrochlorobenzene results in decreased expression of NLRP12 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]; Dinitrochlorobenzene results in decreased expression of and affects the localization of NLRP12 protein
CTD
PMID:27585668 PMID:31276767
NCBI chr 7:3,267,317...3,298,400
Ensembl chr 7:3,267,458...3,298,370
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Nlrp3
NLR family, pyrin domain containing 3
multiple interactions increases expression
ISO
Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] Dinitrochlorobenzene results in increased expression of NLRP3 protein
CTD
PMID:31276767
NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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Nolc1
nucleolar and coiled-body phosphoprotein 1
affects binding
ISO
Dinitrochlorobenzene binds to NOLC1 protein
CTD
PMID:32991956
NCBI chr19:46,064,286...46,073,982
Ensembl chr19:46,064,302...46,073,969
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Nop2
NOP2 nucleolar protein
affects binding
ISO
Dinitrochlorobenzene binds to NOP2 protein
CTD
PMID:32991956
NCBI chr 6:125,108,829...125,121,716
Ensembl chr 6:125,108,872...125,121,716
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Nos2
nitric oxide synthase 2, inducible
multiple interactions increases expression affects expression
ISO EXP
Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NOS2 protein] Dinitrochlorobenzene results in increased expression of NOS2 protein NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of NOS2 mRNA] Dinitrochlorobenzene affects the expression of NOS2 mRNA
CTD
PMID:17373747 PMID:28219650
NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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Npr3
natriuretic peptide receptor 3
affects expression
ISO
Dinitrochlorobenzene affects the expression of NPR3 mRNA
CTD
PMID:19527780
NCBI chr15:11,839,982...11,907,287
Ensembl chr15:11,839,982...11,907,373
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Nqo1
NAD(P)H dehydrogenase, quinone 1
multiple interactions increases expression
ISO EXP
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NQO1 mRNA]
CTD
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20491607 PMID:20566472 PMID:28219650 More...
NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Nr0b1
nuclear receptor subfamily 0, group B, member 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NR0B1 mRNA
CTD
PMID:20146380
NCBI chr X:85,235,381...85,239,553
Ensembl chr X:85,235,370...85,239,553
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NR3C1 mRNA
CTD
PMID:17374397
NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
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Nrdc
nardilysin convertase
affects binding
ISO
Dinitrochlorobenzene binds to NRDC protein
CTD
PMID:32991956
NCBI chr 4:108,857,852...108,918,974
Ensembl chr 4:108,857,852...108,918,974
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Nrep
neuronal regeneration related protein
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of NREP mRNA
CTD
PMID:17374397
NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082
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Nrf1
nuclear respiratory factor 1
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of NRF1 mRNA
CTD
PMID:28219650
NCBI chr 6:30,047,984...30,153,462
Ensembl chr 6:30,047,987...30,153,457
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Nsdhl
NAD(P) dependent steroid dehydrogenase-like
affects binding
ISO
Dinitrochlorobenzene binds to NSDHL protein
CTD
PMID:32991956
NCBI chr X:71,962,127...72,002,134
Ensembl chr X:71,962,163...72,002,120
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Nt5dc1
5'-nucleotidase domain containing 1
affects binding
ISO
Dinitrochlorobenzene binds to NT5DC1 protein
CTD
PMID:32991956
NCBI chr10:34,179,605...34,294,585
Ensembl chr10:34,164,284...34,294,548
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Numa1
nuclear mitotic apparatus protein 1
affects binding
ISO
Dinitrochlorobenzene binds to NUMA1 protein
CTD
PMID:32991956
NCBI chr 7:101,583,169...101,664,166
Ensembl chr 7:101,583,318...101,664,171
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Nup155
nucleoporin 155
affects binding
ISO
Dinitrochlorobenzene binds to NUP155 protein
CTD
PMID:32991956
NCBI chr15:8,135,861...8,189,343
Ensembl chr15:8,138,757...8,190,731
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Nup205
nucleoporin 205
affects binding
ISO
Dinitrochlorobenzene binds to NUP205 protein
CTD
PMID:32991956
NCBI chr 6:35,154,551...35,224,534
Ensembl chr 6:35,154,356...35,224,531
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Nup43
nucleoporin 43
increases methylation
EXP
Dinitrochlorobenzene results in increased methylation of NUP43 promoter
CTD
PMID:24675093
NCBI chr10:7,543,268...7,554,650
Ensembl chr10:7,543,267...7,554,645
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Nup88
nucleoporin 88
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NUP88 mRNA
CTD
PMID:17374397
NCBI chr11:70,833,884...70,860,799
Ensembl chr11:70,833,884...70,860,799
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Oasl2
2'-5' oligoadenylate synthetase-like 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of OASL2 mRNA
CTD
PMID:19647056
NCBI chr 5:115,034,995...115,050,306
Ensembl chr 5:115,034,997...115,050,295
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Odc1
ornithine decarboxylase, structural 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ODC1 mRNA
CTD
PMID:21404309
NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
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Ola1
Obg-like ATPase 1
affects binding
ISO
Dinitrochlorobenzene binds to OLA1 protein
CTD
PMID:32991956
NCBI chr 2:72,923,145...73,044,791
Ensembl chr 2:72,923,145...73,049,268
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Orc1
origin recognition complex, subunit 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ORC1 mRNA
CTD
PMID:21404309
NCBI chr 4:108,436,651...108,472,030
Ensembl chr 4:108,436,620...108,472,030
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Orc5
origin recognition complex, subunit 5
affects binding
ISO
Dinitrochlorobenzene binds to ORC5 protein
CTD
PMID:32991956
NCBI chr 5:22,691,478...22,755,358
Ensembl chr 5:22,691,483...22,755,427
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Orc6
origin recognition complex, subunit 6
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ORC6 mRNA
CTD
PMID:21404309
NCBI chr 8:86,026,261...86,034,908
Ensembl chr 8:86,026,261...86,034,907
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Osm
oncostatin M
increases expression
EXP
Dinitrochlorobenzene results in increased expression of OSM mRNA
CTD
PMID:19647056
NCBI chr11:4,186,831...4,191,027
Ensembl chr11:4,186,420...4,191,026
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Otud1
OTU domain containing 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of OTUD1 mRNA
CTD
PMID:17374397
NCBI chr 2:19,662,542...19,666,090
Ensembl chr 2:19,662,563...19,665,394
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Oxsr1
oxidative-stress responsive 1
affects binding
ISO
Dinitrochlorobenzene binds to OXSR1 protein
CTD
PMID:32991956
NCBI chr 9:119,067,498...119,154,475
Ensembl chr 9:119,067,498...119,151,493
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P4hb
prolyl 4-hydroxylase, beta polypeptide
affects binding
ISO
Dinitrochlorobenzene binds to P4HB protein
CTD
PMID:32991956
NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
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Padi4
peptidyl arginine deiminase, type IV
affects binding
ISO
Dinitrochlorobenzene binds to PADI4 protein
CTD
PMID:32991956
NCBI chr 4:140,472,819...140,501,514
Ensembl chr 4:140,473,176...140,501,547
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Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of PAICS mRNA
