Rbpj (recombination signal binding protein for immunoglobulin kappa J region) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rbpj (recombination signal binding protein for immunoglobulin kappa J region) Mus musculus
Analyze
Symbol: Rbpj
Name: recombination signal binding protein for immunoglobulin kappa J region
RGD ID: 1321530
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including circulatory system development; positive regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including circulatory system development; epithelial cell differentiation; and regulation of gene expression. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; neural ectoderm; paraxial mesenchyme; and retina. Used to study aortic valve disease. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and dilated cardiomyopathy. Orthologous to human RBPJ (recombination signal binding protein for immunoglobulin kappa J region).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI843960; CBF1; Igk; Igkj; Igkjrb; Igkrsbp; j kappa-recombination signal-binding protein; RBP; RBP-J; RBP-J kappa; RBP-Jkappa; RBPjk; Rbpsuh; recombining binding protein suppressor of hairless
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rbpj-ps1   Rbpj-ps2   Rbpj-ps3  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39553,713,121 - 53,814,787 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl553,623,494 - 53,814,704 (+)EnsemblGRCm39 Ensembl
GRCm38553,555,779 - 53,657,445 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl553,466,152 - 53,657,362 (+)EnsemblGRCm38mm10GRCm38
MGSCv37553,947,018 - 54,048,684 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36553,878,593 - 53,944,281 (+)NCBIMGSCv36mm8
Celera550,938,216 - 51,041,035 (+)NCBICelera
Cytogenetic Map5C1NCBI
cM Map529.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-D-galactose  (EXP)
alpha-phellandrene  (ISO)
amitrole  (ISO)
ammonium chloride  (EXP,ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chloroquine  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cycloheximide  (ISO)
DAPT  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
enzalutamide  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
galactose  (EXP)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
ionomycin  (ISO)
irinotecan  (ISO)
kaempferol 3-O-beta-D-glucoside  (EXP)
lactacystin  (ISO)
lead diacetate  (ISO)
menadione  (EXP)
methimazole  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
nickel sulfate  (ISO)
oxaliplatin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rimonabant  (EXP)
SB 203580  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
thimerosal  (EXP)
thioacetamide  (ISO)
topotecan  (ISO)
triclosan  (EXP)
triptonide  (ISO)
triticonazole  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IMP)
aortic valve development  (IMP)
arterial endothelial cell fate commitment  (IMP)
artery morphogenesis  (IMP)
atrioventricular canal development  (IMP)
auditory receptor cell fate commitment  (IMP)
B cell differentiation  (IMP)
blood vessel endothelial cell fate specification  (IGI)
blood vessel lumenization  (IMP)
blood vessel remodeling  (IMP)
cardiac left ventricle morphogenesis  (IMP)
cardiac muscle cell myoblast differentiation  (IMP)
cell differentiation  (IMP)
cell fate commitment  (IMP)
cell population proliferation  (IGI,IMP)
club cell differentiation  (IMP)
defense response to bacterium  (IMP)
determination of heart left/right asymmetry  (TAS)
dorsal aorta morphogenesis  (IMP)
endocardium development  (IMP)
endocardium morphogenesis  (IMP)
epidermal cell fate specification  (IMP)
epithelial cell proliferation  (IGI)
epithelial to mesenchymal transition  (IMP)
epithelial to mesenchymal transition involved in endocardial cushion formation  (IMP)
hair follicle maturation  (IMP)
heart development  (IMP,ISO)
heart induction  (TAS)
heart looping  (TAS)
hemopoiesis  (IMP)
humoral immune response  (IMP)
inflammatory response to antigenic stimulus  (IMP)
keratinocyte differentiation  (IMP)
labyrinthine layer blood vessel development  (IMP)
myeloid dendritic cell differentiation  (IMP)
negative regulation of cell differentiation  (IMP)
negative regulation of cold-induced thermogenesis  (IMP)
negative regulation of DNA-templated transcription  (IDA,ISO)
negative regulation of neuron projection development  (ISO)
negative regulation of ossification  (IMP)
negative regulation of smooth muscle cell apoptotic process  (ISO)
negative regulation of smooth muscle cell migration  (ISO)
negative regulation of stem cell proliferation  (IMP)
negative regulation of transcription by RNA polymerase II  (IMP,ISO)
neuron differentiation  (IMP)
Notch signaling pathway  (IBA,IGI,IMP,ISO,TAS)
outflow tract morphogenesis  (IMP)
pituitary gland development  (IMP)
positive regulation of BMP signaling pathway  (IMP)
positive regulation of canonical Wnt signaling pathway  (IMP)
positive regulation of cardiac muscle cell proliferation  (IMP)
positive regulation of cell proliferation involved in heart morphogenesis  (IMP)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of ephrin receptor signaling pathway  (IMP)
positive regulation of epithelial cell proliferation  (IGI)
positive regulation of ERBB signaling pathway  (IMP)
positive regulation of gene expression  (IMP)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
positive regulation of transcription of Notch receptor target  (IGI,ISO)
pulmonary valve development  (IMP)
regulation of cell adhesion involved in heart morphogenesis  (IMP)
regulation of DNA-templated transcription  (IEA)
regulation of epithelial cell proliferation  (IGI)
regulation of gene expression  (IMP)
regulation of generation of precursor metabolites and energy  (ISO)
