Gene: Vcl (vinculin)  Mus musculus

Symbol: Vcl
Name: vinculin
Description: ENCODES a protein that exhibits actin binding (ortholog); alpha-catenin binding (ortholog); dystroglycan binding (ortholog); INVOLVED IN cell adhesion; lamellipodium assembly; regulation of cell migration; PARTICIPATES IN E-cadherin signaling pathway; vascular endothelial growth factor signaling pathway; Entamoeba histolyca infection pathway; ASSOCIATED WITH abnormal brain ventricle morphology; abnormal cardiac muscle relaxation; abnormal cardiovascular system morphology; ASSOCIATED WITH Cardiomyopathy, Dilated (ortholog); Cardiomyopathy, Dilated, 1w (ortholog); Cardiomyopathy, Familial Hypertrophic, 15 (ortholog); FOUND IN adherens junction; cell-cell junction; costamere; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 9430097D22; AA571387; AI462105; AW545629; metavinculin; vinculin
Orthologs: Homo sapiens : VCL (vinculin)  HGNC
Rattus norvegicus : Vcl (vinculin)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381420,929,433 - 21,033,673+NCBI
Mouse cM Map1411.53 NCBI
Mouse Celera Assembly1417,309,615 - 17,412,913+NCBI
Mouse Genome Assembly Build 371421,748,655 - 21,852,895+NCBI
Mouse Genome Assembly Build 36.11421,748,655 - 21,852,895+NCBI
Mouse Cytogenetic Map14 A3 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Vcl
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1322561
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2013-04-30
Status: ACTIVE