CTD
PMID:17374397
NCBI chr 5:77,099,149...77,115,356
Ensembl chr 5:77,099,154...77,115,356
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Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
affects binding
ISO
Dinitrochlorobenzene binds to PAPSS1 protein
CTD
PMID:32991956
NCBI chr 3:131,270,626...131,349,432
Ensembl chr 3:131,270,529...131,349,432
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Parp1
poly (ADP-ribose) polymerase family, member 1
affects binding
ISO
Dinitrochlorobenzene binds to PARP1 protein
CTD
PMID:32991956
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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Pcna
proliferating cell nuclear antigen
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PCNA mRNA
CTD
PMID:21404309
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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Pcsk9
proprotein convertase subtilisin/kexin type 9
affects binding
ISO
Dinitrochlorobenzene binds to PCSK9 protein
CTD
PMID:32991956
NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526
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Pde4b
phosphodiesterase 4B, cAMP specific
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PDE4B mRNA
CTD
PMID:17374397
NCBI chr 4:101,944,529...102,464,459
Ensembl chr 4:101,944,740...102,464,456
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Pde4d
phosphodiesterase 4D, cAMP specific
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PDE4D mRNA
CTD
PMID:17374397
NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
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Pdhb
pyruvate dehydrogenase (lipoamide) beta
affects binding
ISO
Dinitrochlorobenzene binds to PDHB protein
CTD
PMID:32991956
NCBI chr14:14,296,470...14,303,782
Ensembl chr14:14,296,748...14,303,777
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Pdia4
protein disulfide isomerase associated 4
affects binding
ISO
Dinitrochlorobenzene binds to PDIA4 protein
CTD
PMID:32991956
NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364
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Pds5b
PDS5 cohesin associated factor B
affects binding
ISO
Dinitrochlorobenzene binds to PDS5B protein
CTD
PMID:32991956
NCBI chr 5:150,597,178...150,734,174
Ensembl chr 5:150,597,204...150,734,155
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Pf4
platelet factor 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PF4 mRNA
CTD
PMID:19647056
NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242
G
Pfkl
phosphofructokinase, liver, B-type
affects binding
ISO
Dinitrochlorobenzene binds to PFKL protein
CTD
PMID:32991956
NCBI chr10:77,822,781...77,845,641
Ensembl chr10:77,822,781...77,845,917
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Pgd
phosphogluconate dehydrogenase
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of PGD mRNA Dinitrochlorobenzene binds to PGD protein
CTD
PMID:20566472 PMID:32991956
NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
G
Phf11d
PHD finger protein 11D
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PHF11 mRNA
CTD
PMID:19647056
NCBI chr14:59,584,646...59,608,004
Ensembl chr14:59,584,856...59,602,919
G
Phlda1
pleckstrin homology like domain, family A, member 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PHLDA1 mRNA
CTD
PMID:17374397
NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
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Picalm
phosphatidylinositol binding clathrin assembly protein
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PICALM mRNA
CTD
PMID:17374397
NCBI chr 7:89,778,711...89,858,655
Ensembl chr 7:89,779,421...89,862,673
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Pir
pirin
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PIR mRNA
CTD
PMID:16314067
NCBI chr X:163,052,427...163,156,009
Ensembl chr X:163,052,367...163,156,007
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Pkm
pyruvate kinase, muscle
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of PKM protein
CTD
PMID:29267982
NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
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Plat
plasminogen activator, tissue
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PLAT mRNA
CTD
PMID:17374397
NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
G
Plekhm3
pleckstrin homology domain containing, family M, member 3
increases methylation
EXP
Dinitrochlorobenzene results in increased methylation of PLEKHM3 promoter
CTD
PMID:24675093
NCBI chr 1:64,828,279...64,995,983
Ensembl chr 1:64,825,142...64,995,983
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Plin2
perilipin 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PLIN2 mRNA
CTD
PMID:16314067
NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
G
Plk1
polo like kinase 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PLK1 mRNA
CTD
PMID:21404309
NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PMAIP1 mRNA
CTD
PMID:20713136
NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
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Pola1
polymerase (DNA directed), alpha 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of POLA1 mRNA
CTD
PMID:21404309
NCBI chr X:92,348,372...92,675,993
Ensembl chr X:92,348,373...92,675,761
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Pold3
polymerase (DNA-directed), delta 3, accessory subunit
increases expression
EXP
Dinitrochlorobenzene results in increased expression of POLD3 mRNA
CTD
PMID:21404309
NCBI chr 7:99,731,317...99,770,709
Ensembl chr 7:99,731,318...99,770,772
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Pole
polymerase (DNA directed), epsilon
increases expression
EXP
Dinitrochlorobenzene results in increased expression of POLE mRNA
CTD
PMID:21404309
NCBI chr 5:110,434,185...110,485,319
Ensembl chr 5:110,434,172...110,485,340
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Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
affects binding
ISO
Dinitrochlorobenzene binds to POLR2A protein
CTD
PMID:32991956
NCBI chr11:69,624,823...69,649,459
Ensembl chr11:69,624,823...69,649,463
G
Ppa1
pyrophosphatase (inorganic) 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PPA1 mRNA
CTD
PMID:18242016
NCBI chr10:61,484,400...61,509,944
Ensembl chr10:61,484,331...61,509,947
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Ppbp
pro-platelet basic protein
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PPBP mRNA
CTD
PMID:19647056
NCBI chr 5:90,916,377...90,917,922
Ensembl chr 5:90,916,377...90,917,922
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Ppif
peptidylprolyl isomerase F (cyclophilin F)
increases oxidation
ISO
Dinitrochlorobenzene results in increased oxidation of PPIF protein
CTD
PMID:26975474
NCBI chr14:25,693,998...25,700,892
Ensembl chr14:25,694,578...25,700,892
G
Ppl
periplakin
affects binding
ISO
Dinitrochlorobenzene binds to PPL protein
CTD
PMID:32991956
NCBI chr16:4,904,155...4,950,345
Ensembl chr16:4,904,155...4,950,285
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Ppp1ca
protein phosphatase 1 catalytic subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to PPP1CA protein
CTD
PMID:32991956
NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419
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Ppp2r1b
protein phosphatase 2, regulatory subunit A, beta
affects binding
ISO
Dinitrochlorobenzene binds to PPP2R1B protein
CTD
PMID:32991956
NCBI chr 9:50,767,946...50,810,625
Ensembl chr 9:50,756,601...50,805,529
G
Ppp2r5c
protein phosphatase 2, regulatory subunit B', gamma
affects binding
ISO
Dinitrochlorobenzene binds to PPP2R5C protein
CTD
PMID:32991956
NCBI chr12:110,413,532...110,549,509
Ensembl chr12:110,413,554...110,549,496
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Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