regulation of timing of cell differentiation  (IMP)
regulation of transcription by RNA polymerase II  (IGI,IMP)
sebaceous gland development  (IMP)
secondary heart field specification  (IGI,IMP)
somatic stem cell population maintenance  (IMP)
somitogenesis  (IMP,TAS)
stem cell proliferation  (IMP)
ventricular septum morphogenesis  (IMP)
ventricular trabecula myocardium morphogenesis  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior cardinal vein morphology  (IAGP)
abnormal aortic valve morphology  (IAGP)
abnormal atrioventricular cushion morphology  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal cardiac epithelial to mesenchymal transition  (IAGP)
abnormal CD4-positive helper T cell morphology  (IAGP)
abnormal cell differentiation  (IAGP)
abnormal centroacinar cell of Langerhans morphology  (IAGP)
abnormal common cardinal vein morphology  (IAGP)
abnormal crypts of Lieberkuhn morphology  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal decidualization  (IAGP)
abnormal diaphragm morphology  (IAGP)
abnormal digestion  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal dorsal interneuron 4 morphology  (IAGP)
abnormal epaxial muscle morphology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal glutaminergic neuron morphology  (IAGP)
abnormal hair follicle melanocyte morphology  (IAGP)
abnormal hair follicle melanogenesis  (IAGP)
abnormal heart development  (IAGP)
abnormal heart echocardiography feature  (IAGP)
abnormal heart morphology  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal intercostal muscle morphology  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal intestinal goblet cell morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lymphopoiesis  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal melanoblast morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal myogenesis  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal pancreas development  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal pancreas physiology  (IAGP)
abnormal pancreatic alpha cell differentiation  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal regulatory T cell physiology  (IAGP)
abnormal respiratory epithelium morphology  (IAGP)
abnormal response to infection  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal T-helper 2 cell differentiation  (IAGP)
abnormal vascular development  (IAGP)
abnormal vascular regression  (IAGP)
abnormal vitelline vascular remodeling  (IAGP)
absent club cells  (IAGP)
absent coat pigmentation  (IAGP)
absent podocytes  (IAGP)
absent vitelline blood vessels  (IAGP)
aortic valve inflammation  (IAGP)
arrested T cell differentiation  (IAGP)
arteriovenous malformation  (IAGP)
calcified aortic valve cusp  (IAGP)
cardiac fibrosis  (IAGP)
decreased bone mineral density  (IEA)
decreased cardiac muscle contractility  (IAGP)
decreased circulating HDL cholesterol level  (IEA)
decreased dendritic cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased follicular dendritic cell number  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased lymphatic vessel endothelial cell number  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased melanocyte number  (IAGP)
decreased neuronal precursor cell number  (IAGP)
decreased pancreatic acinar cell number  (IAGP)
decreased pancreatic islet number  (IAGP)
decreased satellite cell number  (IAGP)
decreased single-positive T cell number  (IAGP)
decreased skeletal muscle fiber density  (IAGP)
decreased spongiotrophoblast size  (IAGP)
decreased thymocyte number  (IAGP)
decreased tumor growth/size  (IAGP)
diluted coat color  (IAGP)
disorganized myocardium  (IAGP)
disorganized pancreatic islets  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality prior to tooth bud stage  (IEA)
embryonic lethality, incomplete penetrance  (IAGP)
epidermal cyst  (IAGP)
hypaxial muscle hypoplasia  (IAGP)
hyperkeratosis  (IAGP)
improved glucose tolerance  (IEA)
increased B cell number  (IAGP)
increased circulating bilirubin level  (IEA)
increased double-negative T cell number  (IAGP)
increased double-positive T cell number  (IAGP)
increased follicular B cell number  (IAGP)
increased grip strength  (IEA)
increased IgG3 level  (IAGP)
increased macrophage cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased pancreatic acinar cell number  (IAGP)
increased pancreatic alpha cell number  (IAGP)
increased plasmacytoid dendritic cell number  (IAGP)
increased single-positive T cell number  (IAGP)
increased splenocyte number  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
increased T cell number  (IAGP)
increased T cell proliferation  (IAGP)
loss of GABAergic neurons  (IAGP)
loss of vibrissae  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IEA)
no spontaneous movement  (IAGP)
pericardial effusion  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature hair loss  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
respiratory failure  (IAGP)
small pancreas  (IAGP)
small thymus  (IAGP)
thick aortic valve cusps  (IAGP)
thick epidermis  (IAGP)
trabecula carnea hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Cell and molecular biology of Notch. Fiuza UM and Arias AM, J Endocrinol. 2007 Sep;194(3):459-74.
2. HERP1 is a cell type-specific primary target of Notch. Iso T, etal., J Biol Chem 2002 Feb 22;277(8):6598-607.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Enhanced expression and autoimmunity of recombination signal binding protein-jkappa in human dilated cardiomyopathy. Nickenig G, etal., Biochem Biophys Res Commun. 1999 Dec 20;266(2):432-6.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway. Sweeney C, etal., FASEB J. 2004 Sep;18(12):1421-3. Epub 2004 Jul 9.
