Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Psmd5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PSMD5 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PSMD5 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PSMD5 mRNA | CTD | PMID:22206623 | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | PSMD5 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to PSMD5 protein | CTD | PMID:32991956 | 1-nitropyrene | increases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | 1-nitropyrene results in increased expression of PSMD5 mRNA | CTD | PMID:19041380 | 17alpha-ethynylestradiol | affects expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol affects the expression of PSMD5 mRNA | CTD | PMID:20170705 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of PSMD5 mRNA | CTD | PMID:19693291 | 17beta-estradiol | multiple interactions | ISO | Psmd5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of PSMD5 mRNA | CTD | PMID:26496021 | 1H-pyrazole | increases expression | EXP | | 6480464 | pyrazole results in increased expression of PSMD5 mRNA | CTD | PMID:17945193 | 2,4,6-trinitrotoluene | affects expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Trinitrotoluene affects the expression of PSMD5 mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of PSMD5 mRNA | CTD | PMID:21346803 | 2-methoxyethanol | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | methyl cellosolve results in increased expression of PSMD5 mRNA | CTD | PMID:21061450 | 3H-1,2-dithiole-3-thione | increases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in increased expression of PSMD5 mRNA | CTD | PMID:15375163 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PSMD5 mRNA | CTD | PMID:19770486 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | affects expression | ISO | PSMD5 (Homo sapiens) | 6480464 | bisphenol A affects the expression of PSMD5 mRNA | CTD | PMID:20170705 | bisphenol A | increases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PSMD5 protein | CTD | PMID:34186270 and PMID:37567409 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PSMD5 mRNA | CTD | PMID:33221593 | bisphenol A | decreases methylation | ISO | Psmd5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased methylation of PSMD5 gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PSMD5 mRNA | CTD | PMID:25181051 more ... | bisphenol A | multiple interactions | ISO | Psmd5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of PSMD5 mRNA | CTD | PMID:26496021 | bromobenzene | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | bromobenzene results in increased expression of PSMD5 mRNA | CTD | PMID:12628495 | cadmium dichloride | increases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of PSMD5 mRNA | CTD | PMID:26472689 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of PSMD5 mRNA | CTD | PMID:23811191 | cobalt dichloride | increases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of PSMD5 mRNA | CTD | PMID:19376846 | cobalt dichloride | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of PSMD5 mRNA | CTD | PMID:24386269 | doxorubicin | decreases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PSMD5 mRNA | CTD | PMID:29803840 | endosulfan | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of PSMD5 mRNA | CTD | PMID:29391264 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of PSMD5 mRNA | CTD | PMID:30319688 | flutamide | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of PSMD5 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PSMD5 mRNA | CTD | PMID:22206623 | furan | increases methylation | ISO | Psmd5 (Rattus norvegicus) | 6480464 | furan results in increased methylation of PSMD5 gene | CTD | PMID:22079235 | gentamycin | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of PSMD5 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Glafenine results in decreased expression of PSMD5 mRNA | CTD | PMID:24136188 | glyphosate | decreases expression | EXP | | 6480464 | Glyphosate results in decreased expression of PSMD5 protein | CTD | PMID:36173347 | hypochlorous acid | increases expression | EXP | | 6480464 | Hypochlorous Acid results in increased expression of PSMD5 mRNA | CTD | PMID:19376150 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PSMD5 mRNA | CTD | PMID:36331819 | isoprenaline | multiple interactions | ISO | Psmd5 (Rattus norvegicus) | 6480464 | [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD5 mRNA | CTD | PMID:30303030 | ivermectin | decreases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PSMD5 protein | CTD | PMID:32959892 | ketoconazole | increases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Ketoconazole results in increased expression of PSMD5 mRNA | CTD | PMID:36621641 | lead(0) | affects expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Lead affects the expression of PSMD5 mRNA | CTD | PMID:28903495 | leflunomide | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | leflunomide results in increased expression of PSMD5 mRNA | CTD | PMID:24136188 | methoxychlor | increases methylation | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Methoxychlor results in increased methylation of PSMD5 gene | CTD | PMID:23303685 | nefazodone | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of PSMD5 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | nimesulide results in increased expression of PSMD5 mRNA | CTD | PMID:24136188 | oxaliplatin | multiple interactions | ISO | Psmd5 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of PSMD5 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PSMD5 mRNA | CTD | PMID:21420995 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of PSMD5 mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PSMD5 mRNA more ... | CTD | PMID:36331819 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of PSMD5 mRNA | CTD | PMID:23811191 | progesterone | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of PSMD5 mRNA | CTD | PMID:19693291 | progesterone | decreases expression | EXP | | 6480464 | Progesterone results in decreased expression of PSMD5 mRNA | CTD | PMID:19693291 | quercetin | decreases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of PSMD5 mRNA | CTD | PMID:21632981 | SB 431542 | multiple interactions | ISO | PSMD5 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of PSMD5 protein | CTD | PMID:37664457 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of PSMD5 mRNA | CTD | PMID:16014739 and PMID:25270620 | sunitinib | increases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PSMD5 mRNA | CTD | PMID:31533062 | testosterone | increases expression | EXP | | 6480464 | Testosterone results in increased expression of PSMD5 mRNA | CTD | PMID:19693291 | testosterone | decreases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of PSMD5 mRNA | CTD | PMID:33359661 | tetrachloromethane | multiple interactions | ISO | Psmd5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PSMD5 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of PSMD5 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of PSMD5 mRNA | CTD | PMID:23411599 | topotecan | multiple interactions | ISO | Psmd5 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of PSMD5 mRNA | CTD | PMID:25729387 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PSMD5 mRNA | CTD | PMID:19448997 | triphenyl phosphate | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of PSMD5 mRNA | CTD | PMID:30589522 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of PSMD5 mRNA | CTD | PMID:33045310 | urethane | decreases expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Urethane results in decreased expression of PSMD5 mRNA | CTD | PMID:28818685 | valdecoxib | increases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | valdecoxib results in increased expression of PSMD5 mRNA | CTD | PMID:24136188 | valproic acid | affects expression | ISO | PSMD5 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PSMD5 mRNA | CTD | PMID:25979313 | vinclozolin | decreases expression | ISO | Psmd5 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of PSMD5 mRNA | CTD | PMID:23034163 | |