affects binding
ISO
Dinitrochlorobenzene binds to PPP3CA protein
CTD
PMID:32991956
NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488
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Ppt1
palmitoyl-protein thioesterase 1
affects binding
ISO
Dinitrochlorobenzene binds to PPT1 protein
CTD
PMID:32991956
NCBI chr 4:122,729,879...122,752,968
Ensembl chr 4:122,730,035...122,752,968
G
Ppwd1
peptidylprolyl isomerase domain and WD repeat containing 1
affects binding
ISO
Dinitrochlorobenzene binds to PPWD1 protein
CTD
PMID:32991956
NCBI chr13:104,340,102...104,365,378
Ensembl chr13:104,341,632...104,365,351
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Prdm1
PR domain containing 1, with ZNF domain
multiple interactions increases expression
ISO
BAY 11-7085 inhibits the reaction [Dinitrochlorobenzene results in increased expression of PRDM1 mRNA]; BAY 11-7085 inhibits the reaction [Dinitrochlorobenzene results in increased expression of PRDM1 protein]; PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein] Dinitrochlorobenzene results in increased expression of PRDM1 mRNA; Dinitrochlorobenzene results in increased expression of PRDM1 protein
CTD
PMID:27585668 PMID:31276767
NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497
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Prdx1
peroxiredoxin 1
affects oxidation affects binding
ISO
Dinitrochlorobenzene affects the oxidation of PRDX1 protein Dinitrochlorobenzene binds to PRDX1 protein
CTD
PMID:18789312 PMID:32991956
NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
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Prdx2
peroxiredoxin 2
increases oxidation
ISO
Dinitrochlorobenzene results in increased oxidation of PRDX2 protein
CTD
PMID:18789312
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
G
Prdx3
peroxiredoxin 3
decreases expression increases oxidation
ISO
Dinitrochlorobenzene results in decreased expression of PRDX3 mRNA Dinitrochlorobenzene results in increased oxidation of PRDX3 protein
CTD
PMID:17374397 PMID:18789312 PMID:26975474
NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994
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Prim1
DNA primase, p49 subunit
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PRIM1 mRNA
CTD
PMID:21404309
NCBI chr10:127,851,084...127,865,899
Ensembl chr10:127,851,041...127,865,906
G
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
affects binding
ISO
Dinitrochlorobenzene binds to PRKAR1A protein
CTD
PMID:32991956
NCBI chr11:109,539,849...109,560,489
Ensembl chr11:109,540,231...109,560,482
G
Prkcb
protein kinase C, beta
affects localization
ISO
Dinitrochlorobenzene affects the localization of PRKCB protein
CTD
PMID:24136171
NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
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Prkdc
protein kinase, DNA activated, catalytic polypeptide
affects binding
ISO
Dinitrochlorobenzene binds to PRKDC protein
CTD
PMID:32991956
NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
G
Prl2c3
prolactin family 2, subfamily c, member 3
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PRL2C3 mRNA
CTD
PMID:19647056
NCBI chr13:12,805,705...12,814,982
Ensembl chr13:12,805,705...12,814,968
G
Prpf6
pre-mRNA splicing factor 6
affects binding
ISO
Dinitrochlorobenzene binds to PRPF6 protein
CTD
PMID:32991956
NCBI chr 2:181,243,112...181,297,454
Ensembl chr 2:181,233,661...181,297,453
G
Psap
prosaposin
affects binding
ISO
Dinitrochlorobenzene binds to PSAP protein
CTD
PMID:32991956
NCBI chr10:60,113,436...60,138,379
Ensembl chr10:60,113,449...60,138,376
G
Psma5
proteasome subunit alpha 5
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of PSMA5 mRNA Dinitrochlorobenzene binds to PSMA5 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr 3:108,164,242...108,187,268
Ensembl chr 3:108,164,242...108,187,290
G
Psmc5
protease (prosome, macropain) 26S subunit, ATPase 5
affects binding
ISO
Dinitrochlorobenzene binds to PSMC5 protein
CTD
PMID:32991956
NCBI chr11:106,147,011...106,153,938
Ensembl chr11:106,146,980...106,153,946
G
Psmd11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
affects binding
ISO
Dinitrochlorobenzene binds to PSMD11 protein
CTD
PMID:32991956
NCBI chr11:80,319,441...80,364,074
Ensembl chr11:80,319,441...80,364,074
G
Psmd5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
affects binding
ISO
Dinitrochlorobenzene binds to PSMD5 protein
CTD
PMID:32991956
NCBI chr 2:34,742,099...34,760,983
Ensembl chr 2:34,739,746...34,764,980
G
Psmd6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
affects binding
ISO
Dinitrochlorobenzene binds to PSMD6 protein
CTD
PMID:32991956
NCBI chr14:8,348,818...8,357,578
Ensembl chr14:8,348,779...8,357,589
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Psme4
proteasome (prosome, macropain) activator subunit 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PSME4 mRNA
CTD
PMID:21404309
NCBI chr11:30,721,753...30,831,150
Ensembl chr11:30,721,726...30,830,361
G
Ptcra
pre T cell antigen receptor alpha
affects expression
EXP
Dinitrochlorobenzene affects the expression of PTCRA mRNA
CTD
PMID:22302311
NCBI chr17:47,066,589...47,074,659
Ensembl chr17:47,066,589...47,074,638
G
Ptger3
prostaglandin E receptor 3 (subtype EP3)
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of PTGER3 mRNA
CTD
PMID:17374397
NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525
G
Ptgr1
prostaglandin reductase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PTGR1 mRNA
CTD
PMID:20566472
NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PTGS2 mRNA
CTD
PMID:19371601 PMID:20146380
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
G
Ptpn1
protein tyrosine phosphatase, non-receptor type 1
affects binding
ISO
Dinitrochlorobenzene binds to PTPN1 protein
CTD
PMID:32991956
NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
G
Pttg1
pituitary tumor-transforming gene 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of PTTG1 mRNA
CTD
PMID:21404309
NCBI chr11:43,311,097...43,317,417
Ensembl chr11:43,311,077...43,317,078
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Pycard
PYD and CARD domain containing
multiple interactions
ISO
Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]
CTD
PMID:31276767
NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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Pygl
liver glycogen phosphorylase
affects binding
ISO
Dinitrochlorobenzene binds to PYGL protein
CTD
PMID:32991956
NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
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Rab30
RAB30, member RAS oncogene family
affects binding
ISO
Dinitrochlorobenzene binds to RAB30 protein
CTD
PMID:32991956
NCBI chr 7:92,390,845...92,493,743
Ensembl chr 7:92,390,811...92,493,743
G
Rab32
RAB32, member RAS oncogene family
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of RAB32 mRNA
CTD
PMID:17374397
NCBI chr10:10,420,783...10,433,951
Ensembl chr10:10,420,746...10,434,009
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Rad50
RAD50 double strand break repair protein
affects binding
ISO
Dinitrochlorobenzene binds to RAD50 protein
CTD
PMID:32991956
NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
G
Rars1
arginyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to RARS1 protein
CTD
PMID:32991956
NCBI chr11:35,699,207...35,725,355
Ensembl chr11:35,699,208...35,725,333
G
Rasgrp1
RAS guanyl releasing protein 1
affects binding
ISO
Dinitrochlorobenzene binds to RASGRP1 protein
CTD
PMID:32991956
NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482
G
Rasl10a
RAS-like, family 10, member A
affects binding
ISO
Dinitrochlorobenzene binds to RASL10A protein
CTD
PMID:32991956
NCBI chr11:5,008,128...5,010,385
Ensembl chr11:5,008,128...5,010,385
G
Rbm17
RNA binding motif protein 17
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of RBM17 mRNA