Additional References at PubMed
PMID:1740450   PMID:1950768   PMID:2556644   PMID:3104881   PMID:7566092   PMID:7588063   PMID:8406481   PMID:8749394   PMID:8889548   PMID:9102301   PMID:9111338   PMID:9418910  
PMID:9639038   PMID:9826771   PMID:10330372   PMID:10349636   PMID:10476967   PMID:10512203   PMID:10640276   PMID:10828593   PMID:11042159   PMID:11076861   PMID:11318877   PMID:11518718  
PMID:11532000   PMID:11544199   PMID:11604511   PMID:11937492   PMID:11967543   PMID:12039915   PMID:12145413   PMID:12154127   PMID:12477932   PMID:12520002   PMID:12593800   PMID:12594956  
PMID:12655061   PMID:12730123   PMID:12730124   PMID:12794108   PMID:12904583   PMID:12906797   PMID:14610273   PMID:14611647   PMID:14691545   PMID:14701881   PMID:15137944   PMID:15142529  
PMID:15226823   PMID:15465494   PMID:15466160   PMID:15489334   PMID:15509736   PMID:15689374   PMID:15782199   PMID:15840001   PMID:15866159   PMID:15959515   PMID:15991363   PMID:16000382  
PMID:16061358   PMID:16141072   PMID:16141073   PMID:16283144   PMID:16287852   PMID:16341126   PMID:16399505   PMID:16516838   PMID:16581056   PMID:16651378   PMID:16782026   PMID:16782866  
PMID:16867989   PMID:17015435   PMID:17079689   PMID:17080428   PMID:17095659   PMID:17210915   PMID:17229764   PMID:17242367   PMID:17283045   PMID:17336907   PMID:17360543   PMID:17392792  
PMID:17457934   PMID:17476283   PMID:17526737   PMID:17537790   PMID:17591855   PMID:17658278   PMID:17658279   PMID:17681139   PMID:17685488   PMID:17698590   PMID:17709399   PMID:17803961  
PMID:17849436   PMID:17915208   PMID:17938243   PMID:17967808   PMID:17984302   PMID:18096813   PMID:18198335   PMID:18287091   PMID:18287559   PMID:18337488   PMID:18381292   PMID:18397755  
PMID:18417619   PMID:18463680   PMID:18495817   PMID:18507503   PMID:18547789   PMID:18579678   PMID:18588871   PMID:18635610   PMID:18663143   PMID:18665263   PMID:18694942   PMID:18760388  
PMID:18777163   PMID:18786687   PMID:18799693   PMID:18824566   PMID:18836481   PMID:18838555   PMID:18852283   PMID:18950867   PMID:18976936   PMID:19065680   PMID:19107229   PMID:19124651  
PMID:19135161   PMID:19154718   PMID:19155301   PMID:19168137   PMID:19211676   PMID:19234458   PMID:19287095   PMID:19327148   PMID:19357083   PMID:19369401   PMID:19389370   PMID:19501584  
PMID:19502490   PMID:19525946   PMID:19542352   PMID:19557146   PMID:19573812   PMID:19590010   PMID:19641016   PMID:19666558   PMID:19779553   PMID:19828801   PMID:19859544   PMID:19895548  
PMID:19897741   PMID:19914235   PMID:20008296   PMID:20017954   PMID:20048339   PMID:20059953   PMID:20133625   PMID:20174635   PMID:20203209   PMID:20231316   PMID:20231432   PMID:20335360  
PMID:20360386   PMID:20362541   PMID:20378824   PMID:20379195   PMID:20398665   PMID:20412781   PMID:20418906   PMID:20420708   PMID:20446924   PMID:20452319   PMID:20499347   PMID:20501839  
PMID:20511547   PMID:20634318   PMID:20639863   PMID:20691157   PMID:20829372   PMID:20856205   PMID:20870902   PMID:20870935   PMID:20889548   PMID:20890042   PMID:20943920   PMID:20950430  
PMID:20978353   PMID:21093322   PMID:21112567   PMID:21123947   PMID:21168915   PMID:21238454   PMID:21252157   PMID:21267458   PMID:21270765   PMID:21282114   PMID:21282722   PMID:21311046  
PMID:21352545   PMID:21372128   PMID:21397841   PMID:21402740   PMID:21420948   PMID:21443869   PMID:21469122   PMID:21493891   PMID:21510873   PMID:21624358   PMID:21624937   PMID:21632926  
PMID:21633169   PMID:21637838   PMID:21731673   PMID:21731759   PMID:21737748   PMID:21750033   PMID:21750232   PMID:21773950   PMID:21791528   PMID:21804540   PMID:21841793   PMID:21873635  
PMID:21898486   PMID:22018469   PMID:22045613   PMID:22069237   PMID:22101730   PMID:22146645   PMID:22232070   PMID:22232429   PMID:22249448   PMID:22258620   PMID:22267218   PMID:22274697  
PMID:22275127   PMID:22275227   PMID:22279058   PMID:22279105   PMID:22323600   PMID:22354840   PMID:22354871   PMID:22354878   PMID:22365664   PMID:22396647   PMID:22426001   PMID:22457635  
PMID:22461559   PMID:22514327   PMID:22610140   PMID:22615412   PMID:22665065   PMID:22675211   PMID:22682244   PMID:22711842   PMID:22718343   PMID:22719978   PMID:22797898   PMID:22897852  
PMID:22915591   PMID:22926762   PMID:22933629   PMID:22940113   PMID:22991339   PMID:23110206   PMID:23117660   PMID:23136394   PMID:23138187   PMID:23197712   PMID:23213461   PMID:23223288  
PMID:23224519   PMID:23315998   PMID:23319657   PMID:23416099   PMID:23474530   PMID:23481390   PMID:23520387   PMID:23571214   PMID:23604909   PMID:23615612   PMID:23636056   PMID:23639443  
PMID:23651858   PMID:23675446   PMID:23684747   PMID:23698100   PMID:23775085   PMID:23785053   PMID:23825310   PMID:23826407   PMID:23830865   PMID:23832089   PMID:23839930   PMID:23884446  
PMID:23913046   PMID:23946445   PMID:24153254   PMID:24194600   PMID:24226518   PMID:24290140   PMID:24337118   PMID:24353058   PMID:24391519   PMID:24413398   PMID:24480830   PMID:24491691  
PMID:24549417   PMID:24583262   PMID:24586644   PMID:24603501   PMID:24631193   PMID:24637115   PMID:24643801   PMID:24647000   PMID:24711412   PMID:24812208   PMID:24904090   PMID:24906150  
PMID:24909139   PMID:24927569   PMID:24952961   PMID:24971735   PMID:24996169   PMID:25005473   PMID:25016959   PMID:25024136   PMID:25038826   PMID:25100656   PMID:25145286   PMID:25189209  
PMID:25203324   PMID:25209249   PMID:25234168   PMID:25301628   PMID:25324571   PMID:25329696   PMID:25344724   PMID:25378482   PMID:25406395   PMID:25429074   PMID:25432929   PMID:25468970  
PMID:25501905   PMID:25515406   PMID:25535389   PMID:25555218   PMID:25564622   PMID:25607460   PMID:25658372   PMID:25715395   PMID:25786100   PMID:25822340   PMID:25835502   PMID:25907274  
PMID:25915586   PMID:25918341   PMID:25936505   PMID:25961456   PMID:25995356   PMID:26054850   PMID:26138479   PMID:26147083   PMID:26188077   PMID:26271103   PMID:26302407   PMID:26318021  
PMID:26437242   PMID:26491108   PMID:26534985   PMID:26578715   PMID:26651607   PMID:26669487   PMID:26689699   PMID:26742650   PMID:26759236   PMID:26786414   PMID:26858409   PMID:26940862  
PMID:26950423   PMID:27056911   PMID:27079877   PMID:27112428   PMID:27141929   PMID:27183593   PMID:27188577   PMID:27240887   PMID:27246713   PMID:27294523   PMID:27339903   PMID:27346359  
PMID:27357444   PMID:27358050   PMID:27496872   PMID:27510977   PMID:27612641   PMID:27633993   PMID:27659682   PMID:27680285   PMID:27695000   PMID:27794430   PMID:27821617   PMID:27923395  
PMID:27939883   PMID:28009085   PMID:28051360   PMID:28077598   PMID:28087631   PMID:28174252   PMID:28192800   PMID:28215940   PMID:28238683   PMID:28267151   PMID:28395734   PMID:28401892  
PMID:28414328   PMID:28423318   PMID:28434801   PMID:28440309   PMID:28455378   PMID:28487372   PMID:28493549   PMID:28530678   PMID:28538179   PMID:28561022   PMID:28637720   PMID:28648363  
PMID:28673966   PMID:28695891   PMID:28700664   PMID:28714968   PMID:28790030   PMID:28825702   PMID:28856719   PMID:28916710   PMID:29030483   PMID:29038527   PMID:29095923   PMID:29109283  
PMID:29113990   PMID:29126263   PMID:29241683   PMID:29242273   PMID:29248546   PMID:29311361   PMID:29337183   PMID:29386140   PMID:29388792   PMID:29395868   PMID:29422515   PMID:29449332  
PMID:29515034   PMID:29578405   PMID:29649410   PMID:29688375   PMID:29720662   PMID:29739871   PMID:29743679   PMID:29773667   PMID:29795344   PMID:29844119   PMID:29885287   PMID:29899142  
PMID:29977079   PMID:30001316   PMID:30065940   PMID:30105024   PMID:30134068   PMID:30213224   PMID:30366956   PMID:30375986   PMID:30416072   PMID:30428088   PMID:30467111   PMID:30586708  
PMID:30596653   PMID:30673607   PMID:30702346   PMID:30799025   PMID:30916347   PMID:30932281   PMID:30958266   PMID:30962454   PMID:31043605   PMID:31071093   PMID:31118412   PMID:31165749  
PMID:31249304   PMID:31266773   PMID:31412250   PMID:31564613   PMID:31615108   PMID:31772299   PMID:31870258   PMID:31908034   PMID:31944217   PMID:31988190   PMID:32007475   PMID:32075915  
PMID:32084390   PMID:32098917   PMID:32147304   PMID:32341550   PMID:32467237   PMID:32719678   PMID:32780108   PMID:32907369   PMID:32929274   PMID:33053356   PMID:33148887   PMID:33299176  
PMID:33512383   PMID:33915108   PMID:33963183   PMID:34035082   PMID:34050174   PMID:34267243   PMID:34321999   PMID:34339855   PMID:34370006   PMID:34487959   PMID:34571841   PMID:34582748  
PMID:35103284   PMID:35137455   PMID:35228746   PMID:35263597   PMID:35294891   PMID:35440634   PMID:35444273   PMID:35451473   PMID:35575097   PMID:35577801   PMID:35661443   PMID:35686648  
PMID:35716334   PMID:35803280   PMID:35835555   PMID:35942101   PMID:36129169   PMID:36194632   PMID:36200806   PMID:36253375   PMID:36318272   PMID:36441145   PMID:37051908   PMID:37543088  
PMID:37680624   PMID:37751417   PMID:37756541   PMID:37865314   PMID:38051594   PMID:38355793  


Genomics

Comparative Map Data
Rbpj
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39553,713,121 - 53,814,787 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl553,623,494 - 53,814,704 (+)EnsemblGRCm39 Ensembl
GRCm38553,555,779 - 53,657,445 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl553,466,152 - 53,657,362 (+)EnsemblGRCm38mm10GRCm38
MGSCv37553,947,018 - 54,048,684 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36553,878,593 - 53,944,281 (+)NCBIMGSCv36mm8
Celera550,938,216 - 51,041,035 (+)NCBICelera
Cytogenetic Map5C1NCBI
cM Map529.37NCBI
RBPJ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38426,105,449 - 26,435,131 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl426,163,455 - 26,435,131 (+)EnsemblGRCh38hg38GRCh38
GRCh37426,165,080 - 26,436,753 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36425,930,430 - 26,042,376 (+)NCBINCBI36Build 36hg18NCBI36
Celera426,771,681 - 26,884,040 (+)NCBICelera
Cytogenetic Map4p15.2NCBI