CTD
PMID:17374397
NCBI chr 2:11,590,250...11,608,061
Ensembl chr 2:11,590,248...11,608,964
G
Rbm25
RNA binding motif protein 25
affects binding
ISO
Dinitrochlorobenzene binds to RBM25 protein
CTD
PMID:32991956
NCBI chr12:83,678,990...83,729,901
Ensembl chr12:83,678,010...83,729,897
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Rbm26
RNA binding motif protein 26
affects binding
ISO
Dinitrochlorobenzene binds to RBM26 protein
CTD
PMID:32991956
NCBI chr14:105,344,187...105,418,475
Ensembl chr14:105,344,187...105,414,763
G
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of RBPJ mRNA
CTD
PMID:17374397
NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704
G
Rcc1
regulator of chromosome condensation 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RCC1 mRNA
CTD
PMID:18242016
NCBI chr 4:132,059,230...132,073,061
Ensembl chr 4:132,059,230...132,080,916
G
Rdx
radixin
affects binding
ISO
Dinitrochlorobenzene binds to RDX protein
CTD
PMID:32991956
NCBI chr 9:51,958,450...52,000,038
Ensembl chr 9:51,958,473...52,011,763
G
Recql4
RecQ protein-like 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RECQL4 mRNA
CTD
PMID:18242016
NCBI chr15:76,587,753...76,594,820
Ensembl chr15:76,587,753...76,594,748
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions increases phosphorylation
ISO
aristolochic acid I inhibits the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein]; TLR4 protein promotes the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein]
CTD
PMID:31226360
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
G
Rfc3
replication factor C (activator 1) 3
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RFC3 mRNA
CTD
PMID:21404309
NCBI chr 5:151,566,282...151,574,673
Ensembl chr 5:151,566,221...151,574,707
G
Rfc4
replication factor C (activator 1) 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RFC4 mRNA
CTD
PMID:21404309
NCBI chr16:22,932,698...22,946,480
Ensembl chr16:22,932,693...22,946,487
G
Rfc5
replication factor C (activator 1) 5
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RFC5 mRNA
CTD
PMID:21404309
NCBI chr 5:117,517,210...117,527,088
Ensembl chr 5:117,516,168...117,527,112
G
Rgs1
regulator of G-protein signaling 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RGS1 mRNA
CTD
PMID:17374397
NCBI chr 1:144,120,407...144,124,862
Ensembl chr 1:144,118,034...144,124,980
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Rgs2
regulator of G-protein signaling 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RGS2 mRNA
CTD
PMID:20146380
NCBI chr 1:143,875,076...143,879,887
Ensembl chr 1:143,875,076...143,879,899
G
Rgs21
regulator of G-protein signalling 21
affects binding
ISO
Dinitrochlorobenzene binds to RGS21 protein
CTD
PMID:32991956
NCBI chr 1:144,392,388...144,443,185
Ensembl chr 1:144,392,386...144,443,405
G
Rhoc
ras homolog family member C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RHOC mRNA
CTD
PMID:16314067
NCBI chr 3:104,696,350...104,701,775
Ensembl chr 3:104,695,691...104,701,775
G
Rnase2a
ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of RNASE2A mRNA
CTD
PMID:18242016
NCBI chr14:51,492,718...51,493,569
Ensembl chr14:51,492,719...51,493,569
G
Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
affects binding
ISO
Dinitrochlorobenzene binds to RPL13AP3 protein
CTD
PMID:32991956
NCBI chr19:50,018,539...50,019,195
Ensembl chr19:50,018,563...50,019,174
G
Rpl27a
ribosomal protein L27A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RPL27A mRNA
CTD
PMID:17374397
NCBI chr 7:109,118,354...109,121,967
Ensembl chr 7:109,118,354...109,121,574
G
Rpl36
ribosomal protein L36
affects binding
ISO
Dinitrochlorobenzene binds to RPL36 protein
CTD
PMID:32991956
NCBI chr17:56,917,094...56,921,246
Ensembl chr17:56,920,416...56,921,243
G
Rpl9
ribosomal protein L9
affects binding
ISO
Dinitrochlorobenzene binds to RPL9 protein
CTD
PMID:32991956
NCBI chr 5:65,545,707...65,548,774
Ensembl chr 5:65,545,707...65,548,787
G
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
affects binding
ISO
Dinitrochlorobenzene binds to RPS6KA1 protein
CTD
PMID:32991956
NCBI chr 4:133,574,601...133,615,466
Ensembl chr 4:133,574,601...133,615,108
G
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
affects binding
ISO
Dinitrochlorobenzene binds to RPS6KA3 protein
CTD
PMID:32991956
NCBI chr X:158,038,652...158,151,240
Ensembl chr X:157,993,303...158,151,240
G
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
affects binding
ISO
Dinitrochlorobenzene binds to RPS6KA5 protein
CTD
PMID:32991956
NCBI chr12:100,514,692...100,691,693
Ensembl chr12:100,514,698...100,693,242
G
Rrm1
ribonucleotide reductase M1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RRM1 mRNA
CTD
PMID:21404309
NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978
G
Rrm2
ribonucleotide reductase M2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RRM2 mRNA
CTD
PMID:21404309
NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145
G
Rtn4ip1
reticulon 4 interacting protein 1
affects binding
ISO
Dinitrochlorobenzene binds to RTN4IP1 protein
CTD
PMID:32991956
NCBI chr10:43,777,772...43,823,860
Ensembl chr10:43,777,803...43,833,197
G
Rtp4
receptor transporter protein 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RTP4 mRNA
CTD
PMID:18242016 PMID:19647056
NCBI chr16:23,338,976...23,432,972
Ensembl chr16:23,339,041...23,432,972
G
Runx3
runt related transcription factor 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RUNX3 mRNA
CTD
PMID:21893156
NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
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S100a10
S100 calcium binding protein A10 (calpactin)
increases expression
ISO
Dinitrochlorobenzene results in increased expression of S100A10 mRNA
CTD
PMID:16314067
NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950
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S100b
S100 protein, beta polypeptide, neural
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of S100B mRNA
CTD
PMID:17374397
NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993
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Safb
scaffold attachment factor B
affects binding
ISO
Dinitrochlorobenzene binds to SAFB protein
CTD
PMID:32991956
NCBI chr17:56,891,982...56,913,294
Ensembl chr17:56,891,825...56,913,294
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Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SAT1 mRNA
CTD
PMID:17374397
NCBI chr X:153,996,128...153,999,345
Ensembl chr X:153,996,128...153,999,445
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Scyl1
SCY1-like 1 (S. cerevisiae)
affects binding
ISO
Dinitrochlorobenzene binds to SCYL1 protein
CTD
PMID:32991956
NCBI chr19:5,808,450...5,821,461
Ensembl chr19:5,808,379...5,821,447
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Sdc2
syndecan 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SDC2 mRNA
CTD
PMID:17374397
NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081
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Sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
affects binding
ISO
Dinitrochlorobenzene binds to SDHA protein
CTD
PMID:32991956
NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399
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Sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SEMA4C mRNA
CTD
PMID:16314067
NCBI chr 1:36,587,720...36,599,780
Ensembl chr 1:36,587,720...36,597,430
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Serbp1
serpine1 mRNA binding protein 1
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of SERBP1 mRNA Dinitrochlorobenzene binds to SERBP1 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr 6:67,243,963...67,266,286
Ensembl chr 6:67,215,160...67,274,720
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Serpinb13
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