HuRef425,659,979 - 25,775,063 (+)NCBIHuRef
CHM1_1426,322,549 - 26,437,875 (+)NCBICHM1_1
T2T-CHM13v2.0426,087,631 - 26,420,111 (+)NCBIT2T-CHM13v2.0
Rbpj
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81461,551,366 - 61,736,220 (-)NCBIGRCr8
mRatBN7.21457,338,493 - 57,523,330 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1457,338,507 - 57,523,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1461,746,363 - 61,809,045 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01463,048,700 - 63,111,484 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01459,445,481 - 59,508,257 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01459,657,738 - 59,865,427 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1459,658,935 - 59,735,450 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01459,785,053 - 59,859,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1456,447,546 - 56,510,235 (-)NCBICelera
Cytogenetic Map14q11NCBI
Rbpj
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544318,783,061 - 18,910,228 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544318,783,061 - 19,029,441 (-)NCBIChiLan1.0ChiLan1.0
RBPJ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2326,573,771 - 26,689,708 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1426,766,523 - 26,881,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0420,719,548 - 20,835,439 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1425,996,223 - 26,107,683 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl425,995,263 - 26,107,683 (+)Ensemblpanpan1.1panPan2
RBPJ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1384,060,417 - 84,286,008 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl384,064,440 - 84,286,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha386,572,469 - 86,797,897 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0385,030,006 - 85,255,529 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl385,034,041 - 85,255,924 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1384,151,949 - 84,377,265 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0384,271,690 - 84,496,976 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0384,656,440 - 84,881,337 (-)NCBIUU_Cfam_GSD_1.0
Rbpj
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528549,648,938 - 49,859,262 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364773,349,627 - 3,461,797 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364773,354,336 - 3,445,248 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBPJ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl819,922,779 - 20,166,754 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1819,933,035 - 20,166,746 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2820,306,820 - 20,540,623 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RBPJ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12723,911,084 - 24,023,856 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604770,424,032 - 70,537,613 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbpj
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247556,176,497 - 6,298,225 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247556,176,497 - 6,298,034 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbpj
3002 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4194
Count of miRNA genes:652
Interacting mature miRNAs:862
Transcripts:ENSMUST00000037618, ENSMUST00000087360, ENSMUST00000113865
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53102427565024480Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53102427565024480Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53157045865570458Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53348866767488876Mouse
1301845Lxw4_mlupus BXSB x NZW 4 (mouse)Not determined53569446269694594Mouse
11049561Lmr24e_mleishmaniasis resistance 24e (mouse)53569446269694594Mouse
11049559Lmr24c_mleishmaniasis resistance 24c (mouse)53569446269694594Mouse
11049558Lmr24b_mleishmaniasis resistance 24b (mouse)53569446269694594Mouse
1301223Hdlq7_mHDL QTL 7 (mouse)Not determined53585456869854714Mouse
13464252Ahl10_mage related hearing loss, early onset 10 (mouse)53585456869854714Mouse
4141647Hrvhf1_mheart rate variability, high frequency 1 (mouse)Not determined3643342370433423Mouse
1301170Lith13_mlithogenic gene 13 (mouse)Not determined53649448670494598Mouse
1300926Hpi2_mhepatic PMN infiltration 2 (mouse)Not determined53758148864806579Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
13464246Ahl11_mage related hearing loss, early onset 11 (mouse)53764377771643896Mouse
1300951Gbvq1_mgallstone bladder volume QTL 1 (mouse)Not determined53811168172111798Mouse
13464245Ahl12_mage related hearing loss, early onset 12 (mouse)53811168172111798Mouse
1301698Pcfm4_mperiosteal circumference and femur length 4 (mouse)Not determined54458584378585965Mouse
13207584Mwmlpt4_mMorris water maze latency to platform, training, 4 (mouse)54632260680322606Mouse