affects binding
ISO
Dinitrochlorobenzene binds to SERPINB13 protein
CTD
PMID:32991956
NCBI chr 1:106,908,714...106,928,925
Ensembl chr 1:106,908,714...106,928,925
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Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of SERPINE1 mRNA
CTD
PMID:33774146
NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
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Sf3b1
splicing factor 3b, subunit 1
affects binding
ISO
Dinitrochlorobenzene binds to SF3B1 protein
CTD
PMID:32991956
NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640
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Sf3b3
splicing factor 3b, subunit 3
affects binding
ISO
Dinitrochlorobenzene binds to SF3B3 protein
CTD
PMID:32991956
NCBI chr 8:111,537,123...111,573,578
Ensembl chr 8:111,536,871...111,573,419
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Sh2b2
SH2B adaptor protein 2
decreases methylation
EXP
Dinitrochlorobenzene results in decreased methylation of SH2B2 promoter
CTD
PMID:24675093
NCBI chr 5:136,247,003...136,275,446
Ensembl chr 5:136,247,001...136,275,410
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Sis
sucrase isomaltase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SI mRNA
CTD
PMID:16314067
NCBI chr 3:72,795,890...72,875,196
Ensembl chr 3:72,795,890...72,875,196
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Skil
SKI-like
affects binding
ISO
Dinitrochlorobenzene binds to SKIL protein
CTD
PMID:32991956
NCBI chr 3:31,149,259...31,176,741
Ensembl chr 3:31,149,207...31,176,726
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Skp2
S-phase kinase-associated protein 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of SKP2 mRNA
CTD
PMID:21404309
NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512
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Slamf1
signaling lymphocytic activation molecule family member 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of SLAMF1 mRNA
CTD
PMID:20713136
NCBI chr 1:171,594,700...171,628,752
Ensembl chr 1:171,594,695...171,628,752
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Slamf8
SLAM family member 8
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of SLAMF8 mRNA
CTD
PMID:17374397
NCBI chr 1:172,408,944...172,418,482
Ensembl chr 1:172,409,325...172,418,135
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Slc12a9
solute carrier family 12 (potassium/chloride transporters), member 9
decreases methylation
EXP
Dinitrochlorobenzene results in decreased methylation of SLC12A9 promoter
CTD
PMID:24675093
NCBI chr 5:137,312,820...137,338,331
Ensembl chr 5:137,312,820...137,331,859
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Slc16a10
solute carrier family 16 (monocarboxylic acid transporters), member 10
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SLC16A10 mRNA
CTD
PMID:17374397
NCBI chr10:39,909,528...40,018,262
Ensembl chr10:39,909,528...40,018,254
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Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
affects binding
ISO
Dinitrochlorobenzene binds to SLC25A5 protein
CTD
PMID:32991956
NCBI chr X:36,059,250...36,062,461
Ensembl chr X:36,059,304...36,062,460
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Slc2a3
solute carrier family 2 (facilitated glucose transporter), member 3
increases expression decreases expression
ISO
Dinitrochlorobenzene results in increased expression of SLC2A3 mRNA Dinitrochlorobenzene results in decreased expression of SLC2A3 mRNA
CTD
PMID:17374397 PMID:19371601
NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
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Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SLC7A5 mRNA
CTD
PMID:17374397
NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
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Slpi
secretory leukocyte peptidase inhibitor
affects expression
EXP
Dinitrochlorobenzene affects the expression of SLPI mRNA
CTD
PMID:22302311
NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
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Smc1a
structural maintenance of chromosomes 1A
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of SMC1A mRNA
CTD
PMID:17374397
NCBI chr X:150,799,386...150,844,969
Ensembl chr X:150,799,424...150,845,690
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Snai1
snail family zinc finger 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SNAI1 mRNA
CTD
PMID:20146380
NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734
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Snu13
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
affects binding
ISO
Dinitrochlorobenzene binds to SNU13 protein
CTD
PMID:32991956
NCBI chr15:81,925,546...81,931,799
Ensembl chr15:81,924,726...81,931,799
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Snx15
sorting nexin 15
increases methylation
EXP
Dinitrochlorobenzene results in increased methylation of SNX15 promoter
CTD
PMID:24675093
NCBI chr19:6,169,429...6,182,446
Ensembl chr19:6,169,429...6,178,334
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Snx2
sorting nexin 2
affects binding
ISO
Dinitrochlorobenzene binds to SNX2 protein
CTD
PMID:32991956
NCBI chr18:53,309,362...53,353,938
Ensembl chr18:53,309,388...53,353,937
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Snx9
sorting nexin 9
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SNX9 mRNA
CTD
PMID:17374397
NCBI chr17:5,891,599...5,982,231
Ensembl chr17:5,891,604...5,982,229
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Sod1
superoxide dismutase 1, soluble
increases expression decreases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of SOD1 mRNA Dinitrochlorobenzene results in decreased expression of SOD1 mRNA
CTD
PMID:20566472 PMID:28219650
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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Sod2
superoxide dismutase 2, mitochondrial
increases expression multiple interactions decreases expression
ISO EXP
Dinitrochlorobenzene results in increased expression of SOD2 mRNA Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 protein] Dinitrochlorobenzene results in decreased expression of SOD2 mRNA
CTD
PMID:7476933 PMID:16314067 PMID:20566472 PMID:28219650
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Sod3
superoxide dismutase 3, extracellular
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SOD3 mRNA
CTD
PMID:20566472
NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
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Spp1
secreted phosphoprotein 1
multiple interactions
ISO
Dinitrochlorobenzene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; Dinitrochlorobenzene inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; Dinitrochlorobenzene inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]
CTD
PMID:20453393
NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
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Spta1
spectrin alpha, erythrocytic 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SPTA1 mRNA
CTD
PMID:16314067
NCBI chr 1:174,000,305...174,076,015
Ensembl chr 1:174,000,342...174,076,016
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Sqle
squalene epoxidase
increases expression
EXP
Dinitrochlorobenzene results in increased expression of SQLE mRNA
CTD
PMID:18242016
NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
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Srm
spermidine synthase
increases expression
EXP
Dinitrochlorobenzene results in increased expression of SRM mRNA
CTD
PMID:21404309
NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450
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Srp72
signal recognition particle 72