13207588Mwmlpa4_mMorris water maze latency to platform, all, 4 (mouse)54632260680322606Mouse
14746981Manh57_mmandible shape 57 (mouse)54716974281169742Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse

Markers in Region
Rbpj  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37554,043,916 - 54,044,415UniSTSGRCm37
MGSCv37646,479,584 - 46,480,082UniSTSGRCm37
Celera646,418,607 - 46,419,105UniSTS
X17459  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38646,529,110 - 46,529,270UniSTSGRCm38
GRCm38553,653,701 - 53,653,861UniSTSGRCm38
MGSCv37646,479,109 - 46,479,269UniSTSGRCm37
MGSCv37554,044,940 - 54,045,100UniSTSGRCm37
Celera551,037,299 - 51,037,459UniSTS
Cytogenetic Map5C1-C3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map6B2UniSTS
Whitehead_YAC6 UniSTS
AI843960  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38553,657,078 - 53,657,227UniSTSGRCm38
MGSCv37554,048,317 - 54,048,466UniSTSGRCm37
Celera551,040,668 - 51,040,817UniSTS
Cytogenetic Map5C1-C3UniSTS
Whitehead/MRC_RH5747.96UniSTS
Rbpsuh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38646,530,069 - 46,530,294UniSTSGRCm38
GRCm38553,649,395 - 53,649,774UniSTSGRCm38
MGSCv37646,480,068 - 46,480,293UniSTSGRCm37
MGSCv37554,040,634 - 54,041,013UniSTSGRCm37
Celera551,032,110 - 51,032,489UniSTS
Celera646,419,091 - 46,419,316UniSTS
Cytogenetic Map5C1-C3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map6B2UniSTS
cM Map537.5UniSTS
Rbpsuh-rs3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38646,529,866 - 46,530,489UniSTSGRCm38
MGSCv37646,479,865 - 46,480,488UniSTSGRCm37
Celera646,418,888 - 46,419,511UniSTS
Cytogenetic Map5C1-C3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map6B2UniSTS
cM Map634.0UniSTS
Rbpsuh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38553,650,071 - 53,651,371UniSTSGRCm38
MGSCv37554,041,310 - 54,042,610UniSTSGRCm37
Celera551,032,786 - 51,034,273UniSTS
Cytogenetic Map5C1-C3UniSTS
cM Map537.5UniSTS
Rbpj  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38553,652,677 - 53,653,176UniSTSGRCm38
MGSCv37554,043,916 - 54,044,415UniSTSGRCm37
Cytogenetic Map5C1-C3UniSTS
Rbpj  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38646,529,585 - 46,530,083UniSTSGRCm38
MGSCv37646,479,584 - 46,480,082UniSTSGRCm37
Celera646,418,607 - 46,419,105UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map6B2UniSTS
Cytogenetic Map5C1-C3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001080927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001080928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC084054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH001959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY512934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB839243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY107008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY155397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY171919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY716845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD540070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S63463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X17459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X58337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y18248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000037618   ⟹   ENSMUSP00000040694
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,747,556 - 53,814,704 (+)Ensembl
GRCm38.p6 Ensembl553,590,214 - 53,657,362 (+)Ensembl
RefSeq Acc Id: ENSMUST00000087360   ⟹   ENSMUSP00000084618
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,713,176 - 53,814,700 (+)Ensembl
GRCm38.p6 Ensembl553,555,834 - 53,657,358 (+)Ensembl
RefSeq Acc Id: ENSMUST00000113865   ⟹   ENSMUSP00000109496
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,747,813 - 53,814,704 (+)Ensembl
GRCm38.p6 Ensembl553,590,471 - 53,657,362 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200856
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,782,256 - 53,799,407 (+)Ensembl
GRCm38.p6 Ensembl553,624,914 - 53,642,065 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201701
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,782,419 - 53,799,407 (+)Ensembl
GRCm38.p6 Ensembl553,625,077 - 53,642,065 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201721
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,713,048 - 53,714,566 (+)Ensembl
GRCm38.p6 Ensembl553,555,706 - 53,557,224 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201883   ⟹   ENSMUSP00000143846
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,748,323 - 53,813,479 (+)Ensembl
GRCm38.p6 Ensembl553,590,981 - 53,656,137 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201912   ⟹   ENSMUSP00000143866
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,747,710 - 53,814,704 (+)Ensembl
GRCm38.p6 Ensembl553,590,368 - 53,657,362 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201928
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,776,778 - 53,803,321 (+)Ensembl
GRCm38.p6 Ensembl553,619,436 - 53,645,979 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201991   ⟹   ENSMUSP00000144617
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,623,494 - 53,806,732 (+)Ensembl
GRCm38.p6 Ensembl553,466,152 - 53,649,390 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202092
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,803,080 - 53,808,801 (+)Ensembl
GRCm38.p6 Ensembl553,645,738 - 53,651,459 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202476
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl553,795,974 - 53,799,409 (+)Ensembl
GRCm38.p6 Ensembl553,638,632 - 53,642,067 (+)Ensembl
RefSeq Acc Id: NM_001080927   ⟹   NP_001074396
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,747,828 - 53,814,787 (+)NCBI
GRCm38553,590,486 - 53,657,445 (+)NCBI
MGSCv37553,947,018 - 54,048,684 (+)RGD
Celera550,938,216 - 51,041,035 (+)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001080928   ⟹   NP_001074397
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,713,121 - 53,814,787 (+)NCBI
GRCm38553,555,779 - 53,657,445 (+)NCBI
MGSCv37553,947,018 - 54,048,684 (+)RGD
Celera550,938,216 - 51,041,035 (+)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001277116   ⟹   NP_001264045
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,747,688 - 53,814,787 (+)NCBI
GRCm38553,590,346 - 53,657,445 (+)NCBI
Celera550,938,216 - 51,041,035 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001359152   ⟹   NP_001346081
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,747,828 - 53,814,787 (+)NCBI
GRCm38553,590,486 - 53,657,445 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009035   ⟹   NP_033061
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,747,688 - 53,814,787 (+)NCBI
GRCm38553,590,346 - 53,657,445 (+)NCBI
MGSCv37553,947,018 - 54,048,684 (+)RGD
Celera550,938,216 - 51,041,035 (+)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006503796   ⟹   XP_006503859
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,766,548 - 53,814,703 (+)NCBI
GRCm38553,609,226 - 53,657,361 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006503799   ⟹   XP_006503862
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,748,296 - 53,814,703 (+)NCBI
GRCm38553,590,930 - 53,657,361 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036164920   ⟹   XP_036020813
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,753,509 - 53,814,703 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036164921   ⟹   XP_036020814
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39553,759,204 - 53,814,703 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001074396 (Get FASTA)   NCBI Sequence Viewer  
  NP_001074397 (Get FASTA)   NCBI Sequence Viewer  
  NP_001264045 (Get FASTA)   NCBI Sequence Viewer  
  NP_001346081 (Get FASTA)   NCBI Sequence Viewer  
  NP_033061 (Get FASTA)   NCBI Sequence Viewer  
  XP_006503859 (Get FASTA)   NCBI Sequence Viewer  
  XP_006503862 (Get FASTA)   NCBI Sequence Viewer  
  XP_036020813 (Get FASTA)   NCBI Sequence Viewer  
  XP_036020814 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA39018 (Get FASTA)   NCBI Sequence Viewer  
  AAA39019 (Get FASTA)   NCBI Sequence Viewer  
  AAA39020 (Get FASTA)   NCBI Sequence Viewer  
  AAA39021 (Get FASTA)   NCBI Sequence Viewer  
  AAA39022 (Get FASTA)   NCBI Sequence Viewer  
  AAA39023 (Get FASTA)   NCBI Sequence Viewer  
  AAB20195 (Get FASTA)   NCBI Sequence Viewer  
  AAH51387 (Get FASTA)   NCBI Sequence Viewer  
  AAR87804 (Get FASTA)   NCBI Sequence Viewer  
  BAC37889 (Get FASTA)   NCBI Sequence Viewer  
  BAE26281 (Get FASTA)   NCBI Sequence Viewer  
  BAE31773 (Get FASTA)   NCBI Sequence Viewer  
  CAA35501 (Get FASTA)   NCBI Sequence Viewer  
  CAB38078 (Get FASTA)   NCBI Sequence Viewer  
  CAB38079 (Get FASTA)   NCBI Sequence Viewer  
  EDL37679 (Get FASTA)   NCBI Sequence Viewer  
  EDL37680 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000040694
  ENSMUSP00000040694.7
  ENSMUSP00000084618
  ENSMUSP00000084618.3
  ENSMUSP00000109496
  ENSMUSP00000109496.2
  ENSMUSP00000143846
  ENSMUSP00000143846.2
  ENSMUSP00000143866
  ENSMUSP00000143866.2
  ENSMUSP00000144617.2
GenBank Protein P31266 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001074397   ⟸   NM_001080928
- Peptide Label: isoform 3
- UniProtKB: E9Q7W0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_033061   ⟸   NM_009035
- Peptide Label: isoform 1
- UniProtKB: Q80UN8 (UniProtKB/Swiss-Prot),   Q8C4Z3 (UniProtKB/Swiss-Prot),   P31266 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001074396   ⟸   NM_001080927
- Peptide Label: isoform 2
- UniProtKB: Q3UM17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264045   ⟸   NM_001277116
- Peptide Label: isoform 4
- UniProtKB: A0A0J9YTV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503862   ⟸   XM_006503799
- Peptide Label: isoform X2