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of SRP72 mRNA Dinitrochlorobenzene binds to SRP72 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr 5:77,122,548...77,147,782
Ensembl chr 5:77,122,530...77,147,784
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Srrm1
serine/arginine repetitive matrix 1
affects binding
ISO
Dinitrochlorobenzene binds to SRRM1 protein
CTD
PMID:32991956
NCBI chr 4:135,047,795...135,080,787
Ensembl chr 4:135,047,795...135,080,632
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Srsf9
serine and arginine-rich splicing factor 9
affects binding
ISO
Dinitrochlorobenzene binds to SRSF9 protein
CTD
PMID:32991956
NCBI chr 5:115,465,236...115,471,139
Ensembl chr 5:115,465,236...115,471,139
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Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SRXN1 mRNA
CTD
PMID:20566472 PMID:25236440
NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
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Stat1
signal transducer and activator of transcription 1
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of STAT1 mRNA Dinitrochlorobenzene binds to STAT1 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
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Stat4
signal transducer and activator of transcription 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of STAT4 mRNA
CTD
PMID:17374397
NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348
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Stat5b
signal transducer and activator of transcription 5B
increases expression
ISO
Dinitrochlorobenzene results in increased expression of STAT5B mRNA
CTD
PMID:17374397
NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550
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Stau1
staufen double-stranded RNA binding protein 1
affects binding
ISO
Dinitrochlorobenzene binds to STAU1 protein
CTD
PMID:32991956
NCBI chr 2:166,789,469...166,838,253
Ensembl chr 2:166,789,469...166,838,219
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Stip1
stress-induced phosphoprotein 1
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of STIP1 protein
CTD
PMID:29267982
NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335
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Stx11
syntaxin 11
increases expression
ISO
Dinitrochlorobenzene results in increased expression of STX11 mRNA
CTD
PMID:17374397
NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042
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Supt16
SPT16, facilitates chromatin remodeling subunit
affects binding
ISO
Dinitrochlorobenzene binds to SUPT16H protein
CTD
PMID:32991956
NCBI chr14:52,397,876...52,434,696
Ensembl chr14:52,397,871...52,434,873
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Tars1
threonyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to TARS1 protein
CTD
PMID:32991956
NCBI chr15:11,383,749...11,399,744
Ensembl chr15:11,382,387...11,399,751
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Tbc1d4
TBC1 domain family, member 4
affects binding
ISO
Dinitrochlorobenzene binds to TBC1D4 protein
CTD
PMID:32991956
NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627
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Tex15
testis expressed gene 15 meiosis and synapsis associated
affects binding
ISO
Dinitrochlorobenzene binds to TEX15 protein
CTD
PMID:32991956
NCBI chr 8:34,006,712...34,082,531
Ensembl chr 8:34,006,766...34,075,610
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Tfdp1
transcription factor Dp 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TFDP1 mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr 8:13,388,273...13,428,448
Ensembl chr 8:13,388,751...13,428,448
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Tfec
transcription factor EC
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TFEC mRNA
CTD
PMID:19647056
NCBI chr 6:16,830,926...16,898,463
Ensembl chr 6:16,833,372...16,898,440
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Tgif1
TGFB-induced factor homeobox 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TGIF1 mRNA
CTD
PMID:17374397
NCBI chr17:71,151,200...71,160,527
Ensembl chr17:71,151,200...71,160,541
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Thbs1
thrombospondin 1
affects expression
EXP
Dinitrochlorobenzene affects the expression of THBS1 mRNA
CTD
PMID:22302311
NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
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Thbs4
thrombospondin 4
affects expression
EXP
Dinitrochlorobenzene affects the expression of THBS4 mRNA
CTD
PMID:22302311
NCBI chr13:92,888,094...92,931,326
Ensembl chr13:92,888,098...92,931,326
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Timd2
T cell immunoglobulin and mucin domain containing 2
affects expression
EXP
Dinitrochlorobenzene affects the expression of TIMD2 mRNA
CTD
PMID:22302311
NCBI chr11:46,559,787...46,597,934
Ensembl chr11:46,559,787...46,597,888
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Timm10b
translocase of inner mitochondrial membrane 10B
affects binding
ISO
Dinitrochlorobenzene binds to TIMM10B protein
CTD
PMID:32991956
NCBI chr 7:105,289,652...105,304,955
Ensembl chr 7:105,289,263...105,292,844 Ensembl chr 7:105,289,263...105,292,844
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Timp1
tissue inhibitor of metalloproteinase 1
affects expression
EXP
Dinitrochlorobenzene affects the expression of TIMP1 mRNA
CTD
PMID:22302311
NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974
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Timp3
tissue inhibitor of metalloproteinase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TIMP3 mRNA
CTD
PMID:16314067
NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370
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Tk1
thymidine kinase 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TK1 mRNA
CTD
PMID:21404309
NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918
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Tkt
transketolase
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of TKT protein
CTD
PMID:29267982
NCBI chr14:30,271,088...30,296,681
Ensembl chr14:30,270,316...30,296,677
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Tlr4
toll-like receptor 4
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of TLR4 mRNA; Dinitrochlorobenzene results in increased expression of TLR4 protein TLR4 protein promotes the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein]
CTD
PMID:31226360
NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
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Tmpo
thymopoietin
affects binding
ISO
Dinitrochlorobenzene binds to TMPO protein
CTD
PMID:32991956
NCBI chr10:90,983,433...91,017,614
Ensembl chr10:90,983,433...91,017,177
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Tnf
tumor necrosis factor
multiple interactions increases expression affects expression increases secretion
EXP ISO
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA; [Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; Dinitrochlorobenzene inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF protein] Dinitrochlorobenzene results in increased expression of TNF mRNA; Dinitrochlorobenzene results in increased expression of TNF protein [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of TNF protein; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; TNF protein affects the reaction [Dinitrochlorobenzene results in increased expression of CCR7 mRNA] Dinitrochlorobenzene affects the expression of TNF mRNA Dinitrochlorobenzene results in increased secretion of TNF protein
CTD
PMID:7476933 PMID:12202904 PMID:15304089 PMID:16675337 PMID:16687389 PMID:17118622 PMID:18495191 PMID:19647056 PMID:20385217 PMID:20417223 PMID:21782934 PMID:22245253 PMID:23200891 PMID:23454147 PMID:23499868 PMID:24964617 PMID:28826779 PMID:34651546 More...