- UniProtKB: Q3U6F1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503859   ⟸   XM_006503796
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001346081   ⟸   NM_001359152
- Peptide Label: isoform 5
RefSeq Acc Id: ENSMUSP00000109496   ⟸   ENSMUST00000113865
RefSeq Acc Id: ENSMUSP00000084618   ⟸   ENSMUST00000087360
RefSeq Acc Id: ENSMUSP00000040694   ⟸   ENSMUST00000037618
RefSeq Acc Id: ENSMUSP00000144617   ⟸   ENSMUST00000201991
RefSeq Acc Id: ENSMUSP00000143866   ⟸   ENSMUST00000201912
RefSeq Acc Id: ENSMUSP00000143846   ⟸   ENSMUST00000201883
RefSeq Acc Id: XP_036020813   ⟸   XM_036164920
- Peptide Label: isoform X2
- UniProtKB: Q3U6F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036020814   ⟸   XM_036164921
- Peptide Label: isoform X2
- UniProtKB: Q3U6F1 (UniProtKB/TrEMBL)
Protein Domains
Beta-trefoil DNA-binding   IPT/TIG   RBP-J/Cbf11/Cbf12 DNA binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P31266-F1-model_v2 AlphaFold P31266 1-526 view protein structure

Promoters
RGD ID:6886702
Promoter ID:EPDNEW_M6802
Type:multiple initiation site
Name:Rbpj_3
Description:Mus musculus recombination signal binding protein for immunoglobulinkappa J region , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6803  EPDNEW_M6804  EPDNEW_M6805  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38553,555,811 - 53,555,871EPDNEW
RGD ID:6886704
Promoter ID:EPDNEW_M6803
Type:initiation region
Name:Rbpj_1
Description:Mus musculus recombination signal binding protein for immunoglobulinkappa J region , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6802  EPDNEW_M6804  EPDNEW_M6805  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38553,590,369 - 53,590,429EPDNEW
RGD ID:6886706
Promoter ID:EPDNEW_M6804
Type:initiation region
Name:Rbpj_2
Description:Mus musculus recombination signal binding protein for immunoglobulinkappa J region , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6802  EPDNEW_M6803  EPDNEW_M6805  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38553,590,507 - 53,590,567EPDNEW
RGD ID:6886708
Promoter ID:EPDNEW_M6805
Type:initiation region
Name:Rbpj_4
Description:Mus musculus recombination signal binding protein for immunoglobulinkappa J region , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6802  EPDNEW_M6803  EPDNEW_M6804  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38553,590,690 - 53,590,750EPDNEW
RGD ID:6838202
Promoter ID:MM_KWN:42289
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:NM_001080928
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36553,946,841 - 53,947,341 (+)MPROMDB
RGD ID:6838204
Promoter ID:MM_KWN:42290
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4
Transcripts:NM_001080927,   NM_009035
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36553,980,461 - 53,981,877 (+)MPROMDB
RGD ID:6838206
Promoter ID:MM_KWN:42291
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Lung
Transcripts:UC008XLK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36553,982,121 - 53,982,621 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96522 AgrOrtholog
Ensembl Genes ENSMUSG00000039191 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000037618 ENTREZGENE
  ENSMUST00000037618.13 UniProtKB/Swiss-Prot
  ENSMUST00000087360 ENTREZGENE
  ENSMUST00000087360.9 UniProtKB/TrEMBL
  ENSMUST00000113865 ENTREZGENE
  ENSMUST00000113865.5 UniProtKB/Swiss-Prot
  ENSMUST00000201883 ENTREZGENE
  ENSMUST00000201883.4 UniProtKB/TrEMBL
  ENSMUST00000201912 ENTREZGENE
  ENSMUST00000201912.4 UniProtKB/TrEMBL
  ENSMUST00000201991.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.80.10.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Beta-trefoil_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTD_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CLS_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBP-J/Cbf11/Cbf12_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBP-J/Cbf11/Cbf12_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBP-Jkappa_IPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19664 UniProtKB/Swiss-Prot
MGD MGI:96522 ENTREZGENE
NCBI Gene 19664 ENTREZGENE
PANTHER PTHR10665 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BTD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LAG1-DNAbind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIG_SUH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rbpj PhenoGen
SMART BTD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LAG1_DNAbind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF110217 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0J9YTV5 ENTREZGENE, UniProtKB/TrEMBL
  A0A0J9YVE0_MOUSE UniProtKB/TrEMBL
  E9Q7W0 ENTREZGENE, UniProtKB/TrEMBL
  P31266 ENTREZGENE
  Q3U6F1 ENTREZGENE, UniProtKB/TrEMBL
  Q3UM17 ENTREZGENE, UniProtKB/TrEMBL
  Q6R5E9_MOUSE UniProtKB/TrEMBL
  Q80UN8 ENTREZGENE
  Q8C4Z3 ENTREZGENE
  SUH_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q80UN8 UniProtKB/Swiss-Prot
  Q8C4Z3 UniProtKB/Swiss-Prot