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfaip3
tumor necrosis factor, alpha-induced protein 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TNFAIP3 mRNA
CTD
PMID:20146380
NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
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Tnfaip6
tumor necrosis factor alpha induced protein 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TNFAIP6 mRNA
CTD
PMID:17374397
NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
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Tnfrsf12a
tumor necrosis factor receptor superfamily, member 12a
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TNFRSF12A mRNA
CTD
PMID:19647056
NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
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Tnfrsf4
tumor necrosis factor receptor superfamily, member 4
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TNFRSF4 mRNA
CTD
PMID:21404309
NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069
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Tnfsf13
tumor necrosis factor (ligand) superfamily, member 13
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of TNFSF13 mRNA
CTD
PMID:21404309
NCBI chr11:69,573,403...69,576,380
Ensembl chr11:69,573,672...69,576,610
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Tnfsf14
tumor necrosis factor (ligand) superfamily, member 14
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TNFSF14 mRNA
CTD
PMID:19647056
NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177
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Tomm40
translocase of outer mitochondrial membrane 40
affects binding
ISO
Dinitrochlorobenzene binds to TOMM40 protein
CTD
PMID:32991956
NCBI chr 7:19,435,238...19,449,370
Ensembl chr 7:19,435,238...19,449,363
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Top2b
topoisomerase (DNA) II beta
affects binding
ISO
Dinitrochlorobenzene binds to TOP2B protein
CTD
PMID:32991956
NCBI chr14:6,038,976...6,104,585
Ensembl chr14:6,034,301...6,104,584
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Tpp2
tripeptidyl peptidase II
affects binding
ISO
Dinitrochlorobenzene binds to TPP2 protein
CTD
PMID:32991956
NCBI chr 1:43,973,130...44,042,160
Ensembl chr 1:43,972,807...44,042,160
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Tpr
translocated promoter region, nuclear basket protein
affects binding
ISO
Dinitrochlorobenzene binds to TPR protein
CTD
PMID:32991956
NCBI chr 1:150,268,544...150,325,686
Ensembl chr 1:150,268,589...150,325,686
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Trem1
triggering receptor expressed on myeloid cells 1
affects expression increases expression
ISO
Dinitrochlorobenzene affects the expression of TREM1 mRNA Dinitrochlorobenzene results in increased expression of TREM1 protein
CTD
PMID:33774146
NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952
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Trex1
three prime repair exonuclease 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TREX1 mRNA
CTD
PMID:21893156
NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802
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Trim28
tripartite motif-containing 28
affects binding
ISO
Dinitrochlorobenzene binds to TRIM28 protein
CTD
PMID:32991956
NCBI chr 7:12,758,079...12,764,959
Ensembl chr 7:12,733,041...12,764,962
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Trmt6
tRNA methyltransferase 6
affects binding
ISO
Dinitrochlorobenzene binds to TRMT6 protein
CTD
PMID:32991956
NCBI chr 2:132,646,127...132,658,127
Ensembl chr 2:132,646,127...132,657,975
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Trpm4
transient receptor potential cation channel, subfamily M, member 4
affects binding
ISO
Dinitrochlorobenzene binds to TRPM4 protein
CTD
PMID:32991956
NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204
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Trpm6
transient receptor potential cation channel, subfamily M, member 6
affects expression
EXP
Dinitrochlorobenzene affects the expression of TRPM6 mRNA
CTD
PMID:22302311
NCBI chr19:18,707,566...18,869,885
Ensembl chr19:18,727,347...18,869,875
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Tslp
thymic stromal lymphopoietin
increases expression multiple interactions
EXP
Dinitrochlorobenzene results in increased expression of TSLP mRNA [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TSLP mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TSLP mRNA]
CTD
PMID:19647056 PMID:23499868
NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850
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Ttc1
tetratricopeptide repeat domain 1
affects binding
ISO
Dinitrochlorobenzene binds to TTC1 protein
CTD
PMID:32991956
NCBI chr11:43,620,833...43,638,835
Ensembl chr11:43,620,339...43,638,835
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Txn1
thioredoxin 1
multiple interactions increases expression increases oxidation
ISO EXP
Dinitrochlorobenzene inhibits the reaction [Selegiline results in increased expression of TXN]; Dinitrochlorobenzene inhibits the reaction [TXN protein affects the susceptibility to Selegiline] Dinitrochlorobenzene results in increased expression of TXN1 mRNA Dinitrochlorobenzene results in increased oxidation of TXN protein
CTD
PMID:16099847 PMID:19647056 PMID:26975474
NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
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Txn2
thioredoxin 2
increases expression increases oxidation
ISO
Dinitrochlorobenzene results in increased expression of TXN2 mRNA Dinitrochlorobenzene results in increased oxidation of TXN2 protein
CTD
PMID:20566472 PMID:26975474
NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
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Txnrd1
thioredoxin reductase 1
multiple interactions increases expression increases oxidation
EXP ISO
Dinitrochlorobenzene inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid] Dinitrochlorobenzene results in increased expression of TXNRD1 mRNA Dinitrochlorobenzene results in increased oxidation of TXNRD1 protein [Dinitrochlorobenzene binds to TXNRD1 protein] inhibits the reaction [TXNRD1 protein results in increased reduction of Dithionitrobenzoic Acid]; Dinitrochlorobenzene promotes the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides]
CTD
PMID:17229725 PMID:17374397 PMID:20146380 PMID:20457604 PMID:20566472 PMID:21782934 More...
NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
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Txnrd2
thioredoxin reductase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TXNRD2 mRNA
CTD
PMID:20566472
NCBI chr16:18,245,167...18,297,823
Ensembl chr16:18,245,134...18,297,823
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Tyms
thymidylate synthase
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TYMS mRNA
CTD
PMID:21404309
NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
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Tyrobp
TYRO protein tyrosine kinase binding protein
decreases methylation
EXP
Dinitrochlorobenzene results in decreased methylation of TYROBP gene
CTD
PMID:26732893
NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010
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Ubac2
ubiquitin associated domain containing 2
affects binding
ISO
Dinitrochlorobenzene binds to UBAC2 protein
CTD
PMID:32991956
NCBI chr14:122,115,970...122,258,447
Ensembl chr14:122,116,032...122,258,446
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Ubd
ubiquitin D
increases expression
ISO
Dinitrochlorobenzene results in increased expression of UBD mRNA
CTD
PMID:21893156
NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986
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Ube2i
ubiquitin-conjugating enzyme E2I
affects binding
ISO
Dinitrochlorobenzene binds to UBE2I protein
CTD
PMID:32991956
NCBI chr17:25,479,484...25,494,965
Ensembl chr17:25,479,482...25,493,856
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Ubqln1
ubiquilin 1
affects binding
ISO
Dinitrochlorobenzene binds to UBQLN1 protein
CTD
PMID:32991956
NCBI chr13:58,323,970...58,363,467
Ensembl chr13:58,323,970...58,363,467
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Uchl5
ubiquitin carboxyl-terminal esterase L5
affects binding
ISO
Dinitrochlorobenzene binds to UCHL5 protein
CTD
PMID:32991956
NCBI chr 1:143,652,993...143,683,204
Ensembl chr 1:143,653,010...143,683,204
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Uck2
uridine-cytidine kinase 2
increases expression
EXP
Dinitrochlorobenzene results in increased expression of UCK2 mRNA
CTD
PMID:21404309
NCBI chr 1:167,050,464...167,112,657
Ensembl chr 1:167,050,452...167,112,889
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Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
increases expression
ISO
Dinitrochlorobenzene results in increased expression of UGT1A6 mRNA
CTD
PMID:20566472
NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
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Umps
uridine monophosphate synthetase
affects binding
ISO
Dinitrochlorobenzene binds to UMPS protein
CTD
PMID:32991956
NCBI chr16:33,775,152...33,787,408
Ensembl chr16:33,775,152...33,787,408
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Upb1
ureidopropionase, beta
decreases expression
EXP
Dinitrochlorobenzene results in decreased expression of UPB1 mRNA
CTD
PMID:21404309
NCBI chr10:75,242,745...75,277,513
Ensembl chr10:75,236,949...75,277,513
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Urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
affects binding
ISO
Dinitrochlorobenzene binds to URB1 protein
CTD
PMID:32991956
NCBI chr16:90,548,415...90,607,312
Ensembl chr16:90,548,415...90,607,301
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Usp18
ubiquitin specific peptidase 18
increases expression
EXP
Dinitrochlorobenzene results in increased expression of USP18 mRNA
CTD
PMID:19647056
NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876
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Utp20
UTP20 small subunit processome component
affects binding
ISO
Dinitrochlorobenzene binds to UTP20 protein
CTD
PMID:32991956
NCBI chr10:88,582,469...88,662,676
Ensembl chr10:88,582,469...88,662,666
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Utp25
UTP25 small subunit processome component
affects binding
ISO
Dinitrochlorobenzene binds to DIEXF protein
CTD
PMID:32991956
NCBI chr 1:192,786,707...192,812,603
Ensembl chr 1:192,773,412...192,812,580
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Vcl
vinculin
affects binding
ISO
Dinitrochlorobenzene binds to VCL protein
CTD
PMID:32991956
NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744
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Vcp
valosin containing protein
affects binding
ISO
Dinitrochlorobenzene binds to VCP protein
CTD
PMID:32991956
NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
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Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VDR mRNA
CTD
PMID:17374397
NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VEGFA protein
CTD
PMID:25617811
NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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Vegfc
vascular endothelial growth factor C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VEGFC mRNA
CTD
PMID:25617811
NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
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Vegfd
vascular endothelial growth factor D
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VEGFD mRNA
CTD
PMID:20146380
NCBI chr X:163,156,282...163,185,643
Ensembl chr X:163,156,374...163,185,646
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Vps29
VPS29 retromer complex component
affects binding
ISO
Dinitrochlorobenzene binds to VPS29 protein
CTD
PMID:32991956
NCBI chr 5:122,492,391...122,503,047
Ensembl chr 5:122,492,432...122,503,047
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Vsnl1
visinin-like 1
affects binding
ISO
Dinitrochlorobenzene binds to VSNL1 protein
CTD
PMID:32991956
NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614
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Wdr36
WD repeat domain 36
affects binding
ISO
Dinitrochlorobenzene binds to WDR36 protein
CTD
PMID:32991956
NCBI chr18:32,970,241...33,000,008
Ensembl chr18:32,970,278...33,000,647
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Zbp1
Z-DNA binding protein 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of ZBP1 mRNA
CTD
PMID:18242016 PMID:19647056
NCBI chr 2:173,048,405...173,060,715
Ensembl chr 2:173,048,405...173,060,716
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Zbtb17
zinc finger and BTB domain containing 17
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZBTB17 mRNA
CTD
PMID:17374397
NCBI chr 4:141,171,984...141,195,248
Ensembl chr 4:141,171,965...141,195,241
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Zfp326
zinc finger protein 326
affects binding
ISO
Dinitrochlorobenzene binds to ZNF326 protein
CTD
PMID:32991956
NCBI chr 5:106,024,422...106,063,684
Ensembl chr 5:106,024,431...106,063,684
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Zfp36l1
zinc finger protein 36, C3H type-like 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZFP36L1 mRNA
CTD
PMID:17374397
NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787
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Zfp469
zinc finger protein 469
affects binding
ISO
Dinitrochlorobenzene binds to ZNF469 protein
CTD
PMID:32991956
NCBI chr 8:122,770,009...122,999,389
Ensembl chr 8:122,985,359...122,999,389
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Zfyve26
zinc finger, FYVE domain containing 26
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZFYVE26 mRNA
CTD
PMID:17374397
NCBI chr12:79,279,120...79,343,102
Ensembl chr12:79,279,120...79,343,078
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Zmym3
zinc finger, MYM-type 3
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZMYM3 mRNA
CTD
PMID:17374397
NCBI chr X:100,447,990...100,464,986
Ensembl chr X:100,447,990...100,464,455
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